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Found 7 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member B10 [K125R,V301L]'
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM200221(2-(5-chloro-2-(((perbromophenyl)methyl)carbamoyl)p...)
Affinity DataIC50:  80nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM200222(2-(2,4-dioxo-3-(2,3,4,5-tetrabromo-6-methoxybenzyl...)
Affinity DataIC50:  450nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM200220(2-(5-chloro-2-((2,4,6-tribromobenzyl)carbamoyl)phe...)
Affinity DataIC50:  1.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM50012899((Z)-5-Fluoro-2-methyl-1-((p-(methylsulfinyl)phenyl...)
Affinity DataIC50:  2.69E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM16238(2-(2-{[(4-bromo-2-fluorophenyl)methyl]carbamoyl}-5...)
Affinity DataIC50:  4.40E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM104022(MK319)
Affinity DataIC50:  7.00E+3nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member B10 [K125R,V301L](Homo sapiens (Human))
Institut De Ge??Ne??Tique Et De Biologie Mole??Culaire Et Cellulaire

LigandPNGBDBM104020(MK181)
Affinity DataIC50:  1.02E+4nMpH: 7.0Assay Description:The IC50-activity assays were carried out on the basis of the quantification of the NADPH consumption that takes place when the enzyme catalyzes the ...More data for this Ligand-Target Pair