Found 31 with Last Name = 'yakushiji' and Initial = 'f' 
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of porcine tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of porcine tubulin polymerization by spectrophotometryMore data for this Ligand-Target Pair
3D Structure (crystal)TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human recombinant myostatin pre-incubated with compound for 1 hr before addition to human HepG2 cells assessed as reduction in myostati...More data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 6.40nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 8.40nMAssay Description:Partial agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 2.20nMAssay Description:Partial agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Partial agonist activity at human NMUR1 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Mus musculus)
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 3nMAssay Description:Agonist activity at mouse NMUR2 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Mus musculus)
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 9.5nMAssay Description:Agonist activity at mouse NMUR1 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Mus musculus)
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 2.41E+3nMAssay Description:Agonist activity at mouse NMUR1 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Mus musculus)
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 156nMAssay Description:Agonist activity at mouse NMUR2 expressed in HEK293 cells by calcium mobilization assayMore data for this Ligand-Target Pair
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKd: 36nMAssay Description:Binding affinity to recombinant myostatin (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKd: 30nMAssay Description:Binding affinity to recombinant myostatin (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetGrowth/differentiation factor 8(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKd: 117nMAssay Description:Binding affinity to recombinant myostatin (unknown origin) by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.920nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 2.60nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.140nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 1(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 0.0830nMAssay Description:Agonist activity at human NMUR1 expressed in CHO cells assessed as intracellular calcium flux at by Fluo-4 AM dye based fluorometric imaging methodMore data for this Ligand-Target Pair
Affinity DataKd: 1.06E+3nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.79E+4nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 3.70E+3nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 2.52E+4nMAssay Description:Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.06E+3nMAssay Description:Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysisMore data for this Ligand-Target Pair
Affinity DataKd: 9.74E+3nMAssay Description:Binding affinity to pig tubulin after 1 hr by fluorescence quenching analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.06E+3nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
Affinity DataKd: 620nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetNeuromedin-U receptor 2(Homo sapiens (Human))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at human NMUR2 expressed in CHO cells by calcium mobilization assayMore data for this Ligand-Target Pair
Affinity DataKd: 200nMAssay Description:Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysisMore data for this Ligand-Target Pair
TargetTubulin alpha-1A/beta chain(Sus scrofa (Pig))
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Tokyo University Of Pharmacy And Life Sciences
Curated by ChEMBL
Affinity DataKd: 1.00E+3nMAssay Description:Binding affinity to porcine tubulin incubated for 1 hr by spectrofluorometryMore data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMAssay Description:Binding affinity to porcine tubulin incubated for 1 hr by spectrofluorometryMore data for this Ligand-Target Pair
