Compile Data Set for Download or QSAR
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Found 3 Enz. Inhib. hit(s) with Target = 'NF-kappa-B essential modulator'
TargetNF-kappa-B essential modulator(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50130248(CHEMBL79004 | N-(6-Chloro-9H-beta-carbolin-8-yl)-n...)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of GST-IkB phosphorylation by TNF-alpha stimulated HeLa cell lysate (IP-IKKgamma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNF-kappa-B essential modulator(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50587701(CHEMBL5180326)
Affinity DataKd:  80nMAssay Description:Binding affinity to full-length human NEMO (1 to 419 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNF-kappa-B essential modulator(Homo sapiens (Human))
Millennium Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50587700(CHEMBL5171411)
Affinity DataKd:  190nMAssay Description:Binding affinity to full-length human NEMO (1 to 419 residues) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed