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Found 12 Enz. Inhib. hit(s) with Target = 'Homoisocitrate dehydrogenase'
TargetHomoisocitrate dehydrogenase, mitochondrial(Saccharomyces cerevisiae)
Tokyo Institute Of Technology

LigandPNGBDBM23215(Homoisocitrate thia analogue, 3 | trisodium (2S,3S...)
Affinity DataKi:  97nM ΔG°:  -41.5kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase, mitochondrial(Saccharomyces cerevisiae)
Tokyo Institute Of Technology

LigandPNGBDBM23213(Homoisocitrate oxa analogue, 2 | trisodium (2S,3R)...)
Affinity DataKi:  1.00E+4nM ΔG°:  -29.6kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase, mitochondrial(Saccharomyces cerevisiae)
Tokyo Institute Of Technology

LigandPNGBDBM23216(3-[(carboxymethyl)sulfanyl]-2-oxopropanoic acid | ...)
Affinity DataKi:  1.20E+4nM ΔG°:  -29.1kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase, mitochondrial(Saccharomyces cerevisiae)
Tokyo Institute Of Technology

LigandPNGBDBM23220((1R,2Z)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...)
Affinity DataKi:  7.20E+4nM ΔG°:  -24.5kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase(Deinococcus radiodurans)
Tokyo Institute Of Technology

LigandPNGBDBM23221((2S,3R)-2-ethenyl-3-hydroxybutanedioic acid | Viny...)
Affinity DataKi:  8.80E+4nM ΔG°:  -23.4kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase(Deinococcus radiodurans)
Tokyo Institute Of Technology

LigandPNGBDBM23220((1R,2Z)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...)
Affinity DataKi:  2.60E+5nM ΔG°:  -20.7kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase, mitochondrial(Saccharomyces cerevisiae)
Tokyo Institute Of Technology

LigandPNGBDBM23218((2R,3Z)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...)
Affinity DataKi:  5.10E+5nM ΔG°:  -19.5kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase, mitochondrial(Saccharomyces cerevisiae)
Tokyo Institute Of Technology

LigandPNGBDBM23219((1R,2E)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...)
Affinity DataKi:  7.90E+5nM ΔG°:  -18.4kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase, mitochondrial(Saccharomyces cerevisiae)
Tokyo Institute Of Technology

LigandPNGBDBM23217((2R,3E)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...)
Affinity DataKi:  1.40E+6nM ΔG°:  -16.9kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase(Deinococcus radiodurans)
Tokyo Institute Of Technology

LigandPNGBDBM23219((1R,2E)-1-hydroxypent-2-ene-1,2,5-tricarboxylic ac...)
Affinity DataKi:  3.10E+6nM ΔG°:  -14.5kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase(Deinococcus radiodurans)
Tokyo Institute Of Technology

LigandPNGBDBM23217((2R,3E)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...)
Affinity DataKi:  5.20E+6nM ΔG°:  -13.2kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHomoisocitrate dehydrogenase(Deinococcus radiodurans)
Tokyo Institute Of Technology

LigandPNGBDBM23218((2R,3Z)-2-hydroxy-3-(3-hydroxypropylidene)butanedi...)
Affinity DataKi:  1.53E+7nM ΔG°:  -10.5kJ/molepH: 7.8 T: 2°CAssay Description:Enzyme reaction was monitored by measuring the NADH absorption at 340 nm on a UV-Vis spectrometer. The formation of NADH was measured for 30 s. Data ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed