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Found 188 Enz. Inhib. hit(s) with Target = 'Adenomatous polyposis coli protein'
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM50094484(CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...)
Affinity DataKi:  8.31E+3nM ΔG°:  -29.0kJ/molepH: 7.4 T: 2°CAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM213748(US9284299, PKF115-584 | US9738628, Compound PKF115...)
Affinity DataKi:  5.39E+4nM ΔG°:  -24.4kJ/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM50094484(CHEBI:3556 | CHEMBL2323033 | US9284299, CGP049090 ...)
Affinity DataKi:  6.25E+4nM ΔG°:  -24.0kJ/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM32102(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)
Affinity DataKi:  6.62E+4nM ΔG°:  -23.9kJ/molepH: 7.4 T: 2°CAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM213761(US9284299, 12 | US9738628, Compound 12)
Affinity DataKi:  1.71E+5nM ΔG°:  -21.5kJ/molepH: 7.4 T: 2°CAssay Description:Experiments were performed in white opaque 384-well plates from PerkinElmer (Waltham, Mass.), and the samples were read on a Synergy 2 plate reader (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM32102(1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,...)
Affinity DataKi:  1.71E+5nM ΔG°:  -21.5kJ/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein [1477-1519]/Catenin beta-1 [138-686](Homo sapiens (Human))
University Of Utah Research Foundation

US Patent
LigandPNGBDBM213761(US9284299, 12 | US9738628, Compound 12)
Affinity DataKi:  1.76E+5nM ΔG°:  -21.4kJ/moleT: 2°CAssay Description:Experiments were performed in 96-well Microfluor 2 black plates (Waltham, Mass.), and the samples were read by a Synergy 2 plate reader (Biotek, Wino...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM273137(US10071086, Compound 443)
Affinity DataIC50:  1nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269261(US10071086, Compound 9)
Affinity DataIC50:  1.20nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM271118(US10071086, Compound 382)
Affinity DataIC50:  3nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269257(US10071086, Compound 5)
Affinity DataIC50:  3.90nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM271120(US10071086, Compound 440)
Affinity DataIC50:  4nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269259(US10071086, Compound 7)
Affinity DataIC50:  6nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269254(US10071086, Compound 1)
Affinity DataIC50:  6nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269255(US10071086, Compound 2)
Affinity DataIC50:  6nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270609(US10071086, Compound 158)
Affinity DataIC50:  8nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275757(US10071086, Compound 785)
Affinity DataIC50:  10nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270606(US10071086, Compound 114)
Affinity DataIC50:  11nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270617(US10071086, Compound 229)
Affinity DataIC50:  12nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275764(US10071086, Compound 888)
Affinity DataIC50:  12nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270451(US10071086, Compound 18)
Affinity DataIC50:  13nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275758(US10071086, Compound 793)
Affinity DataIC50:  16nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275761(US10071086, Compound 803)
Affinity DataIC50:  17nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275735(US10071086, Compound 605)
Affinity DataIC50:  18nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275734(US10071086, Compound 602)
Affinity DataIC50:  18nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275730(US10071086, Compound 590)
Affinity DataIC50:  20nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270306(US10071086, Compound 12)
Affinity DataIC50:  21nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270480(US10071086, Compound 24)
Affinity DataIC50:  21nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275503(US10071086, Compound 458)
Affinity DataIC50:  22nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275609(US10071086, Compound 552)
Affinity DataIC50:  22nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275754(US10071086, Compound 765)
Affinity DataIC50:  27nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275740(US10071086, Compound 643)
Affinity DataIC50:  30nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270471(US10071086, Compound 22)
Affinity DataIC50:  32nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275759(US10071086, Compound 797)
Affinity DataIC50:  32nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275598(US10071086, Compound 551)
Affinity DataIC50:  33nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275738(US10071086, Compound 635)
Affinity DataIC50:  34nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275737(US10071086, Compound 621)
Affinity DataIC50:  36nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM269255(US10071086, Compound 2)
Affinity DataIC50:  38nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275749(US10071086, Compound 728)
Affinity DataIC50:  39nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275752(US10071086, Compound 758)
Affinity DataIC50:  48nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275495(US10071086, Compound 452)
Affinity DataIC50:  48nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275666(US10071086, Compound 581)
Affinity DataIC50:  48nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275762(US10071086, Compound 818)
Affinity DataIC50:  50nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM271093(US10071086, Compound 376)
Affinity DataIC50:  51nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275659(US10071086, Compound 557)
Affinity DataIC50:  53nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270853(US10071086, Compound 346)
Affinity DataIC50:  56nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270854(US10071086, Compound 352)
Affinity DataIC50:  57nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270830(US10071086, Compound 325)
Affinity DataIC50:  58nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM275763(US10071086, Compound 827)
Affinity DataIC50:  63nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenomatous polyposis coli protein(Homo sapiens (Human))
Samumed

US Patent
LigandPNGBDBM270999(US10071086, Compound 373)
Affinity DataIC50:  70nMAssay Description:Reporter cell lines can be generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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