TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: >8.95E+3nMAssay Description:Inhibition of CLK4More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataKi: <1.00E+5nMAssay Description:Inhibition of His/GST-tagged CLK4 (unknown origin) using biotinylated peptide as substrate measured after 1 hr in presence of [gamma-33P]-ATP by fluo...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of CLK4 (unknown origin) by Z'-LYTE assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Inhibition of recombinant GST-tagged mouse CLK4 using GRSRSRSRSRSR as substrate after 30 mins in presence of [gamma-32P]-ATP by scintillation countin...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 6.60nMAssay Description:Inhibition of human recombinant GST tagged full length CLK4 expressed in Baculovirus expression system at 1 uMMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human CLK4 expressed in baculovirus infected Sf21 cellsMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant full length N-terminal GST-tagged human CLK4 (128 end residues) expressed in baculovirus infected Sf21 insect cellsMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of human CLK4 (146 to 480 residues) expressed in Escherichia coli BL21 (DE3) Turner using MBP as substrate incubated for 60 mins in presen...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human CLK4 by radiometric assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant CLK4 using YRRAAVPPSPSLS substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 12nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant Clk4 (128 to end residues) using YRRAAVPPSPSLS peptide as substrate incubated for 40 mins in presence of [gamma 32P-A...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of CLK4 (unknown origin) assessed as reduction in SRSF10 phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse glutathione S-transferase-tagged Clk4 expressed in Escherichia coli DH5alpha using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH peptide a...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse Clk4Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged mouse CLK4 expressed in Escherichia coli using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH as substrate after 10 mins in presence o...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of GST-tagged recombinant mouse CLK4 expressed in Escherichia coli using RSPSYGRSRSRSRSRSRSRSRSNSRSRSY as substrate in presence of [gamma-...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of mouse recombinant GST-tagged CLK4 expressed in Escherichia coli DH5[alpha] using NH2-RSPSYGRSRSRSRSRSRSRSRSNSRSRSY-OH as substrate by l...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant CLK4 using YRRAAVPPSPSLS substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human CLK4 (128 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant CLK4 using YRRAAVPPSPSLS substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of full length recombinant human GST-tagged CLK4 expressed in baculovirus expression system by lantha screen kinase binding assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of CLK4 (unknown origin)More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant CLK4 using YRRAAVPPSPSLS substrate by radiometric scintillation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of CLK4 (unknown origin) by bioluminescence assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human CLK4 (128 to end residues) using YRRAAVPPSPSLSRHSSPHQS(p)EDEEE as substrate incubated for 40 mins in presence of [gam...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assayMore data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
TargetDual specificity protein kinase CLK4(Homo sapiens (Human))
Abbott Laboratories
Curated by ChEMBL
Abbott Laboratories
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of GST-tagged human recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of GST-fused mouse recombinant CLK4 expressed in Escherichia coli using GRSRSRSRSRSR peptide as substrate incubated for 30 mins in presenc...More data for this Ligand-Target Pair