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Found 96 Enz. Inhib. hit(s) with Target = 'Uracil-DNA glycosylase'
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM36456(6-[3-(Aminooxypropylamino)methyl]uracil, dihydroch...)
Affinity DataKi:  7.00E+5nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM36457(3-[(3-Aminopropoxyimino)methyl]uracil, hydrochlori...)
Affinity DataKi:  7.50E+5nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208055(3-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...)
Affinity DataIC50:  42nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208056(2-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...)
Affinity DataIC50:  46nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208057( 4-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol...)
Affinity DataIC50:  208nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208058(3-(3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indol-...)
Affinity DataIC50:  244nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM36453(6-[3-[(3-Carboxy-benzylidene)aminooxypropylamino]-...)
Affinity DataIC50:  1.30E+3nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
TargetUracil-DNA glycosylase(Vaccinia virus (strain Western Reserve) (VACV) (Va...)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM33154(4-[(2-benzoxybenzyl)amino]phenol | 4-[(2-phenylmet...)
Affinity DataIC50:  5.10E+3nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208048( 3-((3,5-Dichlorophenyl)thio)-6-methyl-1H-indole-2...)
Affinity DataIC50:  7.00E+3nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078333(6-(4-Octyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibitory potency of the compound against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208049(3-((3,5-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...)
Affinity DataIC50:  9.00E+3nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078341(1-(2-Hydroxy-ethyl)-6-(4-octyl-phenylamino)-1H-pyr...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208051(6-Methyl-3-(phenylthio)-1H-indole-2-carboxylate |...)
Affinity DataIC50:  1.00E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078334(1-(2-Methoxy-ethyl)-6-(4-octyl-phenylamino)-1H-pyr...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208054(4-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...)
Affinity DataIC50:  1.80E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208038(Methyl 3-((4-chlorophenyl)thio)-6-methyl-1H-indole...)
Affinity DataIC50:  1.90E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078336(6-(4-Hexyl-phenylamino)-1-(2-hydroxy-ethyl)-1H-pyr...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208040(Methyl 3-((4-chlorophenyl)thio)-4-methyl-1H-indole...)
Affinity DataIC50:  2.10E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208053(7-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...)
Affinity DataIC50:  2.10E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208039(Methyl 3-((4-chlorophenyl)thio)-7-methyl-1H-indole...)
Affinity DataIC50:  2.30E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208052(6-Methyl-3-((2,4,5-trichlorophenyl)thio)-1H-indole...)
Affinity DataIC50:  2.50E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078338(6-(4-Octyloxy-phenylamino)-1H-pyrimidine-2,4-dione...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078339(6-(4-Hexyloxy-phenylamino)-1H-pyrimidine-2,4-dione...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078340(6-(4-Hexyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208043(6-Methyl-3-((4-(trifluoromethyl)phenyl)thio)-1H-in...)
Affinity DataIC50:  3.30E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208045(3-((3,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...)
Affinity DataIC50:  3.40E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Western Reserve) (VACV) (Va...)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50343395(10-(cyclohexylamino)-12-[(2-hydroxyethyl)amino]-15...)
Affinity DataIC50:  3.41E+4nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078335(6-(4-Decyl-phenylamino)-1H-pyrimidine-2,4-dione | ...)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 Uracil-DNA glycosylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208046(3-((3,4-Dichlorophenyl)thio)-7-methyl-1H-indole-2-...)
Affinity DataIC50:  3.50E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208032(3-((4-Chlorophenyl)thio)-6-ethyl-1H-indole-2-carbo...)
Affinity DataIC50:  3.60E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208044(3-((2,4-Dichlorophenyl)thio)-6-methyl-1H-indole-2-...)
Affinity DataIC50:  3.70E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Western Reserve) (VACV) (Va...)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM80984(4-chloranyl-2-(5-chloranyl-2-oxidanyl-phenyl)sulfa...)
Affinity DataIC50:  3.85E+4nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208037(Methyl 3-((4-chlorophenyl)thio)-1-ethyl-5-methyl-1...)
Affinity DataIC50:  3.90E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM36452(6-[[(3-Carboxy-benzylidene)-aminooxy]ethoxyimino]m...)
Affinity DataIC50:  4.00E+4nMpH: 8.0Assay Description:Inhibition of human uracil DNA glycosylase using high-throughput fluorescent molecular beacon DNA substrate.More data for this Ligand-Target Pair
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208031(6-Fluoro-3-((4-chlorophenyl)thio)-1H-indole-2-carb...)
Affinity DataIC50:  4.00E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208047(3-((3,4-Dichlorophenyl)thio)-6-ethyl-1H-indole-2-c...)
Affinity DataIC50:  4.20E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208050(3-((3,5-Dichlorophenyl)thio)-1H-indole-2-carboxyli...)
Affinity DataIC50:  4.30E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208027(3-((4-Chlorophenyl)thio)-5-methyl-1H-indole-2-carb...)
Affinity DataIC50:  4.60E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208029(6-Chloro-3-((4-chlorophenyl)thio)-1H-indole-2-carb...)
Affinity DataIC50:  4.70E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208033( 3-((4-chlorophenyl)thio)-4,7-dimethyl-1H-indole-2...)
Affinity DataIC50:  5.00E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208030( 6-Bromo-3-((4-chlorophenyl)thio)-1H-indole-2-carb...)
Affinity DataIC50:  5.10E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208041(3-((3-Chlorophenyl)thio)-6-methyl-1H-indole-2-carb...)
Affinity DataIC50:  5.10E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208042(3-((3-Fluorophenyl)thio)-6-methyl-1H-indole-2-carb...)
Affinity DataIC50:  6.90E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208028(3-((4-Chlorophenyl)thio)-7-methyl-1H-indole-2-carb...)
Affinity DataIC50:  7.40E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM196157(US9211296, Table 6, 11 | US9233921, 1)
Affinity DataIC50:  8.20E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208035(3-((4-Chlorophenyl)thio)-1-ethyl-5-methyl-1H-indol...)
Affinity DataIC50:  8.60E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Vaccinia virus (strain Copenhagen) (VACV))
University Of Pennsylvania

US Patent
LigandPNGBDBM208026(3-((4-Chlorophenyl)thio)-4-methyl-1H-indole-2-carb...)
Affinity DataIC50:  8.60E+4nMT: 2°CAssay Description:African green monkey kidney BSC-1 cells were grown in Dulbecco's modified Eagle medium (DMEM) supplemented with 10% fetal bovine serum (FBS) (Gibco B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078342(6-(4-Hexyl-phenylamino)-1-(3-hydroxy-propyl)-1H-py...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Vaccinia virus (strain Western Reserve) (VACV) (Va...)
University Of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50343412(4-[5-(4-bromophenyl)-4-phenyl-1H-imidazol-2-yl]-2,...)
Affinity DataIC50:  9.12E+4nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUracil-DNA glycosylase(Homo sapiens (Human))
Johns Hopkins University

LigandPNGBDBM50078343(6-(4-Hexyl-phenylamino)-1-(3-methoxy-propyl)-1H-py...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory potency of the compound against HSV-1 UDG (Herpes Simplex virus type-I Uracil DNA glycosylase)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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