Found 4332 Enz. Inhib. hit(s) with Target = 'Ectonucleotide pyrophosphatase/phosphodiesterase family member 2'
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 6nMAssay Description:Competitive inhibition of human ATX expressed in HEK293 Flp-In cells assessed as decrease in LPC hydrolysis measured every 30 secs for 90 mins by Lin...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 6.10nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 8.10nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of rat ATX by Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 13nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 14nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Competitive inhibition of human ATX using LPC (16:0) as substrate after 30 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 15nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 17nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 18nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 19nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Rattus norvegicus)
University Of Strathclyde
Curated by ChEMBL
University Of Strathclyde
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of rat ATX by Michaelis-Menten analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 32nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 41nMAssay Description:Inhibition of ATX lysoPLD (unknown origin) using 18:1 LPC as substrate assessed as reduction in choline release by HVA fluorescence based analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 72nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 94nMAssay Description:Inhibition of autotoxin assessed as choline release from LPC using lysophosphatidylcholine as substrateMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Competitive inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 100nMAssay Description:Noncompetitive type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FR...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 187nMAssay Description:Inhibition of autotoxin assessed as choline release from LPC using lysophosphatidylcholine as substrateMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Competitive inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 200nMAssay Description:Noncompetitive type inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FR...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 270nMAssay Description:Mixed-type inhibition of human recombinant ATX using FS3 as substrate assessed as enzyme-inhibitor complex incubated for 2 hrs by Michaelis-Menten eq...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 271nMAssay Description:Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 280nMAssay Description:Mixed-type inhibition of human recombinant ATX using FS3 as substrate assessed as enzyme-substrate-inhibitor complex incubated for 2 hrs by Michaelis...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 367nMAssay Description:Inhibition of autotoxin assessed as choline release from LPC using lysophosphatidylcholine as substrateMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 390nMAssay Description:Inhibition of recombinant human C-terminal V5/His6-tagged ATX expressed in HEK293 cells assessed as choline release at 0.5 uM using oleoyl-lysophosph...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 500nMAssay Description:Competitive inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 512nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 700nMAssay Description:Competitive inhibition of human autotaxin at free state isolated from MDA-MB-231 cells assessed as blockade of FS3 substrate hydrolysis by FRET assayMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Competitive inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 800nMAssay Description:Inhibition of recombinant ATX mediated hydrolysis of FS-3More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 824nMAssay Description:Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 834nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.00E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.01E+3nMAssay Description:Inhibition of human recombinant ATX lysophospholipase activity expressed in insect sf9 cells using FS-3 fluorogenic substrate preincubated for 10 min...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.14E+3nMAssay Description:Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.30E+3nMAssay Description:Inhibition of recombinant human C-terminal V5/His6-tagged ATX expressed in HEK293 cells assessed as choline release at 0.5 uM using oleoyl-lysophosph...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.46E+3nMAssay Description:Competitive inhibition of human recombinant C-terminal FLAG-tagged autotaxin expressed in baculovirus-infected Sf9 cells assessed as FS-3 hydrolysis ...More data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.50E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Competitive inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Competitive inhibition of C-terminal FLAG-tagged human recombinant autotaxin using synthetic substrate FS-3 by Michaelis-Menten equation analysisMore data for this Ligand-Target Pair
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Homo sapiens (Human))
The Netherlands Institute
Curated by ChEMBL
The Netherlands Institute
Curated by ChEMBL
Affinity DataKi: 1.60E+3nMAssay Description:Inhibition of autotoxin assessed as choline production after 60 to 180 mins using lysophosphatidylcholine as a substrate by colorimetric methodMore data for this Ligand-Target Pair