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Found 10 Enz. Inhib. hit(s) with Target = 'Genome polyprotein [1394-1440]/[1476-1660]'
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33256(phthalazine-based compound, 7)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33259(Bz-NKRR-H | Bz-Nle-Lys-Arg-Arg-H | CHEMBL256877)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33251(phthalazine-based compound, 2)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33254(phthalazine-based compound, 5)
Affinity DataIC50:  8.20E+3nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33252(phthalazine-based compound, 3)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33257(phthalazine-based compound, 8)
Affinity DataIC50:  1.98E+4nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33250(phthalazine-based compound, 1)
Affinity DataIC50:  3.28E+4nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33255(phthalazine-based compound, 6)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33253(phthalazine-based compound, 4)
Affinity DataIC50:  6.48E+4nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein [1394-1440]/[1476-1660](Dengue virus 4 (H241))
Novartis Institute For Tropical Diseases

LigandPNGBDBM33258(phthalazine-based compound, 9)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitors were assayed in a 96-well plate format. Typically, protease was preincubated with concentrations of test compounds at 37 deg C for 30 min....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed