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Found 18 Enz. Inhib. hit(s) with Target = 'Integrin alpha-M/beta-2'
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50462087(CHEMBL4243248)
Affinity DataIC50:  140nMAssay Description:Inhibition of C3bi-AP binding to CR3 derived from human PMNMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM75309((2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of C3bi-AP binding to CR3 derived from human PMNMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM75309((2Z)-3-ethyl-2-[(E)-3-(3-ethyl-1,3-benzothiazol-3-...)
Affinity DataIC50:  2.50E+3nMAssay Description:Antagonist activity at CR3 in carboxyfluorescein diacetate succiminidyl ester-labeled human PMN assessed as inhibition of TNF/PMA-stimulated adhesion...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50462087(CHEMBL4243248)
Affinity DataIC50:  2.50E+3nMAssay Description:Antagonist activity at CR3 in carboxyfluorescein diacetate succiminidyl ester-labeled human PMN assessed as inhibition of TNF/PMA-stimulated adhesion...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50055896(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Mac-1 integrin (alphaM-beta2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50055896(3-{2-[3-(4-Carbamimidoyl-phenyl)-4,5-dihydro-isoxa...)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of Mac-1 interaction with ICAMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378540(CHEMBL583892)
Affinity DataEC50:  1.86E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378541(CHEMBL570321)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378542(CHEMBL569154)
Affinity DataEC50:  4.09E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378543(CHEMBL571876)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378544(CHEMBL570061)
Affinity DataEC50:  3.56E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378539(CHEMBL570524)
Affinity DataEC50:  4.04E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378546(CHEMBL585139)
Affinity DataEC50:  2.23E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378547(CHEMBL569007)
Affinity DataEC50:  1.80E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378538(CHEMBL570523)
Affinity DataEC50:  1.05E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378537(CHEMBL584543)
Affinity DataEC50:  2.32E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378536(CHEMBL572115)
Affinity DataEC50:  1.36E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-M/beta-2(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50378545(CHEMBL585545)
Affinity DataEC50: >5.00E+4nMAssay Description:Agonist activity at CD11b/CD18 expressed in K562 cells assessed as increase in cell adhesion to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed