Compile Data Set for Download or QSAR
maximum 50k data
Found 227 Enz. Inhib. hit(s) with Target = 'cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma'
LigandPNGBDBM50188913(CHEMBL213618 | N-((S)-1-amino-3-(2,4-dichloropheny...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of PKAMore data for this Ligand-Target Pair
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of PKAMore data for this Ligand-Target Pair
LigandPNGBDBM50117504(CHEMBL3613620)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117489(CHEMBL3613598)
Affinity DataIC50: <1nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50044004(CHEMBL3356433)
Affinity DataIC50: <1nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117503(CHEMBL3613621)
Affinity DataIC50: <1nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117631(CHEMBL3613610)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117632(CHEMBL3613609)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117370(CHEMBL3613599)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117299(CHEMBL3613605)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117629(CHEMBL3613612)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
LigandPNGBDBM50117630(CHEMBL3613611)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117301(CHEMBL3613603)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117635(CHEMBL3613606)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117300(CHEMBL3613604)
Affinity DataIC50:  7nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  16nMAssay Description:Inhibition of Protein kinase AMore data for this Ligand-Target Pair
LigandPNGBDBM50117634(CHEMBL3613607)
Affinity DataIC50:  22nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117315(CHEMBL3613600)
Affinity DataIC50:  24nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117633(CHEMBL3613608)
Affinity DataIC50:  24nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM3153(2-{[2,6-dihydroxy-4-({[(1R,2R)-2-[(4-hydroxybenzen...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Protein kinase C gammaMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285250(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Protein Kinase AMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Protein kinase C epsilonMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50117627(CHEMBL3613614)
Affinity DataIC50:  69nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM3152(2-{[2,6-dihydroxy-4-({[(3R,4R)-4-[(4-hydroxybenzen...)
Affinity DataIC50:  70nMAssay Description:Inhibition of protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50285251(4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benz...)
Affinity DataIC50:  70nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  80nMAssay Description:Inhibition of cAMP-dependent protein kinase (Protein kinase A)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  80nMAssay Description:Inhibition of protein kinase A (PKA)More data for this Ligand-Target Pair
LigandPNGBDBM50117303(CHEMBL3613601)
Affinity DataIC50:  81nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117302(CHEMBL3613602)
Affinity DataIC50:  150nMAssay Description:Inhibition of PKA (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117502(CHEMBL3613622)
Affinity DataIC50:  332nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  790nMAssay Description:Inhibition of protein kinase C beta IIMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50192071((13R,15S)-13-methyl-16-oxa-8,9,12,22,24-pentaazahe...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of PKAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117500(CHEMBL3613624)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117626(CHEMBL3613615)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117625(CHEMBL3613616)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117501(CHEMBL3613623)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117505(CHEMBL3613619)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117581(CHEMBL3613618)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117598(CHEMBL3613617)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50117628(CHEMBL3613613)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of LIMK1 (unknown origin) by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM3154(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM2672(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM3158(2-{[2,6-dihydroxy-4-({[(4S)-3-[(4-hydroxybenzene)a...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Protein kinase C epsilonMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of protein kinase A.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM2581(3,13,23-triazahexacyclo[14.7.0.0^{2,10}.0^{4,9}.0^...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibitory activity against Cyclin D1-cyclin-dependent kinase 4 by measuring the phosphorylation of RbINGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50213033(CHEMBL329274)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of c-AMP dependent kinase (PKA) using histone II A proteinMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50366348(CHEMBL1233654)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of c-AMP dependent kinase (PKA) using histone II A proteinMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of PKAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of cAMP-dependent protein kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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