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Found 108 Enz. Inhib. hit(s) with Target = 'Sex hormone-binding globulin'
TargetSex hormone-binding globulin(Rattus norvegicus)
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50367916(METHYLTRIENOLONE | Metribolone | R-1881)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of rat androgen binding protein (rABP) (n=9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of hSHBG (human sex hormone binding globulin )More data for this Ligand-Target Pair
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataIC50:  14nMAssay Description:Displacement of [3H]DHT from human SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSex hormone-binding globulin(Rattus norvegicus)
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataIC50:  23nMAssay Description:Inhibition of rat androgen binding protein (rABP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM17292((1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{...)
Affinity DataIC50:  50nMAssay Description:Displacement of [3H]DHT from human SHBGMore data for this Ligand-Target Pair
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50200091(8-hydroxy-7a-methyl-4,5,5a,5b,6,7,7a,8,9,10,10a,10...)
Affinity DataIC50:  950nMAssay Description:Displacement of [3H]DHT from human SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50240916((-)-3,4-divanillyltetrahydrofuran | (3R,4R)-3,4-Bi...)
Affinity DataIC50:  2.60E+3nMAssay Description:Displacement of [3H]DHT from human serum SHBGMore data for this Ligand-Target Pair
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50200092(4-(4-(3-fluoro-4-hydroxyphenyl)hexan-3-yl)benzene-...)
Affinity DataIC50:  1.04E+4nMAssay Description:Displacement of [3H]DHT from human SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50200093(2-(4-hydroxyphenyl)-1-propyl-2,3-dihydro-1H-inden-...)
Affinity DataIC50:  1.11E+4nMAssay Description:Displacement of [3H]DHT from human SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50166034(1-(2,4-Dihydroxy-phenyl)-2-(4-hydroxy-phenyl)-etha...)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibitory concentration against [3H]-DHT binding to human sex hormone-binding globulin (SHBG)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50166033(4-((1S,2S,5S,6S,9R)-5-Hydroxymethyl-6,8,9-trimethy...)
Affinity DataIC50:  2.24E+4nMAssay Description:Inhibitory concentration against [3H]-DHT binding to human sex hormone-binding globulin (SHBG)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50200090(4-(4-hydroxy-3-(hydroxymethyl)-5-methylbenzyl)-2-(...)
Affinity DataIC50:  4.82E+4nMAssay Description:Displacement of [3H]DHT from human SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50240921((-)-matairesinol | (2R,3R)-2,3-Bis(4-hydroxy-3-met...)
Affinity DataIC50:  5.20E+4nMAssay Description:Displacement of [3H]DHT from human serum SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50166035(4-((1R,2R,5R,6R,9R)-5-Hydroxymethyl-6,8,9-trimethy...)
Affinity DataIC50:  1.25E+5nMAssay Description:Inhibitory concentration against [3H]-DHT binding to human sex hormone-binding globulin (SHBG)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50250505((-)-(2R,3R)-Secoisolariciresinol | (-)-secoisolari...)
Affinity DataIC50:  2.30E+5nMAssay Description:Displacement of [3H]DHT from human serum SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50250487((+/-)-enterolactone | CHEMBL465152)
Affinity DataIC50:  6.20E+5nMAssay Description:Displacement of [3H]DHT from human serum SHBGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423534(4-Methyl-Testosterone | CHEMBL265925)
Affinity DataKd:  0.490nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50368998(CHEMBL265926)
Affinity DataKd:  0.479nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423535(7Alpha-Methyldihydrotestosterone | CHEMBL411053)
Affinity DataKd:  0.417nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423536(17-Ethinyl-Dihydrotestosterone | CHEMBL260202)
Affinity DataKd:  0.182nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50410532(4-NONYLPHENOL)
Affinity DataKd:  1.20E+3nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50191348((3alpha,5beta)-3-hydroxyandrostan-17-one | 3alpha-...)
Affinity DataKd:  708nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50170653((11beta)-11,21-dihydroxypregn-4-ene-3,20-dione | 1...)
Affinity DataKd:  457nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423537(CHEMBL260658)
Affinity DataKd:  363nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50240921((-)-matairesinol | (2R,3R)-2,3-Bis(4-hydroxy-3-met...)
Affinity DataKd:  309nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423538(CHEMBL259313)
Affinity DataKd:  138nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)
Affinity DataKd:  71nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423539(11-Deoxycortisol | CORTODOXONE | Cortexolone | SK&...)
Affinity DataKd:  36nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423540(CHEMBL259635)
Affinity DataKd:  21nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50148732(17-ethynyl-17beta-hydroxyestr-4-en-3-one | 17alpha...)
Affinity DataKd:  11nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423541(DANAZOL | Danocrine | WIN-17757)
Affinity DataKd:  6.30nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423542(CHEMBL261407)
Affinity DataKd:  5.40nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423543(19-Nor-Dihydrotestosterone | CHEMBL260641)
Affinity DataKd:  4.40nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50410531(Android | Android 10 | Android 25 | Android 5 | ME...)
Affinity DataKd:  3.70nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423544(EQUILIN)
Affinity DataKd:  3.10nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423545(EQUILENIN)
Affinity DataKd:  2.40nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423546(BOLASTERONE | U-19763)
Affinity DataKd:  1.70nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423547(MESTANOLONE)
Affinity DataKd:  1.60nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423548(CHEMBL410519)
Affinity DataKd:  1.20nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423549(6Alpha-Fluoro-Dihydrotestosterone | CHEMBL408707)
Affinity DataKd:  0.891nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50093445((3alpha,5alpha,17beta)-androstane-3,17-diol | 3alp...)
Affinity DataKd:  0.776nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM8885((1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethylte...)
Affinity DataKd:  0.631nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423550(CHEMBL259126)
Affinity DataKd:  0.288nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423551(MESTEROLONE | SH-723)
Affinity DataKd:  0.251nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50300786(5-[125I]Iodo-3'-O-(17beta-succinyl-5alpha-androsta...)
Affinity DataKd:  17.2nMAssay Description:Binding affinity to human sex hormone binding globulin after 30 mins by size-exclusion HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM18161((1S,2S,7S,10R,11S,14S,15S)-14-hydroxy-2,15-dimethy...)
Affinity DataKd:  0.182nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423497(CHEMBL265939 | ZINC 00457465[36])
Affinity DataKd:  2.19E+3nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM23419((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...)
Affinity DataKd:  955nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423498(CHEMBL265940 | ZINC 00334865)
Affinity DataKd:  832nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50423499(CHEMBL259383 | ZINC 02819939)
Affinity DataKd:  589nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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