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Found 264 with Last Name = 'zhang' and Initial = 'mq'
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50009073(4-(5-cyclopentyloxycarbonylamino-1-methyl-1H-indol...)
Affinity DataKi:  0.300nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50052024(CHEMBL787 | montelukast)
Affinity DataKi:  0.5nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064085(CHEMBL285070 | N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-ch...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064083(7-{(E)-2-[3-(Quinolin-2-ylmethoxy)-phenyl]-vinyl}-...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064084(7-[3-(Quinolin-2-ylmethoxy)-benzyloxy]-2-(1H-tetra...)
Affinity DataKi:  3nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064086(CHEMBL283754 | Cinalukast | N-{3-[(E)-2-(4-Cyclobu...)
Affinity DataKi:  6.40nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50023198(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)
Affinity DataIC50:  1nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117612(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  2.60nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50366796(CHEMBL609440)
Affinity DataIC50:  4.5nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117595(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  4.60nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117614(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  6nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117618(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  7nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117577(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117594(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  8nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064072(4-Oxo-2-[3-(quinolin-2-ylmethoxy)-phenyl]-4H-chrom...)
Affinity DataIC50:  17nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117584(1-Benzyl-4-[3-(2,3-dihydro-benzofuran-5-yl)-3-oxo-...)
Affinity DataIC50:  17nMAssay Description:In vitro reversal of vecuronium-induced neuromuscular block in guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCysteinyl leukotriene receptor 1(GUINEA PIG)
Vrije Universiteit

Curated by ChEMBL
LigandPNGBDBM50064074(4-Oxo-2-[3-((E)-2-quinolin-2-yl-vinyl)-phenyl]-4H-...)
Affinity DataIC50:  17nMAssay Description:Binding affinity of the compound towards Cysteinyl leukotriene D4 receptor (cysLT1) was measured by the displacement of [3H]-LTD4 radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM8960((+/-)-2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimet...)
Affinity DataIC50:  18nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117574(1-Benzyl-1-methyl-4-[3-(5-methyl-1-phenyl-1H-pyraz...)
Affinity DataIC50:  22nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117583(1-Benzyl-4-(5,6-dimethoxy-1-oxo-indan-2-ylmethyl)-...)
Affinity DataIC50:  25nMAssay Description:In vitro reversal of vecuronium-induced neuromuscular block in guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117609(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  28nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117620(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  30nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50199518((-)-huperzine B | CHEMBL245079 | huperzine B)
Affinity DataIC50:  30nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117622(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  32nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117623(1-Cyclobutylmethyl-4-[3-(5,6-dimethoxy-benzo[b]thi...)
Affinity DataIC50:  40nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  43nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117576(1-Benzyl-4-[3-(6-methoxy-naphthalen-2-yl)-3-oxo-pr...)
Affinity DataIC50:  50nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117602(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  53nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117597(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  54nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117588(1-Benzyl-4-[3-(2,3-dihydro-benzofuran-5-yl)-3-oxo-...)
Affinity DataIC50:  66nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117611(1-tert-Butoxycarbonylmethyl-4-[3-(5,6-dimethoxy-be...)
Affinity DataIC50:  79nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117608(1-Benzyl-4-[2-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  90nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117578(1-Benzyl-4-[3-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117596(1-Cyclopropylmethyl-4-[3-(5,6-dimethoxy-benzo[b]th...)
Affinity DataIC50:  110nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117606(1-Benzyl-4-[5-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  110nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117585(1-Benzyl-4-[3-(5,6-dimethoxy-1-methyl-1H-indol-2-y...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117615(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  120nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117579(1-Benzyl-1-methyl-4-[3-oxo-3-(2,3,4,5-tetrahydro-b...)
Affinity DataIC50:  139nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  219nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117599(1-Benzyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  219nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117591(4-(3-Benzo[1,3]dioxol-5-yl-3-oxo-propyl)-1-benzyl-...)
Affinity DataIC50:  240nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117605(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  280nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50108395(Benzyl-{3-[2-(3,4-dimethoxy-phenyl)-2-oxo-ethoxy]-...)
Affinity DataIC50:  330nMAssay Description:In vitro inhibitory activity against human recombinant AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117600(1-Benzyl-4-[5-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  380nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117613(4-[3-(5,6-Dimethoxy-benzo[b]thiophen-2-yl)-3-oxo-p...)
Affinity DataIC50:  390nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50037157(3-(1-Benzyl-piperidin-4-yl)-1-(2,3,4,5-tetrahydro-...)
Affinity DataIC50: <500nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117580(1-Benzyl-1-methyl-4-[3-oxo-3-(2,3,4,5-tetrahydro-1...)
Affinity DataIC50: <500nMAssay Description:In vitro inhibition of human recombinant AChE.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117616(1-Benzyl-4-[2-(5,6-dimethoxy-benzo[b]thiophen-2-yl...)
Affinity DataIC50:  520nMAssay Description:Concentration required for the inhibition of acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50117603(1-Allyl-4-[3-(5,6-dimethoxy-benzo[b]thiophen-2-yl)...)
Affinity DataIC50:  540nMAssay Description:In vitro reversal of vecuronium-induced block in isolated guinea pig hemi-diaphragm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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