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Found 22 Enz. Inhib. hit(s) with Target = 'Dihydroorotase'
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  7.60E+7nMpH: 7.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  2.10E+8nMpH: 8.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Escherichia coli)
Texas A&M University

LigandPNGBDBM85254(4,6-dioxo-piperidine-2-carboxylic acid, 3)
Affinity DataKi:  4.40E+8nMpH: 9.0Assay Description:The DHO-catalyzed hydrolysis of dihydrooroate was monitored spectrophotoetrically at 230 and 280 nm using a SPECTRAmax (Molecular Device) plate reade...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM154573(8-(trifluoromethyl)-9H-purin-6-amine (4) | acs.jme...)
Affinity DataIC50: >1.00E+5nMpH: 7.5Assay Description:The fluorogenic substrate used in this study was ubiquitin-AMC (Boston Biochem). All assays were performed in 384-well black plates (Corning) in a to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50007789(CHEMBL1173044 | GRL-0667 | N-(2H-1,3-benzodioxol-5...)
Affinity DataIC50: >1.00E+5nMpH: 7.5Assay Description:The fluorogenic substrate used in this study was ubiquitin-AMC (Boston Biochem). All assays were performed in 384-well black plates (Corning) in a to...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536772(CHEMBL1604422)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536771(CHEMBL1518262)
Affinity DataKd:  2.81E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536774(CHEMBL4560356)
Affinity DataKd: >1.00E+6nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50495373(CHEMBL3110262)
Affinity DataKd:  2.15E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536775(CHEMBL4572519)
Affinity DataKd:  3.80E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536775(CHEMBL4572519)
Affinity DataKd:  3.14E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536774(CHEMBL4560356)
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50136492(6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline | 6...)
Affinity DataKd:  6.75E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50136492(6-Methoxy-2,3,4,9-tetrahydro-1H-beta-carboline | 6...)
Affinity DataKd:  5.88E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536776(CHEMBL4580574)
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536769(CHEMBL4574809)
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536773(CHEMBL4532317)
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536772(CHEMBL1604422)
Affinity DataKd:  1.70E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536771(CHEMBL1518262)
Affinity DataKd:  1.57E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536770(CHEMBL4580389)
Affinity DataKd:  6.70E+4nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50536769(CHEMBL4574809)
Affinity DataKd:  1.44E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells in presence of N-carbamyl-L-aspart...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotase(Bacillus anthracis (Firmicute))
University Of Illinois At Chicago

LigandPNGBDBM50495373(CHEMBL3110262)
Affinity DataKd:  2.05E+5nMAssay Description:Binding affinity to Bacillus anthracis Sterne His-tagged DHOase expressed in Escherichia coli BL21(DE3) Gold cells by surface plasmon resonance analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed