Compile Data Set for Download or QSAR
maximum 50k data
Found 199 Enz. Inhib. hit(s) with Target = 'dCTP pyrophosphatase 1'
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM85128(Triptriolide, 5)
Affinity DataKi:  8.50E+4nM ΔG°:  -23.2kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM85127(Triptonide, 4)
Affinity DataKi:  1.35E+5nM ΔG°:  -22.1kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50241049(CHEMBL463763 | Triptolide, 1 | triptolide)
Affinity DataKi:  1.68E+5nM ΔG°:  -21.5kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo...More data for this Ligand-Target Pair
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM85130(14-alpha-triptolide, 7)
Affinity DataKi:  1.94E+5nM ΔG°:  -21.2kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM85129(5-Hydroxytriptonide, 6)
Affinity DataKi:  3.56E+5nM ΔG°:  -19.7kJ/molepH: 7.4 T: 2°CAssay Description:Kinetic enzyme assays were performed in a 384-well, white plates (Nunc) on a Wallac Victor 2 plate reader using human DCTPP1 and triptolide and analo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150038(CHEMBL3771346)
Affinity DataIC50:  19nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM38321(6-(3,4-dimethoxyphenyl)-3-(2-furanyl)-[1,2,4]triaz...)
Affinity DataIC50:  19nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239529(CHEMBL4072033)
Affinity DataIC50:  19nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50:  20nMAssay Description:Inhibition of human dCTPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236118(CHEMBL4065181)
Affinity DataIC50:  20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150044(CHEMBL3771039)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239517(CHEMBL4082508)
Affinity DataIC50:  25nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150112(CHEMBL3769835)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150043(CHEMBL3769727)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239516(CHEMBL4060634)
Affinity DataIC50:  34nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239518(CHEMBL4075978)
Affinity DataIC50:  36nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239518(CHEMBL4075978)
Affinity DataIC50:  36nMAssay Description:Inhibition of human dCTPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239530(CHEMBL4101470)
Affinity DataIC50:  38nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239519(CHEMBL4091797)
Affinity DataIC50:  41nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150036(CHEMBL3771227)
Affinity DataIC50:  41nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150051(CHEMBL3770446)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150040(CHEMBL3771237)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150052(CHEMBL3771105)
Affinity DataIC50:  47nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150052(CHEMBL3771105)
Affinity DataIC50:  47nMAssay Description:Inhibition of human dCTPase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150035(CHEMBL3769687)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239514(CHEMBL4098065)
Affinity DataIC50:  51nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150026(CHEMBL3771138)
Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239515(CHEMBL4061657)
Affinity DataIC50:  65nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150039(CHEMBL3769653)
Affinity DataIC50:  73nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150114(CHEMBL3770789)
Affinity DataIC50:  74nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150049(CHEMBL3770659)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM38325(6-(3,4-dimethoxyphenyl)-3-(2-pyridinyl)-[1,2,4]tri...)
Affinity DataIC50:  79nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150050(CHEMBL3770096)
Affinity DataIC50:  82nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150053(CHEMBL3770930)
Affinity DataIC50:  85nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150041(CHEMBL3770808)
Affinity DataIC50:  95nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236105(CHEMBL4065981)
Affinity DataIC50:  95nMAssay Description:Inhibition of recombinant human N-terminal His-tagged dCTPase 1 expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150115(CHEMBL3770403)
Affinity DataIC50:  96nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150042(CHEMBL3770193)
Affinity DataIC50:  133nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236122(CHEMBL4078660)
Affinity DataIC50:  144nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236110(CHEMBL4086793)
Affinity DataIC50:  164nMAssay Description:Inhibition of recombinant human N-terminal His-tagged dCTPase 1 expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150037(CHEMBL3770701)
Affinity DataIC50:  165nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236124(CHEMBL4086506)
Affinity DataIC50:  170nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50239511(CHEMBL4065129)
Affinity DataIC50:  170nMAssay Description:Inhibition of human full length N-terminal His-tagged dCTPase expressed in Escherichia coli BL21(DE3) using dCTP as substrate by HTS-based malachite ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236128(CHEMBL4065061)
Affinity DataIC50:  177nMAssay Description:Inhibition of recombinant human N-terminal His-tagged dCTPase 1 expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150046(CHEMBL3770766)
Affinity DataIC50:  185nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236102(CHEMBL4095068)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant human N-terminal His-tagged dCTPase 1 expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50260234(CHEMBL4060941)
Affinity DataIC50:  190nMAssay Description:Inhibition of full-length recombinant human dCTPase at by microtiter plate-adapted malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50150047(CHEMBL3770307)
Affinity DataIC50:  190nMAssay Description:Inhibition of human recombinant full length dCTPase expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by HTS-adapted Ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50260217(CHEMBL4062129)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetdCTP pyrophosphatase 1(Homo sapiens (Human))
Yale University

LigandPNGBDBM50236111(CHEMBL4104690)
Affinity DataIC50:  204nMAssay Description:Inhibition of recombinant human N-terminal His-tagged dCTPase 1 expressed in Escherichia coli BL21(DE3)pLysS using dCTP as substrate after 1 hr by ma...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 199 total ) | Next | Last >>
Jump to: