Compile Data Set for Download or QSAR
maximum 50k data
Found 107 Enz. Inhib. hit(s) with Target = 'Glutamate receptor ionotropic, NMDA 2D'
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
University Of Copenhagen

LigandPNGBDBM213888(1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...)
Affinity DataKi: >300nM ΔG°: >-37.2kJ/mole IC50: >3.00E+3nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
University Of Copenhagen

LigandPNGBDBM213888(1-thioxo-1,2-dihydro-[1,2,4]triazolo[4,3-a]-quinox...)
Affinity DataIC50:  160nMpH: 7.4 T: 2°CAssay Description:Two-electrode voltage clamp (TEVC) recordings were performed on Xenopus oocytes at room temperature 3-6 days postinjection using an OC-725C TEVC ampl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440060(CHEMBL2426081)
Affinity DataIC50:  170nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440067(CHEMBL2426072 | CHEMBL2426073)
Affinity DataIC50:  190nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440084(CHEMBL2426093)
Affinity DataIC50:  290nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440065(CHEMBL2426075)
Affinity DataIC50:  320nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440085(CHEMBL2426092)
Affinity DataIC50:  390nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440057(CHEMBL2426097)
Affinity DataIC50:  440nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440081(CHEMBL2426096)
Affinity DataIC50:  510nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440077(CHEMBL2425977)
Affinity DataIC50:  530nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440067(CHEMBL2426072 | CHEMBL2426073)
Affinity DataIC50:  570nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440058(CHEMBL2426100)
Affinity DataIC50:  580nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440074(CHEMBL2426065)
Affinity DataIC50:  660nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440052(CHEMBL2426105)
Affinity DataIC50:  690nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440063(CHEMBL2426077)
Affinity DataIC50:  690nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440072(CHEMBL2426067)
Affinity DataIC50:  700nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440073(CHEMBL2426066)
Affinity DataIC50:  810nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440075(CHEMBL2425979)
Affinity DataIC50:  910nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50242447(CHEMBL525783)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436101(CHEMBL2397257 | US10273214, Example 1180-27)
Affinity DataIC50:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436102(CHEMBL2397256 | US10273214, Example 1180-26)
Affinity DataIC50:  1.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440051(CHEMBL2425972)
Affinity DataIC50:  1.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440076(CHEMBL2425978)
Affinity DataIC50:  1.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50242446(CHEMBL524338)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50242449(CHEMBL525025 | conantokin-G)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of rat NMDA NR2D receptor expressed in xenopus oocytes coexpressing NMDA NR13b assessed as effect on glycine-induced current response at -...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440062(CHEMBL2426078)
Affinity DataIC50:  1.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440091(CHEMBL2426086)
Affinity DataIC50:  1.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440070(CHEMBL2426068 | CHEMBL2426069)
Affinity DataIC50:  1.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50503153(CHEMBL4544421)
Affinity DataIC50:  1.40E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440078(CHEMBL2426101)
Affinity DataIC50:  1.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436090(CHEMBL2397119 | US10273214, Example 1180-31)
Affinity DataIC50:  1.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440061(CHEMBL2424674)
Affinity DataIC50:  1.70E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440050(CHEMBL2425973)
Affinity DataIC50:  1.90E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440059(CHEMBL2426082)
Affinity DataIC50:  1.90E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436082(CHEMBL2397103 | US10273214, Example 1391)
Affinity DataIC50:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436072(CHEMBL2397211 | US10273214, Example 1426)
Affinity DataIC50:  2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440055(CHEMBL2426102)
Affinity DataIC50:  2.30E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50503149(CHEMBL4464605)
Affinity DataIC50:  2.40E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440047(CHEMBL2425976)
Affinity DataIC50:  2.60E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50440056(CHEMBL2333944)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of NMDA GluN2D receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50503146(CHEMBL4447266)
Affinity DataIC50:  2.70E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50440056(CHEMBL2333944)
Affinity DataIC50:  2.70E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440053(CHEMBL2426104)
Affinity DataIC50:  2.80E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440083(CHEMBL2426094)
Affinity DataIC50:  2.90E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436060(CHEMBL2397100 | US10273214, Example 1390)
Affinity DataIC50:  3.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440092(CHEMBL2426085)
Affinity DataIC50:  3.10E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440080(CHEMBL2426098)
Affinity DataIC50:  3.40E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50324401((E)-4-(6-Methoxy-2-(3-nitrostyryl)-4-oxoquinazolin...)
Affinity DataIC50:  3.90E+3nMAssay Description:Negative allosteric modulation of GluN2D receptor (unknown origin) expressed in xenopus laevis oocytes assessed as reduction in glycine-induced chann...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2D(Homo sapiens (Human))
Emory University

US Patent
LigandPNGBDBM50436085(CHEMBL2397093 | US10273214, Example 1180-15)
Affinity DataIC50:  4.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails US Patent
TargetGlutamate receptor ionotropic, NMDA 2D(Rattus norvegicus (Rat))
Emory University

Curated by ChEMBL
LigandPNGBDBM50440069(CHEMBL2426071)
Affinity DataIC50:  4.00E+3nMAssay Description:Negative allosteric modulation of recombinant rat GluN2D receptor expressed in Xenopus laevis oocytes by two-electrode voltage clamp methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 107 total ) | Next | Last >>
Jump to: