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Found 666 Enz. Inhib. hit(s) with Target = 'Proteasome subunit beta type-1'
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599558(CHEMBL5182929)
Affinity DataKi:  21nMAssay Description:Inhibition of human spleen 20S immuno proteosome beta1i subunit assessed as substrate hydrolysis using Ac-Pro-Ala-Leu-AMC as fluorogenic substrate by...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  130nMAssay Description:Inhibition of 20s immunoproteasome beta1 caspase-like activity in human spleen using Ac-Pro-Ala-Leu-AMC as substrate after 10 mins by fluorescence as...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  130nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Leu-al as substrateMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50021350(CHEMBL3287940)
Affinity DataKi:  240nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599556(CHEMBL5182479)
Affinity DataKi:  270nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic substrate...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50021352(CHEMBL3287943)
Affinity DataKi:  310nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444909(CHEMBL3099618)
Affinity DataKi:  340nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  470nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434766(CHEMBL2385812)
Affinity DataKi:  520nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444908(CHEMBL3099624)
Affinity DataKi:  670nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50021348(CHEMBL3287937)
Affinity DataKi:  690nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50021349(CHEMBL3287939)
Affinity DataKi:  990nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50444888(CHEMBL3099621)
Affinity DataKi:  1.02E+3nMAssay Description:Competitive inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate Linewea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50021351(CHEMBL3287942)
Affinity DataKi:  1.25E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434768(CHEMBL2385810)
Affinity DataKi:  1.38E+3nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434765(CHEMBL2385813)
Affinity DataKi:  1.42E+3nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434763(CHEMBL2385817)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434763(CHEMBL2385817)
Affinity DataKi:  1.55E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50021353(CHEMBL3287944)
Affinity DataKi:  2.04E+3nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50453681(CHEMBL4204445)
Affinity DataKi:  2.64E+3nMAssay Description:Inhibition of 20s immunoproteasome beta1 caspase-like activity in human spleen using Ac-Pro-Ala-Leu-AMC as substrate after 10 mins by fluorescence as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599552(CHEMBL5195299)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434760(CHEMBL2385820)
Affinity DataKi:  3.90E+3nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434767(CHEMBL2385811)
Affinity DataKi:  4.42E+3nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50021356(CHEMBL3287947)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20s immuno proteasome beta1i subunit assessed as substrate hydrolysis using Ac-Pro-Ala-Leu-AMC as f...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434764(CHEMBL2385814)
Affinity DataKi:  5.14E+3nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  5.52E+3nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50453645(CHEMBL4212662)
Affinity DataKi:  6.53E+3nMAssay Description:Inhibition of 20s immunoproteasome beta1 caspase-like activity in human spleen using Ac-Pro-Ala-Leu-AMC as substrate after 10 mins by fluorescence as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50195934(CHEMBL3977256)
Affinity DataKi:  8.59E+3nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50453650(CHEMBL4213821)
Affinity DataKi:  9.64E+3nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate after 10 mins by flu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599551(CHEMBL5207762)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434762(CHEMBL2385818)
Affinity DataKi:  1.36E+4nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599553(CHEMBL5198329)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410909(CHEMBL207591 | PSI)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599551(CHEMBL5207762)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of 20S constitutive proteosome beta1c subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434761(CHEMBL2385819)
Affinity DataKi:  1.76E+4nMAssay Description:Inhibition of human 20S proteasome post-glutamyl peptide hydrolyzing activity using Z-Leu-Leu-Glu-AMC as substrate measured over 10 mins by fluoresce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50434761(CHEMBL2385819)
Affinity DataKi:  1.76E+4nMAssay Description:Inhibition of PGPH-like activity of 20S proteasome in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibition of 20s constitutive proteasome beta1 caspase-like activity in human erythrocytes using Z-Leu-Leu-Glu-AMC as substrate after 10 mins by flu...More data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50069985((S)-4-methyl-2-(3-phenyl-propionylamino)-pentanoic...)
Affinity DataKi:  2.21E+4nMAssay Description:Inhibition of 20S constitutive proteosome beta1c subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Leu-al as substrateMore data for this Ligand-Target Pair
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50007719(CHEMBL3233441)
Affinity DataKi:  2.23E+4nMAssay Description:Inhibition of caspase-like activity of human 20S proteasome beta 1 subunit assessed as Cbz-Leu-Leu-Glu-AMC substrate hydrolysis after 10 mins by fluo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599552(CHEMBL5195299)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of 20S constitutive proteosome beta1c subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50195936(CHEMBL3612420)
Affinity DataKi:  3.13E+4nMAssay Description:Competitive inhibition of post-glutamyl peptide hydrolyzing activity of human 20S proteasome using Cbz-Leu-Leu-Glu-AMC as substrate measured for 10 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50069984((R)-1-((S)-2-((S)-2-(benzyloxycarbonyl)-4-methylpe...)
Affinity DataKi:  4.80E+4nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50599554(CHEMBL5172870)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of 20S immuno proteosome beta1i subunit (unknown origin) assessed as substrate hydrolysis using Z-Leu-Leu-Glu-AMC as fluorogenic substrate...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410903(CHEMBL207598)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410898(CHEMBL205757)
Affinity DataKi: >3.00E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410902(CHEMBL205687)
Affinity DataKi: >4.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410901(CHEMBL206413)
Affinity DataKi: >4.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410900(CHEMBL207425)
Affinity DataKi: >9.00E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410896(CHEMBL383122)
Affinity DataKi: >9.00E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Messina

Curated by ChEMBL
LigandPNGBDBM50410899(CHEMBL383674)
Affinity DataKi: >9.00E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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