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Found 20 Enz. Inhib. hit(s) with Target = 'DNA primase'
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034949(2-Amino-6-(3,5-dichloro-phenylamino)-3H-pyrimidin-...)
Affinity DataIC50:  770nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(CHEMBL53605 | N*2*-(3,4-Dichloro-phenyl)-9H-purine...)
Affinity DataIC50:  850nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034950(2-Amino-6-(3,4-dichloro-phenylamino)-3H-pyrimidin-...)
Affinity DataIC50:  850nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(2-(3,4-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...)
Affinity DataIC50:  880nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034947(2-(3,5-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...)
Affinity DataIC50:  910nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034963(CHEMBL51501 | N*2*-(3,5-Dichloro-phenyl)-9H-purine...)
Affinity DataIC50:  920nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034952(6-(3,5-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50028342(6-(3,4-Dichloro-phenylamino)-1H-pyrimidine-2,4-dio...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition against DNA-Dependent GTPase activity of HSV-1 helicase-primase in HSV-1-infected CV-1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Bacillus anthracis (Firmicutes))
University Of Michigan

LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  4.40E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Bacillus anthracis (Firmicutes))
University Of Michigan

LigandPNGBDBM50364890(Amixin IC | TILORONE | cid_5475)
Affinity DataIC50:  7.10E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Bacillus anthracis (Firmicutes))
University Of Michigan

LigandPNGBDBM50336799(5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino...)
Affinity DataIC50:  8.20E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034961(6-Chloro-N*4*-(3,4-dichloro-phenyl)-pyrimidine-2,4...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Mycobacterium tuberculosis)
University Of Michigan

LigandPNGBDBM22984((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...)
Affinity DataIC50:  9.30E+3nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50034955(CHEMBL53605 | N*2*-(3,4-Dichloro-phenyl)-9H-purine...)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50013091(2-(3,4-Dichloro-phenylamino)-1,9-dihydro-purin-6-o...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition against Primase by coupled primase-DNA polymerase-I assay with the two subunit recombinant HSV-1 helicase primaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Mycobacterium tuberculosis)
University Of Michigan

LigandPNGBDBM50364890(Amixin IC | TILORONE | cid_5475)
Affinity DataIC50:  6.90E+4nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Bacillus anthracis (Firmicutes))
University Of Michigan

LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  7.50E+4nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Human herpesvirus 1 (strain 17) (HHV-1) (Human her...)
Stanford University Medical School

Curated by ChEMBL
LigandPNGBDBM50137912((Biphenyl-4-sulfinyl)-acetic acid | (Biphenyl-4-su...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibitory concentration against herpes simplex virus helicase primase 8 (HSV)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase(Bacillus anthracis (Firmicutes))
University Of Michigan

LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataIC50: >1.00E+5nMpH: 8.8Assay Description:The reaction mixture contained DNA (1.25 uM or as specified), NTP (110 uM or as specified), 50 mM NaCl, 150 mM potassium glutamate, buffer [20 mM CAP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA primase TraC(Escherichia coli)
University Of Nebraska-Lincoln

Curated by ChEMBL
LigandPNGBDBM15236(3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)-4H-chr...)
Affinity DataIC50:  7.00E+5nMAssay Description:Inhibition of Escherichia coli primaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed