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Found 262 Enz. Inhib. hit(s) with Target = 'Tubulin beta-2B chain'
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataKi:  180nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109343(1-Methyl-5-[(S)-5-(3,4,5-trimethoxy-phenyl)-4,5-di...)
Affinity DataKi:  630nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataKi:  780nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50109342(1-Methyl-5-[(R)-5-(3,4,5-trimethoxy-phenyl)-4,5-di...)
Affinity DataKi:  3.69E+3nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50159524(CHEMBL20705 | N-(5-Chloro-1H-indol-7-yl)-4-methoxy...)
Affinity DataKi:  7.00E+3nMAssay Description:Binding affinity against tubulin from goat brain relative to colchicineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50159525(CHEMBL20827 | N-(4-Chloro-1H-indol-7-yl)-4-methoxy...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity against tubulin from goat brain relative to colchicineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50120462(CHEMBL20289 | N-(3-Chloro-1H-indol-7-yl)-4-methoxy...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity against tubulin from goat brain relative to colchicineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50159526(CHEMBL280959 | N-(1H-Indol-7-yl)-4-methoxy-benzene...)
Affinity DataKi:  1.40E+4nMAssay Description:Binding affinity against tubulin from goat brain relative to colchicineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50120465(CHEMBL281995 | N-(2-Chloro-1H-indol-7-yl)-4-methox...)
Affinity DataKi:  2.80E+4nMAssay Description:Binding affinity against tubulin from goat brain relative to colchicineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50012278((2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLAS...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding constant at colchicine site of bovine brain tubulinMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107672((3-Fluoro-phenyl)-(5-methoxy-1H-indol-2-yl)-methan...)
Affinity DataIC50:  390nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50035218(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Affinity DataIC50:  460nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50035218(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Affinity DataIC50:  460nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107658((5-Methoxy-1H-indol-2-yl)-phenyl-methanone | (5-me...)
Affinity DataIC50:  530nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107678((5-Methoxy-1H-indol-2-yl)-(3-methoxy-phenyl)-metha...)
Affinity DataIC50:  530nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  530nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  530nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037444(6-(3-Methoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50:  570nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50041130(6-Methoxy-2-phenyl-1H-quinolin-4-one | CHEMBL14120...)
Affinity DataIC50:  610nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50041123(6-(3,5-Dimethoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]qui...)
Affinity DataIC50:  620nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50059123(2-(3-Methoxy-phenyl)-5-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50:  620nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50005478(2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-ethyl]-ph...)
Affinity DataIC50:  630nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037464(6-Phenyl-5H-[1,3]dioxolo[4,5-g]quinolin-8-one | CH...)
Affinity DataIC50:  630nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107677((3-Hydroxy-phenyl)-(5-methoxy-1H-indol-2-yl)-metha...)
Affinity DataIC50:  660nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111568(2-Methoxy-5-[5-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)
Affinity DataIC50:  680nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50037452(6-(3-Dimethylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]q...)
Affinity DataIC50:  700nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50059100(6-Chloro-2-(3-methoxy-phenyl)-1H-[1,8]naphthyridin...)
Affinity DataIC50:  730nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111579(2-Methoxy-5-[5-(3,4,5-trimethoxy-phenyl)-3H-imidaz...)
Affinity DataIC50:  730nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50041100(6-Methoxy-2-(3-methoxy-phenyl)-1H-quinolin-4-one |...)
Affinity DataIC50:  740nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50059117(2-(3-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50:  750nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111574(1-Methyl-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-y...)
Affinity DataIC50:  790nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50059111(2-(3-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50:  800nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107676((3,4-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Affinity DataIC50:  810nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107656((3,5-Dimethoxy-phenyl)-(5-methoxy-1H-indol-2-yl)-m...)
Affinity DataIC50:  810nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50041121(2-(3-Dimethylamino-phenyl)-6-methoxy-1H-quinolin-4...)
Affinity DataIC50:  840nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107664((5-Methoxy-1H-indol-2-yl)-(3-nitro-phenyl)-methano...)
Affinity DataIC50:  850nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50041119(2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...)
Affinity DataIC50:  850nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107674(Butyric acid 3-(5-methoxy-1H-indole-2-carbonyl)-ph...)
Affinity DataIC50:  850nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107693((5-Methyl-1H-indol-2-yl)-(3,4,5-trimethoxy-phenyl)...)
Affinity DataIC50:  860nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111554(CHEMBL296066 | Dimethyl-{4-[4-(3,4,5-trimethoxy-ph...)
Affinity DataIC50:  870nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50059103(2-(3-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...)
Affinity DataIC50:  880nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50041106(6-(2-Chloro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50:  890nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50369013(CHEMBL1627442)
Affinity DataIC50:  910nMAssay Description:In vitro inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111558(2-Methoxy-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-...)
Affinity DataIC50:  920nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50059122(2-(3-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...)
Affinity DataIC50:  960nMAssay Description:Inhibition of bovine tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50111567(2-Methoxy-5-[4-(3,4,5-trimethoxy-phenyl)-oxazol-5-...)
Affinity DataIC50:  980nMAssay Description:Concentration needed to inhibit tubulin polymerization by 50%More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107662((3-Amino-phenyl)-(5-methoxy-1H-indol-2-yl)-methano...)
Affinity DataIC50:  990nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin beta-2B chain(Bos taurus)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50107651((5-Methoxy-1H-indol-2-yl)-(3,4,5-trimethoxy-phenyl...)
Affinity DataIC50:  990nMAssay Description:Inhibition of tubulin polymerization.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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