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Found 244 Enz. Inhib. hit(s) with Target = 'G protein-activated inward rectifier potassium channel 4'
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50505262(CHEMBL4559408)
Affinity DataKi:  8.20nMAssay Description:Inhibition GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347074(US10202390, Example 29)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347063(US10202390, Example 18)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347062(US10202390, Example 17)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347061(3-(4-(isopropylamino)-5-(1-(tetrahydro-2H-pyran-4-...)
Affinity DataIC50:  2nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347064(US10202390, Example 19)
Affinity DataIC50:  3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347072(3-(5-(1-(3-hydroxy-3-methylbutyl)-1H-pyrazol-4-yl)...)
Affinity DataIC50:  3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347058(US10202390, Example 13)
Affinity DataIC50:  3nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347067(US10202390, Example 22)
Affinity DataIC50:  4nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347070(US10202390, Example 25)
Affinity DataIC50:  5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347073(US10202390, Example 28)
Affinity DataIC50:  5nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347060(3-(4-(isopropylamino)-5-(4-propyl-1H-1,2,3-triazol...)
Affinity DataIC50:  6nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347056(2-(6-chloropyrazolo[1,5-a]pyrimidin-3-yl)-N-isopro...)
Affinity DataIC50:  8nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347068(US10202390, Example 23)
Affinity DataIC50:  9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347057(US10202390, Example 12)
Affinity DataIC50:  9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347059(US10202390, Example 14)
Affinity DataIC50:  9nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347071(US10202390, Example 26)
Affinity DataIC50:  10nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347065(US10202390, Example 20)
Affinity DataIC50:  12nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347066(US10202390, Example 21)
Affinity DataIC50:  14nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347048(US10202390, Example 3)
Affinity DataIC50:  14nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347069(US10202390, Example 24)
Affinity DataIC50:  14nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347051(US10202390, Example 6)
Affinity DataIC50:  18nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347055(US10202390, Example 10)
Affinity DataIC50:  20nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347054(US10202390, Example 9)
Affinity DataIC50:  29nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347052(US10202390, Example 7 | US10202390, Example 8)
Affinity DataIC50:  43nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347052(US10202390, Example 7 | US10202390, Example 8)
Affinity DataIC50:  53nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347047(2-(7-chloroimidazo[1,2-b]pyridazin-3-yl)-N-isoprop...)
Affinity DataIC50:  63nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347050(US10202390, Example 5)
Affinity DataIC50:  174nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437954(CHEMBL2409269)
Affinity DataIC50:  180nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50497417(CHEMBL3339101)
Affinity DataIC50:  200nMAssay Description:Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437953(CHEMBL2409098)
Affinity DataIC50:  250nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437955(CHEMBL2409135)
Affinity DataIC50:  250nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437990(CHEMBL2409099)
Affinity DataIC50:  270nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437989(CHEMBL2409100)
Affinity DataIC50:  310nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437988(CHEMBL2409101)
Affinity DataIC50:  340nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347049(US10202390, Example 4)
Affinity DataIC50:  396nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437987(CHEMBL2409102)
Affinity DataIC50:  480nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50497404(CHEMBL3339117)
Affinity DataIC50:  550nMAssay Description:Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437952(CHEMBL2409118)
Affinity DataIC50:  560nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM347046(3-(5-(4-(2-hydroxypropan-2-yl)-1H-pyrazol-1-yl)-4-...)
Affinity DataIC50:  578nMAssay Description:TBDMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50497381(CHEMBL3339113)
Affinity DataIC50:  590nMAssay Description:Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437984(CHEMBL2409105)
Affinity DataIC50:  610nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50497373(CHEMBL3339115)
Affinity DataIC50:  640nMAssay Description:Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437986(CHEMBL2409103)
Affinity DataIC50:  690nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437985(CHEMBL2409104)
Affinity DataIC50:  720nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437958(CHEMBL2409124)
Affinity DataIC50:  780nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50437957(CHEMBL2409125)
Affinity DataIC50:  850nMAssay Description:Inhibition of GIRK1/4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50497416(CHEMBL3339118)
Affinity DataIC50:  850nMAssay Description:Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50497370(CHEMBL3339114)
Affinity DataIC50:  930nMAssay Description:Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetG protein-activated inward rectifier potassium channel 4(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50497401(CHEMBL3339108)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of GIRK1/4 (unknown origin) by thallium-flux based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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