TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 1nM ΔG°: -51.4kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 1.5nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 2.30nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 5nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II isoform); Range is 6-10 nMMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nM ΔG°: -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 7nM ΔG°: -46.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibitory activity of the compound against IMPDH II with respect to IMP and NADMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 8nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 10nM ΔG°: -45.7kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human IMPDH 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human IMP dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibition of human IMPDH2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 10nMAssay Description:Inhibitory activity against human Inosine-5'-monophosphate dehydrogenase 2 (IMPDH type II)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Un-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 14nM ΔG°: -44.8kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Non-competitive inhibition of Cryptosporidium IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 16nM ΔG°: -44.5kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 16nMAssay Description:Inhibition of Cryptosporidium parvum IMPDH expressed in Escherichia coli assessed as apparent inhibition constant using NAD as substrate by fluoresce...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before NAD+ substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 19nM ΔG°: -44.1kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human IMP dehydrogenase 1More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human IMPDH1 by SpectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Inhibition of human IMPDH1More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 1(Homo sapiens (Human))
University Of Minnesota
Curated by ChEMBL
University Of Minnesota
Curated by ChEMBL
Affinity DataKi: 20nM ΔG°: -43.9kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 1 (87 and 155 nM) and varying concentrations of ...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 21nMAssay Description:The compound was tested for the inhibition towards IMP(Inosine 5'-monophosphate) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase(Bacillus anthracis)
Brandeis University
Curated by ChEMBL
Brandeis University
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Non-competitive inhibition of Bacillus anthracis IMPDH preincubated for 10 mins before IMP substrate addition by spectrophotometryMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of IMPDH2 (unknown origin)More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 26nMAssay Description:The compound was tested for the inhibition towards NMD (Nicotinamide adenine dinucleotide) substrate of Inosine-5'-monophosphate dehydrogenase 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 27nM ΔG°: -43.2kJ/molepH: 8.0 T: 2°CAssay Description:Inhibition assays were performed in duplicate using two different concentrations of human IMPDH type 2 (33 and 66 nM) and varying concentrations of i...More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human IMPDH 2More data for this Ligand-Target Pair
TargetInosine-5'-monophosphate dehydrogenase 2(Homo sapiens (Human))
Codon Pharmaceuticals
Curated by ChEMBL
Codon Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of human IMPDH2 by SpectrophotometerMore data for this Ligand-Target Pair