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Found 941 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase type 2'
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50210884(1-(1-(3-methoxy-4-methylbenzoyl)piperidin-4-yl)-1H...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 11betaHSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50317206((3-Phenyl-adamantan-1-yl)-piperidin-1-yl-methanone...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of 11-beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50216917(2-(cyclooctylamino)-5,5-diethyloxazol-4(5H)-one | ...)
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Rattus norvegicus)
University Of Bath

Curated by ChEMBL
LigandPNGBDBM50147505((2S,4aS,6aS,6bR,10S,12aS,14bR)-10-Hydroxy-2,4a,6a,...)
Affinity DataIC50:  0.00400nMAssay Description:Percent inhibition against 11-beta-hydroxysteroid dehydrogenase 2 of wistar rat kidney at 10 microM was determined using [3H]-cortisolMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50359991(CHEMBL1927953)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone into [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50359991(CHEMBL1927953)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human 11beta-HSD2 expressed in human HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximity as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50185127((3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human 11beta-HSD2 overexpressed in microsomal fraction of HEK293 cells using [3H]-cortisol as substrate by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50233538(18beta-glycyrrhetic acid | 3beta-hydroxy-11-oxoole...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of full-length human 11beta-HSD2 expressed in HEK293 microsomal fraction using [3H]cortisone as substrate after 2 hr by scintillation prox...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50329192((3beta,18beta,20beta)-3-Acetoxy-N-methyl-N-hydroxy...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50174298(3-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)bicy...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human microsomal 11beta-HSD2 assessed as inhibition of conversion of radiolabeled cortisone to radiolabeled cortisol by cell-based assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50329187((3alpha,18beta,20beta)-3-Methoxyamino-11-oxo-olean...)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50340378(3-(4-(2-(ethylsulfonyl)ethyl)bicyclo[2.2.2]octan-1...)
Affinity DataIC50:  7.5nMAssay Description:Inhibition of human microsomal 11beta-HSD2 assessed as inhibition of conversion of radiolabeled cortisone to radiolabeled cortisol by cell-based assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50340431((4-(1H-imidazol-4-yl)piperidin-1-yl)(3,4-dihydroqu...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50306423(2-{1'-[(adamantan-2-yl)carbamoyl]-5-methyl-2,3-dih...)
Affinity DataIC50:  10nMAssay Description:Inhibition of 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50112133(CHEMBL3609861 | US9464044, 71)
Affinity DataIC50: >10nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50340432((4-(1H-imidazol-4-yl)piperidin-1-yl)(3-methyl-2H-b...)
Affinity DataIC50: >10nMAssay Description:Inhibition of human recombinant 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642875((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50:  10nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50339805((3beta,18beta,20beta)-[3-(1,2,4-Oxadiazole-5(2H)-o...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50339809((5aR,7aR,7bS,9aS,12S,13aR,15aR,15bS)-2,3,4,5,5a,6,...)
Affinity DataIC50:  11nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642880((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(Ben...)
Affinity DataIC50:  12.6nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50329188((3beta,18beta,20beta)-3-Methoxyamino-11-oxo-olean-...)
Affinity DataIC50:  14.5nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50339811((3beta,18beta,20beta)-N-Hydroxy-N-methyl-[3-(1,2,4...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50339812(CHEMBL1689283 | N-[(3beta,18beta,20beta)-3-Hydroxy...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642882((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-((Cy...)
Affinity DataIC50:  20nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50193790(6-((1-cycloheptyl-4,4-dimethyl-5-oxopyrrolidin-3-y...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human 11beta-HSD2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50435691(CHEMBL2391968)
Affinity DataIC50:  30nMAssay Description:Inhibition of human microsomal 11beta-HSD2 assessed as inhibition of conversion of radiolabeled cortisone to radiolabeled cortisol by cell-based assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50340386(3-(4-(ethylsulfonylmethyl)bicyclo[2.2.2]octan-1-yl...)
Affinity DataIC50:  31nMAssay Description:Inhibition of human microsomal 11beta-HSD2 assessed as inhibition of conversion of radiolabeled cortisone to radiolabeled cortisol by cell-based assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642889((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-acet...)
Affinity DataIC50:  31.6nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642894((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-Acet...)
Affinity DataIC50:  31.6nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50339808(CHEMBL1689279 | N-[(5aR,7aR,7bS,9aS,12S,13aR,15aR,...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50339813(CHEMBL1689284 | N-[(3beta,18beta,20beta)-3,11-Diox...)
Affinity DataIC50:  45nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50188387((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-10-amino-2...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant 11betaHSD2 transfected in intact HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50329193((3beta,18beta,20beta)-3-Acetoxy-N-hydroxy-11-oxo-o...)
Affinity DataIC50:  61.1nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642893((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-acet...)
Affinity DataIC50:  63.1nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642901((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[(2-...)
Affinity DataIC50:  63.1nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642892((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-(ace...)
Affinity DataIC50:  79.4nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Chinese Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50247012(3beta-O-Succinyl-18-beta-glycyrrhetinic acid | Car...)
Affinity DataIC50:  82nMAssay Description:Inhibition of mouse microsomal 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol by scintillation proximi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50277202(CHEMBL4174368)
Affinity DataIC50: <100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50277203(CHEMBL4170932)
Affinity DataIC50:  100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642877((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50:  100nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)
Affinity DataIC50: <100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50277179(CHEMBL4160328)
Affinity DataIC50:  100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50277198(CHEMBL4163698)
Affinity DataIC50: <100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50339806((3beta,18beta,20beta)-N-[-3-(Acetoxy)-11-oxo-30-no...)
Affinity DataIC50:  104nMAssay Description:Inhibition of human 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-[3H]cortisol to cortisone after 10 mins by scintillation...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM50329195((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)
Affinity DataIC50:  122nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as conversion of [1,2,6,7-3H]-cortisol to cortisone by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642909((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-2,4a,6a...)
Affinity DataIC50:  126nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Biovitrum

Curated by ChEMBL
LigandPNGBDBM642913((2S,4aS,6aS,6bR,8aR,9S,10S,12aS,12bR,14bR)-10-[4-(...)
Affinity DataIC50:  126nMAssay Description:Human descending colon epithelial stem cells were cultured as 3D organoids in accordance with Sato et al Gastroenterology. 2011 November; 141(5): 176...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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