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Found 63 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L3'
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50326016(3-amino-2-benzoyl-6-oxo-6,7-dihydrothieno[2,3-b]py...)
Affinity DataKi:  1.00E+5nMAssay Description:Inhibition of UCHL3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50590283(CHEMBL5169766 | US20230303547, Reference Example D)
Affinity DataIC50: >10nMAssay Description:Inhibition of GST-tagged recombinant UCHL3 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50590284(CHEMBL5192316)
Affinity DataIC50: >10nMAssay Description:Inhibition of GST-tagged recombinant UCHL3 (unknown origin) using Ub-Lys-TAMRA as substrate incubated for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50:  50nMAssay Description:Inhibition of UCHL3 (unknown origin) assessed as reduction in RAD51 deubiquitination incubated for 4 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50594731(CHEMBL1241028)
Affinity DataIC50:  600nMAssay Description:Inhibition of recombinant human UCHL3 expressed in baculovirus infected Sf9 cells using ubiquitin-AMC as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53421(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Affinity DataIC50:  600nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM53421(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Affinity DataIC50:  600nMAssay Description:Inhibition of UCHL3 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50069764(CHEMBL3407501)
Affinity DataIC50:  2.16E+3nMAssay Description:Inhibition of UCHL3 (unknown origin) using ubiquitin-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50594730(CHEMBL5193983)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of UCHL3 (unknown origin) incubated for 20 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50538571(CHEMBL4635160)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50594729(CHEBI:27485 | CHEMBL1397260)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of UCHL3 (unknown origin) using Ub-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM65518(5-Chloro-1-[(2,5-dichlorophenyl)methyl]-1H-indole-...)
Affinity DataIC50:  1.41E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50442907(Acetyl Isogambogic Acid | CHEMBL3039433)
Affinity DataIC50:  1.54E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53469(MLS001209351 | N-[1-(4-Bromo-phenyl)-ethylidene]-N...)
Affinity DataIC50:  1.60E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53467(1,3-Dimethyl-5-nitro-6-[2-(4-propoxy-phenyl)-vinyl...)
Affinity DataIC50:  1.70E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50326012(3-(acetoxyimino)-5-bromo-1-(3,4-dichlorobenzyl)ind...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of UCHL3 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53470(2-N,2-N,4-N,4-N-tetraethyl-6-N-(4-nitrophenyl)-1,3...)
Affinity DataIC50:  1.80E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53443(2-(3-chloro-4-methoxy-N-methylsulfonylanilino)-N-[...)
Affinity DataIC50:  2.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53468(2-[3-cyano-4-(2-methoxyphenyl)-6-phenyl-pyridin-2-...)
Affinity DataIC50:  2.30E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50326014(3-(acetoxyimino)-1-(3,4-dichlorobenzyl)-5-iodoindo...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of UCHL3 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53416((2S)-2-[[4-[(4-chlorophenyl)carbamoyl]-1H-imidazol...)
Affinity DataIC50:  2.40E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM200235(Rifampicin | cid_5381226)
Affinity DataIC50:  2.48E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53442((7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-ox...)
Affinity DataIC50:  2.50E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53441(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Affinity DataIC50:  2.50E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50594733(CHEMBL4303698)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of UCHL3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50326013(3-(acetoxyimino)-5-bromo-1-(2,5-dichlorobenzyl)ind...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of UCHL3 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53449(4-(4-bromophenyl)-2-(o-toluoylamino)-3-thenoic aci...)
Affinity DataIC50:  3.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53413((2S)-2-[[[4-[(4-methylanilino)-oxomethyl]-1H-imida...)
Affinity DataIC50:  3.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM205457((2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9...)
Affinity DataIC50:  3.21E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53414((2S)-4-methyl-2-[[4-(m-tolylcarbamoyl)-1H-imidazol...)
Affinity DataIC50:  3.30E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53445(2-(4-hydroxy-3-nitro-benzylidene)-3-keto-5-(2-meth...)
Affinity DataIC50:  4.00E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53482(1-Butyl-4-hydroxy-2-oxo-1,2-dihydro-quinoline-3-ca...)
Affinity DataIC50:  4.10E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50326015(5-(4-butylphenyl)-4-(4-isopropylphenyl)-4H-1,2,4-t...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of UCHL3 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50594732(CHEMBL5195092)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of recombinant human UCHL3 expressed in baculovirus infected Sf9 cells using ubiquitin-AMC as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53422(2,4-Dicyclohexyl-6-methoxy-quinazoline | 2,4-dicyc...)
Affinity DataIC50:  4.70E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53447(4,4'-[1,4-phenylenebis(oxy)]diphenol | 4-[4-(4...)
Affinity DataIC50:  4.70E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53419((2S)-2-[[4-[(4-methoxyphenyl)carbamoyl]-1H-imidazo...)
Affinity DataIC50:  4.80E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53415((2S)-2-[[4-(m-tolylcarbamoyl)-1H-imidazole-5-carbo...)
Affinity DataIC50:  5.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53454((2E)-2-[(2Z)-2-(3-methoxy-4-oxidanylidene-cyclohex...)
Affinity DataIC50:  5.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50242207(CHEMBL455364 | Mangiferin)
Affinity DataIC50:  5.26E+4nMpH: 7.5 T: 2°CAssay Description:Ubiquitin-7-amino-4-methylcoumarin (Ub-AMC) was generated as previously described.(7) The enzymatic reaction was conducted in fluorometric assay buff...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53418((2S)-2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imida...)
Affinity DataIC50:  5.80E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  7.10E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of UCHL3 in human H1299 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM24778(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of recombinant human UCHL3 expressed in baculovirus infected Sf9 cells using ubiquitin-AMC as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53471((3-Ethyl-5-hydroxy-5-phenyl-4,5-dihydro-pyrazol-1-...)
Affinity DataIC50:  7.20E+4nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50552483(CHEMBL4763594)
Affinity DataIC50:  7.40E+4nMAssay Description:Inhibition of recombinant human UCHL3 assessed as reduction in cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine110-glycine using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50270667(CHEMBL4130194)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM50538549(CHEMBL4641424)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human GST-tagged UCHL3 expressed in Escherichia coli assessed as cleavage of Ubiquitin-Rhodamine110-glycine to Ubiquitin and Rhodamine1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Homo sapiens (Human))
Institute For Bio-Medical Research

Curated by ChEMBL
LigandPNGBDBM23421(1-benzyl-3-hydroxy-4-[(5-methylfuran-2-yl)carbonyl...)
Affinity DataIC50:  1.03E+5nMpH: 7.8 T: 2°CAssay Description:Enzyme reactions were carried out on Costar 96-well black assay plates. After the reaction, AMC fluorescence (excitation wavelength: 355 nm, emission...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L3(Mus musculus (Mouse))
Brigham And Women'S Hospital

LigandPNGBDBM53448(1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidi...)
Affinity DataIC50:  1.13E+5nMpH: 7.6 T: 2°CAssay Description:Inhibition activity and selectivity for UCH-L1 and UCH-L3.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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