Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 46 hits for monomerid = 50089616,50089617,50089618,50089619,50089620,50089621,50089622,50089623,50089624,50089625,50089626,50157911,50157912,50157913,50157914,50157915,50130210,50130204,50130205,50130206,50130207,50130208,50130209   

TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataKi:  1.70nMAssay Description:Inhibition of human acetylcholinesteraseMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataKi:  1.70nM ΔG°:  -12.0kcal/molepH: 7.0 T: 2°CAssay Description:Assays were conducted at 25 C in 20 mM sodium phosphate buffer (pH 7.0) and 0.01% bovine serum albumin unless otherwise noted. AChE concentrations we...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50157911(13a-hydroxy-10-(4-methoxyphenyl)-5,5,5a,7a,13b-pen...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity for AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089617(3,6-Dihydroxy-4-hydroxymethyl-9-(3-methoxy-phenyl)...)
Affinity DataIC50: >9.30E+4nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089618(9-(6-Chloro-pyridin-3-yl)-3,6-dihydroxy-4-hydroxym...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089620(3,6-Dihydroxy-4-hydroxymethyl-9-(4-methoxy-phenyl)...)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089621(4a,12a-Dihydroxy-9-(4-methoxy-phenyl)-4,4,6a,12b-t...)
Affinity DataIC50:  26nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089622(3,6-Dihydroxy-4-hydroxymethyl-4,6a,12b-trimethyl-9...)
Affinity DataIC50:  1.01E+5nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089623(3,6-Dihydroxy-4-hydroxymethyl-4,6a,12b-trimethyl-9...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089624(3,6-Dihydroxy-4-hydroxymethyl-4,6a,12b-trimethyl-9...)
Affinity DataIC50:  7.90E+3nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089625(9-(3,4-Dimethoxy-phenyl)-3,6-dihydroxy-4-hydroxyme...)
Affinity DataIC50:  5.80E+4nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089626(3,6-Dihydroxy-4-hydroxymethyl-4,6a,12b-trimethyl-9...)
Affinity DataIC50:  9.90E+4nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50157912(13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4,14,19,...)
Affinity DataIC50:  230nMAssay Description:Inhibitory concentration against Acetylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50157913(4a,12a-dihydroxy-3-methoxy-4,4,6a,12b-tetramethyl-...)
Affinity DataIC50:  420nMAssay Description:Inhibitory concentration against Acetylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50157914(4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-te...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration against Acetylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50157914(4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-te...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration against Butyrylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50157913(4a,12a-dihydroxy-3-methoxy-4,4,6a,12b-tetramethyl-...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration against Butyrylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50157915(4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-te...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration against Butyrylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50157911(13a-hydroxy-10-(4-methoxyphenyl)-5,5,5a,7a,13b-pen...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibitory concentration against Acetylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50157911(13a-hydroxy-10-(4-methoxyphenyl)-5,5,5a,7a,13b-pen...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitory concentration against Butyrylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50157915(4a,12a-dihydroxy-9-(4-methoxyphenyl)-4,4,6a,12b-te...)
Affinity DataIC50:  90nMAssay Description:Inhibitory concentration against Acetylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50157912(13-hydroxy-16-methoxy-8-(4-methoxyphenyl)-4,14,19,...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibitory concentration against Butyrylcholinesterase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50130204(CHEMBL3632858)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50130205(CHEMBL3632857)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50130206(CHEMBL3632856)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50130207(CHEMBL3632855)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50130208(CHEMBL3632854)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50130209(CHEMBL3632853)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50130210(CHEMBL3632852)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089621(4a,12a-Dihydroxy-9-(4-methoxy-phenyl)-4,4,6a,12b-t...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataIC50:  260nMAssay Description:Inhibition of electric eel AChE by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataIC50:  6nMAssay Description:Inhibition of AChE-induced amyloid beta aggregationMore data for this Ligand-Target Pair
TargetCholinesterase(Homo sapiens (Human))
Korea Research Institute Of Bioscience And Biotechnology

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of BChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human erythrocyte AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50130210(CHEMBL3632852)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50130210(CHEMBL3632852)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50130206(CHEMBL3632856)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
New York Structural Biology Center

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataIC50:  8nMAssay Description:Inhibitory activity against AcetylcholinesteraseMore data for this Ligand-Target Pair
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50089616(4a,12a-Dihydroxy-4,4,6a,12b-tetramethyl-9-(3,4,5-t...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of the compound against acyl-CoA:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
National Taiwan University

Curated by ChEMBL
LigandPNGBDBM50130206(CHEMBL3632856)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE incubated for 15 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSterol O-acyltransferase 1(Homo sapiens (Human))
Kitasato University

Curated by ChEMBL
LigandPNGBDBM50089619(9-(3,4-Dimethoxy-phenyl)-4a,12a-dihydroxy-4,4,6a,1...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of the compound against acyl-CoA:cholesterol acyltransferase (ACAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed