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Found 116 with Last Name = 'yamauchi-kohno' and Initial = 'r'
TargetEndothelin-1 receptor(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105033(CHEMBL112531 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataKi:  0.00420nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50369953(CHEMBL1627022)
Affinity DataKi:  0.0150nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50369953(CHEMBL1627022)
Affinity DataKi:  41nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105000(CHEMBL175616 | sodium salt of 4-tert-Butyl-N-[6-(2...)
Affinity DataKi:  81nMAssay Description:Ability to inhibit [125I]ET1 binding to human cloned endothelin A receptor expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105033(CHEMBL112531 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataKi:  130nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin receptor type B(Homo sapiens (Human))
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105000(CHEMBL175616 | sodium salt of 4-tert-Butyl-N-[6-(2...)
Affinity DataKi:  140nMAssay Description:Ability to inhibit [125I]-ET-1 binding to human cloned ETB receptors expressed on CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105033(CHEMBL112531 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50: <0.00100nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105035(CHEMBL325511 | N-{5-Benzo[1,3]dioxol-5-yl-6-[2-(5-...)
Affinity DataIC50:  0.00110nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104997(4-tert-Butyl-N-[6-[2-(5-methylsulfanyl-pyrimidin-2...)
Affinity DataIC50:  0.00170nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105034(4-tert-Butyl-N-{6-[2-(5-methoxy-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.00170nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107562(CHEMBL168119 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.00250nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105055(4-tert-Butyl-N-{6-[2-(5-hydroxymethyl-pyrimidin-2-...)
Affinity DataIC50:  0.00260nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105048(CHEMBL112144 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.00390nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105048(CHEMBL112144 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.00390nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107561(CHEMBL168441 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.00530nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105051(CHEMBL112624 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.00620nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105047(Acetic acid ethyl ester4-tert-Butyl-N-{5-(3,4-dime...)
Affinity DataIC50:  0.00850nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104986(4-tert-Butyl-N-{5-(4-ethyl-phenyl)-6-[2-(5-methyls...)
Affinity DataIC50:  0.0130nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105040(4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(5-meth...)
Affinity DataIC50:  0.0150nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105026(CHEMBL115724 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.0180nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107567(CHEMBL170908 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.0260nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105025(4-tert-Butyl-N-{5-(3-methoxy-phenyl)-6-[2-(5-methy...)
Affinity DataIC50:  0.0280nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50369954(CHEMBL1627023)
Affinity DataIC50:  0.0340nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104988(4-tert-Butyl-N-{6-[2-(5-pyridin-2-yl-pyrimidin-2-y...)
Affinity DataIC50:  0.0360nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105033(CHEMBL112531 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.0390nMAssay Description:Ability to inhibit specific binding of [125I]- -ET-1 to rat A 10 cells which express endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104995(CHEMBL369489 | sodium salt of N-{6-[2-(5-Bromo-pyr...)
Affinity DataIC50:  0.0390nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105057(CHEMBL324184 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.0400nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105054(4-tert-Butyl-N-{5-(4-hydroxymethyl-phenyl)-6-[2-(5...)
Affinity DataIC50:  0.0400nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107556(CHEMBL170493 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.0430nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104992(CHEMBL114700 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.0510nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104992(CHEMBL114700 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.0510nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104991(4-tert-Butyl-N-[6-[2-(5-chloro-pyrimidin-2-yloxy)-...)
Affinity DataIC50:  0.0590nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105027(CHEMBL176272 | sodium salt of 4-tert-Butyl-N-{6-[2...)
Affinity DataIC50:  0.0800nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105042(4-tert-Butyl-N-{6-[2-(pyrimidin-2-yloxy)-ethoxy]-5...)
Affinity DataIC50:  0.110nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107558(CHEMBL167314 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.150nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105007(CHEMBL177924 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.160nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105029(4-tert-Butyl-N-[6-[2-(5-methylsulfanyl-pyrimidin-2...)
Affinity DataIC50:  0.160nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107568(CHEMBL168604 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.200nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104987(CHEMBL367445 | sodium salt of 4-tert-Butyl-N-{6-[2...)
Affinity DataIC50:  0.25nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104984(4-tert-Butyl-N-{6-[2-(5-methylsulfanyl-pyrimidin-2...)
Affinity DataIC50:  0.290nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50369953(CHEMBL1627022)
Affinity DataIC50:  0.330nMAssay Description:Ability to inhibit [125I]ET1 binding to endothelin A receptor in porcine aortic membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105003(4-tert-Butyl-N-{5-(2-methoxy-phenoxy)-6-[2-(5-meth...)
Affinity DataIC50:  0.370nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104993(CHEMBL177979 | sodium salt of 4-tert-Butyl-N-{6-[2...)
Affinity DataIC50:  0.420nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50107560(CHEMBL354528 | N-[6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.450nMAssay Description:In vitro inhibition of [125 I]ET-1 binding to Endothelin A receptor in porcine aortic membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104982(CHEMBL175501 | sodium salt of 4-tert-Butyl-N-{6-[2...)
Affinity DataIC50:  0.480nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105011(CHEMBL368796 | sodium salt of 4-tert-Butyl-N-{6-[2...)
Affinity DataIC50:  0.560nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105041(CHEMBL112162 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.640nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105019(CHEMBL111934 | N-{6-[2-(5-Bromo-pyrimidin-2-yloxy)...)
Affinity DataIC50:  0.760nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50105002(4-tert-Butyl-N-{5-(3-methoxy-phenoxy)-6-[2-(5-meth...)
Affinity DataIC50:  0.860nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(Sus scrofa)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50104983(4-tert-Butyl-N-{6-[2-(5-methylsulfanyl-pyrimidin-2...)
Affinity DataIC50:  0.890nMAssay Description:In vitro inhibition of [125I]-ET-1 binding to Endothelin A receptor in porcine aortic membrane from endothelial cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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