Found 19 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7'
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5-HT receptor (unknown origin)More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Ability to displace [3H]5-HT binding from 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 2.24E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 4.07E+4nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 4.08E+4nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 1.51E+5nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 1.62E+5nMAssay Description:Inhibition of AA+phentolamine by the compound in response of SECMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 3.47E+5nMAssay Description:Inhibition of ADP by the compound in response of SECMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 6.61E+5nMAssay Description:Inhibition of Arachidonic acid by the compound in response of SECMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 8.13E+5nMAssay Description:Inhibition of U-46,619 + phentolamine by the compound in response of SECMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 9.33E+5nMAssay Description:Ability to displace [3H]5-HT binding from 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligandMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 1.55E+6nMAssay Description:Inhibition of U-46,619 by the compound in response of SECMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 2.29E+12nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 3.63E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 5.50E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataIC50: 6.46E+13nMAssay Description:Stimulatory activity against serotonin secretion (SEC).More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataKd: 8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataKd: 43nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A/1B/1D/1E/1F/2A/2B/2C/3A/3B/3C/3D/3E/4/5A/6/7(Homo sapiens (Human))
Abbott Healthcare Products
Curated by ChEMBL
Abbott Healthcare Products
Curated by ChEMBL
Affinity DataKd: 8.40E+3nMAssay Description:Ability to displace [3H]5-HT binding to 5-hydroxytryptamine receptor site using 1 uM LSD as masking ligand, activity is expressed as Kd.More data for this Ligand-Target Pair