Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 87 hits for monomerid = 50072864,50072865,50072861,50073910,50073915,50073918,50073912,50073909,50073913,50073914,50087245,50085865,50093125,50099447,50099448,50099449,50099450,50099451,50099452,50102025,50102026,50118686,50118687,50122792,50122793,50122795,50122796,50122797,50129630,50129631,50129632,50129633,50129634,50139762,50139763,50139764,50143944,50161189,50168313,50168314,50168317,50168318,50168312,50193152,50208564,50208565,50208566,50208568,50208569,50208570,50208571,50336688
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Displacement of FITC-Ahx-PVPePYINQSVPKRK-NH2 from N-terminal His6-tagged human full length GRB2 (1 to 217 residues) expressed in Escherichia coli ass...More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Binding affinity for Growth factor receptor bound protein 2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding to p185erbB-2 receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Binding affinity for Growth factor receptor bound protein 2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 59nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.20nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 155nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Grb-SH2 domain binding to phosphorylated carboxy-terminal intracellular domain of epidermal growth factor receptorMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 500nMAssay Description:Inhibition of Grb2 SH2 domain binding in MDA-MB-453 human breast carcinoma cell lysatesMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in plasmon resonance binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKd: 260nMAssay Description:Dissociation constant of compound was determined from affinity of compound towards Growth factor receptor bound protein 2 measured by fluorescenceMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Growth factor receptor bound protein 2 binding by ELISA assay methodMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition of Grb2-SH2 domain binding to phospho-EGF receptor intracellular C-terminal domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibitory concentration required against Src homology (SH2) domain of Growth factor receptor bound protein 2 by ELISA binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain binding in ELISAMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKd: 0.0750nMAssay Description:Binding affinity to SH2 domain of GRB2More data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of SH2 domain of GRB2 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 700nMAssay Description:Inhibition against Growth factor receptor bound protein 2 binding using ELISA techniqueMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition against Growth factor receptor bound protein 2 binding using ELISA techniqueMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition against Growth factor receptor bound protein 2 binding using ELISA techniqueMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition against Growth factor receptor bound protein 2 binding using ELISA techniqueMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition against Growth factor receptor bound protein 2 binding using ELISA techniqueMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 4.79E+4nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain in extracellular binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 5.25E+4nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain in extracellular binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: >6.00E+5nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain in extracellular binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain in extracellular binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: >6.00E+5nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain in extracellular binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of Growth factor receptor bound protein 2 SH2 domain in extracellular binding assayMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKd: 0.0930nMAssay Description:In vitro binding affinity for Grb2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:In vitro binding affinity in extracellular ELISA-based assay for Grb2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:In vitro binding affinity in extracellular ELISA-based assay for Grb2 SH2 domainMore data for this Ligand-Target Pair
TargetGrowth factor receptor-bound protein 2(Homo sapiens (Human))
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
H. Lee Moffitt Cancer Center And Research Institute
Curated by ChEMBL
Affinity DataKd: 0.0750nMAssay Description:In vitro binding affinity for Grb2 SH2 domainMore data for this Ligand-Target Pair
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