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Found 7 Enz. Inhib. hit(s) with Target = 'Interleukin-10'
TargetInterleukin-10(Homo sapiens (Human))
Broad Institute

LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataEC50:  220nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-10(Homo sapiens (Human))
Broad Institute

LigandPNGBDBM192713(HG-9-91-01 derivative, 2)
Affinity DataEC50:  3nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-10(Homo sapiens (Human))
Broad Institute

LigandPNGBDBM192714(US11725011, Compound YKL-05-95 | YKL-05-095 (3))
Affinity DataEC50:  11nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-10(Homo sapiens (Human))
Broad Institute

LigandPNGBDBM192718(HG-9-91-01 derivative, 7)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-10(Homo sapiens (Human))
Broad Institute

LigandPNGBDBM192716(US11725011, Compound YKL-05-99 | YKL-05-099 (5))
Affinity DataEC50:  460nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-10(Homo sapiens (Human))
Broad Institute

LigandPNGBDBM192717(HG-9-91-01 derivative, 6)
Affinity DataEC50: >1.00E+4nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-10(Homo sapiens (Human))
Broad Institute

LigandPNGBDBM192715(US11725011, Compound YKL-05-96 | YKL-05-096 (4))
Affinity DataEC50:  70nMAssay Description:Concentration-dependent effects of HG-9-91-01 analogs on IL-10 release and cellular cytotoxicity in Zymosan A-stimulated BMDCs were measured using Al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed