BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 51058860 OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1 InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+ FXCKSJPZDBQRLO-KPKJPENVSA-N 50431947 CHEMBL2348091 Disintegrin and metalloproteinase domain-containing protein 17 >30000 ChEMBL 10.1016/j.bmcl.2013.01.121 10.7270/Q26974ZF 23453070 Atobe, M; Maekawara, N; Ishiguro, N; Sogame, S; Suenaga, Y; Kawanishi, M; Suzuki, H; Jinno, N; Tanaka, E; Miyoshi, S Asahi Kasei Pharma Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 71554128 164160822 CHEMBL2348091 ZINC95601814 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51058861 OC(=O)Cc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccc1 InChI=1S/C15H12N2O3S2/c18-11-8-21-12(16-11)7-13-17-15(9-4-2-1-3-5-9)10(22-13)6-14(19)20/h1-5,7H,6,8H2,(H,16,18)(H,19,20)/b12-7+ JFYUPKXGFNQNTK-KPKJPENVSA-N 50431942 CHEMBL2347847 Disintegrin and metalloproteinase domain-containing protein 17 16000 ChEMBL 10.1016/j.bmcl.2013.01.121 10.7270/Q26974ZF 23453070 Atobe, M; Maekawara, N; Ishiguro, N; Sogame, S; Suenaga, Y; Kawanishi, M; Suzuki, H; Jinno, N; Tanaka, E; Miyoshi, S Asahi Kasei Pharma Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 71579823 164160817 CHEMBL2347847 ZINC49772158 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42590 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1 CVZIHNYAZLXRRS-HNNXBMFYSA-N 23498 (3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL207729::TMI-1 Disintegrin and metalloproteinase domain-containing protein 17 8.4 7.4 22.00 C Curated from the literature by BindingDB 10.1124/jpet.103.059675 10.7270/Q2K935VD 14718605 aid1798325 Zhang, Y; Xu, J; Levin, J; Hegen, M; Li, G; Robertshaw, H; Brennan, F; Cummons, T; Clarke, D; Vansell, N; Nickerson-Nutter, C; Barone, D; Mohler, K; Black, R; Skotnicki, J; Gibbons, J; Feldmann, M; Frost, P; Larsen, G; Lin, LL Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23498&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search IH6 1ZXC 5288615 50091760 CHEMBL207729 DB07964 ZINC03817227 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42598 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H28N2O7S2/c1-4-5-14-29-17-6-8-18(9-7-17)30(25,26)15-20(19(23)21-24)10-12-22(13-11-20)31(27,28)16(2)3/h6-9,16,24H,10-15H2,1-3H3,(H,21,23) CEVLUPQNDFOYSI-UHFFFAOYSA-N 23500 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::CHEMBL209970::beta-sulfonyl hydroxamate analogue, 4 Disintegrin and metalloproteinase domain-containing protein 17 3 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23500&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11634234 50091761 CHEMBL209970 ZINC06718474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42599 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC(C)(C)C)C(=O)NO InChI=1S/C22H30N2O7S/c1-5-6-15-30-17-7-9-18(10-8-17)32(28,29)16-22(19(25)23-27)11-13-24(14-12-22)20(26)31-21(2,3)4/h7-10,27H,11-16H2,1-4H3,(H,23,25) XOBSNYRLSVUYKY-UHFFFAOYSA-N 23501 BMCL193445 Compound 2d::beta-sulfonyl hydroxamate analogue, 5::tert-butyl 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23501&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513850 50091762 ZINC28861970 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42600 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1 CVZIHNYAZLXRRS-HNNXBMFYSA-N 23498 (3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL207729::TMI-1 Disintegrin and metalloproteinase domain-containing protein 17 8 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23498&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search IH6 1ZXC 5288615 50091760 CHEMBL207729 DB07964 ZINC03817227 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42601 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC(C)(C)C)C(=O)NO InChI=1S/C22H31N3O6S/c1-5-6-13-23-17-7-9-18(10-8-17)32(29,30)16-22(19(26)24-28)11-14-25(15-12-22)20(27)31-21(2,3)4/h7-10,23,28H,11-16H2,1-4H3,(H,24,26) RXFCFGLSOUOCEA-UHFFFAOYSA-N 23502 beta-sulfonyl hydroxamate analogue, 7::tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 1.6 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23502 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23502&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 347 2PJT 24768528 50091763 DB07013 ZINC28861972 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42602 CC#CCN(C)c1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC(C)(C)C)C(=O)NO InChI=1S/C23H33N3O6S/c1-6-7-14-25(5)18-8-10-19(11-9-18)33(30,31)17-23(20(27)24-29)12-15-26(16-13-23)21(28)32-22(2,3)4/h8-11,29H,12-17H2,1-5H3,(H,24,27) VYJYRILYFYRPCK-UHFFFAOYSA-N 23503 beta-sulfonyl hydroxamate analogue, 11::tert-butyl 4-[({4-[but-2-yn-1-yl(methyl)amino]benzene}sulfonyl)methyl]-4-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 3.3 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23503 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23503&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860420 50091764 ZINC28861974 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42603 CC(C)(C)OC(=O)N1CCC(CS(=O)(=O)c2ccc(NCC#CCO)cc2)(CC1)C(=O)NO InChI=1S/C22H31N3O7S/c1-21(2,3)32-20(28)25-13-10-22(11-14-25,19(27)24-29)16-33(30,31)18-8-6-17(7-9-18)23-12-4-5-15-26/h6-9,23,26,29H,10-16H2,1-3H3,(H,24,27) HPBWNXRDTAWPAP-UHFFFAOYSA-N 23504 beta-sulfonyl hydroxamate analogue, 12::tert-butyl 4-[({4-[(4-hydroxybut-2-yn-1-yl)amino]benzene}sulfonyl)methyl]-4-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 10 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23504 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23504&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860421 50091765 ZINC28861976 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42604 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCNCC1)C(=O)NO InChI=1S/C17H23N3O4S/c1-2-3-10-19-14-4-6-15(7-5-14)25(23,24)13-17(16(21)20-22)8-11-18-12-9-17/h4-7,18-19,22H,8-13H2,1H3,(H,20,21) CEVWXUVNZJTNNB-UHFFFAOYSA-N 23505 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-N-hydroxypiperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 16 Disintegrin and metalloproteinase domain-containing protein 17 64.5 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23505 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23505&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860422 50091766 ZINC28861978 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42605 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H29N3O6S2/c1-4-5-12-21-17-6-8-18(9-7-17)30(26,27)15-20(19(24)22-25)10-13-23(14-11-20)31(28,29)16(2)3/h6-9,16,21,25H,10-15H2,1-3H3,(H,22,24) CIPRRERRNXDHQR-UHFFFAOYSA-N 23506 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 17 Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23506 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23506&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860423 50091767 ZINC28861979 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42606 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCN(Cc2ccncc2)CC1)C(=O)NO InChI=1S/C23H28N4O4S/c1-2-3-12-25-20-4-6-21(7-5-20)32(30,31)18-23(22(28)26-29)10-15-27(16-11-23)17-19-8-13-24-14-9-19/h4-9,13-14,25,29H,10-12,15-18H2,1H3,(H,26,28) CLSBMSGIRGYRMI-UHFFFAOYSA-N 23507 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-N-hydroxy-1-(pyridin-4-ylmethyl)piperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 18 Disintegrin and metalloproteinase domain-containing protein 17 6.4 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23507 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23507&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860424 50091768 ZINC28861981 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42607 CCN(CC)C(=O)N1CCC(CS(=O)(=O)c2ccc(NCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C22H32N4O5S/c1-4-7-14-23-18-8-10-19(11-9-18)32(30,31)17-22(20(27)24-29)12-15-26(16-13-22)21(28)25(5-2)6-3/h8-11,23,29H,5-6,12-17H2,1-3H3,(H,24,27) HGILVKJBXAXGDH-UHFFFAOYSA-N 23508 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-1-N,1-N-diethyl-4-N-hydroxypiperidine-1,4-dicarboxamide::beta-sulfonyl hydroxamate analogue, 19 Disintegrin and metalloproteinase domain-containing protein 17 <1 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23508 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23508&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860425 50091769 ZINC28861983 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42608 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccccc1C)C(=O)NO InChI=1S/C25H29N3O5S/c1-3-4-15-26-20-9-11-21(12-10-20)34(32,33)18-25(24(30)27-31)13-16-28(17-14-25)23(29)22-8-6-5-7-19(22)2/h5-12,26,31H,13-18H2,1-2H3,(H,27,30) IHSDOJRAORURAS-UHFFFAOYSA-N 23509 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-N-hydroxy-1-[(2-methylphenyl)carbonyl]piperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 20 Disintegrin and metalloproteinase domain-containing protein 17 2.5 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23509 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23509&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860426 50091770 ZINC28861984 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42609 CCC(C)C(=O)N1CCC(CS(=O)(=O)c2ccc(NCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C22H31N3O5S/c1-4-6-13-23-18-7-9-19(10-8-18)31(29,30)16-22(21(27)24-28)11-14-25(15-12-22)20(26)17(3)5-2/h7-10,17,23,28H,5,11-16H2,1-3H3,(H,24,27) CBEZXYHTYKUDTE-UHFFFAOYSA-N 23510 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-N-hydroxy-1-(2-methylbutanoyl)piperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 21 Disintegrin and metalloproteinase domain-containing protein 17 3.5 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23510 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23510&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860427 50091771 ZINC28861988 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42610 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)C(C)C)C(=O)NO InChI=1S/C21H29N3O5S/c1-4-5-12-22-17-6-8-18(9-7-17)30(28,29)15-21(20(26)23-27)10-13-24(14-11-21)19(25)16(2)3/h6-9,16,22,27H,10-15H2,1-3H3,(H,23,26) DYUKSKSACQYNBM-UHFFFAOYSA-N 23511 4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl)-N-hydroxy-1-(2-methylpropanoyl)piperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 22 Disintegrin and metalloproteinase domain-containing protein 17 2.3 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23511 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23511&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23625454 50091772 ZINC28861990 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42611 CC#CCNc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C17H23N3O4S2/c1-4-5-10-18-13-6-8-14(9-7-13)26(23,24)20-11-12-25-17(2,3)15(20)16(21)19-22/h6-9,15,18,22H,10-12H2,1-3H3,(H,19,21)/t15-/m0/s1 YLRFPZVTHHHQAF-HNNXBMFYSA-N 23512 (3S)-4-{[4-(but-2-yn-1-ylamino)benzene]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::beta-sulfonyl hydroxamate analogue, 26 Disintegrin and metalloproteinase domain-containing protein 17 2.3 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23512 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23512&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860428 50091773 ZINC28861997 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42612 CC#CC(C)Oc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C21H30N2O7S2/c1-5-6-17(4)30-18-7-9-19(10-8-18)31(26,27)15-21(20(24)22-25)11-13-23(14-12-21)32(28,29)16(2)3/h7-10,16-17,25H,11-15H2,1-4H3,(H,22,24) UFOCAFMHHPCHKN-UHFFFAOYSA-N 23513 N-hydroxy-4-({[4-(pent-3-yn-2-yloxy)benzene]sulfonyl}methyl)-1-(propane-2-sulfonyl)piperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 27 Disintegrin and metalloproteinase domain-containing protein 17 4 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23513 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23513&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860429 50091774 ZINC28861993 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 42613 CC#CC(C)(C)Oc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C22H32N2O7S2/c1-6-11-21(4,5)31-18-7-9-19(10-8-18)32(27,28)16-22(20(25)23-26)12-14-24(15-13-22)33(29,30)17(2)3/h7-10,17,26H,12-16H2,1-5H3,(H,23,25) SVFGAFGHEBEAJE-UHFFFAOYSA-N 23514 N-hydroxy-4-[({4-[(2-methylpent-3-yn-2-yl)oxy]benzene}sulfonyl)methyl]-1-(propane-2-sulfonyl)piperidine-4-carboxamide::beta-sulfonyl hydroxamate analogue, 28 Disintegrin and metalloproteinase domain-containing protein 17 27 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmc.2007.06.031 10.7270/Q2FJ2F3N 17606376 aid1798328 Huang, A; Joseph-McCarthy, D; Lovering, F; Sun, L; Wang, W; Xu, W; Zhu, Y; Cui, J; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23514 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23514&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24860430 50091775 ZINC28861995 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54801 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCNCC2)C(=O)NO)c2ccccc2n1 InChI=1S/C23H25N3O5S/c1-16-14-17(20-4-2-3-5-21(20)25-16)15-31-18-6-8-19(9-7-18)32(29,30)23(22(27)26-28)10-12-24-13-11-23/h2-9,14,24,28H,10-13,15H2,1H3,(H,26,27) OVRNSWPIJUFVHN-UHFFFAOYSA-N 30134 alpha-sulfone piperidine hydroxamate, 11a Disintegrin and metalloproteinase domain-containing protein 17 33 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30134&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143474 85147895 ZINC40429660 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54802 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCNCC1)C(=O)NO InChI=1S/C16H20N2O5S/c1-2-3-12-23-13-4-6-14(7-5-13)24(21,22)16(15(19)18-20)8-10-17-11-9-16/h4-7,17,20H,8-12H2,1H3,(H,18,19) PVOQKYVUWAHQSO-UHFFFAOYSA-N 30135 alpha-sulfone piperidine hydroxamate, 1a Disintegrin and metalloproteinase domain-containing protein 17 201 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30135&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10134897 85147896 ZINC34292469 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54803 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCNCC1)C(=O)NO InChI=1S/C17H22N2O5S/c1-2-3-12-24-14-4-6-15(7-5-14)25(22,23)13-17(16(20)19-21)8-10-18-11-9-17/h4-7,18,21H,8-13H2,1H3,(H,19,20) HTEPICDCVMJOSJ-UHFFFAOYSA-N 30136 CHEMBL385821::beta-sulfone piperidine hydroxamate, 2a Disintegrin and metalloproteinase domain-containing protein 17 1 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30136&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143475 85147897 CHEMBL385821 ZINC34802398 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54804 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCN(CC2)C=O)C(=O)NO)c2ccccc2n1 InChI=1S/C24H25N3O6S/c1-17-14-18(21-4-2-3-5-22(21)25-17)15-33-19-6-8-20(9-7-19)34(31,32)24(23(29)26-30)10-12-27(16-28)13-11-24/h2-9,14,16,30H,10-13,15H2,1H3,(H,26,29) DVAPUVGZYOTZOY-UHFFFAOYSA-N 30137 alpha-sulfone piperidine hydroxamate, 11b Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30137&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143476 85147898 ZINC40954315 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54805 CC(=O)N1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C25H27N3O6S/c1-17-15-19(22-5-3-4-6-23(22)26-17)16-34-20-7-9-21(10-8-20)35(32,33)25(24(30)27-31)11-13-28(14-12-25)18(2)29/h3-10,15,31H,11-14,16H2,1-2H3,(H,27,30) VOYWXVODQDUTJD-UHFFFAOYSA-N 30138 alpha-sulfone piperidine hydroxamate, 11c Disintegrin and metalloproteinase domain-containing protein 17 1 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30138&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11698938 85147899 ZINC38270392 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54806 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(CC1)C(C)=O)C(=O)NO InChI=1S/C18H22N2O6S/c1-3-4-13-26-15-5-7-16(8-6-15)27(24,25)18(17(22)19-23)9-11-20(12-10-18)14(2)21/h5-8,23H,9-13H2,1-2H3,(H,19,22) UZCHBPQXZPPPNZ-UHFFFAOYSA-N 30139 alpha-sulfone piperidine hydroxamate, 1b Disintegrin and metalloproteinase domain-containing protein 17 47 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30139&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15503645 85147900 ZINC40973358 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54807 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(C)=O)C(=O)NO InChI=1S/C19H24N2O6S/c1-3-4-13-27-16-5-7-17(8-6-16)28(25,26)14-19(18(23)20-24)9-11-21(12-10-19)15(2)22/h5-8,24H,9-14H2,1-2H3,(H,20,23) NPWNPFHGYNOBOO-UHFFFAOYSA-N 30140 CHEMBL380049::beta-sulfone piperidine hydroxamate, 2b Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30140&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9801569 85147901 CHEMBL380049 ZINC03924190 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54808 CC(C)C(=O)N1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C27H31N3O6S/c1-18(2)25(31)30-14-12-27(13-15-30,26(32)29-33)37(34,35)22-10-8-21(9-11-22)36-17-20-16-19(3)28-24-7-5-4-6-23(20)24/h4-11,16,18,33H,12-15,17H2,1-3H3,(H,29,32) LJJFKNOMQHHBEW-UHFFFAOYSA-N 30141 alpha-sulfone piperidine hydroxamate, 11d Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30141&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143477 85147902 ZINC40974938 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54809 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCN(CC2)C(=O)c2ccccc2)C(=O)NO)c2ccccc2n1 InChI=1S/C30H29N3O6S/c1-21-19-23(26-9-5-6-10-27(26)31-21)20-39-24-11-13-25(14-12-24)40(37,38)30(29(35)32-36)15-17-33(18-16-30)28(34)22-7-3-2-4-8-22/h2-14,19,36H,15-18,20H2,1H3,(H,32,35) VNIVLVJMMLQGNQ-UHFFFAOYSA-N 30142 alpha-sulfone piperidine hydroxamate, 11e Disintegrin and metalloproteinase domain-containing protein 17 1 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30142&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143478 85147903 ZINC42803279 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54810 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(CC1)C(=O)c1ccccc1)C(=O)NO InChI=1S/C23H24N2O6S/c1-2-3-17-31-19-9-11-20(12-10-19)32(29,30)23(22(27)24-28)13-15-25(16-14-23)21(26)18-7-5-4-6-8-18/h4-12,28H,13-17H2,1H3,(H,24,27) WUOWVIUWLFFAMY-UHFFFAOYSA-N 30143 alpha-sulfone piperidine hydroxamate, 1c Disintegrin and metalloproteinase domain-containing protein 17 73 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30143&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143479 85147904 ZINC40976250 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54811 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccccc1)C(=O)NO InChI=1S/C24H26N2O6S/c1-2-3-17-32-20-9-11-21(12-10-20)33(30,31)18-24(23(28)25-29)13-15-26(16-14-24)22(27)19-7-5-4-6-8-19/h4-12,29H,13-18H2,1H3,(H,25,28) HNEDFPGSHTUVKZ-UHFFFAOYSA-N 30144 CHEMBL212481::beta-sulfone piperidine hydroxamate, 2c Disintegrin and metalloproteinase domain-containing protein 17 1 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30144&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513825 85147905 CHEMBL212481 ZINC34801890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54812 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCN(CC2)C(=O)c2ccncc2)C(=O)NO)c2ccccc2n1 InChI=1S/C29H28N4O6S/c1-20-18-22(25-4-2-3-5-26(25)31-20)19-39-23-6-8-24(9-7-23)40(37,38)29(28(35)32-36)12-16-33(17-13-29)27(34)21-10-14-30-15-11-21/h2-11,14-15,18,36H,12-13,16-17,19H2,1H3,(H,32,35) RPWIXTPWMSUQKW-UHFFFAOYSA-N 30145 alpha-sulfone piperidine hydroxamate, 11f Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30145&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143480 85147906 ZINC42806447 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54813 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCN(CC2)C(=O)OC(C)(C)C)C(=O)NO)c2ccccc2n1 InChI=1S/C28H33N3O7S/c1-19-17-20(23-7-5-6-8-24(23)29-19)18-37-21-9-11-22(12-10-21)39(35,36)28(25(32)30-34)13-15-31(16-14-28)26(33)38-27(2,3)4/h5-12,17,34H,13-16,18H2,1-4H3,(H,30,32) IBMUIXAPDBZOLE-UHFFFAOYSA-N 30146 alpha-sulfone piperidine hydroxamate, 11g Disintegrin and metalloproteinase domain-containing protein 17 <1 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30146&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143481 85147907 ZINC49889138 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54814 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(CC1)C(=O)OC(C)(C)C)C(=O)NO InChI=1S/C21H28N2O7S/c1-5-6-15-29-16-7-9-17(10-8-16)31(27,28)21(18(24)22-26)11-13-23(14-12-21)19(25)30-20(2,3)4/h7-10,26H,11-15H2,1-4H3,(H,22,24) DIUYYSMPEUKBTJ-UHFFFAOYSA-N 30147 alpha-sulfone piperidine hydroxamate, 1d Disintegrin and metalloproteinase domain-containing protein 17 134 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30147&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11201814 85147908 ZINC38360290 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54815 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)OC(C)(C)C)C(=O)NO InChI=1S/C22H30N2O7S/c1-5-6-15-30-17-7-9-18(10-8-17)32(28,29)16-22(19(25)23-27)11-13-24(14-12-22)20(26)31-21(2,3)4/h7-10,27H,11-16H2,1-4H3,(H,23,25) XOBSNYRLSVUYKY-UHFFFAOYSA-N 23501 BMCL193445 Compound 2d::beta-sulfonyl hydroxamate analogue, 5::tert-butyl 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-4-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23501&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513850 50091762 ZINC28861970 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54816 CCNC(=O)N1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H30N4O6S/c1-3-27-25(32)30-14-12-26(13-15-30,24(31)29-33)37(34,35)21-10-8-20(9-11-21)36-17-19-16-18(2)28-23-7-5-4-6-22(19)23/h4-11,16,33H,3,12-15,17H2,1-2H3,(H,27,32)(H,29,31) XQTUJUSPSCMEOC-UHFFFAOYSA-N 30148 alpha-sulfone piperidine hydroxamate, 11h Disintegrin and metalloproteinase domain-containing protein 17 2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30148&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143482 85147909 ZINC40430861 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54817 CCN(CC)C(=O)N1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C28H34N4O6S/c1-4-31(5-2)27(34)32-16-14-28(15-17-32,26(33)30-35)39(36,37)23-12-10-22(11-13-23)38-19-21-18-20(3)29-25-9-7-6-8-24(21)25/h6-13,18,35H,4-5,14-17,19H2,1-3H3,(H,30,33) GKURRRNPHZGWQU-UHFFFAOYSA-N 30149 alpha-sulfone piperidine hydroxamate, 11i Disintegrin and metalloproteinase domain-containing protein 17 3 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30149&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143483 85147910 ZINC49889008 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54818 CN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C24H27N3O5S/c1-17-15-18(21-5-3-4-6-22(21)25-17)16-32-19-7-9-20(10-8-19)33(30,31)24(23(28)26-29)11-13-27(2)14-12-24/h3-10,15,29H,11-14,16H2,1-2H3,(H,26,28) BWCDPDUCUGVEMN-UHFFFAOYSA-N 30150 alpha-sulfone piperidine hydroxamate, 11j Disintegrin and metalloproteinase domain-containing protein 17 11 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30150&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143484 85147911 ZINC40956270 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54819 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCN(Cc3ccncc3)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C29H30N4O5S/c1-21-18-23(26-4-2-3-5-27(26)31-21)20-38-24-6-8-25(9-7-24)39(36,37)29(28(34)32-35)12-16-33(17-13-29)19-22-10-14-30-15-11-22/h2-11,14-15,18,35H,12-13,16-17,19-20H2,1H3,(H,32,34) WRDNQNGMPREKKZ-UHFFFAOYSA-N 30151 alpha-sulfone piperidine hydroxamate, 11k Disintegrin and metalloproteinase domain-containing protein 17 9 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30151&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143485 85147912 ZINC42891321 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54820 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCN(Cc3ccc(Cl)c(Cl)c3)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C30H29Cl2N3O5S/c1-20-16-22(25-4-2-3-5-28(25)33-20)19-40-23-7-9-24(10-8-23)41(38,39)30(29(36)34-37)12-14-35(15-13-30)18-21-6-11-26(31)27(32)17-21/h2-11,16-17,37H,12-15,18-19H2,1H3,(H,34,36) AAVVXYJNWGIBPT-UHFFFAOYSA-N 30152 alpha-sulfone piperidine hydroxamate, 11l Disintegrin and metalloproteinase domain-containing protein 17 65 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30152&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143486 85147913 ZINC44306356 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54821 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Cl)c(Cl)c2)CC1)C(=O)NO InChI=1S/C23H24Cl2N2O5S/c1-2-3-14-32-18-5-7-19(8-6-18)33(30,31)23(22(28)26-29)10-12-27(13-11-23)16-17-4-9-20(24)21(25)15-17/h4-9,15,29H,10-14,16H2,1H3,(H,26,28) MVCDTECIYPRJTL-UHFFFAOYSA-N 30153 alpha-sulfone piperidine hydroxamate, 1e Disintegrin and metalloproteinase domain-containing protein 17 149 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30153&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9914326 85147914 ZINC34026494 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54822 Cc1cc(COc2ccc(cc2)S(=O)(=O)C2(CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C24H27N3O7S2/c1-17-15-18(21-5-3-4-6-22(21)25-17)16-34-19-7-9-20(10-8-19)36(32,33)24(23(28)26-29)11-13-27(14-12-24)35(2,30)31/h3-10,15,29H,11-14,16H2,1-2H3,(H,26,28) CXZHJWRHSTZNHB-UHFFFAOYSA-N 30154 alpha-sulfone piperidine hydroxamate, 11m Disintegrin and metalloproteinase domain-containing protein 17 1.2 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30154&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143487 85147915 ZINC49881859 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 54823 CC(C)S(=O)(=O)N1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H31N3O7S2/c1-18(2)38(34,35)29-14-12-26(13-15-29,25(30)28-31)37(32,33)22-10-8-21(9-11-22)36-17-20-16-19(3)27-24-7-5-4-6-23(20)24/h4-11,16,18,31H,12-15,17H2,1-3H3,(H,28,30) JRSOKCXTAIQJPK-UHFFFAOYSA-N 30155 alpha-sulfone piperidine hydroxamate, 11n Disintegrin and metalloproteinase domain-containing protein 17 10 7.4 22.00 C Curated from the literature by BindingDB 10.1016/j.bmcl.2009.05.020 10.7270/Q2GT5KHW 19464885 aid1799066 Zhang, C; Lovering, F; Behnke, M; Zask, A; Sandanayaka, V; Sun, L; Zhu, Y; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30155&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143488 85147916 ZINC49881808 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 191747 C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 19190 (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one::CHEMBL131::Delta-Cortef::Deltacortril::Prednisolone::US10196374, Prednisolone Disintegrin and metalloproteinase domain-containing protein 17 14.9 US Patent 10.7270/Q2MC8XQM aid1800787 US8901310 Rucker, PV; Snyder, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=19190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=19190&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search TUA 8CC1,6W9K 5755 46519223 8378 CHEMBL131 DB00860 2866 C07369 ZINC03833821 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 191748 Cc1ncccc1CNC(=O)c1ccc2c(CC[C@@H]3C[C@@](O)(CCC(F)(F)F)CC[C@@]23Cc2ccccc2)c1 InChI=1S/C32H35F3N2O2/c1-22-26(8-5-17-36-22)21-37-29(38)25-10-12-28-24(18-25)9-11-27-20-30(39,14-16-32(33,34)35)13-15-31(27,28)19-23-6-3-2-4-7-23/h2-8,10,12,17-18,27,39H,9,11,13-16,19-21H2,1H3,(H,37,38)/t27-,30+,31+/m1/s1 KCAXPRFNWUOBNC-RDAHNBDFSA-N 140011 US8901310, Comparator A Disintegrin and metalloproteinase domain-containing protein 17 >1000 US Patent 10.7270/Q2MC8XQM aid1800787 US8901310 Rucker, PV; Snyder, JS Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=140011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=140011&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11444034 250184315 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 200489 OC(=O)c1cc(O)c(O)c(O)c1 InChI=1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12) LNTHITQWFMADLM-UHFFFAOYSA-N 50085536 3,4,5-Trihydroxybenzoate, X::3,4,5-trihydroxybenzoic acid::CHEMBL288114::Gallic Acid, F::gallic acid Disintegrin and metalloproteinase domain-containing protein 17 >200000 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.abb.2004.02.039 10.7270/Q20C4TCS 15081893 aid1799774 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50085536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50085536&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search GDE 4IC0,4J0H,3WRB,4Z5X,3WKU,3WPM,3WR9,3WR4,3WR3,7K4O 370 103984979 30778 CHEMBL288114 C01424 ZINC00001504 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 200490 Oc1cc(O)c2C[C@@H](OC(=O)c3cc(O)c(O)c(O)c3)[C@H](Oc2c1)c1cc(O)c(O)c(O)c1 InChI=1S/C22H18O11/c23-10-5-12(24)11-7-18(33-22(31)9-3-15(27)20(30)16(28)4-9)21(32-17(11)6-10)8-1-13(25)19(29)14(26)2-8/h1-6,18,21,23-30H,7H2/t18-,21-/m1/s1 WMBWREPUVVBILR-WIYYLYMNSA-N 50070942 (-)-Epigallocatechin gallate::(-)-Epigallocatechin-3-o-gallate::(-)-epigallocatechin 3-gallate::(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl 3,4,5-trihydroxybenzoate::CHEMBL297453::EGCG::Epigallocatechin 3-gallate::Epigallocatechin monogallate, B::cid_65064 Disintegrin and metalloproteinase domain-containing protein 17 21000 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.abb.2004.02.039 10.7270/Q20C4TCS 15081893 aid1799774 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search EGG 65064 103964753 4806 CHEMBL297453 7002 C09731 ZINC03870412 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 200491 Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O InChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1 QGWNDRXFNXRZMB-UUOKFMHZSA-N 92459 CHEMBL384759::GDP::Guanosine Diphosphate Disintegrin and metalloproteinase domain-containing protein 17 >200000 7.3 22.00 C Curated from the literature by BindingDB 10.1016/j.abb.2004.02.039 10.7270/Q20C4TCS 15081893 aid1799774 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=92459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=92459&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search GDP 7X56,1NG1,2NPF,6O62,6O61,4LC1,4M1K,4M1S,4M1W,4M1T,4M1Y,6WOO,7CYQ,5CA9,5CA8,5CA1,5CA0,5YXZ,5YXH,7SGS,6K9V,3NXS,5O74,7T3C,6GFU,7QI6,7QI4,2DXE,3W6P,6I5M,6I5C,7DB9,7DBC,7DBB,7DBA,6RVP,6RVQ,6RVN,6CY5,5HNW,5HNY,5HNX,5HNZ,4M8N,7ZX2,7ABZ,1KAO,6Y6D,3PEN,4ARZ,7MO4,6TAM,2HXF,6TH4,4LX0,7JII,4JVS,6T66,7N32,1T2A,5MLV,6SES,1SA1,1SA0,2QTH,3GJ8,7CPQ,2P2L,3WYA,3FFB,7S0Z,7ODN,7ODT,1MOZ,6QQN,2H5E,2PMD,4ESV,2HCJ,5E95,1S4O,6MTE,6MTD,4V8U,4V8Q,1RRG,1RRF,6VIJ,1R8S,3MOH,4ZHQ,5WDS,3SEA,7DON,4ZCL,1Q21,7BWT,7C1O,4Q46,6P8Z,6P8X,6P8Y,7SSD,5O7A,1GFI,3VDN,6KVQ,5IQG,1RE0,2C2H,7TNY,6GQB,4DSU,2WIB,5AFI,4R43,7YZ1,8AQ7,8AQ5,3TK1,6S9E,1KV3,2IC5,3L43,3OXJ,3OXB,6P5R,5AJ3,7KMR,6BT0,2FAH,3CON,7Y4A,5CK5,5CK4,5X6Z,1I4L,1I4D,5IJ9,5IJ0,2BOV,2BO7,7TAM,1SVK,1SVI,2FA9,3JAR,3JAS,1O87,7Q1F,7DP8,5NG1,5M54,5M50,5M5M,5M5L,5M5O,5M5N,5M5I,5M5C,5HPY,8A9T,8A9Z,1BHN,7VUJ,4L8G,1K5G,4M22,6PTA,2X77,1KSH,2BTQ,3REF,7TTE,7TTD,7TTF,8DKT,1SKQ,1ETU,6B0Y,1FNM,7MO5,6HZ8,6HZ9,6HZ4,6HZ5,6HZ6,6HZ7,1MEZ,7U2P,7R0Q,7R0N,7R0M,5EYP,1XJE,5XLZ,5XLT,1XJ0,7RRO,6TKZ,1XTQ,2W6D,5VP7,7A47,3CPJ,3CPH,2QU8,2QUZ,6USZ,6USX,4F61,5XDV,5XDT,4TQA,7Z0G,7Z0F,7PO3,3BBF,2Z1M,4MDE,5UF8,5KWK,7JFP,7JFR,5M8G,5M8D,4M21,6NAZ,7MO1,7MO2,3UMS,3UMR,7WZA,7WZC,6V6S,6V6V,6V6U,1U0L,7EVE,7EVL,7EVK,7MDP,2WWW,3C3E,7JMK,7BTC,7BTA,7Z02,5Z4U,5Z4P,5US4,5S5Q,5OT7,5S5Y,5S5F,6TAN,5S5I,4XC6,4XCQ,1RPN,5YLJ,5YL4,5YL2,4CK6,4CK7,4CK5,1CG1,4NON,3DEF,5IGY,4DRZ,3SJZ,2WJJ,2WJH,2WJG,5WHD,5WHA,5WHB,1ZUN,1JFF,5NM5,4O4L,5HZK,7U8H,5BWM,2OM2,3Q5E,3Q5D,6BSX,6BS2,1DG1,1GRN,4PC3,1IA0,3QOF,6KZB,7MNU,5CJ2,5CJV,5CJW,5CJT,5CJU,5OV7,7T47,1CRQ,6ZXQ,4NXX,4NXV,8DAK,5MLB,4IDQ,4IDO,5MLZ,3J4S,4GMW,2AL7,2RGN,7RP3,7RP2,7RP4,7RPZ,8ASN,1Z6Y,1Z6X,1AGR,6WWL,6N2K,4WTI,4WTE,3B1W,1FFX,2J68,6LOJ,2DCU,3ZY2,3ZY3,7LHT,7LHW,3LVR,3LVQ,6Y4N,6Y4M,1IJF,5YZ3,3AH8,1G16,3RB8,4C7O,1H65,7M6J,1U8Z,6D88,3IR6,7S0Y,4ATX,4ATU,2F7S,3OXE,6E6G,7LS1,1Z0D,1Z0F,1Z0I,4LV6,4LV5,4LV8,4OJK,3QY0,1RYA,1RYF,4ZDW,5VQ8,5VQ0,5VQ1,3T1O,3T1V,3T1T,3T12,5MN4,5MN6,7QTM,6UPR,6UPQ,6UPA,4F9F,4F97,4F96,1FZQ,5U32,4RCY,4RCG,3X1W,3X1D,2H7V,7PJZ,7PJY,7PJX,7PJW,7PJV,7PJI,5XXT,6MZE,6MZG,2L0X,6V5V,6V5L,5J2U,5J2T,8ETD,4EB6,3DKD,6VO6,3U6B,3U6K,7LS2,3LXR,6BOF,3TR5,4HI0,2HJG,1MRE,3O47,7PUB,7CLD,6KPP,2MSC,6WJ3,6WJ2,3RYI,3RYC,7THY,7THZ,7CBZ,2GAO,7L08,4Z87,4Z8Y,5ZJ5,7US5,4J0Q,6BR1,6BRY,6BRF,3E70,3QNU,6WGH,1TQ4,5CIW,3AB3,6MLR,6MLQ,7KZO,5X4B,6JCJ,2BMD,2BM1,2BM0,5VGR,4IEN,2QA5,2QAG,2GTP,7E5A,7E5E,3DIY,7UG7,2A78,7M18,5M7G,5M7E,3V00,1KY3,6EVX,6EVZ,7L3V,7L3M,6N12,3ZF8,2DBY,6E88,7LI3,7LI4,3LWN,3LW8,2X1V,5FNV,2P4N,4PAN,4P3Y,3N5C,5AJ4,4DCS,1TPZ,1JUY,6U05,6U0U,6U0T,6U0H,6ZL5,1CC0,8DIQ,4DKX,4DJT,4YJ3,4YJ2,1HA3,6I0M,1AS3,6CTZ,1D2E,1VG9,1VG0,1VG1,5N6O,3VQT,4W2E,4W29,4LUC,8BDE,1YZG,4V0K,3QXX,1FQJ,1FQK,6YR8,1U90,6LL6,6LL5,1EK0,6UQQ,5T02,4I1O,7BWV,7OI2,5NKK,4DCU,4DCT,5KUT,5KU1,7ALR,1DS6,6DZH,2I8U,6KNZ,7EQ2,2J1L,5IYZ,1U2R,3V70,6VNO,5W75,5W7Q,5C2J,5C2K,5V3A,6ULG,6P8W,5KOR,4G5O,4G5G,4G5Q,2ODE,4MYT,4MYU,1BYU,7YYP,7YYW,7YYV,6PC4,7SSL,6L6O,7UN1,7A1W,1S4P,5IRC,5D3Q,2XNS,4PDE,6H35,4R4V,4R4P,7KZM,2J0V,3CH5,2A9K,6XET,6XES,6XER,5XXW,2HT6,1KSJ,5TDH,2IF0,8BSI,6OIM,3ZP8,7LGI,3BB3,6NNG,1GP2,8C5C,4JYC,1YRA,5LXT,5LXS,5IGR,5IGW,6KVP,2QF2,6QUS,6MZF,3SYN,6R3V,5YMX,3I8X,1Z0A,5M6X,4EPT,4EPW,7N6G,4EPY,4EPX,6EW0,6N0B,3ONW,4UXO,4UXT,4UXP,4UXR,3LX8,6NZD,3LXX,6NZ6,6NZ4,6NZ5,5IQF,2YDC,6WS2,6WS4,5FOE,1CG0,1CG3,1CG4,4EKD,4EKC,5YT0,1G7S,3HKD,3HKE,3HKB,3HKC,5O33,8DHB,3J9M,7C41,7BAI,5JH7,1MF0,2Z95,6QVJ,6QVE,5EZY,5EZ6,5JQG,7BVU,5XC3,5XCO,6TDE,2CJW,3GP9,1U81,2QM7,6GZE,6W4F,6W4X,7C40,7NY8,5MI9,5MI8,5MIO,3T34,3T35,4GNK,2P5S,4GNL,5ZVP,1E0S,1HUR,1TAD,1TAG,7OHN,7OHL,7OHK,7OHH,1MKY,1ZCA,1ZCB,5UK9,2H18,2J3E,5MRC,5MRE,5MRF,4M1O,1DPF,5W22,3KKQ,7EPK,2FMX,6VMI,3DM5,5C1S,3MSX,6STF,6UMK,2FPG,7Q9U,3FQJ,6X1C,6X1E,6X1F,2IK8,5S63,5S61,5S66,5S67,2ZU9,5LA6,1DOA,7CNN,7CNO,5FR2,5FR1,5XIW,5S64,5S65,6ZPI,3RWO,6M9W,5JUS,5JUP,5JUT,5JUU,5JUO,7F0W,2GCQ,4RD0,2GCN,4RD1,3SOP,2ATV,2ATQ,7UG6,5H7K,5H74,6HH2,7Z2N,3OX0,8AFD,3OXM,2H17,2H16,3OXD,7AS4,5KTY,5OXF,6OJF,6OJE,7UQB,7UQZ,7UUI,7SZS,4LI0,3GEH,3GEE,1WMS,2B92,5OSK,5SYE,1CLQ,5XHC,2DYK,8DR4,8DR5,8DR3,8DR0,8DR1,5IGZ,5XAG,8BDF,8BDG,1HH4,2A5J,1GDD,1N6K,1N6I,7YZ5,7YZ2,7YZ0 8977 160844956 17552 CHEMBL384759 C00035 ZINC08215481 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236217 Oc1c(CC(=O)Nc2ccccc2)sc(=O)n1-c1ccccc1 InChI=1S/C17H14N2O3S/c20-15(18-12-7-3-1-4-8-12)11-14-16(21)19(17(22)23-14)13-9-5-2-6-10-13/h1-10,21H,11H2,(H,18,20) UDCUEJBCFVMLPG-UHFFFAOYSA-N 44587 2-(2,4-diketo-3-phenyl-thiazolidin-5-yl)-N-phenyl-acetamide::2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-phenylacetamide::2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-phenylacetamide::2-[2,4-bis(oxidanylidene)-3-phenyl-1,3-thiazolidin-5-yl]-N-phenyl-ethanamide::MLS000078498::SMR000036257::cid_660584 Disintegrin and metalloproteinase domain-containing protein 17 46664 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44587&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91896592 252625198 ZINC00269986 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236218 CC1CN(CC(C)O1)S(=O)(=O)c1ccc(NC(=O)c2cc(n[nH]2)-c2ccccc2O)cc1 InChI=1S/C22H24N4O5S/c1-14-12-26(13-15(2)31-14)32(29,30)17-9-7-16(8-10-17)23-22(28)20-11-19(24-25-20)18-5-3-4-6-21(18)27/h3-11,14-15,27H,12-13H2,1-2H3,(H,23,28)(H,24,25) NBKLJDOWJLNSOU-UHFFFAOYSA-N 113991 (5E)-N-[4-(2,6-dimethylmorpholin-4-yl)sulfonylphenyl]-5-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazole-3-carboxamide::(5E)-N-[4-(2,6-dimethylmorpholin-4-yl)sulfonylphenyl]-5-(6-oxocyclohexa-2,4-dien-1-ylidene)-1,2-dihydropyrazole-3-carboxamide::(5E)-N-[4-(2,6-dimethylmorpholino)sulfonylphenyl]-5-(6-ketocyclohexa-2,4-dien-1-ylidene)-3-pyrazoline-3-carboxamide::(5E)-N-[4-[(2,6-dimethyl-4-morpholinyl)sulfonyl]phenyl]-5-(6-oxo-1-cyclohexa-2,4-dienylidene)-1,2-dihydropyrazole-3-carboxamide::MLS000084096::SMR000047641::cid_5390013 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113991&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5390013 252663513 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236219 ONC(=O)c1ccc(OC(F)F)cc1 InChI=1S/C8H7F2NO3/c9-8(10)14-6-3-1-5(2-4-6)7(12)11-13/h1-4,8,13H,(H,11,12) FWRXDRYCPUODPN-UHFFFAOYSA-N 113830 4-(difluoromethoxy)-N-hydroxybenzamide::4-(difluoromethoxy)benzenecarbohydroxamic acid::4-[bis(fluoranyl)methoxy]-N-oxidanyl-benzamide::MLS000090171::SMR000024783::cid_3239185 Disintegrin and metalloproteinase domain-containing protein 17 29538 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113830&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3239185 252663363 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236220 Cc1cccc(N2CCN(CC2)C(=O)c2ccc(CS(=O)(=O)c3ccccc3C)o2)c1C InChI=1S/C25H28N2O4S/c1-18-8-6-9-22(20(18)3)26-13-15-27(16-14-26)25(28)23-12-11-21(31-23)17-32(29,30)24-10-5-4-7-19(24)2/h4-12H,13-17H2,1-3H3 YGQUBOCWYGOXIE-UHFFFAOYSA-N 38971 1-(2,3-dimethylphenyl)-4-(5-{[(2-methylphenyl)sulfonyl]methyl}-2-furoyl)piperazine::MLS000046825::SMR000032836::[4-(2,3-dimethylphenyl)-1-piperazinyl]-[5-[(2-methylphenyl)sulfonylmethyl]-2-furanyl]methanone::[4-(2,3-dimethylphenyl)piperazin-1-yl]-[5-[(2-methylphenyl)sulfonylmethyl]furan-2-yl]methanone::[4-(2,3-dimethylphenyl)piperazino]-[5-(o-tolylsulfonylmethyl)-2-furyl]methanone::cid_3241476 Disintegrin and metalloproteinase domain-containing protein 17 69590 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=38971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=38971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3241476 252619871 ZINC03058590 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236221 Cc1nc2ccc(cc2s1)S(=O)(=O)NCC(=O)NCc1ccc2OCOc2c1 InChI=1S/C18H17N3O5S2/c1-11-21-14-4-3-13(7-17(14)27-11)28(23,24)20-9-18(22)19-8-12-2-5-15-16(6-12)26-10-25-15/h2-7,20H,8-10H2,1H3,(H,19,22) XUQLYYHDKHWTTA-UHFFFAOYSA-N 113992 2-[(2-methyl-1,3-benzothiazol-6-yl)sulfonylamino]-N-piperonyl-acetamide::MLS000094109::N-(1,3-benzodioxol-5-ylmethyl)-2-[(2-methyl-1,3-benzothiazol-6-yl)sulfonylamino]acetamide::N-(1,3-benzodioxol-5-ylmethyl)-2-[(2-methyl-1,3-benzothiazol-6-yl)sulfonylamino]ethanamide::N~1~-(1,3-benzodioxol-5-ylmethyl)-N~2~-[(2-methyl-1,3-benzothiazol-6-yl)sulfonyl]glycinamide::SMR000029724::cid_3245421 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113992&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3245421 252663514 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236222 COC(=O)c1c(C)n(-c2ccc(OC)cc2)c2ccc(O)cc12 InChI=1S/C18H17NO4/c1-11-17(18(21)23-3)15-10-13(20)6-9-16(15)19(11)12-4-7-14(22-2)8-5-12/h4-10,20H,1-3H3 DPVJEMJNTMTDTP-UHFFFAOYSA-N 37106 5-hydroxy-1-(4-methoxyphenyl)-2-methyl-3-indolecarboxylic acid methyl ester::5-hydroxy-1-(4-methoxyphenyl)-2-methyl-indole-3-carboxylic acid methyl ester::MLS000051536::SMR000079967::cid_1508818::methyl 1-(4-methoxyphenyl)-2-methyl-5-oxidanyl-indole-3-carboxylate::methyl 5-hydroxy-1-(4-methoxyphenyl)-2-methyl-1H-indole-3-carboxylate::methyl 5-hydroxy-1-(4-methoxyphenyl)-2-methylindole-3-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37106&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1508818 252618077 ZINC01428761 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236223 O=C(N1CCC2(CC1)OCCO2)c1cc2CCCCCCc2s1 InChI=1S/C18H25NO3S/c20-17(19-9-7-18(8-10-19)21-11-12-22-18)16-13-14-5-3-1-2-4-6-15(14)23-16/h13H,1-12H2 SUIZUNVIMJKENG-UHFFFAOYSA-N 113993 1,4-dioxa-8-azaspiro[4.5]decan-8-yl(4,5,6,7,8,9-hexahydrocycloocta[b]thiophen-2-yl)methanone::8-(4,5,6,7,8,9-hexahydrocycloocta[b]thien-2-ylcarbonyl)-1,4-dioxa-8-azaspiro[4.5]decane::MLS000099815::SMR000080799::cid_2971521 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113993&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2971521 252663515 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236224 CCOc1cc2c3N(C(=O)C22C(C#N)=C(N)Oc4cc(O)ccc24)C(C)(C)C=C(C)c3c1 InChI=1S/C25H23N3O4/c1-5-31-15-9-16-13(2)11-24(3,4)28-21(16)18(10-15)25(23(28)30)17-7-6-14(29)8-20(17)32-22(27)19(25)12-26/h6-11,29H,5,27H2,1-4H3 LZLCJZTWCLYECW-UHFFFAOYSA-N 113994 2-amino-8'-ethoxy-7-hydroxy-4',4',6'-trimethyl-2'-oxo-4'H-spiro[chromene-4,1'-pyrrolo[3,2,1-ij]quinoline]-3-carbonitrile::MLS000049881::SMR000076933::cid_2956740 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113994&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2956740 242053892 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236225 OC(=O)CCC(=O)c1c[nH]c2ccccc12 InChI=1S/C12H11NO3/c14-11(5-6-12(15)16)9-7-13-10-4-2-1-3-8(9)10/h1-4,7,13H,5-6H2,(H,15,16) NLUOPJQCFYTMGC-UHFFFAOYSA-N 113995 4-(1H-indol-3-yl)-4-keto-butyric acid::4-(1H-indol-3-yl)-4-oxidanylidene-butanoic acid::4-(1H-indol-3-yl)-4-oxobutanoic acid::MLS000060927::SMR000069155::cid_730037 Disintegrin and metalloproteinase domain-containing protein 17 24919 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113995&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 730037 252663516 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236226 Cc1ccccc1-c1noc(n1)-c1ccc(O)cc1 InChI=1S/C15H12N2O2/c1-10-4-2-3-5-13(10)14-16-15(19-17-14)11-6-8-12(18)9-7-11/h2-9,18H,1H3 ZMXAKACKYKVMGO-UHFFFAOYSA-N 37275 4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene]-1-cyclohexa-2,5-dienone::4-[3-(2-methylphenyl)-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,5-dien-1-one::4-[3-(o-tolyl)-2H-1,2,4-oxadiazol-5-ylidene]cyclohexa-2,5-dien-1-one::MLS000112501::SMR000108415::cid_5407960 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37275 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37275&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5407960 252618246 ZINC13126576 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236227 CC1(O)N(Cc2ccccc2)C(=O)OC11CCCCC1 InChI=1S/C16H21NO3/c1-15(19)16(10-6-3-7-11-16)20-14(18)17(15)12-13-8-4-2-5-9-13/h2,4-5,8-9,19H,3,6-7,10-12H2,1H3 IUGBOSBIXHIIKB-UHFFFAOYSA-N 113996 3-benzyl-4-hydroxy-4-methyl-1-oxa-3-azaspiro[4.5]decan-2-one::4-hydroxy-4-methyl-3-(phenylmethyl)-1-oxa-3-azaspiro[4.5]decan-2-one::4-methyl-4-oxidanyl-3-(phenylmethyl)-1-oxa-3-azaspiro[4.5]decan-2-one::MLS000107807::SMR000103771::cid_3872332 Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113996&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3872332 252663517 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236228 Cc1cccc(c1)C1(OC(=O)c2ccccc12)c1cccc(C)c1 InChI=1S/C22H18O2/c1-15-7-5-9-17(13-15)22(18-10-6-8-16(2)14-18)20-12-4-3-11-19(20)21(23)24-22/h3-14H,1-2H3 KROILPPVVWCRKD-UHFFFAOYSA-N 113997 3,3-Di-m-tolyl-3H-isobenzofuran-1-one::3,3-bis(3-methylphenyl)-1-isobenzofuranone::3,3-bis(3-methylphenyl)-2-benzofuran-1-one::3,3-bis(m-tolyl)phthalide::MLS000122244::SMR000119648::cid_3090246 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113997&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3090246 252663518 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236229 CC(C)Nc1nc(NC(C)C)nc(n1)N(CCOc1ccc(Cl)cc1Cl)C#N InChI=1S/C18H23Cl2N7O/c1-11(2)22-16-24-17(23-12(3)4)26-18(25-16)27(10-21)7-8-28-15-6-5-13(19)9-14(15)20/h5-6,9,11-12H,7-8H2,1-4H3,(H2,22,23,24,25,26) OAKVQEUFBQIFTE-UHFFFAOYSA-N 113998 (4,6-Bis-isopropylamino-[1,3,5]triazin-2-yl)-[2-(2,4-dichloro-phenoxy)-ethyl]-cyanamide::2-[2,4-bis(chloranyl)phenoxy]ethyl-[4,6-bis(propan-2-ylamino)-1,3,5-triazin-2-yl]cyanamide::MLS000525694::SMR000116168::[4,6-bis(isopropylamino)-s-triazin-2-yl]-[2-(2,4-dichlorophenoxy)ethyl]cyanamide::[4,6-bis(propan-2-ylamino)-1,3,5-triazin-2-yl]-[2-(2,4-dichlorophenoxy)ethyl]cyanamide::cid_1116953 Disintegrin and metalloproteinase domain-containing protein 17 69508 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113998&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1116953 252663519 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236230 Clc1cccc(NCc2nnc(SCc3ccc(Cl)cc3Cl)o2)c1 InChI=1S/C16H12Cl3N3OS/c17-11-2-1-3-13(6-11)20-8-15-21-22-16(23-15)24-9-10-4-5-12(18)7-14(10)19/h1-7,20H,8-9H2 XQWNZDOKEOWJGW-UHFFFAOYSA-N 113999 (3-Chloro-phenyl)-[5-(2,4-dichloro-benzylsulfanyl)-[1,3,4]oxadiazol-2-ylmethyl]-amine::(3-chlorophenyl)-[[5-[(2,4-dichlorobenzyl)thio]-1,3,4-oxadiazol-2-yl]methyl]amine::3-chloranyl-N-[[5-[(2,4-dichlorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]methyl]aniline::3-chloro-N-[[5-[(2,4-dichlorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]methyl]aniline::3-chloro-N-[[5-[(2,4-dichlorophenyl)methylthio]-1,3,4-oxadiazol-2-yl]methyl]aniline::MLS000527009::SMR000117483::cid_3134132 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113999&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3134132 252663520 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236231 COc1cccc(c1)C1C(C#N)C(=N)Oc2c1oc(CO)cc2=O InChI=1S/C17H14N2O5/c1-22-10-4-2-3-9(5-10)14-12(7-18)17(19)24-15-13(21)6-11(8-20)23-16(14)15/h2-6,12,14,19-20H,8H2,1H3 JCALGHHTXMASMD-UHFFFAOYSA-N 114000 2-Amino-6-hydroxymethyl-4-(3-methoxy-phenyl)-8-oxo-4,8-dihydro-pyrano[3,2-b]pyran-3-carbonitrile::2-amino-6-(hydroxymethyl)-4-(3-methoxyphenyl)-8-oxo-4H-pyrano[3,2-b]pyran-3-carbonitrile::2-amino-8-keto-4-(3-methoxyphenyl)-6-methylol-4H-pyrano[3,2-b]pyran-3-carbonitrile::2-azanyl-6-(hydroxymethyl)-4-(3-methoxyphenyl)-8-oxidanylidene-4H-pyrano[3,2-b]pyran-3-carbonitrile::MLS000527716::SMR000120290::cid_3156521 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114000&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899704 252663521 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236232 O=C(CC(c1ccccc1)c1ccccc1)Nc1ccc2OCCOc2c1 InChI=1S/C23H21NO3/c25-23(24-19-11-12-21-22(15-19)27-14-13-26-21)16-20(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-12,15,20H,13-14,16H2,(H,24,25) IPHXJVYRKKJIQP-UHFFFAOYSA-N 77167 MLS000529299::N-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-3,3-diphenyl-propionamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3,3-diphenyl-propanamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3,3-diphenyl-propionamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3,3-diphenylpropanamide::SMR000121774::cid_2932804 Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77167&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2932804 252654270 ZINC02743260 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236233 CCOC(=O)c1cc(OC(=O)c2ccccc2OC)n(n1)-c1ccccc1 InChI=1S/C20H18N2O5/c1-3-26-20(24)16-13-18(22(21-16)14-9-5-4-6-10-14)27-19(23)15-11-7-8-12-17(15)25-2/h4-13H,3H2,1-2H3 DPYRAVRFXZCNIB-UHFFFAOYSA-N 44461 5-[(2-methoxyphenyl)-oxomethoxy]-1-phenyl-3-pyrazolecarboxylic acid ethyl ester::5-o-anisoyloxy-1-phenyl-pyrazole-3-carboxylic acid ethyl ester::MLS000538601::SMR000144638::cid_1256813::ethyl 5-(2-methoxybenzoyl)oxy-1-phenylpyrazole-3-carboxylate::ethyl 5-(2-methoxyphenyl)carbonyloxy-1-phenyl-pyrazole-3-carboxylate::ethyl 5-[(2-methoxybenzoyl)oxy]-1-phenyl-1H-pyrazole-3-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69548 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44461&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1256813 252625076 ZINC36389226 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236234 CCOc1ccc(c(C)c1C)S(=O)(=O)Nc1ccc(F)cc1 InChI=1S/C16H18FNO3S/c1-4-21-15-9-10-16(12(3)11(15)2)22(19,20)18-14-7-5-13(17)6-8-14/h5-10,18H,4H2,1-3H3 GJUCAVHSIPEIGQ-UHFFFAOYSA-N 114001 4-ethoxy-N-(4-fluorophenyl)-2,3-dimethyl-benzenesulfonamide::4-ethoxy-N-(4-fluorophenyl)-2,3-dimethylbenzenesulfonamide::MLS000531444::SMR000136422::cid_935391 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114001&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 935391 252663522 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236235 O=C(Nc1cccc(c1)-c1csc(n1)-c1ccccc1)c1cccs1 InChI=1S/C20H14N2OS2/c23-19(18-10-5-11-24-18)21-16-9-4-8-15(12-16)17-13-25-20(22-17)14-6-2-1-3-7-14/h1-13H,(H,21,23) IYYXLBPJIUPROM-UHFFFAOYSA-N 114002 MLS000519054::N-[3-(2-phenyl-1,3-thiazol-4-yl)phenyl]thiophene-2-carboxamide::N-[3-(2-phenyl-4-thiazolyl)phenyl]-2-thiophenecarboxamide::N-[3-(2-phenylthiazol-4-yl)phenyl]thiophene-2-carboxamide::SMR000129474::cid_3574419 Disintegrin and metalloproteinase domain-containing protein 17 69510 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114002&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3574419 252663523 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236236 COc1ccccc1NC(=O)Cn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O InChI=1S/C23H18ClN3O3/c1-30-20-9-5-4-8-19(20)25-21(28)14-27-23(29)18-7-3-2-6-17(18)22(26-27)15-10-12-16(24)13-11-15/h2-13H,14H2,1H3,(H,25,28) KWKLEJNEQIUZII-UHFFFAOYSA-N 114003 2-[4-(4-chlorophenyl)-1-keto-phthalazin-2-yl]-N-(2-methoxyphenyl)acetamide::2-[4-(4-chlorophenyl)-1-oxidanylidene-phthalazin-2-yl]-N-(2-methoxyphenyl)ethanamide::2-[4-(4-chlorophenyl)-1-oxo-2(1H)-phthalazinyl]-N-(2-methoxyphenyl)acetamide::2-[4-(4-chlorophenyl)-1-oxo-2-phthalazinyl]-N-(2-methoxyphenyl)acetamide::2-[4-(4-chlorophenyl)-1-oxophthalazin-2-yl]-N-(2-methoxyphenyl)acetamide::MLS000535273::SMR000142710::cid_1309611 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114003&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1309611 252663524 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236237 Cc1ccccc1-c1nc(c(NCc2cccnc2)o1)S(=O)(=O)c1ccc(Br)cc1 InChI=1S/C22H18BrN3O3S/c1-15-5-2-3-7-19(15)20-26-22(30(27,28)18-10-8-17(23)9-11-18)21(29-20)25-14-16-6-4-12-24-13-16/h2-13,25H,14H2,1H3 UBABCLZAIVIBOB-UHFFFAOYSA-N 114004 4-(4-bromophenyl)sulfonyl-2-(2-methylphenyl)-N-(3-pyridinylmethyl)-5-oxazolamine::4-(4-bromophenyl)sulfonyl-2-(2-methylphenyl)-N-(pyridin-3-ylmethyl)-1,3-oxazol-5-amine::4-[(4-bromophenyl)sulfonyl]-2-(2-methylphenyl)-N-(3-pyridinylmethyl)-1,3-oxazol-5-amine::MLS000538246::SMR000144288::[4-brosyl-2-(o-tolyl)oxazol-5-yl]-(3-pyridylmethyl)amine::cid_1244642 Disintegrin and metalloproteinase domain-containing protein 17 69508 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114004&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1244642 252663525 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236238 CCN1C(=S)N\C(=C/c2ccc(C)s2)C1=O InChI=1S/C11H12N2OS2/c1-3-13-10(14)9(12-11(13)15)6-8-5-4-7(2)16-8/h4-6H,3H2,1-2H3,(H,12,15)/b9-6- XTKQPAZINZWJOW-TWGQIWQCSA-N 114005 (5Z)-3-ethyl-5-[(5-methyl-2-thienyl)methylene]-2-thioxo-4-imidazolidinone::(5Z)-3-ethyl-5-[(5-methyl-2-thiophenyl)methylidene]-2-sulfanylidene-4-imidazolidinone::(5Z)-3-ethyl-5-[(5-methylthiophen-2-yl)methylidene]-2-sulfanylidene-imidazolidin-4-one::(5Z)-3-ethyl-5-[(5-methylthiophen-2-yl)methylidene]-2-sulfanylideneimidazolidin-4-one::MLS000534742::SMR000142199::cid_5400728 Disintegrin and metalloproteinase domain-containing protein 17 69548 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114005&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5400728 252663526 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236239 Cc1cc(Oc2ccccc2)nc(SCC(=O)Nc2ccc(Cl)c(Cl)c2)n1 InChI=1S/C19H15Cl2N3O2S/c1-12-9-18(26-14-5-3-2-4-6-14)24-19(22-12)27-11-17(25)23-13-7-8-15(20)16(21)10-13/h2-10H,11H2,1H3,(H,23,25) VQWSUALZZALCIX-UHFFFAOYSA-N 77289 MLS000536836::N-(3,4-dichlorophenyl)-2-(4-methyl-6-phenoxy-pyrimidin-2-yl)sulfanyl-ethanamide::N-(3,4-dichlorophenyl)-2-(4-methyl-6-phenoxypyrimidin-2-yl)sulfanylacetamide::N-(3,4-dichlorophenyl)-2-[(4-methyl-6-phenoxy-2-pyrimidinyl)thio]acetamide::N-(3,4-dichlorophenyl)-2-[(4-methyl-6-phenoxy-pyrimidin-2-yl)thio]acetamide::SMR000143473::cid_2202953 Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77289&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2202953 252654370 ZINC02849023 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236240 CNC(=O)C1CC(=O)N=C(NN=C(C)c2cccs2)S1 InChI=1S/C12H14N4O2S2/c1-7(8-4-3-5-19-8)15-16-12-14-10(17)6-9(20-12)11(18)13-2/h3-5,9H,6H2,1-2H3,(H,13,18)(H,14,16,17) CJDMJDXOYZCSEE-UHFFFAOYSA-N 114006 4-Oxo-2-{[1-thiophen-2-yl-eth-(E)-ylidene]-hydrazono}-[1,3]thiazinane-6-carboxylic acid methylamide::4-keto-N-methyl-2-[(N'E)-N'-[1-(2-thienyl)ethylidene]hydrazino]-5,6-dihydro-1,3-thiazine-6-carboxamide::MLS000556464::N-methyl-4-oxidanylidene-2-[(2E)-2-(1-thiophen-2-ylethylidene)hydrazinyl]-5,6-dihydro-1,3-thiazine-6-carboxamide::N-methyl-4-oxo-2-[(2E)-2-(1-thiophen-2-ylethylidene)hydrazinyl]-5,6-dihydro-1,3-thiazine-6-carboxamide::SMR000147781::cid_5766445 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114006&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5766445 252663527 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236241 O=C1CC(Nc2ccc3ccccc3c2)C(=O)N1Cc1ccccc1 InChI=1S/C21H18N2O2/c24-20-13-19(21(25)23(20)14-15-6-2-1-3-7-15)22-18-11-10-16-8-4-5-9-17(16)12-18/h1-12,19,22H,13-14H2 NYMDPNWQNYFALJ-UHFFFAOYSA-N 114007 1-Benzyl-3-(naphthalen-2-ylamino)-pyrrolidine-2,5-dione::1-benzyl-3-(2-naphthylamino)pyrrolidine-2,5-quinone::1-benzyl-3-(naphthalen-2-ylamino)pyrrolidine-2,5-dione::3-(2-naphthalenylamino)-1-(phenylmethyl)pyrrolidine-2,5-dione::3-(naphthalen-2-ylamino)-1-(phenylmethyl)pyrrolidine-2,5-dione::MLS000556860::SMR000147977::cid_3794468 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114007&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3794468 252663528 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236242 Cc1csc(n1)-c1cnn(c1NC(=O)c1ccc(cc1)C(F)(F)F)-c1ccccc1 InChI=1S/C21H15F3N4OS/c1-13-12-30-20(26-13)17-11-25-28(16-5-3-2-4-6-16)18(17)27-19(29)14-7-9-15(10-8-14)21(22,23)24/h2-12H,1H3,(H,27,29) PQJIGSQKFMOUCG-UHFFFAOYSA-N 114008 MLS000565975::N-[4-(4-methyl-1,3-thiazol-2-yl)-2-phenyl-pyrazol-3-yl]-4-(trifluoromethyl)benzamide::N-[4-(4-methyl-1,3-thiazol-2-yl)-2-phenylpyrazol-3-yl]-4-(trifluoromethyl)benzamide::N-[4-(4-methyl-2-thiazolyl)-2-phenyl-3-pyrazolyl]-4-(trifluoromethyl)benzamide::N-[4-(4-methylthiazol-2-yl)-2-phenyl-pyrazol-3-yl]-4-(trifluoromethyl)benzamide::SMR000153151::cid_2123127 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114008&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2123127 252663529 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235145 CC#CCOc1ccc(cc1)S(=O)(=O)CNCC(N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C19H28N4O7S2/c1-3-4-13-30-16-5-7-17(8-6-16)32(28,29)15-20-14-18(19(24)21-25)22-9-11-23(12-10-22)31(2,26)27/h5-8,18,20,25H,9-15H2,1-2H3,(H,21,24) LVXSNFPFOJZOFN-UHFFFAOYSA-N 113573 US8633196, 1::US9365529, 1 Disintegrin and metalloproteinase domain-containing protein 17 87 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113573&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 77014286 199995289 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235146 CC#CCOc1ccc(cc1)S(=O)(=O)NC[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C18H26N4O7S2/c1-3-4-13-29-15-5-7-16(8-6-15)31(27,28)19-14-17(18(23)20-24)21-9-11-22(12-10-21)30(2,25)26/h5-8,17,19,24H,9-14H2,1-2H3,(H,20,23)/t17-/m0/s1 NDILBIRPFZRQSV-KRWDZBQOSA-N 113574 US8633196, 2::US9365529, 2 Disintegrin and metalloproteinase domain-containing protein 17 32 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113574&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849089 199995290 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235147 CS(=O)(=O)N1CCN(CC1)[C@@H](CNCS(=O)(=O)c1ccc(OCc2ccccc2)cc1)C(=O)NO InChI=1S/C22H30N4O7S2/c1-34(29,30)26-13-11-25(12-14-26)21(22(27)24-28)15-23-17-35(31,32)20-9-7-19(8-10-20)33-16-18-5-3-2-4-6-18/h2-10,21,23,28H,11-17H2,1H3,(H,24,27)/t21-/m0/s1 FZUQBSLWAJVSOZ-NRFANRHFSA-N 113576 US8633196, 4::US9365529, 4 Disintegrin and metalloproteinase domain-containing protein 17 497 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113576&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 77014287 199995292 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235148 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C25H31N5O7S2/c1-18-15-19(22-5-3-4-6-23(22)27-18)17-37-20-7-9-21(10-8-20)39(35,36)26-16-24(25(31)28-32)29-11-13-30(14-12-29)38(2,33)34/h3-10,15,24,26,32H,11-14,16-17H2,1-2H3,(H,28,31)/t24-/m0/s1 IVLLKNCAVYHIFI-DEOSSOPVSA-N 113577 US8633196, 14::US8633196, 5::US9365529, 5 Disintegrin and metalloproteinase domain-containing protein 17 21 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849092 199995293 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235149 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cccc3ccccc23)cc1)C(=O)NO InChI=1S/C25H30N4O7S2/c1-37(32,33)29-15-13-28(14-16-29)24(25(30)27-31)17-26-38(34,35)22-11-9-21(10-12-22)36-18-20-7-4-6-19-5-2-3-8-23(19)20/h2-12,24,26,31H,13-18H2,1H3,(H,27,30)/t24-/m0/s1 GMFKQLSOVMGNDE-DEOSSOPVSA-N 113578 US8633196, 6::US9365529, 6 Disintegrin and metalloproteinase domain-containing protein 17 52 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113578&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849198 199995294 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235150 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cccc(c2)C#N)cc1)C(=O)NO InChI=1S/C22H27N5O7S2/c1-35(30,31)27-11-9-26(10-12-27)21(22(28)25-29)15-24-36(32,33)20-7-5-19(6-8-20)34-16-18-4-2-3-17(13-18)14-23/h2-8,13,21,24,29H,9-12,15-16H2,1H3,(H,25,28)/t21-/m0/s1 OIUKNLHRLRYZSP-NRFANRHFSA-N 113580 US8633196, 8::US9365529, 8 Disintegrin and metalloproteinase domain-containing protein 17 127 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113580&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849199 199995296 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235151 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2ccc(cc2)C#N)cc1)C(=O)NO InChI=1S/C22H27N5O7S2/c1-35(30,31)27-12-10-26(11-13-27)21(22(28)25-29)15-24-36(32,33)20-8-6-19(7-9-20)34-16-18-4-2-17(14-23)3-5-18/h2-9,21,24,29H,10-13,15-16H2,1H3,(H,25,28)/t21-/m0/s1 FRTIGTXSRUVYBM-NRFANRHFSA-N 113581 US8633196, 9::US9365529, 9 Disintegrin and metalloproteinase domain-containing protein 17 147 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113581&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849200 199995297 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235152 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(CC2)C(=O)OCc2ccccc2)C(=O)NO)c2ccccc2n1 InChI=1S/C32H35N5O7S/c1-23-19-25(28-9-5-6-10-29(28)34-23)22-43-26-11-13-27(14-12-26)45(41,42)33-20-30(31(38)35-40)36-15-17-37(18-16-36)32(39)44-21-24-7-3-2-4-8-24/h2-14,19,30,33,40H,15-18,20-22H2,1H3,(H,35,38)/t30-/m0/s1 WYQFYOPMZXRDFX-PMERELPUSA-N 113582 US8633196, 10::US9365529, 10 Disintegrin and metalloproteinase domain-containing protein 17 47 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113582&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849201 199995298 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235153 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)C(=O)NO InChI=1S/C26H31N5O7S2/c1-39(34,35)31-15-13-30(14-16-31)25(26(32)29-33)18-28-40(36,37)23-9-7-22(8-10-23)38-19-20-11-12-27-24(17-20)21-5-3-2-4-6-21/h2-12,17,25,28,33H,13-16,18-19H2,1H3,(H,29,32)/t25-/m0/s1 NVTYXFMRFDNMOE-VWLOTQADSA-N 113583 US8633196, 11::US9365529, 11 Disintegrin and metalloproteinase domain-containing protein 17 24 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113583&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849202 199995299 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235154 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCNCC2)C(=O)NO)c2ccccc2n1 InChI=1S/C24H29N5O5S/c1-17-14-18(21-4-2-3-5-22(21)27-17)16-34-19-6-8-20(9-7-19)35(32,33)26-15-23(24(30)28-31)29-12-10-25-11-13-29/h2-9,14,23,25-26,31H,10-13,15-16H2,1H3,(H,28,30)/t23-/m0/s1 NITVPFGZLZEXAL-QHCPKHFHSA-N 113584 US8633196, 13::US9365529, 13 Disintegrin and metalloproteinase domain-containing protein 17 108 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113584&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847348 199995300 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235155 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C25H31N5O7S2/c1-18-15-19(22-5-3-4-6-23(22)27-18)17-37-20-7-9-21(10-8-20)39(35,36)26-16-24(25(31)28-32)29-11-13-30(14-12-29)38(2,33)34/h3-10,15,24,26,32H,11-14,16-17H2,1-2H3,(H,28,31)/t24-/m0/s1 IVLLKNCAVYHIFI-DEOSSOPVSA-N 113577 US8633196, 14::US8633196, 5::US9365529, 5 Disintegrin and metalloproteinase domain-containing protein 17 64 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849092 199995293 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235156 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2ccnc3ccccc23)cc1)C(=O)NO InChI=1S/C24H29N5O7S2/c1-37(32,33)29-14-12-28(13-15-29)23(24(30)27-31)16-26-38(34,35)20-8-6-19(7-9-20)36-17-18-10-11-25-22-5-3-2-4-21(18)22/h2-11,23,26,31H,12-17H2,1H3,(H,27,30)/t23-/m0/s1 YYKOFMPNFHGOJF-QHCPKHFHSA-N 113586 US8633196, 16::US9365529, 16 Disintegrin and metalloproteinase domain-containing protein 17 168 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113586&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847351 199995302 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235157 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccccc3)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C31H35N5O5S/c1-23-19-25(28-9-5-6-10-29(28)33-23)22-41-26-11-13-27(14-12-26)42(39,40)32-20-30(31(37)34-38)36-17-15-35(16-18-36)21-24-7-3-2-4-8-24/h2-14,19,30,32,38H,15-18,20-22H2,1H3,(H,34,37)/t30-/m0/s1 XPGFEPBGGOVQAJ-PMERELPUSA-N 113587 US8633196, 17::US9365529, 17 Disintegrin and metalloproteinase domain-containing protein 17 62 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113587&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847473 199995303 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235158 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(F)cc3)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C31H34FN5O5S/c1-22-18-24(28-4-2-3-5-29(28)34-22)21-42-26-10-12-27(13-11-26)43(40,41)33-19-30(31(38)35-39)37-16-14-36(15-17-37)20-23-6-8-25(32)9-7-23/h2-13,18,30,33,39H,14-17,19-21H2,1H3,(H,35,38)/t30-/m0/s1 UWCNFKCKFSEPKW-PMERELPUSA-N 113588 US8633196, 18::US9365529, 18 Disintegrin and metalloproteinase domain-containing protein 17 67 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113588&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847471 199995304 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235159 CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1 UFNKXVJYCDHZQW-VWLOTQADSA-N 113589 US8633196, 19::US9365529, 19 Disintegrin and metalloproteinase domain-containing protein 17 41 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113589&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847472 199995305 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235160 Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1 OEKBBQNVZPGHFU-HKBQPEDESA-N 113590 US8633196, 21::US9365529, 21 Disintegrin and metalloproteinase domain-containing protein 17 63 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113590&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847597 199995306 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235161 CC(C)C(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C28H35N5O6S/c1-19(2)28(35)33-14-12-32(13-15-33)26(27(34)31-36)17-29-40(37,38)23-10-8-22(9-11-23)39-18-21-16-20(3)30-25-7-5-4-6-24(21)25/h4-11,16,19,26,29,36H,12-15,17-18H2,1-3H3,(H,31,34)/t26-/m0/s1 NVPQXUAYORUQIU-SANMLTNESA-N 113591 US8633196, 23::US9365529, 23 Disintegrin and metalloproteinase domain-containing protein 17 53 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113591&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847599 199995307 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235162 CC(C)CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C28H37N5O7S2/c1-20(2)19-41(36,37)33-14-12-32(13-15-33)27(28(34)31-35)17-29-42(38,39)24-10-8-23(9-11-24)40-18-22-16-21(3)30-26-7-5-4-6-25(22)26/h4-11,16,20,27,29,35H,12-15,17-19H2,1-3H3,(H,31,34)/t27-/m0/s1 IUVIWMVVODOSQU-MHZLTWQESA-N 113592 US8633196, 24::US9365529, 24 Disintegrin and metalloproteinase domain-containing protein 17 86 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113592&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847600 199995308 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235163 CC(C)S(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C27H35N5O7S2/c1-19(2)41(37,38)32-14-12-31(13-15-32)26(27(33)30-34)17-28-40(35,36)23-10-8-22(9-11-23)39-18-21-16-20(3)29-25-7-5-4-6-24(21)25/h4-11,16,19,26,28,34H,12-15,17-18H2,1-3H3,(H,30,33)/t26-/m0/s1 AHKGXKHDKHAJDE-SANMLTNESA-N 113593 US8633196, 26::US9365529, 26 Disintegrin and metalloproteinase domain-containing protein 17 33 7.4 37.00 C US Patent 10.7270/Q2KK99FQ aid1800320 US8633196 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113593&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49837937 199995309 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236243 Cc1cc(Nc2ccc(Cl)cc2)n(n1)-c1cccc(Cl)c1 InChI=1S/C16H13Cl2N3/c1-11-9-16(19-14-7-5-12(17)6-8-14)21(20-11)15-4-2-3-13(18)10-15/h2-10,19H,1H3 VCSUQZLXYTZUSA-UHFFFAOYSA-N 39719 (4-chlorophenyl)-[2-(3-chlorophenyl)-5-methyl-pyrazol-3-yl]amine::2-(3-chlorophenyl)-N-(4-chlorophenyl)-5-methyl-3-pyrazolamine::2-(3-chlorophenyl)-N-(4-chlorophenyl)-5-methyl-pyrazol-3-amine::2-(3-chlorophenyl)-N-(4-chlorophenyl)-5-methylpyrazol-3-amine::MLS000536181::SMR000155520::cid_2408836 Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39719&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2408836 252620605 ZINC03293235 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236244 Cc1nn(Cc2ccccc2Cl)c2sc(cc12)C(=O)NCc1ccc2OCOc2c1 InChI=1S/C22H18ClN3O3S/c1-13-16-9-20(21(27)24-10-14-6-7-18-19(8-14)29-12-28-18)30-22(16)26(25-13)11-15-4-2-3-5-17(15)23/h2-9H,10-12H2,1H3,(H,24,27) CUBSTUYZEQYVEV-UHFFFAOYSA-N 114009 1-(2-chlorobenzyl)-3-methyl-N-piperonyl-thieno[2,3-c]pyrazole-5-carboxamide::MLS000566039::N-(1,3-benzodioxol-5-ylmethyl)-1-[(2-chlorophenyl)methyl]-3-methyl-5-thieno[2,3-c]pyrazolecarboxamide::N-(1,3-benzodioxol-5-ylmethyl)-1-[(2-chlorophenyl)methyl]-3-methyl-thieno[2,3-c]pyrazole-5-carboxamide::N-(1,3-benzodioxol-5-ylmethyl)-1-[(2-chlorophenyl)methyl]-3-methylthieno[2,3-c]pyrazole-5-carboxamide::SMR000153188::cid_4289251 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114009&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4289251 252663530 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236245 Cc1noc(C)c1C(=O)OCC(=O)Nc1ccccc1Oc1ccccc1 InChI=1S/C20H18N2O5/c1-13-19(14(2)27-22-13)20(24)25-12-18(23)21-16-10-6-7-11-17(16)26-15-8-4-3-5-9-15/h3-11H,12H2,1-2H3,(H,21,23) HYWKBVDVMSFWEO-UHFFFAOYSA-N 114010 3,5-dimethyl-4-isoxazolecarboxylic acid [2-oxo-2-(2-phenoxyanilino)ethyl] ester::3,5-dimethylisoxazole-4-carboxylic acid [2-keto-2-(2-phenoxyanilino)ethyl] ester::MLS000567091::SMR000153812::[2-oxidanylidene-2-[(2-phenoxyphenyl)amino]ethyl] 3,5-dimethyl-1,2-oxazole-4-carboxylate::[2-oxo-2-(2-phenoxyanilino)ethyl] 3,5-dimethyl-1,2-oxazole-4-carboxylate::cid_2480772 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114010&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2480772 252663531 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236246 Nc1cc(Cl)ccc1Oc1ccc2ccccc2c1 InChI=1S/C16H12ClNO/c17-13-6-8-16(15(18)10-13)19-14-7-5-11-3-1-2-4-12(11)9-14/h1-10H,18H2 OSONOOMSGZJDBA-UHFFFAOYSA-N 78105 5-chloranyl-2-naphthalen-2-yloxy-aniline::5-chloro-2-(2-naphthalenyloxy)aniline::5-chloro-2-naphthalen-2-yloxyaniline::MLS000564927::SMR000152168::[5-chloro-2-(2-naphthoxy)phenyl]amine::cid_2337866 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78105&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2337866 252654867 ZINC03219176 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236247 COc1ccc(OC)c(NC(=O)COC(=O)c2c3CCCCc3nc3ccccc23)c1 InChI=1S/C24H24N2O5/c1-29-15-11-12-21(30-2)20(13-15)26-22(27)14-31-24(28)23-16-7-3-5-9-18(16)25-19-10-6-4-8-17(19)23/h3,5,7,9,11-13H,4,6,8,10,14H2,1-2H3,(H,26,27) HHAZCSMPBQWFJO-UHFFFAOYSA-N 114011 1,2,3,4-tetrahydroacridine-9-carboxylic acid [2-(2,5-dimethoxyanilino)-2-keto-ethyl] ester::1,2,3,4-tetrahydroacridine-9-carboxylic acid [2-(2,5-dimethoxyanilino)-2-oxoethyl] ester::MLS000564951::SMR000152210::[2-(2,5-dimethoxyanilino)-2-oxoethyl] 1,2,3,4-tetrahydroacridine-9-carboxylate::[2-[(2,5-dimethoxyphenyl)amino]-2-oxidanylidene-ethyl] 1,2,3,4-tetrahydroacridine-9-carboxylate::cid_2356130 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114011&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2356130 252663532 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236248 Cc1ccc(cc1)-n1c(n[nH]c1=S)C1CC1c1ccc(Cl)cc1 InChI=1S/C18H16ClN3S/c1-11-2-8-14(9-3-11)22-17(20-21-18(22)23)16-10-15(16)12-4-6-13(19)7-5-12/h2-9,15-16H,10H2,1H3,(H,21,23) RHXMARFAJZENTK-UHFFFAOYSA-N 95903 3-[2-(4-chlorophenyl)cyclopropyl]-4-(4-methylphenyl)-1H-1,2,4-triazole-5-thione::3-[2-(4-chlorophenyl)cyclopropyl]-4-(p-tolyl)-1H-1,2,4-triazole-5-thione::5-[2-(4-chlorophenyl)cyclopropyl]-4-(4-methylphenyl)-4H-1,2,4-triazol-3-yl hydrosulfide::MLS000538672::SMR000160285::cid_4744972 Disintegrin and metalloproteinase domain-containing protein 17 69548 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95903&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4744972 164037147 ZINC06533870 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236249 Clc1ccc(NC(C2CCCCC2=O)c2ccccc2)cc1 InChI=1S/C19H20ClNO/c20-15-10-12-16(13-11-15)21-19(14-6-2-1-3-7-14)17-8-4-5-9-18(17)22/h1-3,6-7,10-13,17,19,21H,4-5,8-9H2 OIDUARCVRKPECP-UHFFFAOYSA-N 114012 2-[(4-chloroanilino)(phenyl)methyl]cyclohexanone::2-[(4-chloroanilino)-phenyl-methyl]cyclohexanone::2-[(4-chloroanilino)-phenylmethyl]-1-cyclohexanone::2-[(4-chloroanilino)-phenylmethyl]cyclohexan-1-one::2-[[(4-chlorophenyl)amino]-phenyl-methyl]cyclohexan-1-one::MLS000537189::SMR000161708::cid_11012459 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114012&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11012459 252663533 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236250 CCOC(=O)c1c(C)c(C)sc1NC(=O)Cn1nc(cc1C(F)F)C(F)F InChI=1S/C16H17F4N3O3S/c1-4-26-16(25)12-7(2)8(3)27-15(12)21-11(24)6-23-10(14(19)20)5-9(22-23)13(17)18/h5,13-14H,4,6H2,1-3H3,(H,21,24) IOCQCVHYCAZARR-UHFFFAOYSA-N 114013 2-[[2-[3,5-bis(difluoromethyl)-1-pyrazolyl]-1-oxoethyl]amino]-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester::2-[[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]amino]-4,5-dimethyl-thiophene-3-carboxylic acid ethyl ester::MLS000544419::SMR000159953::cid_996760::ethyl 2-({[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}amino)-4,5-dimethyl-3-thiophenecarboxylate::ethyl 2-[2-[3,5-bis[bis(fluoranyl)methyl]pyrazol-1-yl]ethanoylamino]-4,5-dimethyl-thiophene-3-carboxylate::ethyl 2-[[2-[3,5-bis(difluoromethyl)pyrazol-1-yl]acetyl]amino]-4,5-dimethylthiophene-3-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114013&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 996760 252663534 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236251 Clc1ccc(cc1)C1N(CCc2c1[nH]c1ccccc21)C(=O)c1cccs1 InChI=1S/C22H17ClN2OS/c23-15-9-7-14(8-10-15)21-20-17(16-4-1-2-5-18(16)24-20)11-12-25(21)22(26)19-6-3-13-27-19/h1-10,13,21,24H,11-12H2 XGIUNRTXJGFTJI-UHFFFAOYSA-N 113845 1-(4-chlorophenyl)-2-(2-thienylcarbonyl)-2,3,4,9-tetrahydro-1H-beta-carboline::MLS000544536::SMR000159578::[1-(4-chlorophenyl)-1,3,4,9-tetrahydro-beta-carbolin-2-yl]-(2-thienyl)methanone::[1-(4-chlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-thiophen-2-yl-methanone::[1-(4-chlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-thiophen-2-ylmethanone::cid_3610662 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113845&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3610662 252663376 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236252 COc1ccc(NC(C)C(=O)N\N=C\c2ccccc2OCc2ccc(Br)cc2)cc1 InChI=1S/C24H24BrN3O3/c1-17(27-21-11-13-22(30-2)14-12-21)24(29)28-26-15-19-5-3-4-6-23(19)31-16-18-7-9-20(25)10-8-18/h3-15,17,27H,16H2,1-2H3,(H,28,29)/b26-15+ WALADQCSKJDDDG-CVKSISIWSA-N 114014 MLS000543476::N'-{2-[(4-bromobenzyl)oxy]benzylidene}-2-(4-methoxyanilino)propanohydrazide::N-[(E)-[2-(4-bromobenzyl)oxybenzylidene]amino]-2-(p-anisidino)propionamide::N-[(E)-[2-[(4-bromophenyl)methoxy]phenyl]methylideneamino]-2-(4-methoxyanilino)propanamide::N-[(E)-[2-[(4-bromophenyl)methoxy]phenyl]methylideneamino]-2-[(4-methoxyphenyl)amino]propanamide::SMR000159628::cid_9654062 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114014&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9654062 252663535 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236253 CC(Nc1ccccc1C)C(=O)N\N=C\c1ccccc1OCc1cccc(Br)c1 InChI=1S/C24H24BrN3O2/c1-17-8-3-5-12-22(17)27-18(2)24(29)28-26-15-20-10-4-6-13-23(20)30-16-19-9-7-11-21(25)14-19/h3-15,18,27H,16H2,1-2H3,(H,28,29)/b26-15+ GLMVTVQTPRBKPQ-CVKSISIWSA-N 113847 MLS000544324::N'-{2-[(3-bromobenzyl)oxy]benzylidene}-2-(2-toluidino)propanohydrazide::N-[(E)-[2-(3-bromobenzyl)oxybenzylidene]amino]-2-(o-toluidino)propionamide::N-[(E)-[2-[(3-bromophenyl)methoxy]phenyl]methylideneamino]-2-(2-methylanilino)propanamide::N-[(E)-[2-[(3-bromophenyl)methoxy]phenyl]methylideneamino]-2-[(2-methylphenyl)amino]propanamide::SMR000159646::cid_9620252 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113847&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9620252 252663378 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236254 Clc1ccc(SCC(=O)N2CCC(CC2)c2nc3ccccc3s2)c(Cl)c1 InChI=1S/C20H18Cl2N2OS2/c21-14-5-6-17(15(22)11-14)26-12-19(25)24-9-7-13(8-10-24)20-23-16-3-1-2-4-18(16)27-20/h1-6,11,13H,7-10,12H2 YEMNHTMAEPPCQS-UHFFFAOYSA-N 113848 1-[4-(1,3-benzothiazol-2-yl)-1-piperidinyl]-2-[(2,4-dichlorophenyl)thio]ethanone::1-[4-(1,3-benzothiazol-2-yl)piperidin-1-yl]-2-(2,4-dichlorophenyl)sulfanyl-ethanone::1-[4-(1,3-benzothiazol-2-yl)piperidin-1-yl]-2-(2,4-dichlorophenyl)sulfanylethanone::1-[4-(1,3-benzothiazol-2-yl)piperidino]-2-[(2,4-dichlorophenyl)sulfanyl]-1-ethanone::1-[4-(1,3-benzothiazol-2-yl)piperidino]-2-[(2,4-dichlorophenyl)thio]ethanone::MLS000326867::SMR000179502::cid_1479989 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113848&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1479989 252663379 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236255 Cc1cccc(Oc2cc(NC(=O)c3ccccc3)cc(c2)[N+]([O-])=O)c1 InChI=1S/C20H16N2O4/c1-14-6-5-9-18(10-14)26-19-12-16(11-17(13-19)22(24)25)21-20(23)15-7-3-2-4-8-15/h2-13H,1H3,(H,21,23) XTHCAVSROMSUQZ-UHFFFAOYSA-N 78128 MLS000562229::N-(3-Nitro-5-m-tolyloxy-phenyl)-benzamide::N-[3-(3-methylphenoxy)-5-nitro-phenyl]benzamide::N-[3-(3-methylphenoxy)-5-nitrophenyl]benzamide::SMR000175060::cid_771884 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=78128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=78128&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 771884 252654890 ZINC00255382 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236256 CCOc1cc(ccc1O)C(c1c(C)[nH][nH]c1=O)c1c(C)[nH][nH]c1=O InChI=1S/C17H20N4O4/c1-4-25-12-7-10(5-6-11(12)22)15(13-8(2)18-20-16(13)23)14-9(3)19-21-17(14)24/h5-7,15,22H,4H2,1-3H3,(H2,18,20,23)(H2,19,21,24) ADJJHTKFPPOEAH-UHFFFAOYSA-N 52423 4-[(3-ethoxy-4-hydroxy-phenyl)-(3-keto-5-methyl-3-pyrazolin-4-yl)methyl]-5-methyl-3-pyrazolin-3-one::4-[(3-ethoxy-4-hydroxyphenyl)-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one::4-[(3-ethoxy-4-oxidanyl-phenyl)-(3-methyl-5-oxidanylidene-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one::MLS000548777::SMR000172333::cid_3154563 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52423 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52423&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3154563 252632566 ZINC13478186 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236257 Cc1ccc(NC(=O)NNC(=O)Cn2nc(-c3ccccc3)c(-c3ccccc3)c(C#N)c2=O)cc1 InChI=1S/C27H22N6O3/c1-18-12-14-21(15-13-18)29-27(36)31-30-23(34)17-33-26(35)22(16-28)24(19-8-4-2-5-9-19)25(32-33)20-10-6-3-7-11-20/h2-15H,17H2,1H3,(H,30,34)(H2,29,31,36) DQGNGNICUPBOQI-UHFFFAOYSA-N 114015 1-[2-(5-cyano-6-oxidanylidene-3,4-diphenyl-pyridazin-1-yl)ethanoylamino]-3-(4-methylphenyl)urea::1-[[2-(5-cyano-6-keto-3,4-diphenyl-pyridazin-1-yl)acetyl]amino]-3-(p-tolyl)urea::1-[[2-(5-cyano-6-oxo-3,4-diphenyl-1-pyridazinyl)-1-oxoethyl]amino]-3-(4-methylphenyl)urea::1-[[2-(5-cyano-6-oxo-3,4-diphenylpyridazin-1-yl)acetyl]amino]-3-(4-methylphenyl)urea::2-[(5-cyano-6-oxo-3,4-diphenyl-1(6H)-pyridazinyl)acetyl]-N-(4-methylphenyl)hydrazinecarboxamide::MLS000545077::SMR000161287::cid_990304 Disintegrin and metalloproteinase domain-containing protein 17 69495 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114015&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 990304 252663536 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236258 Cc1cc(C)n(Cc2ccc(NC(=O)c3ccc(COc4ccccc4Br)cc3)cc2)n1 InChI=1S/C26H24BrN3O2/c1-18-15-19(2)30(29-18)16-20-9-13-23(14-10-20)28-26(31)22-11-7-21(8-12-22)17-32-25-6-4-3-5-24(25)27/h3-15H,16-17H2,1-2H3,(H,28,31) LSIJVGVQXDFLSS-UHFFFAOYSA-N 46386 4-[(2-bromanylphenoxy)methyl]-N-[4-[(3,5-dimethylpyrazol-1-yl)methyl]phenyl]benzamide::4-[(2-bromophenoxy)methyl]-N-[4-[(3,5-dimethyl-1-pyrazolyl)methyl]phenyl]benzamide::4-[(2-bromophenoxy)methyl]-N-[4-[(3,5-dimethylpyrazol-1-yl)methyl]phenyl]benzamide::4-[(2-bromophenoxy)methyl]-N-{4-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]phenyl}benzamide::MLS000544434::SMR000160010::cid_997451 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=46386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=46386&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 997451 252626945 ZINC00651347 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236259 Cc1cccc(c1)C(N)=NOC(=O)N1CCOCC1 InChI=1S/C13H17N3O3/c1-10-3-2-4-11(9-10)12(14)15-19-13(17)16-5-7-18-8-6-16/h2-4,9H,5-8H2,1H3,(H2,14,15) ZLSARIVSSBFFOK-UHFFFAOYSA-N 114016 4-morpholinecarboxylic acid [(Z)-[amino-(3-methylphenyl)methylidene]amino] ester::MLS000558347::SMR000178370::[(Z)-[amino-(3-methylphenyl)methylidene]amino] morpholine-4-carboxylate::[(Z)-[azanyl-(3-methylphenyl)methylidene]amino] morpholine-4-carboxylate::cid_9587468::morpholine-4-carboxylic acid [(Z)-[amino(m-tolyl)methylene]amino] ester Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114016&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9587468 252663537 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236260 CCOc1ccc(cc1)N=Nc1c2[nH]c(C)cc(=O)n2[nH]c1=O InChI=1S/C15H15N5O3/c1-3-23-11-6-4-10(5-7-11)17-18-13-14-16-9(2)8-12(21)20(14)19-15(13)22/h4-8,16H,3H2,1-2H3,(H,19,22) WLZJRJPXYRHPRM-UHFFFAOYSA-N 53389 (3E)-5-methyl-3-(p-phenetylhydrazono)-1H-pyrazolo[1,5-a]pyrimidine-2,7-quinone::3-[(4-ethoxyphenyl)diazenyl]-5-methylpyrazolo[1,5-a]pyrimidine-2,7(1H,4H)-dione::3-[(4-ethoxyphenyl)hydrazinylidene]-5-methyl-1H-pyrazolo[1,5-a]pyrimidine-2,7-dione::5-methyl-3-(p-phenetylhydrazono)-1H-pyrazolo[1,5-a]pyrimidine-2,7-quinone::MLS000325272::SMR000161346::cid_7309410 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53389&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 40783946 252633520 ZINC01048856 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236261 Clc1ncc(COC(=O)c2cccc(Cl)c2Cl)s1 InChI=1S/C11H6Cl3NO2S/c12-8-3-1-2-7(9(8)13)10(16)17-5-6-4-15-11(14)18-6/h1-4H,5H2 HHAXGYKWAMWSJK-UHFFFAOYSA-N 114018 (2-chloranyl-1,3-thiazol-5-yl)methyl 2,3-bis(chloranyl)benzoate::(2-chloro-1,3-thiazol-5-yl)methyl 2,3-dichlorobenzenecarboxylate::(2-chloro-1,3-thiazol-5-yl)methyl 2,3-dichlorobenzoate::2,3-dichlorobenzoic acid (2-chloro-5-thiazolyl)methyl ester::2,3-dichlorobenzoic acid (2-chlorothiazol-5-yl)methyl ester::MLS000326731::SMR000179239::cid_1479767 Disintegrin and metalloproteinase domain-containing protein 17 69569 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114018&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1479767 252663538 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236262 CC(Oc1ccc(Cl)cc1)c1ccnn1S(=O)(=O)c1ccccc1 InChI=1S/C17H15ClN2O3S/c1-13(23-15-9-7-14(18)8-10-15)17-11-12-19-20(17)24(21,22)16-5-3-2-4-6-16/h2-13H,1H3 ASRGVRPSBKQXAR-UHFFFAOYSA-N 114019 1-(benzenesulfonyl)-5-[1-(4-chlorophenoxy)ethyl]pyrazole::1-besyl-5-[1-(4-chlorophenoxy)ethyl]pyrazole::4-chlorophenyl 1-[1-(phenylsulfonyl)-1H-pyrazol-5-yl]ethyl ether::5-[1-(4-chloranylphenoxy)ethyl]-1-(phenylsulfonyl)pyrazole::MLS000327909::SMR000168441::cid_3799510 Disintegrin and metalloproteinase domain-containing protein 17 69497 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114019&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3799510 252663539 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236263 O=C(Nc1cccc2ccccc12)c1ccc(OC(=S)N2CCOCC2)cc1 InChI=1S/C22H20N2O3S/c25-21(23-20-7-3-5-16-4-1-2-6-19(16)20)17-8-10-18(11-9-17)27-22(28)24-12-14-26-15-13-24/h1-11H,12-15H2,(H,23,25) JHNJNFUPEGBKKY-UHFFFAOYSA-N 114020 4-morpholinecarbothioic acid O-[4-[(1-naphthalenylamino)-oxomethyl]phenyl] ester::MLS000579078::O-[4-(naphthalen-1-ylcarbamoyl)phenyl] morpholine-4-carbothioate::O-{4-[(1-naphthylamino)carbonyl]phenyl} 4-morpholinecarbothioate::SMR000186667::cid_1354484::morpholine-4-carbothioic acid O-[4-(1-naphthylcarbamoyl)phenyl] ester Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114020&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1354484 252663540 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236264 OC(CN(c1ccccc1)S(=O)(=O)c1ccccc1)Cn1c2ccccc2c2ccccc12 InChI=1S/C27H24N2O3S/c30-22(19-28-26-17-9-7-15-24(26)25-16-8-10-18-27(25)28)20-29(21-11-3-1-4-12-21)33(31,32)23-13-5-2-6-14-23/h1-18,22,30H,19-20H2 XXXXUNMGBLAEHU-UHFFFAOYSA-N 114021 MLS000574307::N-(3-carbazol-9-yl-2-hydroxy-propyl)-N-phenyl-benzenesulfonamide::N-(3-carbazol-9-yl-2-hydroxypropyl)-N-phenylbenzenesulfonamide::N-(3-carbazol-9-yl-2-oxidanyl-propyl)-N-phenyl-benzenesulfonamide::N-[3-(9-carbazolyl)-2-hydroxypropyl]-N-phenylbenzenesulfonamide::N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-phenylbenzenesulfonamide::SMR000195898::cid_2908418 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2908418 252663541 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236265 CC(=NNC(=N)Sc1cc(O)n(c1O)-c1ccc(Br)cc1)c1cccs1 InChI=1S/C17H15BrN4O2S2/c1-10(13-3-2-8-25-13)20-21-17(19)26-14-9-15(23)22(16(14)24)12-6-4-11(18)5-7-12/h2-9,23-24H,1H3,(H2,19,21) BHMVHMSAJIFURV-UHFFFAOYSA-N 57407 1-(4-bromophenyl)-2,5-dioxo-3-pyrrolidinyl 2-[1-(2-thienyl)ethylidene]hydrazinecarbimidothioate::2-[1-(4-bromophenyl)-2,5-diketo-pyrrolidin-3-yl]-3-[(E)-1-(2-thienyl)ethylideneamino]isothiourea::2-[1-(4-bromophenyl)-2,5-diketo-pyrrolidin-3-yl]-3-[1-(2-thienyl)ethylideneamino]isothiourea::MLS000579154::N''-(1-thiophen-2-ylethylideneamino)carbamimidothioic acid [1-(4-bromophenyl)-2,5-dioxo-3-pyrrolidinyl] ester::SMR000186742::[1-(4-bromophenyl)-2,5-bis(oxidanylidene)pyrrolidin-3-yl] N''-(1-thiophen-2-ylethylideneamino)carbamimidothioate::[1-(4-bromophenyl)-2,5-dioxopyrrolidin-3-yl] N''-(1-thiophen-2-ylethylideneamino)carbamimidothioate::cid_2859642 Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57407&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91897303 252637337 ZINC17723403 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236266 CC(=NNC(=N)Sc1cc(O)n(c1O)-c1ccccc1)c1cccs1 InChI=1S/C17H16N4O2S2/c1-11(13-8-5-9-24-13)19-20-17(18)25-14-10-15(22)21(16(14)23)12-6-3-2-4-7-12/h2-10,22-23H,1H3,(H2,18,20) QOWRHSBGMQKKSY-UHFFFAOYSA-N 114023 (2,5-dioxo-1-phenylpyrrolidin-3-yl) N'-[(E)-1-thiophen-2-ylethylideneamino]carbamimidothioate::2,5-dioxo-1-phenyl-3-pyrrolidinyl 2-[1-(2-thienyl)ethylidene]hydrazinecarbimidothioate::2-(2,5-diketo-1-phenyl-pyrrolidin-3-yl)-3-[(E)-1-(2-thienyl)ethylideneamino]isothiourea::MLS000579121::N'-[(E)-1-thiophen-2-ylethylideneamino]carbamimidothioic acid (2,5-dioxo-1-phenyl-3-pyrrolidinyl) ester::SMR000186710::[2,5-bis(oxidanylidene)-1-phenyl-pyrrolidin-3-yl] N'-[(E)-1-thiophen-2-ylethylideneamino]carbamimidothioate::cid_9566953 Disintegrin and metalloproteinase domain-containing protein 17 69503 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114023&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899705 252663542 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236267 O=C(NC(=S)Nc1ccc2OCCOc2c1)c1cccc2ccccc12 InChI=1S/C20H16N2O3S/c23-19(16-7-3-5-13-4-1-2-6-15(13)16)22-20(26)21-14-8-9-17-18(12-14)25-11-10-24-17/h1-9,12H,10-11H2,(H2,21,22,23,26) RRQWBBSTNXXMAE-UHFFFAOYSA-N 114024 MLS000575314::N-(2,3-dihydro-1,4-benzodioxin-6-ylcarbamothioyl)naphthalene-1-carboxamide::N-(2,3-dihydro-1,4-benzodioxin-6-ylthiocarbamoyl)-1-naphthamide::N-[(2,3-dihydro-1,4-benzodioxin-6-ylamino)-sulfanylidenemethyl]-1-naphthalenecarboxamide::N-[(2,3-dihydro-1,4-benzodioxin-6-ylamino)carbonothioyl]-1-naphthamide::SMR000196548::cid_1048275 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114024&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1048275 252663543 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236268 COc1ccc(cc1)N(CC(O)Cn1c2ccccc2c2ccccc12)S(=O)(=O)c1ccccc1 InChI=1S/C28H26N2O4S/c1-34-23-17-15-21(16-18-23)30(35(32,33)24-9-3-2-4-10-24)20-22(31)19-29-27-13-7-5-11-25(27)26-12-6-8-14-28(26)29/h2-18,22,31H,19-20H2,1H3 RVKMFYITESTEIC-UHFFFAOYSA-N 113861 MLS000574276::N-(3-carbazol-9-yl-2-hydroxy-propyl)-N-(4-methoxyphenyl)benzenesulfonamide::N-(3-carbazol-9-yl-2-hydroxypropyl)-N-(4-methoxyphenyl)benzenesulfonamide::N-(3-carbazol-9-yl-2-oxidanyl-propyl)-N-(4-methoxyphenyl)benzenesulfonamide::N-[3-(9-carbazolyl)-2-hydroxypropyl]-N-(4-methoxyphenyl)benzenesulfonamide::N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(4-methoxyphenyl)benzenesulfonamide::SMR000195867::cid_2908002 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113861&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2908002 252663392 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236269 S=c1[nH]nc(C2CCCCC2)n1N=CC=Cc1ccccc1 InChI=1S/C17H20N4S/c22-17-20-19-16(15-11-5-2-6-12-15)21(17)18-13-7-10-14-8-3-1-4-9-14/h1,3-4,7-10,13,15H,2,5-6,11-12H2,(H,20,22)/b10-7+,18-13+ VCVALGNZBFXITM-CVUDBVLYSA-N 67948 3-cyclohexyl-4-[(E)-[(E)-3-phenylprop-2-enylidene]amino]-1H-1,2,4-triazole-5-thione::3-cyclohexyl-4-[[(E)-3-phenylprop-2-enylidene]amino]-1H-1,2,4-triazole-5-thione::5-cyclohexyl-4-[(3-phenyl-2-propen-1-ylidene)amino]-4H-1,2,4-triazole-3-thiol::MLS000577246::SMR000197354::cid_1955243 Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67948&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6886596 252646228 ZINC15979112 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236270 Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc1ccc2CCc3cccc1c23 InChI=1S/C21H21NO2S/c1-13-11-14(2)21(15(3)12-13)25(23,24)22-19-10-9-17-8-7-16-5-4-6-18(19)20(16)17/h4-6,9-12,22H,7-8H2,1-3H3 IEWFLISZFADZRD-UHFFFAOYSA-N 114026 MLS000580606::N-(1,2-dihydro-5-acenaphthylenyl)-2,4,6-trimethylbenzenesulfonamide::N-(1,2-dihydroacenaphthylen-5-yl)-2,4,6-trimethyl-benzenesulfonamide::N-(1,2-dihydroacenaphthylen-5-yl)-2,4,6-trimethylbenzenesulfonamide::N-acenaphthen-5-yl-2,4,6-trimethyl-benzenesulfonamide::SMR000199495::cid_1290765 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114026&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1290765 252663544 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236271 CC(=O)Oc1ccc(cc1)C(=O)Nc1cccc(c1)C(=O)c1ccc(C)c(C)c1 InChI=1S/C24H21NO4/c1-15-7-8-20(13-16(15)2)23(27)19-5-4-6-21(14-19)25-24(28)18-9-11-22(12-10-18)29-17(3)26/h4-14H,1-3H3,(H,25,28) GWVXJTDIDQMXKZ-UHFFFAOYSA-N 114027 4-({[3-(3,4-dimethylbenzoyl)phenyl]amino}carbonyl)phenyl acetate::MLS000576556::SMR000185941::[4-[[3-(3,4-dimethylbenzoyl)phenyl]carbamoyl]phenyl] acetate::[4-[[3-(3,4-dimethylphenyl)carbonylphenyl]carbamoyl]phenyl] ethanoate::acetic acid [4-[[3-(3,4-dimethylbenzoyl)phenyl]carbamoyl]phenyl] ester::acetic acid [4-[[3-[(3,4-dimethylphenyl)-oxomethyl]anilino]-oxomethyl]phenyl] ester::cid_1369526 Disintegrin and metalloproteinase domain-containing protein 17 69503 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114027&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1369526 252663545 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236272 CCc1cc(C(=O)OC)c(NC(=O)C2CC(=O)NN2Cc2ccccc2)s1 InChI=1S/C19H21N3O4S/c1-3-13-9-14(19(25)26-2)18(27-13)20-17(24)15-10-16(23)21-22(15)11-12-7-5-4-6-8-12/h4-9,15H,3,10-11H2,1-2H3,(H,20,24)(H,21,23) SJTWRSKSTPTTPG-UHFFFAOYSA-N 114028 2-[(2-benzyl-5-keto-pyrazolidine-3-carbonyl)amino]-5-ethyl-thiophene-3-carboxylic acid methyl ester::5-ethyl-2-[[oxo-[5-oxo-2-(phenylmethyl)-3-pyrazolidinyl]methyl]amino]-3-thiophenecarboxylic acid methyl ester::MLS000581923::SMR000200531::cid_2963459::methyl 2-[(2-benzyl-5-oxopyrazolidine-3-carbonyl)amino]-5-ethylthiophene-3-carboxylate::methyl 2-{[(2-benzyl-5-oxo-3-pyrazolidinyl)carbonyl]amino}-5-ethyl-3-thiophenecarboxylate::methyl 5-ethyl-2-[[5-oxidanylidene-2-(phenylmethyl)pyrazolidin-3-yl]carbonylamino]thiophene-3-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114028&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2963459 252663546 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236273 COc1ccc(CN(C(C(=O)NC2CCCC2)c2ccc(C)cc2)C(=O)c2nsc(Cl)c2Cl)cc1 InChI=1S/C26H27Cl2N3O3S/c1-16-7-11-18(12-8-16)23(25(32)29-19-5-3-4-6-19)31(15-17-9-13-20(34-2)14-10-17)26(33)22-21(27)24(28)35-30-22/h7-14,19,23H,3-6,15H2,1-2H3,(H,29,32) RCOHHBZBGOVPHT-UHFFFAOYSA-N 114029 4,5-Dichloro-isothiazole-3-carboxylic acid (cyclopentylcarbamoyl-p-tolyl-methyl)-(4-methoxy-benzyl)-amide::4,5-bis(chloranyl)-N-[2-(cyclopentylamino)-1-(4-methylphenyl)-2-oxidanylidene-ethyl]-N-[(4-methoxyphenyl)methyl]-1,2-thiazole-3-carboxamide::4,5-dichloro-N-[2-(cyclopentylamino)-1-(4-methylphenyl)-2-oxoethyl]-N-[(4-methoxyphenyl)methyl]-1,2-thiazole-3-carboxamide::4,5-dichloro-N-[2-(cyclopentylamino)-1-(4-methylphenyl)-2-oxoethyl]-N-[(4-methoxyphenyl)methyl]-3-isothiazolecarboxamide::4,5-dichloro-N-[2-(cyclopentylamino)-2-keto-1-(p-tolyl)ethyl]-N-p-anisyl-isothiazole-3-carboxamide::MLS000551850::SMR000173029::cid_3197170 Disintegrin and metalloproteinase domain-containing protein 17 69510 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114029&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3197170 252663547 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236274 Cc1ccc(OCCOCCOc2ccc(Br)cc2\C=N/NC(=O)c2ccncc2)cc1 InChI=1S/C24H24BrN3O4/c1-18-2-5-22(6-3-18)31-14-12-30-13-15-32-23-7-4-21(25)16-20(23)17-27-28-24(29)19-8-10-26-11-9-19/h2-11,16-17H,12-15H2,1H3,(H,28,29)/b27-17- VVRABTICHFKFRA-PKAZHMFMSA-N 114030 MLS000571720::N'-(5-bromo-2-{2-[2-(4-methylphenoxy)ethoxy]ethoxy}benzylidene)isonicotinohydrazide::N-[(Z)-[5-bromanyl-2-[2-[2-(4-methylphenoxy)ethoxy]ethoxy]phenyl]methylideneamino]pyridine-4-carboxamide::N-[(Z)-[5-bromo-2-[2-[2-(4-methylphenoxy)ethoxy]ethoxy]benzylidene]amino]isonicotinamide::N-[(Z)-[5-bromo-2-[2-[2-(4-methylphenoxy)ethoxy]ethoxy]phenyl]methylideneamino]-4-pyridinecarboxamide::N-[(Z)-[5-bromo-2-[2-[2-(4-methylphenoxy)ethoxy]ethoxy]phenyl]methylideneamino]pyridine-4-carboxamide::SMR000193732::cid_5345341 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114030&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5345341 252663548 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236275 Clc1ccc(OCCOCCOc2cccc3cccnc23)c(Br)c1 InChI=1S/C19H17BrClNO3/c20-16-13-15(21)6-7-17(16)24-11-9-23-10-12-25-18-5-1-3-14-4-2-8-22-19(14)18/h1-8,13H,9-12H2 PKEWSUMWMHHKLB-UHFFFAOYSA-N 114031 8-[2-[2-(2-bromanyl-4-chloranyl-phenoxy)ethoxy]ethoxy]quinoline::8-[2-[2-(2-bromo-4-chloro-phenoxy)ethoxy]ethoxy]quinoline::8-[2-[2-(2-bromo-4-chlorophenoxy)ethoxy]ethoxy]quinoline::8-{2-[2-(2-bromo-4-chlorophenoxy)ethoxy]ethoxy}quinoline::MLS000574458::SMR000195122::cid_2284155 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114031&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2284155 252663549 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236276 Cc1ccc(cc1)S(=O)(=O)N(Cc1ccc(Cl)cc1)c1ccccc1C(=O)NCc1ccco1 InChI=1S/C26H23ClN2O4S/c1-19-8-14-23(15-9-19)34(31,32)29(18-20-10-12-21(27)13-11-20)25-7-3-2-6-24(25)26(30)28-17-22-5-4-16-33-22/h2-16H,17-18H2,1H3,(H,28,30) JMRLNFAMJMGKAM-UHFFFAOYSA-N 61048 2-[(4-chlorobenzyl)-tosyl-amino]-N-(2-furfuryl)benzamide::2-[(4-chlorophenyl)methyl-(4-methylphenyl)sulfonyl-amino]-N-(furan-2-ylmethyl)benzamide::2-[(4-chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-(2-furanylmethyl)benzamide::2-[(4-chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-(furan-2-ylmethyl)benzamide::2-{(4-chlorobenzyl)[(4-methylphenyl)sulfonyl]amino}-N-(2-furylmethyl)benzamide::MLS000580076::SMR000199320::cid_1287570 Disintegrin and metalloproteinase domain-containing protein 17 69490 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61048&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1287570 252640212 ZINC01108774 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236277 COC(=O)c1cccc(Cn2c(Cl)c(CN=Nc3ccccc3C)sc2=O)c1 InChI=1S/C20H18ClN3O3S/c1-13-6-3-4-9-16(13)23-22-11-17-18(21)24(20(26)28-17)12-14-7-5-8-15(10-14)19(25)27-2/h3-10H,11-12H2,1-2H3 ZDDMHKWBTJKLLE-UHFFFAOYSA-N 72166 3-[4-Chloro-2-oxo-5-(o-tolyl-hydrazonomethyl)-thiazol-3-ylmethyl]-benzoic acid methyl ester::3-[[4-chloro-2-keto-5-[(E)-(o-tolylhydrazono)methyl]-4-thiazolin-3-yl]methyl]benzoic acid methyl ester::3-[[4-chloro-2-keto-5-[(o-tolylhydrazono)methyl]-4-thiazolin-3-yl]methyl]benzoic acid methyl ester::3-[[4-chloro-5-[[(2-methylphenyl)hydrazinylidene]methyl]-2-oxo-3-thiazolyl]methyl]benzoic acid methyl ester::MLS000589672::SMR000219473::cid_4271960::methyl 3-[[4-chloranyl-5-[[(2-methylphenyl)hydrazinylidene]methyl]-2-oxidanylidene-1,3-thiazol-3-yl]methyl]benzoate::methyl 3-[[4-chloro-5-[[(2-methylphenyl)hydrazinylidene]methyl]-2-oxo-1,3-thiazol-3-yl]methyl]benzoate Disintegrin and metalloproteinase domain-containing protein 17 69495 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72166&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91898014 252649429 ZINC13138743 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236278 COc1ccccc1NC(=S)NN=Cc1c[nH]c2ccc(cc12)S(=O)(=O)N1CCCCC1 InChI=1S/C22H25N5O3S2/c1-30-21-8-4-3-7-20(21)25-22(31)26-24-15-16-14-23-19-10-9-17(13-18(16)19)32(28,29)27-11-5-2-6-12-27/h3-4,7-10,13-15,23H,2,5-6,11-12H2,1H3,(H2,25,26,31)/b24-15+ VWSDHWLEPIAZBT-BUVRLJJBSA-N 84075 1-(2-methoxyphenyl)-3-[[(Z)-(5-piperidin-1-ylsulfonylindol-3-ylidene)methyl]amino]thiourea::1-(2-methoxyphenyl)-3-[[(Z)-(5-piperidinosulfonylindol-3-ylidene)methyl]amino]thiourea::1-(2-methoxyphenyl)-3-[[(Z)-[5-(1-piperidinylsulfonyl)-3-indolylidene]methyl]amino]thiourea::MLS-0454628.0002::cid_12004466 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84075&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12004466 252659239 ZINC15974337 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236279 CCC(N1C(=S)S\C(=C/c2cccn2C)C1=O)C(O)=O InChI=1S/C13H14N2O3S2/c1-3-9(12(17)18)15-11(16)10(20-13(15)19)7-8-5-4-6-14(8)2/h4-7,9H,3H2,1-2H3,(H,17,18)/b10-7- XTGUPMZDWXYAEP-YFHOEESVSA-N 79676 2-[(5Z)-4-keto-5-[(1-methylpyrrol-2-yl)methylene]-2-thioxo-thiazolidin-3-yl]butyric acid::2-[(5Z)-5-[(1-methyl-2-pyrrolyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]butanoic acid::2-[(5Z)-5-[(1-methylpyrrol-2-yl)methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid::2-[(5Z)-5-[(1-methylpyrrol-2-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoic acid::2-{5-[1-(1-Methyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-butyric acid::MLS000580912::SMR000220328::cid_5964892 Disintegrin and metalloproteinase domain-containing protein 17 23170 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79676&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5964892 252656322 ZINC02437066 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236280 COc1cc(SC)ccc1C(=O)NCCOc1ccc(C)c(C)c1 InChI=1S/C19H23NO3S/c1-13-5-6-15(11-14(13)2)23-10-9-20-19(21)17-8-7-16(24-4)12-18(17)22-3/h5-8,11-12H,9-10H2,1-4H3,(H,20,21) UEQOJMFNISKIRW-UHFFFAOYSA-N 114033 MLS000583304::N-[2-(3,4-dimethylphenoxy)ethyl]-2-methoxy-4-(methylthio)benzamide::N-[2-(3,4-dimethylphenoxy)ethyl]-2-methoxy-4-methylsulfanyl-benzamide::N-[2-(3,4-dimethylphenoxy)ethyl]-2-methoxy-4-methylsulfanylbenzamide::SMR000201140::cid_614251 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114033&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 614251 252663550 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236281 Cc1ccc(\C=C\C(=O)Nc2ccc(Oc3ccccc3)cc2)o1 InChI=1S/C20H17NO3/c1-15-7-10-18(23-15)13-14-20(22)21-16-8-11-19(12-9-16)24-17-5-3-2-4-6-17/h2-14H,1H3,(H,21,22)/b14-13+ LSNANDNWFJUUDV-BUHFOSPRSA-N 114034 (E)-3-(5-methyl-2-furanyl)-N-(4-phenoxyphenyl)-2-propenamide::(E)-3-(5-methyl-2-furyl)-N-(4-phenoxyphenyl)acrylamide::(E)-3-(5-methylfuran-2-yl)-N-(4-phenoxyphenyl)prop-2-enamide::MLS000578608::SMR000197793::cid_897909 Disintegrin and metalloproteinase domain-containing protein 17 69562 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114034&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 897909 252663551 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236282 COc1ccc(cc1)C(CC(=O)c1ccc(C)cc1)Nc1ccc(cc1)[N+]([O-])=O InChI=1S/C23H22N2O4/c1-16-3-5-18(6-4-16)23(26)15-22(17-7-13-21(29-2)14-8-17)24-19-9-11-20(12-10-19)25(27)28/h3-14,22,24H,15H2,1-2H3 AZIQFIZOMWOWDB-UHFFFAOYSA-N 31354 3-(4-methoxyphenyl)-1-(4-methylphenyl)-3-(4-nitroanilino)-1-propanone::3-(4-methoxyphenyl)-1-(4-methylphenyl)-3-(4-nitroanilino)propan-1-one::3-(4-methoxyphenyl)-1-(4-methylphenyl)-3-[(4-nitrophenyl)amino]-1-propanone::3-(4-methoxyphenyl)-1-(4-methylphenyl)-3-[(4-nitrophenyl)amino]propan-1-one::3-(4-methoxyphenyl)-3-(4-nitroanilino)-1-(p-tolyl)propan-1-one::MLS000583267::SMR000201103::cid_2971621 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31354 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31354&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2971621 252615353 ZINC04757557 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236283 NS(=O)(=O)c1ccc(NCc2cc(Cl)ccc2OCc2ccc(F)cc2)cc1 InChI=1S/C20H18ClFN2O3S/c21-16-3-10-20(27-13-14-1-4-17(22)5-2-14)15(11-16)12-24-18-6-8-19(9-7-18)28(23,25)26/h1-11,24H,12-13H2,(H2,23,25,26) XBTZIZHOWTUCKT-UHFFFAOYSA-N 114035 4-({5-chloro-2-[(4-fluorobenzyl)oxy]benzyl}amino)benzenesulfonamide::4-[[5-chloranyl-2-[(4-fluorophenyl)methoxy]phenyl]methylamino]benzenesulfonamide::4-[[5-chloro-2-(4-fluorobenzyl)oxy-benzyl]amino]benzenesulfonamide::4-[[5-chloro-2-[(4-fluorophenyl)methoxy]phenyl]methylamino]benzenesulfonamide::MLS000583272::SMR000201108::cid_979809 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114035&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 979809 252663552 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236284 CCCn1c(SCC(=O)N2c3ccccc3Sc3ccccc23)nc2ccccc12 InChI=1S/C24H21N3OS2/c1-2-15-26-18-10-4-3-9-17(18)25-24(26)29-16-23(28)27-19-11-5-7-13-21(19)30-22-14-8-6-12-20(22)27/h3-14H,2,15-16H2,1H3 XHCYPJDZLUAMST-UHFFFAOYSA-N 114036 1-(10-phenothiazinyl)-2-[(1-propyl-2-benzimidazolyl)thio]ethanone::1-phenothiazin-10-yl-2-(1-propylbenzimidazol-2-yl)sulfanyl-ethanone::1-phenothiazin-10-yl-2-(1-propylbenzimidazol-2-yl)sulfanylethanone::1-phenothiazin-10-yl-2-[(1-propylbenzimidazol-2-yl)thio]ethanone::10-{[(1-propyl-1H-benzimidazol-2-yl)thio]acetyl}-10H-phenothiazine::MLS000574648::SMR000196076::cid_1333576 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114036&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1333576 252663553 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236285 COc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C(C)(C)C)cc1 InChI=1S/C21H22N2O4/c1-21(2,3)20(25)23-17-15-7-5-6-8-16(15)27-18(17)19(24)22-13-9-11-14(26-4)12-10-13/h5-12H,1-4H3,(H,22,24)(H,23,25) NNZBCPMPXNVQPE-UHFFFAOYSA-N 44653 3-(2,2-dimethylpropanoylamino)-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide::3-[(2,2-dimethyl-1-oxopropyl)amino]-N-(4-methoxyphenyl)-2-benzofurancarboxamide::3-[(2,2-dimethylpropanoyl)amino]-N-(4-methoxyphenyl)-1-benzofuran-2-carboxamide::MLS000092987::N-(4-methoxyphenyl)-3-(pivaloylamino)coumarilamide::SMR000028623::cid_3241060 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44653&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3241060 252625259 ZINC36057480 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236286 O=C(NCC1CCCO1)C(N(Cc1ccccc1)C(=O)c1ccc([nH]1)-c1ccccc1)c1cccs1 InChI=1S/C29H29N3O3S/c33-28(30-19-23-13-7-17-35-23)27(26-14-8-18-36-26)32(20-21-9-3-1-4-10-21)29(34)25-16-15-24(31-25)22-11-5-2-6-12-22/h1-6,8-12,14-16,18,23,27,31H,7,13,17,19-20H2,(H,30,33) JARWWLDFLXGFFO-UHFFFAOYSA-N 113866 5-Phenyl-1H-pyrrole-2-carboxylic acid benzyl-{[(tetrahydro-furan-2-ylmethyl)-carbamoyl]-thiophen-2-yl-methyl}-amide::MLS000564496::N-[2-oxidanylidene-2-(oxolan-2-ylmethylamino)-1-thiophen-2-yl-ethyl]-5-phenyl-N-(phenylmethyl)-1H-pyrrole-2-carboxamide::N-[2-oxo-2-(2-oxolanylmethylamino)-1-thiophen-2-ylethyl]-5-phenyl-N-(phenylmethyl)-1H-pyrrole-2-carboxamide::N-benzyl-N-[2-keto-2-(tetrahydrofurfurylamino)-1-(2-thienyl)ethyl]-5-phenyl-1H-pyrrole-2-carboxamide::N-benzyl-N-[2-oxo-2-(oxolan-2-ylmethylamino)-1-thiophen-2-ylethyl]-5-phenyl-1H-pyrrole-2-carboxamide::SMR000172637::cid_3174569 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113866&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3174569 252663397 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236287 Cc1ccc(o1)C(N(Cc1ccccc1)C(=O)Cc1c[nH]c2ccccc12)C(=O)NC1CCCCC1 InChI=1S/C30H33N3O3/c1-21-16-17-27(36-21)29(30(35)32-24-12-6-3-7-13-24)33(20-22-10-4-2-5-11-22)28(34)18-23-19-31-26-15-9-8-14-25(23)26/h2,4-5,8-11,14-17,19,24,29,31H,3,6-7,12-13,18,20H2,1H3,(H,32,35) RVLNJSBWGUYYJD-UHFFFAOYSA-N 114037 2-[Benzyl-(2-1H-indol-3-yl-acetyl)-amino]-N-cyclohexyl-2-(5-methyl-furan-2-yl)-acetamide::2-[benzyl-[2-(1H-indol-3-yl)acetyl]amino]-N-cyclohexyl-2-(5-methyl-2-furyl)acetamide::2-[benzyl-[2-(1H-indol-3-yl)acetyl]amino]-N-cyclohexyl-2-(5-methylfuran-2-yl)acetamide::MLS000552998::N-cyclohexyl-2-[2-(1H-indol-3-yl)ethanoyl-(phenylmethyl)amino]-2-(5-methylfuran-2-yl)ethanamide::N-cyclohexyl-2-[[2-(1H-indol-3-yl)-1-oxoethyl]-(phenylmethyl)amino]-2-(5-methyl-2-furanyl)acetamide::SMR000172886::cid_3190948 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114037&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3190948 252663554 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236288 Cc1[nH]n(-c2ncc(s2)-c2ccccc2)c(=O)c1C(C(C#N)C#N)c1ccc(Br)cc1 InChI=1S/C23H16BrN5OS/c1-14-20(21(17(11-25)12-26)16-7-9-18(24)10-8-16)22(30)29(28-14)23-27-13-19(31-23)15-5-3-2-4-6-15/h2-10,13,17,21,28H,1H3 QTVFNUICLHWCHG-UHFFFAOYSA-N 50239 2-[(4-bromophenyl)-[5-keto-3-methyl-1-(5-phenylthiazol-2-yl)-3-pyrazolin-4-yl]methyl]malononitrile::2-[(4-bromophenyl)-[5-methyl-3-oxidanylidene-2-(5-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-4-yl]methyl]propanedinitrile::2-[(4-bromophenyl)-[5-methyl-3-oxo-2-(5-phenyl-1,3-thiazol-2-yl)-1H-pyrazol-4-yl]methyl]propanedinitrile::2-[(4-bromophenyl)-[5-methyl-3-oxo-2-(5-phenyl-2-thiazolyl)-1H-pyrazol-4-yl]methyl]propanedinitrile::2-{(4-Bromo-phenyl)-[5-hydroxy-3-methyl-1-(5-phenyl-thiazol-2-yl)-1H-pyrazol-4-yl]-methyl}-malononitrile::MLS000554434::SMR000171677::cid_3117077 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50239 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50239&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3117077 252630505 ZINC04884818 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236289 CCCN1C\C(=C\c2ccc3OCOc3c2)C(=O)\C(C1)=C\c1ccc2OCOc2c1 InChI=1S/C24H23NO5/c1-2-7-25-12-18(8-16-3-5-20-22(10-16)29-14-27-20)24(26)19(13-25)9-17-4-6-21-23(11-17)30-15-28-21/h3-6,8-11H,2,7,12-15H2,1H3/b18-8-,19-9+ BDHNDBUMWWYHMO-NCEWWTOFSA-N 114038 (3Z,5E)-3,5-bis(1,3-benzodioxol-5-ylmethylidene)-1-propyl-4-piperidinone::(3Z,5E)-3,5-bis(1,3-benzodioxol-5-ylmethylidene)-1-propyl-piperidin-4-one::(3Z,5E)-3,5-bis(1,3-benzodioxol-5-ylmethylidene)-1-propylpiperidin-4-one::(3Z,5E)-3,5-dipiperonylidene-1-propyl-4-piperidone::3,5-Bis-benzo[1,3]dioxol-5-ylmethylene-1-propyl-piperidin-4-one::MLS000567516::SMR000175605::cid_1914872 Disintegrin and metalloproteinase domain-containing protein 17 19619 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114038&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1914872 252663555 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236290 COc1cc(NC(=O)CC(C)=NNC(=O)Cc2ccccc2)c(OC)cc1Cl InChI=1S/C20H22ClN3O4/c1-13(23-24-20(26)10-14-7-5-4-6-8-14)9-19(25)22-16-12-17(27-2)15(21)11-18(16)28-3/h4-8,11-12H,9-10H2,1-3H3,(H,22,25)(H,24,26) KXGTVCVXRSPMJH-UHFFFAOYSA-N 114039 (3E)-N-(4-chloranyl-2,5-dimethoxy-phenyl)-3-(2-phenylethanoylhydrazinylidene)butanamide::(3E)-N-(4-chloro-2,5-dimethoxy-phenyl)-3-[(2-phenylacetyl)hydrazono]butyramide::(3E)-N-(4-chloro-2,5-dimethoxyphenyl)-3-[(1-oxo-2-phenylethyl)hydrazinylidene]butanamide::(3E)-N-(4-chloro-2,5-dimethoxyphenyl)-3-[(2-phenylacetyl)hydrazinylidene]butanamide::MLS000567580::N-(4-Chloro-2,5-dimethoxy-phenyl)-3-(phenylacetyl-hydrazono)-butyramide::SMR000174905::cid_9591979 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114039&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9591979 252663556 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236291 CCOc1ccc(CNC(=S)NN=Cc2ccc(OC)c(OC)c2)cc1 InChI=1S/C19H23N3O3S/c1-4-25-16-8-5-14(6-9-16)12-20-19(26)22-21-13-15-7-10-17(23-2)18(11-15)24-3/h5-11,13H,4,12H2,1-3H3,(H2,20,22,26) FCXLTQGDMSICFY-UHFFFAOYSA-N 114040 1-(4-ethoxybenzyl)-3-[(E)-veratrylideneamino]thiourea::1-[(E)-(3,4-dimethoxyphenyl)methylideneamino]-3-[(4-ethoxyphenyl)methyl]thiourea::MLS000567479::SMR000174277::cid_6881975 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114040&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6881975 252663557 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236292 N=C1N2C(SC=C2c2ccccc2)=NC(=O)\C1=C/c1cccn1CCOc1ccccc1 InChI=1S/C25H20N4O2S/c26-23-21(16-19-10-7-13-28(19)14-15-31-20-11-5-2-6-12-20)24(30)27-25-29(23)22(17-32-25)18-8-3-1-4-9-18/h1-13,16-17,26H,14-15H2/b21-16-,26-23? OGOAAPDKPBVTNR-BRDBGPSPSA-N 114041 (6Z)-5-azanylidene-6-[[1-(2-phenoxyethyl)pyrrol-2-yl]methylidene]-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one::(6Z)-5-imino-6-[[1-(2-phenoxyethyl)-2-pyrrolyl]methylidene]-3-phenyl-7-thiazolo[3,2-a]pyrimidinone::(6Z)-5-imino-6-[[1-(2-phenoxyethyl)pyrrol-2-yl]methylene]-3-phenyl-thiazolo[3,2-a]pyrimidin-7-one::(6Z)-5-imino-6-[[1-(2-phenoxyethyl)pyrrol-2-yl]methylidene]-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one::(6Z)-5-imino-6-{[1-(2-phenoxyethyl)-1H-pyrrol-2-yl]methylene}-3-phenyl-5,6-dihydro-7H-[1,3]thiazolo[3,2-a]pyrimidin-7-one::MLS000585324::SMR000204087::cid_6310548 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114041&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6310548 252663558 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236293 COc1ccc(cc1)N1CCC(CNC(=S)Nc2cccc(OC)c2)C1 InChI=1S/C20H25N3O2S/c1-24-18-8-6-17(7-9-18)23-11-10-15(14-23)13-21-20(26)22-16-4-3-5-19(12-16)25-2/h3-9,12,15H,10-11,13-14H2,1-2H3,(H2,21,22,26) YGDGOHBULMCSLI-UHFFFAOYSA-N 50255 1-(3-methoxyphenyl)-3-[[1-(4-methoxyphenyl)-3-pyrrolidinyl]methyl]thiourea::1-(3-methoxyphenyl)-3-[[1-(4-methoxyphenyl)pyrrolidin-3-yl]methyl]thiourea::MLS000584556::N-(3-methoxyphenyl)-N'-{[1-(4-methoxyphenyl)pyrrolidin-3-yl]methyl}thiourea::SMR000207141::cid_3688005 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3688005 252630521 ZINC02310375 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236294 Cc1ccccc1-n1c(SCC(=O)N\N=C\C=C\c2ccccc2[N+]([O-])=O)nc2ccccc2c1=O InChI=1S/C26H21N5O4S/c1-18-9-2-6-14-22(18)30-25(33)20-12-4-5-13-21(20)28-26(30)36-17-24(32)29-27-16-8-11-19-10-3-7-15-23(19)31(34)35/h2-16H,17H2,1H3,(H,29,32)/b11-8+,27-16+ ABUKZRRTEZITBR-JOARMNLUSA-N 114042 (4-Oxo-3-o-tolyl-3,4-dihydro-quinazolin-2-ylsulfanyl)-acetic acid [(E)-3-(2-nitro-phenyl)-prop-2-en-(E)-ylidene]-hydrazide::2-[3-(2-methylphenyl)-4-oxidanylidene-quinazolin-2-yl]sulfanyl-N-[(E)-[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]ethanamide::2-[3-(2-methylphenyl)-4-oxoquinazolin-2-yl]sulfanyl-N-[(E)-[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]acetamide::2-[[3-(2-methylphenyl)-4-oxo-2-quinazolinyl]thio]-N-[(E)-[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]acetamide::2-[[4-keto-3-(o-tolyl)quinazolin-2-yl]thio]-N-[(E)-[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]acetamide::MLS000591112::SMR000217910::cid_1553782 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114042&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1553782 252663559 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236295 CCNC(=S)NN=Cc1cn(Cc2ccccc2F)c2ccccc12 InChI=1S/C19H19FN4S/c1-2-21-19(25)23-22-11-15-13-24(18-10-6-4-8-16(15)18)12-14-7-3-5-9-17(14)20/h3-11,13H,2,12H2,1H3,(H2,21,23,25) SBIFQHONYWCCLQ-UHFFFAOYSA-N 114043 1-ethyl-3-[(E)-[1-(2-fluorobenzyl)indol-3-yl]methyleneamino]thiourea::1-ethyl-3-[(E)-[1-[(2-fluorophenyl)methyl]-3-indolyl]methylideneamino]thiourea::1-ethyl-3-[(E)-[1-[(2-fluorophenyl)methyl]indol-3-yl]methylideneamino]thiourea::MLS000591011::SMR000217737::cid_6863009 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114043&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6863009 252663560 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236296 N=c1c2C(c3ccccc3)c3c(Oc2ncn1Cc1ccco1)ccc1ccccc31 InChI=1S/C26H19N3O2/c27-25-24-22(18-8-2-1-3-9-18)23-20-11-5-4-7-17(20)12-13-21(23)31-26(24)28-16-29(25)15-19-10-6-14-30-19/h1-14,16,22,27H,15H2 YIGBSQVLQFJCDF-UHFFFAOYSA-N 70806 10-Furan-2-ylmethyl-12-phenyl-10,12-dihydro-7-oxa-8,10-diaza-benzo[a]anthracen-11-ylideneamine::MLS000331568::SMR000220659::cid_4691858 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=70806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=70806&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4691858 242053507 ZINC05196295 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236297 Cn1c2cccc3C(=O)c4ccccc4-c(c(Nc4ccc(O)cc4)c1=O)c23 InChI=1S/C23H16N2O3/c1-25-18-8-4-7-17-19(18)20(15-5-2-3-6-16(15)22(17)27)21(23(25)28)24-13-9-11-14(26)12-10-13/h2-12,24,26H,1H3 IBXWGRMKCNKBSN-UHFFFAOYSA-N 51041 MLS000697113::SMR000237907::cid_1263311 Disintegrin and metalloproteinase domain-containing protein 17 69510 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51041&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1263311 242053166 ZINC02503426 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236298 Cc1ccc(cc1)S(=O)(=O)N(CCCO)CC(O)CON=C1c2ccccc2-c2ccccc12 InChI=1S/C26H28N2O5S/c1-19-11-13-21(14-12-19)34(31,32)28(15-6-16-29)17-20(30)18-33-27-26-24-9-4-2-7-22(24)23-8-3-5-10-25(23)26/h2-5,7-14,20,29-30H,6,15-18H2,1H3 YAIYZBXJEQCEIX-UHFFFAOYSA-N 114044 MLS000697256::N-[3-(9-fluorenylideneamino)oxy-2-hydroxypropyl]-N-(3-hydroxypropyl)-4-methylbenzenesulfonamide::N-[3-(fluoren-9-ylideneamino)oxy-2-hydroxy-propyl]-N-(3-hydroxypropyl)-4-methyl-benzenesulfonamide::N-[3-(fluoren-9-ylideneamino)oxy-2-hydroxypropyl]-N-(3-hydroxypropyl)-4-methylbenzenesulfonamide::N-[3-(fluoren-9-ylideneamino)oxy-2-oxidanyl-propyl]-4-methyl-N-(3-oxidanylpropyl)benzenesulfonamide::SMR000237932::cid_12005900 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114044&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12005900 252663561 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236299 Brc1ccc(CN2CCc3c(OCC(=O)N4CCCc5ccccc45)cccc3C2=O)cc1 InChI=1S/C27H25BrN2O3/c28-21-12-10-19(11-13-21)17-29-16-14-22-23(27(29)32)7-3-9-25(22)33-18-26(31)30-15-4-6-20-5-1-2-8-24(20)30/h1-3,5,7-13H,4,6,14-18H2 QKESQDDFGFPGKF-UHFFFAOYSA-N 114045 2-(4-bromobenzyl)-5-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-keto-ethoxy]-3,4-dihydroisocarbostyril::2-[(4-bromophenyl)methyl]-5-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxidanylidene-ethoxy]-3,4-dihydroisoquinolin-1-one::2-[(4-bromophenyl)methyl]-5-[2-(3,4-dihydro-2H-quinolin-1-yl)-2-oxoethoxy]-3,4-dihydroisoquinolin-1-one::MLS000723088::SMR000236096::cid_2151894 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114045&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2151894 252663562 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236300 COc1ccc(cc1)\N=C1/SC(CC(=O)Nc2ccc(F)cc2)C(=O)N1Cc1ccco1 InChI=1S/C23H20FN3O4S/c1-30-18-10-8-17(9-11-18)26-23-27(14-19-3-2-12-31-19)22(29)20(32-23)13-21(28)25-16-6-4-15(24)5-7-16/h2-12,20H,13-14H2,1H3,(H,25,28)/b26-23- MIRSINXPRKRHBF-RWEWTDSWSA-N 114046 MLS000409051::N-(4-fluorophenyl)-2-[3-(2-furanylmethyl)-2-(4-methoxyphenyl)imino-4-oxo-5-thiazolidinyl]acetamide::N-(4-fluorophenyl)-2-[3-(2-furfuryl)-4-keto-2-(4-methoxyphenyl)imino-thiazolidin-5-yl]acetamide::N-(4-fluorophenyl)-2-[3-(furan-2-ylmethyl)-2-(4-methoxyphenyl)imino-4-oxidanylidene-1,3-thiazolidin-5-yl]ethanamide::N-(4-fluorophenyl)-2-[3-(furan-2-ylmethyl)-2-(4-methoxyphenyl)imino-4-oxo-1,3-thiazolidin-5-yl]acetamide::SMR000264011::cid_4345536 Disintegrin and metalloproteinase domain-containing protein 17 69496 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114046&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4345536 252663563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236301 CC(Sc1nc2ccccc2c(=O)n1-c1cc(C)cc(C)c1)C(=O)NCc1ccc2OCOc2c1 InChI=1S/C27H25N3O4S/c1-16-10-17(2)12-20(11-16)30-26(32)21-6-4-5-7-22(21)29-27(30)35-18(3)25(31)28-14-19-8-9-23-24(13-19)34-15-33-23/h4-13,18H,14-15H2,1-3H3,(H,28,31) XZOKREXTDTTYPO-UHFFFAOYSA-N 114047 2-[[3-(3,5-dimethylphenyl)-4-keto-quinazolin-2-yl]thio]-N-piperonyl-propionamide::MLS000334040::N-(1,3-benzodioxol-5-ylmethyl)-2-[3-(3,5-dimethylphenyl)-4-oxidanylidene-quinazolin-2-yl]sulfanyl-propanamide::N-(1,3-benzodioxol-5-ylmethyl)-2-[3-(3,5-dimethylphenyl)-4-oxoquinazolin-2-yl]sulfanylpropanamide::N-(1,3-benzodioxol-5-ylmethyl)-2-[[3-(3,5-dimethylphenyl)-4-oxo-2-quinazolinyl]thio]propanamide::SMR000248798::cid_4023277 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114047&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4023277 252663564 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236302 CCc1ccc(NC(=O)CO\N=C(/C)c2cc3ccccc3o2)cc1 InChI=1S/C20H20N2O3/c1-3-15-8-10-17(11-9-15)21-20(23)13-24-22-14(2)19-12-16-6-4-5-7-18(16)25-19/h4-12H,3,13H2,1-2H3,(H,21,23)/b22-14+ XRTHDIICMYEMID-HYARGMPZSA-N 114048 2-[(E)-1-(1-benzofuran-2-yl)ethylideneamino]oxy-N-(4-ethylphenyl)acetamide::2-[(E)-1-(1-benzofuran-2-yl)ethylideneamino]oxy-N-(4-ethylphenyl)ethanamide::2-[(E)-1-(2-benzofuranyl)ethylideneamino]oxy-N-(4-ethylphenyl)acetamide::2-[(E)-1-(benzofuran-2-yl)ethylideneamino]oxy-N-(4-ethylphenyl)acetamide::MLS000391296::SMR000260333::cid_9568945 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114048&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9568945 252663565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236303 CN(C)S(=O)(=O)c1cc(NC(=O)COC(=O)C(=C\c2cccs2)\c2cccs2)ccc1C InChI=1S/C22H22N2O5S3/c1-15-8-9-16(12-20(15)32(27,28)24(2)3)23-21(25)14-29-22(26)18(19-7-5-11-31-19)13-17-6-4-10-30-17/h4-13H,14H2,1-3H3,(H,23,25)/b18-13+ HMEVYODEGHPDDI-QGOAFFKASA-N 114049 (Z)-2,3-bis(2-thienyl)acrylic acid [2-[3-(dimethylsulfamoyl)-4-methyl-anilino]-2-keto-ethyl] ester::(Z)-2,3-dithiophen-2-yl-2-propenoic acid [2-[3-(dimethylsulfamoyl)-4-methylanilino]-2-oxoethyl] ester::MLS000409385::SMR000247621::[2-[3-(dimethylsulfamoyl)-4-methylanilino]-2-oxoethyl] (Z)-2,3-dithiophen-2-ylprop-2-enoate::[2-[[3-(dimethylsulfamoyl)-4-methyl-phenyl]amino]-2-oxidanylidene-ethyl] (Z)-2,3-dithiophen-2-ylprop-2-enoate::cid_6532763 Disintegrin and metalloproteinase domain-containing protein 17 69487 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114049&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6532763 252663566 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236304 CC(=O)c1cccc(NC(=O)C(OC(=O)c2ccccc2NS(=O)(=O)c2cccs2)c2ccccc2)c1 InChI=1S/C27H22N2O6S2/c1-18(30)20-11-7-12-21(17-20)28-26(31)25(19-9-3-2-4-10-19)35-27(32)22-13-5-6-14-23(22)29-37(33,34)24-15-8-16-36-24/h2-17,25,29H,1H3,(H,28,31) NXMSBWZPDMYQRQ-UHFFFAOYSA-N 113879 2-(2-thienylsulfonylamino)benzoic acid [2-(3-acetylanilino)-2-keto-1-phenyl-ethyl] ester::2-(thiophen-2-ylsulfonylamino)benzoic acid [2-(3-acetylanilino)-2-oxo-1-phenylethyl] ester::MLS000374570::SMR000244185::[2-(3-acetylanilino)-2-oxo-1-phenylethyl] 2-(thiophen-2-ylsulfonylamino)benzoate::[2-[(3-ethanoylphenyl)amino]-2-oxidanylidene-1-phenyl-ethyl] 2-(thiophen-2-ylsulfonylamino)benzoate::cid_3540946 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113879&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3540946 252663410 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236305 COc1ccc(cc1)N(C)S(=O)(=O)c1cccc(c1)C(=O)OC(C(=O)Nc1cc(C)cc(C)c1)c1ccccc1 InChI=1S/C31H30N2O6S/c1-21-17-22(2)19-25(18-21)32-30(34)29(23-9-6-5-7-10-23)39-31(35)24-11-8-12-28(20-24)40(36,37)33(3)26-13-15-27(38-4)16-14-26/h5-20,29H,1-4H3,(H,32,34) FLJQLYIKJDKYRI-UHFFFAOYSA-N 114050 3-[(4-methoxyphenyl)-methyl-sulfamoyl]benzoic acid [2-(3,5-dimethylanilino)-2-keto-1-phenyl-ethyl] ester::3-[(4-methoxyphenyl)-methylsulfamoyl]benzoic acid [2-(3,5-dimethylanilino)-2-oxo-1-phenylethyl] ester::MLS000374657::SMR000244272::[2-(3,5-dimethylanilino)-2-oxo-1-phenylethyl] 3-[(4-methoxyphenyl)-methylsulfamoyl]benzoate::[2-[(3,5-dimethylphenyl)amino]-2-oxidanylidene-1-phenyl-ethyl] 3-[(4-methoxyphenyl)-methyl-sulfamoyl]benzoate::cid_3586637 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114050&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3586637 252663567 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236306 CC(C)C(NS(=O)(=O)c1c(Cl)cccc1Cl)C(=O)OCC(=O)c1c[nH]c2ccccc12 InChI=1S/C21H20Cl2N2O5S/c1-12(2)19(25-31(28,29)20-15(22)7-5-8-16(20)23)21(27)30-11-18(26)14-10-24-17-9-4-3-6-13(14)17/h3-10,12,19,24-25H,11H2,1-2H3 RBYIMXNASLXXRG-UHFFFAOYSA-N 114051 2-[(2,6-dichlorophenyl)sulfonylamino]-3-methyl-butyric acid [2-(1H-indol-3-yl)-2-keto-ethyl] ester::2-[(2,6-dichlorophenyl)sulfonylamino]-3-methylbutanoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester::MLS000409274::SMR000243613::[2-(1H-indol-3-yl)-2-oxidanylidene-ethyl] 2-[[2,6-bis(chloranyl)phenyl]sulfonylamino]-3-methyl-butanoate::[2-(1H-indol-3-yl)-2-oxoethyl] 2-[(2,6-dichlorophenyl)sulfonylamino]-3-methylbutanoate::cid_4834110 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114051&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4834110 252663568 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236307 COc1ccccc1NC(=O)c1c(N)c(sc1Nc1ccccc1C)C(=O)Nc1cccc(Cl)c1 InChI=1S/C26H23ClN4O3S/c1-15-8-3-4-11-18(15)31-26-21(24(32)30-19-12-5-6-13-20(19)34-2)22(28)23(35-26)25(33)29-17-10-7-9-16(27)14-17/h3-14,31H,28H2,1-2H3,(H,29,33)(H,30,32) RGMBRQQTDUXHPX-UHFFFAOYSA-N 68053 3-amino-2-N-(3-chlorophenyl)-4-N-(2-methoxyphenyl)-5-(2-methylanilino)thiophene-2,4-dicarboxamide::3-amino-N-(3-chlorophenyl)-N'-(2-methoxyphenyl)-5-(o-toluidino)thiophene-2,4-dicarboxamide::3-amino-N2-(3-chlorophenyl)-N4-(2-methoxyphenyl)-5-(2-methylanilino)thiophene-2,4-dicarboxamide::3-azanyl-N2-(3-chlorophenyl)-N4-(2-methoxyphenyl)-5-[(2-methylphenyl)amino]thiophene-2,4-dicarboxamide::MLS000394900::SMR000262185::cid_2439674 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68053&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2439674 252646332 ZINC03324194 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236308 CCOc1ccc(\C=C\C(=O)c2cc(Br)ccc(=O)c2O)cc1 InChI=1S/C18H15BrO4/c1-2-23-14-7-3-12(4-8-14)5-9-16(20)15-11-13(19)6-10-17(21)18(15)22/h3-11H,2H2,1H3,(H,21,22)/b9-5+ QHTVWVPIFXIBKA-WEVVVXLNSA-N 55033 5-bromanyl-3-[(E)-3-(4-ethoxyphenyl)prop-2-enoyl]-2-oxidanyl-cyclohepta-2,4,6-trien-1-one::5-bromo-2-hydroxy-3-[(E)-3-p-phenetylacryloyl]cyclohepta-2,4,6-trien-1-one::5-bromo-3-[(E)-3-(4-ethoxyphenyl)-1-oxoprop-2-enyl]-2-hydroxy-1-cyclohepta-2,4,6-trienone::5-bromo-3-[(E)-3-(4-ethoxyphenyl)prop-2-enoyl]-2-hydroxycyclohepta-2,4,6-trien-1-one::5-bromo-3-[3-(4-ethoxyphenyl)acryloyl]-2-hydroxy-2,4,6-cycloheptatrien-1-one::MLS000702106::SMR000229860::cid_7314670 Disintegrin and metalloproteinase domain-containing protein 17 11403 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=55033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=55033&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 7314670 252635041 ZINC04667476 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236309 COCCN=c1scc(-c2cc(OC)ccc2OC)n1N=Cc1c[nH]c2ccccc12 InChI=1S/C23H24N4O3S/c1-28-11-10-24-23-27(26-14-16-13-25-20-7-5-4-6-18(16)20)21(15-31-23)19-12-17(29-2)8-9-22(19)30-3/h4-9,12-15,25H,10-11H2,1-3H3 HJTRYLBBSBWKDJ-UHFFFAOYSA-N 54807 4-(2,5-dimethoxyphenyl)-N-[(Z)-3-indolylidenemethyl]-2-(2-methoxyethylimino)-3-thiazolamine::4-(2,5-dimethoxyphenyl)-N-[(Z)-indol-3-ylidenemethyl]-2-(2-methoxyethylimino)-1,3-thiazol-3-amine::MLS000375345::SMR000254598::[4-(2,5-dimethoxyphenyl)-2-(2-methoxyethylimino)-4-thiazolin-3-yl]-[(Z)-indol-3-ylidenemethyl]amine::cid_6508436 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54807&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6508436 252634824 ZINC00532224 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236310 COCCN=c1scc(-c2cc(OC)c(OC)c(OC)c2)n1N=Cc1c(C)[nH]c2ccccc12 InChI=1S/C25H28N4O4S/c1-16-19(18-8-6-7-9-20(18)28-16)14-27-29-21(15-34-25(29)26-10-11-30-2)17-12-22(31-3)24(33-5)23(13-17)32-4/h6-9,12-15,28H,10-11H2,1-5H3/b26-25-,27-14+ OTVPLLNEWZULNQ-HJQQBXHUSA-N 88885 2-(2-methoxyethylimino)-N-[(Z)-(2-methyl-3-indolylidene)methyl]-4-(3,4,5-trimethoxyphenyl)-3-thiazolamine::2-(2-methoxyethylimino)-N-[(Z)-(2-methylindol-3-ylidene)methyl]-4-(3,4,5-trimethoxyphenyl)-1,3-thiazol-3-amine::MLS000375263::SMR000254516::[2-(2-methoxyethylimino)-4-(3,4,5-trimethoxyphenyl)-4-thiazolin-3-yl]-[(Z)-(2-methylindol-3-ylidene)methyl]amine::cid_6039611 Disintegrin and metalloproteinase domain-containing protein 17 69503 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88885&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6039611 252660501 ZINC38176798 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236311 COc1ccc(OC)c(NC(=O)COC(=O)Cc2ccc(cc2)-c2ccccc2)c1 InChI=1S/C24H23NO5/c1-28-20-12-13-22(29-2)21(15-20)25-23(26)16-30-24(27)14-17-8-10-19(11-9-17)18-6-4-3-5-7-18/h3-13,15H,14,16H2,1-2H3,(H,25,26) NCSJJYDUJBAMSH-UHFFFAOYSA-N 114052 2-(4-phenylphenyl)acetic acid [2-(2,5-dimethoxyanilino)-2-keto-ethyl] ester::2-(4-phenylphenyl)acetic acid [2-(2,5-dimethoxyanilino)-2-oxoethyl] ester::MLS000390725::SMR000259763::[2-(2,5-dimethoxyanilino)-2-oxoethyl] 2-(4-phenylphenyl)acetate::[2-[(2,5-dimethoxyphenyl)amino]-2-oxidanylidene-ethyl] 2-(4-phenylphenyl)ethanoate::cid_2337993 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114052&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2337993 252663569 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236312 Cc1cc(C)n(CCc2nc(cs2)-c2ccc(cc2)C(C)(C)C)n1 InChI=1S/C20H25N3S/c1-14-12-15(2)23(22-14)11-10-19-21-18(13-24-19)16-6-8-17(9-7-16)20(3,4)5/h6-9,12-13H,10-11H2,1-5H3 UEPXYDMWYLQACE-UHFFFAOYSA-N 114053 4-(4-tert-butylphenyl)-2-[2-(3,5-dimethyl-1-pyrazolyl)ethyl]thiazole::4-(4-tert-butylphenyl)-2-[2-(3,5-dimethylpyrazol-1-yl)ethyl]-1,3-thiazole::4-(4-tert-butylphenyl)-2-[2-(3,5-dimethylpyrazol-1-yl)ethyl]thiazole::MLS000392690::SMR000261685::cid_2370269 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114053&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2370269 252663570 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236313 COc1cc(\C=C(/C#N)c2ccccn2)ccc1OCc1ccccc1 InChI=1S/C22H18N2O2/c1-25-22-14-18(13-19(15-23)20-9-5-6-12-24-20)10-11-21(22)26-16-17-7-3-2-4-8-17/h2-14H,16H2,1H3/b19-13+ WGBHBGQVWKLILO-CPNJWEJPSA-N 114054 (Z)-3-(3-methoxy-4-phenylmethoxy-phenyl)-2-pyridin-2-yl-prop-2-enenitrile::(Z)-3-(3-methoxy-4-phenylmethoxyphenyl)-2-(2-pyridinyl)-2-propenenitrile::(Z)-3-(3-methoxy-4-phenylmethoxyphenyl)-2-pyridin-2-ylprop-2-enenitrile::(Z)-3-(4-benzoxy-3-methoxy-phenyl)-2-(2-pyridyl)acrylonitrile::MLS000392553::SMR000261423::cid_6162527 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114054&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6162527 252663571 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236314 Cc1cc(C(=O)OC(C(=O)Nc2ccc(C)cc2)c2ccccc2)c(C)o1 InChI=1S/C22H21NO4/c1-14-9-11-18(12-10-14)23-21(24)20(17-7-5-4-6-8-17)27-22(25)19-13-15(2)26-16(19)3/h4-13,20H,1-3H3,(H,23,24) RSXTUNLPCQGYPR-UHFFFAOYSA-N 114055 2,5-dimethyl-3-furancarboxylic acid [2-(4-methylanilino)-2-oxo-1-phenylethyl] ester::2,5-dimethylfuran-3-carboxylic acid [2-keto-1-phenyl-2-(p-toluidino)ethyl] ester::MLS000394597::SMR000262055::[2-(4-methylanilino)-2-oxo-1-phenylethyl] 2,5-dimethylfuran-3-carboxylate::[2-[(4-methylphenyl)amino]-2-oxidanylidene-1-phenyl-ethyl] 2,5-dimethylfuran-3-carboxylate::cid_4882169 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114055&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4882169 252663572 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236315 Cc1cccc(Nc2nnc(SCC(=O)c3ccc(Br)s3)s2)c1C InChI=1S/C16H14BrN3OS3/c1-9-4-3-5-11(10(9)2)18-15-19-20-16(24-15)22-8-12(21)13-6-7-14(17)23-13/h3-7H,8H2,1-2H3,(H,18,19) SXVGLKQYRROOQE-UHFFFAOYSA-N 44065 1-(5-bromanylthiophen-2-yl)-2-[[5-[(2,3-dimethylphenyl)amino]-1,3,4-thiadiazol-2-yl]sulfanyl]ethanone::1-(5-bromo-2-thienyl)-2-[[5-(2,3-dimethylanilino)-1,3,4-thiadiazol-2-yl]thio]ethanone::1-(5-bromo-2-thiophenyl)-2-[[5-(2,3-dimethylanilino)-1,3,4-thiadiazol-2-yl]thio]ethanone::1-(5-bromothiophen-2-yl)-2-[[5-(2,3-dimethylanilino)-1,3,4-thiadiazol-2-yl]sulfanyl]ethanone::MLS000392234::SMR000261131::cid_2410681 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44065&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2410681 252624692 ZINC03295102 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236316 CCOC(=O)c1c(NC(=O)CSc2nncs2)scc1-c1ccccc1 InChI=1S/C17H15N3O3S3/c1-2-23-16(22)14-12(11-6-4-3-5-7-11)8-24-15(14)19-13(21)9-25-17-20-18-10-26-17/h3-8,10H,2,9H2,1H3,(H,19,21) CJCSLCOSUKQZRQ-UHFFFAOYSA-N 114056 2-[[1-oxo-2-(1,3,4-thiadiazol-2-ylthio)ethyl]amino]-4-phenyl-3-thiophenecarboxylic acid ethyl ester::4-phenyl-2-[[2-(1,3,4-thiadiazol-2-ylthio)acetyl]amino]thiophene-3-carboxylic acid ethyl ester::MLS000388678::SMR000254851::cid_2532272::ethyl 4-phenyl-2-[2-(1,3,4-thiadiazol-2-ylsulfanyl)ethanoylamino]thiophene-3-carboxylate::ethyl 4-phenyl-2-[[2-(1,3,4-thiadiazol-2-ylsulfanyl)acetyl]amino]thiophene-3-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114056&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2532272 252663573 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236317 [O-][N+](=O)c1ccc(Cl)c(c1)S(=O)(=O)N1CCC(CC1)C(=O)Nc1nc2ccc(F)cc2s1 InChI=1S/C19H16ClFN4O5S2/c20-14-3-2-13(25(27)28)10-17(14)32(29,30)24-7-5-11(6-8-24)18(26)23-19-22-15-4-1-12(21)9-16(15)31-19/h1-4,9-11H,5-8H2,(H,22,23,26) HOYKZJHYKWIIDL-UHFFFAOYSA-N 114057 1-(2-chloranyl-5-nitro-phenyl)sulfonyl-N-(6-fluoranyl-1,3-benzothiazol-2-yl)piperidine-4-carboxamide::1-(2-chloro-5-nitro-phenyl)sulfonyl-N-(6-fluoro-1,3-benzothiazol-2-yl)isonipecotamide::1-(2-chloro-5-nitrophenyl)sulfonyl-N-(6-fluoro-1,3-benzothiazol-2-yl)-4-piperidinecarboxamide::1-(2-chloro-5-nitrophenyl)sulfonyl-N-(6-fluoro-1,3-benzothiazol-2-yl)piperidine-4-carboxamide::MLS000393867::SMR000247334::cid_3608891 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114057&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3608891 252663574 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236318 CC(C)N=c1scc(-c2cccs2)n1N=Cc1ccc(O)c(O)c1O InChI=1S/C17H17N3O3S2/c1-10(2)19-17-20(12(9-25-17)14-4-3-7-24-14)18-8-11-5-6-13(21)16(23)15(11)22/h3-10,21-23H,1-2H3 MWXYMRFSDRIXRJ-UHFFFAOYSA-N 34807 (4E)-2,3-bis(oxidanyl)-4-[[(2-propan-2-ylimino-4-thiophen-2-yl-1,3-thiazol-3-yl)amino]methylidene]cyclohexa-2,5-dien-1-one::(4E)-2,3-dihydroxy-4-[[(2-propan-2-ylimino-4-thiophen-2-yl-1,3-thiazol-3-yl)amino]methylidene]cyclohexa-2,5-dien-1-one::(4E)-2,3-dihydroxy-4-[[(2-propan-2-ylimino-4-thiophen-2-yl-3-thiazolyl)amino]methylidene]-1-cyclohexa-2,5-dienone::(4E)-2,3-dihydroxy-4-[[[2-isopropylimino-4-(2-thienyl)-4-thiazolin-3-yl]amino]methylene]cyclohexa-2,5-dien-1-one::MLS000417071::SMR000241936::cid_5882673 Disintegrin and metalloproteinase domain-containing protein 17 31208 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=34807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=34807&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5882673 252617453 ZINC38166355 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236319 COc1ccc(NS(=O)(=O)c2cc(NC(=O)c3cccs3)ccc2N2CCCC2)cc1 InChI=1S/C22H23N3O4S2/c1-29-18-9-6-16(7-10-18)24-31(27,28)21-15-17(23-22(26)20-5-4-14-30-20)8-11-19(21)25-12-2-3-13-25/h4-11,14-15,24H,2-3,12-13H2,1H3,(H,23,26) OTLSGXUBILVHRU-UHFFFAOYSA-N 114058 MLS000401650::N-[3-[(4-methoxyphenyl)sulfamoyl]-4-(1-pyrrolidinyl)phenyl]-2-thiophenecarboxamide::N-[3-[(4-methoxyphenyl)sulfamoyl]-4-pyrrolidin-1-yl-phenyl]thiophene-2-carboxamide::N-[3-[(4-methoxyphenyl)sulfamoyl]-4-pyrrolidin-1-ylphenyl]thiophene-2-carboxamide::N-[3-[(4-methoxyphenyl)sulfamoyl]-4-pyrrolidino-phenyl]thiophene-2-carboxamide::SMR000243483::cid_3381484 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114058&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3381484 252663575 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236320 FC(F)Oc1ccccc1NC(=O)COC(=O)c1cccc(NS(=O)(=O)\C=C\c2ccccc2)c1 InChI=1S/C24H20F2N2O6S/c25-24(26)34-21-12-5-4-11-20(21)27-22(29)16-33-23(30)18-9-6-10-19(15-18)28-35(31,32)14-13-17-7-2-1-3-8-17/h1-15,24,28H,16H2,(H,27,29)/b14-13+ YEOYOORDZHVBMB-BUHFOSPRSA-N 114059 3-[[(E)-2-phenylethenyl]sulfonylamino]benzoic acid [2-[2-(difluoromethoxy)anilino]-2-oxoethyl] ester::3-[[(E)-styryl]sulfonylamino]benzoic acid [2-[2-(difluoromethoxy)anilino]-2-keto-ethyl] ester::MLS000393218::SMR000248048::[2-[2-(difluoromethoxy)anilino]-2-oxoethyl] 3-[[(E)-2-phenylethenyl]sulfonylamino]benzoate::[2-[[2-[bis(fluoranyl)methoxy]phenyl]amino]-2-oxidanylidene-ethyl] 3-[[(E)-2-phenylethenyl]sulfonylamino]benzoate::cid_2484589 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114059 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114059&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2484589 252663576 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236321 Clc1ccccc1-n1c(SCC(=O)Nc2cccc(c2)S(=O)(=O)N2CCOCC2)nc2ccccc2c1=O InChI=1S/C26H23ClN4O5S2/c27-21-9-2-4-11-23(21)31-25(33)20-8-1-3-10-22(20)29-26(31)37-17-24(32)28-18-6-5-7-19(16-18)38(34,35)30-12-14-36-15-13-30/h1-11,16H,12-15,17H2,(H,28,32) DSPMBUUOYNEQSW-UHFFFAOYSA-N 114060 2-[3-(2-chlorophenyl)-4-oxidanylidene-quinazolin-2-yl]sulfanyl-N-(3-morpholin-4-ylsulfonylphenyl)ethanamide::2-[3-(2-chlorophenyl)-4-oxoquinazolin-2-yl]sulfanyl-N-(3-morpholin-4-ylsulfonylphenyl)acetamide::2-[[3-(2-chlorophenyl)-4-keto-quinazolin-2-yl]thio]-N-(3-morpholinosulfonylphenyl)acetamide::2-[[3-(2-chlorophenyl)-4-oxo-2-quinazolinyl]thio]-N-[3-(4-morpholinylsulfonyl)phenyl]acetamide::MLS000393811::SMR000247878::cid_3669223 Disintegrin and metalloproteinase domain-containing protein 17 69488 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114060 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114060&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3669223 252663577 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236322 FC(F)Oc1ccc(\C=C\C(=O)OCC(=O)Nc2ccc(cc2)S(=O)(=O)N2CCCC2)cc1 InChI=1S/C22H22F2N2O6S/c23-22(24)32-18-8-3-16(4-9-18)5-12-21(28)31-15-20(27)25-17-6-10-19(11-7-17)33(29,30)26-13-1-2-14-26/h3-12,22H,1-2,13-15H2,(H,25,27)/b12-5+ RRZPCTIHSRFTFH-LFYBBSHMSA-N 114061 (E)-3-[4-(difluoromethoxy)phenyl]-2-propenoic acid [2-oxo-2-[4-(1-pyrrolidinylsulfonyl)anilino]ethyl] ester::(E)-3-[4-(difluoromethoxy)phenyl]acrylic acid [2-keto-2-(4-pyrrolidinosulfonylanilino)ethyl] ester::MLS000374612::SMR000244227::[2-oxidanylidene-2-[(4-pyrrolidin-1-ylsulfonylphenyl)amino]ethyl] (E)-3-[4-[bis(fluoranyl)methoxy]phenyl]prop-2-enoate::[2-oxo-2-(4-pyrrolidin-1-ylsulfonylanilino)ethyl] (E)-3-[4-(difluoromethoxy)phenyl]prop-2-enoate::cid_5951727 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114061 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114061&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5951727 252663578 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236323 CN(c1ccccc1)S(=O)(=O)c1ccc(cc1)C(=O)Nc1ccc2nc(C)sc2c1 InChI=1S/C22H19N3O3S2/c1-15-23-20-13-10-17(14-21(20)29-15)24-22(26)16-8-11-19(12-9-16)30(27,28)25(2)18-6-4-3-5-7-18/h3-14H,1-2H3,(H,24,26) JTQPNHLBFHFLIB-UHFFFAOYSA-N 114062 MLS000394799::N-(2-methyl-1,3-benzothiazol-6-yl)-4-[methyl(phenyl)sulfamoyl]benzamide::SMR000242960::cid_2094919 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114062 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114062&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2094919 252663579 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236324 CN(C)S(=O)(=O)c1cccc(NC(=O)COC(=O)c2cccc(c2)S(=O)(=O)N2CCc3ccccc3C2)c1 InChI=1S/C26H27N3O7S2/c1-28(2)37(32,33)24-12-6-10-22(16-24)27-25(30)18-36-26(31)20-9-5-11-23(15-20)38(34,35)29-14-13-19-7-3-4-8-21(19)17-29/h3-12,15-16H,13-14,17-18H2,1-2H3,(H,27,30) DDKFAVKGMBDLLF-UHFFFAOYSA-N 114063 3-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)benzoic acid [2-[3-(dimethylsulfamoyl)anilino]-2-keto-ethyl] ester::3-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)benzoic acid [2-[3-(dimethylsulfamoyl)anilino]-2-oxoethyl] ester::MLS000402272::SMR000242988::[2-[3-(dimethylsulfamoyl)anilino]-2-oxoethyl] 3-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)benzoate::[2-[[3-(dimethylsulfamoyl)phenyl]amino]-2-oxidanylidene-ethyl] 3-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)benzoate::cid_5018698 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114063 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114063&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5018698 252663580 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236325 CC(OC(=O)CCCCCN=C1NS(=O)(=O)c2ccccc12)C(=O)Nc1cc(Cl)cc(Cl)c1 InChI=1S/C22H23Cl2N3O5S/c1-14(22(29)26-17-12-15(23)11-16(24)13-17)32-20(28)9-3-2-6-10-25-21-18-7-4-5-8-19(18)33(30,31)27-21/h4-5,7-8,11-14H,2-3,6,9-10H2,1H3,(H,25,27)(H,26,29) MYHCCODYUZNMMB-UHFFFAOYSA-N 114064 6-[(1,1-diketo-1,2-benzothiazol-3-yl)amino]hexanoic acid [2-(3,5-dichloroanilino)-2-keto-1-methyl-ethyl] ester::6-[(1,1-dioxo-1,2-benzothiazol-3-yl)amino]hexanoic acid [1-(3,5-dichloroanilino)-1-oxopropan-2-yl] ester::MLS000402324::SMR000243013::[1-(3,5-dichloroanilino)-1-oxopropan-2-yl] 6-[(1,1-dioxo-1,2-benzothiazol-3-yl)amino]hexanoate::[1-[[3,5-bis(chloranyl)phenyl]amino]-1-oxidanylidene-propan-2-yl] 6-[[1,1-bis(oxidanylidene)-1,2-benzothiazol-3-yl]amino]hexanoate::cid_3312168 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114064 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114064&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3312168 252663581 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236326 CN(C)S(=O)(=O)c1cccc(NC(=O)c2cc(nn2-c2cccc(Cl)c2)-c2cccs2)c1 InChI=1S/C22H19ClN4O3S2/c1-26(2)32(29,30)18-9-4-7-16(13-18)24-22(28)20-14-19(21-10-5-11-31-21)25-27(20)17-8-3-6-15(23)12-17/h3-14H,1-2H3,(H,24,28) VGMIGXCDNGIWSA-UHFFFAOYSA-N 114065 2-(3-chlorophenyl)-N-[3-(dimethylsulfamoyl)phenyl]-5-(2-thienyl)pyrazole-3-carboxamide::2-(3-chlorophenyl)-N-[3-(dimethylsulfamoyl)phenyl]-5-thiophen-2-yl-3-pyrazolecarboxamide::2-(3-chlorophenyl)-N-[3-(dimethylsulfamoyl)phenyl]-5-thiophen-2-yl-pyrazole-3-carboxamide::2-(3-chlorophenyl)-N-[3-(dimethylsulfamoyl)phenyl]-5-thiophen-2-ylpyrazole-3-carboxamide::MLS000402283::SMR000242999::cid_4333298 Disintegrin and metalloproteinase domain-containing protein 17 69489 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114065 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114065&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4333298 252663582 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236327 COc1ccc(NS(=O)(=O)c2ccc(OC)c(NC(=O)CCC3CCCC3)c2)cc1 InChI=1S/C22H28N2O5S/c1-28-18-10-8-17(9-11-18)24-30(26,27)19-12-13-21(29-2)20(15-19)23-22(25)14-7-16-5-3-4-6-16/h8-13,15-16,24H,3-7,14H2,1-2H3,(H,23,25) RNBJHTQJMIMQOJ-UHFFFAOYSA-N 114066 3-cyclopentyl-N-[2-methoxy-5-[(4-methoxyphenyl)sulfamoyl]phenyl]propanamide::3-cyclopentyl-N-[2-methoxy-5-[(4-methoxyphenyl)sulfamoyl]phenyl]propionamide::MLS000339467::SMR000244082::cid_4196399 Disintegrin and metalloproteinase domain-containing protein 17 69497 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114066 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114066&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4196399 252663583 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236328 COc1cc(C=NNC(=O)c2cc(nc3ccccc23)-c2ccccc2OC(C)C)ccc1O InChI=1S/C27H25N3O4/c1-17(2)34-25-11-7-5-9-20(25)23-15-21(19-8-4-6-10-22(19)29-23)27(32)30-28-16-18-12-13-24(31)26(14-18)33-3/h4-17,31H,1-3H3,(H,30,32) FHMBUCAZNBSCNG-UHFFFAOYSA-N 114067 2-(2-isopropoxyphenyl)-N'-[(E)-(4-keto-3-methoxy-cyclohexa-2,5-dien-1-ylidene)methyl]cinchoninohydrazide::MLS000705003::N'-(4-hydroxy-3-methoxybenzylidene)-2-(2-isopropoxyphenyl)-4-quinolinecarbohydrazide::N'-[(E)-(3-methoxy-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]-2-(2-propan-2-yloxyphenyl)quinoline-4-carbohydrazide::N'-[(E)-(3-methoxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-2-(2-propan-2-yloxyphenyl)-4-quinolinecarbohydrazide::N'-[(E)-(3-methoxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2-(2-propan-2-yloxyphenyl)quinoline-4-carbohydrazide::SMR000231219::cid_6040123 Disintegrin and metalloproteinase domain-containing protein 17 69494 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114067&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6040123 252663584 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236329 CC1CCc2c(C1)scc2-c1n[nH]c(=S)n1CC=C InChI=1S/C14H17N3S2/c1-3-6-17-13(15-16-14(17)18)11-8-19-12-7-9(2)4-5-10(11)12/h3,8-9H,1,4-7H2,2H3,(H,16,18) AMDCSXGQMORJKP-UHFFFAOYSA-N 114068 3-(6-methyl-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)-4-prop-2-enyl-1H-1,2,4-triazole-5-thione::4-allyl-3-(6-methyl-4,5,6,7-tetrahydrobenzothiophen-3-yl)-1H-1,2,4-triazole-5-thione::4-allyl-5-(6-methyl-4,5,6,7-tetrahydro-1-benzothien-3-yl)-4H-1,2,4-triazol-3-yl hydrosulfide::MLS000700437::SMR000228157::cid_3422428 Disintegrin and metalloproteinase domain-containing protein 17 69449 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114068&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3422428 252663585 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236330 CCOc1cccc(OCCOc2ccc(cc2)C(=O)c2ccccc2)c1 InChI=1S/C23H22O4/c1-2-25-21-9-6-10-22(17-21)27-16-15-26-20-13-11-19(12-14-20)23(24)18-7-4-3-5-8-18/h3-14,17H,2,15-16H2,1H3 FBHIVHNFNSLKBD-UHFFFAOYSA-N 114069 MLS000681540::SMR000269209::[4-[2-(3-ethoxyphenoxy)ethoxy]phenyl]-phenyl-methanone::[4-[2-(3-ethoxyphenoxy)ethoxy]phenyl]-phenylmethanone::cid_2283081::{4-[2-(3-ethoxyphenoxy)ethoxy]phenyl}(phenyl)methanone Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114069&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2283081 252663586 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236331 CC(C)(C)c1ccc(cc1)-c1nc(NCc2cccnc2)c2ccccc2n1 InChI=1S/C24H24N4/c1-24(2,3)19-12-10-18(11-13-19)22-27-21-9-5-4-8-20(21)23(28-22)26-16-17-7-6-14-25-15-17/h4-15H,16H2,1-3H3,(H,26,27,28) RMAUGEQBABUQJD-UHFFFAOYSA-N 114070 2-(4-tert-butylphenyl)-N-(3-pyridinylmethyl)-4-quinazolinamine::2-(4-tert-butylphenyl)-N-(pyridin-3-ylmethyl)quinazolin-4-amine::MLS000681488::SMR000269163::[2-(4-tert-butylphenyl)quinazolin-4-yl]-(3-pyridylmethyl)amine::cid_1185486 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114070&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1185486 252663587 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236332 O=C(C[n+]1ccccc1)Nc1nc2ccccc2s1 InChI=1S/C14H11N3OS/c18-13(10-17-8-4-1-5-9-17)16-14-15-11-6-2-3-7-12(11)19-14/h1-9H,10H2/p+1 VLGMJRFLQJGUAA-UHFFFAOYSA-O 114071 1-[2-(1,3-benzothiazol-2-ylamino)-2-oxoethyl]pyridinium chloride::MLS000686510::N-(1,3-benzothiazol-2-yl)-2-(1-pyridin-1-iumyl)acetamide;chloride::N-(1,3-benzothiazol-2-yl)-2-pyridin-1-ium-1-yl-acetamide;chloride::N-(1,3-benzothiazol-2-yl)-2-pyridin-1-ium-1-yl-ethanamide;chloride::N-(1,3-benzothiazol-2-yl)-2-pyridin-1-ium-1-ylacetamide;chloride::SMR000268160::cid_2884818 Disintegrin and metalloproteinase domain-containing protein 17 69510 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114071&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2267381 252663588 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236333 CCOc1ccc(NC(=O)Cc2sc(=O)n(c2O)-c2ccccc2)cc1 InChI=1S/C19H18N2O4S/c1-2-25-15-10-8-13(9-11-15)20-17(22)12-16-18(23)21(19(24)26-16)14-6-4-3-5-7-14/h3-11,23H,2,12H2,1H3,(H,20,22) RFJNAABEPISPES-UHFFFAOYSA-N 114072 2-(2,4-diketo-3-phenyl-thiazolidin-5-yl)-N-p-phenetyl-acetamide::2-(2,4-dioxo-3-phenyl-1,3-thiazolidin-5-yl)-N-(4-ethoxyphenyl)acetamide::2-(2,4-dioxo-3-phenyl-5-thiazolidinyl)-N-(4-ethoxyphenyl)acetamide::2-[2,4-bis(oxidanylidene)-3-phenyl-1,3-thiazolidin-5-yl]-N-(4-ethoxyphenyl)ethanamide::MLS000717650::SMR000287423::cid_3153587 Disintegrin and metalloproteinase domain-containing protein 17 5733 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114072 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114072&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899706 252663589 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236334 COc1cc(OC)cc(c1)-c1cn[nH]c1N InChI=1S/C11H13N3O2/c1-15-8-3-7(4-9(5-8)16-2)10-6-13-14-11(10)12/h3-6H,1-2H3,(H3,12,13,14) VWVFWTIOFGDRSR-UHFFFAOYSA-N 114073 4-(3,5-dimethoxyphenyl)-1H-pyrazol-5-amine::MLS000675581::SMR000293990::[4-(3,5-dimethoxyphenyl)-1H-pyrazol-5-yl]amine::cid_978094 Disintegrin and metalloproteinase domain-containing protein 17 69468 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114073&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 978094 252663590 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236335 Cc1ccc(NC2=C(OC(=O)c3ccc(C)cc3)OC(=O)C2Cl)cc1 InChI=1S/C19H16ClNO4/c1-11-3-7-13(8-4-11)17(22)24-19-16(15(20)18(23)25-19)21-14-9-5-12(2)6-10-14/h3-10,15,21H,1-2H3 FXKXCZLPTOWIRZ-UHFFFAOYSA-N 114074 4-chloro-3-[(4-methylphenyl)amino]-5-oxo-2,5-dihydrofuran-2-yl 4-methylbenzoate::4-methylbenzoic acid [4-chloro-3-(4-methylanilino)-5-oxo-2H-furan-2-yl] ester::4-methylbenzoic acid [4-chloro-5-keto-3-(p-toluidino)-2H-furan-2-yl] ester::MLS000724381::SMR000305975::[4-chloranyl-3-[(4-methylphenyl)amino]-5-oxidanylidene-2H-furan-2-yl] 4-methylbenzoate::[4-chloro-3-(4-methylanilino)-5-oxo-2H-furan-2-yl] 4-methylbenzoate::cid_16188062 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114074 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114074&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91472271 252663591 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236336 COc1ccccc1\C=C\C1N2C(=O)CCSC2=NC(C)=C1C(=O)OCC(C)C InChI=1S/C22H26N2O4S/c1-14(2)13-28-21(26)20-15(3)23-22-24(19(25)11-12-29-22)17(20)10-9-16-7-5-6-8-18(16)27-4/h5-10,14,17H,11-13H2,1-4H3/b10-9+ ASGZOHIKTAMBGT-MDZDMXLPSA-N 114075 2-methylpropyl 6-[(E)-2-(2-methoxyphenyl)ethenyl]-8-methyl-4-oxidanylidene-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate::2-methylpropyl 6-[(E)-2-(2-methoxyphenyl)ethenyl]-8-methyl-4-oxo-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate::4-keto-6-[(E)-2-(2-methoxyphenyl)vinyl]-8-methyl-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid isobutyl ester::6-[(E)-2-(2-methoxyphenyl)ethenyl]-8-methyl-4-oxo-3,6-dihydro-2H-pyrimido[2,1-b][1,3]thiazine-7-carboxylic acid 2-methylpropyl ester::MLS000727543::SMR000306240::cid_5322450::isobutyl 6-[(E)-2-(2-methoxyphenyl)vinyl]-8-methyl-4-oxo-3,4-dihydro-2H,6H-pyrimido[2,1-b][1,3]thiazine-7-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114075&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5322450 252663592 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236337 CCN(c1ccccc1)S(=O)(=O)c1cc(ccc1C)C(=O)OC(C)C(=O)Nc1ccc2OCCOc2c1 InChI=1S/C27H28N2O7S/c1-4-29(22-8-6-5-7-9-22)37(32,33)25-16-20(11-10-18(25)2)27(31)36-19(3)26(30)28-21-12-13-23-24(17-21)35-15-14-34-23/h5-13,16-17,19H,4,14-15H2,1-3H3,(H,28,30) QZXPNTYGSCOCNN-UHFFFAOYSA-N 82783 3-[ethyl(phenyl)sulfamoyl]-4-methyl-benzoic acid [2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-keto-1-methyl-ethyl] ester::3-[ethyl(phenyl)sulfamoyl]-4-methylbenzoic acid [1-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-1-oxopropan-2-yl] ester::MLS000394788::SMR000242949::[1-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-1-oxidanylidene-propan-2-yl] 3-[ethyl(phenyl)sulfamoyl]-4-methyl-benzoate::[1-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-1-oxopropan-2-yl] 3-[ethyl(phenyl)sulfamoyl]-4-methylbenzoate::cid_5204584 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=82783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=82783&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5204584 252657987 ZINC03306380 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236338 CC(OC(=O)c1cc(=O)[nH]c2ccc(cc12)S(=O)(=O)Nc1cccc(C)c1)C(=O)Nc1ccc(cc1)[N+]([O-])=O InChI=1S/C26H22N4O8S/c1-15-4-3-5-18(12-15)29-39(36,37)20-10-11-23-21(13-20)22(14-24(31)28-23)26(33)38-16(2)25(32)27-17-6-8-19(9-7-17)30(34)35/h3-14,16,29H,1-2H3,(H,27,32)(H,28,31) NAFFXJIRYIJLSO-UHFFFAOYSA-N 114076 2-keto-6-(m-tolylsulfamoyl)-1H-quinoline-4-carboxylic acid [2-keto-1-methyl-2-(4-nitroanilino)ethyl] ester::6-[(3-methylphenyl)sulfamoyl]-2-oxo-1H-quinoline-4-carboxylic acid [1-(4-nitroanilino)-1-oxopropan-2-yl] ester::MLS000409363::SMR000247599::[1-(4-nitroanilino)-1-oxopropan-2-yl] 6-[(3-methylphenyl)sulfamoyl]-2-oxo-1H-quinoline-4-carboxylate::[1-[(4-nitrophenyl)amino]-1-oxidanylidene-propan-2-yl] 6-[(3-methylphenyl)sulfamoyl]-2-oxidanylidene-1H-quinoline-4-carboxylate::cid_4831299 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114076&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4831299 252663593 C02125 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236339 COc1cccc(CNc2ccc(cc2C)[N+]([O-])=O)c1 InChI=1S/C15H16N2O3/c1-11-8-13(17(18)19)6-7-15(11)16-10-12-4-3-5-14(9-12)20-2/h3-9,16H,10H2,1-2H3 PUGDKZBPMHPDOZ-UHFFFAOYSA-N 90473 MLS000687443::N-[(3-methoxyphenyl)methyl]-2-methyl-4-nitro-aniline::N-[(3-methoxyphenyl)methyl]-2-methyl-4-nitroaniline::SMR000283460::cid_2850298::m-anisyl-(2-methyl-4-nitro-phenyl)amine Disintegrin and metalloproteinase domain-containing protein 17 69480 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=90473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=90473&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2850298 252662031 ZINC04309322 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236340 C[C-](\N=[NH+]\c1ccc(cc1)[N+]([O-])=O)c1ccc(C)cc1C InChI=1S/C16H16N3O2/c1-11-4-9-16(12(2)10-11)13(3)17-18-14-5-7-15(8-6-14)19(20)21/h4-10H,1-3H3/q-1/p+1/b18-17+ UDVWYDGJTHPKNH-ISLYRVAYSA-O 114077 (1Z)-1-(2,4-dimethylphenyl)ethanone (4-nitrophenyl)hydrazone::MLS000720085::N-[(Z)-1-(2,4-dimethylphenyl)ethylideneamino]-4-nitro-aniline::N-[(Z)-1-(2,4-dimethylphenyl)ethylideneamino]-4-nitroaniline::SMR000304614::[(Z)-1-(2,4-dimethylphenyl)ethylideneamino]-(4-nitrophenyl)amine::cid_5866130 Disintegrin and metalloproteinase domain-containing protein 17 69454 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114077&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5866130 252663594 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236341 Clc1ccc(COc2ccsc2-c2n[nH]c(=S)[nH]2)c(Cl)c1 InChI=1S/C13H7Cl2N3OS2/c14-8-2-1-7(9(15)5-8)6-19-10-3-4-21-11(10)12-16-13(20)18-17-12/h1-5H,6H2 FOVZULRIUUWNFJ-UHFFFAOYSA-N 88044 5-[3-(2,4-dichlorobenzyl)oxy-2-thienyl]-1,2-dihydro-1,2,4-triazole-3-thione::5-[3-[(2,4-dichlorophenyl)methoxy]-2-thiophenyl]-1,2-dihydro-1,2,4-triazole-3-thione::5-[3-[(2,4-dichlorophenyl)methoxy]thiophen-2-yl]-1,2-dihydro-1,2,4-triazole-3-thione::5-{3-[(2,4-dichlorobenzyl)oxy]-2-thienyl}-4H-1,2,4-triazole-3-thiol::MLS000692154::SMR000333834::cid_1482551 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88044&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1482551 252660104 ZINC13545048 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236342 CN(C)Cc1c(O)cc(=C)c2c(O)c(=Cc3ccco3)oc12 InChI=1S/C17H17NO4/c1-10-7-13(19)12(9-18(2)3)17-15(10)16(20)14(22-17)8-11-5-4-6-21-11/h4-8,19-20H,1,9H2,2-3H3 SETGXSFSGNEYSN-UHFFFAOYSA-N 53106 (2Z)-7-[(dimethylamino)methyl]-2-(2-furanylmethylidene)-6-hydroxy-4-methyl-3-benzofuranone::(2Z)-7-[(dimethylamino)methyl]-2-(2-furfurylidene)-6-hydroxy-4-methyl-coumaran-3-one::(2Z)-7-[(dimethylamino)methyl]-2-(furan-2-ylmethylidene)-4-methyl-6-oxidanyl-1-benzofuran-3-one::(2Z)-7-[(dimethylamino)methyl]-2-(furan-2-ylmethylidene)-6-hydroxy-4-methyl-1-benzofuran-3-one::MLS001215904::SMR000544767::cid_8057369 Disintegrin and metalloproteinase domain-containing protein 17 17004 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53106&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91897102 252633239 ZINC04139974 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236343 Nc1cc(ccc1Oc1ccc(Cl)cc1)S(=O)(=O)N1CCCCC1 InChI=1S/C17H19ClN2O3S/c18-13-4-6-14(7-5-13)23-17-9-8-15(12-16(17)19)24(21,22)20-10-2-1-3-11-20/h4-9,12H,1-3,10-11,19H2 QKFYVRLUWICUGC-UHFFFAOYSA-N 114078 2-(4-chloranylphenoxy)-5-piperidin-1-ylsulfonyl-aniline::2-(4-chlorophenoxy)-5-(1-piperidinylsulfonyl)aniline::2-(4-chlorophenoxy)-5-piperidin-1-ylsulfonylaniline::MLS001002130::SMR000368250::[2-(4-chlorophenoxy)-5-piperidinosulfonyl-phenyl]amine::cid_3487927 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114078&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3487927 252663595 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236344 Fc1ccc(cc1)C(CNC(=O)c1ccc(Br)o1)N1CCOCC1 InChI=1S/C17H18BrFN2O3/c18-16-6-5-15(24-16)17(22)20-11-14(21-7-9-23-10-8-21)12-1-3-13(19)4-2-12/h1-6,14H,7-11H2,(H,20,22) TUKUCXHWROPNBD-UHFFFAOYSA-N 114079 5-bromanyl-N-[2-(4-fluorophenyl)-2-morpholin-4-yl-ethyl]furan-2-carboxamide;hydrochloride::5-bromo-N-[2-(4-fluorophenyl)-2-(4-morpholinyl)ethyl]-2-furancarboxamide;hydrochloride::5-bromo-N-[2-(4-fluorophenyl)-2-morpholin-4-ylethyl]furan-2-carboxamide;hydrochloride::5-bromo-N-[2-(4-fluorophenyl)-2-morpholino-ethyl]-2-furamide;hydrochloride::MLS000879922::SMR000065696::cid_6603386 Disintegrin and metalloproteinase domain-containing protein 17 69496 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114079&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2999333 252663596 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236345 CC(=O)n1cc([C@H]2C[C@@H](OCc3ccc(CO)cc3)OC(=C2)C(=O)Nc2ccccc2)c2ccccc12 InChI=1S/C30H28N2O5/c1-20(34)32-17-26(25-9-5-6-10-27(25)32)23-15-28(30(35)31-24-7-3-2-4-8-24)37-29(16-23)36-19-22-13-11-21(18-33)12-14-22/h2-15,17,23,29,33H,16,18-19H2,1H3,(H,31,35)/t23-,29+/m1/s1 GBDNDLPRUVYQTN-BTYSJIOQSA-N 114080 (2S,4S)-4-(1-acetyl-3-indolyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::(2S,4S)-4-(1-acetylindol-3-yl)-2-(4-methylolbenzyl)oxy-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::(2S,4S)-4-(1-acetylindol-3-yl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::(2S,4S)-4-(1-ethanoylindol-3-yl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::MLS000766544::SMR000441989::cid_16197075 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114080&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16197075 252663597 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236346 OCc1ccc(CO[C@@H]2C[C@@H](C=C(O2)C(=O)Nc2ccccc2)C2CCCCC2)cc1 InChI=1S/C26H31NO4/c28-17-19-11-13-20(14-12-19)18-30-25-16-22(21-7-3-1-4-8-21)15-24(31-25)26(29)27-23-9-5-2-6-10-23/h2,5-6,9-15,21-22,25,28H,1,3-4,7-8,16-18H2,(H,27,29)/t22-,25+/m1/s1 MPSIHTHUEGTEIM-RDGATRHJSA-N 114081 (2S,4R)-4-cyclohexyl-2-(4-methylolbenzyl)oxy-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::(2S,4R)-4-cyclohexyl-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::MLS000766554::SMR000441980::cid_16197078 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114081&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16197078 252663598 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236347 CCO[C@H]1OC(=C[C@H]([C@@H]1CCCO)c1csc2ccccc12)C(=O)Nc1ccccc1 InChI=1S/C25H27NO4S/c1-2-29-25-19(12-8-14-27)20(21-16-31-23-13-7-6-11-18(21)23)15-22(30-25)24(28)26-17-9-4-3-5-10-17/h3-7,9-11,13,15-16,19-20,25,27H,2,8,12,14H2,1H3,(H,26,28)/t19-,20+,25-/m0/s1 DPIFUIZFNOZKRB-DFIYOIEZSA-N 114082 (2S,3S,4R)-4-(1-benzothiophen-3-yl)-2-ethoxy-3-(3-hydroxypropyl)-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::(2S,3S,4R)-4-(1-benzothiophen-3-yl)-2-ethoxy-3-(3-oxidanylpropyl)-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::(2S,3S,4R)-4-(benzothiophen-3-yl)-2-ethoxy-3-(3-hydroxypropyl)-N-phenyl-3,4-dihydro-2H-pyran-6-carboxamide::MLS000766570::SMR000441998::cid_16197121 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114082&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16197121 252663599 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236348 Cc1cccc(NNC2=c3cc(Br)ccc3=NC2=O)c1 InChI=1S/C15H12BrN3O/c1-9-3-2-4-11(7-9)18-19-14-12-8-10(16)5-6-13(12)17-15(14)20/h2-8,18H,1H3,(H,17,19,20) GUZUNQDNJPXMGG-UHFFFAOYSA-N 53163 (3E)-5-bromo-1H-indole-2,3-dione 3-[(3-methylphenyl)hydrazone]::5-bromanyl-3-[2-(3-methylphenyl)hydrazinyl]indol-2-one::5-bromo-3-[(3-methylphenyl)hydrazo]-2-indolone::5-bromo-3-[2-(3-methylphenyl)hydrazinyl]indol-2-one::5-bromo-3-[N'-(m-tolyl)hydrazino]indol-2-one::MLS001201321::SMR000564051::cid_5967902 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53163&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5967902 252633295 ZINC05532912 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236349 Cc1ccccc1NC1=NC(=O)C(S1)=Cc1cccn1C InChI=1S/C16H15N3OS/c1-11-6-3-4-8-13(11)17-16-18-15(20)14(21-16)10-12-7-5-9-19(12)2/h3-10H,1-2H3,(H,17,18,20) MXOCRJFHQPCTNY-UHFFFAOYSA-N 114083 (5Z)-2-(2-methylanilino)-5-[(1-methyl-2-pyrrolyl)methylidene]-4-thiazolone::(5Z)-2-(2-methylanilino)-5-[(1-methylpyrrol-2-yl)methylidene]-1,3-thiazol-4-one::(5Z)-2-[(2-methylphenyl)amino]-5-[(1-methylpyrrol-2-yl)methylidene]-1,3-thiazol-4-one::(5Z)-5-[(1-methylpyrrol-2-yl)methylene]-2-(o-toluidino)-2-thiazolin-4-one::5-[1-(1-Methyl-1H-pyrrol-2-yl)-meth-(Z)-ylidene]-2-o-tolylamino-thiazol-4-one::MLS000333675::SMR000437831::cid_6974998 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114083&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6974998 252663600 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236350 OC(CS)C(O)CSC(=O)c1cccs1 InChI=1S/C9H12O3S3/c10-6(4-13)7(11)5-15-9(12)8-2-1-3-14-8/h1-3,6-7,10-11,13H,4-5H2 QRUCCBJNKMZJKZ-UHFFFAOYSA-N 37867 2-thiophenecarbothioic acid S-(2,3-dihydroxy-4-mercaptobutyl) ester::PC-0095745::PCMD-CC-MCM-30::S-(2,3-dihydroxy-4-sulfanylbutyl) thiophene-2-carbothioate::S-[2,3-bis(oxidanyl)-4-sulfanyl-butyl] thiophene-2-carbothioate::cid_11834395::thiophene-2-carbothioic acid S-(2,3-dihydroxy-4-mercapto-butyl) ester Disintegrin and metalloproteinase domain-containing protein 17 3763 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=37867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=37867&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11834395 252618826 ZINC13687432 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236351 C[C@H](NC(=O)c1nc[nH]c1C(=O)NC(c1ccccc1)c1ccccc1)C(=O)OCc1ccccc1 InChI=1S/C28H26N4O4/c1-19(28(35)36-17-20-11-5-2-6-12-20)31-26(33)24-25(30-18-29-24)27(34)32-23(21-13-7-3-8-14-21)22-15-9-4-10-16-22/h2-16,18-19,23H,17H2,1H3,(H,29,30)(H,31,33)(H,32,34)/t19-/m0/s1 HPVJLRBJHFUZCV-IBGZPJMESA-N 114084 (2S)-2-[[5-(benzhydrylcarbamoyl)-1H-imidazole-4-carbonyl]amino]propionic acid benzyl ester::(2S)-2-[[[5-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]propanoic acid (phenylmethyl) ester::(phenylmethyl) (2S)-2-[[5-[(diphenylmethyl)carbamoyl]-1H-imidazol-4-yl]carbonylamino]propanoate::ILP-II-45::MLS000834711::SMR000394119::benzyl (2S)-2-[[5-(benzhydrylcarbamoyl)-1H-imidazole-4-carbonyl]amino]propanoate::cid_16745356 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114084&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16745356 252663601 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236352 COc1ccc(cc1)C1CC(O)(Oc2c(C)ccc(C)c12)c1ccccc1 InChI=1S/C24H24O3/c1-16-9-10-17(2)23-22(16)21(18-11-13-20(26-3)14-12-18)15-24(25,27-23)19-7-5-4-6-8-19/h4-14,21,25H,15H2,1-3H3 WYYQQTXSEYRJPH-UHFFFAOYSA-N 53405 4-(4-methoxyphenyl)-5,8-dimethyl-2-phenyl-3,4-dihydro-2H-1-benzopyran-2-ol::4-(4-methoxyphenyl)-5,8-dimethyl-2-phenyl-3,4-dihydrochromen-2-ol::4-(4-methoxyphenyl)-5,8-dimethyl-2-phenyl-chroman-2-ol::MLS000882588::PiF::SMR000465625::cid_16746506 Disintegrin and metalloproteinase domain-containing protein 17 69459 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53405&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16746506 123080222 ZINC13661765 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236353 COc1ccc(cc1)S(=O)(=O)Nc1ccc(Nc2ccccc2)cc1 InChI=1S/C19H18N2O3S/c1-24-18-11-13-19(14-12-18)25(22,23)21-17-9-7-16(8-10-17)20-15-5-3-2-4-6-15/h2-14,20-21H,1H3 MKFDTMOSDYAIGN-UHFFFAOYSA-N 114085 4-methoxy-N-(4-phenylazanylphenyl)benzenesulfonamide::MLS001179478::N-(4-anilinophenyl)-4-methoxy-benzenesulfonamide::N-(4-anilinophenyl)-4-methoxybenzenesulfonamide::SMR000476739::cid_1011074 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114085&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1011074 252663602 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236354 Clc1ccc(cc1)C1NC(=O)NC1=O InChI=1S/C9H7ClN2O2/c10-6-3-1-5(2-4-6)7-8(13)12-9(14)11-7/h1-4,7H,(H2,11,12,13,14) VPZYKVWVBSWFFL-UHFFFAOYSA-N 114086 5-(4-chlorophenyl)-2,4-imidazolidinedione::5-(4-chlorophenyl)hydantoin::5-(4-chlorophenyl)imidazolidine-2,4-dione::MLS001162990::SMR000498503::cid_97124 Disintegrin and metalloproteinase domain-containing protein 17 69386 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114086&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 97124 252663603 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236355 OCCCn1c(nc2cc(Cl)c(Cl)cc12)C1CCCN1c1nc(cs1)-c1ccc(F)cc1 InChI=1S/C23H21Cl2FN4OS/c24-16-11-18-21(12-17(16)25)29(9-2-10-31)22(27-18)20-3-1-8-30(20)23-28-19(13-32-23)14-4-6-15(26)7-5-14/h4-7,11-13,20,31H,1-3,8-10H2 GLVWXUSKTSISSX-UHFFFAOYSA-N 114087 3-(5,6-Dichloro-2-{1-[4-(4-fluoro-phenyl)-thiazol-2-yl]-pyrrolidin-2-yl}-benzoimidazol-1-yl)-propan-1-ol::3-[5,6-bis(chloranyl)-2-[1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]pyrrolidin-2-yl]benzimidazol-1-yl]propan-1-ol::3-[5,6-dichloro-2-[1-[4-(4-fluorophenyl)-1,3-thiazol-2-yl]pyrrolidin-2-yl]benzimidazol-1-yl]propan-1-ol::3-[5,6-dichloro-2-[1-[4-(4-fluorophenyl)-2-thiazolyl]-2-pyrrolidinyl]-1-benzimidazolyl]-1-propanol::3-[5,6-dichloro-2-[1-[4-(4-fluorophenyl)thiazol-2-yl]pyrrolidin-2-yl]benzimidazol-1-yl]propan-1-ol::MLS000911824::SMR000478101::cid_23724115 Disintegrin and metalloproteinase domain-containing protein 17 69459 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114087&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23724115 252663604 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236356 Oc1ccc(Cl)cc1NC(=O)C1CC(=NO1)c1c(F)cccc1Cl InChI=1S/C16H11Cl2FN2O3/c17-8-4-5-13(22)11(6-8)20-16(23)14-7-12(21-24-14)15-9(18)2-1-3-10(15)19/h1-6,14,22H,7H2,(H,20,23) LZHZADXYDXVUAV-UHFFFAOYSA-N 114088 3-(2-Chloro-6-fluoro-phenyl)-4,5-dihydro-isoxazole-5-carboxylic acid (5-chloro-2-hydroxy-phenyl)-amide::3-(2-chloranyl-6-fluoranyl-phenyl)-N-(5-chloranyl-2-oxidanyl-phenyl)-4,5-dihydro-1,2-oxazole-5-carboxamide::3-(2-chloro-6-fluoro-phenyl)-N-(5-chloro-2-hydroxy-phenyl)-2-isoxazoline-5-carboxamide::3-(2-chloro-6-fluorophenyl)-N-(5-chloro-2-hydroxyphenyl)-4,5-dihydro-1,2-oxazole-5-carboxamide::3-(2-chloro-6-fluorophenyl)-N-(5-chloro-2-hydroxyphenyl)-4,5-dihydroisoxazole-5-carboxamide::MLS001201452::SMR000524462::cid_3158030 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114088&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3158030 252663605 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236357 COc1ccc(cc1OC)-c1n[nH]c(=S)n1-c1ccc(Br)cc1 InChI=1S/C16H14BrN3O2S/c1-21-13-8-3-10(9-14(13)22-2)15-18-19-16(23)20(15)12-6-4-11(17)5-7-12/h3-9H,1-2H3,(H,19,23) DYHZMZSKDGVINI-UHFFFAOYSA-N 114089 4-(4-Bromo-phenyl)-5-(3,4-dimethoxy-phenyl)-4H-[1,2,4]triazole-3-thiol::4-(4-bromophenyl)-3-(3,4-dimethoxyphenyl)-1H-1,2,4-triazole-5-thione::MLS001208141::SMR000515793::cid_986193 Disintegrin and metalloproteinase domain-containing protein 17 41648 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114089&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 986193 252663606 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236358 CCSc1nsc(NC(=O)Nc2cccc(OC)c2)n1 InChI=1S/C12H14N4O2S2/c1-3-19-12-15-11(20-16-12)14-10(17)13-8-5-4-6-9(7-8)18-2/h4-7H,3H2,1-2H3,(H2,13,14,15,16,17) NAPMVEDRRXPHAP-UHFFFAOYSA-N 114090 1-(3-Ethylsulfanyl-[1,2,4]thiadiazol-5-yl)-3-(3-methoxy-phenyl)-urea::1-(3-ethylsulfanyl-1,2,4-thiadiazol-5-yl)-3-(3-methoxyphenyl)urea::1-[3-(ethylthio)-1,2,4-thiadiazol-5-yl]-3-(3-methoxyphenyl)urea::MLS001205987::SMR000504079::cid_3779521 Disintegrin and metalloproteinase domain-containing protein 17 69548 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114090&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3779521 252663607 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236359 Cc1ccc(CN2C(=O)[C@H]3Cc4c([nH]c5ccccc45)C(C)(C)N3C2=O)cc1 InChI=1S/C23H23N3O2/c1-14-8-10-15(11-9-14)13-25-21(27)19-12-17-16-6-4-5-7-18(16)24-20(17)23(2,3)26(19)22(25)28/h4-11,19,24H,12-13H2,1-3H3/t19-/m1/s1 XLHDISIHIXXBEP-LJQANCHMSA-N 114091 (3aR)-10,10-dimethyl-2-(4-methylbenzyl)-4,9-dihydro-3aH-imidazo[1,5-b]-carboline-1,3-quinone::MLS001065868::SMR000486357::cid_24747213 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114091 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114091&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24747213 252663608 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236360 COc1cccc(CN2C(=O)[C@@H]3Cc4c([nH]c5ccccc45)C(C)(C)N3C2=O)c1 InChI=1S/C23H23N3O3/c1-23(2)20-17(16-9-4-5-10-18(16)24-20)12-19-21(27)25(22(28)26(19)23)13-14-7-6-8-15(11-14)29-3/h4-11,19,24H,12-13H2,1-3H3/t19-/m0/s1 GZMDFKPAEJIEIJ-IBGZPJMESA-N 114092 (3aS)-2-m-anisyl-10,10-dimethyl-4,9-dihydro-3aH-imidazo[1,5-b]-carboline-1,3-quinone::MLS001065863::SMR000486352::cid_24747215 Disintegrin and metalloproteinase domain-containing protein 17 69431 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114092&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24747215 252663609 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236361 COC(=O)C1=C(C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(cc1)C(F)(F)F)c1cc2ccccc2s1 InChI=1S/C26H23F3N2O3S/c1-34-24(32)23-19(22-12-16-4-2-3-5-21(16)35-22)13-18-10-11-20(23)31(18)25(33)30-14-15-6-8-17(9-7-15)26(27,28)29/h2-9,12,18,20H,10-11,13-14H2,1H3,(H,30,33)/t18-,20+/m0/s1 IQZRCDVQSJNFCA-AZUAARDMSA-N 114093 (1S,5R)-3-(1-benzothiophen-2-yl)-8-[oxo-[[4-(trifluoromethyl)phenyl]methylamino]methyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::(1S,5R)-3-(benzothiophen-2-yl)-8-[[4-(trifluoromethyl)benzyl]carbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::MLS001065739::SMR000526002::cid_24747289::methyl (1S,5R)-3-(1-benzothiophen-2-yl)-8-[[4-(trifluoromethyl)phenyl]methylcarbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114093&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24747289 252663610 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236362 CCOc1ccc(-c2n[nH]cc2-c2ccc(Cl)cc2)c(O)c1 InChI=1S/C17H15ClN2O2/c1-2-22-13-7-8-14(16(21)9-13)17-15(10-19-20-17)11-3-5-12(18)6-4-11/h3-10,21H,2H2,1H3,(H,19,20) SYQLUJFPFXBQCC-UHFFFAOYSA-N 114094 (6Z)-6-[4-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]-3-ethoxy-1-cyclohexa-2,4-dienone::(6Z)-6-[4-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]-3-ethoxy-cyclohexa-2,4-dien-1-one::(6Z)-6-[4-(4-chlorophenyl)-1,2-dihydropyrazol-3-ylidene]-3-ethoxycyclohexa-2,4-dien-1-one::(6Z)-6-[4-(4-chlorophenyl)-3-pyrazolin-3-ylidene]-3-ethoxy-cyclohexa-2,4-dien-1-one::MLS001214927::SMR000543398::cid_5396873 Disintegrin and metalloproteinase domain-containing protein 17 69459 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114094&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5396873 252663611 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236363 COC(=O)c1ccc(CN2C(=O)C(C)N(C(=O)c3c(F)cccc3F)c3ccccc23)cc1 InChI=1S/C25H20F2N2O4/c1-15-23(30)28(14-16-10-12-17(13-11-16)25(32)33-2)20-8-3-4-9-21(20)29(15)24(31)22-18(26)6-5-7-19(22)27/h3-13,15H,14H2,1-2H3 SMBRYTPCKHXHRV-UHFFFAOYSA-N 90869 4-[[4-(2,6-difluorobenzoyl)-2-keto-3-methyl-3H-quinoxalin-1-yl]methyl]benzoic acid methyl ester::4-[[4-[(2,6-difluorophenyl)-oxomethyl]-3-methyl-2-oxo-3H-quinoxalin-1-yl]methyl]benzoic acid methyl ester::MLS001166280::SMR000549622::cid_3802707::methyl 4-[[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-3H-quinoxalin-1-yl]methyl]benzoate::methyl 4-[[4-[2,6-bis(fluoranyl)phenyl]carbonyl-3-methyl-2-oxidanylidene-3H-quinoxalin-1-yl]methyl]benzoate::methyl 4-{[4-(2,6-difluorobenzoyl)-3-methyl-2-oxo-3,4-dihydro-1(2H)-quinoxalinyl]methyl}benzenecarboxylate Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=90869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=90869&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3802707 252662418 ZINC01385987 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236364 [O-][N+](=O)CC(c1ccccc1)P(=O)(c1ccccc1)c1ccccc1 InChI=1S/C20H18NO3P/c22-21(23)16-20(17-10-4-1-5-11-17)25(24,18-12-6-2-7-13-18)19-14-8-3-9-15-19/h1-15,20H,16H2 RSCBLFUXRAXJQA-UHFFFAOYSA-N 65622 (1-diphenylphosphoryl-2-nitro-ethyl)benzene::(1-diphenylphosphoryl-2-nitroethyl)benzene::(2-nitro-1-phenylethyl)(diphenyl)phosphine oxide::MLS001198377::SMR000559168::cid_3666533 Disintegrin and metalloproteinase domain-containing protein 17 10942 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3666533 252644047 ZINC33354092 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236365 Cc1ccccc1-c1nnn(Cc2ccc(F)cc2Cl)n1 InChI=1S/C15H12ClFN4/c1-10-4-2-3-5-13(10)15-18-20-21(19-15)9-11-6-7-12(17)8-14(11)16/h2-8H,9H2,1H3 AASYFAORRVLNCI-UHFFFAOYSA-N 114095 2-(2-chloro-4-fluoro-benzyl)-5-(o-tolyl)tetrazole::2-(2-chloro-4-fluorobenzyl)-5-(2-methylphenyl)-2H-tetrazole::2-[(2-chloranyl-4-fluoranyl-phenyl)methyl]-5-(2-methylphenyl)-1,2,3,4-tetrazole::2-[(2-chloro-4-fluorophenyl)methyl]-5-(2-methylphenyl)tetrazole::MLS001198379::SMR000559188::cid_723279 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114095&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 723279 252663612 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236366 CN(Cc1ccc(F)cc1)C(=O)c1cccc(OCc2ccccc2)c1 InChI=1S/C22H20FNO2/c1-24(15-17-10-12-20(23)13-11-17)22(25)19-8-5-9-21(14-19)26-16-18-6-3-2-4-7-18/h2-14H,15-16H2,1H3 URIJDJJBECYGSA-UHFFFAOYSA-N 114096 3-benzoxy-N-(4-fluorobenzyl)-N-methyl-benzamide::MLS001176603::N-[(4-fluorophenyl)methyl]-N-methyl-3-phenylmethoxy-benzamide::N-[(4-fluorophenyl)methyl]-N-methyl-3-phenylmethoxybenzamide::SMR000589924::cid_4852866 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114096&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4852866 252663613 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236367 CN(c1ccc(OCc2ccc(cc2)[N+]([O-])=O)cc1)S(=O)(=O)c1ccccc1 InChI=1S/C20H18N2O5S/c1-21(28(25,26)20-5-3-2-4-6-20)17-11-13-19(14-12-17)27-15-16-7-9-18(10-8-16)22(23)24/h2-14H,15H2,1H3 KUJQDQINXXICPM-UHFFFAOYSA-N 114097 MLS001174682::N-methyl-N-[4-(4-nitrobenzyl)oxyphenyl]benzenesulfonamide::N-methyl-N-[4-[(4-nitrophenyl)methoxy]phenyl]benzenesulfonamide::SMR000591145::cid_4540064 Disintegrin and metalloproteinase domain-containing protein 17 69497 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114097&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4540064 252663614 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236368 NS(=O)(=O)c1ccc(cc1)\[NH+]=N\C=C\[CH-]c1ccccc1[N+]([O-])=O InChI=1S/C15H13N4O4S/c16-24(22,23)14-9-7-13(8-10-14)18-17-11-3-5-12-4-1-2-6-15(12)19(20)21/h1-11H,(H2,16,22,23)/q-1/p+1/b11-3+,18-17+ OODNEDLLGBHUTF-YREZNJBWSA-O 114098 4-[(2E)-2-[(E)-3-(2-nitrophenyl)prop-2-enylidene]hydrazinyl]benzenesulfonamide::4-[(N'E)-N'-[(E)-3-(2-nitrophenyl)prop-2-enylidene]hydrazino]benzenesulfonamide::MLS001171407::SMR000589934::cid_6892615 Disintegrin and metalloproteinase domain-containing protein 17 69508 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114098&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6892615 252663615 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236369 COc1ccc(NC(=O)C2CCN(CC2)S(=O)(=O)c2c(C)noc2\C=C\N(C)C)cc1 InChI=1S/C21H28N4O5S/c1-15-20(19(30-23-15)11-12-24(2)3)31(27,28)25-13-9-16(10-14-25)21(26)22-17-5-7-18(29-4)8-6-17/h5-8,11-12,16H,9-10,13-14H2,1-4H3,(H,22,26)/b12-11+ XUNPCJFPIMCFCQ-VAWYXSNFSA-N 114099 1-[5-[(E)-2-(dimethylamino)vinyl]-3-methyl-isoxazol-4-yl]sulfonyl-N-(4-methoxyphenyl)isonipecotamide::1-[[5-[(E)-2-(dimethylamino)ethenyl]-3-methyl-1,2-oxazol-4-yl]sulfonyl]-N-(4-methoxyphenyl)piperidine-4-carboxamide::1-[[5-[(E)-2-(dimethylamino)ethenyl]-3-methyl-4-isoxazolyl]sulfonyl]-N-(4-methoxyphenyl)-4-piperidinecarboxamide::MLS000925073::SMR000623947::cid_11655292 Disintegrin and metalloproteinase domain-containing protein 17 69497 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114099&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11655292 252663616 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236370 Nc1cc(OC(=O)c2c(F)cccc2Cl)nn1S(=O)(=O)c1ccccc1 InChI=1S/C16H11ClFN3O4S/c17-11-7-4-8-12(18)15(11)16(22)25-14-9-13(19)21(20-14)26(23,24)10-5-2-1-3-6-10/h1-9H,19H2 LLADYHMRJZVUFT-UHFFFAOYSA-N 114100 2-chloro-6-fluoro-benzoic acid (5-amino-1-besyl-pyrazol-3-yl) ester::2-chloro-6-fluorobenzoic acid [5-amino-1-(benzenesulfonyl)-3-pyrazolyl] ester::MLS000936166::SMR000620874::[5-amino-1-(benzenesulfonyl)pyrazol-3-yl] 2-chloro-6-fluorobenzoate::[5-azanyl-1-(phenylsulfonyl)pyrazol-3-yl] 2-chloranyl-6-fluoranyl-benzoate::cid_3376212 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114100&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3376212 252663617 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236371 Cc1c(sc2nc(C)nc(N3CCCCC3)c12)C(=O)Nc1ccc2OCCOc2c1 InChI=1S/C22H24N4O3S/c1-13-18-20(26-8-4-3-5-9-26)23-14(2)24-22(18)30-19(13)21(27)25-15-6-7-16-17(12-15)29-11-10-28-16/h6-7,12H,3-5,8-11H2,1-2H3,(H,25,27) JNKLPVCUGKIWTK-UHFFFAOYSA-N 61642 MLS001030562::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-4-(1-piperidinyl)-6-thieno[2,3-d]pyrimidinecarboxamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-4-piperidin-1-yl-thieno[2,3-d]pyrimidine-6-carboxamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-4-piperidin-1-ylthieno[2,3-d]pyrimidine-6-carboxamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2,5-dimethyl-4-piperidino-thieno[2,3-d]pyrimidine-6-carboxamide::SMR000635349::cid_4557537 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61642&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4557537 252640795 ZINC02924085 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236372 COc1ccc(cc1)C1=NS(=O)(=O)N(C)C(=C1)C(=O)Nc1ccc(C)cc1 InChI=1S/C19H19N3O4S/c1-13-4-8-15(9-5-13)20-19(23)18-12-17(21-27(24,25)22(18)2)14-6-10-16(26-3)11-7-14/h4-12H,1-3H3,(H,20,23) QPNXYLMMIVDJCA-UHFFFAOYSA-N 114101 1,1-diketo-5-(4-methoxyphenyl)-2-methyl-N-(p-tolyl)-1,2,6-thiadiazine-3-carboxamide::5-(4-methoxyphenyl)-2-methyl-N-(4-methylphenyl)-1,1-bis(oxidanylidene)-1,2,6-thiadiazine-3-carboxamide::5-(4-methoxyphenyl)-2-methyl-N-(4-methylphenyl)-1,1-dioxo-1,2,6-thiadiazine-3-carboxamide::MLS001115655::SMR000626260::cid_17253566 Disintegrin and metalloproteinase domain-containing protein 17 69483 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114101&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17253566 252663618 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236373 CN1C(=CC(=NS1(=O)=O)c1ccc(C)cc1)C(=O)Nc1ccc2OCOc2c1 InChI=1S/C19H17N3O5S/c1-12-3-5-13(6-4-12)15-10-16(22(2)28(24,25)21-15)19(23)20-14-7-8-17-18(9-14)27-11-26-17/h3-10H,11H2,1-2H3,(H,20,23) DFADCQLCXYMQHM-UHFFFAOYSA-N 114102 MLS001115702::N-(1,3-benzodioxol-5-yl)-1,1-diketo-2-methyl-5-(p-tolyl)-1,2,6-thiadiazine-3-carboxamide::N-(1,3-benzodioxol-5-yl)-2-methyl-5-(4-methylphenyl)-1,1-bis(oxidanylidene)-1,2,6-thiadiazine-3-carboxamide::N-(1,3-benzodioxol-5-yl)-2-methyl-5-(4-methylphenyl)-1,1-dioxo-1,2,6-thiadiazine-3-carboxamide::SMR000626235::cid_17253495 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114102&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17253495 252663619 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236374 Cc1cccc(N2CCN(CC2)C(=O)c2ccc(CS(=O)Cc3ccc(Cl)cc3)o2)c1C InChI=1S/C25H27ClN2O3S/c1-18-4-3-5-23(19(18)2)27-12-14-28(15-13-27)25(29)24-11-10-22(31-24)17-32(30)16-20-6-8-21(26)9-7-20/h3-11H,12-17H2,1-2H3 RLCWKPIUIKQGMO-UHFFFAOYSA-N 114103 MLS001123033::SMR000628049::[5-[(4-chlorobenzyl)sulfinylmethyl]-2-furyl]-[4-(2,3-dimethylphenyl)piperazino]methanone::[5-[(4-chlorophenyl)methylsulfinylmethyl]-2-furanyl]-[4-(2,3-dimethylphenyl)-1-piperazinyl]methanone::[5-[(4-chlorophenyl)methylsulfinylmethyl]furan-2-yl]-[4-(2,3-dimethylphenyl)piperazin-1-yl]methanone::cid_20899353 Disintegrin and metalloproteinase domain-containing protein 17 69489 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114103 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114103&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 20899353 252663620 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236375 COc1ccccc1CNS(=O)(=O)c1cc(ccc1C(C)C)-c1cc(C)no1 InChI=1S/C21H24N2O4S/c1-14(2)18-10-9-16(20-11-15(3)23-27-20)12-21(18)28(24,25)22-13-17-7-5-6-8-19(17)26-4/h5-12,14,22H,13H2,1-4H3 XHRMJUKRQNSAAI-UHFFFAOYSA-N 114104 2-isopropyl-5-(3-methylisoxazol-5-yl)-N-o-anisyl-benzenesulfonamide::MLS001096458::N-[(2-methoxyphenyl)methyl]-5-(3-methyl-1,2-oxazol-5-yl)-2-propan-2-yl-benzenesulfonamide::N-[(2-methoxyphenyl)methyl]-5-(3-methyl-1,2-oxazol-5-yl)-2-propan-2-ylbenzenesulfonamide::N-[(2-methoxyphenyl)methyl]-5-(3-methyl-5-isoxazolyl)-2-propan-2-ylbenzenesulfonamide::SMR000630477::cid_20936506 Disintegrin and metalloproteinase domain-containing protein 17 69495 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114104 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114104&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 20936506 252663621 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236376 Cc1ccc(cc1)S(=O)(=O)Nc1cc(Cl)c(O)c2ncccc12 InChI=1S/C16H13ClN2O3S/c1-10-4-6-11(7-5-10)23(21,22)19-14-9-13(17)16(20)15-12(14)3-2-8-18-15/h2-9,19-20H,1H3 VNDZMSRQSGKBEY-UHFFFAOYSA-N 88241 MLS001060650::N-(7-chloranyl-8-oxidanyl-quinolin-5-yl)-4-methyl-benzenesulfonamide::N-(7-chloro-8-hydroxy-5-quinolinyl)-4-methylbenzenesulfonamide::N-(7-chloro-8-hydroxy-5-quinolyl)-4-methyl-benzenesulfonamide::N-(7-chloro-8-hydroxyquinolin-5-yl)-4-methylbenzenesulfonamide::SMR000669628::cid_2140576 Disintegrin and metalloproteinase domain-containing protein 17 21231 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88241 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88241&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2140576 252660113 ZINC02697977 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236377 CC(OC(=O)c1cnc(C)cn1)C(=O)Nc1ccc2OCCOc2c1 InChI=1S/C17H17N3O5/c1-10-8-19-13(9-18-10)17(22)25-11(2)16(21)20-12-3-4-14-15(7-12)24-6-5-23-14/h3-4,7-9,11H,5-6H2,1-2H3,(H,20,21) BIJNMUSGNAYOTK-UHFFFAOYSA-N 114105 5-methyl-2-pyrazinecarboxylic acid [1-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-1-oxopropan-2-yl] ester::5-methylpyrazinic acid [2-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-2-keto-1-methyl-ethyl] ester::MLS001077400::SMR000712948::[1-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-1-oxidanylidene-propan-2-yl] 5-methylpyrazine-2-carboxylate::[1-(2,3-dihydro-1,4-benzodioxin-6-ylamino)-1-oxopropan-2-yl] 5-methylpyrazine-2-carboxylate::cid_6915444 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114105 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114105&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6915444 252663622 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236378 Clc1ccc(CNC(=S)Nc2ccncc2)cc1 InChI=1S/C13H12ClN3S/c14-11-3-1-10(2-4-11)9-16-13(18)17-12-5-7-15-8-6-12/h1-8H,9H2,(H2,15,16,17,18) HKLVXLJTGPHFMX-UHFFFAOYSA-N 114106 1-(4-chlorobenzyl)-3-(4-pyridyl)thiourea::1-[(4-chlorophenyl)methyl]-3-pyridin-4-yl-thiourea::1-[(4-chlorophenyl)methyl]-3-pyridin-4-ylthiourea::MLS001224678::SMR000679392::cid_969886 Disintegrin and metalloproteinase domain-containing protein 17 69590 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114106 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114106&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 969886 252663623 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236379 COc1cc(cc(OC)c1O)-c1nc(c([nH]1)-c1ccc2c(c1)-c1ccccc1S2(=O)=O)-c1ccccc1 InChI=1S/C29H22N2O5S/c1-35-22-15-19(16-23(36-2)28(22)32)29-30-26(17-8-4-3-5-9-17)27(31-29)18-12-13-25-21(14-18)20-10-6-7-11-24(20)37(25,33)34/h3-16,32H,1-2H3,(H,30,31) KZORXZDASHXLJR-UHFFFAOYSA-N 71876 4-[4-(5,5-Dioxo-5H-5lambda*6*-dibenzothiophen-2-yl)-5-phenyl-1H-imidazol-2-yl]-2,6-dimethoxy-phenol::4-[4-(5,5-diketodibenzothiophen-2-yl)-5-phenyl-4-imidazolin-2-ylidene]-2,6-dimethoxy-cyclohexa-2,5-dien-1-one::4-[4-(5,5-dioxo-2-dibenzothiophenyl)-5-phenyl-1,3-dihydroimidazol-2-ylidene]-2,6-dimethoxy-1-cyclohexa-2,5-dienone::4-[4-(5,5-dioxodibenzothiophen-2-yl)-5-phenyl-1,3-dihydroimidazol-2-ylidene]-2,6-dimethoxycyclohexa-2,5-dien-1-one::4-[4-[5,5-bis(oxidanylidene)dibenzothiophen-2-yl]-5-phenyl-1,3-dihydroimidazol-2-ylidene]-2,6-dimethoxy-cyclohexa-2,5-dien-1-one::MLS000068548::SMR000122999::cid_5763794 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=71876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=71876&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5763794 252649146 ZINC13124174 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236380 COc1ccc(cc1)S(=O)(=O)NCC(N1CCc2ccccc12)c1ccco1 InChI=1S/C21H22N2O4S/c1-26-17-8-10-18(11-9-17)28(24,25)22-15-20(21-7-4-14-27-21)23-13-12-16-5-2-3-6-19(16)23/h2-11,14,20,22H,12-13,15H2,1H3 NELCJKNSDRMOCK-UHFFFAOYSA-N 114107 MLS001237405::N-[2-(2,3-dihydroindol-1-yl)-2-(2-furanyl)ethyl]-4-methoxybenzenesulfonamide::N-[2-(2,3-dihydroindol-1-yl)-2-(furan-2-yl)ethyl]-4-methoxy-benzenesulfonamide::N-[2-(2,3-dihydroindol-1-yl)-2-(furan-2-yl)ethyl]-4-methoxybenzenesulfonamide::N-[2-(2-furyl)-2-indolin-1-yl-ethyl]-4-methoxy-benzenesulfonamide::SMR000811931::cid_16830238 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114107&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16830238 252663624 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236381 CN(C)c1ccc(NC(=O)c2ccc(COc3cccc(Cl)c3)o2)cc1 InChI=1S/C20H19ClN2O3/c1-23(2)16-8-6-15(7-9-16)22-20(24)19-11-10-18(26-19)13-25-17-5-3-4-14(21)12-17/h3-12H,13H2,1-2H3,(H,22,24) BZEQRMREWARERO-UHFFFAOYSA-N 50035 5-[(3-chloranylphenoxy)methyl]-N-[4-(dimethylamino)phenyl]furan-2-carboxamide::5-[(3-chlorophenoxy)methyl]-N-[4-(dimethylamino)phenyl]-2-furamide::5-[(3-chlorophenoxy)methyl]-N-[4-(dimethylamino)phenyl]-2-furancarboxamide::5-[(3-chlorophenoxy)methyl]-N-[4-(dimethylamino)phenyl]furan-2-carboxamide::MLS000043431::SMR000020248::cid_3241723 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3241723 252630307 ZINC04338360 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236382 COCCOc1ccc(cc1NC(=O)CN1C(=O)NC(C)(C1=O)c1ccc2OCOc2c1)C(F)(F)F InChI=1S/C23H22F3N3O7/c1-22(13-3-6-17-18(10-13)36-12-35-17)20(31)29(21(32)28-22)11-19(30)27-15-9-14(23(24,25)26)4-5-16(15)34-8-7-33-2/h3-6,9-10H,7-8,11-12H2,1-2H3,(H,27,30)(H,28,32) RPNXBPDTYSBOEQ-UHFFFAOYSA-N 114108 2-[4-(1,3-benzodioxol-5-yl)-2,5-diketo-4-methyl-imidazolidin-1-yl]-N-[2-(2-methoxyethoxy)-5-(trifluoromethyl)phenyl]acetamide::2-[4-(1,3-benzodioxol-5-yl)-4-methyl-2,5-bis(oxidanylidene)imidazolidin-1-yl]-N-[2-(2-methoxyethoxy)-5-(trifluoromethyl)phenyl]ethanamide::2-[4-(1,3-benzodioxol-5-yl)-4-methyl-2,5-dioxo-1-imidazolidinyl]-N-[2-(2-methoxyethoxy)-5-(trifluoromethyl)phenyl]acetamide::2-[4-(1,3-benzodioxol-5-yl)-4-methyl-2,5-dioxoimidazolidin-1-yl]-N-[2-(2-methoxyethoxy)-5-(trifluoromethyl)phenyl]acetamide::MLS001078520::SMR000706142::cid_16375659 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114108&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16375659 252663625 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236383 Cc1ccc(cc1NC(=O)CNc1ccc(cc1)C(F)(F)F)S(=O)(=O)N1CCCCC1 InChI=1S/C21H24F3N3O3S/c1-15-5-10-18(31(29,30)27-11-3-2-4-12-27)13-19(15)26-20(28)14-25-17-8-6-16(7-9-17)21(22,23)24/h5-10,13,25H,2-4,11-12,14H2,1H3,(H,26,28) UJQYLKZWCVBCQK-UHFFFAOYSA-N 114109 MLS001156714::N-(2-methyl-5-piperidin-1-ylsulfonyl-phenyl)-2-[[4-(trifluoromethyl)phenyl]amino]ethanamide::N-(2-methyl-5-piperidin-1-ylsulfonylphenyl)-2-[4-(trifluoromethyl)anilino]acetamide::N-(2-methyl-5-piperidinosulfonyl-phenyl)-2-[4-(trifluoromethyl)anilino]acetamide::N-[2-methyl-5-(1-piperidinylsulfonyl)phenyl]-2-[4-(trifluoromethyl)anilino]acetamide::SMR000711839::cid_24406489 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114109&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24406489 252663626 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236384 CC1CCCN(CCCNC(=O)c2coc3nc4ccccc4nc23)C1 InChI=1S/C20H24N4O2/c1-14-6-4-10-24(12-14)11-5-9-21-19(25)15-13-26-20-18(15)22-16-7-2-3-8-17(16)23-20/h2-3,7-8,13-14H,4-6,9-12H2,1H3,(H,21,25) RRVSPDDSBFXOAM-UHFFFAOYSA-N 51550 MLS000046706::N-[3-(3-methyl-1-piperidinyl)propyl]-3-furo[3,2-b]quinoxalinecarboxamide::N-[3-(3-methylpiperidin-1-yl)propyl]furo[2,3-b]quinoxaline-3-carboxamide::N-[3-(3-methylpiperidin-1-yl)propyl]furo[3,2-b]quinoxaline-3-carboxamide::N-[3-(3-methylpiperidino)propyl]furo[3,2-b]quinoxaline-3-carboxamide::SMR000032717::cid_3239334 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51550&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3239334 252631742 ZINC02849625 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236385 CCOC(=O)c1sc(NC(=O)CN2C(=O)NC3(CC(C)CC(C)(C)C3)C2=O)cc1C InChI=1S/C21H29N3O5S/c1-6-29-17(26)16-13(3)7-15(30-16)22-14(25)10-24-18(27)21(23-19(24)28)9-12(2)8-20(4,5)11-21/h7,12H,6,8-11H2,1-5H3,(H,22,25)(H,23,28) VWMFIYHYXVWQTN-UHFFFAOYSA-N 114110 3-methyl-5-[[1-oxo-2-(7,7,9-trimethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)ethyl]amino]-2-thiophenecarboxylic acid ethyl ester::5-[[2-(2,4-diketo-7,7,9-trimethyl-1,3-diazaspiro[4.5]decan-3-yl)acetyl]amino]-3-methyl-thiophene-2-carboxylic acid ethyl ester::MLS001157035::SMR000716521::cid_24982874::ethyl 3-methyl-5-[2-[7,7,9-trimethyl-2,4-bis(oxidanylidene)-1,3-diazaspiro[4.5]decan-3-yl]ethanoylamino]thiophene-2-carboxylate::ethyl 3-methyl-5-[[2-(7,7,9-trimethyl-2,4-dioxo-1,3-diazaspiro[4.5]decan-3-yl)acetyl]amino]thiophene-2-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114110&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24982874 252663627 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236386 CCCCCC(CC(=O)NO)C(=O)NC(C(C)C)C(=O)N1CCCC1CO InChI=1S/C19H35N3O5/c1-4-5-6-8-14(11-16(24)21-27)18(25)20-17(13(2)3)19(26)22-10-7-9-15(22)12-23/h13-15,17,23,27H,4-12H2,1-3H3,(H,20,25)(H,21,24) XJLATMLVMSFZBN-UHFFFAOYSA-N 50035245 CHEMBL67311::N*4*-Hydroxy-N*1*-[1-(2-hydroxymethyl-pyrrolidine-1-carbonyl)-2-methyl-propyl]-2-pentyl-succinamide::cid_2020 Disintegrin and metalloproteinase domain-containing protein 17 3592 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50035245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50035245&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search BB2 4Q4E,3U04,5JF1,6JET,1LQY,1G2A,4DR9,4JE7,3UWB,5MTE,5I2B,5NTH,4E9B,2OS1,2OS3,1IX1,5T8Z,5NJB,1WS1,6CK7,1SZZ,2OKL,5Y1X,2KMN,5CVQ,1Q1Y,1LRY,1LRU,3M6R,3M6P,3M6Q,4WXL,3PN4,3G5K,5VCP,5NSQ,6JF3,6JFC 2020 103943272 CHEMBL67311 ZINC03871393 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236387 Clc1ccc(cc1NC(=O)CN1C(=O)c2ccccc2S1(=O)=O)S(=O)(=O)N1CCCCC1 InChI=1S/C20H20ClN3O6S2/c21-16-9-8-14(31(27,28)23-10-4-1-5-11-23)12-17(16)22-19(25)13-24-20(26)15-6-2-3-7-18(15)32(24,29)30/h2-3,6-9,12H,1,4-5,10-11,13H2,(H,22,25) LVGFWLWDUZRJPB-UHFFFAOYSA-N 114111 MLS002158424::N-(2-chloranyl-5-piperidin-1-ylsulfonyl-phenyl)-2-[1,1,3-tris(oxidanylidene)-1,2-benzothiazol-2-yl]ethanamide::N-(2-chloro-5-piperidin-1-ylsulfonylphenyl)-2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetamide::N-(2-chloro-5-piperidinosulfonyl-phenyl)-2-(1,1,3-triketo-1,2-benzothiazol-2-yl)acetamide::N-[2-chloro-5-(1-piperidinylsulfonyl)phenyl]-2-(1,1,3-trioxo-1,2-benzothiazol-2-yl)acetamide::SMR001240895::cid_5029357 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114111 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114111&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5029357 252663628 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236388 COc1ccccc1N(C)S(=O)(=O)c1ccc(cc1)C(=O)NNC(=O)c1ccccc1O InChI=1S/C22H21N3O6S/c1-25(18-8-4-6-10-20(18)31-2)32(29,30)16-13-11-15(12-14-16)21(27)23-24-22(28)17-7-3-5-9-19(17)26/h3-14,26H,1-2H3,(H,23,27)(H,24,28) TXJQKPFFNCHVLF-UHFFFAOYSA-N 96402 4-[[(2-hydroxybenzoyl)amino]carbamoyl]-N-(2-methoxyphenyl)-N-methylbenzenesulfonamide::4-[[(2-hydroxyphenyl)carbonylamino]carbamoyl]-N-(2-methoxyphenyl)-N-methyl-benzenesulfonamide::4-[[[(2-hydroxyphenyl)-oxomethyl]hydrazo]-oxomethyl]-N-(2-methoxyphenyl)-N-methylbenzenesulfonamide::MLS002164709::N-(2-methoxyphenyl)-N-methyl-4-[(salicyloylamino)carbamoyl]benzenesulfonamide::SMR001247080::cid_4786878 Disintegrin and metalloproteinase domain-containing protein 17 69512 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96402&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4786878 164037646 ZINC09438839 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236389 COc1ccc(OC)c(c1)-c1csc(NC(=O)COC(=O)C2(C)CC2(Cl)Cl)n1 InChI=1S/C18H18Cl2N2O5S/c1-17(9-18(17,19)20)15(24)27-7-14(23)22-16-21-12(8-28-16)11-6-10(25-2)4-5-13(11)26-3/h4-6,8H,7,9H2,1-3H3,(H,21,22,23) BBRCOGZTSSSDMU-UHFFFAOYSA-N 114112 2,2-dichloro-1-methyl-1-cyclopropanecarboxylic acid [2-[[4-(2,5-dimethoxyphenyl)-2-thiazolyl]amino]-2-oxoethyl] ester::2,2-dichloro-1-methyl-cyclopropanecarboxylic acid [2-[[4-(2,5-dimethoxyphenyl)thiazol-2-yl]amino]-2-keto-ethyl] ester::MLS002183040::SMR001272070::[2-[[4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-yl]amino]-2-oxidanylidene-ethyl] 2,2-bis(chloranyl)-1-methyl-cyclopropane-1-carboxylate::[2-[[4-(2,5-dimethoxyphenyl)-1,3-thiazol-2-yl]amino]-2-oxoethyl] 2,2-dichloro-1-methylcyclopropane-1-carboxylate::cid_25162710 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114112 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114112&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25162710 252663629 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236390 CCc1noc(C)c1C(=O)OC(C)C(=O)Nc1ccc2OCOc2c1 InChI=1S/C17H18N2O6/c1-4-12-15(9(2)25-19-12)17(21)24-10(3)16(20)18-11-5-6-13-14(7-11)23-8-22-13/h5-7,10H,4,8H2,1-3H3,(H,18,20) HDHAELXUMRQKAC-UHFFFAOYSA-N 114113 3-ethyl-5-methyl-4-isoxazolecarboxylic acid [1-(1,3-benzodioxol-5-ylamino)-1-oxopropan-2-yl] ester::3-ethyl-5-methyl-isoxazole-4-carboxylic acid [2-(1,3-benzodioxol-5-ylamino)-2-keto-1-methyl-ethyl] ester::MLS002163336::SMR001245726::[1-(1,3-benzodioxol-5-ylamino)-1-oxidanylidene-propan-2-yl] 3-ethyl-5-methyl-1,2-oxazole-4-carboxylate::[1-(1,3-benzodioxol-5-ylamino)-1-oxopropan-2-yl] 3-ethyl-5-methyl-1,2-oxazole-4-carboxylate::cid_16305627 Disintegrin and metalloproteinase domain-containing protein 17 69555 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114113 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114113&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16305627 252663630 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236391 CCN(CC)S(=O)(=O)c1cc(NC(=O)Cc2ccc(s2)S(=O)(=O)N2CCOCC2)ccc1Cl InChI=1S/C20H26ClN3O6S3/c1-3-23(4-2)32(26,27)18-13-15(5-7-17(18)21)22-19(25)14-16-6-8-20(31-16)33(28,29)24-9-11-30-12-10-24/h5-8,13H,3-4,9-12,14H2,1-2H3,(H,22,25) WEUSJJGHXMVCOA-UHFFFAOYSA-N 114114 MLS002180418::N-[4-chloranyl-3-(diethylsulfamoyl)phenyl]-2-(5-morpholin-4-ylsulfonylthiophen-2-yl)ethanamide::N-[4-chloro-3-(diethylsulfamoyl)phenyl]-2-(5-morpholin-4-ylsulfonylthiophen-2-yl)acetamide::N-[4-chloro-3-(diethylsulfamoyl)phenyl]-2-(5-morpholinosulfonyl-2-thienyl)acetamide::N-[4-chloro-3-(diethylsulfamoyl)phenyl]-2-[5-(4-morpholinylsulfonyl)-2-thiophenyl]acetamide::SMR001269448::cid_25163202 Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114114 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114114&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25163202 252663631 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236392 O=C(NCC1COc2ccccc2O1)c1cccc(c1)S(=O)(=O)N1CCN(CC1)c1ccccc1 InChI=1S/C26H27N3O5S/c30-26(27-18-22-19-33-24-11-4-5-12-25(24)34-22)20-7-6-10-23(17-20)35(31,32)29-15-13-28(14-16-29)21-8-2-1-3-9-21/h1-12,17,22H,13-16,18-19H2,(H,27,30) MIWIYMLUONZKFP-UHFFFAOYSA-N 114115 MLS002156327::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-(4-phenylpiperazin-1-yl)sulfonyl-benzamide::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-(4-phenylpiperazin-1-yl)sulfonylbenzamide::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-(4-phenylpiperazino)sulfonyl-benzamide::N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-[(4-phenyl-1-piperazinyl)sulfonyl]benzamide::SMR001238833::cid_4803920 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114115 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114115&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4803920 252663632 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236393 CN(CC(=O)Nc1cccc(F)c1)C(=O)c1ccccc1OCc1cccc(C)c1 InChI=1S/C24H23FN2O3/c1-17-7-5-8-18(13-17)16-30-22-12-4-3-11-21(22)24(29)27(2)15-23(28)26-20-10-6-9-19(25)14-20/h3-14H,15-16H2,1-2H3,(H,26,28) ZYNZURIRCRZOGM-UHFFFAOYSA-N 114116 MLS002182601::N-[2-(3-fluoroanilino)-2-keto-ethyl]-N-methyl-2-(3-methylbenzyl)oxy-benzamide::N-[2-(3-fluoroanilino)-2-oxoethyl]-N-methyl-2-[(3-methylphenyl)methoxy]benzamide::N-[2-[(3-fluorophenyl)amino]-2-oxidanylidene-ethyl]-N-methyl-2-[(3-methylphenyl)methoxy]benzamide::SMR001271631::cid_25163690 Disintegrin and metalloproteinase domain-containing protein 17 69510 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114116 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114116&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25163690 252663633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236394 COc1ccc(S[C@@H](CCN2CC[C@H](C)CCC2=O)c2ccccc2)cc1 InChI=1S/C23H29NO2S/c1-18-8-13-23(25)24(16-14-18)17-15-22(19-6-4-3-5-7-19)27-21-11-9-20(26-2)10-12-21/h3-7,9-12,18,22H,8,13-17H2,1-2H3/t18-,22+/m1/s1 BGWZLKCQMHOANC-GCJKJVERSA-N 114117 (5R)-1-[(3S)-3-(4-methoxyphenyl)sulfanyl-3-phenyl-propyl]-5-methyl-azepan-2-one::(5R)-1-[(3S)-3-(4-methoxyphenyl)sulfanyl-3-phenylpropyl]-5-methylazepan-2-one::(5R)-1-[(3S)-3-[(4-methoxyphenyl)thio]-3-phenyl-propyl]-5-methyl-azepan-2-one::(5R)-1-[(3S)-3-[(4-methoxyphenyl)thio]-3-phenylpropyl]-5-methyl-2-azepanone::MLS002222476::SMR001307391::cid_42628516 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114117 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114117&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 42628516 252663634 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236395 Cc1ccc2OC[C@H]3[C@@H](N4C(=O)CN(Cc5ccc(Cl)cc5)C(=O)[C@@]4(C)[C@H]3c3ccccc3)c2c1 InChI=1S/C29H27ClN2O3/c1-18-8-13-24-22(14-18)27-23(17-35-24)26(20-6-4-3-5-7-20)29(2)28(34)31(16-25(33)32(27)29)15-19-9-11-21(30)12-10-19/h3-14,23,26-27H,15-17H2,1-2H3/t23-,26+,27+,29-/m1/s1 VDANWUIZWUZMIF-CHRXXPTBSA-N 114118 MLS002425461::SMR001371387::cid_44142832 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114118 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114118&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44142832 242053893 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236396 COC(=O)C1=C(C[C@@H]2CC[C@H]1N2C(=O)NCc1cccc(c1)C(F)(F)F)c1ccc(F)cc1OCc1ccccc1 InChI=1S/C31H28F4N2O4/c1-40-29(38)28-25(24-12-10-22(32)15-27(24)41-18-19-6-3-2-4-7-19)16-23-11-13-26(28)37(23)30(39)36-17-20-8-5-9-21(14-20)31(33,34)35/h2-10,12,14-15,23,26H,11,13,16-18H2,1H3,(H,36,39)/t23-,26+/m0/s1 JVMVEQRZBCXSCK-JYFHCDHNSA-N 114119 (1S,5R)-3-(2-benzoxy-4-fluoro-phenyl)-8-[[3-(trifluoromethyl)benzyl]carbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::(1S,5R)-3-(4-fluoro-2-phenylmethoxyphenyl)-8-[oxo-[[3-(trifluoromethyl)phenyl]methylamino]methyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::MLS002472181::SMR001395332::cid_44144105::methyl (1S,5R)-3-(4-fluoranyl-2-phenylmethoxy-phenyl)-8-[[3-(trifluoromethyl)phenyl]methylcarbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylate::methyl (1S,5R)-3-(4-fluoro-2-phenylmethoxyphenyl)-8-[[3-(trifluoromethyl)phenyl]methylcarbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114119&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44144105 252663635 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236397 COC(=O)C1=C(C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(Cl)cc1)c1ccccc1OCc1ccccc1 InChI=1S/C30H29ClN2O4/c1-36-29(34)28-25(24-9-5-6-10-27(24)37-19-21-7-3-2-4-8-21)17-23-15-16-26(28)33(23)30(35)32-18-20-11-13-22(31)14-12-20/h2-14,23,26H,15-19H2,1H3,(H,32,35)/t23-,26+/m0/s1 QQUVJBKLZUNMRK-JYFHCDHNSA-N 114120 (1S,5R)-3-(2-benzoxyphenyl)-8-[(4-chlorobenzyl)carbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::(1S,5R)-8-[[(4-chlorophenyl)methylamino]-oxomethyl]-3-(2-phenylmethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::MLS002472203::SMR001395354::cid_44144127::methyl (1S,5R)-8-[(4-chlorophenyl)methylcarbamoyl]-3-(2-phenylmethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114120&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44144127 252663636 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236398 COC(=O)C1=C(C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccc(OC)cc1)c1cccc(OCc2ccccc2)c1 InChI=1S/C32H34N2O6/c1-37-25-12-14-26(15-13-25)39-18-17-33-32(36)34-24-11-16-29(34)30(31(35)38-2)28(20-24)23-9-6-10-27(19-23)40-21-22-7-4-3-5-8-22/h3-10,12-15,19,24,29H,11,16-18,20-21H2,1-2H3,(H,33,36)/t24-,29+/m0/s1 ZURBAOIVZQGZPB-PWUYWRBVSA-N 114121 (1S,5R)-3-(3-benzoxyphenyl)-8-[2-(4-methoxyphenoxy)ethylcarbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::(1S,5R)-8-[[2-(4-methoxyphenoxy)ethylamino]-oxomethyl]-3-(3-phenylmethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::MLS002472219::SMR001395370::cid_44144143::methyl (1S,5R)-8-[2-(4-methoxyphenoxy)ethylcarbamoyl]-3-(3-phenylmethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114121 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114121&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44144143 252663637 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236399 OC[C@H](Cc1ccccc1)NC(=O)C[C@@H](CC=C)C(=O)N1CCC[C@H]1COC(=O)[C@@H](CCC=C)Cc1ccc(F)cc1 InChI=1S/C34H43FN2O5/c1-3-5-13-28(20-26-15-17-29(35)18-16-26)34(41)42-24-31-14-9-19-37(31)33(40)27(10-4-2)22-32(39)36-30(23-38)21-25-11-7-6-8-12-25/h3-4,6-8,11-12,15-18,27-28,30-31,38H,1-2,5,9-10,13-14,19-24H2,(H,36,39)/t27-,28+,30+,31+/m1/s1 VMUUBLNWZMGROU-AXXAOYNRSA-N 114122 (2S)-2-(4-fluorobenzyl)hex-5-enoic acid [(2S)-1-[(2R)-2-[2-[[(1S)-1-benzyl-2-hydroxy-ethyl]amino]-2-keto-ethyl]pent-4-enoyl]pyrrolidin-2-yl]methyl ester::(2S)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2S)-1-[(2R)-2-[2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]-1-oxopent-4-enyl]-2-pyrrolidinyl]methyl ester::MLS002319869::SMR001337493::[(2S)-1-[(2R)-2-[2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]pent-4-enoyl]pyrrolidin-2-yl]methyl (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2S)-1-[(2R)-2-[2-oxidanylidene-2-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]ethyl]pent-4-enoyl]pyrrolidin-2-yl]methyl (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201441 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114122&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201441 252663638 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236400 OC[C@H](Cc1ccccc1)NC(=O)C[C@H]1C\C=C/CC[C@@H](Cc2ccc(F)cc2)C(=O)O[C@H](CNC1=O)c1ccccc1 InChI=1S/C35H39FN2O5/c36-30-18-16-26(17-19-30)20-29-15-9-3-8-14-28(22-33(40)38-31(24-39)21-25-10-4-1-5-11-25)34(41)37-23-32(43-35(29)42)27-12-6-2-7-13-27/h1-8,10-13,16-19,28-29,31-32,39H,9,14-15,20-24H2,(H,37,41)(H,38,40)/b8-3-/t28-,29+,31+,32-/m1/s1 OURCUTDTVPFQQW-CXMFYOGJSA-N 114123 2-[(2S,6R,8Z,12S)-12-[(4-fluorophenyl)methyl]-5,13-bis(oxidanylidene)-2-phenyl-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]ethanamide::2-[(2S,6R,8Z,12S)-12-[(4-fluorophenyl)methyl]-5,13-dioxo-2-phenyl-1-oxa-4-azacyclotridec-8-en-6-yl]-N-[(2S)-1-hydroxy-3-phenylpropan-2-yl]acetamide::MLS002320044::N-[(1S)-1-benzyl-2-hydroxy-ethyl]-2-[(2S,6R,8Z,12S)-12-(4-fluorobenzyl)-5,13-diketo-2-phenyl-1-oxa-4-azacyclotridec-8-en-6-yl]acetamide::SMR001337669::cid_44201608 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114123&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201608 252663639 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236401 OC[C@H](Cc1ccccc1)NC(=O)C[C@H](CC=C)C(=O)N[C@H](COC(=O)[C@H](CCC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C40H46FN3O5/c1-3-5-14-31(21-29-17-19-33(41)20-18-29)40(48)49-27-35(23-32-25-42-37-16-10-9-15-36(32)37)44-39(47)30(11-4-2)24-38(46)43-34(26-45)22-28-12-7-6-8-13-28/h3-4,6-10,12-13,15-20,25,30-31,34-35,42,45H,1-2,5,11,14,21-24,26-27H2,(H,43,46)(H,44,47)/t30-,31+,34-,35-/m0/s1 NVFBPXDALITKAR-GXFPKFJOSA-N 113933 (2R)-2-(4-fluorobenzyl)hex-5-enoic acid [(2S)-2-[[(2S)-2-[2-[[(1S)-1-benzyl-2-hydroxy-ethyl]amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2R)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2S)-2-[[(2S)-2-[2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002320341::SMR001337966::[(2S)-2-[[(2S)-2-[2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2S)-3-(1H-indol-3-yl)-2-[[(2S)-2-[2-oxidanylidene-2-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]ethyl]pent-4-enoyl]amino]propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201842 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113933&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201842 252663461 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236402 COc1ccc(NC(=O)Nc2ccc3O[C@H](CN(C)S(=O)(=O)c4cccs4)[C@H](C)CN([C@@H](C)CO)C(=O)c3c2)cc1 InChI=1S/C28H34N4O7S2/c1-18-15-32(19(2)17-33)27(34)23-14-21(30-28(35)29-20-7-10-22(38-4)11-8-20)9-12-24(23)39-25(18)16-31(3)41(36,37)26-6-5-13-40-26/h5-14,18-19,25,33H,15-17H2,1-4H3,(H2,29,30,35)/t18-,19+,25-/m1/s1 MEYAITLLUVMHFV-HHJKRLRDSA-N 114124 1-(4-methoxyphenyl)-3-[(2S,3R)-3-methyl-2-[[methyl(thiophen-2-ylsulfonyl)amino]methyl]-6-oxidanylidene-5-[(2S)-1-oxidanylpropan-2-yl]-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]urea::1-[(2S,3R)-5-[(1S)-2-hydroxy-1-methyl-ethyl]-6-keto-3-methyl-2-[[methyl(2-thienylsulfonyl)amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea::1-[(2S,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(thiophen-2-ylsulfonyl)amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]-3-(4-methoxyphenyl)urea::MLS002474477::SMR001398638::cid_44202702 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114124&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44202702 252663640 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236403 C[C@H](CO)N1C[C@H](C)[C@H](CN(C)S(=O)(=O)c2cccs2)Oc2ccc(NC(=O)Nc3ccc4OCOc4c3)cc2CC1=O InChI=1S/C29H34N4O8S2/c1-18-14-33(19(2)16-34)27(35)12-20-11-21(30-29(36)31-22-7-9-24-25(13-22)40-17-39-24)6-8-23(20)41-26(18)15-32(3)43(37,38)28-5-4-10-42-28/h4-11,13,18-19,26,34H,12,14-17H2,1-3H3,(H2,30,31,36)/t18-,19+,26-/m0/s1 FTXPGJSZMBKNDZ-ANSQWYIGSA-N 114125 1-(1,3-benzodioxol-5-yl)-3-[(2R,3S)-3-methyl-2-[[methyl(thiophen-2-ylsulfonyl)amino]methyl]-6-oxidanylidene-5-[(2R)-1-oxidanylpropan-2-yl]-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]urea::1-(1,3-benzodioxol-5-yl)-3-[(2R,3S)-5-[(1R)-2-hydroxy-1-methyl-ethyl]-6-keto-3-methyl-2-[[methyl(2-thienylsulfonyl)amino]methyl]-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]urea::1-(1,3-benzodioxol-5-yl)-3-[(2R,3S)-5-[(2R)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl(thiophen-2-ylsulfonyl)amino]methyl]-6-oxo-2,3,4,7-tetrahydro-1,5-benzoxazonin-9-yl]urea::MLS002474124::SMR001398285::cid_44202765 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114125&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44202765 252663641 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236404 COc1ccc(CNC(=O)CN(Cc2ccc(Cl)cc2)S(=O)(=O)c2ccccc2)cc1 InChI=1S/C23H23ClN2O4S/c1-30-21-13-9-18(10-14-21)15-25-23(27)17-26(16-19-7-11-20(24)12-8-19)31(28,29)22-5-3-2-4-6-22/h2-14H,15-17H2,1H3,(H,25,27) IMNQHPILJNJHSI-UHFFFAOYSA-N 66340 2-[(4-chlorophenyl)methyl-(phenylsulfonyl)amino]-N-[(4-methoxyphenyl)methyl]ethanamide::2-[benzenesulfonyl-[(4-chlorophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide::2-[besyl-(4-chlorobenzyl)amino]-N-p-anisyl-acetamide::MLS000531277::N~2~-(4-chlorobenzyl)-N~1~-(4-methoxybenzyl)-N~2~-(phenylsulfonyl)glycinamide::SMR000136255::cid_1331390 Disintegrin and metalloproteinase domain-containing protein 17 69456 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66340&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1331390 252644665 ZINC01163566 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236405 COc1cc(ccc1OCc1ccc(cc1)[N+]([O-])=O)C(c1c(C)[nH][nH]c1=O)c1c(C)[nH][nH]c1=O InChI=1S/C23H19N5O6/c1-12-19(22(29)26-24-12)21(20-13(2)25-27-23(20)30)15-6-9-17(18(10-15)33-3)34-11-14-4-7-16(8-5-14)28(31)32/h4-10,21H,11H2,1-3H3 KEWNWLKEHDFWNV-UHFFFAOYSA-N 70598 4,4'-({3-methoxy-4-[(4-nitrobenzyl)oxy]phenyl}methylene)bis(3-methyl-1H-pyrazol-5-ol)::4-[(3-keto-5-methyl-3-pyrazolin-4-yl)-[3-methoxy-4-(4-nitrobenzyl)oxy-phenyl]methyl]-5-methyl-3-pyrazolin-3-one::4-[[3-methoxy-4-[(4-nitrophenyl)methoxy]phenyl]-(3-methyl-5-oxidanylidene-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one::4-[[3-methoxy-4-[(4-nitrophenyl)methoxy]phenyl]-(3-methyl-5-oxo-1,2-dihydropyrazol-4-yl)methyl]-5-methyl-1,2-dihydropyrazol-3-one::MLS000530767::SMR000135805::cid_2913459 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=70598 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=70598&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2913459 252648616 ZINC19940242 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236406 CCOC(=O)c1ccc(NC(=O)C2CCCN(C2)S(=O)(=O)c2ccc(F)cc2)cc1 InChI=1S/C21H23FN2O5S/c1-2-29-21(26)15-5-9-18(10-6-15)23-20(25)16-4-3-13-24(14-16)30(27,28)19-11-7-17(22)8-12-19/h5-12,16H,2-4,13-14H2,1H3,(H,23,25) RKGMMDHXCGCHAQ-UHFFFAOYSA-N 114126 4-[[1-(4-fluorophenyl)sulfonylnipecotoyl]amino]benzoic acid ethyl ester::4-[[[1-(4-fluorophenyl)sulfonyl-3-piperidinyl]-oxomethyl]amino]benzoic acid ethyl ester::MLS002548518::SMR000136755::cid_2979567::ethyl 4-[({1-[(4-fluorophenyl)sulfonyl]-3-piperidinyl}carbonyl)amino]benzoate::ethyl 4-[[1-(4-fluorophenyl)sulfonylpiperidin-3-yl]carbonylamino]benzoate::ethyl 4-[[1-(4-fluorophenyl)sulfonylpiperidine-3-carbonyl]amino]benzoate Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114126&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2979567 252663642 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236407 [O-][N+](=O)c1ccc(cc1)[C@@H]1[C-](N[N+](=C1C(=O)N1CCOC1=O)c1ccc(Br)cc1)c1ccccc1 InChI=1S/C25H19BrN4O5/c26-18-8-12-19(13-9-18)29-23(24(31)28-14-15-35-25(28)32)21(16-6-10-20(11-7-16)30(33)34)22(27-29)17-4-2-1-3-5-17/h1-13,21,27H,14-15H2/t21-/m1/s1 MEONXDYZBGYUAW-OAQYLSRUSA-N 114127 3-[(3R,4S)-2-(4-bromophenyl)-4-(4-nitrophenyl)-5-phenyl-2-pyrazoline-3-carbonyl]oxazolidin-2-one::3-[(3R,4S)-2-(4-bromophenyl)-4-(4-nitrophenyl)-5-phenyl-3,4-dihydropyrazole-3-carbonyl]-1,3-oxazolidin-2-one::3-[[(3R,4S)-2-(4-bromophenyl)-4-(4-nitrophenyl)-5-phenyl-3,4-dihydropyrazol-3-yl]-oxomethyl]-2-oxazolidinone::3-[[(3R,4S)-2-(4-bromophenyl)-4-(4-nitrophenyl)-5-phenyl-3,4-dihydropyrazol-3-yl]carbonyl]-1,3-oxazolidin-2-one::MLS000517949::SMR000327268::cid_16060006 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114127&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899707 252663643 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236408 Cc1cc2oc(=O)cc(-c3ccccc3)c2c(C)c1-c1ccc(O)cc1 InChI=1S/C23H18O3/c1-14-12-20-23(15(2)22(14)17-8-10-18(24)11-9-17)19(13-21(25)26-20)16-6-4-3-5-7-16/h3-13,24H,1-2H3 KZUXZSFZKWQYQT-UHFFFAOYSA-N 91349 6-(4-hydroxyphenyl)-5,7-dimethyl-4-phenyl-1-benzopyran-2-one::6-(4-hydroxyphenyl)-5,7-dimethyl-4-phenyl-chromen-2-one::6-(4-hydroxyphenyl)-5,7-dimethyl-4-phenyl-coumarin::6-(4-hydroxyphenyl)-5,7-dimethyl-4-phenylchromen-2-one::MLS000518101::SMR000327110::cid_6540213 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=91349 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=91349&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6540213 252662884 ZINC13813939 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236409 Clc1ccc(CC2(NC(=O)NC2=O)c2ccccc2)cc1 InChI=1S/C16H13ClN2O2/c17-13-8-6-11(7-9-13)10-16(12-4-2-1-3-5-12)14(20)18-15(21)19-16/h1-9H,10H2,(H2,18,19,20,21) LUDKHCBYFRDZCK-UHFFFAOYSA-N 114128 5-(4-chlorobenzyl)-5-phenyl-hydantoin::5-[(4-chlorophenyl)methyl]-5-phenyl-imidazolidine-2,4-dione::5-[(4-chlorophenyl)methyl]-5-phenylimidazolidine-2,4-dione::MLS002608114::SMR001526865::cid_236330 Disintegrin and metalloproteinase domain-containing protein 17 3672 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114128&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 236330 252663644 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236410 CCOC(=O)C1=CN(Cc2cccc(F)c2)S(=O)(=O)NC1c1ccc2ccccc2c1 InChI=1S/C23H21FN2O4S/c1-2-30-23(27)21-15-26(14-16-6-5-9-20(24)12-16)31(28,29)25-22(21)19-11-10-17-7-3-4-8-18(17)13-19/h3-13,15,22,25H,2,14H2,1H3 OZLPRNGNHWYVRI-UHFFFAOYSA-N 114129 6-(3-fluorobenzyl)-1,1-diketo-3-(2-naphthyl)-2,3-dihydro-1,2,6-thiadiazine-4-carboxylic acid ethyl ester::6-[(3-fluorophenyl)methyl]-3-(2-naphthalenyl)-1,1-dioxo-2,3-dihydro-1,2,6-thiadiazine-4-carboxylic acid ethyl ester::MLS002603746::SMR001522476::cid_42627986::ethyl 6-[(3-fluorophenyl)methyl]-3-naphthalen-2-yl-1,1-bis(oxidanylidene)-2,3-dihydro-1,2,6-thiadiazine-4-carboxylate::ethyl 6-[(3-fluorophenyl)methyl]-3-naphthalen-2-yl-1,1-dioxo-2,3-dihydro-1,2,6-thiadiazine-4-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114129&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 42627986 252663645 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236411 Oc1cc([O-])ccc1\C=[NH+]\NC(=O)C(CSCc1ccccc1)NC(=O)c1ccc(cc1)[N+]([O-])=O InChI=1S/C24H22N4O6S/c29-20-11-8-18(22(30)12-20)13-25-27-24(32)21(15-35-14-16-4-2-1-3-5-16)26-23(31)17-6-9-19(10-7-17)28(33)34/h1-13,21,29-30H,14-15H2,(H,26,31)(H,27,32)/b25-13+ KOCUHNADGOJUPA-DHRITJCHSA-N 114130 4-nitro-N-[1-oxidanylidene-1-[2-[(E)-(2-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-3-(phenylmethylsulfanyl)propan-2-yl]benzamide::MLS002585760::N-[1-[(benzylthio)methyl]-2-[N'-[(E)-(2-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-2-keto-ethyl]-4-nitro-benzamide::N-[1-[[(E)-(2-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]hydrazo]-1-oxo-3-(phenylmethylthio)propan-2-yl]-4-nitrobenzamide::N-[3-benzylsulfanyl-1-[2-[(E)-(2-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-1-oxopropan-2-yl]-4-nitrobenzamide::SMR000131945::cid_9551407 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114130&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9551407 252663646 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236412 CCCCN(Cc1ccccc1)S(=O)(=O)c1cc2N(C(C)Cc2cc1Br)C(C)=O InChI=1S/C22H27BrN2O3S/c1-4-5-11-24(15-18-9-7-6-8-10-18)29(27,28)22-14-21-19(13-20(22)23)12-16(2)25(21)17(3)26/h6-10,13-14,16H,4-5,11-12,15H2,1-3H3 CVFUETLCFVWKPL-UHFFFAOYSA-N 114131 1-acetyl-5-bromo-N-butyl-2-methyl-N-(phenylmethyl)-2,3-dihydroindole-6-sulfonamide::1-acetyl-N-benzyl-5-bromo-N-butyl-2-methyl-2,3-dihydroindole-6-sulfonamide::1-acetyl-N-benzyl-5-bromo-N-butyl-2-methyl-indoline-6-sulfonamide::5-bromanyl-N-butyl-1-ethanoyl-2-methyl-N-(phenylmethyl)-2,3-dihydroindole-6-sulfonamide::MLS002586059::SMR001496778::cid_44601843 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114131&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44601843 252663647 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236413 COc1cccc(c1)C(=O)c1c(ncc2cc(OC)c(OC)cc12)-c1ccccc1 InChI=1S/C25H21NO4/c1-28-19-11-7-10-17(12-19)25(27)23-20-14-22(30-3)21(29-2)13-18(20)15-26-24(23)16-8-5-4-6-9-16/h4-15H,1-3H3 DCRJFLHNZRDYMM-UHFFFAOYSA-N 114132 (6,7-dimethoxy-3-phenyl-4-isoquinolinyl)-(3-methoxyphenyl)methanone::(6,7-dimethoxy-3-phenyl-4-isoquinolyl)-(3-methoxyphenyl)methanone::(6,7-dimethoxy-3-phenyl-isoquinolin-4-yl)-(3-methoxyphenyl)methanone::(6,7-dimethoxy-3-phenylisoquinolin-4-yl)-(3-methoxyphenyl)methanone::MLS002603252::SMR001522227::cid_44601957 Disintegrin and metalloproteinase domain-containing protein 17 69424 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114132&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44601957 252663648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236414 Cn1c(n[nH]c1=S)-c1sccc1OCc1ccc(Cl)cc1Cl InChI=1S/C14H11Cl2N3OS2/c1-19-13(17-18-14(19)21)12-11(4-5-22-12)20-7-8-2-3-9(15)6-10(8)16/h2-6H,7H2,1H3,(H,18,21) UJJSZCSLQQMCEA-UHFFFAOYSA-N 51989 3-[3-(2,4-dichlorobenzyl)oxy-2-thienyl]-4-methyl-1H-1,2,4-triazole-5-thione::3-[3-[(2,4-dichlorophenyl)methoxy]-2-thiophenyl]-4-methyl-1H-1,2,4-triazole-5-thione::3-[3-[(2,4-dichlorophenyl)methoxy]thiophen-2-yl]-4-methyl-1H-1,2,4-triazole-5-thione::5-{3-[(2,4-dichlorobenzyl)oxy]-2-thienyl}-4-methyl-4H-1,2,4-triazole-3-thiol::MLS000692151::SMR000333829::cid_1482500 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51989&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1482500 252632144 ZINC18208707 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236415 Cc1ccc(cc1)C(=O)N1CCN(CC1)C1C(NS(=O)(=O)c2ccccc2)c2cccc3cccc1c23 InChI=1S/C30H29N3O3S/c1-21-13-15-23(16-14-21)30(34)33-19-17-32(18-20-33)29-26-12-6-8-22-7-5-11-25(27(22)26)28(29)31-37(35,36)24-9-3-2-4-10-24/h2-16,28-29,31H,17-20H2,1H3 OXKSCZRCMSYMHX-UHFFFAOYSA-N 61021 MLS000551367::N-[2-(4-p-toluoylpiperazino)acenaphthen-1-yl]benzenesulfonamide::N-[2-[4-(4-methylbenzoyl)piperazin-1-yl]-1,2-dihydroacenaphthylen-1-yl]benzenesulfonamide::N-[2-[4-(4-methylphenyl)carbonylpiperazin-1-yl]-1,2-dihydroacenaphthylen-1-yl]benzenesulfonamide::N-[2-[4-[(4-methylphenyl)-oxomethyl]-1-piperazinyl]-1,2-dihydroacenaphthylen-1-yl]benzenesulfonamide::N-{2-[4-(4-Methyl-benzoyl)-piperazin-1-yl]-acenaphthen-1-yl}-benzenesulfonamide::SMR000145292::cid_3540854 Disintegrin and metalloproteinase domain-containing protein 17 69508 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=61021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=61021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3540854 252640185 ZINC20029397 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236416 CCOC(=O)CC(SP1(=S)OCC2(CCCCO2)C(O1)C1CCCCO1)C(=O)OCC InChI=1S/C20H33O8PS2/c1-3-23-17(21)13-16(19(22)24-4-2)31-29(30)27-14-20(10-6-8-12-26-20)18(28-29)15-9-5-7-11-25-15/h15-16,18H,3-14H2,1-2H3 MHIPXVSGXGIRHO-UHFFFAOYSA-N 114133 2-[(5-tetrahydropyran-2-yl-3-thioxo-2,4,7-trioxa-3-phosphaspiro[5.5]undecan-3-yl)thio]succinic acid diethyl ester::2-[[5-(2-oxanyl)-3-sulfanylidene-2,4,7-trioxa-3-phosphaspiro[5.5]undecan-3-yl]thio]butanedioic acid diethyl ester::MLS002639327::SMR001548772::cid_232682::diethyl 2-[[5-(oxan-2-yl)-3-sulfanylidene-2,4,7-trioxa-3-phosphaspiro[5.5]undecan-3-yl]sulfanyl]butanedioate Disintegrin and metalloproteinase domain-containing protein 17 32803 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114133&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 232682 252663649 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236417 Cc1ccc(CC2(NC(=O)NC2=O)c2ccccc2)cc1 InChI=1S/C17H16N2O2/c1-12-7-9-13(10-8-12)11-17(14-5-3-2-4-6-14)15(20)18-16(21)19-17/h2-10H,11H2,1H3,(H2,18,19,20,21) QQSBKOAFYCBGFA-UHFFFAOYSA-N 114134 5-(4-methylbenzyl)-5-phenyl-hydantoin::5-[(4-methylphenyl)methyl]-5-phenyl-imidazolidine-2,4-dione::5-[(4-methylphenyl)methyl]-5-phenylimidazolidine-2,4-dione::MLS002667437::SMR001557203::cid_242474 Disintegrin and metalloproteinase domain-containing protein 17 18607 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114134&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 242474 252663650 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236418 Clc1cccc(NC(=O)OCCOCCOC(=O)Nc2cccc(Cl)c2)c1 InChI=1S/C18H18Cl2N2O5/c19-13-3-1-5-15(11-13)21-17(23)26-9-7-25-8-10-27-18(24)22-16-6-2-4-14(20)12-16/h1-6,11-12H,7-10H2,(H,21,23)(H,22,24) JCMRQWGIMATFIT-UHFFFAOYSA-N 114135 2-[2-[(3-chlorophenyl)carbamoyloxy]ethoxy]ethyl N-(3-chlorophenyl)carbamate::MLS002667892::N-(3-chlorophenyl)carbamic acid 2-[2-[(3-chloroanilino)-oxomethoxy]ethoxy]ethyl ester::N-(3-chlorophenyl)carbamic acid 2-[2-[(3-chlorophenyl)carbamoyloxy]ethoxy]ethyl ester::SMR001557649::cid_245556 Disintegrin and metalloproteinase domain-containing protein 17 69433 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114135&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 245556 252663651 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236419 ClCCN(CCCl)c1ccc(C=NNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 InChI=1S/C21H20Cl2N4O2/c22-9-11-27(12-10-23)16-7-5-15(6-8-16)13-25-26-21(29)20(28)18-14-24-19-4-2-1-3-17(18)19/h1-8,13-14,24H,9-12H2,(H,26,29)/b25-13+ HQSZFBZWHLZCCR-DHRITJCHSA-N 88675 MLS002693509::N-[[4-[bis(2-chloroethyl)amino]benzylidene]amino]-2-(1H-indol-3-yl)-2-keto-acetamide::N-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-2-(1H-indol-3-yl)-2-oxidanylidene-ethanamide::N-[[4-[bis(2-chloroethyl)amino]phenyl]methylideneamino]-2-(1H-indol-3-yl)-2-oxoacetamide::SMR001559460::cid_248413 Disintegrin and metalloproteinase domain-containing protein 17 69483 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88675&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 248413 252660314 ZINC73048508 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236420 CC(C)(C)OC(=O)N1CCCC(C1)C(=O)Nc1cccc(c1)C(=O)NCCCCc1ccccc1 InChI=1S/C28H37N3O4/c1-28(2,3)35-27(34)31-18-10-15-23(20-31)26(33)30-24-16-9-14-22(19-24)25(32)29-17-8-7-13-21-11-5-4-6-12-21/h4-6,9,11-12,14,16,19,23H,7-8,10,13,15,17-18,20H2,1-3H3,(H,29,32)(H,30,33) JTUDBUSBDQUUBD-UHFFFAOYSA-N 114136 3-[[3-(4-phenylbutylcarbamoyl)phenyl]carbamoyl]piperidine-1-carboxylic acid tert-butyl ester::3-[oxo-[3-[oxo-(4-phenylbutylamino)methyl]anilino]methyl]-1-piperidinecarboxylic acid tert-butyl ester::MLS002699634::SMR001563542::cid_45280912::tert-butyl 3-[[3-(4-phenylbutylcarbamoyl)phenyl]carbamoyl]piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114136&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45280912 252663652 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236421 CCCn1c(CCNc2nc(cs2)-c2cccc(Br)c2)nc2ccccc12 InChI=1S/C21H21BrN4S/c1-2-12-26-19-9-4-3-8-17(19)24-20(26)10-11-23-21-25-18(14-27-21)15-6-5-7-16(22)13-15/h3-9,13-14H,2,10-12H2,1H3,(H,23,25) RIVNKANIIWBZGA-UHFFFAOYSA-N 114137 4-(3-bromophenyl)-N-(2-(1-propyl-1H-benzo[d]imidazol-2-yl)ethyl)thiazol-2-amine::4-(3-bromophenyl)-N-[2-(1-propyl-2-benzimidazolyl)ethyl]-2-thiazolamine::4-(3-bromophenyl)-N-[2-(1-propylbenzimidazol-2-yl)ethyl]-1,3-thiazol-2-amine::MLS002699875::SMR001563685::[4-(3-bromophenyl)thiazol-2-yl]-[2-(1-propylbenzimidazol-2-yl)ethyl]amine::cid_45280928 Disintegrin and metalloproteinase domain-containing protein 17 69569 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114137&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45280928 252663653 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236422 OC[C@H]1OC(Oc2cccc3[C@@H]([C@@H]4c5cccc(O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)c5C(=O)c5c(O)cc(cc45)C(O)=O)c4cc(cc(O)c4C(=O)c23)C(O)=O)[C@H](O)[C@@H](O)[C@@H]1O InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25-,26-,31-,32-,35+,36+,37-,38-,41-,42?/m1/s1 IPQVTOJGNYVQEO-GTCVFCFLSA-N 53380 MLS001332477::SMR000857110::Sennoside A::cid_16218404 Disintegrin and metalloproteinase domain-containing protein 17 30390 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53380 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53380&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16218404 242053240 C03400 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236423 COc1ccc(Cn2cc(CN3CCS(=O)(=O)N(Cc4ccc(cc4)-c4cccc(Cl)c4)C(C)C3=O)nn2)cc1 InChI=1S/C29H30ClN5O4S/c1-21-29(36)33(19-27-20-34(32-31-27)17-22-8-12-28(39-2)13-9-22)14-15-40(37,38)35(21)18-23-6-10-24(11-7-23)25-4-3-5-26(30)16-25/h3-13,16,20-21H,14-15,17-19H2,1-2H3 VPAHZUSERNKUHK-UHFFFAOYSA-N 114138 2-[4-(3-chlorophenyl)benzyl]-1,1-diketo-3-methyl-5-[(1-p-anisyltriazol-4-yl)methyl]-1,2,5-thiadiazepan-4-one::2-[[4-(3-chlorophenyl)phenyl]methyl]-5-[[1-[(4-methoxyphenyl)methyl]-1,2,3-triazol-4-yl]methyl]-3-methyl-1,1-bis(oxidanylidene)-1,2,5-thiadiazepan-4-one::2-[[4-(3-chlorophenyl)phenyl]methyl]-5-[[1-[(4-methoxyphenyl)methyl]-4-triazolyl]methyl]-3-methyl-1,1-dioxo-1,2,5-thiadiazepan-4-one::2-[[4-(3-chlorophenyl)phenyl]methyl]-5-[[1-[(4-methoxyphenyl)methyl]triazol-4-yl]methyl]-3-methyl-1,1-dioxo-1,2,5-thiadiazepan-4-one::KUC103944::MLS002768199::SMR001788140::cid_45479946 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114138&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45479946 252663654 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236424 COc1ccc(cc1OC)-c1ccc(CN2C(C(C)C)C(=O)N(Cc3cn(Cc4ccco4)nn3)CCS2(=O)=O)cc1 InChI=1S/C30H35N5O6S/c1-21(2)29-30(36)33(18-25-19-34(32-31-25)20-26-6-5-14-41-26)13-15-42(37,38)35(29)17-22-7-9-23(10-8-22)24-11-12-27(39-3)28(16-24)40-4/h5-12,14,16,19,21,29H,13,15,17-18,20H2,1-4H3 SGOKXAFHUGKLKV-UHFFFAOYSA-N 114139 2-[4-(3,4-dimethoxyphenyl)benzyl]-5-[[1-(2-furfuryl)triazol-4-yl]methyl]-3-isopropyl-1,1-diketo-1,2,5-thiadiazepan-4-one::2-[[4-(3,4-dimethoxyphenyl)phenyl]methyl]-5-[[1-(2-furanylmethyl)-4-triazolyl]methyl]-1,1-dioxo-3-propan-2-yl-1,2,5-thiadiazepan-4-one::2-[[4-(3,4-dimethoxyphenyl)phenyl]methyl]-5-[[1-(furan-2-ylmethyl)-1,2,3-triazol-4-yl]methyl]-1,1-bis(oxidanylidene)-3-propan-2-yl-1,2,5-thiadiazepan-4-one::2-[[4-(3,4-dimethoxyphenyl)phenyl]methyl]-5-[[1-(furan-2-ylmethyl)triazol-4-yl]methyl]-1,1-dioxo-3-propan-2-yl-1,2,5-thiadiazepan-4-one::KUC104878::MLS003116357::SMR001831910::cid_46903111 Disintegrin and metalloproteinase domain-containing protein 17 69497 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114139&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46903111 252663655 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236425 CCN(Cc1cccc(Br)c1)c1c(CC)nc2ccc(cn12)C(=O)Nc1ccc2NC(=O)COc2c1 InChI=1S/C27H26BrN5O3/c1-3-21-27(32(4-2)14-17-6-5-7-19(28)12-17)33-15-18(8-11-24(33)30-21)26(35)29-20-9-10-22-23(13-20)36-16-25(34)31-22/h5-13,15H,3-4,14,16H2,1-2H3,(H,29,35)(H,31,34) LNOONYYMKWMXCL-UHFFFAOYSA-N 114140 3-[(3-bromobenzyl)-ethyl-amino]-2-ethyl-N-(3-keto-4H-1,4-benzoxazin-7-yl)imidazo[1,2-a]pyridine-6-carboxamide::3-[(3-bromophenyl)methyl-ethyl-amino]-2-ethyl-N-(3-oxidanylidene-4H-1,4-benzoxazin-7-yl)imidazo[1,2-a]pyridine-6-carboxamide::3-[(3-bromophenyl)methyl-ethylamino]-2-ethyl-N-(3-oxo-4H-1,4-benzoxazin-7-yl)-6-imidazo[1,2-a]pyridinecarboxamide::3-[(3-bromophenyl)methyl-ethylamino]-2-ethyl-N-(3-oxo-4H-1,4-benzoxazin-7-yl)imidazo[1,2-a]pyridine-6-carboxamide::MLS003121316::SMR001283912::cid_46942623 Disintegrin and metalloproteinase domain-containing protein 17 69456 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114140&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46942623 252663656 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236426 COc1cccc(c1)C(NC(C)=O)c1nc(cs1)-c1ccc2ccccc2c1 InChI=1S/C23H20N2O2S/c1-15(26)24-22(19-8-5-9-20(13-19)27-2)23-25-21(14-28-23)18-11-10-16-6-3-4-7-17(16)12-18/h3-14,22H,1-2H3,(H,24,26) RCSKGZIKKZDKNK-UHFFFAOYSA-N 114141 MLS003122441::N-[(3-methoxyphenyl)-(4-naphthalen-2-yl-1,3-thiazol-2-yl)methyl]acetamide::N-[(3-methoxyphenyl)-(4-naphthalen-2-yl-1,3-thiazol-2-yl)methyl]ethanamide::N-[(3-methoxyphenyl)-[4-(2-naphthalenyl)-2-thiazolyl]methyl]acetamide::N-[(3-methoxyphenyl)-[4-(2-naphthyl)thiazol-2-yl]methyl]acetamide::SMR001277337::cid_46943118 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114141&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46943118 252663657 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236427 OC(c1nc(cs1)-c1cccc(c1)C(F)(F)F)c1ccc(F)c(F)c1 InChI=1S/C17H10F5NOS/c18-12-5-4-10(7-13(12)19)15(24)16-23-14(8-25-16)9-2-1-3-11(6-9)17(20,21)22/h1-8,15,24H IXCZDEBCUXWWMQ-UHFFFAOYSA-N 114142 (3,4-difluorophenyl)-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methanol::(3,4-difluorophenyl)-[4-[3-(trifluoromethyl)phenyl]-2-thiazolyl]methanol::(3,4-difluorophenyl)-[4-[3-(trifluoromethyl)phenyl]thiazol-2-yl]methanol::MLS003122713::SMR001277664::[3,4-bis(fluoranyl)phenyl]-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methanol::cid_46943701 Disintegrin and metalloproteinase domain-containing protein 17 50522 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114142&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46943701 252663658 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236428 CC(C)c1cccc(c1)-c1csc(n1)C(O)c1cccc(Cl)c1 InChI=1S/C19H18ClNOS/c1-12(2)13-5-3-6-14(9-13)17-11-23-19(21-17)18(22)15-7-4-8-16(20)10-15/h3-12,18,22H,1-2H3 XMXOOKCCXKRQNL-UHFFFAOYSA-N 114143 (3-chlorophenyl)-(4-m-cumenylthiazol-2-yl)methanol::(3-chlorophenyl)-[4-(3-propan-2-ylphenyl)-1,3-thiazol-2-yl]methanol::(3-chlorophenyl)-[4-(3-propan-2-ylphenyl)-2-thiazolyl]methanol::MLS003122474::SMR001277378::cid_46948341 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114143&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46948341 252663659 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236429 O=C(Nc1cccc(c1)C#N)c1cc(on1)C1CCCCN1S(=O)(=O)c1ccccc1 InChI=1S/C22H20N4O4S/c23-15-16-7-6-8-17(13-16)24-22(27)19-14-21(30-25-19)20-11-4-5-12-26(20)31(28,29)18-9-2-1-3-10-18/h1-3,6-10,13-14,20H,4-5,11-12H2,(H,24,27) NIBYYSMIWRWRJF-UHFFFAOYSA-N 114144 5-(1-besyl-2-piperidyl)-N-(3-cyanophenyl)isoxazole-3-carboxamide::5-[1-(benzenesulfonyl)-2-piperidinyl]-N-(3-cyanophenyl)-3-isoxazolecarboxamide::5-[1-(benzenesulfonyl)piperidin-2-yl]-N-(3-cyanophenyl)-1,2-oxazole-3-carboxamide::MLS003119759::N-(3-cyanophenyl)-5-[1-(phenylsulfonyl)piperidin-2-yl]-1,2-oxazole-3-carboxamide::SMR001275816::cid_49778479 Disintegrin and metalloproteinase domain-containing protein 17 69484 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114144&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49778479 252663660 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236430 COc1ccc(NC(=O)C2(C)Cc3c(O2)nccc3-c2cccc(c2)C(F)(F)F)cn1 InChI=1S/C22H18F3N3O3/c1-21(20(29)28-15-6-7-18(30-2)27-12-15)11-17-16(8-9-26-19(17)31-21)13-4-3-5-14(10-13)22(23,24)25/h3-10,12H,11H2,1-2H3,(H,28,29) IIHNYQXFLQRCAS-UHFFFAOYSA-N 114145 MLS003120444::N-(6-methoxy-3-pyridinyl)-2-methyl-4-[3-(trifluoromethyl)phenyl]-3H-furo[2,3-b]pyridine-2-carboxamide::N-(6-methoxy-3-pyridyl)-2-methyl-4-[3-(trifluoromethyl)phenyl]-3H-furo[2,3-b]pyridine-2-carboxamide::N-(6-methoxypyridin-3-yl)-2-methyl-4-[3-(trifluoromethyl)phenyl]-3H-furo[2,3-b]pyridine-2-carboxamide::SMR001289763::cid_49789320 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114145&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49789320 252663661 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236431 COc1ccc(cc1)-c1cnc(N)nc1-c1ccc(OCC(C)=C)cc1O InChI=1S/C21H21N3O3/c1-13(2)12-27-16-8-9-17(19(25)10-16)20-18(11-23-21(22)24-20)14-4-6-15(26-3)7-5-14/h4-11,25H,1,12H2,2-3H3,(H2,22,23,24) APRGBLOXXLPHPL-UHFFFAOYSA-N 42653 (6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-(2-methylallyloxy)cyclohexa-2,4-dien-1-one::(6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-(2-methylprop-2-enoxy)-1-cyclohexa-2,4-dienone::(6E)-6-[2-amino-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-(2-methylprop-2-enoxy)cyclohexa-2,4-dien-1-one::(6E)-6-[2-azanyl-5-(4-methoxyphenyl)-1H-pyrimidin-6-ylidene]-3-(2-methylprop-2-enoxy)cyclohexa-2,4-dien-1-one::MLS000083257::SMR000046524::cid_5389930 Disintegrin and metalloproteinase domain-containing protein 17 69492 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42653&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5389930 252623345 ZINC13127203 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236432 CCc1nc2ccc(cn2c1N(C)Cc1nccs1)C(=O)Nc1cc(ccc1OC)-c1ccccc1 InChI=1S/C28H27N5O2S/c1-4-22-28(32(2)18-26-29-14-15-36-26)33-17-21(11-13-25(33)30-22)27(34)31-23-16-20(10-12-24(23)35-3)19-8-6-5-7-9-19/h5-17H,4,18H2,1-3H3,(H,31,34) VJWIXMHAXKDHRC-UHFFFAOYSA-N 114146 2-ethyl-N-(2-methoxy-5-phenyl-phenyl)-3-[methyl(1,3-thiazol-2-ylmethyl)amino]imidazo[1,2-a]pyridine-6-carboxamide::2-ethyl-N-(2-methoxy-5-phenyl-phenyl)-3-[methyl(thiazol-2-ylmethyl)amino]imidazo[1,2-a]pyridine-6-carboxamide::2-ethyl-N-(2-methoxy-5-phenylphenyl)-3-[methyl(1,3-thiazol-2-ylmethyl)amino]imidazo[1,2-a]pyridine-6-carboxamide::2-ethyl-N-(2-methoxy-5-phenylphenyl)-3-[methyl(2-thiazolylmethyl)amino]-6-imidazo[1,2-a]pyridinecarboxamide::MLS003121217::SMR001283578::cid_49791456 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114146&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49791456 252663662 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236433 Cc1ccc(cc1)S(=O)(=O)N1C[C@@H]2[C@H](C[C@H]1c1cccc3ccccc13)N([C@@H](CC2=O)c1ccccc1)S(=O)(=O)c1ccc(C)cc1 InChI=1S/C38H36N2O5S2/c1-26-15-19-30(20-16-26)46(42,43)39-25-34-37(23-36(39)33-14-8-12-28-9-6-7-13-32(28)33)40(47(44,45)31-21-17-27(2)18-22-31)35(24-38(34)41)29-10-4-3-5-11-29/h3-22,34-37H,23-25H2,1-2H3/t34-,35+,36+,37+/m1/s1 VWZBEAVDWBUHHT-HQPLKVBUSA-N 114147 (2S,4aR,7S,8aS)-1,6-bis-(4-methylphenyl)sulfonyl-7-(1-naphthalenyl)-2-phenyl-3,4a,5,7,8,8a-hexahydro-2H-1,6-naphthyridin-4-one::(2S,4aR,7S,8aS)-1,6-bis-(4-methylphenyl)sulfonyl-7-naphthalen-1-yl-2-phenyl-3,4a,5,7,8,8a-hexahydro-2H-1,6-naphthyridin-4-one::(2S,4aR,7S,8aS)-7-(1-naphthyl)-2-phenyl-1,6-ditosyl-3,4a,5,7,8,8a-hexahydro-2H-1,6-naphthyridin-4-one::MLS003178988::SMR001882782::cid_51359294 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114147&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51359294 252663663 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236434 CCOC(=O)\C=C1/CN(Cc2ccc(OC)cc2)S(=O)(=O)c2ccccc12 InChI=1S/C20H21NO5S/c1-3-26-20(22)12-16-14-21(13-15-8-10-17(25-2)11-9-15)27(23,24)19-7-5-4-6-18(16)19/h4-12H,3,13-14H2,1-2H3/b16-12+ RYQDPHUGUGSNLQ-FOWTUZBSSA-N 114148 (2Z)-2-(1,1-diketo-2-p-anisyl-3H-1,2-benzothiazin-4-ylidene)acetic acid ethyl ester::(2Z)-2-[2-[(4-methoxyphenyl)methyl]-1,1-dioxo-3H-1,2-benzothiazin-4-ylidene]acetic acid ethyl ester::MLS003172046::SMR000674029::cid_24819129::ethyl (2Z)-2-[2-[(4-methoxyphenyl)methyl]-1,1-bis(oxidanylidene)-3H-1,2-benzothiazin-4-ylidene]ethanoate::ethyl (2Z)-2-[2-[(4-methoxyphenyl)methyl]-1,1-dioxo-3H-1,2-benzothiazin-4-ylidene]acetate Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114148&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24819129 252663664 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236435 COc1ccc(cc1)C(N1CCN(C\C=C\c2ccccc2)CC1)c1nnnn1Cc1ccccc1 InChI=1S/C29H32N6O/c1-36-27-16-14-26(15-17-27)28(29-30-31-32-35(29)23-25-11-6-3-7-12-25)34-21-19-33(20-22-34)18-8-13-24-9-4-2-5-10-24/h2-17,28H,18-23H2,1H3/b13-8+ GEXONMIUVXRBLQ-MDWZMJQESA-N 114149 1-[(1-benzyltetrazol-5-yl)-(4-methoxyphenyl)methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine::1-[(1-benzyltetrazol-5-yl)-(4-methoxyphenyl)methyl]-4-[(E)-cinnamyl]piperazine::1-[(4-methoxyphenyl)-[1-(phenylmethyl)-1,2,3,4-tetrazol-5-yl]methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine::1-[(4-methoxyphenyl)-[1-(phenylmethyl)-5-tetrazolyl]methyl]-4-[(E)-3-phenylprop-2-enyl]piperazine::MLS003315759::SMR001994894::cid_51360416 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114149&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51360416 252663665 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236436 CCC(N1CCC2(CC1)N(CNC2=O)c1ccccc1)c1nnnn1Cc1ccccc1 InChI=1S/C24H29N7O/c1-2-21(22-26-27-28-31(22)17-19-9-5-3-6-10-19)29-15-13-24(14-16-29)23(32)25-18-30(24)20-11-7-4-8-12-20/h3-12,21H,2,13-18H2,1H3,(H,25,32) MBROEKYLYYCEBX-UHFFFAOYSA-N 114150 1-phenyl-8-[1-[1-(phenylmethyl)-1,2,3,4-tetrazol-5-yl]propyl]-1,3,8-triazaspiro[4.5]decan-4-one::1-phenyl-8-[1-[1-(phenylmethyl)-5-tetrazolyl]propyl]-1,3,8-triazaspiro[4.5]decan-4-one::8-[1-(1-benzyltetrazol-5-yl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::MLS003265707::SMR001941250::cid_51360812 Disintegrin and metalloproteinase domain-containing protein 17 69438 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114150&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51360812 252663666 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236437 CC(C)(C)S(=O)N1Cc2cc(nc(c2[C@H]1CCO)-c1cccc(c1)-c1cccc(F)c1)C(=O)NCC(F)(F)F InChI=1S/C28H29F4N3O3S/c1-27(2,3)39(38)35-15-20-14-22(26(37)33-16-28(30,31)32)34-25(24(20)23(35)10-11-36)19-8-4-6-17(12-19)18-7-5-9-21(29)13-18/h4-9,12-14,23,36H,10-11,15-16H2,1-3H3,(H,33,37)/t23-,39?/m1/s1 WZDAFVZLMKVKDS-YBXHNAATSA-N 114151 (3R)-2-tert-butylsulfinyl-4-[3-(3-fluorophenyl)phenyl]-3-(2-hydroxyethyl)-N-(2,2,2-trifluoroethyl)-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide::(3R)-2-tert-butylsulfinyl-4-[3-(3-fluorophenyl)phenyl]-3-(2-hydroxyethyl)-N-[2,2,2-tris(fluoranyl)ethyl]-1,3-dihydropyrrolo[3,4-c]pyridine-6-carboxamide::MLS003367994::SMR002044499::cid_51361581 Disintegrin and metalloproteinase domain-containing protein 17 69485 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114151&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51361581 252663667 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236438 Cc1ccc(cc1)S(=O)(=O)N1CCN([C@H](COC(=O)Nc2ccccc2)Cc2ccccc2)C(=O)CC1 InChI=1S/C28H31N3O5S/c1-22-12-14-26(15-13-22)37(34,35)30-17-16-27(32)31(19-18-30)25(20-23-8-4-2-5-9-23)21-36-28(33)29-24-10-6-3-7-11-24/h2-15,25H,16-21H2,1H3,(H,29,33)/t25-/m0/s1 VXSDZUHINATVIK-VWLOTQADSA-N 114152 MLS003512359::N-phenylcarbamic acid [(2S)-2-(7-keto-4-tosyl-1,4-diazepan-1-yl)-3-phenyl-propyl] ester::N-phenylcarbamic acid [(2S)-2-[4-(4-methylphenyl)sulfonyl-7-oxo-1,4-diazepan-1-yl]-3-phenylpropyl] ester::SMR002164220::[(2S)-2-[4-(4-methylphenyl)sulfonyl-7-oxidanylidene-1,4-diazepan-1-yl]-3-phenyl-propyl] N-phenylcarbamate::[(2S)-2-[4-(4-methylphenyl)sulfonyl-7-oxo-1,4-diazepan-1-yl]-3-phenylpropyl] N-phenylcarbamate::cid_25010880 Disintegrin and metalloproteinase domain-containing protein 17 69448 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114152&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25010880 252663668 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236439 C[C@@H](N1C[C@H](COCc2ccccc2)Oc2cc(ccc2S1(=O)=O)N1CC[C@@H](O)C1)c1ccccc1 InChI=1S/C28H32N2O5S/c1-21(23-10-6-3-7-11-23)30-18-26(20-34-19-22-8-4-2-5-9-22)35-27-16-24(29-15-14-25(31)17-29)12-13-28(27)36(30,32)33/h2-13,16,21,25-26,31H,14-15,17-20H2,1H3/t21-,25-,26-/m1/s1 ZVFLCRXQLXNXFG-LPPUWEFUSA-N 114153 (3R)-1-[(4R)-1,1-bis(oxidanylidene)-2-[(1R)-1-phenylethyl]-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::(3R)-1-[(4R)-1,1-dioxo-2-[(1R)-1-phenylethyl]-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]-3-pyrrolidinol::(3R)-1-[(4R)-1,1-dioxo-2-[(1R)-1-phenylethyl]-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::(3R)-1-[(4R)-4-(benzoxymethyl)-1,1-diketo-2-[(1R)-1-phenylethyl]-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::MLS003591791::SMR002253087::cid_53301556 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114153&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53301556 252663669 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236440 CCCCC[C@@H](C)N1C[C@@H](COCc2ccccc2)Oc2cc(ccc2S1(=O)=O)N1CCC[C@H]1CO InChI=1S/C28H40N2O5S/c1-3-4-6-10-22(2)30-18-26(21-34-20-23-11-7-5-8-12-23)35-27-17-24(14-15-28(27)36(30,32)33)29-16-9-13-25(29)19-31/h5,7-8,11-12,14-15,17,22,25-26,31H,3-4,6,9-10,13,16,18-21H2,1-2H3/t22-,25+,26+/m1/s1 RKYZJKLNTURKTQ-RZFJZAQRSA-N 114154 MLS003591820::SMR002253116::[(2S)-1-[(4S)-2-[(2R)-heptan-2-yl]-1,1-bis(oxidanylidene)-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-2-yl]methanol::[(2S)-1-[(4S)-2-[(2R)-heptan-2-yl]-1,1-dioxo-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]-2-pyrrolidinyl]methanol::[(2S)-1-[(4S)-2-[(2R)-heptan-2-yl]-1,1-dioxo-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-2-yl]methanol::[(2S)-1-[(4S)-4-(benzoxymethyl)-1,1-diketo-2-[(1R)-1-methylhexyl]-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-2-yl]methanol::cid_53301585 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114154&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53301585 252663670 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236441 COc1cccc(c1)C(Nc1ccccc1)c1ccc2ccc(C)nc2c1O InChI=1S/C24H22N2O2/c1-16-11-12-17-13-14-21(24(27)23(17)25-16)22(26-19-8-4-3-5-9-19)18-7-6-10-20(15-18)28-2/h3-15,22,26-27H,1-2H3 MDOZEKOSAHOQPL-UHFFFAOYSA-N 114155 7-((3-methoxyphenyl)(phenylamino)methyl)-2-methylquinolin-8-ol::7-[(3-methoxyphenyl)-phenylazanyl-methyl]-2-methyl-quinolin-8-ol;2,2,2-tris(fluoranyl)ethanoic acid::7-[anilino-(3-methoxyphenyl)methyl]-2-methyl-8-quinolinol;2,2,2-trifluoroacetic acid::7-[anilino-(3-methoxyphenyl)methyl]-2-methyl-quinolin-8-ol;2,2,2-trifluoroacetic acid::7-[anilino-(3-methoxyphenyl)methyl]-2-methylquinolin-8-ol;2,2,2-trifluoroacetic acid::MLS003675381::SMR002355991::cid_53383533 Disintegrin and metalloproteinase domain-containing protein 17 69217 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114155&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53312377 252663671 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236442 Nc1[nH]c(C(=O)c2ccc(Br)cc2)c(c1C(=O)NCCc1c[nH]c2ccccc12)-c1ccccn1 InChI=1S/C27H22BrN5O2/c28-18-10-8-16(9-11-18)25(34)24-22(21-7-3-4-13-30-21)23(26(29)33-24)27(35)31-14-12-17-15-32-20-6-2-1-5-19(17)20/h1-11,13,15,32-33H,12,14,29H2,(H,31,35) WOPLFGSURRTEMY-UHFFFAOYSA-N 114156 2-amino-5-(4-bromobenzoyl)-N-[2-(1H-indol-3-yl)ethyl]-4-(2-pyridyl)-1H-pyrrole-3-carboxamide::2-amino-5-(4-bromobenzoyl)-N-[2-(1H-indol-3-yl)ethyl]-4-pyridin-2-yl-1H-pyrrole-3-carboxamide::2-amino-5-[(4-bromophenyl)-oxomethyl]-N-[2-(1H-indol-3-yl)ethyl]-4-(2-pyridinyl)-1H-pyrrole-3-carboxamide::2-azanyl-5-(4-bromophenyl)carbonyl-N-[2-(1H-indol-3-yl)ethyl]-4-pyridin-2-yl-1H-pyrrole-3-carboxamide::MLS003826344::N-(2-(1H-indol-3-yl)ethyl)-2-amino-5-(4-bromobenzoyl)-4-(pyridin-2-yl)-1H-pyrrole-3-carboxamide::SMR002504550::cid_56588222 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114156&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56588222 252663672 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236443 Nc1[nH]c(C(=O)c2ccc(Br)cc2)c(c1C(=O)NCCc1c[nH]c2ccccc12)-c1ccc(Cl)cc1[N+]([O-])=O InChI=1S/C28H21BrClN5O4/c29-17-7-5-15(6-8-17)26(36)25-23(20-10-9-18(30)13-22(20)35(38)39)24(27(31)34-25)28(37)32-12-11-16-14-33-21-4-2-1-3-19(16)21/h1-10,13-14,33-34H,11-12,31H2,(H,32,37) NSYILTRFSNGQMA-UHFFFAOYSA-N 114157 2-amino-5-(4-bromobenzoyl)-4-(4-chloro-2-nitro-phenyl)-N-[2-(1H-indol-3-yl)ethyl]-1H-pyrrole-3-carboxamide::2-amino-5-(4-bromobenzoyl)-4-(4-chloro-2-nitrophenyl)-N-[2-(1H-indol-3-yl)ethyl]-1H-pyrrole-3-carboxamide::2-amino-5-[(4-bromophenyl)-oxomethyl]-4-(4-chloro-2-nitrophenyl)-N-[2-(1H-indol-3-yl)ethyl]-1H-pyrrole-3-carboxamide::2-azanyl-5-(4-bromophenyl)carbonyl-4-(4-chloranyl-2-nitro-phenyl)-N-[2-(1H-indol-3-yl)ethyl]-1H-pyrrole-3-carboxamide::MLS003826391::N-(2-(1H-indol-3-yl)ethyl)-2-amino-5-(4-bromobenzoyl)-4-(4-chloro-2-nitrophenyl)-1H-pyrrole-3-carboxamide::SMR002504577::cid_56588248 Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114157&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56588248 252663673 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236444 COC(=O)C1=C(C)N(Cc2ccc(Br)cc2)C(=S)NC1c1ccc(F)cc1 InChI=1S/C20H18BrFN2O2S/c1-12-17(19(25)26-2)18(14-5-9-16(22)10-6-14)23-20(27)24(12)11-13-3-7-15(21)8-4-13/h3-10,18H,11H2,1-2H3,(H,23,27) QNAYAPDCGCYMEK-UHFFFAOYSA-N 114158 3-(4-bromobenzyl)-6-(4-fluorophenyl)-4-methyl-2-thioxo-1,6-dihydropyrimidine-5-carboxylic acid methyl ester::3-[(4-bromophenyl)methyl]-6-(4-fluorophenyl)-4-methyl-2-sulfanylidene-1,6-dihydropyrimidine-5-carboxylic acid methyl ester::MLS003843119::SMR002515832::cid_56588748::methyl 3-[(4-bromophenyl)methyl]-6-(4-fluorophenyl)-4-methyl-2-sulfanylidene-1,6-dihydropyrimidine-5-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69583 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114158&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56588748 252663674 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236445 COC(=O)C1=C(C)N(Cc2cccc(c2)C(F)(F)F)C(NCc2ccc3OCOc3c2)=NC1c1ccc(F)cc1 InChI=1S/C29H25F4N3O4/c1-17-25(27(37)38-2)26(20-7-9-22(30)10-8-20)35-28(34-14-18-6-11-23-24(13-18)40-16-39-23)36(17)15-19-4-3-5-21(12-19)29(31,32)33/h3-13,26H,14-16H2,1-2H3,(H,34,35) LGKYJECCBHCOIR-UHFFFAOYSA-N 114159 2-(1,3-benzodioxol-5-ylmethylamino)-4-(4-fluorophenyl)-6-methyl-1-[[3-(trifluoromethyl)phenyl]methyl]-4H-pyrimidine-5-carboxylic acid methyl ester::4-(4-fluorophenyl)-6-methyl-2-(piperonylamino)-1-[3-(trifluoromethyl)benzyl]-4H-pyrimidine-5-carboxylic acid methyl ester::MLS003843192::SMR002515905::cid_53316051::methyl 2-(1,3-benzodioxol-5-ylmethylamino)-4-(4-fluorophenyl)-6-methyl-1-[[3-(trifluoromethyl)phenyl]methyl]-4H-pyrimidine-5-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114159&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53316051 252663675 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236446 CCOC(=O)C1=C(C2N(Cc3ccc(cc3)C#N)c3ccccc3[C@@]22C[C@H](N(C2=N1)S(=O)(=O)c1ccc(OC)cc1)C(=O)OC)C(=O)OCC InChI=1S/C36H34N4O9S/c1-5-48-33(42)29-30(34(43)49-6-2)38-35-36(19-28(32(41)47-4)40(35)50(44,45)25-17-15-24(46-3)16-18-25)26-9-7-8-10-27(26)39(31(29)36)21-23-13-11-22(20-37)12-14-23/h7-18,28,31H,5-6,19,21H2,1-4H3/t28-,31?,36-/m0/s1 MCHYUAOGLMZCKA-SUPQIXAGSA-N 114160 MLS003843288::SMR002516001::cid_53315937 Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114160&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53315937 242053894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236447 Clc1ccc(cc1)-n1c(COc2ccccc2)nnc1SCC(=O)Nc1ccccc1-c1ccccc1 InChI=1S/C29H23ClN4O2S/c30-22-15-17-23(18-16-22)34-27(19-36-24-11-5-2-6-12-24)32-33-29(34)37-20-28(35)31-26-14-8-7-13-25(26)21-9-3-1-4-10-21/h1-18H,19-20H2,(H,31,35) ZUNFEHSUKKFQNU-UHFFFAOYSA-N 114161 2-[[4-(4-chlorophenyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-phenylphenyl)acetamide::2-[[4-(4-chlorophenyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-phenylphenyl)ethanamide::2-[[4-(4-chlorophenyl)-5-(phenoxymethyl)-1,2,4-triazol-3-yl]thio]-N-(2-phenylphenyl)acetamide::MLS003127825::SMR001835887::cid_2038103 Disintegrin and metalloproteinase domain-containing protein 17 69478 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114161&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2038103 252663676 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236448 Cc1ccc(OCc2nnc(SC\C=C\c3ccccc3)n2Cc2ccco2)cc1 InChI=1S/C24H23N3O2S/c1-19-11-13-21(14-12-19)29-18-23-25-26-24(27(23)17-22-10-5-15-28-22)30-16-6-9-20-7-3-2-4-8-20/h2-15H,16-18H2,1H3/b9-6+ VPJWEJDVRAHKAH-RMKNXTFCSA-N 114162 3-[[(E)-cinnamyl]thio]-4-(2-furfuryl)-5-[(4-methylphenoxy)methyl]-1,2,4-triazole::4-(2-furanylmethyl)-3-[(4-methylphenoxy)methyl]-5-[[(E)-3-phenylprop-2-enyl]thio]-1,2,4-triazole::4-(furan-2-ylmethyl)-3-[(4-methylphenoxy)methyl]-5-[(E)-3-phenylprop-2-enyl]sulfanyl-1,2,4-triazole::MLS003127856::SMR001835918::cid_5961704 Disintegrin and metalloproteinase domain-containing protein 17 69562 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114162&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5961704 252663677 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236449 C(Sc1nnc(-c2ccccn2)n1-c1ccccc1)c1cccc2ccccc12 InChI=1S/C24H18N4S/c1-2-12-20(13-3-1)28-23(22-15-6-7-16-25-22)26-27-24(28)29-17-19-11-8-10-18-9-4-5-14-21(18)19/h1-16H,17H2 OCBOOXALSZKYSZ-UHFFFAOYSA-N 114163 2-[5-(1-naphthalenylmethylthio)-4-phenyl-1,2,4-triazol-3-yl]pyridine::2-[5-(1-naphthylmethylthio)-4-phenyl-1,2,4-triazol-3-yl]pyridine::2-[5-(naphthalen-1-ylmethylsulfanyl)-4-phenyl-1,2,4-triazol-3-yl]pyridine::MLS003127929::SMR001835991::cid_1961147 Disintegrin and metalloproteinase domain-containing protein 17 69406 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114163&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1961147 252663678 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236450 CCOc1ccc(cc1)-n1c(SCC(=O)Nc2cc(C)c(NC(=O)c3ccccc3)cc2OC)nnc1-c1cccs1 InChI=1S/C31H29N5O4S2/c1-4-40-23-14-12-22(13-15-23)36-29(27-11-8-16-41-27)34-35-31(36)42-19-28(37)32-25-17-20(2)24(18-26(25)39-3)33-30(38)21-9-6-5-7-10-21/h5-18H,4,19H2,1-3H3,(H,32,37)(H,33,38) DJFJHODONZSSCL-UHFFFAOYSA-N 114164 MLS003127997::N-[4-[2-[[4-(4-ethoxyphenyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]ethanoylamino]-5-methoxy-2-methyl-phenyl]benzamide::N-[4-[[2-[[4-(4-ethoxyphenyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]-5-methoxy-2-methylphenyl]benzamide::N-[4-[[2-[[4-(4-ethoxyphenyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]-5-methoxy-2-methylphenyl]benzamide::N-[5-methoxy-2-methyl-4-[[2-[[4-p-phenetyl-5-(2-thienyl)-1,2,4-triazol-3-yl]thio]acetyl]amino]phenyl]benzamide::SMR001836059::cid_24210558 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114164&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24210558 252663679 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236451 Cc1cccc(NC(=O)CSc2nnc(SCc3ccc(Cl)cc3)s2)c1 InChI=1S/C18H16ClN3OS3/c1-12-3-2-4-15(9-12)20-16(23)11-25-18-22-21-17(26-18)24-10-13-5-7-14(19)8-6-13/h2-9H,10-11H2,1H3,(H,20,23) CUZSKGYBGSHMEG-UHFFFAOYSA-N 114165 2-[[5-[(4-chlorobenzyl)thio]-1,3,4-thiadiazol-2-yl]thio]-N-(m-tolyl)acetamide::2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(3-methylphenyl)acetamide::2-[[5-[(4-chlorophenyl)methylsulfanyl]-1,3,4-thiadiazol-2-yl]sulfanyl]-N-(3-methylphenyl)ethanamide::2-[[5-[(4-chlorophenyl)methylthio]-1,3,4-thiadiazol-2-yl]thio]-N-(3-methylphenyl)acetamide::MLS003128045::SMR001836105::cid_1543070 Disintegrin and metalloproteinase domain-containing protein 17 69448 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114165&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1543070 252663680 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236452 Cc1ccc(cc1C)-c1cc([nH]n1)C(=O)NN=Cc1cccc(OCc2ccccc2)c1 InChI=1S/C26H24N4O2/c1-18-11-12-22(13-19(18)2)24-15-25(29-28-24)26(31)30-27-16-21-9-6-10-23(14-21)32-17-20-7-4-3-5-8-20/h3-16H,17H2,1-2H3,(H,28,29)(H,30,31) QWBOSFHRRAGQHH-UHFFFAOYSA-N 114166 3-(3,4-dimethylphenyl)-N-[(3-phenylmethoxyphenyl)methylideneamino]-1H-pyrazole-5-carboxamide::MLS003128176::N-[(3-benzoxybenzylidene)amino]-3-(3,4-dimethylphenyl)-1H-pyrazole-5-carboxamide::SMR001836228::cid_2046220 Disintegrin and metalloproteinase domain-containing protein 17 69483 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114166&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6891223 252663681 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236453 CC(=NNC(=O)CSc1nnc(-c2ccc(cc2)C(C)(C)C)n1-c1ccccc1)c1cccc2ccccc12 InChI=1S/C32H31N5OS/c1-22(27-16-10-12-23-11-8-9-15-28(23)27)33-34-29(38)21-39-31-36-35-30(37(31)26-13-6-5-7-14-26)24-17-19-25(20-18-24)32(2,3)4/h5-20H,21H2,1-4H3,(H,34,38) GXYKUBCLNXLDAO-UHFFFAOYSA-N 113983 2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-(1-naphthalen-1-ylethylideneamino)acetamide::2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-(1-naphthalen-1-ylethylideneamino)ethanamide::2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]thio]-N-[1-(1-naphthalenyl)ethylideneamino]acetamide::2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]thio]-N-[1-(1-naphthyl)ethylideneamino]acetamide::MLS003128325::SMR001836369::cid_4366183 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113983&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9659437 252663506 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236454 O=C(CSc1nc2ccccc2o1)NN=C\C=C\c1ccccc1 InChI=1S/C18H15N3O2S/c22-17(21-19-12-6-9-14-7-2-1-3-8-14)13-24-18-20-15-10-4-5-11-16(15)23-18/h1-12H,13H2,(H,21,22)/b9-6+,19-12? PZGJVCPKOLRRJG-ZCHOPRNZSA-N 114167 2-(1,3-benzoxazol-2-ylsulfanyl)-N-[[(E)-3-phenylprop-2-enylidene]amino]acetamide::2-(1,3-benzoxazol-2-ylsulfanyl)-N-[[(E)-3-phenylprop-2-enylidene]amino]ethanamide::2-(1,3-benzoxazol-2-ylthio)-N-[[(E)-3-phenylprop-2-enylidene]amino]acetamide::MLS003128366::SMR001836409::cid_57404183 Disintegrin and metalloproteinase domain-containing protein 17 69508 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114167&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 57404183 252663682 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236455 Cc1sc2nc(SCC(=O)c3ccc(O)c(O)c3)n(Cc3ccco3)c(=O)c2c1C InChI=1S/C21H18N2O5S2/c1-11-12(2)30-19-18(11)20(27)23(9-14-4-3-7-28-14)21(22-19)29-10-17(26)13-5-6-15(24)16(25)8-13/h3-8,24-25H,9-10H2,1-2H3 OAJMFGDHCKSVCO-UHFFFAOYSA-N 114168 2-[2-(3,4-dihydroxyphenyl)-2-oxoethyl]sulfanyl-3-(furan-2-ylmethyl)-5,6-dimethylthieno[2,3-d]pyrimidin-4-one::2-[2-[3,4-bis(oxidanyl)phenyl]-2-oxidanylidene-ethyl]sulfanyl-3-(furan-2-ylmethyl)-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-one::2-[[2-(3,4-dihydroxyphenyl)-2-keto-ethyl]thio]-3-(2-furfuryl)-5,6-dimethyl-thieno[2,3-d]pyrimidin-4-one::2-[[2-(3,4-dihydroxyphenyl)-2-oxoethyl]thio]-3-(2-furanylmethyl)-5,6-dimethyl-4-thieno[2,3-d]pyrimidinone::MLS003127620::SMR001835684::cid_24209920 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114168&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24209920 252663683 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236456 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 11.47 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236457 Cc1cc(N2CCN(CC2)C(=O)Oc2ccc(cn2)-c2ccccc2)c2ccccc2n1 InChI=1S/C26H24N4O2/c1-19-17-24(22-9-5-6-10-23(22)28-19)29-13-15-30(16-14-29)26(31)32-25-12-11-21(18-27-25)20-7-3-2-4-8-20/h2-12,17-18H,13-16H2,1H3 UJAPZGDOBGLQJC-UHFFFAOYSA-N 114169 (5-phenylpyridin-2-yl) 4-(2-methylquinolin-4-yl)piperazine-1-carboxylate::4-(2-methyl-4-quinolinyl)-1-piperazinecarboxylic acid (5-phenyl-2-pyridinyl) ester::4-(2-methyl-4-quinolyl)piperazine-1-carboxylic acid (5-phenyl-2-pyridyl) ester::5-phenylpyridin-2-yl 4-(2-methylquinolin-4-yl)piperazine-1-carboxylate::MLS003874819::SMR002531604::cid_53364507 Disintegrin and metalloproteinase domain-containing protein 17 69378 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114169&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53364507 252663684 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236458 Clc1cccc(CN2CCCCC(NC(=O)c3ccc(COc4ccccc4)cc3)C2=O)c1 InChI=1S/C27H27ClN2O3/c28-23-8-6-7-21(17-23)18-30-16-5-4-11-25(27(30)32)29-26(31)22-14-12-20(13-15-22)19-33-24-9-2-1-3-10-24/h1-3,6-10,12-15,17,25H,4-5,11,16,18-19H2,(H,29,31) PIDNIEAPOSUAOH-UHFFFAOYSA-N 114170 MLS003874499::N-[1-(3-chlorobenzyl)-2-keto-azepan-3-yl]-4-(phenoxymethyl)benzamide::N-[1-[(3-chlorophenyl)methyl]-2-oxidanylidene-azepan-3-yl]-4-(phenoxymethyl)benzamide::N-[1-[(3-chlorophenyl)methyl]-2-oxo-3-azepanyl]-4-(phenoxymethyl)benzamide::N-[1-[(3-chlorophenyl)methyl]-2-oxoazepan-3-yl]-4-(phenoxymethyl)benzamide::SMR002531175::cid_53464094 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114170&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53464094 252663685 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236459 CCOC(=O)N1CCN(CC1)C(=O)C[C@H]1C[C@@]2([C@H](O[C@H](C=C2N(Cc2ccc(Cl)cc2Cl)C1=O)C(C)C)C1CC1)C(=O)OC InChI=1S/C32H41Cl2N3O7/c1-5-43-31(41)36-12-10-35(11-13-36)27(38)14-22-17-32(30(40)42-4)26(16-25(19(2)3)44-28(32)20-6-7-20)37(29(22)39)18-21-8-9-23(33)15-24(21)34/h8-9,15-16,19-20,22,25,28H,5-7,10-14,17-18H2,1-4H3/t22-,25+,28+,32+/m0/s1 LIUDOJGZIULXOM-MQPUOXMMSA-N 114171 (3R,4aR,5R,7S)-3-[2-(4-carbethoxypiperazino)-2-keto-ethyl]-5-cyclopropyl-1-(2,4-dichlorobenzyl)-7-isopropyl-2-keto-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::(3R,4aR,5R,7S)-5-cyclopropyl-1-[(2,4-dichlorophenyl)methyl]-3-[2-(4-ethoxycarbonyl-1-piperazinyl)-2-oxoethyl]-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::MLS003876093::SMR002533038::cid_60157261::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-[(2,4-dichlorophenyl)methyl]-3-[2-(4-ethoxycarbonylpiperazin-1-yl)-2-oxidanylidene-ethyl]-2-oxidanylidene-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-[(2,4-dichlorophenyl)methyl]-3-[2-(4-ethoxycarbonylpiperazin-1-yl)-2-oxoethyl]-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114171&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60157261 252663686 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236460 COC(=O)[C@H](CC(C)C)N(CCc1cn(Cc2ccccc2)nn1)S(=O)(=O)c1ccccc1Br InChI=1S/C24H29BrN4O4S/c1-18(2)15-22(24(30)33-3)29(34(31,32)23-12-8-7-11-21(23)25)14-13-20-17-28(27-26-20)16-19-9-5-4-6-10-19/h4-12,17-18,22H,13-16H2,1-3H3/t22-/m0/s1 OXBCUJPEJIGJGO-QFIPXVFZSA-N 114172 (2S)-2-[(2-bromophenyl)sulfonyl-[2-[1-(phenylmethyl)-4-triazolyl]ethyl]amino]-4-methylpentanoic acid methyl ester::(2S)-2-[2-(1-benzyltriazol-4-yl)ethyl-(2-bromophenyl)sulfonyl-amino]-4-methyl-valeric acid methyl ester::MLS004257117::SMR003082222::cid_60158625::methyl (2S)-2-[(2-bromophenyl)sulfonyl-[2-[1-(phenylmethyl)-1,2,3-triazol-4-yl]ethyl]amino]-4-methyl-pentanoate::methyl (2S)-2-[2-(1-benzyltriazol-4-yl)ethyl-(2-bromophenyl)sulfonylamino]-4-methylpentanoate Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114172 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114172&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60158625 252663687 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236461 COC(=O)[C@]12C[C@H](CC(=O)NCCCCc3ccccc3)C(=O)N(Cc3cccc4ccccc34)C1=C[C@@H](O[C@@H]2C1CC1)C(C)C InChI=1S/C39H46N2O5/c1-26(2)33-23-34-39(38(44)45-3,36(46-33)29-19-20-29)24-31(22-35(42)40-21-10-9-14-27-12-5-4-6-13-27)37(43)41(34)25-30-17-11-16-28-15-7-8-18-32(28)30/h4-8,11-13,15-18,23,26,29,31,33,36H,9-10,14,19-22,24-25H2,1-3H3,(H,40,42)/t31-,33+,36+,39+/m0/s1 QQBTZVNIDLMGRZ-XPXFXHFKSA-N 114173 (3R,4aR,5R,7S)-5-cyclopropyl-1-(1-naphthalenylmethyl)-2-oxo-3-[2-oxo-2-(4-phenylbutylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::(3R,4aR,5R,7S)-5-cyclopropyl-7-isopropyl-2-keto-3-[2-keto-2-(4-phenylbutylamino)ethyl]-1-(1-naphthylmethyl)-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::MLS003876109::SMR002533054::cid_60160041::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-(naphthalen-1-ylmethyl)-2-oxidanylidene-3-[2-oxidanylidene-2-(4-phenylbutylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate::methyl (3R,4aR,5R,7S)-5-cyclopropyl-1-(naphthalen-1-ylmethyl)-2-oxo-3-[2-oxo-2-(4-phenylbutylamino)ethyl]-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114173&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60160041 252663688 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236462 COC(=O)[C@H](CC(C)C)N1Cc2nnn(Cc3ccc(C)cc3)c2-c2cc(F)ccc2S1(=O)=O InChI=1S/C24H27FN4O4S/c1-15(2)11-21(24(30)33-4)29-14-20-23(19-12-18(25)9-10-22(19)34(29,31)32)28(27-26-20)13-17-7-5-16(3)6-8-17/h5-10,12,15,21H,11,13-14H2,1-4H3/t21-/m0/s1 PSPILEFBLDFWMF-NRFANRHFSA-N 114174 (2S)-2-[9-fluoro-1-[(4-methylphenyl)methyl]-6,6-dioxo-4H-triazolo[4,5-d][1,2]benzothiazepin-5-yl]-4-methylpentanoic acid methyl ester::(2S)-2-[9-fluoro-6,6-diketo-1-(4-methylbenzyl)-4H-triazolo[4,5-d][1,2]benzothiazepin-5-yl]-4-methyl-valeric acid methyl ester::MLS004257146::SMR003082251::cid_60160132::methyl (2S)-2-[9-fluoranyl-1-[(4-methylphenyl)methyl]-6,6-bis(oxidanylidene)-4H-[1,2,3]triazolo[4,5-d][1,2]benzothiazepin-5-yl]-4-methyl-pentanoate::methyl (2S)-2-[9-fluoro-1-[(4-methylphenyl)methyl]-6,6-dioxo-4H-triazolo[4,5-d][1,2]benzothiazepin-5-yl]-4-methylpentanoate Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114174 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114174&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60160132 252663689 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236463 COc1cccc(CC(=O)N(Cc2ccccc2)c2ccccc2C(=O)Nc2cc(OC)ccc2OC)c1 InChI=1S/C31H30N2O5/c1-36-24-13-9-12-23(18-24)19-30(34)33(21-22-10-5-4-6-11-22)28-15-8-7-14-26(28)31(35)32-27-20-25(37-2)16-17-29(27)38-3/h4-18,20H,19,21H2,1-3H3,(H,32,35) HYWNCJQOUJEUFW-UHFFFAOYSA-N 114175 2-[N-benzyl-2-(3-methoxyphenyl)acetamido]-N-(2,5-dimethoxyphenyl)benzamide::2-[benzyl-[2-(3-methoxyphenyl)acetyl]amino]-N-(2,5-dimethoxyphenyl)benzamide::MLS004492520::N-(2,5-dimethoxyphenyl)-2-[2-(3-methoxyphenyl)ethanoyl-(phenylmethyl)amino]benzamide::N-(2,5-dimethoxyphenyl)-2-[[2-(3-methoxyphenyl)-1-oxoethyl]-(phenylmethyl)amino]benzamide::SMR003290114::cid_60160256 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114175 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114175&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60160256 252663690 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 236464 Clc1ccc(NC(=O)CN2CCN(CC2)c2nc(cs2)-c2ccccc2)cc1Cl InChI=1S/C21H20Cl2N4OS/c22-17-7-6-16(12-18(17)23)24-20(28)13-26-8-10-27(11-9-26)21-25-19(14-29-21)15-4-2-1-3-5-15/h1-7,12,14H,8-11,13H2,(H,24,28) CUKMGFUQXZUIRT-UHFFFAOYSA-N 114176 MLS004496301::N-(3,4-dichlorophenyl)-2-[4-(4-phenyl-1,3-thiazol-2-yl)piperazin-1-yl]acetamide::N-(3,4-dichlorophenyl)-2-[4-(4-phenyl-1,3-thiazol-2-yl)piperazin-1-yl]ethanamide::N-(3,4-dichlorophenyl)-2-[4-(4-phenyl-2-thiazolyl)-1-piperazinyl]acetamide::N-(3,4-dichlorophenyl)-2-[4-(4-phenylthiazol-2-yl)piperazino]acetamide::SMR003290372::cid_60160275 Disintegrin and metalloproteinase domain-containing protein 17 69562 PubChem 10.7270/Q21J98DJ aid743260 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=114176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=114176&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60160275 252663691 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235499 COc1ccccc1-c1c[nH]nc1-c1ccc(OCC(C)=C)cc1O InChI=1S/C20H20N2O3/c1-13(2)12-25-14-8-9-16(18(23)10-14)20-17(11-21-22-20)15-6-4-5-7-19(15)24-3/h4-11,23H,1,12H2,2-3H3,(H,21,22) HUSXCUQXZQVPSX-UHFFFAOYSA-N 113829 (6E)-6-[4-(2-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-(2-methylprop-2-enoxy)-1-cyclohexa-2,4-dienone::(6E)-6-[4-(2-methoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-(2-methylprop-2-enoxy)cyclohexa-2,4-dien-1-one::(6E)-6-[4-(2-methoxyphenyl)-3-pyrazolin-3-ylidene]-3-(2-methylallyloxy)cyclohexa-2,4-dien-1-one::MLS000083079::SMR000059854::cid_5389737 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113829&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5389737 252663362 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235500 ONC(=O)c1ccc(OC(F)F)cc1 InChI=1S/C8H7F2NO3/c9-8(10)14-6-3-1-5(2-4-6)7(12)11-13/h1-4,8,13H,(H,11,12) FWRXDRYCPUODPN-UHFFFAOYSA-N 113830 4-(difluoromethoxy)-N-hydroxybenzamide::4-(difluoromethoxy)benzenecarbohydroxamic acid::4-[bis(fluoranyl)methoxy]-N-oxidanyl-benzamide::MLS000090171::SMR000024783::cid_3239185 Disintegrin and metalloproteinase domain-containing protein 17 36521 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113830&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3239185 252663363 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235501 Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1ccccc1C(=O)NCc1ccco1 InChI=1S/C25H27N3O5S/c1-18-11-12-19(16-23(18)34(31,32)28-13-5-2-6-14-28)24(29)27-22-10-4-3-9-21(22)25(30)26-17-20-8-7-15-33-20/h3-4,7-12,15-16H,2,5-6,13-14,17H2,1H3,(H,26,30)(H,27,29) OBZURGGDVSLKAS-UHFFFAOYSA-N 68551 MLS000050472::N-(2-{[(2-furylmethyl)amino]carbonyl}phenyl)-4-methyl-3-(1-piperidinylsulfonyl)benzamide::N-[2-(2-furfurylcarbamoyl)phenyl]-4-methyl-3-piperidinosulfonyl-benzamide::N-[2-(furan-2-ylmethylcarbamoyl)phenyl]-4-methyl-3-piperidin-1-ylsulfonyl-benzamide::N-[2-(furan-2-ylmethylcarbamoyl)phenyl]-4-methyl-3-piperidin-1-ylsulfonylbenzamide::N-[2-[(2-furanylmethylamino)-oxomethyl]phenyl]-4-methyl-3-(1-piperidinylsulfonyl)benzamide::SMR000076380::cid_2953887 Disintegrin and metalloproteinase domain-containing protein 17 69480 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68551&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2953887 252646727 ZINC04196747 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235502 ONC(=O)c1ccc(cc1)C(=O)N(C1CCCCC1)C1CCCCC1 InChI=1S/C20H28N2O3/c23-19(21-25)15-11-13-16(14-12-15)20(24)22(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h11-14,17-18,25H,1-10H2,(H,21,23) HRVNXQWSMQVHBV-UHFFFAOYSA-N 113831 4-N,4-N-dicyclohexyl-1-N-hydroxybenzene-1,4-dicarboxamide::MLS000105659::N,N-dicyclohexyl-4-(hydroxycarbamoyl)benzamide::N4,N4-dicyclohexyl-N1-hydroxybenzene-1,4-dicarboxamide::N4,N4-dicyclohexyl-N1-oxidanyl-benzene-1,4-dicarboxamide::SMR000102637::cid_754572 Disintegrin and metalloproteinase domain-containing protein 17 34860 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113831&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 754572 252663364 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235503 Cc1cccc(c1)S(=O)(=O)C(C#N)c1nc2ccccc2nc1N1CCOCC1 InChI=1S/C21H20N4O3S/c1-15-5-4-6-16(13-15)29(26,27)19(14-22)20-21(25-9-11-28-12-10-25)24-18-8-3-2-7-17(18)23-20/h2-8,13,19H,9-12H2,1H3 TZNOEKNHTQZISS-UHFFFAOYSA-N 52125 2-(3-methylphenyl)sulfonyl-2-(3-morpholin-4-ylquinoxalin-2-yl)acetonitrile::2-(3-methylphenyl)sulfonyl-2-(3-morpholin-4-ylquinoxalin-2-yl)ethanenitrile::2-(3-methylphenyl)sulfonyl-2-[3-(4-morpholinyl)-2-quinoxalinyl]acetonitrile::2-(3-morpholinoquinoxalin-2-yl)-2-(m-tolylsulfonyl)acetonitrile::MLS000041681::SMR000044408::cid_663584 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52125&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 663584 252632278 ZINC13130421 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235504 FC(F)(F)c1cnc(CONC(=O)NC=NOCc2ccc(Cl)cc2Cl)c(Cl)c1 InChI=1S/C16H12Cl3F3N4O3/c17-11-2-1-9(12(18)4-11)6-28-25-8-24-15(27)26-29-7-14-13(19)3-10(5-23-14)16(20,21)22/h1-5,8H,6-7H2,(H2,24,25,26,27) ULJGQGAPJVFAKD-UHFFFAOYSA-N 66324 (3E)-1-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]methoxy]-3-[[(2,4-dichlorobenzyl)oxyamino]methylene]urea::1-[[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]methoxy]-3-[[(2,4-dichlorophenyl)methoxyamino]methylidene]urea::1-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methoxy]-3-[[(2,4-dichlorophenyl)methoxyamino]methylidene]urea::1-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]methoxy]-3-[[(2,4-dichlorobenzyl)oxyamino]methylene]urea::1-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methoxy]-3-[[(2,4-dichlorophenyl)methoxyamino]methylidene]urea::MLS000539628::N-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]methoxy}-N-({[(2,4-dichlorobenzyl)oxy]imino}methyl)urea::SMR000125286::cid_3409513 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=66324 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=66324&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16412947 252644649 ZINC13146607 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235505 [O-][N+](=O)c1cccnc1N1CCC(CC1)c1cc(n[nH]1)-c1cccc(c1)C(F)(F)F InChI=1S/C20H18F3N5O2/c21-20(22,23)15-4-1-3-14(11-15)17-12-16(25-26-17)13-6-9-27(10-7-13)19-18(28(29)30)5-2-8-24-19/h1-5,8,11-13H,6-7,9-10H2,(H,25,26) GQQISVVLMAVEAG-UHFFFAOYSA-N 113832 1-(3-nitro-2-pyridinyl)-4-{5-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}piperidine::3-nitro-2-[4-[3-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl]-1-piperidinyl]pyridine::3-nitro-2-[4-[3-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl]piperidin-1-yl]pyridine::3-nitro-2-[4-[3-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl]piperidino]pyridine::MLS000541426::SMR000126284::cid_3756811 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113832&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3756811 252663365 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235506 COc1ccc(-c2n[nH]c(C)c2-c2cnn(c2)-c2ccccc2)c(O)c1C InChI=1S/C21H20N4O2/c1-13-18(27-3)10-9-17(21(13)26)20-19(14(2)23-24-20)15-11-22-25(12-15)16-7-5-4-6-8-16/h4-12,26H,1-3H3,(H,23,24) LMOKCTBKPVULOX-UHFFFAOYSA-N 113833 (6Z)-3-methoxy-2-methyl-6-[5-methyl-4-(1-phenyl-4-pyrazolyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6Z)-3-methoxy-2-methyl-6-[5-methyl-4-(1-phenylpyrazol-4-yl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6Z)-3-methoxy-2-methyl-6-[5-methyl-4-(1-phenylpyrazol-4-yl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::3-methoxy-2-methyl-6-(5-methyl-1'-phenyl-1H,1'H-4,4'-bipyrazol-3-yl)phenol::MLS000530730::SMR000135708::cid_5505376 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113833&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5505376 252663366 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235507 COc1ccc(cc1O)C(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12 InChI=1S/C24H20N2O2/c1-28-23-11-10-15(12-22(23)27)24(18-13-25-20-8-4-2-6-16(18)20)19-14-26-21-9-5-3-7-17(19)21/h2-14,24-27H,1H3 CWMPUSKUSXTPAT-UHFFFAOYSA-N 41667 5-[bis(1H-indol-3-yl)methyl]-2-methoxy-phenol::5-[bis(1H-indol-3-yl)methyl]-2-methoxyphenol::MLS000522851::SMR000128117::cid_7118245 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41667&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 7118245 252622388 ZINC04165015 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235508 COc1cc(OC)c(cc1OC)C1C(C#N)C(=N)OC2=C1C(=O)CC(C)(C)C2 InChI=1S/C21H24N2O5/c1-21(2)8-13(24)19-17(9-21)28-20(23)12(10-22)18(19)11-6-15(26-4)16(27-5)7-14(11)25-3/h6-7,12,18,23H,8-9H2,1-5H3 JMVHPZCKNXDRRE-UHFFFAOYSA-N 52212 2-amino-4-asaryl-5-keto-7,7-dimethyl-6,8-dihydro-4H-chromene-3-carbonitrile::2-amino-7,7-dimethyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-6,8-dihydro-4H-1-benzopyran-3-carbonitrile::2-amino-7,7-dimethyl-5-oxo-4-(2,4,5-trimethoxyphenyl)-6,8-dihydro-4H-chromene-3-carbonitrile::2-azanyl-7,7-dimethyl-5-oxidanylidene-4-(2,4,5-trimethoxyphenyl)-6,8-dihydro-4H-chromene-3-carbonitrile::MLS000104773::SMR000054706::cid_2828670 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91897036 252632362 ZINC13144203 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235509 Fc1c(F)c(c(F)c(F)c1N=NCc1cccs1)C(F)(F)F InChI=1S/C12H5F7N2S/c13-7-6(12(17,18)19)8(14)10(16)11(9(7)15)21-20-4-5-2-1-3-22-5/h1-3H,4H2 JXRCJPMUXUGKLA-UHFFFAOYSA-N 67828 2,3,5,6-tetrafluoro-N-(thiophen-2-ylmethylideneamino)-4-(trifluoromethyl)aniline::2,3,5,6-tetrakis(fluoranyl)-N-(thiophen-2-ylmethylideneamino)-4-(trifluoromethyl)aniline::2-thiophenecarbaldehyde [2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]hydrazone::MLS000533109::SMR000140547::[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-(2-thenylideneamino)amine::[2,3,5,6-tetrafluoro-4-(trifluoromethyl)phenyl]-[(Z)-2-thenylideneamino]amine::cid_2856530 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67828&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91897710 252646115 ZINC08671188 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235510 Cc1ccccc1NC(=NOCc1ccc(Cl)cc1Cl)c1nonc1N InChI=1S/C17H15Cl2N5O2/c1-10-4-2-3-5-14(10)21-17(15-16(20)23-26-22-15)24-25-9-11-6-7-12(18)8-13(11)19/h2-8H,9H2,1H3,(H2,20,23)(H,21,24) MXSNYIQUCKGAIC-UHFFFAOYSA-N 39671 4-amino-N'-[(2,4-dichlorobenzyl)oxy]-N-(2-methylphenyl)-1,2,5-oxadiazole-3-carboximidamide::4-amino-N-(2,4-dichlorobenzyl)oxy-N'-(o-tolyl)furazan-3-carboxamidine::4-amino-N-[(2,4-dichlorophenyl)methoxy]-N'-(2-methylphenyl)-1,2,5-oxadiazole-3-carboximidamide::4-azanyl-N-[(2,4-dichlorophenyl)methoxy]-N'-(2-methylphenyl)-1,2,5-oxadiazole-3-carboximidamide::MLS000532789::SMR000140227::cid_4060248 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=39671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=39671&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4060248 252620557 ZINC13286594 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235511 Cc1ccccc1CN(c1ccc(cc1)C(=O)Nc1ccccc1C(=O)NCc1ccco1)S(C)(=O)=O InChI=1S/C28H27N3O5S/c1-20-8-3-4-9-22(20)19-31(37(2,34)35)23-15-13-21(14-16-23)27(32)30-26-12-6-5-11-25(26)28(33)29-18-24-10-7-17-36-24/h3-17H,18-19H2,1-2H3,(H,29,33)(H,30,32) OJHYWCNIXIGDGX-UHFFFAOYSA-N 113835 MLS000531720::N-(2-furanylmethyl)-2-[[[4-[(2-methylphenyl)methyl-methylsulfonylamino]phenyl]-oxomethyl]amino]benzamide::N-(2-furfuryl)-2-[[4-[mesyl-(2-methylbenzyl)amino]benzoyl]amino]benzamide::N-(2-furylmethyl)-2-({4-[(2-methylbenzyl)(methylsulfonyl)amino]benzoyl}amino)benzamide::N-(furan-2-ylmethyl)-2-[[4-[(2-methylphenyl)methyl-methylsulfonyl-amino]phenyl]carbonylamino]benzamide::N-(furan-2-ylmethyl)-2-[[4-[(2-methylphenyl)methyl-methylsulfonylamino]benzoyl]amino]benzamide::SMR000136698::cid_1304148 Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113835&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1304148 252663367 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235512 Cn1nc(nc2c1nc(=O)n(C)c2=O)-c1ccccn1 InChI=1S/C12H10N6O2/c1-17-11(19)8-10(15-12(17)20)18(2)16-9(14-8)7-5-3-4-6-13-7/h3-6H,1-2H3 HDXJYJIPXWVRSM-UHFFFAOYSA-N 51771 1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione::1,6-dimethyl-3-(2-pyridinyl)pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1,6-dimethyl-3-(2-pyridyl)pyrimido[5,4-e][1,2,4]triazine-5,7-quinone::1,6-dimethyl-3-pyridin-2-yl-pyrimido[5,4-e][1,2,4]triazine-5,7-dione::1,6-dimethyl-3-pyridin-2-ylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::MLS000684008::SMR000291658::cid_906542 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51771 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51771&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 906542 252631950 ZINC01164767 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235513 Cn1cc(cc1C(=O)NN=C(N)COc1ccc(Cl)cc1Cl)C(=O)c1ccc(Cl)cc1Cl InChI=1S/C21H16Cl4N4O3/c1-29-9-11(20(30)14-4-2-12(22)7-15(14)24)6-17(29)21(31)28-27-19(26)10-32-18-5-3-13(23)8-16(18)25/h2-9H,10H2,1H3,(H2,26,27)(H,28,31) FGFLTGMJXBFEJB-UHFFFAOYSA-N 57171 4-(2,4-dichlorobenzoyl)-N'-[2-(2,4-dichlorophenoxy)ethanimidoyl]-1-methyl-1H-pyrrole-2-carbohydrazide::MLS000539576::N-[(Z)-[1-amino-2-(2,4-dichlorophenoxy)ethylidene]amino]-4-(2,4-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide::N-[[1-amino-2-(2,4-dichlorophenoxy)ethylidene]amino]-4-(2,4-dichlorobenzoyl)-1-methyl-pyrrole-2-carboxamide::N-[[1-amino-2-(2,4-dichlorophenoxy)ethylidene]amino]-4-(2,4-dichlorobenzoyl)-1-methylpyrrole-2-carboxamide::N-[[1-amino-2-(2,4-dichlorophenoxy)ethylidene]amino]-4-[(2,4-dichlorophenyl)-oxomethyl]-1-methyl-2-pyrrolecarboxamide::N-[[1-azanyl-2-[2,4-bis(chloranyl)phenoxy]ethylidene]amino]-4-(2,4-dichlorophenyl)carbonyl-1-methyl-pyrrole-2-carboxamide::SMR000125234::cid_3726014 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=57171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=57171&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16412938 252637107 ZINC18152612 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235514 O=S(=O)(N\N=C\c1cn(Cc2ccccc2)c2ccccc12)c1ccccc1 InChI=1S/C22H19N3O2S/c26-28(27,20-11-5-2-6-12-20)24-23-15-19-17-25(16-18-9-3-1-4-10-18)22-14-8-7-13-21(19)22/h1-15,17,24H,16H2/b23-15+ TYFHLNFSLBQEQI-HZHRSRAPSA-N 113837 MLS000530676::N'-[(1-benzyl-1H-indol-3-yl)methylene]benzenesulfonohydrazide::N-[(E)-(1-benzylindol-3-yl)methyleneamino]benzenesulfonamide::N-[(E)-(1-benzylindol-3-yl)methylideneamino]benzenesulfonamide::N-[(E)-[1-(phenylmethyl)-3-indolyl]methylideneamino]benzenesulfonamide::N-[(E)-[1-(phenylmethyl)indol-3-yl]methylideneamino]benzenesulfonamide::SMR000135654::cid_6894189 Disintegrin and metalloproteinase domain-containing protein 17 69496 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113837&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6894189 252663368 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235515 O=C1N(CCCc2nc(no2)-c2ccncc2)C(=O)c2ccccc12 InChI=1S/C18H14N4O3/c23-17-13-4-1-2-5-14(13)18(24)22(17)11-3-6-15-20-16(21-25-15)12-7-9-19-10-8-12/h1-2,4-5,7-10H,3,6,11H2 AGWWZCICEUHAPF-UHFFFAOYSA-N 52260 2-[3-(3-pyridin-4-yl-1,2,4-oxadiazol-5-yl)propyl]isoindole-1,3-dione::2-[3-[3-(4-pyridyl)-1,2,4-oxadiazol-5-yl]propyl]isoindoline-1,3-quinone::2-{3-[3-(4-pyridinyl)-1,2,4-oxadiazol-5-yl]propyl}-1H-isoindole-1,3(2H)-dione::MLS000536882::SMR000143529::cid_2953744 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52260 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52260&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2953744 252632407 ZINC13121940 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235516 O=C(NN=Cc1cccc2ccccc12)C(NC(=O)c1ccccc1)c1n[nH]c(=O)c2ccccc12 InChI=1S/C28H21N5O3/c34-26(19-10-2-1-3-11-19)30-25(24-22-15-6-7-16-23(22)27(35)33-31-24)28(36)32-29-17-20-13-8-12-18-9-4-5-14-21(18)20/h1-17,25H,(H,30,34)(H,32,36)(H,33,35) FWUWEAZKNWCZME-UHFFFAOYSA-N 113838 MLS000551245::N-[2-[(2E)-2-(1-naphthalenylmethylidene)hydrazinyl]-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl]benzamide::N-[2-[(2E)-2-(naphthalen-1-ylmethylidene)hydrazinyl]-2-oxidanylidene-1-(4-oxidanylidene-3H-phthalazin-1-yl)ethyl]benzamide::N-[2-[(2E)-2-(naphthalen-1-ylmethylidene)hydrazinyl]-2-oxo-1-(4-oxo-3H-phthalazin-1-yl)ethyl]benzamide::N-[2-keto-1-(4-keto-3H-phthalazin-1-yl)-2-[(N'E)-N'-(1-naphthylmethylene)hydrazino]ethyl]benzamide::N-{(4-Hydroxy-phthalazin-1-yl)-[1-naphthalen-1-yl-meth-(E)-ylidene-hydrazinocarbonyl]-methyl}-benzami de::SMR000145171::cid_9638457 Disintegrin and metalloproteinase domain-containing protein 17 69473 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113838&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9638457 252663369 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235517 COc1ccc(cc1)-c1c(C)[nH]nc1-c1ccc(OCC(C)=C)cc1O InChI=1S/C21H22N2O3/c1-13(2)12-26-17-9-10-18(19(24)11-17)21-20(14(3)22-23-21)15-5-7-16(25-4)8-6-15/h5-11,24H,1,12H2,2-4H3,(H,22,23) FHWZHNLEUUCFPV-UHFFFAOYSA-N 113839 (6E)-6-[4-(4-methoxyphenyl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-3-(2-methylprop-2-enoxy)-1-cyclohexa-2,4-dienone::(6E)-6-[4-(4-methoxyphenyl)-5-methyl-1,2-dihydropyrazol-3-ylidene]-3-(2-methylprop-2-enoxy)cyclohexa-2,4-dien-1-one::(6E)-6-[4-(4-methoxyphenyl)-5-methyl-3-pyrazolin-3-ylidene]-3-(2-methylallyloxy)cyclohexa-2,4-dien-1-one::2-[4-(4-Methoxy-phenyl)-5-methyl-1H-pyrazol-3-yl]-5-(2-methyl-allyloxy)-phenol::MLS000551740::SMR000145665::cid_9551787 Disintegrin and metalloproteinase domain-containing protein 17 69562 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113839&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9551787 252663370 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235518 Cc1ccc(cc1)C1C(C=C2SC(S)=NC2=O)=C(Oc2ccccc12)c1cccs1 InChI=1S/C24H17NO2S3/c1-14-8-10-15(11-9-14)21-16-5-2-3-6-18(16)27-22(19-7-4-12-29-19)17(21)13-20-23(26)25-24(28)30-20/h2-13,21H,1H3,(H,25,26,28) XRSJPTLZINOZRY-UHFFFAOYSA-N 50100 (5E)-5-[[4-(4-methylphenyl)-2-thiophen-2-yl-4H-1-benzopyran-3-yl]methylidene]-2-sulfanylidene-4-thiazolidinone::(5E)-5-[[4-(4-methylphenyl)-2-thiophen-2-yl-4H-chromen-3-yl]methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one::(5E)-5-[[4-(p-tolyl)-2-(2-thienyl)-4H-chromen-3-yl]methylene]-2-thioxo-thiazolidin-4-one::5-[1-(2-Thiophen-2-yl-4-p-tolyl-4H-chromen-3-yl)-meth-(E)-ylidene]-2-thioxo-thiazolidin-4-one::MLS000595348::SMR000149871::cid_9551861 Disintegrin and metalloproteinase domain-containing protein 17 33734 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50100&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9551861 252630370 ZINC13123539 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235519 CN(C)c1ccc(NC(=O)c2cn(nc2-c2cccs2)-c2ccccc2)cc1 InChI=1S/C22H20N4OS/c1-25(2)17-12-10-16(11-13-17)23-22(27)19-15-26(18-7-4-3-5-8-18)24-21(19)20-9-6-14-28-20/h3-15H,1-2H3,(H,23,27) LOPGINRZVURMPZ-UHFFFAOYSA-N 50102 MLS000536683::N-[4-(dimethylamino)phenyl]-1-phenyl-3-(2-thienyl)pyrazole-4-carboxamide::N-[4-(dimethylamino)phenyl]-1-phenyl-3-thiophen-2-yl-4-pyrazolecarboxamide::N-[4-(dimethylamino)phenyl]-1-phenyl-3-thiophen-2-yl-pyrazole-4-carboxamide::N-[4-(dimethylamino)phenyl]-1-phenyl-3-thiophen-2-ylpyrazole-4-carboxamide::SMR000155614::cid_2336084 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2336084 252630372 ZINC20755942 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235520 Cc1cc(NC(=O)c2c(F)cccc2Cl)n(n1)-c1nc2ccccc2[nH]1 InChI=1S/C18H13ClFN5O/c1-10-9-15(23-17(26)16-11(19)5-4-6-12(16)20)25(24-10)18-21-13-7-2-3-8-14(13)22-18/h2-9H,1H3,(H,21,22)(H,23,26) GSJAVDQBOSAGQM-UHFFFAOYSA-N 48499 MLS000567238::N-[2-(1H-benzimidazol-2-yl)-5-methyl-3-pyrazolyl]-2-chloro-6-fluorobenzamide::N-[2-(1H-benzimidazol-2-yl)-5-methyl-pyrazol-3-yl]-2-chloranyl-6-fluoranyl-benzamide::N-[2-(1H-benzimidazol-2-yl)-5-methyl-pyrazol-3-yl]-2-chloro-6-fluoro-benzamide::N-[2-(1H-benzimidazol-2-yl)-5-methylpyrazol-3-yl]-2-chloro-6-fluorobenzamide::SMR000153977::cid_3363185 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48499&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3363185 252628792 ZINC05269964 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235521 CCc1ccc(\C=c2/s\c(=C/C(=O)C(C)(C)C)[nH]c2=O)cc1 InChI=1S/C18H21NO2S/c1-5-12-6-8-13(9-7-12)10-14-17(21)19-16(22-14)11-15(20)18(2,3)4/h6-11H,5H2,1-4H3,(H,19,21)/b14-10-,16-11- XACCTLUDPKUWHC-JBBFUIBGSA-N 113840 (2Z,5Z)-2-(3,3-dimethyl-2-oxidanylidene-butylidene)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidin-4-one::(2Z,5Z)-2-(3,3-dimethyl-2-oxobutylidene)-5-[(4-ethylphenyl)methylidene]-1,3-thiazolidin-4-one::(2Z,5Z)-2-(3,3-dimethyl-2-oxobutylidene)-5-[(4-ethylphenyl)methylidene]-4-thiazolidinone::(2Z,5Z)-5-(4-ethylbenzylidene)-2-(2-keto-3,3-dimethyl-butylidene)thiazolidin-4-one::MLS000567275::SMR000154050::cid_5701556 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113840&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5701556 252663371 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235522 CCCCn1c(SCc2nc(N)nc(Nc3ccccc3C)n2)nc2ccccc2c1=O InChI=1S/C23H25N7OS/c1-3-4-13-30-20(31)16-10-6-8-12-18(16)26-23(30)32-14-19-27-21(24)29-22(28-19)25-17-11-7-5-9-15(17)2/h5-12H,3-4,13-14H2,1-2H3,(H3,24,25,27,28,29) HYSJPKNMAAMTAQ-UHFFFAOYSA-N 113841 2-[[4-amino-6-(2-methylanilino)-1,3,5-triazin-2-yl]methylsulfanyl]-3-butylquinazolin-4-one::2-[[4-amino-6-(2-methylanilino)-1,3,5-triazin-2-yl]methylthio]-3-butyl-4-quinazolinone::2-[[4-amino-6-(o-toluidino)-s-triazin-2-yl]methylthio]-3-butyl-quinazolin-4-one::2-[[4-azanyl-6-[(2-methylphenyl)amino]-1,3,5-triazin-2-yl]methylsulfanyl]-3-butyl-quinazolin-4-one::MLS000567406::SMR000154064::cid_2604369 Disintegrin and metalloproteinase domain-containing protein 17 69497 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113841&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2604369 252663372 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235523 Cc1cc(C)cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)c3ccc(Br)o3)cc2)c1 InChI=1S/C20H18BrN3O4S2/c1-12-9-13(2)11-15(10-12)24-30(26,27)16-5-3-14(4-6-16)22-20(29)23-19(25)17-7-8-18(21)28-17/h3-11,24H,1-2H3,(H2,22,23,25,29) JCZWJROKBALQHR-UHFFFAOYSA-N 113842 4-({[(5-bromo-2-furoyl)amino]carbothioyl}amino)-N-(3,5-dimethylphenyl)benzenesulfonamide::5-bromanyl-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]phenyl]carbamothioyl]furan-2-carboxamide::5-bromo-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]anilino]-sulfanylidenemethyl]-2-furancarboxamide::5-bromo-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]phenyl]carbamothioyl]furan-2-carboxamide::5-bromo-N-[[4-[(3,5-dimethylphenyl)sulfamoyl]phenyl]thiocarbamoyl]-2-furamide::MLS000540802::SMR000162350::cid_1014972 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113842&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1014972 252663373 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235524 Cc1cccc(OCC(=O)NNC(=O)c2cc3ccccc3oc2=O)c1 InChI=1S/C19H16N2O5/c1-12-5-4-7-14(9-12)25-11-17(22)20-21-18(23)15-10-13-6-2-3-8-16(13)26-19(15)24/h2-10H,11H2,1H3,(H,20,22)(H,21,23) VSFOYBSBQQMBIK-UHFFFAOYSA-N 113843 2-keto-N'-[2-(3-methylphenoxy)acetyl]chromene-3-carbohydrazide::MLS000324956::N'-[(3-methylphenoxy)acetyl]-2-oxo-2H-chromene-3-carbohydrazide::N'-[2-(3-methylphenoxy)-1-oxoethyl]-2-oxo-1-benzopyran-3-carbohydrazide::N'-[2-(3-methylphenoxy)acetyl]-2-oxochromene-3-carbohydrazide::N'-[2-(3-methylphenoxy)ethanoyl]-2-oxidanylidene-chromene-3-carbohydrazide::SMR000159579::cid_996186 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113843&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 996186 252663374 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235525 COc1cc(\C=N\NC(=O)COc2ccc(Cl)cc2)ccc1OS(=O)(=O)c1ccc(C)cc1 InChI=1S/C23H21ClN2O6S/c1-16-3-10-20(11-4-16)33(28,29)32-21-12-5-17(13-22(21)30-2)14-25-26-23(27)15-31-19-8-6-18(24)7-9-19/h3-14H,15H2,1-2H3,(H,26,27)/b25-14+ QWTHCJLEDVZWJN-AFUMVMLFSA-N 96310 4-methylbenzenesulfonic acid [4-[(E)-[[2-(4-chlorophenoxy)-1-oxoethyl]hydrazinylidene]methyl]-2-methoxyphenyl] ester::4-methylbenzenesulfonic acid [4-[(E)-[[2-(4-chlorophenoxy)acetyl]hydrazono]methyl]-2-methoxy-phenyl] ester::4-{2-[(4-chlorophenoxy)acetyl]carbohydrazonoyl}-2-methoxyphenyl 4-methylbenzenesulfonate::MLS000324668::SMR000163796::[4-[(E)-[2-(4-chloranylphenoxy)ethanoylhydrazinylidene]methyl]-2-methoxy-phenyl] 4-methylbenzenesulfonate::[4-[(E)-[[2-(4-chlorophenoxy)acetyl]hydrazinylidene]methyl]-2-methoxyphenyl] 4-methylbenzenesulfonate::cid_6872703 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=96310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=96310&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6872703 164037554 ZINC02077346 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235526 O=C(Cn1cncn1)NN=Cc1c2ccccc2cc2ccccc12 InChI=1S/C19H15N5O/c25-19(11-24-13-20-12-22-24)23-21-10-18-16-7-3-1-5-14(16)9-15-6-2-4-8-17(15)18/h1-10,12-13H,11H2,(H,23,25) VOSSNDIFQDRPCM-UHFFFAOYSA-N 52356 MLS000552707::N-(9-anthracenylmethylideneamino)-2-(1,2,4-triazol-1-yl)acetamide::N-(9-anthrylmethyleneamino)-2-(1,2,4-triazol-1-yl)acetamide::N-(anthracen-9-ylmethylideneamino)-2-(1,2,4-triazol-1-yl)acetamide::N-(anthracen-9-ylmethylideneamino)-2-(1,2,4-triazol-1-yl)ethanamide::SMR000146222::[1,2,4]Triazol-1-yl-acetic acid [1-anthracen-9-yl-meth-(E)-ylidene]-hydrazide::cid_947898 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52356 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52356&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6884287 252632499 ZINC00667182 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235527 CCOc1ccc(\C=N\NC(=O)Cc2csc(Nc3cccc(c3)C(F)(F)F)n2)c(OCC)c1 InChI=1S/C23H23F3N4O3S/c1-3-32-19-9-8-15(20(12-19)33-4-2)13-27-30-21(31)11-18-14-34-22(29-18)28-17-7-5-6-16(10-17)23(24,25)26/h5-10,12-14H,3-4,11H2,1-2H3,(H,28,29)(H,30,31)/b27-13+ VYEBBQUIGYMRMZ-UVHMKAGCSA-N 113844 MLS000541159::N'-(2,4-diethoxybenzylidene)-2-{2-[3-(trifluoromethyl)anilino]-1,3-thiazol-4-yl}acetohydrazide::N-[(E)-(2,4-diethoxybenzylidene)amino]-2-[2-[3-(trifluoromethyl)anilino]thiazol-4-yl]acetamide::N-[(E)-(2,4-diethoxyphenyl)methylideneamino]-2-[2-[3-(trifluoromethyl)anilino]-1,3-thiazol-4-yl]acetamide::N-[(E)-(2,4-diethoxyphenyl)methylideneamino]-2-[2-[3-(trifluoromethyl)anilino]-4-thiazolyl]acetamide::N-[(E)-(2,4-diethoxyphenyl)methylideneamino]-2-[2-[[3-(trifluoromethyl)phenyl]amino]-1,3-thiazol-4-yl]ethanamide::SMR000161114::cid_6876390 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113844&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6876390 252663375 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235528 Clc1ccc(cc1)C1N(CCc2c1[nH]c1ccccc21)C(=O)c1cccs1 InChI=1S/C22H17ClN2OS/c23-15-9-7-14(8-10-15)21-20-17(16-4-1-2-5-18(16)24-20)11-12-25(21)22(26)19-6-3-13-27-19/h1-10,13,21,24H,11-12H2 XGIUNRTXJGFTJI-UHFFFAOYSA-N 113845 1-(4-chlorophenyl)-2-(2-thienylcarbonyl)-2,3,4,9-tetrahydro-1H-beta-carboline::MLS000544536::SMR000159578::[1-(4-chlorophenyl)-1,3,4,9-tetrahydro-beta-carbolin-2-yl]-(2-thienyl)methanone::[1-(4-chlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-thiophen-2-yl-methanone::[1-(4-chlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]-thiophen-2-ylmethanone::cid_3610662 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113845&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3610662 252663376 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235529 Oc1cc(N(CCc2ccccc2)C(=S)Nc2cc(Cl)ccc2Cl)c(O)n1-c1c(Cl)cccc1Cl InChI=1S/C25H19Cl4N3O2S/c26-16-9-10-17(27)20(13-16)30-25(35)31(12-11-15-5-2-1-3-6-15)21-14-22(33)32(24(21)34)23-18(28)7-4-8-19(23)29/h1-10,13-14,33-34H,11-12H2,(H,30,35) LRDCYFHUFPCLDW-UHFFFAOYSA-N 113846 3-(2,5-dichlorophenyl)-1-[1-(2,6-dichlorophenyl)-2,5-diketo-pyrrolidin-3-yl]-1-phenethyl-thiourea::3-(2,5-dichlorophenyl)-1-[1-(2,6-dichlorophenyl)-2,5-dioxo-3-pyrrolidinyl]-1-(2-phenylethyl)thiourea::3-(2,5-dichlorophenyl)-1-[1-(2,6-dichlorophenyl)-2,5-dioxopyrrolidin-3-yl]-1-(2-phenylethyl)thiourea::3-[2,5-bis(chloranyl)phenyl]-1-[1-[2,6-bis(chloranyl)phenyl]-2,5-bis(oxidanylidene)pyrrolidin-3-yl]-1-(2-phenylethyl)thiourea::MLS000324794::N'-(2,5-dichlorophenyl)-N-[1-(2,6-dichlorophenyl)-2,5-dioxo-3-pyrrolidinyl]-N-(2-phenylethyl)thiourea::SMR000159850::cid_3438153 Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113846&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899698 252663377 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235530 CC(Nc1ccccc1C)C(=O)N\N=C\c1ccccc1OCc1cccc(Br)c1 InChI=1S/C24H24BrN3O2/c1-17-8-3-5-12-22(17)27-18(2)24(29)28-26-15-20-10-4-6-13-23(20)30-16-19-9-7-11-21(25)14-19/h3-15,18,27H,16H2,1-2H3,(H,28,29)/b26-15+ GLMVTVQTPRBKPQ-CVKSISIWSA-N 113847 MLS000544324::N'-{2-[(3-bromobenzyl)oxy]benzylidene}-2-(2-toluidino)propanohydrazide::N-[(E)-[2-(3-bromobenzyl)oxybenzylidene]amino]-2-(o-toluidino)propionamide::N-[(E)-[2-[(3-bromophenyl)methoxy]phenyl]methylideneamino]-2-(2-methylanilino)propanamide::N-[(E)-[2-[(3-bromophenyl)methoxy]phenyl]methylideneamino]-2-[(2-methylphenyl)amino]propanamide::SMR000159646::cid_9620252 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113847&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9620252 252663378 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235531 Clc1ccc(SCC(=O)N2CCC(CC2)c2nc3ccccc3s2)c(Cl)c1 InChI=1S/C20H18Cl2N2OS2/c21-14-5-6-17(15(22)11-14)26-12-19(25)24-9-7-13(8-10-24)20-23-16-3-1-2-4-18(16)27-20/h1-6,11,13H,7-10,12H2 YEMNHTMAEPPCQS-UHFFFAOYSA-N 113848 1-[4-(1,3-benzothiazol-2-yl)-1-piperidinyl]-2-[(2,4-dichlorophenyl)thio]ethanone::1-[4-(1,3-benzothiazol-2-yl)piperidin-1-yl]-2-(2,4-dichlorophenyl)sulfanyl-ethanone::1-[4-(1,3-benzothiazol-2-yl)piperidin-1-yl]-2-(2,4-dichlorophenyl)sulfanylethanone::1-[4-(1,3-benzothiazol-2-yl)piperidino]-2-[(2,4-dichlorophenyl)sulfanyl]-1-ethanone::1-[4-(1,3-benzothiazol-2-yl)piperidino]-2-[(2,4-dichlorophenyl)thio]ethanone::MLS000326867::SMR000179502::cid_1479989 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113848&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1479989 252663379 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235532 C\C(\C=C1/N=C(SCc2ccccc2Cl)SC1=O)=C/c1ccccc1 InChI=1S/C20H16ClNOS2/c1-14(11-15-7-3-2-4-8-15)12-18-19(23)25-20(22-18)24-13-16-9-5-6-10-17(16)21/h2-12H,13H2,1H3/b14-11+,18-12- NVWXUGMSOZSZRF-UJUKKVGJSA-N 52400 (4Z)-2-[(2-chlorobenzyl)thio]-4-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-2-thiazolin-5-one::(4Z)-2-[(2-chlorophenyl)methylsulfanyl]-4-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-1,3-thiazol-5-one::(4Z)-2-[(2-chlorophenyl)methylsulfanyl]-4-[(E)-2-methyl-3-phenylprop-2-enylidene]-1,3-thiazol-5-one::(4Z)-2-[(2-chlorophenyl)methylthio]-4-[(E)-2-methyl-3-phenylprop-2-enylidene]-5-thiazolone::2-[(2-chlorobenzyl)thio]-4-(2-methyl-3-phenyl-2-propen-1-ylidene)-1,3-thiazol-5(4H)-one::MLS000576764::SMR000208979::cid_1769017 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52400&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1769017 252632543 ZINC13143353 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235533 CCCNc1c(F)c(F)c2c(C)c3ccccc3nc2c1F InChI=1S/C17H15F3N2/c1-3-8-21-17-14(19)13(18)12-9(2)10-6-4-5-7-11(10)22-16(12)15(17)20/h4-7,21H,3,8H2,1-2H3 YCRPGBKFKHMDMV-UHFFFAOYSA-N 52404 1,2,4-trifluoro-9-methyl-N-propyl-3-acridinamine::1,2,4-trifluoro-9-methyl-N-propylacridin-3-amine::1,2,4-tris(fluoranyl)-9-methyl-N-propyl-acridin-3-amine::MLS000580574::SMR000199463::cid_2951212::propyl-(1,2,4-trifluoro-9-methyl-acridin-3-yl)amine Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52404&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2951212 252632547 ZINC13142726 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235534 Cc1nnc(=O)[nH]c1N=[NH+]C[c-]1ccc(=O)c(c1)[N+]([O-])=O InChI=1S/C11H9N6O4/c1-6-10(13-11(19)16-14-6)15-12-5-7-2-3-9(18)8(4-7)17(20)21/h2-4H,5H2,1H3,(H,13,16,19)/q-1/p+1 ZKRKMSQXRMJAGC-UHFFFAOYSA-O 52424 4-hydroxy-3-nitrobenzaldehyde (6-methyl-3-oxo-2,3-dihydro-1,2,4-triazin-5-yl)hydrazone::5-[N'-[(Z)-(4-keto-3-nitro-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazino]-6-methyl-2H-1,2,4-triazin-3-one::6-methyl-5-[2-[(Z)-(3-nitro-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-2H-1,2,4-triazin-3-one::6-methyl-5-[2-[(Z)-(3-nitro-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]hydrazinyl]-2H-1,2,4-triazin-3-one::6-methyl-5-[[(Z)-(3-nitro-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]hydrazo]-2H-1,2,4-triazin-3-one::MLS000585487::SMR000207469::cid_12004549 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52424 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52424&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91897062 252632567 ZINC02324058 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235535 O=C(Nc1c(C#N)c(c(-c2ccccc2)n1Cc1ccco1)-c1ccccc1)c1cccs1 InChI=1S/C27H19N3O2S/c28-17-22-24(19-9-3-1-4-10-19)25(20-11-5-2-6-12-20)30(18-21-13-7-15-32-21)26(22)29-27(31)23-14-8-16-33-23/h1-16H,18H2,(H,29,31) CTZROLIJCRVSTP-UHFFFAOYSA-N 72073 MLS000545991::N-[3-cyano-1-(2-furanylmethyl)-4,5-diphenyl-2-pyrrolyl]-2-thiophenecarboxamide::N-[3-cyano-1-(2-furfuryl)-4,5-diphenyl-pyrrol-2-yl]thiophene-2-carboxamide::N-[3-cyano-1-(2-furylmethyl)-4,5-diphenyl-1H-pyrrol-2-yl]thiophene-2-carboxamide::N-[3-cyano-1-(furan-2-ylmethyl)-4,5-diphenyl-pyrrol-2-yl]thiophene-2-carboxamide::N-[3-cyano-1-(furan-2-ylmethyl)-4,5-diphenylpyrrol-2-yl]thiophene-2-carboxamide::SMR000162939::cid_1050694 Disintegrin and metalloproteinase domain-containing protein 17 69495 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72073 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72073&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1050694 252649339 ZINC00728972 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235536 Cc1ccc(cc1)C(=S)NCS(=O)(=O)c1ccc(C)cc1 InChI=1S/C16H17NO2S2/c1-12-3-7-14(8-4-12)16(20)17-11-21(18,19)15-9-5-13(2)6-10-15/h3-10H,11H2,1-2H3,(H,17,20) JPRGFUXVUPWSIO-UHFFFAOYSA-N 113849 4-methyl-N-(tosylmethyl)thiobenzamide::4-methyl-N-[(4-methylphenyl)sulfonylmethyl]benzenecarbothioamide::4-methyl-N-{[(4-methylphenyl)sulfonyl]methyl}benzenecarbothioamide::MLS000537085::SMR000160411::cid_845855 Disintegrin and metalloproteinase domain-containing protein 17 14513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113849&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 845855 252663380 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235537 CCOC(=O)Cc1csc(NC(=O)c2sc3nc4cc(C)ccc4cc3c2N)n1 InChI=1S/C20H18N4O3S2/c1-3-27-15(25)8-12-9-28-20(22-12)24-18(26)17-16(21)13-7-11-5-4-10(2)6-14(11)23-19(13)29-17/h4-7,9H,3,8,21H2,1-2H3,(H,22,24,26) DGVJQCOKXOACNG-UHFFFAOYSA-N 52442 2-[2-[(3-amino-7-methyl-thieno[2,3-b]quinoline-2-carbonyl)amino]thiazol-4-yl]acetic acid ethyl ester::2-[2-[[(3-amino-7-methyl-2-thieno[2,3-b]quinolinyl)-oxomethyl]amino]-4-thiazolyl]acetic acid ethyl ester::MLS000564527::SMR000172488::cid_3167478::ethyl 2-[2-[(3-amino-7-methylthieno[2,3-b]quinoline-2-carbonyl)amino]-1,3-thiazol-4-yl]acetate::ethyl 2-[2-[(3-azanyl-7-methyl-thieno[2,3-b]quinolin-2-yl)carbonylamino]-1,3-thiazol-4-yl]ethanoate::{2-[(3-Amino-7-methyl-thieno[2,3-b]quinoline-2-carbonyl)-amino]-thiazol-4-yl}-acetic acid ethyl ester Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52442 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52442&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3167478 252632585 ZINC03130576 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235538 Cc1ccc(Nc2nc(N)nc(CSc3nc4ccccc4s3)n2)cc1 InChI=1S/C18H16N6S2/c1-11-6-8-12(9-7-11)20-17-23-15(22-16(19)24-17)10-25-18-21-13-4-2-3-5-14(13)26-18/h2-9H,10H2,1H3,(H3,19,20,22,23,24) DIVSEVVHTAMUHI-UHFFFAOYSA-N 113850 6-(1,3-benzothiazol-2-ylsulfanylmethyl)-2-N-(4-methylphenyl)-1,3,5-triazine-2,4-diamine::6-(1,3-benzothiazol-2-ylsulfanylmethyl)-N2-(4-methylphenyl)-1,3,5-triazine-2,4-diamine::6-(Benzothiazol-2-ylsulfanylmethyl)-N-p-tolyl-[1,3,5]triazine-2,4-diamine::6-[(1,3-benzothiazol-2-ylthio)methyl]-N2-(4-methylphenyl)-1,3,5-triazine-2,4-diamine::MLS000551146::SMR000178238::[4-amino-6-[(1,3-benzothiazol-2-ylthio)methyl]-s-triazin-2-yl]-(p-tolyl)amine::cid_1076245 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113850&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1076245 252663381 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235539 Cc1cccc2cc(CN(Cc3ccco3)C(=O)Nc3cccc(c3)C#N)c(Cl)nc12 InChI=1S/C24H19ClN4O2/c1-16-5-2-7-18-12-19(23(25)28-22(16)18)14-29(15-21-9-4-10-31-21)24(30)27-20-8-3-6-17(11-20)13-26/h2-12H,14-15H2,1H3,(H,27,30) FSABWXNUKXBSCU-UHFFFAOYSA-N 77405 1-(2-Chloro-8-methyl-quinolin-3-ylmethyl)-3-(3-cyano-phenyl)-1-furan-2-ylmethyl-urea::1-[(2-chloranyl-8-methyl-quinolin-3-yl)methyl]-3-(3-cyanophenyl)-1-(furan-2-ylmethyl)urea::1-[(2-chloro-8-methyl-3-quinolinyl)methyl]-3-(3-cyanophenyl)-1-(2-furanylmethyl)urea::1-[(2-chloro-8-methyl-3-quinolyl)methyl]-3-(3-cyanophenyl)-1-(2-furfuryl)urea::1-[(2-chloro-8-methylquinolin-3-yl)methyl]-3-(3-cyanophenyl)-1-(furan-2-ylmethyl)urea::MLS000550816::SMR000173665::cid_1439943 Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=77405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=77405&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1439943 252654452 ZINC01339439 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235540 COc1ccc(cc1)S(=O)(=O)N1CCC(CC1)c1cc(n[nH]1)-c1cccc2ccccc12 InChI=1S/C25H25N3O3S/c1-31-20-9-11-21(12-10-20)32(29,30)28-15-13-19(14-16-28)24-17-25(27-26-24)23-8-4-6-18-5-2-3-7-22(18)23/h2-12,17,19H,13-16H2,1H3,(H,26,27) YRAFXAMCQLQPET-UHFFFAOYSA-N 113851 1-(4-methoxyphenyl)sulfonyl-4-(3-naphthalen-1-yl-1H-pyrazol-5-yl)piperidine::1-(4-methoxyphenyl)sulfonyl-4-[3-(1-naphthalenyl)-1H-pyrazol-5-yl]piperidine::1-(4-methoxyphenyl)sulfonyl-4-[3-(1-naphthyl)-1H-pyrazol-5-yl]piperidine::MLS000549331::SMR000168914::cid_1482149::methyl 4-({4-[5-(1-naphthyl)-1H-pyrazol-3-yl]piperidino}sulfonyl)phenyl ether Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113851&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1482149 252663382 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235541 Cc1cc(C)cc(NS(=O)(=O)c2ccc(Oc3ncc(cc3Cl)C(F)(F)F)cc2)c1 InChI=1S/C20H16ClF3N2O3S/c1-12-7-13(2)9-15(8-12)26-30(27,28)17-5-3-16(4-6-17)29-19-18(21)10-14(11-25-19)20(22,23)24/h3-11,26H,1-2H3 RIHPHIYYNOTTIG-UHFFFAOYSA-N 113852 4-[3-chloranyl-5-(trifluoromethyl)pyridin-2-yl]oxy-N-(3,5-dimethylphenyl)benzenesulfonamide::4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy-N-(3,5-dimethylphenyl)benzenesulfonamide::4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]-N-(3,5-dimethylphenyl)benzenesulfonamide::4-[[3-chloro-5-(trifluoromethyl)-2-pyridyl]oxy]-N-(3,5-dimethylphenyl)benzenesulfonamide::4-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}-N-(3,5-dimethylphenyl)benzenesulfonamide::MLS000328050::SMR000168565::cid_1471186 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113852&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1471186 252663383 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235542 Cc1ccc(cc1)S(=O)(=O)N1CCC(=O)N1 InChI=1S/C10H12N2O3S/c1-8-2-4-9(5-3-8)16(14,15)12-7-6-10(13)11-12/h2-5H,6-7H2,1H3,(H,11,13) GJOZCHSGDCFAAK-UHFFFAOYSA-N 113853 1-(4-methylphenyl)sulfonyl-3-pyrazolidinone::1-(4-methylphenyl)sulfonylpyrazolidin-3-one::1-[(4-methylphenyl)sulfonyl]tetrahydro-3H-pyrazol-3-one::1-tosylpyrazolidin-3-one::MLS000327887::SMR000168419::cid_1487856 Disintegrin and metalloproteinase domain-containing protein 17 69555 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113853 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113853&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1487856 252663384 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235543 C(C=CN=Nc1nc2ccccc2s1)c1ccccc1 InChI=1S/C16H13N3S/c1-2-7-13(8-3-1)9-6-12-17-19-16-18-14-10-4-5-11-15(14)20-16/h1-8,10-12H,9H2 RXKPCZQBQRSUIE-UHFFFAOYSA-N 113854 1,3-benzothiazol-2-yl-[(E)-[(E)-3-phenylprop-2-enylidene]amino]amine::3-phenylacrylaldehyde 1,3-benzothiazol-2-ylhydrazone::MLS000578815::N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]-1,3-benzothiazol-2-amine::SMR000186604::cid_6896527 Disintegrin and metalloproteinase domain-containing protein 17 69503 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113854 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113854&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899699 252663385 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235544 C\C(\C=C1/SC(=O)N(CC(=O)Nc2cccc(O)c2)C1=O)=C/c1ccccc1 InChI=1S/C21H18N2O4S/c1-14(10-15-6-3-2-4-7-15)11-18-20(26)23(21(27)28-18)13-19(25)22-16-8-5-9-17(24)12-16/h2-12,24H,13H2,1H3,(H,22,25)/b14-10+,18-11- HHQVEABLHVHPRA-RZTVDGLLSA-N 113855 2-[(5Z)-2,4-diketo-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]thiazolidin-3-yl]-N-(3-hydroxyphenyl)acetamide::MLS000574057::N-(3-hydroxyphenyl)-2-[(5Z)-5-[(E)-2-methyl-3-phenyl-prop-2-enylidene]-2,4-bis(oxidanylidene)-1,3-thiazolidin-3-yl]ethanamide::N-(3-hydroxyphenyl)-2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide::N-(3-hydroxyphenyl)-2-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-2,4-dioxo-3-thiazolidinyl]acetamide::N-(3-hydroxyphenyl)-2-[5-(2-methyl-3-phenyl-2-propen-1-ylidene)-2,4-dioxo-1,3-thiazolidin-3-yl]acetamide::SMR000208960::cid_1566253 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113855&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1566253 252663386 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235545 NS(=O)(=O)c1ccc(NCc2cc(Cl)ccc2OCc2ccccc2F)cc1 InChI=1S/C20H18ClFN2O3S/c21-16-5-10-20(27-13-14-3-1-2-4-19(14)22)15(11-16)12-24-17-6-8-18(9-7-17)28(23,25)26/h1-11,24H,12-13H2,(H2,23,25,26) BFRUNMADSKMALK-UHFFFAOYSA-N 113856 4-({5-chloro-2-[(2-fluorobenzyl)oxy]benzyl}amino)benzenesulfonamide::4-[[5-chloranyl-2-[(2-fluorophenyl)methoxy]phenyl]methylamino]benzenesulfonamide::4-[[5-chloro-2-(2-fluorobenzyl)oxy-benzyl]amino]benzenesulfonamide::4-[[5-chloro-2-[(2-fluorophenyl)methoxy]phenyl]methylamino]benzenesulfonamide::MLS000582625::SMR000200971::cid_979811 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113856&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 979811 252663387 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235546 CSc1nsc2nc(=O)c(\C=C3/C=Nc4ccccc34)c(N)n12 InChI=1S/C15H11N5OS2/c1-22-15-19-23-14-18-13(21)10(12(16)20(14)15)6-8-7-17-11-5-3-2-4-9(8)11/h2-7H,16H2,1H3/b8-6+ RXGFZJWVFWZDJZ-SOFGYWHQSA-N 52520 (6Z)-5-imino-6-(1H-indol-3-ylmethylene)-3-(methylthio)-5,6-dihydro-7H-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-amino-6-[(Z)-3-indolylidenemethyl]-3-(methylthio)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-amino-6-[(Z)-indol-3-ylidenemethyl]-3-(methylthio)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-amino-6-[(Z)-indol-3-ylidenemethyl]-3-methylsulfanyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::5-azanyl-6-[(Z)-indol-3-ylidenemethyl]-3-methylsulfanyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one::MLS000730583::SMR000308859::cid_5875181 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52520&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5875181 252632660 ZINC02992769 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235547 COc1ccccc1NC(=O)CN(c1ccc(cc1)C12CC3CC(CC(C3)C1)C2)S(C)(=O)=O InChI=1S/C26H32N2O4S/c1-32-24-6-4-3-5-23(24)27-25(29)17-28(33(2,30)31)22-9-7-21(8-10-22)26-14-18-11-19(15-26)13-20(12-18)16-26/h3-10,18-20H,11-17H2,1-2H3,(H,27,29) BEAFBYGJBLTDLK-UHFFFAOYSA-N 113857 2-[4-(1-adamantyl)-N-mesyl-anilino]-N-(2-methoxyphenyl)acetamide::2-[4-(1-adamantyl)-N-methylsulfonylanilino]-N-(2-methoxyphenyl)acetamide::2-[[4-(1-adamantyl)phenyl]-methylsulfonyl-amino]-N-(2-methoxyphenyl)ethanamide::MLS000582280::N~2~-[4-(1-adamantyl)phenyl]-N~1~-(2-methoxyphenyl)-N~2~-(methylsulfonyl)glycinamide::SMR000200818::cid_2966844 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113857 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113857&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2966844 252663388 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235548 COc1ccc(C=CC(=O)c2c(O)n(CCC3=CCCCC3)c(=O)[nH]c2=O)cc1OC InChI=1S/C23H26N2O6/c1-30-18-11-9-16(14-19(18)31-2)8-10-17(26)20-21(27)24-23(29)25(22(20)28)13-12-15-6-4-3-5-7-15/h6,8-11,14,28H,3-5,7,12-13H2,1-2H3,(H,24,27,29) PYBSSPMYRUPSBK-UHFFFAOYSA-N 52525 1-[2-(1-cyclohexenyl)ethyl]-5-[(E)-3-(3,4-dimethoxyphenyl)-1-oxoprop-2-enyl]-6-hydroxypyrimidine-2,4-dione::1-[2-(cyclohexen-1-yl)ethyl]-5-[(E)-3-(3,4-dimethoxyphenyl)acryloyl]-6-hydroxy-pyrimidine-2,4-quinone::1-[2-(cyclohexen-1-yl)ethyl]-5-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-6-hydroxypyrimidine-2,4-dione::1-[2-(cyclohexen-1-yl)ethyl]-5-[(E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]-6-oxidanyl-pyrimidine-2,4-dione::3-(2-Cyclohex-1-enyl-ethyl)-5-[(E)-3-(3,4-dimethoxy-phenyl)-acryloyl]-6-hydroxy-1H-pyrimidine-2,4-dione::MLS000331159::SMR000221147::cid_6220154 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52525&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54729244 252632665 ZINC01156362 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235549 COc1cc(CN=O)cc(Br)c1OCc1ccc(Cl)cc1 InChI=1S/C15H13BrClNO3/c1-20-14-7-11(8-18-19)6-13(16)15(14)21-9-10-2-4-12(17)5-3-10/h2-7H,8-9H2,1H3 NCQKPOVSYOKJNJ-UHFFFAOYSA-N 113858 (1E)-3-bromo-4-(4-chlorobenzyl)oxy-5-methoxy-benzaldoxime::(1E)-3-bromo-4-[(4-chlorophenyl)methoxy]-5-methoxybenzaldehyde oxime::(NE)-N-[[3-bromanyl-4-[(4-chlorophenyl)methoxy]-5-methoxy-phenyl]methylidene]hydroxylamine::(NE)-N-[[3-bromo-4-[(4-chlorophenyl)methoxy]-5-methoxyphenyl]methylidene]hydroxylamine::3-bromo-4-[(4-chlorobenzyl)oxy]-5-methoxybenzaldehyde oxime::MLS000575167::SMR000196401::cid_6898169 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113858 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113858&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899700 252663389 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235550 COc1ccc(NC(=S)Nc2cc(n[nH]2)-c2ccccc2)cc1Cl InChI=1S/C17H15ClN4OS/c1-23-15-8-7-12(9-13(15)18)19-17(24)20-16-10-14(21-22-16)11-5-3-2-4-6-11/h2-10H,1H3,(H3,19,20,21,22,24) KWHRVNJXXFGXLL-UHFFFAOYSA-N 113859 1-(3-chloranyl-4-methoxy-phenyl)-3-(5-phenyl-1H-pyrazol-3-yl)thiourea::1-(3-chloro-4-methoxy-phenyl)-3-(5-phenyl-1H-pyrazol-3-yl)thiourea::1-(3-chloro-4-methoxyphenyl)-3-(5-phenyl-1H-pyrazol-3-yl)thiourea::MLS000582339::N-(3-chloro-4-methoxyphenyl)-N'-(3-phenyl-1H-pyrazol-5-yl)thiourea::SMR000200879::cid_2223899 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113859 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113859&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2223899 252663390 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235551 Cc1cccc(NS(=O)(=O)c2cc(ccc2C)C(=O)Nc2ccccc2-c2ccccc2)c1C InChI=1S/C28H26N2O3S/c1-19-10-9-15-25(21(19)3)30-34(32,33)27-18-23(17-16-20(27)2)28(31)29-26-14-8-7-13-24(26)22-11-5-4-6-12-22/h4-18,30H,1-3H3,(H,29,31) ONJGCFWPRMOPJQ-UHFFFAOYSA-N 113860 3-[(2,3-dimethylphenyl)sulfamoyl]-4-methyl-N-(2-phenylphenyl)benzamide::MLS000582081::N-2-biphenylyl-3-{[(2,3-dimethylphenyl)amino]sulfonyl}-4-methylbenzamide::SMR000201299::cid_2229952 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113860&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2229952 252663391 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235552 COc1ccc(cc1)N(CC(O)Cn1c2ccccc2c2ccccc12)S(=O)(=O)c1ccccc1 InChI=1S/C28H26N2O4S/c1-34-23-17-15-21(16-18-23)30(35(32,33)24-9-3-2-4-10-24)20-22(31)19-29-27-13-7-5-11-25(27)26-12-6-8-14-28(26)29/h2-18,22,31H,19-20H2,1H3 RVKMFYITESTEIC-UHFFFAOYSA-N 113861 MLS000574276::N-(3-carbazol-9-yl-2-hydroxy-propyl)-N-(4-methoxyphenyl)benzenesulfonamide::N-(3-carbazol-9-yl-2-hydroxypropyl)-N-(4-methoxyphenyl)benzenesulfonamide::N-(3-carbazol-9-yl-2-oxidanyl-propyl)-N-(4-methoxyphenyl)benzenesulfonamide::N-[3-(9-carbazolyl)-2-hydroxypropyl]-N-(4-methoxyphenyl)benzenesulfonamide::N-[3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(4-methoxyphenyl)benzenesulfonamide::SMR000195867::cid_2908002 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113861 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113861&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2908002 252663392 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235553 CSc1cccc(NC(=O)\C=C\c2ccc(Cl)cc2)c1 InChI=1S/C16H14ClNOS/c1-20-15-4-2-3-14(11-15)18-16(19)10-7-12-5-8-13(17)9-6-12/h2-11H,1H3,(H,18,19)/b10-7+ KNXMFRKDKCMOPU-JXMROGBWSA-N 113862 (E)-3-(4-chlorophenyl)-N-(3-methylsulfanylphenyl)prop-2-enamide::(E)-3-(4-chlorophenyl)-N-[3-(methylthio)phenyl]-2-propenamide::(E)-3-(4-chlorophenyl)-N-[3-(methylthio)phenyl]acrylamide::MLS000577339::SMR000197449::cid_892765 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113862&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 892765 252663393 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235554 Cc1cc(\C=C(\C#N)c2nc3ccccc3[nH]2)c(C)n1-c1ccccc1C(O)=O InChI=1S/C23H18N4O2/c1-14-11-16(15(2)27(14)21-10-6-3-7-18(21)23(28)29)12-17(13-24)22-25-19-8-4-5-9-20(19)26-22/h3-12H,1-2H3,(H,25,26)(H,28,29)/b17-12- DRRLXWOFTBQDAV-ATVHPVEESA-N 52558 2-[3-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyano-ethenyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid::2-[3-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyano-vinyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid::2-[3-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2,5-dimethyl-1-pyrrolyl]benzoic acid::2-[3-[(Z)-2-(1H-benzimidazol-2-yl)-2-cyanoethenyl]-2,5-dimethylpyrrol-1-yl]benzoic acid::2-{3-[2-(1H-benzimidazol-2-yl)-2-cyanovinyl]-2,5-dimethyl-1H-pyrrol-1-yl}benzoic acid::MLS000693391::SMR000299928::cid_5739378 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52558 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52558&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5739378 252632698 ZINC02982442 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235555 Cc1cc(C=C2C(=O)NC(=O)N(C2=O)c2ccc(F)cc2)c(C)n1-c1cccc(c1)C(O)=O InChI=1S/C24H18FN3O5/c1-13-10-16(14(2)27(13)19-5-3-4-15(11-19)23(31)32)12-20-21(29)26-24(33)28(22(20)30)18-8-6-17(25)7-9-18/h3-12H,1-2H3,(H,31,32)(H,26,29,33) AMOUMSPROQNJSP-UHFFFAOYSA-N 52570 3-[3-[(E)-[1-(4-fluorophenyl)-2,4,6-triketo-hexahydropyrimidin-5-ylidene]methyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid::3-[3-[(E)-[1-(4-fluorophenyl)-2,4,6-trioxo-1,3-diazinan-5-ylidene]methyl]-2,5-dimethyl-1-pyrrolyl]benzoic acid::3-[3-[(E)-[1-(4-fluorophenyl)-2,4,6-trioxo-1,3-diazinan-5-ylidene]methyl]-2,5-dimethylpyrrol-1-yl]benzoic acid::3-[3-[(E)-[1-(4-fluorophenyl)-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid::MLS000714044::SMR000273524::cid_1727782 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52570 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52570&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1727782 252632710 ZINC15987961 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235556 Clc1nc(N=NCc2ccccc2)c(Cl)c(Cl)c1C#N InChI=1S/C13H7Cl3N4/c14-10-9(6-17)12(16)19-13(11(10)15)20-18-7-8-4-2-1-3-5-8/h1-5H,7H2 CPYXFROYURZIQU-UHFFFAOYSA-N 113863 2,4,5-trichloro-6-[(2E)-2-(phenylmethylene)hydrazinyl]-3-pyridinecarbonitrile::2,4,5-tris(chloranyl)-6-[(2E)-2-(phenylmethylidene)hydrazinyl]pyridine-3-carbonitrile::6-(2-benzylidenehydrazino)-2,4,5-trichloronicotinonitrile::6-[(2E)-2-benzylidenehydrazinyl]-2,4,5-trichloropyridine-3-carbonitrile::6-[(N'E)-N'-benzalhydrazino]-2,4,5-trichloro-nicotinonitrile::MLS000595048::SMR000185242::cid_5331860 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113863&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899701 252663394 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235557 O=C(CN(Cc1cccs1)S(=O)(=O)c1ccc(cc1)S(=O)(=O)NC1CCCCC1)Nc1ccccc1 InChI=1S/C25H29N3O5S3/c29-25(26-20-8-3-1-4-9-20)19-28(18-22-12-7-17-34-22)36(32,33)24-15-13-23(14-16-24)35(30,31)27-21-10-5-2-6-11-21/h1,3-4,7-9,12-17,21,27H,2,5-6,10-11,18-19H2,(H,26,29) MFEDJQGOERVAHD-UHFFFAOYSA-N 113864 2-[(4-Cyclohexylsulfamoyl-benzenesulfonyl)-thiophen-2-ylmethyl-amino]-N-phenyl-acetamide::2-[[4-(cyclohexylsulfamoyl)phenyl]sulfonyl-(2-thenyl)amino]-N-phenyl-acetamide::2-[[4-(cyclohexylsulfamoyl)phenyl]sulfonyl-(thiophen-2-ylmethyl)amino]-N-phenyl-ethanamide::2-[[4-(cyclohexylsulfamoyl)phenyl]sulfonyl-(thiophen-2-ylmethyl)amino]-N-phenylacetamide::MLS000548357::SMR000171048::cid_3202196 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113864 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113864&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3202196 252663395 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235558 COc1ccccc1NC(=S)NN=Cc1c[nH]c2ccc(cc12)S(=O)(=O)N1CCCCC1 InChI=1S/C22H25N5O3S2/c1-30-21-8-4-3-7-20(21)25-22(31)26-24-15-16-14-23-19-10-9-17(13-18(16)19)32(28,29)27-11-5-2-6-12-27/h3-4,7-10,13-15,23H,2,5-6,11-12H2,1H3,(H2,25,26,31)/b24-15+ VWSDHWLEPIAZBT-BUVRLJJBSA-N 84075 1-(2-methoxyphenyl)-3-[[(Z)-(5-piperidin-1-ylsulfonylindol-3-ylidene)methyl]amino]thiourea::1-(2-methoxyphenyl)-3-[[(Z)-(5-piperidinosulfonylindol-3-ylidene)methyl]amino]thiourea::1-(2-methoxyphenyl)-3-[[(Z)-[5-(1-piperidinylsulfonyl)-3-indolylidene]methyl]amino]thiourea::MLS-0454628.0002::cid_12004466 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=84075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=84075&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12004466 252659239 ZINC15974337 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235559 Cc1ccc(cc1)C(=O)C1C(C2CSCN2[C@@]11C(=O)Nc2ccc(C)cc12)c1cccc(c1)[N+]([O-])=O InChI=1S/C28H25N3O4S/c1-16-6-9-18(10-7-16)26(32)25-24(19-4-3-5-20(13-19)31(34)35)23-14-36-15-30(23)28(25)21-12-17(2)8-11-22(21)29-27(28)33/h3-13,23-25H,14-15H2,1-2H3,(H,29,33)/t23?,24?,25?,28-/m1/s1 DCAZCKMMEAPQGQ-YKLXMYAUSA-N 70704 (3S)-5-methyl-6'-(4-methylbenzoyl)-7'-(3-nitrophenyl)spiro[1H-indole-3,5'-3,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazole]-2-one::(3S)-5-methyl-6'-(4-methylphenyl)carbonyl-7'-(3-nitrophenyl)spiro[1H-indole-3,5'-3,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c][1,3]thiazole]-2-one::(3S)-5-methyl-6'-[(4-methylphenyl)-oxomethyl]-7'-(3-nitrophenyl)-2-spiro[1H-indole-3,5'-3,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c]thiazole]one::(5S)-5'-methyl-7-(3-nitrophenyl)-6-p-toluoyl-spiro[3,6,7,7a-tetrahydro-1H-pyrrolo[1,2-c]thiazole-5,3'-indoline]-2'-one::MLS000332133::SMR000221616::cid_12004476 Disintegrin and metalloproteinase domain-containing protein 17 69507 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=70704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=70704&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12004476 252648639 ZINC36316834 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235560 NC(=O)C1CCN(CC1)C(=O)c1ccc2c3nc4ccccc4n3c(SCC#N)nc2c1 InChI=1S/C23H20N6O2S/c24-9-12-32-23-27-18-13-15(22(31)28-10-7-14(8-11-28)20(25)30)5-6-16(18)21-26-17-3-1-2-4-19(17)29(21)23/h1-6,13-14H,7-8,10-12H2,(H2,25,30) MYUCPCJDLCLXDA-UHFFFAOYSA-N 44650 1-({6-[(cyanomethyl)thio]benzimidazo[1,2-c]quinazolin-3-yl}carbonyl)piperidine-4-carboxamide::1-[6-(cyanomethylsulfanyl)benzimidazolo[1,2-c]quinazolin-3-yl]carbonylpiperidine-4-carboxamide::1-[6-(cyanomethylsulfanyl)benzimidazolo[1,2-c]quinazoline-3-carbonyl]piperidine-4-carboxamide::1-[6-(cyanomethylthio)benzimidazolo[1,2-c]quinazoline-3-carbonyl]isonipecotamide::1-[[6-(cyanomethylthio)-3-benzimidazolo[1,2-c]quinazolinyl]-oxomethyl]-4-piperidinecarboxamide::CHEMBL1501213::MLS000095230::SMR000030784::cid_3240564 Disintegrin and metalloproteinase domain-containing protein 17 69555 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=44650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=44650&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3240564 252625256 CHEMBL1501213 ZINC00495777 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235561 Cc1cccc(OCCNC(=O)c2cccc(Oc3ccc(cc3[N+]([O-])=O)C(F)(F)F)c2)c1 InChI=1S/C23H19F3N2O5/c1-15-4-2-6-18(12-15)32-11-10-27-22(29)16-5-3-7-19(13-16)33-21-9-8-17(23(24,25)26)14-20(21)28(30)31/h2-9,12-14H,10-11H2,1H3,(H,27,29) CLIBKXLUTURPLO-UHFFFAOYSA-N 113865 MLS000573853::N-[2-(3-methylphenoxy)ethyl]-3-[2-nitro-4-(trifluoromethyl)phenoxy]benzamide::SMR000195442::cid_2178268 Disintegrin and metalloproteinase domain-containing protein 17 69507 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113865 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113865&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2178268 252663396 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235562 OC(COCC(F)(F)C(F)(F)C(F)(F)C(F)F)Cn1c2ccccc2c2ccccc12 InChI=1S/C20H17F8NO2/c21-17(22)19(25,26)20(27,28)18(23,24)11-31-10-12(30)9-29-15-7-3-1-5-13(15)14-6-2-4-8-16(14)29/h1-8,12,17,30H,9-11H2 BKQACYCBLLJVJL-UHFFFAOYSA-N 67995 1-(9-carbazolyl)-3-(2,2,3,3,4,4,5,5-octafluoropentoxy)-2-propanol::1-Carbazol-9-yl-3-(2,2,3,3,4,4,5,5-octafluoro-pentyloxy)-propan-2-ol::1-carbazol-9-yl-3-(2,2,3,3,4,4,5,5-octafluoropentoxy)propan-2-ol::1-carbazol-9-yl-3-[2,2,3,3,4,4,5,5-octakis(fluoranyl)pentoxy]propan-2-ol::MLS000559736::SMR000176805::cid_3129563 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67995&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3129563 252646274 ZINC02274237 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235563 Nc1nc(c(N=Nc2ccccc2Cl)s1)-c1ccccc1 InChI=1S/C15H11ClN4S/c16-11-8-4-5-9-12(11)19-20-14-13(18-15(17)21-14)10-6-2-1-3-7-10/h1-9H,(H2,17,18) PCNJSARSIUDICD-UHFFFAOYSA-N 65162 (2-chlorophenyl)-[(Z)-(2-imino-4-phenyl-3-thiazolin-5-ylidene)amino]amine;hydrobromide::2-chloro-N-[(Z)-(2-imino-4-phenyl-1,3-thiazol-5-ylidene)amino]aniline;hydrobromide::2-chloro-N-[(Z)-(2-imino-4-phenyl-5-thiazolylidene)amino]aniline;hydrobromide::5-(2-Chloro-phenylazo)-4-phenyl-thiazol-2-ylamine::MLS000561368::N-[(Z)-(2-azanylidene-4-phenyl-1,3-thiazol-5-ylidene)amino]-2-chloranyl-aniline;hydrobromide::SMR000175147::cid_12004712 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65162&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6411000 252643942 ZINC05773966 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235564 O=C(NCC1CCCO1)C(N(Cc1ccccc1)C(=O)c1ccc([nH]1)-c1ccccc1)c1cccs1 InChI=1S/C29H29N3O3S/c33-28(30-19-23-13-7-17-35-23)27(26-14-8-18-36-26)32(20-21-9-3-1-4-10-21)29(34)25-16-15-24(31-25)22-11-5-2-6-12-22/h1-6,8-12,14-16,18,23,27,31H,7,13,17,19-20H2,(H,30,33) JARWWLDFLXGFFO-UHFFFAOYSA-N 113866 5-Phenyl-1H-pyrrole-2-carboxylic acid benzyl-{[(tetrahydro-furan-2-ylmethyl)-carbamoyl]-thiophen-2-yl-methyl}-amide::MLS000564496::N-[2-oxidanylidene-2-(oxolan-2-ylmethylamino)-1-thiophen-2-yl-ethyl]-5-phenyl-N-(phenylmethyl)-1H-pyrrole-2-carboxamide::N-[2-oxo-2-(2-oxolanylmethylamino)-1-thiophen-2-ylethyl]-5-phenyl-N-(phenylmethyl)-1H-pyrrole-2-carboxamide::N-benzyl-N-[2-keto-2-(tetrahydrofurfurylamino)-1-(2-thienyl)ethyl]-5-phenyl-1H-pyrrole-2-carboxamide::N-benzyl-N-[2-oxo-2-(oxolan-2-ylmethylamino)-1-thiophen-2-ylethyl]-5-phenyl-1H-pyrrole-2-carboxamide::SMR000172637::cid_3174569 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113866 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113866&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3174569 252663397 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235565 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1nnc(SCc2ccccc2Cl)o1 InChI=1S/C22H18ClN3O3S2/c1-15-6-12-19(13-7-15)31(27,28)26-18-10-8-16(9-11-18)21-24-25-22(29-21)30-14-17-4-2-3-5-20(17)23/h2-13,26H,14H2,1H3 WMMHPILYPHGNKR-UHFFFAOYSA-N 113867 MLS000553513::N-[4-[5-[(2-chlorobenzyl)thio]-1,3,4-oxadiazol-2-yl]phenyl]-4-methyl-benzenesulfonamide::N-[4-[5-[(2-chlorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]phenyl]-4-methyl-benzenesulfonamide::N-[4-[5-[(2-chlorophenyl)methylsulfanyl]-1,3,4-oxadiazol-2-yl]phenyl]-4-methylbenzenesulfonamide::N-[4-[5-[(2-chlorophenyl)methylthio]-1,3,4-oxadiazol-2-yl]phenyl]-4-methylbenzenesulfonamide::N-{4-[5-(2-Chloro-benzylsulfanyl)-[1,3,4]oxadiazol-2-yl]-phenyl}-4-methyl-benzenesulfonamide::SMR000170932::cid_1150498 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113867 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113867&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1150498 252663398 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235566 CCC(=O)N(Cc1ccco1)c1nc(C(=O)Nc2ccc(Cl)cc2)c(C)s1 InChI=1S/C19H18ClN3O3S/c1-3-16(24)23(11-15-5-4-10-26-15)19-22-17(12(2)27-19)18(25)21-14-8-6-13(20)7-9-14/h4-10H,3,11H2,1-2H3,(H,21,25) STQDZVUOFAEBNS-UHFFFAOYSA-N 113868 2-(Furan-2-ylmethyl-propionyl-amino)-5-methyl-thiazole-4-carboxylic acid (4-chloro-phenyl)-amide::MLS000567551::N-(4-chlorophenyl)-2-[2-furanylmethyl(1-oxopropyl)amino]-5-methyl-4-thiazolecarboxamide::N-(4-chlorophenyl)-2-[2-furfuryl(propionyl)amino]-5-methyl-thiazole-4-carboxamide::N-(4-chlorophenyl)-2-[furan-2-ylmethyl(propanoyl)amino]-5-methyl-1,3-thiazole-4-carboxamide::SMR000173021::cid_1455394 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113868 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113868&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1455394 252663399 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235567 CCOC(=O)c1ccc(cc1)N1C(c2c(n[nH]c2C1=O)-c1ccco1)c1ccc(cc1)[N+]([O-])=O InChI=1S/C24H18N4O6/c1-2-33-24(30)15-7-9-16(10-8-15)27-22(14-5-11-17(12-6-14)28(31)32)19-20(18-4-3-13-34-18)25-26-21(19)23(27)29/h3-13,22H,2H2,1H3,(H,25,26) NSEKTJBXFWIVMK-UHFFFAOYSA-N 70772 4-[3-(2-furanyl)-4-(4-nitrophenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid ethyl ester::4-[3-(2-furyl)-6-keto-4-(4-nitrophenyl)-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoic acid ethyl ester::MLS000583189::SMR000206375::cid_12005112::ethyl 4-[3-(2-furyl)-4-(4-nitrophenyl)-6-oxo-4,6-dihydropyrrolo[3,4-c]pyrazol-5(1H)-yl]benzoate::ethyl 4-[3-(furan-2-yl)-4-(4-nitrophenyl)-6-oxidanylidene-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoate::ethyl 4-[3-(furan-2-yl)-4-(4-nitrophenyl)-6-oxo-2,4-dihydropyrrolo[3,4-c]pyrazol-5-yl]benzoate Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=70772 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=70772&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12005112 252648659 ZINC15974175 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235568 Clc1ccc(NC(CNS(=O)(=O)c2ccc(Cl)cc2)c2ccccc2)cc1 InChI=1S/C20H18Cl2N2O2S/c21-16-6-10-18(11-7-16)24-20(15-4-2-1-3-5-15)14-23-27(25,26)19-12-8-17(22)9-13-19/h1-13,20,23-24H,14H2 AQTWXECSKSZRRN-UHFFFAOYSA-N 68014 4-chloranyl-N-[2-[(4-chlorophenyl)amino]-2-phenyl-ethyl]benzenesulfonamide::4-chloro-N-[2-(4-chloroanilino)-2-phenyl-ethyl]benzenesulfonamide::4-chloro-N-[2-(4-chloroanilino)-2-phenylethyl]benzenesulfonamide::4-chloro-N-{2-[(4-chlorophenyl)amino]-2-phenylethyl}benzenesulfonamide::MLS000586486::SMR000207865::cid_4082378 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68014&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4082378 252646293 ZINC02907957 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235569 Clc1ccc(NC(CNS(=O)(=O)c2ccccc2)c2ccccc2)cc1 InChI=1S/C20H19ClN2O2S/c21-17-11-13-18(14-12-17)23-20(16-7-3-1-4-8-16)15-22-26(24,25)19-9-5-2-6-10-19/h1-14,20,22-23H,15H2 SSYJOGFDCBRAOG-UHFFFAOYSA-N 113869 MLS000586485::N-[2-(4-chloroanilino)-2-phenyl-ethyl]benzenesulfonamide::N-[2-(4-chloroanilino)-2-phenylethyl]benzenesulfonamide::N-[2-[(4-chlorophenyl)amino]-2-phenyl-ethyl]benzenesulfonamide::N-{2-[(4-chlorophenyl)amino]-2-phenylethyl}benzenesulfonamide::SMR000207864::cid_4076954 Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113869 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113869&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4076954 252663400 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235570 COc1ccc(NC(C)C(=O)N\N=C\c2ccccc2OCc2cccc(Br)c2)cc1 InChI=1S/C24H24BrN3O3/c1-17(27-21-10-12-22(30-2)13-11-21)24(29)28-26-15-19-7-3-4-9-23(19)31-16-18-6-5-8-20(25)14-18/h3-15,17,27H,16H2,1-2H3,(H,28,29)/b26-15+ QMOIYTIUVMMHAZ-CVKSISIWSA-N 113870 MLS000585031::N-[(E)-[2-(3-bromobenzyl)oxybenzylidene]amino]-2-(p-anisidino)propionamide::N-[(E)-[2-[(3-bromophenyl)methoxy]phenyl]methylideneamino]-2-(4-methoxyanilino)propanamide::N-[(E)-[2-[(3-bromophenyl)methoxy]phenyl]methylideneamino]-2-[(4-methoxyphenyl)amino]propanamide::SMR000203794::cid_56642833 Disintegrin and metalloproteinase domain-containing protein 17 69490 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113870 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113870&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56642833 252663401 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235571 Fc1ccc(cc1C(=O)Nc1cccc(Cl)c1)S(=O)(=O)NCCc1ccc(Cl)cc1 InChI=1S/C21H17Cl2FN2O3S/c22-15-6-4-14(5-7-15)10-11-25-30(28,29)18-8-9-20(24)19(13-18)21(27)26-17-3-1-2-16(23)12-17/h1-9,12-13,25H,10-11H2,(H,26,27) WTICICLYJYFKSZ-UHFFFAOYSA-N 72230 MLS000586574::N-(3-chlorophenyl)-5-({[2-(4-chlorophenyl)ethyl]amino}sulfonyl)-2-fluorobenzamide::N-(3-chlorophenyl)-5-[2-(4-chlorophenyl)ethylsulfamoyl]-2-fluoranyl-benzamide::N-(3-chlorophenyl)-5-[2-(4-chlorophenyl)ethylsulfamoyl]-2-fluoro-benzamide::N-(3-chlorophenyl)-5-[2-(4-chlorophenyl)ethylsulfamoyl]-2-fluorobenzamide::SMR000207953::cid_3354885 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72230&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3354885 252649493 ZINC03023819 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235572 CNC(=S)NN=Cc1cn(CCOc2ccc(OC)cc2)c2ccccc12 InChI=1S/C20H22N4O2S/c1-21-20(27)23-22-13-15-14-24(19-6-4-3-5-18(15)19)11-12-26-17-9-7-16(25-2)8-10-17/h3-10,13-14H,11-12H2,1-2H3,(H2,21,23,27) RWGCAWBFUPGYEE-UHFFFAOYSA-N 113871 1-[(E)-[1-[2-(4-methoxyphenoxy)ethyl]-3-indolyl]methylideneamino]-3-methylthiourea::1-[(E)-[1-[2-(4-methoxyphenoxy)ethyl]indol-3-yl]methyleneamino]-3-methyl-thiourea::1-[(E)-[1-[2-(4-methoxyphenoxy)ethyl]indol-3-yl]methylideneamino]-3-methyl-thiourea::1-[(E)-[1-[2-(4-methoxyphenoxy)ethyl]indol-3-yl]methylideneamino]-3-methylthiourea::MLS000591014::SMR000217742::cid_6865382 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113871 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113871&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6865382 252663402 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235573 CCCOc1ccc(NC(=O)CC2N(Cc3cccs3)C(=S)N(Cc3ccccc3)C2=O)cc1 InChI=1S/C26H27N3O3S2/c1-2-14-32-21-12-10-20(11-13-21)27-24(30)16-23-25(31)29(17-19-7-4-3-5-8-19)26(33)28(23)18-22-9-6-15-34-22/h3-13,15,23H,2,14,16-18H2,1H3,(H,27,30) KALYRSAVKNVWHX-UHFFFAOYSA-N 113872 2-(1-Benzyl-5-oxo-3-thiophen-2-ylmethyl-2-thioxo-imidazolidin-4-yl)-N-(4-propoxy-phenyl)-acetamide::2-[1-benzyl-5-keto-3-(2-thenyl)-2-thioxo-imidazolidin-4-yl]-N-(4-propoxyphenyl)acetamide::2-[1-benzyl-5-oxo-2-sulfanylidene-3-(thiophen-2-ylmethyl)imidazolidin-4-yl]-N-(4-propoxyphenyl)acetamide::2-[5-oxidanylidene-1-(phenylmethyl)-2-sulfanylidene-3-(thiophen-2-ylmethyl)imidazolidin-4-yl]-N-(4-propoxyphenyl)ethanamide::2-[5-oxo-1-(phenylmethyl)-2-sulfanylidene-3-(thiophen-2-ylmethyl)-4-imidazolidinyl]-N-(4-propoxyphenyl)acetamide::MLS000590061::SMR000219277::cid_3828582 Disintegrin and metalloproteinase domain-containing protein 17 69555 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113872 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113872&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3828582 252663403 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235574 Clc1ccc(C(=O)N\C(=C/c2ccc3OCOc3c2)C(=O)NCCc2nc3ccccc3[nH]2)c(Cl)c1 InChI=1S/C26H20Cl2N4O4/c27-16-6-7-17(18(28)13-16)25(33)32-21(11-15-5-8-22-23(12-15)36-14-35-22)26(34)29-10-9-24-30-19-3-1-2-4-20(19)31-24/h1-8,11-13H,9-10,14H2,(H,29,34)(H,30,31)(H,32,33)/b21-11- LLWHYTJSWHHFHS-NHDPSOOVSA-N 113873 MLS000331699::N-[(Z)-1-[2-(1H-benzimidazol-2-yl)ethylcarbamoyl]-2-(1,3-benzodioxol-5-yl)vinyl]-2,4-dichloro-benzamide::N-[(Z)-3-[2-(1H-benzimidazol-2-yl)ethylamino]-1-(1,3-benzodioxol-5-yl)-3-oxidanylidene-prop-1-en-2-yl]-2,4-bis(chloranyl)benzamide::N-[(Z)-3-[2-(1H-benzimidazol-2-yl)ethylamino]-1-(1,3-benzodioxol-5-yl)-3-oxoprop-1-en-2-yl]-2,4-dichlorobenzamide::N-{(Z)-2-Benzo[1,3]dioxol-5-yl-1-[2-(1H-benzoimidazol-2-yl)-ethylcarbamoyl]-vinyl}-2,4-dichloro-benzamide::SMR000220754::cid_2003578 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113873&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2003578 252663404 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235575 Oc1ccc(cc1)C1CC(=NN1C(=O)c1cccs1)c1ccccc1 InChI=1S/C20H16N2O2S/c23-16-10-8-15(9-11-16)18-13-17(14-5-2-1-3-6-14)21-22(18)20(24)19-7-4-12-25-19/h1-12,18,23H,13H2 AGCXWRBNCJJTAU-UHFFFAOYSA-N 113874 MLS000697273::SMR000238003::[3-(4-hydroxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-thiophen-2-yl-methanone::[3-(4-hydroxyphenyl)-5-phenyl-3,4-dihydropyrazol-2-yl]-thiophen-2-ylmethanone::[5-(4-hydroxyphenyl)-3-phenyl-2-pyrazolin-1-yl]-(2-thienyl)methanone::cid_12005820 Disintegrin and metalloproteinase domain-containing protein 17 69507 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113874 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113874&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12005820 252663405 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235576 Cc1ccc(cc1)S(=O)(=O)Nc1ccc(cc1)-c1csc(n1)-c1ccccc1 InChI=1S/C22H18N2O2S2/c1-16-7-13-20(14-8-16)28(25,26)24-19-11-9-17(10-12-19)21-15-27-22(23-21)18-5-3-2-4-6-18/h2-15,24H,1H3 HZFLKGBTYDTOFI-UHFFFAOYSA-N 113875 4-methyl-N-[4-(2-phenyl-1,3-thiazol-4-yl)phenyl]benzenesulfonamide::4-methyl-N-[4-(2-phenyl-4-thiazolyl)phenyl]benzenesulfonamide::4-methyl-N-[4-(2-phenylthiazol-4-yl)phenyl]benzenesulfonamide::MLS000697223::SMR000237709::cid_2896660 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113875 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113875&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2896660 252663406 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235577 Cc1ccc(NCC(=O)NN=Cc2ccc(cc2)C(O)=O)cc1 InChI=1S/C17H17N3O3/c1-12-2-8-15(9-3-12)18-11-16(21)20-19-10-13-4-6-14(7-5-13)17(22)23/h2-10,18H,11H2,1H3,(H,20,21)(H,22,23) CHWGXLXOPNVABR-UHFFFAOYSA-N 52699 4-[[2-[(4-methylphenyl)amino]ethanoylhydrazinylidene]methyl]benzoic acid::4-[[[2-(4-methylanilino)-1-oxoethyl]hydrazinylidene]methyl]benzoic acid::4-[[[2-(4-methylanilino)acetyl]hydrazinylidene]methyl]benzoic acid::4-[[[2-(p-toluidino)acetyl]hydrazono]methyl]benzoic acid::MLS000714364::SMR000274344::cid_833787 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52699&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 833787 252632837 ZINC03022264 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235578 CSc1cccc(NC(=O)CCCOc2ccc(Cl)cc2C)c1 InChI=1S/C18H20ClNO2S/c1-13-11-14(19)8-9-17(13)22-10-4-7-18(21)20-15-5-3-6-16(12-15)23-2/h3,5-6,8-9,11-12H,4,7,10H2,1-2H3,(H,20,21) QYUAQMKYPOOVBA-UHFFFAOYSA-N 113876 4-(4-chloranyl-2-methyl-phenoxy)-N-(3-methylsulfanylphenyl)butanamide::4-(4-chloro-2-methyl-phenoxy)-N-[3-(methylthio)phenyl]butyramide::4-(4-chloro-2-methylphenoxy)-N-(3-methylsulfanylphenyl)butanamide::4-(4-chloro-2-methylphenoxy)-N-[3-(methylthio)phenyl]butanamide::MLS000334052::SMR000248810::cid_2111621 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113876 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113876&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2111621 252663407 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235579 Clc1ccccc1C(=O)N\N=C\c1cn(nc1-c1ccccc1)-c1cccs1 InChI=1S/C21H15ClN4OS/c22-18-10-5-4-9-17(18)21(27)24-23-13-16-14-26(19-11-6-12-28-19)25-20(16)15-7-2-1-3-8-15/h1-14H,(H,24,27)/b23-13+ PVTUMZHWOKQGQX-YDZHTSKRSA-N 113877 2-chloranyl-N-[(E)-(3-phenyl-1-thiophen-2-yl-pyrazol-4-yl)methylideneamino]benzamide::2-chloro-N-[(E)-(3-phenyl-1-thiophen-2-yl-4-pyrazolyl)methylideneamino]benzamide::2-chloro-N-[(E)-(3-phenyl-1-thiophen-2-ylpyrazol-4-yl)methylideneamino]benzamide::2-chloro-N-[(E)-[3-phenyl-1-(2-thienyl)pyrazol-4-yl]methyleneamino]benzamide::MLS000390836::SMR000259874::cid_6901676 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113877 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113877&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6901676 252663408 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235580 COc1cc(OC)c(cc1Cl)N(C)S(=O)(=O)c1cccc(c1)C(=O)OCC(=O)c1c[nH]c2ccccc12 InChI=1S/C26H23ClN2O7S/c1-29(22-12-20(27)24(34-2)13-25(22)35-3)37(32,33)17-8-6-7-16(11-17)26(31)36-15-23(30)19-14-28-21-10-5-4-9-18(19)21/h4-14,28H,15H2,1-3H3 CIEGLKTXEYBKIC-UHFFFAOYSA-N 113878 3-[(5-chloro-2,4-dimethoxy-phenyl)-methyl-sulfamoyl]benzoic acid [2-(1H-indol-3-yl)-2-keto-ethyl] ester::3-[(5-chloro-2,4-dimethoxyphenyl)-methylsulfamoyl]benzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester::MLS000417291::SMR000242527::[2-(1H-indol-3-yl)-2-oxidanylidene-ethyl] 3-[(5-chloranyl-2,4-dimethoxy-phenyl)-methyl-sulfamoyl]benzoate::[2-(1H-indol-3-yl)-2-oxoethyl] 3-[(5-chloro-2,4-dimethoxyphenyl)-methylsulfamoyl]benzoate::cid_2463081 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113878 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113878&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2463081 252663409 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235581 CN(C)c1ccc(cc1)C(CNS(=O)(=O)c1ccc(F)c(F)c1)c1c[nH]c2ccccc12 InChI=1S/C24H23F2N3O2S/c1-29(2)17-9-7-16(8-10-17)20(21-14-27-24-6-4-3-5-19(21)24)15-28-32(30,31)18-11-12-22(25)23(26)13-18/h3-14,20,27-28H,15H2,1-2H3 OMRUCSXLPQAINA-UHFFFAOYSA-N 68039 MLS000417348::N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]-3,4-bis(fluoranyl)benzenesulfonamide::N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]-3,4-difluoro-benzenesulfonamide::N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]-3,4-difluorobenzenesulfonamide::SMR000242503::cid_3993080 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68039&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3993080 252646318 ZINC03294033 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235582 Clc1ccc(cc1)-n1nc2c(cc1=O)[nH][nH]c2=O InChI=1S/C11H7ClN4O2/c12-6-1-3-7(4-2-6)16-9(17)5-8-10(15-16)11(18)14-13-8/h1-5,13H,(H,14,18) BVWNEDJLGPEOJI-UHFFFAOYSA-N 52725 5-(4-chlorophenyl)-1,2-dihydropyrazolo[4,3-c]pyridazine-3,6-dione::5-(4-chlorophenyl)-1,2-dihydropyrazolo[4,3-c]pyridazine-3,6-quinone::5-(4-chlorophenyl)-3-hydroxy-1,5-dihydro-6H-pyrazolo[4,3-c]pyridazin-6-one::MLS000755380::SMR000337771::cid_1475762 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52725&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1475762 252632863 ZINC08774495 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235583 [O-][N+](=O)c1ccc(=O)[c-](C[NH+]=Nc2ccccn2)c1 InChI=1S/C12H9N4O3/c17-11-5-4-10(16(18)19)7-9(11)8-14-15-12-3-1-2-6-13-12/h1-7H,8H2/q-1/p+1 BKJACUSVOHMWAP-UHFFFAOYSA-O 65996 (6E)-4-nitro-6-[(2-pyridin-2-ylhydrazinyl)methylidene]cyclohexa-2,4-dien-1-one::(6E)-4-nitro-6-[(2-pyridinylhydrazo)methylidene]-1-cyclohexa-2,4-dienone::(6E)-4-nitro-6-[[N'-(2-pyridyl)hydrazino]methylene]cyclohexa-2,4-dien-1-one::2-hydroxy-5-nitrobenzaldehyde pyridin-2-ylhydrazone::MLS000585015::SMR000207397::cid_5722358 Disintegrin and metalloproteinase domain-containing protein 17 9747 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=65996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=65996&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91897603 252644330 ZINC36047042 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235584 CC(=O)c1cccc(NC(=O)C(OC(=O)c2ccccc2NS(=O)(=O)c2cccs2)c2ccccc2)c1 InChI=1S/C27H22N2O6S2/c1-18(30)20-11-7-12-21(17-20)28-26(31)25(19-9-3-2-4-10-19)35-27(32)22-13-5-6-14-23(22)29-37(33,34)24-15-8-16-36-24/h2-17,25,29H,1H3,(H,28,31) NXMSBWZPDMYQRQ-UHFFFAOYSA-N 113879 2-(2-thienylsulfonylamino)benzoic acid [2-(3-acetylanilino)-2-keto-1-phenyl-ethyl] ester::2-(thiophen-2-ylsulfonylamino)benzoic acid [2-(3-acetylanilino)-2-oxo-1-phenylethyl] ester::MLS000374570::SMR000244185::[2-(3-acetylanilino)-2-oxo-1-phenylethyl] 2-(thiophen-2-ylsulfonylamino)benzoate::[2-[(3-ethanoylphenyl)amino]-2-oxidanylidene-1-phenyl-ethyl] 2-(thiophen-2-ylsulfonylamino)benzoate::cid_3540946 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113879 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113879&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3540946 252663410 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235585 COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(=O)Nc3ccc(cc3)C(C)=O)c2c1 InChI=1S/C27H23ClN2O4/c1-16-23(15-26(32)29-21-10-6-18(7-11-21)17(2)31)24-14-22(34-3)12-13-25(24)30(16)27(33)19-4-8-20(28)9-5-19/h4-14H,15H2,1-3H3,(H,29,32) WEFNGJKGIXEMAB-UHFFFAOYSA-N 113880 2-[1-(4-chlorophenyl)carbonyl-5-methoxy-2-methyl-indol-3-yl]-N-(4-ethanoylphenyl)ethanamide::MLS000375172::N-(4-acetylphenyl)-2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-indol-3-yl]acetamide::N-(4-acetylphenyl)-2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetamide::N-(4-acetylphenyl)-2-[1-[(4-chlorophenyl)-oxomethyl]-5-methoxy-2-methyl-3-indolyl]acetamide::SMR000254425::cid_4201507 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113880 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113880&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4201507 252663411 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235586 CCN(CC)c1ccc(NC(=O)COc2ccccc2C)cc1S(=O)(=O)Nc1ccccc1OC InChI=1S/C26H31N3O5S/c1-5-29(6-2)22-16-15-20(27-26(30)18-34-23-13-9-7-11-19(23)3)17-25(22)35(31,32)28-21-12-8-10-14-24(21)33-4/h7-17,28H,5-6,18H2,1-4H3,(H,27,30) PBTUWXCLUPICOD-UHFFFAOYSA-N 80182 MLS000339532::N-[4-(diethylamino)-3-[(2-methoxyphenyl)sulfamoyl]phenyl]-2-(2-methylphenoxy)acetamide::N-[4-(diethylamino)-3-[(2-methoxyphenyl)sulfamoyl]phenyl]-2-(2-methylphenoxy)ethanamide::SMR000244147::cid_4361310 Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=80182 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=80182&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4361310 252656821 ZINC08685553 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235587 COc1ccccc1NC(=O)c1c(N)c(sc1Nc1ccccc1C)C(=O)Nc1cccc(Cl)c1 InChI=1S/C26H23ClN4O3S/c1-15-8-3-4-11-18(15)31-26-21(24(32)30-19-12-5-6-13-20(19)34-2)22(28)23(35-26)25(33)29-17-10-7-9-16(27)14-17/h3-14,31H,28H2,1-2H3,(H,29,33)(H,30,32) RGMBRQQTDUXHPX-UHFFFAOYSA-N 68053 3-amino-2-N-(3-chlorophenyl)-4-N-(2-methoxyphenyl)-5-(2-methylanilino)thiophene-2,4-dicarboxamide::3-amino-N-(3-chlorophenyl)-N'-(2-methoxyphenyl)-5-(o-toluidino)thiophene-2,4-dicarboxamide::3-amino-N2-(3-chlorophenyl)-N4-(2-methoxyphenyl)-5-(2-methylanilino)thiophene-2,4-dicarboxamide::3-azanyl-N2-(3-chlorophenyl)-N4-(2-methoxyphenyl)-5-[(2-methylphenyl)amino]thiophene-2,4-dicarboxamide::MLS000394900::SMR000262185::cid_2439674 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68053&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2439674 252646332 ZINC03324194 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235588 COCCN=c1scc(-c2cc(OC)ccc2OC)n1N=Cc1c[nH]c2ccccc12 InChI=1S/C23H24N4O3S/c1-28-11-10-24-23-27(26-14-16-13-25-20-7-5-4-6-18(16)20)21(15-31-23)19-12-17(29-2)8-9-22(19)30-3/h4-9,12-15,25H,10-11H2,1-3H3 HJTRYLBBSBWKDJ-UHFFFAOYSA-N 54807 4-(2,5-dimethoxyphenyl)-N-[(Z)-3-indolylidenemethyl]-2-(2-methoxyethylimino)-3-thiazolamine::4-(2,5-dimethoxyphenyl)-N-[(Z)-indol-3-ylidenemethyl]-2-(2-methoxyethylimino)-1,3-thiazol-3-amine::MLS000375345::SMR000254598::[4-(2,5-dimethoxyphenyl)-2-(2-methoxyethylimino)-4-thiazolin-3-yl]-[(Z)-indol-3-ylidenemethyl]amine::cid_6508436 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54807&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6508436 252634824 ZINC00532224 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235589 COCCN=c1scc(-c2cc(OC)c(OC)c(OC)c2)n1N=Cc1c(C)[nH]c2ccccc12 InChI=1S/C25H28N4O4S/c1-16-19(18-8-6-7-9-20(18)28-16)14-27-29-21(15-34-25(29)26-10-11-30-2)17-12-22(31-3)24(33-5)23(13-17)32-4/h6-9,12-15,28H,10-11H2,1-5H3/b26-25-,27-14+ OTVPLLNEWZULNQ-HJQQBXHUSA-N 88885 2-(2-methoxyethylimino)-N-[(Z)-(2-methyl-3-indolylidene)methyl]-4-(3,4,5-trimethoxyphenyl)-3-thiazolamine::2-(2-methoxyethylimino)-N-[(Z)-(2-methylindol-3-ylidene)methyl]-4-(3,4,5-trimethoxyphenyl)-1,3-thiazol-3-amine::MLS000375263::SMR000254516::[2-(2-methoxyethylimino)-4-(3,4,5-trimethoxyphenyl)-4-thiazolin-3-yl]-[(Z)-(2-methylindol-3-ylidene)methyl]amine::cid_6039611 Disintegrin and metalloproteinase domain-containing protein 17 69503 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=88885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=88885&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6039611 252660501 ZINC38176798 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235590 O=C(COC(=O)CCCSc1nc2ccccc2[nH]1)Nc1ccc(Oc2ccccc2)cc1 InChI=1S/C25H23N3O4S/c29-23(26-18-12-14-20(15-13-18)32-19-7-2-1-3-8-19)17-31-24(30)11-6-16-33-25-27-21-9-4-5-10-22(21)28-25/h1-5,7-10,12-15H,6,11,16-17H2,(H,26,29)(H,27,28) BVCQNERUSOKMJK-UHFFFAOYSA-N 113881 4-(1H-benzimidazol-2-ylthio)butanoic acid [2-oxo-2-(4-phenoxyanilino)ethyl] ester::4-(1H-benzimidazol-2-ylthio)butyric acid [2-keto-2-(4-phenoxyanilino)ethyl] ester::MLS000416469::SMR000264243::[2-oxidanylidene-2-[(4-phenoxyphenyl)amino]ethyl] 4-(1H-benzimidazol-2-ylsulfanyl)butanoate::[2-oxo-2-(4-phenoxyanilino)ethyl] 4-(1H-benzimidazol-2-ylsulfanyl)butanoate::cid_2401602 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113881 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113881&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2401602 252663412 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235591 COc1ccc(cc1)N=C(C)c1sc2ccccc2c1O InChI=1S/C17H15NO2S/c1-11(18-12-7-9-13(20-2)10-8-12)17-16(19)14-5-3-4-6-15(14)21-17/h3-10,19H,1-2H3 JQNSVUIKOBFNPM-UHFFFAOYSA-N 52782 (2Z)-2-[1-(4-methoxyanilino)ethylidene]-1-benzothiophen-3-one::(2Z)-2-[1-(p-anisidino)ethylidene]benzothiophen-3-one::(2Z)-2-[1-[(4-methoxyphenyl)amino]ethylidene]-1-benzothiophen-3-one::2-[1-(4-Methoxy-phenylamino)-eth-(Z)-ylidene]-benzo[b]thiophen-3-one::MLS000778266::SMR000414940::cid_5421136 Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52782&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5421136 252632919 ZINC03229410 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235592 Cc1ccccc1\N=C1/SC(CC(=O)Nc2ccc3ccccc3c2)C(=O)N1Cc1ccccn1 InChI=1S/C28H24N4O2S/c1-19-8-2-5-12-24(19)31-28-32(18-23-11-6-7-15-29-23)27(34)25(35-28)17-26(33)30-22-14-13-20-9-3-4-10-21(20)16-22/h2-16,25H,17-18H2,1H3,(H,30,33)/b31-28- CCKTYTPEQBNMIC-PNOGMODKSA-N 72299 2-[2-(2-methylphenyl)imino-4-oxidanylidene-3-(pyridin-2-ylmethyl)-1,3-thiazolidin-5-yl]-N-naphthalen-2-yl-ethanamide::2-[2-(2-methylphenyl)imino-4-oxo-3-(2-pyridinylmethyl)-5-thiazolidinyl]-N-(2-naphthalenyl)acetamide::2-[2-(2-methylphenyl)imino-4-oxo-3-(pyridin-2-ylmethyl)-1,3-thiazolidin-5-yl]-N-naphthalen-2-ylacetamide::2-[4-keto-2-(o-tolylimino)-3-(2-pyridylmethyl)thiazolidin-5-yl]-N-(2-naphthyl)acetamide::MLS000392490::SMR000261485::cid_4022978 Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72299 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72299&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4022978 252649562 ZINC18246118 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235593 FC(F)(F)Oc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c2cccs2)cc1 InChI=1S/C23H18F3N3O3S/c24-23(25,26)32-16-9-7-15(8-10-16)28-21(30)19(29-22(31)20-6-3-11-33-20)12-14-13-27-18-5-2-1-4-17(14)18/h1-11,13,19,27H,12H2,(H,28,30)(H,29,31) DIZZJHXXEGTXPO-UHFFFAOYSA-N 113882 MLS000335097::N-[1-(1H-indol-3-ylmethyl)-2-keto-2-[4-(trifluoromethoxy)anilino]ethyl]thiophene-2-carboxamide::N-[3-(1H-indol-3-yl)-1-oxidanylidene-1-[[4-(trifluoromethyloxy)phenyl]amino]propan-2-yl]thiophene-2-carboxamide::N-[3-(1H-indol-3-yl)-1-oxo-1-[4-(trifluoromethoxy)anilino]propan-2-yl]-2-thiophenecarboxamide::N-[3-(1H-indol-3-yl)-1-oxo-1-[4-(trifluoromethoxy)anilino]propan-2-yl]thiophene-2-carboxamide::SMR000249855::cid_3943571 Disintegrin and metalloproteinase domain-containing protein 17 69506 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113882 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113882&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3943571 252663413 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235594 Cc1ccc(N(CC(=O)NCCc2ccc(F)cc2)S(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)c(C)c1 InChI=1S/C24H23ClFN3O5S/c1-16-3-10-22(17(2)13-16)28(15-24(30)27-12-11-18-4-6-19(26)7-5-18)35(33,34)20-8-9-21(25)23(14-20)29(31)32/h3-10,13-14H,11-12,15H2,1-2H3,(H,27,30) BEPPXYSGSJDPQA-UHFFFAOYSA-N 72302 2-(N-(4-chloro-3-nitro-phenyl)sulfonyl-2,4-dimethyl-anilino)-N-[2-(4-fluorophenyl)ethyl]acetamide::2-(N-(4-chloro-3-nitrophenyl)sulfonyl-2,4-dimethylanilino)-N-[2-(4-fluorophenyl)ethyl]acetamide::2-[(4-chloranyl-3-nitro-phenyl)sulfonyl-(2,4-dimethylphenyl)amino]-N-[2-(4-fluorophenyl)ethyl]ethanamide::MLS000339653::SMR000242070::cid_3973468 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=72302 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=72302&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3973468 252649565 ZINC08685589 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235595 Cc1ccc(NC(=O)c2cc3CCCCc3s2)cc1S(=O)(=O)Nc1ccccc1Cl InChI=1S/C22H21ClN2O3S2/c1-14-10-11-16(24-22(26)20-12-15-6-2-5-9-19(15)29-20)13-21(14)30(27,28)25-18-8-4-3-7-17(18)23/h3-4,7-8,10-13,25H,2,5-6,9H2,1H3,(H,24,26) GTOTYNGNWAPMAA-UHFFFAOYSA-N 113883 MLS000394969::N-[3-[(2-chlorophenyl)sulfamoyl]-4-methyl-phenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide::N-[3-[(2-chlorophenyl)sulfamoyl]-4-methyl-phenyl]-4,5,6,7-tetrahydrobenzothiophene-2-carboxamide::N-[3-[(2-chlorophenyl)sulfamoyl]-4-methylphenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide::SMR000248452::cid_4301424 Disintegrin and metalloproteinase domain-containing protein 17 69492 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113883 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113883&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4301424 252663414 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235596 COC(=O)c1ccc(cc1)-n1c(C)cc(CN=Nc2nc(C)cc(=O)[nH]2)c1C InChI=1S/C20H21N5O3/c1-12-9-18(26)23-20(22-12)24-21-11-16-10-13(2)25(14(16)3)17-7-5-15(6-8-17)19(27)28-4/h5-10H,11H2,1-4H3,(H,22,23,26) BPYFJGXJQUXTRN-UHFFFAOYSA-N 52791 4-[2,5-dimethyl-3-[[(6-methyl-4-oxo-1H-pyrimidin-2-yl)hydrazinylidene]methyl]-1-pyrrolyl]benzoic acid methyl ester::4-[3-[[(4-keto-6-methyl-1H-pyrimidin-2-yl)hydrazono]methyl]-2,5-dimethyl-pyrrol-1-yl]benzoic acid methyl ester::MLS000773750::SMR000364461::cid_4396662::methyl 4-[2,5-dimethyl-3-[[(6-methyl-4-oxidanylidene-1H-pyrimidin-2-yl)hydrazinylidene]methyl]pyrrol-1-yl]benzoate::methyl 4-[2,5-dimethyl-3-[[(6-methyl-4-oxo-1H-pyrimidin-2-yl)hydrazinylidene]methyl]pyrrol-1-yl]benzoate Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52791&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91897084 252632928 ZINC08693875 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235597 CN1C(=O)N(C)C(=O)C(=CNCCCCCCCCCCC(O)=O)C1=O InChI=1S/C18H29N3O5/c1-20-16(24)14(17(25)21(2)18(20)26)13-19-12-10-8-6-4-3-5-7-9-11-15(22)23/h13,19H,3-12H2,1-2H3,(H,22,23) OIBAIQYQCNVSFD-UHFFFAOYSA-N 52793 11-[(1,3-Dimethyl-2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidenemethyl)-amino]-undecanoic acid::11-[(1,3-dimethyl-2,4,6-trioxo-1,3-diazinan-5-ylidene)methylamino]undecanoic acid::11-[(2,4,6-triketo-1,3-dimethyl-hexahydropyrimidin-5-ylidene)methylamino]undecanoic acid::11-[[1,3-dimethyl-2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methylamino]undecanoic acid::MLS000777151::SMR000413547::cid_5921568 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52793&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5921568 252632930 ZINC08686662 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235598 Brc1cccc(c1)-c1csc(NC(=O)CSc2nc3ccccc3[nH]2)n1 InChI=1S/C18H13BrN4OS2/c19-12-5-3-4-11(8-12)15-9-25-18(22-15)23-16(24)10-26-17-20-13-6-1-2-7-14(13)21-17/h1-9H,10H2,(H,20,21)(H,22,23,24) UYIMXARMASWBOV-UHFFFAOYSA-N 113884 2-(1H-benzimidazol-2-ylsulfanyl)-N-[4-(3-bromophenyl)-1,3-thiazol-2-yl]acetamide::2-(1H-benzimidazol-2-ylsulfanyl)-N-[4-(3-bromophenyl)-1,3-thiazol-2-yl]ethanamide::2-(1H-benzimidazol-2-ylthio)-N-[4-(3-bromophenyl)-2-thiazolyl]acetamide::2-(1H-benzimidazol-2-ylthio)-N-[4-(3-bromophenyl)thiazol-2-yl]acetamide::MLS000389804::SMR000256078::cid_2389705 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113884 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113884&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2389705 252663415 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235599 CCOC(=O)c1c(C)c(C)sc1NC(=O)CN1C(=O)NC(C)(C1=O)c1ccc(OC(F)F)cc1 InChI=1S/C22H23F2N3O6S/c1-5-32-18(29)16-11(2)12(3)34-17(16)25-15(28)10-27-19(30)22(4,26-21(27)31)13-6-8-14(9-7-13)33-20(23)24/h6-9,20H,5,10H2,1-4H3,(H,25,28)(H,26,31) LETJEJFWSPLWMI-UHFFFAOYSA-N 113885 2-[[2-[4-[4-(difluoromethoxy)phenyl]-2,5-diketo-4-methyl-imidazolidin-1-yl]acetyl]amino]-4,5-dimethyl-thiophene-3-carboxylic acid ethyl ester::2-[[2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxo-1-imidazolidinyl]-1-oxoethyl]amino]-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester::MLS000388704::SMR000254877::cid_4008602::ethyl 2-[2-[4-[4-[bis(fluoranyl)methoxy]phenyl]-4-methyl-2,5-bis(oxidanylidene)imidazolidin-1-yl]ethanoylamino]-4,5-dimethyl-thiophene-3-carboxylate::ethyl 2-[[2-[4-[4-(difluoromethoxy)phenyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]acetyl]amino]-4,5-dimethylthiophene-3-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69486 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113885 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113885&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4008602 252663416 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235600 Brc1ccc(NC(=O)CC2S\C(=N/c3ccccc3)N(Cc3ccccn3)C2=O)cc1 InChI=1S/C23H19BrN4O2S/c24-16-9-11-18(12-10-16)26-21(29)14-20-22(30)28(15-19-8-4-5-13-25-19)23(31-20)27-17-6-2-1-3-7-17/h1-13,20H,14-15H2,(H,26,29)/b27-23- ATLCZWDEYFPENC-VYIQYICTSA-N 113886 MLS000392407::N-(4-bromophenyl)-2-[4-keto-2-phenylimino-3-(2-pyridylmethyl)thiazolidin-5-yl]acetamide::N-(4-bromophenyl)-2-[4-oxidanylidene-2-phenylimino-3-(pyridin-2-ylmethyl)-1,3-thiazolidin-5-yl]ethanamide::N-(4-bromophenyl)-2-[4-oxo-2-phenylimino-3-(2-pyridinylmethyl)-5-thiazolidinyl]acetamide::N-(4-bromophenyl)-2-[4-oxo-2-phenylimino-3-(pyridin-2-ylmethyl)-1,3-thiazolidin-5-yl]acetamide::SMR000261358::cid_4441779 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113886 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113886&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4441779 252663417 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235601 FC(F)(F)c1cccc(NC(=S)NCC2COc3ccccc3O2)c1 InChI=1S/C17H15F3N2O2S/c18-17(19,20)11-4-3-5-12(8-11)22-16(25)21-9-13-10-23-14-6-1-2-7-15(14)24-13/h1-8,13H,9-10H2,(H2,21,22,25) WMWFQZNCWFRHPR-UHFFFAOYSA-N 113887 1-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-[3-(trifluoromethyl)phenyl]thiourea::MLS000334790::SMR000249548::cid_4836220 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113887 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113887&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4836220 252663418 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235602 Cc1ccc(cc1)-n1c(SCC(=O)Nc2cccc(c2)S(N)(=O)=O)nc2ccccc12 InChI=1S/C22H20N4O3S2/c1-15-9-11-17(12-10-15)26-20-8-3-2-7-19(20)25-22(26)30-14-21(27)24-16-5-4-6-18(13-16)31(23,28)29/h2-13H,14H2,1H3,(H,24,27)(H2,23,28,29) MCQGUUXUHCSZSE-UHFFFAOYSA-N 113888 2-[1-(4-methylphenyl)benzimidazol-2-yl]sulfanyl-N-(3-sulfamoylphenyl)acetamide::2-[1-(4-methylphenyl)benzimidazol-2-yl]sulfanyl-N-(3-sulfamoylphenyl)ethanamide::2-[[1-(4-methylphenyl)-2-benzimidazolyl]thio]-N-(3-sulfamoylphenyl)acetamide::2-[[1-(p-tolyl)benzimidazol-2-yl]thio]-N-(3-sulfamoylphenyl)acetamide::MLS000416794::SMR000241858::cid_4879538 Disintegrin and metalloproteinase domain-containing protein 17 69496 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113888&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4879538 252663419 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235603 COc1ccc(NC(=O)c2ccc(cc2)-c2ccccc2)cc1NS(=O)(=O)c1ccc(F)cc1 InChI=1S/C26H21FN2O4S/c1-33-25-16-13-22(17-24(25)29-34(31,32)23-14-11-21(27)12-15-23)28-26(30)20-9-7-19(8-10-20)18-5-3-2-4-6-18/h2-17,29H,1H3,(H,28,30) DVLMVJILWFSRPS-UHFFFAOYSA-N 113889 MLS000417014::N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxy-phenyl]-4-phenyl-benzamide::N-[3-[(4-fluorophenyl)sulfonylamino]-4-methoxyphenyl]-4-phenylbenzamide::SMR000241960::cid_5020799 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113889&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5020799 252663420 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235604 Oc1c(C=NCCN2CCCCC2)c(=O)[nH]c(=O)n1-c1ccc(Br)cc1 InChI=1S/C18H21BrN4O3/c19-13-4-6-14(7-5-13)23-17(25)15(16(24)21-18(23)26)12-20-8-11-22-9-2-1-3-10-22/h4-7,12,25H,1-3,8-11H2,(H,21,24,26) OEGTVGJUWAGVOD-UHFFFAOYSA-N 52809 (5E)-1-(4-bromophenyl)-5-[(2-piperidin-1-ylethylamino)methylidene]-1,3-diazinane-2,4,6-trione::(5E)-1-(4-bromophenyl)-5-[(2-piperidinoethylamino)methylene]barbituric acid::(5E)-1-(4-bromophenyl)-5-[[2-(1-piperidinyl)ethylamino]methylidene]-1,3-diazinane-2,4,6-trione::1-(4-Bromo-phenyl)-5-[1-(2-piperidin-1-yl-ethylamino)-meth-(E)-ylidene]-pyrimidine-2,4,6-trione::MLS000767897::SMR000431219::cid_5545304 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52809&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5545304 252632946 ZINC03584867 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235605 COc1cc(\C=N\OCC(=O)Nc2ccc(OC(F)F)cc2)ccc1OCc1ccccc1 InChI=1S/C24H22F2N2O5/c1-30-22-13-18(7-12-21(22)31-15-17-5-3-2-4-6-17)14-27-32-16-23(29)28-19-8-10-20(11-9-19)33-24(25)26/h2-14,24H,15-16H2,1H3,(H,28,29)/b27-14+ VMGUYXNMCYHGEQ-MZJWZYIUSA-N 113890 2-[(E)-(4-benzoxy-3-methoxy-benzylidene)amino]oxy-N-[4-(difluoromethoxy)phenyl]acetamide::MLS000390347::N-[4-(difluoromethoxy)phenyl]-2-[(E)-(3-methoxy-4-phenylmethoxyphenyl)methylideneamino]oxyacetamide::N-[4-[bis(fluoranyl)methoxy]phenyl]-2-[(E)-(3-methoxy-4-phenylmethoxy-phenyl)methylideneamino]oxy-ethanamide::SMR000255314::cid_6893064 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113890&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6893064 252663421 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235606 Cc1cc(C)c(cc1C)-c1cc(NC(=O)COC(=O)c2ccc(cc2)C#N)n(n1)-c1ccccc1 InChI=1S/C28H24N4O3/c1-18-13-20(3)24(14-19(18)2)25-15-26(32(31-25)23-7-5-4-6-8-23)30-27(33)17-35-28(34)22-11-9-21(16-29)10-12-22/h4-15H,17H2,1-3H3,(H,30,33) GIFIZUQPCYWXLZ-UHFFFAOYSA-N 64641 4-cyanobenzoic acid [2-keto-2-[[2-phenyl-5-(2,4,5-trimethylphenyl)pyrazol-3-yl]amino]ethyl] ester::4-cyanobenzoic acid [2-oxo-2-[[2-phenyl-5-(2,4,5-trimethylphenyl)-3-pyrazolyl]amino]ethyl] ester::MLS000335314::SMR000250072::[2-oxidanylidene-2-[[2-phenyl-5-(2,4,5-trimethylphenyl)pyrazol-3-yl]amino]ethyl] 4-cyanobenzoate::[2-oxo-2-[[2-phenyl-5-(2,4,5-trimethylphenyl)pyrazol-3-yl]amino]ethyl] 4-cyanobenzoate::cid_2531633 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64641&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2531633 252643674 ZINC03412661 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235607 COc1ccccc1N(CC=C)S(=O)(=O)c1cccc(c1)C(=O)OCC(=O)c1c[nH]c2ccccc12 InChI=1S/C27H24N2O6S/c1-3-15-29(24-13-6-7-14-26(24)34-2)36(32,33)20-10-8-9-19(16-20)27(31)35-18-25(30)22-17-28-23-12-5-4-11-21(22)23/h3-14,16-17,28H,1,15,18H2,2H3 FALPZHDUKBLXOH-UHFFFAOYSA-N 113891 3-[(2-methoxyphenyl)-prop-2-enylsulfamoyl]benzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester::3-[allyl-(2-methoxyphenyl)sulfamoyl]benzoic acid [2-(1H-indol-3-yl)-2-keto-ethyl] ester::MLS000417875::SMR000243374::[2-(1H-indol-3-yl)-2-oxidanylidene-ethyl] 3-[(2-methoxyphenyl)-prop-2-enyl-sulfamoyl]benzoate::[2-(1H-indol-3-yl)-2-oxoethyl] 3-[(2-methoxyphenyl)-prop-2-enylsulfamoyl]benzoate::cid_2116235 Disintegrin and metalloproteinase domain-containing protein 17 69488 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113891 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113891&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2116235 252663422 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235608 O=S(=O)(N1CCOCC1)c1ccc(NC(=S)NCCC(c2ccccc2)c2ccccc2)cc1 InChI=1S/C26H29N3O3S2/c30-34(31,29-17-19-32-20-18-29)24-13-11-23(12-14-24)28-26(33)27-16-15-25(21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14,25H,15-20H2,(H2,27,28,33) ZXDSCOUTHNCCEH-UHFFFAOYSA-N 113892 1-(3,3-diphenylpropyl)-3-(4-morpholin-4-ylsulfonylphenyl)thiourea::1-(3,3-diphenylpropyl)-3-(4-morpholinosulfonylphenyl)thiourea::1-(3,3-diphenylpropyl)-3-[4-(4-morpholinylsulfonyl)phenyl]thiourea::MLS000374646::SMR000244261::cid_3601294 Disintegrin and metalloproteinase domain-containing protein 17 69489 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113892 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113892&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3601294 252663423 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235609 Clc1ccc(cc1S(=O)(=O)N1CCCCCC1)C(=O)OCC(=O)Nc1ccccc1 InChI=1S/C21H23ClN2O5S/c22-18-11-10-16(14-19(18)30(27,28)24-12-6-1-2-7-13-24)21(26)29-15-20(25)23-17-8-4-3-5-9-17/h3-5,8-11,14H,1-2,6-7,12-13,15H2,(H,23,25) HOXYAQNEUYGXDR-UHFFFAOYSA-N 113893 (2-anilino-2-oxoethyl) 3-(azepan-1-ylsulfonyl)-4-chlorobenzoate::(2-oxidanylidene-2-phenylazanyl-ethyl) 3-(azepan-1-ylsulfonyl)-4-chloranyl-benzoate::3-(1-azepanylsulfonyl)-4-chlorobenzoic acid (2-anilino-2-oxoethyl) ester::3-(azepan-1-ylsulfonyl)-4-chloro-benzoic acid (2-anilino-2-keto-ethyl) ester::MLS000393469::SMR000241358::cid_2122384 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113893 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113893&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2122384 252663424 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235610 Cc1cccc(Oc2nc(nc3ccccc23)-c2ccccn2)c1 InChI=1S/C20H15N3O/c1-14-7-6-8-15(13-14)24-20-16-9-2-3-10-17(16)22-19(23-20)18-11-4-5-12-21-18/h2-13H,1H3 NNBPTCAWASUKMR-UHFFFAOYSA-N 52822 2-Pyridin-2-yl-4-m-tolyloxy-quinazoline::4-(3-methylphenoxy)-2-(2-pyridinyl)quinazoline::4-(3-methylphenoxy)-2-(2-pyridyl)quinazoline::4-(3-methylphenoxy)-2-pyridin-2-yl-quinazoline::4-(3-methylphenoxy)-2-pyridin-2-ylquinazoline::MLS000769548::SMR000434270::cid_930112 Disintegrin and metalloproteinase domain-containing protein 17 69512 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52822&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 930112 252632958 ZINC08686480 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235611 COc1ccccc1NS(=O)(=O)c1cccc(NC(=O)Nc2cccc(Cl)c2)c1 InChI=1S/C20H18ClN3O4S/c1-28-19-11-3-2-10-18(19)24-29(26,27)17-9-5-8-16(13-17)23-20(25)22-15-7-4-6-14(21)12-15/h2-13,24H,1H3,(H2,22,23,25) IYTDIHBYTAIGOJ-UHFFFAOYSA-N 95734 1-(3-chlorophenyl)-3-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]urea::MLS000417430::SMR000242621::cid_4178848 Disintegrin and metalloproteinase domain-containing protein 17 69496 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95734&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4178848 164036978 ZINC08686943 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235612 CN(C)c1ccc(cc1)C(CNS(=O)(=O)c1ccc(F)cc1)c1c[nH]c2ccccc12 InChI=1S/C24H24FN3O2S/c1-28(2)19-11-7-17(8-12-19)22(23-15-26-24-6-4-3-5-21(23)24)16-27-31(29,30)20-13-9-18(25)10-14-20/h3-15,22,26-27H,16H2,1-2H3 IJEAMDHJBDGPQH-UHFFFAOYSA-N 113894 MLS000392986::N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]-4-fluoranyl-benzenesulfonamide::N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]-4-fluoro-benzenesulfonamide::N-[2-[4-(dimethylamino)phenyl]-2-(1H-indol-3-yl)ethyl]-4-fluorobenzenesulfonamide::SMR000248125::cid_4283512 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113894 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113894&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4283512 252663425 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235613 COC(=O)CCCC1=CC2=CC(=O)C(C)(OC(=O)C3CCCC3)C(=O)C2=CO1 InChI=1S/C21H24O7/c1-21(28-20(25)13-6-3-4-7-13)17(22)11-14-10-15(8-5-9-18(23)26-2)27-12-16(14)19(21)24/h10-13H,3-9H2,1-2H3 ZRVYBMPHJCOKOU-UHFFFAOYSA-N 52890 CMLD003357::MLS000438839::SMR000452591::[3-(4-methoxy-4-oxidanylidene-butyl)-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] cyclopentanecarboxylate::[3-(4-methoxy-4-oxobutyl)-7-methyl-6,8-dioxoisochromen-7-yl] cyclopentanecarboxylate::cid_16745664::cyclopentanecarboxylic acid [3-(4-methoxy-4-oxobutyl)-7-methyl-6,8-dioxo-2-benzopyran-7-yl] ester::cyclopentanecarboxylic acid [6,8-diketo-3-(4-keto-4-methoxy-butyl)-7-methyl-isochromen-7-yl] ester Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52890&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16745664 252633024 ZINC04178224 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235614 Cc1ccc(cc1)C(=O)Nc1nnc(NC(=S)Nc2ccccc2)s1 InChI=1S/C17H15N5OS2/c1-11-7-9-12(10-8-11)14(23)19-16-21-22-17(25-16)20-15(24)18-13-5-3-2-4-6-13/h2-10H,1H3,(H,19,21,23)(H2,18,20,22,24) GGGYKZMLOKUQCE-UHFFFAOYSA-N 79563 4-methyl-N-[5-(phenylcarbamothioylamino)-1,3,4-thiadiazol-2-yl]benzamide::4-methyl-N-[5-(phenylthiocarbamoylamino)-1,3,4-thiadiazol-2-yl]benzamide::MLS000390029::N-[5-[[anilino(sulfanylidene)methyl]amino]-1,3,4-thiadiazol-2-yl]-4-methylbenzamide::SMR000259293::cid_1547875 Disintegrin and metalloproteinase domain-containing protein 17 69498 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=79563 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=79563&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1547875 252656211 ZINC13865476 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235615 CCc1ccc(cc1)-c1cn(C2CCCCC2)c(=S)[nH]1 InChI=1S/C17H22N2S/c1-2-13-8-10-14(11-9-13)16-12-19(17(20)18-16)15-6-4-3-5-7-15/h8-12,15H,2-7H2,1H3,(H,18,20) KRFFJZRJIICYEP-UHFFFAOYSA-N 113895 1-cyclohexyl-4-(4-ethylphenyl)-1,3-dihydro-2H-imidazole-2-thione::1-cyclohexyl-4-(4-ethylphenyl)-4-imidazoline-2-thione::3-cyclohexyl-5-(4-ethylphenyl)-1H-imidazole-2-thione::MLS000660940::SMR000310578::cid_4105277 Disintegrin and metalloproteinase domain-containing protein 17 69490 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113895&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4105277 252663426 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235616 S=C(NC1CCCCCC1)Nc1ccc(Nc2ccccc2)cc1 InChI=1S/C20H25N3S/c24-20(22-17-10-4-1-2-5-11-17)23-19-14-12-18(13-15-19)21-16-8-6-3-7-9-16/h3,6-9,12-15,17,21H,1-2,4-5,10-11H2,(H2,22,23,24) BSIRAFKJUYYSLV-UHFFFAOYSA-N 113896 1-(4-anilinophenyl)-3-cycloheptyl-thiourea::1-(4-anilinophenyl)-3-cycloheptylthiourea::1-cycloheptyl-3-(4-phenylazanylphenyl)thiourea::MLS000663680::N-(4-anilinophenyl)-N'-cycloheptylthiourea::SMR000292974::cid_2195983 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113896&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2195983 252663427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235617 CCOc1ccc(cc1)C(Nc1cccnc1)c1cc(Cl)c2cccnc2c1O InChI=1S/C23H20ClN3O2/c1-2-29-17-9-7-15(8-10-17)21(27-16-5-3-11-25-14-16)19-13-20(24)18-6-4-12-26-22(18)23(19)28/h3-14,21,27-28H,2H2,1H3 RDJCCPWITAIICC-UHFFFAOYSA-N 50308030 5-chloro-7-((4-ethoxyphenyl)(pyridin-3-ylamino)methyl)quinolin-8-ol::CHEMBL599255::cid_2977478 Disintegrin and metalloproteinase domain-containing protein 17 9106 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308030&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2977478 104162391 CHEMBL599255 ZINC01066515 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235618 CCC1COC(=[NH+]1)C(=C(/Cl)[C-](Cl)Cl)\[N+]([O-])=O InChI=1S/C8H8Cl3N2O3/c1-2-4-3-16-8(12-4)6(13(14)15)5(9)7(10)11/h4H,2-3H2,1H3/q-1/p+1/b6-5+ SKUNSCJOQKMSBC-AATRIKPKSA-O 113897 (2E)-4-ethyl-2-(2,3,3-trichloro-1-nitro-prop-2-enylidene)oxazolidine::(2E)-4-ethyl-2-(2,3,3-trichloro-1-nitroprop-2-enylidene)-1,3-oxazolidine::(2E)-4-ethyl-2-(2,3,3-trichloro-1-nitroprop-2-enylidene)oxazolidine::(2E)-4-ethyl-2-[2,3,3-tris(chloranyl)-1-nitro-prop-2-enylidene]-1,3-oxazolidine::MLS000724314::SMR000305908::cid_6019211 Disintegrin and metalloproteinase domain-containing protein 17 27869 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113897 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113897&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6019211 252663428 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235619 Oc1cc2OCOc2cc1C(N1CCCC1)c1ccc(Cl)c(Cl)c1 InChI=1S/C18H17Cl2NO3/c19-13-4-3-11(7-14(13)20)18(21-5-1-2-6-21)12-8-16-17(9-15(12)22)24-10-23-16/h3-4,7-9,18,22H,1-2,5-6,10H2 PALXEUVWNGHGKV-UHFFFAOYSA-N 48862 6-[(3,4-dichlorophenyl)(1-pyrrolidinyl)methyl]-1,3-benzodioxol-5-ol::6-[(3,4-dichlorophenyl)-(1-pyrrolidinyl)methyl]-1,3-benzodioxol-5-ol::6-[(3,4-dichlorophenyl)-pyrrolidin-1-yl-methyl]-1,3-benzodioxol-5-ol::6-[(3,4-dichlorophenyl)-pyrrolidin-1-ylmethyl]-1,3-benzodioxol-5-ol::6-[(3,4-dichlorophenyl)-pyrrolidino-methyl]sesamol::MLS000736360::SMR000338310::cid_3309922 Disintegrin and metalloproteinase domain-containing protein 17 19953 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=48862 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=48862&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3309922 252629149 ZINC05890823 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235620 CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)NC(c1ccccc1)c1ccccc1)C(=O)OCc1ccccc1 InChI=1S/C31H32N4O4/c1-21(2)18-25(31(38)39-19-22-12-6-3-7-13-22)34-29(36)27-28(33-20-32-27)30(37)35-26(23-14-8-4-9-15-23)24-16-10-5-11-17-24/h3-17,20-21,25-26H,18-19H2,1-2H3,(H,32,33)(H,34,36)(H,35,37)/t25-/m0/s1 GOEUUEGNHMHLNU-VWLOTQADSA-N 113898 (2S)-2-[[5-(benzhydrylcarbamoyl)-1H-imidazole-4-carbonyl]amino]-4-methyl-valeric acid benzyl ester::(2S)-2-[[[5-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]-4-methylpentanoic acid (phenylmethyl) ester::(phenylmethyl) (2S)-2-[[5-[(diphenylmethyl)carbamoyl]-1H-imidazol-4-yl]carbonylamino]-4-methyl-pentanoate::ILP-II-3::MLS000834717::SMR000394125::benzyl (2S)-2-[[5-(benzhydrylcarbamoyl)-1H-imidazole-4-carbonyl]amino]-4-methylpentanoate::cid_16196394 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113898 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113898&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16196394 252663429 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235621 CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)c1nc[nH]c1C(=O)NC(c1ccccc1)c1ccccc1)C(=O)OC(C)(C)C InChI=1S/C33H43N5O6/c1-32(2,3)43-30(41)24(19-13-14-20-34-31(42)44-33(4,5)6)37-28(39)26-27(36-21-35-26)29(40)38-25(22-15-9-7-10-16-22)23-17-11-8-12-18-23/h7-12,15-18,21,24-25H,13-14,19-20H2,1-6H3,(H,34,42)(H,35,36)(H,37,39)(H,38,40)/t24-/m0/s1 UFEAGCIMDXQMSV-DEOSSOPVSA-N 95947 (2S)-2-[[5-(benzhydrylcarbamoyl)-1H-imidazole-4-carbonyl]amino]-6-(tert-butoxycarbonylamino)hexanoic acid tert-butyl ester::(2S)-2-[[[5-[[(diphenylmethyl)amino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl ester::ILP-II-73::MLS000834715::SMR000394123::cid_16196395::tert-butyl (2S)-2-[[5-(benzhydrylcarbamoyl)-1H-imidazole-4-carbonyl]amino]-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate::tert-butyl (2S)-2-[[5-[(diphenylmethyl)carbamoyl]-1H-imidazol-4-yl]carbonylamino]-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=95947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=95947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16196395 164037191 ZINC17544919 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235622 Oc1cccc(\C=N\N(Cc2ccccc2)c2ccccc2)c1 InChI=1S/C20H18N2O/c23-20-13-7-10-18(14-20)15-21-22(19-11-5-2-6-12-19)16-17-8-3-1-4-9-17/h1-15,23H,16H2/b21-15+ GAKKRBBXFRSTSG-RCCKNPSSSA-N 113899 3-[(E)-[benzyl(phenyl)hydrazinylidene]methyl]phenol::3-[(E)-[benzyl(phenyl)hydrazono]methyl]phenol::3-[(E)-[phenyl-(phenylmethyl)hydrazinylidene]methyl]phenol::MLS000775175::SMR000364924::cid_9630253 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113899&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9630253 252663430 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235623 OC(CNCC(c1c[nH]c2ccccc12)c1ccc(Cl)cc1Cl)c1ccccc1 InChI=1S/C24H22Cl2N2O/c25-17-10-11-18(22(26)12-17)20(21-14-28-23-9-5-4-8-19(21)23)13-27-15-24(29)16-6-2-1-3-7-16/h1-12,14,20,24,27-29H,13,15H2 DHVLQBMFWWTSRF-UHFFFAOYSA-N 68163 2-[[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]amino]-1-phenyl-ethanol::2-[[2-(2,4-dichlorophenyl)-2-(1H-indol-3-yl)ethyl]amino]-1-phenylethanol::MLS001033995::SMR000385827::cid_3947745 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=68163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=68163&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3947745 252646440 ZINC02651794 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235624 OCc1ccc(CO[C@H]2C[C@H](C=C(O2)C(=O)NCc2ccccc2)c2ccc(Br)cc2)cc1 InChI=1S/C27H26BrNO4/c28-24-12-10-22(11-13-24)23-14-25(27(31)29-16-19-4-2-1-3-5-19)33-26(15-23)32-18-21-8-6-20(17-30)7-9-21/h1-14,23,26,30H,15-18H2,(H,29,31)/t23-,26+/m0/s1 WIQXSJOTUJIZEA-JYFHCDHNSA-N 113900 (2R,4R)-4-(4-bromophenyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-N-(phenylmethyl)-3,4-dihydro-2H-pyran-6-carboxamide::(2R,4R)-N-benzyl-4-(4-bromophenyl)-2-(4-methylolbenzyl)oxy-3,4-dihydro-2H-pyran-6-carboxamide::(2R,4R)-N-benzyl-4-(4-bromophenyl)-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-carboxamide::MLS000766595::SMR000442023::cid_16197009 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113900&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16197009 252663431 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235625 FC(F)(F)c1cc(CCN2[C@@H](Cc3ccccc3)CNC2=S)cc(c1)C(F)(F)F InChI=1S/C20H18F6N2S/c21-19(22,23)15-8-14(9-16(11-15)20(24,25)26)6-7-28-17(12-27-18(28)29)10-13-4-2-1-3-5-13/h1-5,8-9,11,17H,6-7,10,12H2,(H,27,29)/t17-/m0/s1 ODKVSFKEMBQORC-KRWDZBQOSA-N 113901 (5S)-1-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-5-(phenylmethyl)-2-imidazolidinethione::(5S)-1-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-5-(phenylmethyl)imidazolidine-2-thione::(5S)-5-benzyl-1-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]imidazolidine-2-thione::MLS000862801::SMR000444668::cid_16197202 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113901&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16197202 252663432 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235626 COc1ccc(N2C(=O)NC(=O)C(=Cc3c[nH]c4ccc(Br)cc34)C2=O)c(OC)c1 InChI=1S/C21H16BrN3O5/c1-29-13-4-6-17(18(9-13)30-2)25-20(27)15(19(26)24-21(25)28)7-11-10-23-16-5-3-12(22)8-14(11)16/h3-10,23H,1-2H3,(H,24,26,28) RFMVSHFCMYFNLC-UHFFFAOYSA-N 53156 (5E)-5-[(5-bromanyl-1H-indol-3-yl)methylidene]-1-(2,4-dimethoxyphenyl)-1,3-diazinane-2,4,6-trione::(5E)-5-[(5-bromo-1H-indol-3-yl)methylene]-1-(2,4-dimethoxyphenyl)barbituric acid::(5E)-5-[(5-bromo-1H-indol-3-yl)methylene]-1-(2,4-dimethoxyphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione::(5E)-5-[(5-bromo-1H-indol-3-yl)methylidene]-1-(2,4-dimethoxyphenyl)-1,3-diazinane-2,4,6-trione::MLS001196551::SMR000556202::cid_16467505 Disintegrin and metalloproteinase domain-containing protein 17 12034 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53156&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16467505 252633288 ZINC18090893 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235627 OC(=O)CCc1ccc(-c2ccccc2)n1-c1cccc(c1)C(O)=O InChI=1S/C20H17NO4/c22-19(23)12-10-16-9-11-18(14-5-2-1-3-6-14)21(16)17-8-4-7-15(13-17)20(24)25/h1-9,11,13H,10,12H2,(H,22,23)(H,24,25) VVNIDALQAIUGOU-UHFFFAOYSA-N 53160 3-[2-(2-carboxyethyl)-5-phenyl-1-pyrrolyl]benzoic acid::3-[2-(2-carboxyethyl)-5-phenyl-1H-pyrrol-1-yl]benzoic acid::3-[2-(2-carboxyethyl)-5-phenyl-pyrrol-1-yl]benzoic acid::3-[2-(2-carboxyethyl)-5-phenylpyrrol-1-yl]benzoic acid::3-[2-(3-hydroxy-3-oxopropyl)-5-phenyl-pyrrol-1-yl]benzoic acid::MLS001195956::SMR000558717::cid_954366 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53160&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 954366 252633292 ZINC18143398 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235628 COc1ccc(cc1OC)-c1c[nH]nc1-c1ccc(OCc2ccccc2)cc1O InChI=1S/C24H22N2O4/c1-28-22-11-8-17(12-23(22)29-2)20-14-25-26-24(20)19-10-9-18(13-21(19)27)30-15-16-6-4-3-5-7-16/h3-14,27H,15H2,1-2H3,(H,25,26) PCIDUQSBVJULLO-UHFFFAOYSA-N 113902 (6E)-3-benzoxy-6-[4-(3,4-dimethoxyphenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[4-(3,4-dimethoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-phenylmethoxy-1-cyclohexa-2,4-dienone::(6E)-6-[4-(3,4-dimethoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-phenylmethoxy-cyclohexa-2,4-dien-1-one::(6E)-6-[4-(3,4-dimethoxyphenyl)-1,2-dihydropyrazol-3-ylidene]-3-phenylmethoxycyclohexa-2,4-dien-1-one::5-Benzyloxy-2-[4-(3,4-dimethoxy-phenyl)-1H-pyrazol-3-yl]-phenol::MLS000778915::SMR000415583::cid_16681776 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113902&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16681776 252663433 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235629 NC(=O)[C@@H]1CC2(CN1C(=O)c1ccc(Cl)cc1)CC(=NO2)c1cccc(NC(=O)CC(c2ccccc2)c2ccccc2)c1 InChI=1S/C35H31ClN4O4/c36-27-16-14-25(15-17-27)34(43)40-22-35(21-31(40)33(37)42)20-30(39-44-35)26-12-7-13-28(18-26)38-32(41)19-29(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-18,29,31H,19-22H2,(H2,37,42)(H,38,41)/t31-,35?/m0/s1 CQLBORDEKDMTEW-MWGAKABSSA-N 113903 (8S)-7-(4-chlorobenzoyl)-3-[3-(3,3-diphenylpropanoylamino)phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8S)-7-(4-chlorophenyl)carbonyl-3-[3-(3,3-diphenylpropanoylamino)phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8S)-7-[(4-chlorophenyl)-oxomethyl]-3-[3-[(1-oxo-3,3-diphenylpropyl)amino]phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::MLS000562060::SMR000390693::cid_16681904 Disintegrin and metalloproteinase domain-containing protein 17 69512 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113903 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113903&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16681904 252663434 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235630 NC(=O)[C@H]1CC2(CN1C(=O)CC(c1ccccc1)c1ccccc1)CC(=NO2)c1cccc(NC(=O)CC(c2ccccc2)c2ccccc2)c1 InChI=1S/C43H40N4O4/c44-42(50)39-28-43(29-47(39)41(49)26-37(32-18-9-3-10-19-32)33-20-11-4-12-21-33)27-38(46-51-43)34-22-13-23-35(24-34)45-40(48)25-36(30-14-5-1-6-15-30)31-16-7-2-8-17-31/h1-24,36-37,39H,25-29H2,(H2,44,50)(H,45,48)/t39-,43?/m1/s1 HSARLDICECHILT-KQKAFOQPSA-N 113904 (8R)-7-(1-oxo-3,3-diphenylpropyl)-3-[3-[(1-oxo-3,3-diphenylpropyl)amino]phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8R)-7-(3,3-diphenylpropanoyl)-3-[3-(3,3-diphenylpropanoylamino)phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::MLS000562100::SMR000390682::cid_16681919 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113904&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16681919 252663435 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235631 NC(=O)[C@H]1CC2(CN1C(=O)C(c1ccccc1)c1ccccc1)CC(=NO2)c1cccc(NC(=O)COc2ccc(Cl)cc2)c1 InChI=1S/C35H31ClN4O5/c36-26-14-16-28(17-15-26)44-21-31(41)38-27-13-7-12-25(18-27)29-19-35(45-39-29)20-30(33(37)42)40(22-35)34(43)32(23-8-3-1-4-9-23)24-10-5-2-6-11-24/h1-18,30,32H,19-22H2,(H2,37,42)(H,38,41)/t30-,35?/m1/s1 GHAMIKUGMNHNGL-OSRRZMJMSA-N 113905 (8R)-3-[3-[2-(4-chloranylphenoxy)ethanoylamino]phenyl]-7-(2,2-diphenylethanoyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8R)-3-[3-[[2-(4-chlorophenoxy)-1-oxoethyl]amino]phenyl]-7-(1-oxo-2,2-diphenylethyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8R)-3-[3-[[2-(4-chlorophenoxy)acetyl]amino]phenyl]-7-(2,2-diphenylacetyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::MLS000562046::SMR000390710::cid_16681959 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113905&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16681959 252663436 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235632 NC(=O)[C@@H]1CC2(CN1C(=O)COc1ccc(Cl)cc1)CC(=NO2)c1cccc(NC(=O)CC(c2ccccc2)c2ccccc2)c1 InChI=1S/C36H33ClN4O5/c37-27-14-16-29(17-15-27)45-22-34(43)41-23-36(21-32(41)35(38)44)20-31(40-46-36)26-12-7-13-28(18-26)39-33(42)19-30(24-8-3-1-4-9-24)25-10-5-2-6-11-25/h1-18,30,32H,19-23H2,(H2,38,44)(H,39,42)/t32-,36?/m0/s1 RZUNWHFACXXCOI-URKOMERPSA-N 113906 (8S)-7-[2-(4-chloranylphenoxy)ethanoyl]-3-[3-(3,3-diphenylpropanoylamino)phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8S)-7-[2-(4-chlorophenoxy)-1-oxoethyl]-3-[3-[(1-oxo-3,3-diphenylpropyl)amino]phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::(8S)-7-[2-(4-chlorophenoxy)acetyl]-3-[3-(3,3-diphenylpropanoylamino)phenyl]-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide::MLS000562054::SMR000390683::cid_16682058 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113906&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16682058 252663437 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235633 COc1ccc2nc(SCC(=O)Nc3ccc(cc3)S(=O)(=O)N3CCCC3)c(cc2c1)C#N InChI=1S/C23H22N4O4S2/c1-31-19-6-9-21-16(13-19)12-17(14-24)23(26-21)32-15-22(28)25-18-4-7-20(8-5-18)33(29,30)27-10-2-3-11-27/h4-9,12-13H,2-3,10-11,15H2,1H3,(H,25,28) CBVFDFXPWIUTDX-UHFFFAOYSA-N 113907 2-(3-Cyano-6-methoxy-quinolin-2-ylsulfanyl)-N-[4-(pyrrolidine-1-sulfonyl)-phenyl]-acetamide::2-(3-cyano-6-methoxy-quinolin-2-yl)sulfanyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)ethanamide::2-(3-cyano-6-methoxyquinolin-2-yl)sulfanyl-N-(4-pyrrolidin-1-ylsulfonylphenyl)acetamide::2-[(3-cyano-6-methoxy-2-quinolinyl)thio]-N-[4-(1-pyrrolidinylsulfonyl)phenyl]acetamide::2-[(3-cyano-6-methoxy-2-quinolyl)thio]-N-(4-pyrrolidinosulfonylphenyl)acetamide::MLS000889332::SMR000007878::cid_644935 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113907&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 644935 252663438 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235634 O=C(CCn1cnc2ccccc2c1=O)Nc1oc(c(c1C#N)-c1ccccc1)-c1ccccc1 InChI=1S/C28H20N4O3/c29-17-22-25(19-9-3-1-4-10-19)26(20-11-5-2-6-12-20)35-27(22)31-24(33)15-16-32-18-30-23-14-8-7-13-21(23)28(32)34/h1-14,18H,15-16H2,(H,31,33) TUAZFWZUARZJBU-UHFFFAOYSA-N 113908 MLS000863132::N-(3-cyano-4,5-diphenyl-2-furanyl)-3-(4-oxo-3-quinazolinyl)propanamide::N-(3-cyano-4,5-diphenyl-2-furyl)-3-(4-ketoquinazolin-3-yl)propionamide::N-(3-cyano-4,5-diphenyl-2-furyl)-3-(4-oxo-3(4H)-quinazolinyl)propanamide::N-(3-cyano-4,5-diphenyl-furan-2-yl)-3-(4-oxidanylidenequinazolin-3-yl)propanamide::N-(3-cyano-4,5-diphenylfuran-2-yl)-3-(4-oxoquinazolin-3-yl)propanamide::SMR000079099::cid_2220148 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113908&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2220148 252663439 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235635 ClCCc1ccc(cc1)S(=O)(=O)NNC(=O)C(=O)NNc1ccccc1 InChI=1S/C16H17ClN4O4S/c17-11-10-12-6-8-14(9-7-12)26(24,25)21-20-16(23)15(22)19-18-13-4-2-1-3-5-13/h1-9,18,21H,10-11H2,(H,19,22)(H,20,23) NJMFPIVCPGHDRJ-UHFFFAOYSA-N 113909 2-N'-[4-(2-chloroethyl)phenyl]sulfonyl-1-N'-phenylethanedihydrazide::MLS000777456::N2'-[4-(2-chloroethyl)phenyl]sulfonyl-N1'-phenyl-ethanedihydrazide::N2'-[4-(2-chloroethyl)phenyl]sulfonyl-N1'-phenyl-oxalohydrazide::N2'-[4-(2-chloroethyl)phenyl]sulfonyl-N1'-phenylethanedihydrazide::SMR000413850::cid_5187767 Disintegrin and metalloproteinase domain-containing protein 17 27019 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113909&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5187767 252663440 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235636 CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)Nc1ccc(CNC(=O)OC(C)(C)C)cc1)C(=O)OC(C)(C)C InChI=1S/C27H39N5O6/c1-16(2)13-19(24(35)37-26(3,4)5)32-23(34)21-20(29-15-30-21)22(33)31-18-11-9-17(10-12-18)14-28-25(36)38-27(6,7)8/h9-12,15-16,19H,13-14H2,1-8H3,(H,28,36)(H,29,30)(H,31,33)(H,32,34)/t19-/m0/s1 SSDQOVPZUQVMJA-IBGZPJMESA-N 113910 (2S)-2-[[4-[[4-[(tert-butoxycarbonylamino)methyl]phenyl]carbamoyl]-1H-imidazole-5-carbonyl]amino]-4-methyl-valeric acid tert-butyl ester::(2S)-4-methyl-2-[[[4-[[4-[[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]methyl]anilino]-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]pentanoic acid tert-butyl ester::ILP-IV-64::MLS000849611::SMR000465902::cid_16746595::tert-butyl (2S)-4-methyl-2-[[4-[[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]carbamoyl]-1H-imidazol-5-yl]carbonylamino]pentanoate::tert-butyl (2S)-4-methyl-2-[[4-[[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]carbamoyl]-1H-imidazole-5-carbonyl]amino]pentanoate Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113910&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16746595 252663441 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235637 Cc1ccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1 InChI=1S/C27H39N5O6/c1-17-11-13-18(14-12-17)31-22(33)20-21(30-16-29-20)23(34)32-19(24(35)37-26(2,3)4)10-8-9-15-28-25(36)38-27(5,6)7/h11-14,16,19H,8-10,15H2,1-7H3,(H,28,36)(H,29,30)(H,31,33)(H,32,34)/t19-/m0/s1 VDBHGVMULPMSSJ-IBGZPJMESA-N 53413 (2S)-2-[[[4-[(4-methylanilino)-oxomethyl]-1H-imidazol-5-yl]-oxomethyl]amino]-6-[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]hexanoic acid tert-butyl ester::(2S)-6-(tert-butoxycarbonylamino)-2-[[4-(p-tolylcarbamoyl)-1H-imidazole-5-carbonyl]amino]hexanoic acid tert-butyl ester::ILP-IV-50::Isatin, 1::MLS000849601::SMR000465892::cid_16746604::tert-butyl (2S)-2-[[4-[(4-methylphenyl)carbamoyl]-1H-imidazol-5-yl]carbonylamino]-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate::tert-butyl (2S)-2-[[4-[(4-methylphenyl)carbamoyl]-1H-imidazole-5-carbonyl]amino]-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53413&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16746604 123080230 ZINC15952253 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235638 Cc1cccc(c1)[C@@H]1[C@H]2[C@H](C(=O)N(Cc3ccccc3)C2=O)[C@@]2(Cc3ccccc3)N1C(=O)N(C2=O)c1ccc(cc1)C(F)(F)F InChI=1S/C36H28F3N3O4/c1-22-9-8-14-25(19-22)30-28-29(32(44)40(31(28)43)21-24-12-6-3-7-13-24)35(20-23-10-4-2-5-11-23)33(45)41(34(46)42(30)35)27-17-15-26(16-18-27)36(37,38)39/h2-19,28-30H,20-21H2,1H3/t28-,29-,30-,35-/m1/s1 DCARMJBOSRCRIC-UFEGOGPBSA-N 113911 (5S,5aR,8aS,8bR)-5-(3-methylphenyl)-7,8b-bis(phenylmethyl)-2-[4-(trifluoromethyl)phenyl]-5a,8a-dihydro-5H-pyrrolo[1,2]pyrrolo[4,5-a]imidazole-1,3,6,8-tetrone::(5S,5aR,8aS,8bR)-7,8b-dibenzyl-5-(3-methylphenyl)-2-[4-(trifluoromethyl)phenyl]-5a,8a-dihydro-5H-pyrrolo[1,2]pyrrolo[4,5-a]imidazole-1,3,6,8-tetrone::(5S,5aR,8aS,8bR)-7,8b-dibenzyl-5-(m-tolyl)-2-[4-(trifluoromethyl)phenyl]-5a,8a-dihydro-5H-pyrrolo[1,2]pyrrol[4,5-a]imidazole-1,3,6,8-diquinone::MLS001074997::SMR000471063::cid_23641045 Disintegrin and metalloproteinase domain-containing protein 17 69555 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113911&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23641045 252663442 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235639 CC(C)(C)c1ccc(cc1)-c1cc(n[nH]1)-c1ccccc1O InChI=1S/C19H20N2O/c1-19(2,3)14-10-8-13(9-11-14)16-12-17(21-20-16)15-6-4-5-7-18(15)22/h4-12,22H,1-3H3,(H,20,21) GKFUWGIKXZPLAX-UHFFFAOYSA-N 64019 (6E)-6-[5-(4-tert-butylphenyl)-1,2-dihydropyrazol-3-ylidene]-1-cyclohexa-2,4-dienone::(6E)-6-[5-(4-tert-butylphenyl)-1,2-dihydropyrazol-3-ylidene]cyclohexa-2,4-dien-1-one::(6E)-6-[5-(4-tert-butylphenyl)-3-pyrazolin-3-ylidene]cyclohexa-2,4-dien-1-one::2-[5-(4-tert-Butyl-phenyl)-1H-pyrazol-3-yl]-phenol::MLS001202724::SMR000516048::cid_6614263 Disintegrin and metalloproteinase domain-containing protein 17 69555 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=64019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=64019&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6614263 252643118 ZINC13118862 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235640 CCOc1ccc(NC(=O)c2ccc(CN3CCc4ccccc4C3)cc2)cc1 InChI=1S/C25H26N2O2/c1-2-29-24-13-11-23(12-14-24)26-25(28)21-9-7-19(8-10-21)17-27-16-15-20-5-3-4-6-22(20)18-27/h3-14H,2,15-18H2,1H3,(H,26,28) BRYSGTDRSIOCPS-UHFFFAOYSA-N 59544 4-(3,4-Dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-ethoxy-phenyl)-benzamide::4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-(4-ethoxyphenyl)benzamide::4-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-N-p-phenetyl-benzamide::MLS001211849::SMR000515367::cid_1106360 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=59544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=59544&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1106360 252639179 ZINC19770397 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235641 COc1ccccc1Nc1ccc(NC(=O)c2cccc(c2C)[N+]([O-])=O)cc1 InChI=1S/C21H19N3O4/c1-14-17(6-5-8-19(14)24(26)27)21(25)23-16-12-10-15(11-13-16)22-18-7-3-4-9-20(18)28-2/h3-13,22H,1-2H3,(H,23,25) RXWZJIBNGCLNSM-UHFFFAOYSA-N 113912 2-methyl-3-nitro-N-[4-(o-anisidino)phenyl]benzamide::MLS001176133::N-[4-(2-methoxyanilino)phenyl]-2-methyl-3-nitrobenzamide::N-[4-[(2-methoxyphenyl)amino]phenyl]-2-methyl-3-nitro-benzamide::SMR000588236::cid_3930992 Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113912&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3930992 252663443 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235642 CC(C)(C)OC(=O)NCc1ccc(CNC(=O)c2nc[nH]c2C(=O)N[C@@H](Cc2ccccc2)C(=O)OC(C)(C)C)cc1 InChI=1S/C31H39N5O6/c1-30(2,3)41-28(39)23(16-20-10-8-7-9-11-20)36-27(38)25-24(34-19-35-25)26(37)32-17-21-12-14-22(15-13-21)18-33-29(40)42-31(4,5)6/h7-15,19,23H,16-18H2,1-6H3,(H,32,37)(H,33,40)(H,34,35)(H,36,38)/t23-/m0/s1 OFVPTQYHBSAEHG-QHCPKHFHSA-N 113913 (2S)-2-[[5-[[4-[(tert-butoxycarbonylamino)methyl]benzyl]carbamoyl]-1H-imidazole-4-carbonyl]amino]-3-phenyl-propionic acid tert-butyl ester::(2S)-2-[[[5-[[[4-[[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]methyl]phenyl]methylamino]-oxomethyl]-1H-imidazol-4-yl]-oxomethyl]amino]-3-phenylpropanoic acid tert-butyl ester::ILP-I-64::MLS000911289::SMR000641969::cid_24789481::tert-butyl (2S)-2-[[5-[[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]methylcarbamoyl]-1H-imidazol-4-yl]carbonylamino]-3-phenyl-propanoate::tert-butyl (2S)-2-[[5-[[4-[[(2-methylpropan-2-yl)oxycarbonylamino]methyl]phenyl]methylcarbamoyl]-1H-imidazole-4-carbonyl]amino]-3-phenylpropanoate Disintegrin and metalloproteinase domain-containing protein 17 69505 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113913&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24789481 252663444 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235643 COc1cccc(c1)C(=O)NNC(=O)C(=O)Nc1ccc(C)c(Cl)c1 InChI=1S/C17H16ClN3O4/c1-10-6-7-12(9-14(10)18)19-16(23)17(24)21-20-15(22)11-4-3-5-13(8-11)25-2/h3-9H,1-2H3,(H,19,23)(H,20,22)(H,21,24) WSIIRBQCPVISIB-UHFFFAOYSA-N 113914 MLS001219982::N-(3-Chloro-4-methyl-phenyl)-2-[N'-(3-methoxy-benzoyl)-hydrazino]-2-oxo-acetamide::N-(3-chloranyl-4-methyl-phenyl)-2-[2-(3-methoxyphenyl)carbonylhydrazinyl]-2-oxidanylidene-ethanamide::N-(3-chloro-4-methyl-phenyl)-2-keto-2-(N'-m-anisoylhydrazino)acetamide::N-(3-chloro-4-methylphenyl)-2-[2-(3-methoxybenzoyl)hydrazinyl]-2-oxoacetamide::N-(3-chloro-4-methylphenyl)-2-[[(3-methoxyphenyl)-oxomethyl]hydrazo]-2-oxoacetamide::SMR000608112::cid_3117694 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113914&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3117694 252663445 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235644 Cc1ccc(C)c(c1)S(=O)(=O)N1CCC(CC1)c1nc2n(Cc3ccc4OCCOc4c3)nnc2c(=O)[nH]1 InChI=1S/C26H28N6O5S/c1-16-3-4-17(2)22(13-16)38(34,35)31-9-7-19(8-10-31)24-27-25-23(26(33)28-24)29-30-32(25)15-18-5-6-20-21(14-18)37-12-11-36-20/h3-6,13-14,19H,7-12,15H2,1-2H3,(H,27,28,33) ZHPRUXODMBNNFB-UHFFFAOYSA-N 113915 3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-5-[1-(2,5-dimethylphenyl)sulfonyl-4-piperidinyl]-2H-triazolo[4,5-d]pyrimidin-7-one::3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-5-[1-(2,5-dimethylphenyl)sulfonyl-4-piperidyl]-2H-triazolo[4,5-d]pyrimidin-7-one::3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-5-[1-(2,5-dimethylphenyl)sulfonylpiperidin-4-yl]-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one::3-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-5-[1-(2,5-dimethylphenyl)sulfonylpiperidin-4-yl]-2H-triazolo[4,5-d]pyrimidin-7-one::MLS001116323::SMR000625647::cid_23605713 Disintegrin and metalloproteinase domain-containing protein 17 69507 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113915&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23605713 252663446 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235645 COc1ccc(cc1)-c1nnc(SCC(=O)Nc2cc(ccc2Cl)S(=O)(=O)N2CCCCC2)n1N InChI=1S/C22H25ClN6O4S2/c1-33-16-7-5-15(6-8-16)21-26-27-22(29(21)24)34-14-20(30)25-19-13-17(9-10-18(19)23)35(31,32)28-11-3-2-4-12-28/h5-10,13H,2-4,11-12,14,24H2,1H3,(H,25,30) VVRDVFKJMDCXEO-UHFFFAOYSA-N 53851 2-[[4-amino-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-chloro-5-piperidin-1-ylsulfonylphenyl)acetamide::2-[[4-amino-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-(2-chloro-5-piperidinosulfonyl-phenyl)acetamide::2-[[4-amino-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-[2-chloro-5-(1-piperidinylsulfonyl)phenyl]acetamide::2-[[4-azanyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(2-chloranyl-5-piperidin-1-ylsulfonyl-phenyl)ethanamide::MLS000416534::SMR000243460::cid_4968744 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53851&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4968744 252633887 ZINC12818258 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235646 COc1ccc(cc1)C(=O)N\N=C\c1ccc(OC)c(COc2ccccc2)c1 InChI=1S/C23H22N2O4/c1-27-20-11-9-18(10-12-20)23(26)25-24-15-17-8-13-22(28-2)19(14-17)16-29-21-6-4-3-5-7-21/h3-15H,16H2,1-2H3,(H,25,26)/b24-15+ DKQDIBFZSZQGCC-BUVRLJJBSA-N 113916 4-methoxy-N-[(E)-[4-methoxy-3-(phenoxymethyl)benzylidene]amino]benzamide::4-methoxy-N-[(E)-[4-methoxy-3-(phenoxymethyl)phenyl]methylideneamino]benzamide::MLS001223934::SMR000678709::cid_25237158 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113916&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25237158 252663447 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235647 CC(C)c1c(nnn1-c1nonc1N)C(=O)N\N=C\c1cccc2ccccc12 InChI=1S/C19H18N8O2/c1-11(2)16-15(22-26-27(16)18-17(20)24-29-25-18)19(28)23-21-10-13-8-5-7-12-6-3-4-9-14(12)13/h3-11H,1-2H3,(H2,20,24)(H,23,28)/b21-10+ HVUYNDDPSUNKLB-UFFVCSGVSA-N 113917 1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-1-naphthalenylmethylideneamino]-5-propan-2-yl-4-triazolecarboxamide::1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-naphthalen-1-ylmethylideneamino]-5-propan-2-yltriazole-4-carboxamide::1-(4-aminofurazan-3-yl)-5-isopropyl-N-[(E)-1-naphthylmethyleneamino]triazole-4-carboxamide::1-(4-azanyl-1,2,5-oxadiazol-3-yl)-N-[(E)-naphthalen-1-ylmethylideneamino]-5-propan-2-yl-1,2,3-triazole-4-carboxamide::MLS001139382::SMR000647170::cid_6887136 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6887136 252663448 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235648 COc1ccc(C)c2sc(nc12)N(CCCN(C)C)C(=O)c1ccc(cc1)S(=O)(=O)N1CCc2ccccc2C1 InChI=1S/C30H34N4O4S2/c1-21-10-15-26(38-4)27-28(21)39-30(31-27)34(18-7-17-32(2)3)29(35)23-11-13-25(14-12-23)40(36,37)33-19-16-22-8-5-6-9-24(22)20-33/h5-6,8-15H,7,16-20H2,1-4H3 OESJHZIJTQVTCK-UHFFFAOYSA-N 113918 4-(3,4-dihydro-1H-isoquinolin-2-ylsulfonyl)-N-[3-(dimethylamino)propyl]-N-(4-methoxy-7-methyl-1,3-benzothiazol-2-yl)benzamide;hydrochloride::MLS001239190::SMR000807897::cid_24892208 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113918&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24892209 252663449 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235649 COc1ccc(-c2n[nH]c(c2-c2cc3ccccc3o2)C(F)(F)F)c(O)c1 InChI=1S/C19H13F3N2O3/c1-26-11-6-7-12(13(25)9-11)17-16(18(24-23-17)19(20,21)22)15-8-10-4-2-3-5-14(10)27-15/h2-9,25H,1H3,(H,23,24) LWKCIPORVGAZTO-UHFFFAOYSA-N 53537 (6E)-6-[4-(1-benzofuran-2-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]-3-methoxy-cyclohexa-2,4-dien-1-one::(6E)-6-[4-(1-benzofuran-2-yl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]-3-methoxycyclohexa-2,4-dien-1-one::(6E)-6-[4-(2-benzofuranyl)-5-(trifluoromethyl)-1,2-dihydropyrazol-3-ylidene]-3-methoxy-1-cyclohexa-2,4-dienone::(6E)-6-[4-(benzofuran-2-yl)-5-(trifluoromethyl)-3-pyrazolin-3-ylidene]-3-methoxy-cyclohexa-2,4-dien-1-one::MLS000097992::SMR000060635::cid_5742541 Disintegrin and metalloproteinase domain-containing protein 17 69479 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=53537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=53537&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5742541 252633581 ZINC12476696 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235650 O=C(C1CCC(Cn2c(=S)[nH]c3ccccc3c2=O)CC1)N1CCN(CC1)c1ccccc1 InChI=1S/C26H30N4O2S/c31-24(29-16-14-28(15-17-29)21-6-2-1-3-7-21)20-12-10-19(11-13-20)18-30-25(32)22-8-4-5-9-23(22)27-26(30)33/h1-9,19-20H,10-18H2,(H,27,33) LOJWCKAJJWXFDG-UHFFFAOYSA-N 42818 3-({4-[(4-phenyl-1-piperazinyl)carbonyl]cyclohexyl}methyl)-2-thioxo-2,3-dihydro-4(1H)-quinazolinone::3-[[4-(4-phenylpiperazin-1-yl)carbonylcyclohexyl]methyl]-2-sulfanylidene-1H-quinazolin-4-one::3-[[4-(4-phenylpiperazine-1-carbonyl)cyclohexyl]methyl]-2-sulfanylidene-1H-quinazolin-4-one::3-[[4-(4-phenylpiperazine-1-carbonyl)cyclohexyl]methyl]-2-thioxo-1H-quinazolin-4-one::3-[[4-[oxo-(4-phenyl-1-piperazinyl)methyl]cyclohexyl]methyl]-2-sulfanylidene-1H-quinazolin-4-one::MLS000097399::SMR000076048::cid_2952511 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=42818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=42818&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2952511 252623508 ZINC04014305 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235651 O=C1N(NS(=O)(=O)c2ccccc2)C(=S)S\C1=C/c1cccs1 InChI=1S/C14H10N2O3S4/c17-13-12(9-10-5-4-8-21-10)22-14(20)16(13)15-23(18,19)11-6-2-1-3-7-11/h1-9,15H/b12-9- VWAZCVPSBKHJKM-XFXZXTDPSA-N 54124 MLS000778544::N-[(5Z)-4-keto-5-(2-thenylidene)-2-thioxo-thiazolidin-3-yl]benzenesulfonamide::N-[(5Z)-4-oxidanylidene-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-thiazolidin-3-yl]benzenesulfonamide::N-[(5Z)-4-oxo-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-1,3-thiazolidin-3-yl]benzenesulfonamide::N-[(5Z)-4-oxo-2-sulfanylidene-5-(thiophen-2-ylmethylidene)-3-thiazolidinyl]benzenesulfonamide::N-{4-Oxo-5-[1-thiophen-2-yl-meth-(Z)-ylidene]-2-thioxo-thiazolidin-3-yl}-benzenesulfonamide::SMR000415338::cid_2021233 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=54124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=54124&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2021233 252634158 ZINC12803012 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235652 COC(=O)c1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C InChI=1S/C21H16N2O4/c1-23-16(13-8-10-15(11-9-13)21(25)26-2)12-17-18(20(23)24)19(22-27-17)14-6-4-3-5-7-14/h3-12H,1-2H3 IUFFVQQLFWTNOL-UHFFFAOYSA-N 113919 4-(4-keto-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-6-yl)benzoic acid methyl ester::4-(5-methyl-4-oxo-3-phenyl-6-isoxazolo[4,5-c]pyridinyl)benzoic acid methyl ester::MLS002153016::SMR001229078::cid_24983127::methyl 4-(5-methyl-4-oxidanylidene-3-phenyl-[1,2]oxazolo[4,5-c]pyridin-6-yl)benzoate::methyl 4-(5-methyl-4-oxo-3-phenyl-4,5-dihydroisoxazolo[4,5-c]pyridin-6-yl)benzoate::methyl 4-(5-methyl-4-oxo-3-phenyl-[1,2]oxazolo[4,5-c]pyridin-6-yl)benzoate Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113919&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24983127 252663450 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235653 Cc1ccc2c(NC(=O)[C@@]3(C)[C@H]([C@H]4COc5ccccc5[C@@H]4N3C2=O)c2ccccc2)c1 InChI=1S/C27H24N2O3/c1-16-12-13-18-21(14-16)28-26(31)27(2)23(17-8-4-3-5-9-17)20-15-32-22-11-7-6-10-19(22)24(20)29(27)25(18)30/h3-14,20,23-24H,15H2,1-2H3,(H,28,31)/t20-,23+,24+,27-/m1/s1 VGMIFHXFRKOEND-MBPYSEENSA-N 113920 MLS002174171::SMR001261338::cid_25102755 Disintegrin and metalloproteinase domain-containing protein 17 69512 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113920&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25102755 242053883 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235654 COc1cc2NC(=O)[C@@]3(C)[C@H]([C@H]4COc5ccc(Cl)cc5[C@@H]4N3C(=O)c2cc1OC)c1ccccc1 InChI=1S/C28H25ClN2O5/c1-28-24(15-7-5-4-6-8-15)19-14-36-21-10-9-16(29)11-18(21)25(19)31(28)26(32)17-12-22(34-2)23(35-3)13-20(17)30-27(28)33/h4-13,19,24-25H,14H2,1-3H3,(H,30,33)/t19-,24+,25+,28-/m1/s1 ZSCSQJZCEGHEIP-XCKQOEPASA-N 113921 MLS002174230::SMR001261397::cid_25102765 Disintegrin and metalloproteinase domain-containing protein 17 69503 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113921 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113921&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25102765 242053884 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235655 CCc1cc(Cn2nc(cc2C(=O)NCc2cccc(Br)c2)-c2ccccc2)on1 InChI=1S/C23H21BrN4O2/c1-2-19-12-20(30-27-19)15-28-22(13-21(26-28)17-8-4-3-5-9-17)23(29)25-14-16-7-6-10-18(24)11-16/h3-13H,2,14-15H2,1H3,(H,25,29) LTYZBYSGJAJZMU-UHFFFAOYSA-N 76246 MLS001143266::N-(3-bromobenzyl)-2-[(3-ethylisoxazol-5-yl)methyl]-5-phenyl-pyrazole-3-carboxamide::N-[(3-bromophenyl)methyl]-2-[(3-ethyl-1,2-oxazol-5-yl)methyl]-5-phenyl-pyrazole-3-carboxamide::N-[(3-bromophenyl)methyl]-2-[(3-ethyl-1,2-oxazol-5-yl)methyl]-5-phenylpyrazole-3-carboxamide::N-[(3-bromophenyl)methyl]-2-[(3-ethyl-5-isoxazolyl)methyl]-5-phenyl-3-pyrazolecarboxamide::SMR001227318::cid_42601127 Disintegrin and metalloproteinase domain-containing protein 17 69507 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=76246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=76246&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 42601127 252653426 ZINC61959512 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235656 COc1ccc(CN([C@H](CO)CC(C)C)S(=O)(=O)N(Cc2ccccc2)[C@H](CO)CC(C)C)cc1 InChI=1S/C27H42N2O5S/c1-21(2)15-25(19-30)28(17-23-9-7-6-8-10-23)35(32,33)29(26(20-31)16-22(3)4)18-24-11-13-27(34-5)14-12-24/h6-14,21-22,25-26,30-31H,15-20H2,1-5H3/t25-,26-/m0/s1 DLXJQCWKXYFUBB-UIOOFZCWSA-N 113922 (2S)-2-[[(4-methoxyphenyl)methyl-[(2S)-4-methyl-1-oxidanyl-pentan-2-yl]sulfamoyl]-(phenylmethyl)amino]-4-methyl-pentan-1-ol::(2S)-2-[[[(2S)-1-hydroxy-4-methylpentan-2-yl]-[(4-methoxyphenyl)methyl]sulfamoyl]-(phenylmethyl)amino]-4-methyl-1-pentanol::(2S)-2-[benzyl-[[(1S)-3-methyl-1-methylol-butyl]-p-anisyl-sulfamoyl]amino]-4-methyl-pentan-1-ol::(2S)-2-[benzyl-[[(2S)-1-hydroxy-4-methylpentan-2-yl]-[(4-methoxyphenyl)methyl]sulfamoyl]amino]-4-methylpentan-1-ol::MLS002240575::SMR001308243::cid_42628464 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113922&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 42628464 252663451 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235657 COC(=O)[C@H](CCCCNC(=O)OC(C)(C)C)n1cc(nn1)-c1cc(cc(c1)-c1cn(nn1)[C@@H](Cc1c[nH]c2ccccc12)C(=O)OC)C(=O)N1CCN(CC1)C(=O)OC(C)(C)C InChI=1S/C44H56N10O9/c1-43(2,3)62-41(58)45-16-12-11-15-36(39(56)60-7)53-26-34(47-49-53)28-21-29(23-30(22-28)38(55)51-17-19-52(20-18-51)42(59)63-44(4,5)6)35-27-54(50-48-35)37(40(57)61-8)24-31-25-46-33-14-10-9-13-32(31)33/h9-10,13-14,21-23,25-27,36-37,46H,11-12,15-20,24H2,1-8H3,(H,45,58)/t36-,37-/m0/s1 YVTYHXDYHXEWPH-BCRBLDSWSA-N 113923 LU-MONO-WK::MLS002280542::SMR000327500::cid_16066583 Disintegrin and metalloproteinase domain-containing protein 17 69511 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113923&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16066583 242053885 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235658 COC(=O)C1=C(C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(cc1)C(C)(C)C)c1ccccc1OCc1ccccc1 InChI=1S/C34H38N2O4/c1-34(2,3)25-16-14-23(15-17-25)21-35-33(38)36-26-18-19-29(36)31(32(37)39-4)28(20-26)27-12-8-9-13-30(27)40-22-24-10-6-5-7-11-24/h5-17,26,29H,18-22H2,1-4H3,(H,35,38)/t26-,29+/m0/s1 QSUJAQNGLQUEEC-LITSAYRRSA-N 113924 (1S,5R)-3-(2-benzoxyphenyl)-8-[(4-tert-butylbenzyl)carbamoyl]-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::(1S,5R)-8-[[(4-tert-butylphenyl)methylamino]-oxomethyl]-3-(2-phenylmethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylic acid methyl ester::MLS002472187::SMR001395338::cid_44144111::methyl (1S,5R)-8-[(4-tert-butylphenyl)methylcarbamoyl]-3-(2-phenylmethoxyphenyl)-8-azabicyclo[3.2.1]oct-3-ene-4-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113924&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44144111 252663452 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235659 CC1(C)Oc2ccc3C[C@H](COc3c2C=C1)c1ccc(O)cc1O InChI=1S/C20H20O4/c1-20(2)8-7-16-18(24-20)6-3-12-9-13(11-23-19(12)16)15-5-4-14(21)10-17(15)22/h3-8,10,13,21-22H,9,11H2,1-2H3/t13-/m1/s1 LBQIJVLKGVZRIW-CYBMUJFWSA-N 113925 4-[(3S)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f][1]benzopyran-3-yl]benzene-1,3-diol::4-[(3S)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol::4-[(3S)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f]chromen-3-yl]resorcinol::Glabridin::MLS002473046::SMR001397150::cid_44144325 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113925 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113925&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44144325 252663453 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235660 OCCN(Cc1ccccc1)C(=O)C[C@H](CC=C)C(=O)N[C@@H](COC(=O)[C@H](CCC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C40H46FN3O5/c1-3-5-14-32(23-29-17-19-34(41)20-18-29)40(48)49-28-35(24-33-26-42-37-16-10-9-15-36(33)37)43-39(47)31(11-4-2)25-38(46)44(21-22-45)27-30-12-7-6-8-13-30/h3-4,6-10,12-13,15-20,26,31-32,35,42,45H,1-2,5,11,14,21-25,27-28H2,(H,43,47)/t31-,32+,35+/m0/s1 PVEHXQZUOGFZJL-GTXBZULCSA-N 113926 (2R)-2-(4-fluorobenzyl)hex-5-enoic acid [(2R)-2-[[(2S)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2R)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2R)-2-[[(2S)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002319855::SMR001337479::[(2R)-2-[[(2S)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2R)-2-[[(2S)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201427 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113926&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201427 252663454 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235661 OCCN(Cc1ccccc1)C(=O)C[C@H](CC=C)C(=O)N[C@H](COC(=O)[C@@H](CC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C39H44FN3O5/c1-3-10-30(24-37(45)43(20-21-44)26-29-12-6-5-7-13-29)38(46)42-34(23-32-25-41-36-15-9-8-14-35(32)36)27-48-39(47)31(11-4-2)22-28-16-18-33(40)19-17-28/h3-9,12-19,25,30-31,34,41,44H,1-2,10-11,20-24,26-27H2,(H,42,46)/t30-,31-,34-/m0/s1 ZNYWUZSKWNOBHB-JHFJJOSTSA-N 113927 (2S)-2-(4-fluorobenzyl)pent-4-enoic acid [(2S)-2-[[(2S)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2S)-2-[(4-fluorophenyl)methyl]-4-pentenoic acid [(2S)-2-[[(2S)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002319859::SMR001337483::[(2S)-2-[[(2S)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2S)-2-[(4-fluorophenyl)methyl]pent-4-enoate::[(2S)-2-[[(2S)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2S)-2-[(4-fluorophenyl)methyl]pent-4-enoate::cid_44201431 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113927&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201431 252663455 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235662 OCCN(Cc1ccccc1)C(=O)C[C@@H](CC=C)C(=O)N[C@H](COC(=O)[C@@H](CCC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C40H46FN3O5/c1-3-5-14-32(23-29-17-19-34(41)20-18-29)40(48)49-28-35(24-33-26-42-37-16-10-9-15-36(33)37)43-39(47)31(11-4-2)25-38(46)44(21-22-45)27-30-12-7-6-8-13-30/h3-4,6-10,12-13,15-20,26,31-32,35,42,45H,1-2,5,11,14,21-25,27-28H2,(H,43,47)/t31-,32+,35+/m1/s1 PVEHXQZUOGFZJL-RASJINCSSA-N 113928 (2S)-2-(4-fluorobenzyl)hex-5-enoic acid [(2S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2S)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002319865::SMR001337489::[(2S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201437 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113928&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201437 252663456 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235663 OCCN(Cc1ccccc1)C(=O)C[C@@H](CC=C)C(=O)NC[C@@H](OC(=O)[C@@H](CCC=C)Cc1ccc(F)cc1)c1ccccc1 InChI=1S/C37H43FN2O5/c1-3-5-15-32(24-28-18-20-33(38)21-19-28)37(44)45-34(30-16-10-7-11-17-30)26-39-36(43)31(12-4-2)25-35(42)40(22-23-41)27-29-13-8-6-9-14-29/h3-4,6-11,13-14,16-21,31-32,34,41H,1-2,5,12,15,22-27H2,(H,39,43)/t31-,32+,34-/m1/s1 NOPBTFLPWKCWON-HWIYEDSRSA-N 113929 (2S)-2-(4-fluorobenzyl)hex-5-enoic acid [(1S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-1-phenyl-ethyl] ester::(2S)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(1S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-1-phenylethyl] ester::MLS002319902::SMR001337526::[(1S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-1-phenyl-ethyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(1S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-1-phenylethyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201473 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113929&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201473 252663457 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235664 OCCN(Cc1ccccc1)C(=O)C[C@@H](CC=C)C(=O)N[C@H](COC(=O)[C@@H](CCC=C)Cc1ccc(F)cc1)c1ccccc1 InChI=1S/C37H43FN2O5/c1-3-5-15-32(24-28-18-20-33(38)21-19-28)37(44)45-27-34(30-16-10-7-11-17-30)39-36(43)31(12-4-2)25-35(42)40(22-23-41)26-29-13-8-6-9-14-29/h3-4,6-11,13-14,16-21,31-32,34,41H,1-2,5,12,15,22-27H2,(H,39,43)/t31-,32+,34-/m1/s1 DJCLHRXNACSRHI-HWIYEDSRSA-N 113930 (2S)-2-(4-fluorobenzyl)hex-5-enoic acid [(2S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-2-phenyl-ethyl] ester::(2S)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-2-phenylethyl] ester::MLS002319947::SMR001337571::[(2S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-2-phenyl-ethyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-2-phenylethyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201515 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113930&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201515 252663458 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235665 OCCN(Cc1ccccc1)C(=O)C[C@@H](CC=C)C(=O)N[C@H](COC(=O)[C@H](CCC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C40H46FN3O5/c1-3-5-14-32(23-29-17-19-34(41)20-18-29)40(48)49-28-35(24-33-26-42-37-16-10-9-15-36(33)37)43-39(47)31(11-4-2)25-38(46)44(21-22-45)27-30-12-7-6-8-13-30/h3-4,6-10,12-13,15-20,26,31-32,35,42,45H,1-2,5,11,14,21-25,27-28H2,(H,43,47)/t31-,32-,35+/m1/s1 PVEHXQZUOGFZJL-FAJRIDIVSA-N 113931 (2R)-2-(4-fluorobenzyl)hex-5-enoic acid [(2S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2R)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002320303::SMR001337928::[(2S)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2S)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201804 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113931&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201804 252663459 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235666 OCCN(Cc1ccccc1)C(=O)C[C@@H](CC=C)C(=O)N[C@@H](COC(=O)[C@H](CCC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C40H46FN3O5/c1-3-5-14-32(23-29-17-19-34(41)20-18-29)40(48)49-28-35(24-33-26-42-37-16-10-9-15-36(33)37)43-39(47)31(11-4-2)25-38(46)44(21-22-45)27-30-12-7-6-8-13-30/h3-4,6-10,12-13,15-20,26,31-32,35,42,45H,1-2,5,11,14,21-25,27-28H2,(H,43,47)/t31-,32-,35-/m1/s1 PVEHXQZUOGFZJL-ZGJMHZNISA-N 113932 (2R)-2-(4-fluorobenzyl)hex-5-enoic acid [(2R)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2R)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2R)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002320326::SMR001337951::[(2R)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2R)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201827 Disintegrin and metalloproteinase domain-containing protein 17 69491 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113932&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201827 252663460 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235667 OC[C@H](Cc1ccccc1)NC(=O)C[C@H](CC=C)C(=O)N[C@H](COC(=O)[C@H](CCC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C40H46FN3O5/c1-3-5-14-31(21-29-17-19-33(41)20-18-29)40(48)49-27-35(23-32-25-42-37-16-10-9-15-36(32)37)44-39(47)30(11-4-2)24-38(46)43-34(26-45)22-28-12-7-6-8-13-28/h3-4,6-10,12-13,15-20,25,30-31,34-35,42,45H,1-2,5,11,14,21-24,26-27H2,(H,43,46)(H,44,47)/t30-,31+,34-,35-/m0/s1 NVFBPXDALITKAR-GXFPKFJOSA-N 113933 (2R)-2-(4-fluorobenzyl)hex-5-enoic acid [(2S)-2-[[(2S)-2-[2-[[(1S)-1-benzyl-2-hydroxy-ethyl]amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2R)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2S)-2-[[(2S)-2-[2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002320341::SMR001337966::[(2S)-2-[[(2S)-2-[2-[[(2S)-1-hydroxy-3-phenylpropan-2-yl]amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2S)-3-(1H-indol-3-yl)-2-[[(2S)-2-[2-oxidanylidene-2-[[(2S)-1-oxidanyl-3-phenyl-propan-2-yl]amino]ethyl]pent-4-enoyl]amino]propyl] (2R)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201842 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113933&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201842 252663461 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235668 OCCN(Cc1ccccc1)C(=O)C[C@@H](CC=C)C(=O)N[C@@H](COC(=O)[C@@H](CCC=C)Cc1ccc(F)cc1)Cc1c[nH]c2ccccc12 InChI=1S/C40H46FN3O5/c1-3-5-14-32(23-29-17-19-34(41)20-18-29)40(48)49-28-35(24-33-26-42-37-16-10-9-15-36(33)37)43-39(47)31(11-4-2)25-38(46)44(21-22-45)27-30-12-7-6-8-13-30/h3-4,6-10,12-13,15-20,26,31-32,35,42,45H,1-2,5,11,14,21-25,27-28H2,(H,43,47)/t31-,32+,35-/m1/s1 PVEHXQZUOGFZJL-MEEYNGGZSA-N 113934 (2S)-2-(4-fluorobenzyl)hex-5-enoic acid [(2R)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-keto-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] ester::(2S)-2-[(4-fluorophenyl)methyl]-5-hexenoic acid [(2R)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxoethyl]-1-oxopent-4-enyl]amino]-3-(1H-indol-3-yl)propyl] ester::MLS002320352::SMR001337977::[(2R)-2-[[(2R)-2-[2-[2-hydroxyethyl-(phenylmethyl)amino]-2-oxidanylidene-ethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::[(2R)-2-[[(2R)-2-[2-[benzyl(2-hydroxyethyl)amino]-2-oxoethyl]pent-4-enoyl]amino]-3-(1H-indol-3-yl)propyl] (2S)-2-[(4-fluorophenyl)methyl]hex-5-enoate::cid_44201852 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113934&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201852 252663462 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235669 C[C@@H](CO)N1C[C@@H](C)[C@@H](CN(C)Cc2ccc(Oc3ccccc3)cc2)Oc2ccc(NC(=O)Nc3ccc(F)cc3)cc2C1=O InChI=1S/C36H39FN4O5/c1-24-20-41(25(2)23-42)35(43)32-19-29(39-36(44)38-28-13-11-27(37)12-14-28)15-18-33(32)46-34(24)22-40(3)21-26-9-16-31(17-10-26)45-30-7-5-4-6-8-30/h4-19,24-25,34,42H,20-23H2,1-3H3,(H2,38,39,44)/t24-,25+,34-/m1/s1 NOWHXTYRWKQEBH-RDXDNIQESA-N 113935 1-(4-fluorophenyl)-3-[(2S,3R)-3-methyl-2-[[methyl-[(4-phenoxyphenyl)methyl]amino]methyl]-6-oxidanylidene-5-[(2S)-1-oxidanylpropan-2-yl]-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]urea::1-(4-fluorophenyl)-3-[(2S,3R)-5-[(1S)-2-hydroxy-1-methyl-ethyl]-6-keto-3-methyl-2-[[methyl-(4-phenoxybenzyl)amino]methyl]-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]urea::1-(4-fluorophenyl)-3-[(2S,3R)-5-[(2S)-1-hydroxypropan-2-yl]-3-methyl-2-[[methyl-[(4-phenoxyphenyl)methyl]amino]methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-8-yl]urea::MLS002474342::SMR001398503::cid_44201997 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113935 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113935&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44201997 252663463 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235670 COc1ccccc1NS(=O)(=O)c1cc(NC(=O)c2cc(F)c(F)c(F)c2F)ccc1N1CCOCC1 InChI=1S/C24H21F4N3O5S/c1-35-19-5-3-2-4-17(19)30-37(33,34)20-12-14(6-7-18(20)31-8-10-36-11-9-31)29-24(32)15-13-16(25)22(27)23(28)21(15)26/h2-7,12-13,30H,8-11H2,1H3,(H,29,32) KQZOJGVATWUJAM-UHFFFAOYSA-N 113936 2,3,4,5-tetrafluoro-N-[3-[(2-methoxyphenyl)sulfamoyl]-4-(4-morpholinyl)phenyl]benzamide::2,3,4,5-tetrafluoro-N-[3-[(2-methoxyphenyl)sulfamoyl]-4-morpholin-4-ylphenyl]benzamide::2,3,4,5-tetrafluoro-N-[3-[(2-methoxyphenyl)sulfamoyl]-4-morpholino-phenyl]benzamide::2,3,4,5-tetrakis(fluoranyl)-N-[3-[(2-methoxyphenyl)sulfamoyl]-4-morpholin-4-yl-phenyl]benzamide::MLS002248444::SMR001315914::cid_5216904 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113936&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5216904 252663464 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235671 [O-][N+](=O)c1ccc(cc1)[C@@H]1[C-](N[N+](=C1C(=O)N1CCOC1=O)c1ccc(Br)cc1)c1ccc(F)cc1 InChI=1S/C25H18BrFN4O5/c26-17-5-11-19(12-6-17)30-23(24(32)29-13-14-36-25(29)33)21(15-3-9-20(10-4-15)31(34)35)22(28-30)16-1-7-18(27)8-2-16/h1-12,21,28H,13-14H2/t21-/m1/s1 MHRJFXZXLGQFBK-OAQYLSRUSA-N 113937 3-[(3R,4S)-2-(4-bromophenyl)-5-(4-fluorophenyl)-4-(4-nitrophenyl)-2-pyrazoline-3-carbonyl]oxazolidin-2-one::3-[(3R,4S)-2-(4-bromophenyl)-5-(4-fluorophenyl)-4-(4-nitrophenyl)-3,4-dihydropyrazole-3-carbonyl]-1,3-oxazolidin-2-one::3-[[(3R,4S)-2-(4-bromophenyl)-5-(4-fluorophenyl)-4-(4-nitrophenyl)-3,4-dihydropyrazol-3-yl]-oxomethyl]-2-oxazolidinone::3-[[(3R,4S)-2-(4-bromophenyl)-5-(4-fluorophenyl)-4-(4-nitrophenyl)-3,4-dihydropyrazol-3-yl]carbonyl]-1,3-oxazolidin-2-one::MLS000517953::SMR000327285::cid_16060024 Disintegrin and metalloproteinase domain-containing protein 17 69488 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113937&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899702 252663465 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235672 [O-][N+](=O)c1ccc(cc1)[C@@H]1[C-](N[N+](=C1C(=O)N1CCOC1=O)c1ccc(Br)cc1)c1cccc(Cl)c1 InChI=1S/C25H18BrClN4O5/c26-17-6-10-19(11-7-17)30-23(24(32)29-12-13-36-25(29)33)21(15-4-8-20(9-5-15)31(34)35)22(28-30)16-2-1-3-18(27)14-16/h1-11,14,21,28H,12-13H2/t21-/m1/s1 MCGKQDPUWIBNBI-OAQYLSRUSA-N 113938 3-[(3R,4S)-2-(4-bromophenyl)-5-(3-chlorophenyl)-4-(4-nitrophenyl)-2-pyrazoline-3-carbonyl]oxazolidin-2-one::3-[(3R,4S)-2-(4-bromophenyl)-5-(3-chlorophenyl)-4-(4-nitrophenyl)-3,4-dihydropyrazole-3-carbonyl]-1,3-oxazolidin-2-one::3-[[(3R,4S)-2-(4-bromophenyl)-5-(3-chlorophenyl)-4-(4-nitrophenyl)-3,4-dihydropyrazol-3-yl]-oxomethyl]-2-oxazolidinone::3-[[(3R,4S)-2-(4-bromophenyl)-5-(3-chlorophenyl)-4-(4-nitrophenyl)-3,4-dihydropyrazol-3-yl]carbonyl]-1,3-oxazolidin-2-one::MLS000517955::SMR000327279::cid_16060018 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113938 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113938&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91899703 252663466 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235673 COc1ccccc1Oc1c(C)[nH]nc1-c1ccc(OCC(C)=C)cc1O InChI=1S/C21H22N2O4/c1-13(2)12-26-15-9-10-16(17(24)11-15)20-21(14(3)22-23-20)27-19-8-6-5-7-18(19)25-4/h5-11,24H,1,12H2,2-4H3,(H,22,23) SLIGTSUZRAYWEB-UHFFFAOYSA-N 67733 (6E)-6-[4-(2-methoxyphenoxy)-5-methyl-1,2-dihydropyrazol-3-ylidene]-3-(2-methylprop-2-enoxy)-1-cyclohexa-2,4-dienone::(6E)-6-[4-(2-methoxyphenoxy)-5-methyl-1,2-dihydropyrazol-3-ylidene]-3-(2-methylprop-2-enoxy)cyclohexa-2,4-dien-1-one::(6E)-6-[4-(2-methoxyphenoxy)-5-methyl-3-pyrazolin-3-ylidene]-3-(2-methylallyloxy)cyclohexa-2,4-dien-1-one::MLS000083083::SMR000045197::cid_5389819 Disintegrin and metalloproteinase domain-containing protein 17 69479 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=67733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=67733&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5389819 252646023 ZINC18095839 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235674 Cc1ccc(OCC(=O)Nc2nnc[nH]2)c(Br)c1 InChI=1S/C11H11BrN4O2/c1-7-2-3-9(8(12)4-7)18-5-10(17)15-11-13-6-14-16-11/h2-4,6H,5H2,1H3,(H2,13,14,15,16,17) BCIQRCHVOVWEKA-UHFFFAOYSA-N 51400 2-(2-bromanyl-4-methyl-phenoxy)-N-(1H-1,2,4-triazol-5-yl)ethanamide::2-(2-bromo-4-methyl-phenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide::2-(2-bromo-4-methylphenoxy)-N-(1H-1,2,4-triazol-5-yl)acetamide::MLS-0315819.0001::cid_719106 Disintegrin and metalloproteinase domain-containing protein 17 69478 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51400&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 719106 252631601 ZINC13127304 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235675 CC(C)C1Nc2ccc(cc2C2C=CCC12)S(N)(=O)=O InChI=1S/C15H20N2O2S/c1-9(2)15-12-5-3-4-11(12)13-8-10(20(16,18)19)6-7-14(13)17-15/h3-4,6-9,11-12,15,17H,5H2,1-2H3,(H2,16,18,19) QAPGNKVYTHSMMC-UHFFFAOYSA-N 52179 4-isopropyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide::4-propan-2-yl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide::MLS000062075::SMR000070348::cid_2874832 Disintegrin and metalloproteinase domain-containing protein 17 69499 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=52179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=52179&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2874832 252632330 ZINC02271213 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235676 O=C(CC1CCCCC1)Nc1nnc[nH]1 InChI=1S/C10H16N4O/c15-9(13-10-11-7-12-14-10)6-8-4-2-1-3-5-8/h7-8H,1-6H2,(H2,11,12,13,14,15) WOQYWVDZSFPTSS-UHFFFAOYSA-N 51399 2-cyclohexyl-N-(1H-1,2,4-triazol-5-yl)acetamide::2-cyclohexyl-N-(1H-1,2,4-triazol-5-yl)ethanamide::MLS-0072999.0001::cid_704227 Disintegrin and metalloproteinase domain-containing protein 17 69473 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51399&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 704227 252631600 ZINC02418861 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235677 CCN(CC)c1ccc(NC(=O)COC(=O)CSc2ccc(Br)cc2C)cc1 InChI=1S/C21H25BrN2O3S/c1-4-24(5-2)18-9-7-17(8-10-18)23-20(25)13-27-21(26)14-28-19-11-6-16(22)12-15(19)3/h6-12H,4-5,13-14H2,1-3H3,(H,23,25) CTXGONJTLPDCDQ-UHFFFAOYSA-N 113939 2-[(4-bromo-2-methyl-phenyl)thio]acetic acid [2-[4-(diethylamino)anilino]-2-keto-ethyl] ester;sulfuric acid::2-[(4-bromo-2-methylphenyl)thio]acetic acid [2-[4-(diethylamino)anilino]-2-oxoethyl] ester;sulfuric acid::MLS002635793::SMR000263687::[2-[4-(diethylamino)anilino]-2-oxoethyl] 2-(4-bromo-2-methylphenyl)sulfanylacetate;sulfuric acid::[2-[[4-(diethylamino)phenyl]amino]-2-oxidanylidene-ethyl] 2-(4-bromanyl-2-methyl-phenyl)sulfanylethanoate;sulfuric acid::cid_12006230 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113939&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2356440 252663467 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235678 CCn1nc(C(=O)OC(C(=O)c2c[nH]c3ccccc23)c2ccccc2)c2ccccc2c1=O InChI=1S/C27H21N3O4/c1-2-30-26(32)20-14-7-6-13-19(20)23(29-30)27(33)34-25(17-10-4-3-5-11-17)24(31)21-16-28-22-15-9-8-12-18(21)22/h3-16,25,28H,2H2,1H3 UIHGNJALPXKJRE-UHFFFAOYSA-N 113940 3-ethyl-4-keto-phthalazine-1-carboxylic acid [2-(1H-indol-3-yl)-2-keto-1-phenyl-ethyl] ester::3-ethyl-4-oxo-1-phthalazinecarboxylic acid [2-(1H-indol-3-yl)-2-oxo-1-phenylethyl] ester::MLS002634241::SMR000152532::[2-(1H-indol-3-yl)-2-oxidanylidene-1-phenyl-ethyl] 3-ethyl-4-oxidanylidene-phthalazine-1-carboxylate::[2-(1H-indol-3-yl)-2-oxo-1-phenylethyl] 3-ethyl-4-oxophthalazine-1-carboxylate::cid_4003989 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113940&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4003989 252663468 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235679 Clc1cccc2c(Br)ccc(SCC(=O)Nc3ccc(cc3)S(=O)(=O)Nc3nccs3)c12 InChI=1S/C21H15BrClN3O3S3/c22-16-8-9-18(20-15(16)2-1-3-17(20)23)31-12-19(27)25-13-4-6-14(7-5-13)32(28,29)26-21-24-10-11-30-21/h1-11H,12H2,(H,24,26)(H,25,27) LFEWVFGQDZKNAT-UHFFFAOYSA-N 43128 2-(4-bromanyl-8-chloranyl-naphthalen-1-yl)sulfanyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide::2-(4-bromo-8-chloronaphthalen-1-yl)sulfanyl-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide::2-[(4-bromo-8-chloro-1-naphthalenyl)thio]-N-[4-(2-thiazolylsulfamoyl)phenyl]acetamide::2-[(4-bromo-8-chloro-1-naphthyl)thio]-N-[4-(thiazol-2-ylsulfamoyl)phenyl]acetamide::MLS000336743::SMR000244058::cid_2351884 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=43128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=43128&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 2351884 252623812 ZINC03234027 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235680 Oc1c(ccccc1=O)C(=O)\C=C\c1ccc(cc1)[N+]([O-])=O InChI=1S/C16H11NO5/c18-14(13-3-1-2-4-15(19)16(13)20)10-7-11-5-8-12(9-6-11)17(21)22/h1-10H,(H,19,20)/b10-7+ XOEHJLARIPTYHM-JXMROGBWSA-N 100259 2-hydroxy-3-[(E)-3-(4-nitrophenyl)-1-oxoprop-2-enyl]-1-cyclohepta-2,4,6-trienone::2-hydroxy-3-[(E)-3-(4-nitrophenyl)acryloyl]cyclohepta-2,4,6-trien-1-one::2-hydroxy-3-[(E)-3-(4-nitrophenyl)prop-2-enoyl]cyclohepta-2,4,6-trien-1-one::3-[(E)-3-(4-nitrophenyl)prop-2-enoyl]-2-oxidanyl-cyclohepta-2,4,6-trien-1-one::MLS002701851::SMR001565443::cid_6302331 Disintegrin and metalloproteinase domain-containing protein 17 11786 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=100259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=100259&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 6302331 252663343 ZINC17140040 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235681 CC(C)CC1N(Cc2ccc(cc2)-c2c(C)cccc2C)S(=O)(=O)CCN(Cc2cn(CCO)nn2)C1=O InChI=1S/C28H37N5O4S/c1-20(2)16-26-28(35)31(18-25-19-32(12-14-34)30-29-25)13-15-38(36,37)33(26)17-23-8-10-24(11-9-23)27-21(3)6-5-7-22(27)4/h5-11,19-20,26,34H,12-18H2,1-4H3 UVXGGJFEGBCHNS-UHFFFAOYSA-N 113941 2-[4-(2,6-dimethylphenyl)benzyl]-5-[[1-(2-hydroxyethyl)triazol-4-yl]methyl]-3-isobutyl-1,1-diketo-1,2,5-thiadiazepan-4-one::2-[[4-(2,6-dimethylphenyl)phenyl]methyl]-5-[[1-(2-hydroxyethyl)-1,2,3-triazol-4-yl]methyl]-3-(2-methylpropyl)-1,1-bis(oxidanylidene)-1,2,5-thiadiazepan-4-one::2-[[4-(2,6-dimethylphenyl)phenyl]methyl]-5-[[1-(2-hydroxyethyl)-4-triazolyl]methyl]-3-(2-methylpropyl)-1,1-dioxo-1,2,5-thiadiazepan-4-one::2-[[4-(2,6-dimethylphenyl)phenyl]methyl]-5-[[1-(2-hydroxyethyl)triazol-4-yl]methyl]-3-(2-methylpropyl)-1,1-dioxo-1,2,5-thiadiazepan-4-one::KUC103947::MLS002768202::SMR001788144::cid_45479948 Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113941&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45479948 252663469 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235682 CCCCCCNC(=O)O[C@H]1Cn2n([C@@H]3CN(C[C@]13O)S(=O)(=O)c1ccc(C)cc1)c(=O)n(CCCCCC)c2=O InChI=1S/C28H43N5O7S/c1-4-6-8-10-16-29-25(34)40-24-19-32-26(35)31(17-11-9-7-5-2)27(36)33(32)23-18-30(20-28(23,24)37)41(38,39)22-14-12-21(3)13-15-22/h12-15,23-24,37H,4-11,16-20H2,1-3H3,(H,29,34)/t23-,24+,28-/m1/s1 IRLGTVAJOSFOAX-FMGHJNRGSA-N 113942 MLS002919715::SMR001788784::cid_46902254 Disintegrin and metalloproteinase domain-containing protein 17 69508 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46902254 242053886 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235683 CC(C)C1N(Cc2ccc(cc2)-c2ccccc2)S(=O)(=O)CCN(Cc2cn(CC3CCCCC3)nn2)C1=O InChI=1S/C30H39N5O3S/c1-23(2)29-30(36)33(21-28-22-34(32-31-28)19-24-9-5-3-6-10-24)17-18-39(37,38)35(29)20-25-13-15-27(16-14-25)26-11-7-4-8-12-26/h4,7-8,11-16,22-24,29H,3,5-6,9-10,17-21H2,1-2H3 ATFWUWMCCYSVTG-UHFFFAOYSA-N 113943 5-[[1-(cyclohexylmethyl)-1,2,3-triazol-4-yl]methyl]-1,1-bis(oxidanylidene)-2-[(4-phenylphenyl)methyl]-3-propan-2-yl-1,2,5-thiadiazepan-4-one::5-[[1-(cyclohexylmethyl)-4-triazolyl]methyl]-1,1-dioxo-2-[(4-phenylphenyl)methyl]-3-propan-2-yl-1,2,5-thiadiazepan-4-one::5-[[1-(cyclohexylmethyl)triazol-4-yl]methyl]-1,1-dioxo-2-[(4-phenylphenyl)methyl]-3-propan-2-yl-1,2,5-thiadiazepan-4-one::5-[[1-(cyclohexylmethyl)triazol-4-yl]methyl]-3-isopropyl-1,1-diketo-2-(4-phenylbenzyl)-1,2,5-thiadiazepan-4-one::KUC104736::MLS003116215::SMR001831768::cid_46902974 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113943&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46902974 252663470 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235684 C[C@H](CO)N1C[C@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(Cl)cc2)OCc2ccccc2-c2c(C1=O)n(C)c1ccccc21 InChI=1S/C32H36ClN3O5S/c1-21-17-36(22(2)19-37)32(38)31-30(27-11-7-8-12-28(27)35(31)4)26-10-6-5-9-23(26)20-41-29(21)18-34(3)42(39,40)25-15-13-24(33)14-16-25/h5-16,21-22,29,37H,17-20H2,1-4H3/t21-,22+,29-/m0/s1 VJARKWPJXPJMID-KERYWQKISA-N 83856 MLS003129868::SMR001834314::cid_46903291 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83856 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83856&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46903291 242053779 ZINC72138295 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235685 C[C@H](CO)N1C[C@H](C)[C@@H](CN(C)S(=O)(=O)c2ccc(F)cc2)OCCCC[C@@H](C)Oc2ccc(NC(=O)Nc3ccc(cc3)C(F)(F)F)cc2C1=O InChI=1S/C36H44F4N4O7S/c1-23-20-44(24(2)22-45)34(46)31-19-29(42-35(47)41-28-12-8-26(9-13-28)36(38,39)40)14-17-32(31)51-25(3)7-5-6-18-50-33(23)21-43(4)52(48,49)30-15-10-27(37)11-16-30/h8-17,19,23-25,33,45H,5-7,18,20-22H2,1-4H3,(H2,41,42,47)/t23-,24+,25+,33+/m0/s1 QFGLVRXJBRXPKG-PXHXSQDOSA-N 113944 MLS003128713::SMR001833159::cid_44502712 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113944&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44502712 242053887 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235686 COc1ccc(cc1)S(=O)(=O)N(C)C[C@@H]1OCCCC[C@H](C)Oc2ccc(NC(=O)Nc3ccc(cc3)C(F)(F)F)cc2C(=O)N(C[C@H]1C)[C@H](C)CO InChI=1S/C37H47F3N4O8S/c1-24-21-44(25(2)23-45)35(46)32-20-29(42-36(47)41-28-11-9-27(10-12-28)37(38,39)40)13-18-33(32)52-26(3)8-6-7-19-51-34(24)22-43(4)53(48,49)31-16-14-30(50-5)15-17-31/h9-18,20,24-26,34,45H,6-8,19,21-23H2,1-5H3,(H2,41,42,47)/t24-,25-,26+,34+/m1/s1 NIGUPTAEWCVCOQ-GJWZSCNASA-N 113945 MLS003128829::SMR001833275::cid_46903788 Disintegrin and metalloproteinase domain-containing protein 17 69500 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113945&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46903788 242053888 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235687 CCCCCCn1c(=O)n2C[C@H](OC(=O)NCc3ccc(OC)c(OC)c3)[C@H](OC(=O)NCc3ccc(OC)c(OC)c3)[C@@H](CN(CC#C)S(=O)(=O)c3ccc(C)cc3)n2c1=O InChI=1S/C43H54N6O12S/c1-8-10-11-12-22-47-42(52)48-28-38(60-40(50)44-25-30-15-19-34(56-4)36(23-30)58-6)39(61-41(51)45-26-31-16-20-35(57-5)37(24-31)59-7)33(49(48)43(47)53)27-46(21-9-2)62(54,55)32-17-13-29(3)14-18-32/h2,13-20,23-24,33,38-39H,8,10-12,21-22,25-28H2,1,3-7H3,(H,44,50)(H,45,51)/t33-,38+,39-/m1/s1 CXBODGODPIMIMV-GVFQJMOSSA-N 113946 MLS003107585::N-[(3,4-dimethoxyphenyl)methyl]carbamic acid [(5R,6R,7S)-6-[[(3,4-dimethoxyphenyl)methylamino]-oxomethoxy]-2-hexyl-5-[[(4-methylphenyl)sulfonyl-prop-2-ynylamino]methyl]-1,3-dioxo-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,2-a]pyridazin-7-yl] ester::N-veratrylcarbamic acid [(5R,6R,7S)-2-hexyl-1,3-diketo-5-[[propargyl(tosyl)amino]methyl]-6-(veratrylcarbamoyloxy)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,2-a]pyridazin-7-yl] ester::SMR001822580::[(5R,6R,7S)-6-[(3,4-dimethoxyphenyl)methylcarbamoyloxy]-2-hexyl-5-[[(4-methylphenyl)sulfonyl-prop-2-ynyl-amino]methyl]-1,3-bis(oxidanylidene)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,2-a]pyridazin-7-yl] N-[(3,4-dimethoxyphenyl)methyl]carbamate::[(5R,6R,7S)-6-[(3,4-dimethoxyphenyl)methylcarbamoyloxy]-2-hexyl-5-[[(4-methylphenyl)sulfonyl-prop-2-ynylamino]methyl]-1,3-dioxo-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,2-a]pyridazin-7-yl] N-[(3,4-dimethoxyphenyl)methyl]carbamate::cid_46904297 Disintegrin and metalloproteinase domain-containing protein 17 69509 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113946&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46904297 252663471 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235688 Cc1cc(C)c2c(c1)nc1C(Cc3ccc(O)cc3)NC(=O)c3cc4ccccc4cc3-n1c2=O InChI=1S/C29H23N3O3/c1-16-11-17(2)26-23(12-16)30-27-24(13-18-7-9-21(33)10-8-18)31-28(34)22-14-19-5-3-4-6-20(19)15-25(22)32(27)29(26)35/h3-12,14-15,24,33H,13H2,1-2H3,(H,31,34) YENQUTZFBXRVBM-UHFFFAOYSA-N 113947 MLS003117185::SMR001832682::cid_46904477 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46904477 242053889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235689 CCOC(=O)C1=C(C)N(Cc2ccccc2)C(=O)NC1c1ccccc1OS(=O)(=O)c1ccccc1[N+]([O-])=O InChI=1S/C27H25N3O8S/c1-3-37-26(31)24-18(2)29(17-19-11-5-4-6-12-19)27(32)28-25(24)20-13-7-9-15-22(20)38-39(35,36)23-16-10-8-14-21(23)30(33)34/h4-16,25H,3,17H2,1-2H3,(H,28,32) JKAYRQZBXGXLAV-UHFFFAOYSA-N 113948 3-benzyl-2-keto-4-methyl-6-[2-(2-nitrophenyl)sulfonyloxyphenyl]-1,6-dihydropyrimidine-5-carboxylic acid ethyl ester::4-methyl-6-[2-(2-nitrophenyl)sulfonyloxyphenyl]-2-oxo-3-(phenylmethyl)-1,6-dihydropyrimidine-5-carboxylic acid ethyl ester::MLS003107662::SMR000389007::cid_5461681::ethyl 3-benzyl-4-methyl-6-[2-(2-nitrophenyl)sulfonyloxyphenyl]-2-oxo-1,6-dihydropyrimidine-5-carboxylate::ethyl 4-methyl-6-[2-(2-nitrophenyl)sulfonyloxyphenyl]-2-oxidanylidene-3-(phenylmethyl)-1,6-dihydropyrimidine-5-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69481 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113948&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5461681 252663472 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235690 CC(O)(c1nc(\C=C\c2ccccc2)cs1)c1cccc(F)c1 InChI=1S/C19H16FNOS/c1-19(22,15-8-5-9-16(20)12-15)18-21-17(13-23-18)11-10-14-6-3-2-4-7-14/h2-13,22H,1H3/b11-10+ MWMWVWAYVBIXSC-ZHACJKMWSA-N 113949 1-(3-fluorophenyl)-1-[4-[(E)-2-phenylethenyl]-1,3-thiazol-2-yl]ethanol::1-(3-fluorophenyl)-1-[4-[(E)-2-phenylethenyl]-2-thiazolyl]ethanol::1-(3-fluorophenyl)-1-[4-[(E)-styryl]thiazol-2-yl]ethanol::MLS003122401::SMR001277280::cid_46942445 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113949&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46942445 252663473 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235691 OC(c1nc(cs1)-c1ccc(Cl)cc1)(c1ccccc1)C(F)(F)F InChI=1S/C17H11ClF3NOS/c18-13-8-6-11(7-9-13)14-10-24-15(22-14)16(23,17(19,20)21)12-4-2-1-3-5-12/h1-10,23H XRSSWDIQHUNZKS-UHFFFAOYSA-N 113950 1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-2,2,2-trifluoro-1-phenylethanol::1-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-2,2,2-tris(fluoranyl)-1-phenyl-ethanol::1-[4-(4-chlorophenyl)-2-thiazolyl]-2,2,2-trifluoro-1-phenylethanol::1-[4-(4-chlorophenyl)thiazol-2-yl]-2,2,2-trifluoro-1-phenyl-ethanol::MLS003122508::SMR001277420::cid_46942451 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113950&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46942451 252663474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235692 COc1ccc(OC(F)(F)F)cc1CC1(C)C(=O)Nc2ccc(cc12)-c1ccsc1 InChI=1S/C22H18F3NO3S/c1-21(11-15-9-16(29-22(23,24)25)4-6-19(15)28-2)17-10-13(14-7-8-30-12-14)3-5-18(17)26-20(21)27/h3-10,12H,11H2,1-2H3,(H,26,27) IOBCNVHYRDSUPA-UHFFFAOYSA-N 113951 3-[2-methoxy-5-(trifluoromethoxy)benzyl]-3-methyl-5-(3-thienyl)oxindole::3-[[2-methoxy-5-(trifluoromethoxy)phenyl]methyl]-3-methyl-5-(3-thiophenyl)-1H-indol-2-one::3-[[2-methoxy-5-(trifluoromethoxy)phenyl]methyl]-3-methyl-5-thiophen-3-yl-1H-indol-2-one::3-[[2-methoxy-5-(trifluoromethyloxy)phenyl]methyl]-3-methyl-5-thiophen-3-yl-1H-indol-2-one::MLS003122008::SMR001454011::cid_46942719 Disintegrin and metalloproteinase domain-containing protein 17 69486 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113951&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46942719 252663475 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235693 CC(O)(c1nc(cs1)-c1cccc(c1)C(F)(F)F)c1ccc(F)c(F)c1 InChI=1S/C18H12F5NOS/c1-17(25,11-5-6-13(19)14(20)8-11)16-24-15(9-26-16)10-3-2-4-12(7-10)18(21,22)23/h2-9,25H,1H3 KWQUSCJFUSEKAC-UHFFFAOYSA-N 113952 1-(3,4-difluorophenyl)-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanol::1-(3,4-difluorophenyl)-1-[4-[3-(trifluoromethyl)phenyl]-2-thiazolyl]ethanol::1-(3,4-difluorophenyl)-1-[4-[3-(trifluoromethyl)phenyl]thiazol-2-yl]ethanol::1-[3,4-bis(fluoranyl)phenyl]-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanol::MLS003122754::SMR001277706::cid_46942956 Disintegrin and metalloproteinase domain-containing protein 17 69487 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113952&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46942956 252663476 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235694 CC1(Cc2ccc(o2)C(F)(F)F)C(=O)Nc2cc(ccc12)-c1ccc(F)cc1F InChI=1S/C21H14F5NO2/c1-20(10-13-4-7-18(29-13)21(24,25)26)15-6-2-11(8-17(15)27-19(20)28)14-5-3-12(22)9-16(14)23/h2-9H,10H2,1H3,(H,27,28) HRJAXEODHLKTNZ-UHFFFAOYSA-N 113953 6-(2,4-difluorophenyl)-3-methyl-3-[[5-(trifluoromethyl)-2-furanyl]methyl]-1H-indol-2-one::6-(2,4-difluorophenyl)-3-methyl-3-[[5-(trifluoromethyl)-2-furyl]methyl]oxindole::6-(2,4-difluorophenyl)-3-methyl-3-[[5-(trifluoromethyl)furan-2-yl]methyl]-1H-indol-2-one::6-[2,4-bis(fluoranyl)phenyl]-3-methyl-3-[[5-(trifluoromethyl)furan-2-yl]methyl]-1H-indol-2-one::MLS003121965::SMR001453884::cid_46943756 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113953&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46943756 252663477 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235695 CC1(Cc2ccc(Cl)c(Cl)c2)C(=O)Nc2ccc(cc12)S(=O)(=O)NC1CCCCC1 InChI=1S/C22H24Cl2N2O3S/c1-22(13-14-7-9-18(23)19(24)11-14)17-12-16(8-10-20(17)25-21(22)27)30(28,29)26-15-5-3-2-4-6-15/h7-12,15,26H,2-6,13H2,1H3,(H,25,27) ALDVKAXQFVDGPL-UHFFFAOYSA-N 113954 MLS003121996::N-cyclohexyl-3-(3,4-dichlorobenzyl)-2-keto-3-methyl-indoline-5-sulfonamide::N-cyclohexyl-3-[(3,4-dichlorophenyl)methyl]-3-methyl-2-oxidanylidene-1H-indole-5-sulfonamide::N-cyclohexyl-3-[(3,4-dichlorophenyl)methyl]-3-methyl-2-oxo-1H-indole-5-sulfonamide::SMR001453888::cid_46947932 Disintegrin and metalloproteinase domain-containing protein 17 69495 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113954&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46947932 252663478 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235696 Cc1cc(F)ccc1C(O)c1nc(c[nH]1)-c1cccc(OCc2ccccc2)c1 InChI=1S/C24H21FN2O2/c1-16-12-19(25)10-11-21(16)23(28)24-26-14-22(27-24)18-8-5-9-20(13-18)29-15-17-6-3-2-4-7-17/h2-14,23,28H,15H2,1H3,(H,26,27) GSSVPDVTRMZICO-UHFFFAOYSA-N 113955 (4-fluoranyl-2-methyl-phenyl)-[5-(3-phenylmethoxyphenyl)-1H-imidazol-2-yl]methanol::(4-fluoro-2-methylphenyl)-[5-(3-phenylmethoxyphenyl)-1H-imidazol-2-yl]methanol::MLS003123359::SMR001291243::[5-(3-benzoxyphenyl)-1H-imidazol-2-yl]-(4-fluoro-2-methyl-phenyl)methanol::cid_46948034 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113955&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46948034 252663479 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235697 CCN(Cc1cccc(Br)c1)c1c(CC)nc2ccc(cn12)C(=O)Nc1cccc(OC)c1 InChI=1S/C26H27BrN4O2/c1-4-23-26(30(5-2)16-18-8-6-9-20(27)14-18)31-17-19(12-13-24(31)29-23)25(32)28-21-10-7-11-22(15-21)33-3/h6-15,17H,4-5,16H2,1-3H3,(H,28,32) RVXYWYZDAFWICY-UHFFFAOYSA-N 113956 3-[(3-bromobenzyl)-ethyl-amino]-2-ethyl-N-(3-methoxyphenyl)imidazo[1,2-a]pyridine-6-carboxamide::3-[(3-bromophenyl)methyl-ethyl-amino]-2-ethyl-N-(3-methoxyphenyl)imidazo[1,2-a]pyridine-6-carboxamide::3-[(3-bromophenyl)methyl-ethylamino]-2-ethyl-N-(3-methoxyphenyl)-6-imidazo[1,2-a]pyridinecarboxamide::3-[(3-bromophenyl)methyl-ethylamino]-2-ethyl-N-(3-methoxyphenyl)imidazo[1,2-a]pyridine-6-carboxamide::MLS003121295::SMR001283879::cid_49778214 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49778214 252663480 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235698 OC(c1nc(cs1)-c1cccc(c1)C(F)(F)F)(c1ccccc1)C(F)(F)F InChI=1S/C18H11F6NOS/c19-17(20,21)13-8-4-5-11(9-13)14-10-27-15(25-14)16(26,18(22,23)24)12-6-2-1-3-7-12/h1-10,26H RNURDSFRXIOPHF-UHFFFAOYSA-N 113957 2,2,2-trifluoro-1-phenyl-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanol::2,2,2-trifluoro-1-phenyl-1-[4-[3-(trifluoromethyl)phenyl]-2-thiazolyl]ethanol::2,2,2-trifluoro-1-phenyl-1-[4-[3-(trifluoromethyl)phenyl]thiazol-2-yl]ethanol::2,2,2-tris(fluoranyl)-1-phenyl-1-[4-[3-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]ethanol::MLS003122710::SMR001277661::cid_49778885 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49778885 252663481 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235699 COc1ccc(NC(=O)Cn2nnc(c2COc2ccc3ccccc3c2)-c2ccccc2)cn1 InChI=1S/C27H23N5O3/c1-34-26-14-12-22(16-28-26)29-25(33)17-32-24(27(30-31-32)20-8-3-2-4-9-20)18-35-23-13-11-19-7-5-6-10-21(19)15-23/h2-16H,17-18H2,1H3,(H,29,33) QVPJJIZGBNPDJO-UHFFFAOYSA-N 113958 MLS003121812::N-(6-methoxy-3-pyridinyl)-2-[5-(2-naphthalenyloxymethyl)-4-phenyl-1-triazolyl]acetamide::N-(6-methoxy-3-pyridyl)-2-[5-(2-naphthoxymethyl)-4-phenyl-triazol-1-yl]acetamide::N-(6-methoxypyridin-3-yl)-2-[5-(naphthalen-2-yloxymethyl)-4-phenyl-1,2,3-triazol-1-yl]ethanamide::N-(6-methoxypyridin-3-yl)-2-[5-(naphthalen-2-yloxymethyl)-4-phenyltriazol-1-yl]acetamide::SMR001285249::cid_49786905 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113958&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49786905 252663482 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235700 OC(c1nc(cs1)-c1ccc2OCOc2c1)(c1ccccc1)C(F)(F)F InChI=1S/C18H12F3NO3S/c19-18(20,21)17(23,12-4-2-1-3-5-12)16-22-13(9-26-16)11-6-7-14-15(8-11)25-10-24-14/h1-9,23H,10H2 MOOWXUFMZSHWQQ-UHFFFAOYSA-N 113959 1-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-2,2,2-trifluoro-1-phenylethanol::1-[4-(1,3-benzodioxol-5-yl)-1,3-thiazol-2-yl]-2,2,2-tris(fluoranyl)-1-phenyl-ethanol::1-[4-(1,3-benzodioxol-5-yl)-2-thiazolyl]-2,2,2-trifluoro-1-phenylethanol::1-[4-(1,3-benzodioxol-5-yl)thiazol-2-yl]-2,2,2-trifluoro-1-phenyl-ethanol::MLS003122536::SMR001277448::cid_49789625 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113959&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49789625 252663483 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235701 CC(O)(c1nc(cs1)-c1cc2ccccc2o1)c1ccc(F)c(F)c1 InChI=1S/C19H13F2NO2S/c1-19(23,12-6-7-13(20)14(21)9-12)18-22-15(10-25-18)17-8-11-4-2-3-5-16(11)24-17/h2-10,23H,1H3 DHXJTCOUWHJDHF-UHFFFAOYSA-N 113960 1-[4-(1-benzofuran-2-yl)-1,3-thiazol-2-yl]-1-(3,4-difluorophenyl)ethanol::1-[4-(1-benzofuran-2-yl)-1,3-thiazol-2-yl]-1-[3,4-bis(fluoranyl)phenyl]ethanol::1-[4-(2-benzofuranyl)-2-thiazolyl]-1-(3,4-difluorophenyl)ethanol::1-[4-(benzofuran-2-yl)thiazol-2-yl]-1-(3,4-difluorophenyl)ethanol::MLS003122548::SMR001277464::cid_49790046 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113960&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49790046 252663484 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235702 CCN(Cc1cccc(Br)c1)c1c(CC)nc2ccc(cn12)C(=O)Nc1ccc(OC)c(OC)c1 InChI=1S/C27H29BrN4O3/c1-5-22-27(31(6-2)16-18-8-7-9-20(28)14-18)32-17-19(10-13-25(32)30-22)26(33)29-21-11-12-23(34-3)24(15-21)35-4/h7-15,17H,5-6,16H2,1-4H3,(H,29,33) BZTFYZWQDYGUPP-UHFFFAOYSA-N 113961 3-[(3-bromobenzyl)-ethyl-amino]-N-(3,4-dimethoxyphenyl)-2-ethyl-imidazo[1,2-a]pyridine-6-carboxamide::3-[(3-bromophenyl)methyl-ethyl-amino]-N-(3,4-dimethoxyphenyl)-2-ethyl-imidazo[1,2-a]pyridine-6-carboxamide::3-[(3-bromophenyl)methyl-ethylamino]-N-(3,4-dimethoxyphenyl)-2-ethyl-6-imidazo[1,2-a]pyridinecarboxamide::3-[(3-bromophenyl)methyl-ethylamino]-N-(3,4-dimethoxyphenyl)-2-ethylimidazo[1,2-a]pyridine-6-carboxamide::MLS003121296::SMR001283881::cid_49790693 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49790693 252663485 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235703 COc1cc(ccc1F)C(O)c1nc(cs1)-c1ccc2ccccc2c1 InChI=1S/C21H16FNO2S/c1-25-19-11-16(8-9-17(19)22)20(24)21-23-18(12-26-21)15-7-6-13-4-2-3-5-14(13)10-15/h2-12,20,24H,1H3 UFRIKYPJKXJLKY-UHFFFAOYSA-N 113962 (4-fluoranyl-3-methoxy-phenyl)-(4-naphthalen-2-yl-1,3-thiazol-2-yl)methanol::(4-fluoro-3-methoxy-phenyl)-[4-(2-naphthyl)thiazol-2-yl]methanol::(4-fluoro-3-methoxyphenyl)-(4-naphthalen-2-yl-1,3-thiazol-2-yl)methanol::(4-fluoro-3-methoxyphenyl)-[4-(2-naphthalenyl)-2-thiazolyl]methanol::MLS003122419::SMR001277330::cid_49791454 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113962&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49791454 252663486 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235704 CC1(Cc2cccc(c2)C#N)C(=O)Nc2ccc(cc12)-c1cccc(c1)C(F)(F)F InChI=1S/C24H17F3N2O/c1-23(13-15-4-2-5-16(10-15)14-28)20-12-18(8-9-21(20)29-22(23)30)17-6-3-7-19(11-17)24(25,26)27/h2-12H,13H2,1H3,(H,29,30) LKPSRIPMCUPRPL-UHFFFAOYSA-N 83873 3-[[2-keto-3-methyl-5-[3-(trifluoromethyl)phenyl]indolin-3-yl]methyl]benzonitrile::3-[[3-methyl-2-oxidanylidene-5-[3-(trifluoromethyl)phenyl]-1H-indol-3-yl]methyl]benzenecarbonitrile::3-[[3-methyl-2-oxo-5-[3-(trifluoromethyl)phenyl]-1H-indol-3-yl]methyl]benzonitrile::MLS003121958::SMR001453931::cid_49792284 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=83873 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=83873&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49792284 252659046 ZINC61898755 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235705 CC1(Cc2ccc(o2)C(F)(F)F)C(=O)Nc2ccc(cc12)-c1cccc(c1)C(F)(F)F InChI=1S/C22H15F6NO2/c1-20(11-15-6-8-18(31-15)22(26,27)28)16-10-13(5-7-17(16)29-19(20)30)12-3-2-4-14(9-12)21(23,24)25/h2-10H,11H2,1H3,(H,29,30) FFQUTICDHROJDA-UHFFFAOYSA-N 113963 3-methyl-3-[[5-(trifluoromethyl)-2-furanyl]methyl]-5-[3-(trifluoromethyl)phenyl]-1H-indol-2-one::3-methyl-3-[[5-(trifluoromethyl)-2-furyl]methyl]-5-[3-(trifluoromethyl)phenyl]oxindole::3-methyl-3-[[5-(trifluoromethyl)furan-2-yl]methyl]-5-[3-(trifluoromethyl)phenyl]-1H-indol-2-one::MLS003121967::SMR001453946::cid_49795228 Disintegrin and metalloproteinase domain-containing protein 17 69562 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49795228 252663487 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235706 CC(O)(c1nc(cs1)-c1cc2ccccc2o1)c1ccccc1 InChI=1S/C19H15NO2S/c1-19(21,14-8-3-2-4-9-14)18-20-15(12-23-18)17-11-13-7-5-6-10-16(13)22-17/h2-12,21H,1H3 ZZZMTDBOVOBSDF-UHFFFAOYSA-N 113964 1-[4-(1-benzofuran-2-yl)-1,3-thiazol-2-yl]-1-phenyl-ethanol::1-[4-(1-benzofuran-2-yl)-1,3-thiazol-2-yl]-1-phenylethanol::1-[4-(2-benzofuranyl)-2-thiazolyl]-1-phenylethanol::1-[4-(benzofuran-2-yl)thiazol-2-yl]-1-phenyl-ethanol::MLS003122519::SMR001277427::cid_49795593 Disintegrin and metalloproteinase domain-containing protein 17 69501 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113964&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49795593 252663488 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235707 C[C@H](CO)N1C[C@H](C)[C@H](CN(C)C(=O)Nc2ccc3OCOc3c2)OCCCC[C@@H](C)Oc2ccc(NC(=O)Nc3ccc(cc3)C(F)(F)F)cc2C1=O InChI=1S/C38H46F3N5O8/c1-23-19-46(24(2)21-47)35(48)30-17-28(43-36(49)42-27-10-8-26(9-11-27)38(39,40)41)12-14-31(30)54-25(3)7-5-6-16-51-34(23)20-45(4)37(50)44-29-13-15-32-33(18-29)53-22-52-32/h8-15,17-18,23-25,34,47H,5-7,16,19-22H2,1-4H3,(H,44,50)(H2,42,43,49)/t23-,24+,25+,34-/m0/s1 CVJLGRQJBJPQNN-WEVAMHJFSA-N 113965 MLS003128694::SMR001833140::cid_44617974 Disintegrin and metalloproteinase domain-containing protein 17 69479 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113965&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44617974 242053890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235708 Oc1ccc(C[C@H]2CNC(=S)N2CC2CCCN2C[C@H](Cc2ccccc2)N2C[C@H](Cc3ccc(O)cc3)N(CC3CCCCC3)C2=S)cc1 InChI=1S/C41H53N5O2S2/c47-38-17-13-31(14-18-38)22-35-25-42-40(49)44(35)28-34-12-7-21-43(34)27-36(23-30-8-3-1-4-9-30)46-29-37(24-32-15-19-39(48)20-16-32)45(41(46)50)26-33-10-5-2-6-11-33/h1,3-4,8-9,13-20,33-37,47-48H,2,5-7,10-12,21-29H2,(H,42,49)/t34?,35-,36-,37-/m0/s1 ROVGVQKXMAMTLO-DBKYYFATSA-N 113966 (4S)-1-[(1S)-1-benzyl-2-[2-[[(5S)-5-(4-hydroxybenzyl)-2-thioxo-imidazolidin-1-yl]methyl]pyrrolidino]ethyl]-3-(cyclohexylmethyl)-4-(4-hydroxybenzyl)imidazolidine-2-thione::(4S)-3-(cyclohexylmethyl)-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-[2-[[(5S)-5-[(4-hydroxyphenyl)methyl]-2-sulfanylidene-1-imidazolidinyl]methyl]-1-pyrrolidinyl]-3-phenylpropan-2-yl]-2-imidazolidinethione::(4S)-3-(cyclohexylmethyl)-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-[2-[[(5S)-5-[(4-hydroxyphenyl)methyl]-2-sulfanylidene-imidazolidin-1-yl]methyl]pyrrolidin-1-yl]-3-phenyl-propan-2-yl]imidazolidine-2-thione::(4S)-3-(cyclohexylmethyl)-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-[2-[[(5S)-5-[(4-hydroxyphenyl)methyl]-2-sulfanylideneimidazolidin-1-yl]methyl]pyrrolidin-1-yl]-3-phenylpropan-2-yl]imidazolidine-2-thione::MLS003177381::SMR001881160::cid_51359455 Disintegrin and metalloproteinase domain-containing protein 17 69502 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113966&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51359455 252663489 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235709 CCOc1ccc(CCN2[C@@H](Cc3ccc(O)cc3)CN([C@H](CN3CCC[C@@H]3CN3[C@@H](CC(C)C)CNC3=S)Cc3ccc(O)cc3)C2=S)cc1 InChI=1S/C41H55N5O3S2/c1-4-49-39-17-11-30(12-18-39)19-21-44-36(24-32-9-15-38(48)16-10-32)28-46(41(44)51)35(23-31-7-13-37(47)14-8-31)26-43-20-5-6-33(43)27-45-34(22-29(2)3)25-42-40(45)50/h7-18,29,33-36,47-48H,4-6,19-28H2,1-3H3,(H,42,50)/t33-,34+,35+,36+/m1/s1 ALEFYJITYVGOBP-WISKXVKBSA-N 113967 (4S)-3-[2-(4-ethoxyphenyl)ethyl]-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2R)-2-[[(5S)-5-(2-methylpropyl)-2-sulfanylidene-1-imidazolidinyl]methyl]-1-pyrrolidinyl]propan-2-yl]-2-imidazolidinethione::(4S)-3-[2-(4-ethoxyphenyl)ethyl]-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2R)-2-[[(5S)-5-(2-methylpropyl)-2-sulfanylidene-imidazolidin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]imidazolidine-2-thione::(4S)-3-[2-(4-ethoxyphenyl)ethyl]-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2R)-2-[[(5S)-5-(2-methylpropyl)-2-sulfanylideneimidazolidin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]imidazolidine-2-thione::(4S)-4-(4-hydroxybenzyl)-1-[(1S)-1-(4-hydroxybenzyl)-2-[(2R)-2-[[(5S)-5-isobutyl-2-thioxo-imidazolidin-1-yl]methyl]pyrrolidino]ethyl]-3-(2-p-phenetylethyl)imidazolidine-2-thione::MLS003177399::SMR001881178::cid_51359471 Disintegrin and metalloproteinase domain-containing protein 17 69473 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113967&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51359471 252663490 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235710 CCOc1ccc(CCN2[C@@H](Cc3ccccc3)CN([C@H](CN3CCC[C@@H]3CN3[C@@H](CC(C)C)CNC3=S)Cc3ccc(O)cc3)C2=S)cc1 InChI=1S/C41H55N5O2S2/c1-4-48-39-18-14-31(15-19-39)20-22-44-37(24-32-9-6-5-7-10-32)29-46(41(44)50)36(25-33-12-16-38(47)17-13-33)27-43-21-8-11-34(43)28-45-35(23-30(2)3)26-42-40(45)49/h5-7,9-10,12-19,30,34-37,47H,4,8,11,20-29H2,1-3H3,(H,42,49)/t34-,35+,36+,37+/m1/s1 SVKHAVGWIITPOK-HQPLKVBUSA-N 113968 (4S)-3-[2-(4-ethoxyphenyl)ethyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2R)-2-[[(5S)-5-(2-methylpropyl)-2-sulfanylidene-1-imidazolidinyl]methyl]-1-pyrrolidinyl]propan-2-yl]-4-(phenylmethyl)-2-imidazolidinethione::(4S)-3-[2-(4-ethoxyphenyl)ethyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2R)-2-[[(5S)-5-(2-methylpropyl)-2-sulfanylidene-imidazolidin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(phenylmethyl)imidazolidine-2-thione::(4S)-4-benzyl-1-[(1S)-1-(4-hydroxybenzyl)-2-[(2R)-2-[[(5S)-5-isobutyl-2-thioxo-imidazolidin-1-yl]methyl]pyrrolidino]ethyl]-3-(2-p-phenetylethyl)imidazolidine-2-thione::(4S)-4-benzyl-3-[2-(4-ethoxyphenyl)ethyl]-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2R)-2-[[(5S)-5-(2-methylpropyl)-2-sulfanylideneimidazolidin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]imidazolidine-2-thione::MLS003177408::SMR001881187::cid_51359479 Disintegrin and metalloproteinase domain-containing protein 17 69534 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113968&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51359479 252663491 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235711 Oc1ccc(C[C@H]2CNC(=S)N2C[C@H]2CCCN2C[C@H](Cc2ccccc2)N2C[C@H](Cc3ccc(O)cc3)N(CCc3ccccc3)C2=S)cc1 InChI=1S/C42H49N5O2S2/c48-39-17-13-33(14-18-39)24-36-27-43-41(50)46(36)29-35-12-7-22-44(35)28-37(25-32-10-5-2-6-11-32)47-30-38(26-34-15-19-40(49)20-16-34)45(42(47)51)23-21-31-8-3-1-4-9-31/h1-6,8-11,13-20,35-38,48-49H,7,12,21-30H2,(H,43,50)/t35-,36+,37+,38+/m1/s1 HJLIQEBRJUVETG-SPWOZAQASA-N 113969 (4S)-1-[(1S)-1-benzyl-2-[(2R)-2-[[(5S)-5-(4-hydroxybenzyl)-2-thioxo-imidazolidin-1-yl]methyl]pyrrolidino]ethyl]-4-(4-hydroxybenzyl)-3-phenethyl-imidazolidine-2-thione::(4S)-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-[(2R)-2-[[(5S)-5-[(4-hydroxyphenyl)methyl]-2-sulfanylidene-1-imidazolidinyl]methyl]-1-pyrrolidinyl]-3-phenylpropan-2-yl]-3-(2-phenylethyl)-2-imidazolidinethione::(4S)-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-[(2R)-2-[[(5S)-5-[(4-hydroxyphenyl)methyl]-2-sulfanylidene-imidazolidin-1-yl]methyl]pyrrolidin-1-yl]-3-phenyl-propan-2-yl]-3-(2-phenylethyl)imidazolidine-2-thione::(4S)-4-[(4-hydroxyphenyl)methyl]-1-[(2S)-1-[(2R)-2-[[(5S)-5-[(4-hydroxyphenyl)methyl]-2-sulfanylideneimidazolidin-1-yl]methyl]pyrrolidin-1-yl]-3-phenylpropan-2-yl]-3-(2-phenylethyl)imidazolidine-2-thione::MLS003177417::SMR001881196::cid_51359484 Disintegrin and metalloproteinase domain-containing protein 17 69489 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113969&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51359484 252663492 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235712 FC(F)(F)Oc1ccccc1C(N1CCC(CC1)n1c2ccccc2[nH]c1=O)c1nnnn1-c1ccc2OCCOc2c1 InChI=1S/C29H26F3N7O4/c30-29(31,32)43-23-8-4-1-5-20(23)26(27-34-35-36-39(27)19-9-10-24-25(17-19)42-16-15-41-24)37-13-11-18(12-14-37)38-22-7-3-2-6-21(22)33-28(38)40/h1-10,17-18,26H,11-16H2,(H,33,40) HODOTLLHIOAMTF-UHFFFAOYSA-N 113970 3-[1-[[1-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2,3,4-tetrazol-5-yl]-[2-(trifluoromethyloxy)phenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one::3-[1-[[1-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-tetrazolyl]-[2-(trifluoromethoxy)phenyl]methyl]-4-piperidinyl]-1H-benzimidazol-2-one::3-[1-[[1-(2,3-dihydro-1,4-benzodioxin-6-yl)tetrazol-5-yl]-[2-(trifluoromethoxy)phenyl]methyl]-4-piperidyl]-1H-benzimidazol-2-one::3-[1-[[1-(2,3-dihydro-1,4-benzodioxin-6-yl)tetrazol-5-yl]-[2-(trifluoromethoxy)phenyl]methyl]piperidin-4-yl]-1H-benzimidazol-2-one::MLS003315657::SMR001994792::cid_51360317 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113970&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51360317 252663493 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235713 O=C1NCN(c2ccccc2)C11CCN(CC1)C(c1nnnn1Cc1ccccc1)c1cccc2ccccc12 InChI=1S/C32H31N7O/c40-31-32(38(23-33-31)26-14-5-2-6-15-26)18-20-37(21-19-32)29(28-17-9-13-25-12-7-8-16-27(25)28)30-34-35-36-39(30)22-24-10-3-1-4-11-24/h1-17,29H,18-23H2,(H,33,40) UKPDNXJADJQOLZ-UHFFFAOYSA-N 113971 8-[(1-benzyltetrazol-5-yl)-(1-naphthyl)methyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[(1-benzyltetrazol-5-yl)-naphthalen-1-ylmethyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[1-naphthalenyl-[1-(phenylmethyl)-5-tetrazolyl]methyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::8-[naphthalen-1-yl-[1-(phenylmethyl)-1,2,3,4-tetrazol-5-yl]methyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one::MLS003265710::SMR001941253::cid_51360815 Disintegrin and metalloproteinase domain-containing protein 17 69548 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51360815 252663494 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235714 O=C(Nc1ccc2OCCOc2c1)C(N1CCC(Cc2ccccc2)CC1)c1ccnc2ccccc12 InChI=1S/C31H31N3O3/c35-31(33-24-10-11-28-29(21-24)37-19-18-36-28)30(26-12-15-32-27-9-5-4-8-25(26)27)34-16-13-23(14-17-34)20-22-6-2-1-3-7-22/h1-12,15,21,23,30H,13-14,16-20H2,(H,33,35) BKMVNVABKQMQQW-UHFFFAOYSA-N 113972 2-(4-benzylpiperidin-1-yl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-quinolin-4-ylacetamide::2-(4-benzylpiperidino)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-(4-quinolyl)acetamide::MLS003355832::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(phenylmethyl)-1-piperidinyl]-2-(4-quinolinyl)acetamide::N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[4-(phenylmethyl)piperidin-1-yl]-2-quinolin-4-yl-ethanamide::SMR002044397::cid_51361391 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51361391 252663495 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235715 CCCCC[C@@H](C)N1C[C@@H](COCc2ccccc2)Oc2cc(ccc2S1(=O)=O)N1CC[C@H](O)C1 InChI=1S/C27H38N2O5S/c1-3-4-6-9-21(2)29-18-25(20-33-19-22-10-7-5-8-11-22)34-26-16-23(28-15-14-24(30)17-28)12-13-27(26)35(29,31)32/h5,7-8,10-13,16,21,24-25,30H,3-4,6,9,14-15,17-20H2,1-2H3/t21-,24+,25+/m1/s1 JWQCWWBNCKQWMW-ZODMCCGTSA-N 113973 (3S)-1-[(4S)-2-[(2R)-heptan-2-yl]-1,1-bis(oxidanylidene)-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::(3S)-1-[(4S)-2-[(2R)-heptan-2-yl]-1,1-dioxo-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]-3-pyrrolidinol::(3S)-1-[(4S)-2-[(2R)-heptan-2-yl]-1,1-dioxo-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::(3S)-1-[(4S)-4-(benzoxymethyl)-1,1-diketo-2-[(1R)-1-methylhexyl]-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::MLS003591780::SMR002253076::cid_53301544 Disintegrin and metalloproteinase domain-containing protein 17 69510 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113973&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53301544 252663496 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235716 CCCCC[C@H](C)N1C[C@@H](COCc2ccccc2)Oc2cc(ccc2S1(=O)=O)N1CC[C@H](O)C1 InChI=1S/C27H38N2O5S/c1-3-4-6-9-21(2)29-18-25(20-33-19-22-10-7-5-8-11-22)34-26-16-23(28-15-14-24(30)17-28)12-13-27(26)35(29,31)32/h5,7-8,10-13,16,21,24-25,30H,3-4,6,9,14-15,17-20H2,1-2H3/t21-,24-,25-/m0/s1 JWQCWWBNCKQWMW-TUSQITKMSA-N 113974 (3S)-1-[(4S)-2-[(2S)-heptan-2-yl]-1,1-bis(oxidanylidene)-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::(3S)-1-[(4S)-2-[(2S)-heptan-2-yl]-1,1-dioxo-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]-3-pyrrolidinol::(3S)-1-[(4S)-2-[(2S)-heptan-2-yl]-1,1-dioxo-4-(phenylmethoxymethyl)-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::(3S)-1-[(4S)-4-(benzoxymethyl)-1,1-diketo-2-[(1S)-1-methylhexyl]-3,4-dihydro-5,,2-benzoxathiazepin-7-yl]pyrrolidin-3-ol::MLS003591782::SMR002253078::cid_53301546 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113974&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53301546 252663497 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235717 Nc1[nH]c(C(=O)c2ccccc2)c(c1C(=O)NCCc1c[nH]c2ccccc12)-c1cccc(c1)C(F)(F)F InChI=1S/C29H23F3N4O2/c30-29(31,32)20-10-6-9-18(15-20)23-24(27(33)36-25(23)26(37)17-7-2-1-3-8-17)28(38)34-14-13-19-16-35-22-12-5-4-11-21(19)22/h1-12,15-16,35-36H,13-14,33H2,(H,34,38) CXHJLXMDNOSDLX-UHFFFAOYSA-N 113975 2-amino-5-benzoyl-N-[2-(1H-indol-3-yl)ethyl]-4-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide::2-azanyl-N-[2-(1H-indol-3-yl)ethyl]-5-(phenylcarbonyl)-4-[3-(trifluoromethyl)phenyl]-1H-pyrrole-3-carboxamide::MLS003826388::N-(2-(1H-indol-3-yl)ethyl)-2-amino-5-benzoyl-4-(3-(trifluoromethyl)phenyl)-1H-pyrrole-3-carboxamide::SMR002504575::cid_56588246 Disintegrin and metalloproteinase domain-containing protein 17 69562 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56588246 252663498 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235718 CC(C)(C)c1ccc(cc1)-c1nnc(SCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)n1-c1ccc(Cl)cc1 InChI=1S/C29H27ClN6O3S3/c1-29(2,3)20-6-4-19(5-7-20)26-33-34-28(36(26)23-12-8-21(30)9-13-23)41-18-25(37)32-22-10-14-24(15-11-22)42(38,39)35-27-31-16-17-40-27/h4-17H,18H2,1-3H3,(H,31,35)(H,32,37) VOWQLQBNOUOWQS-UHFFFAOYSA-N 113976 2-[[5-(4-tert-butylphenyl)-4-(4-chlorophenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide::2-[[5-(4-tert-butylphenyl)-4-(4-chlorophenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide::2-[[5-(4-tert-butylphenyl)-4-(4-chlorophenyl)-1,2,4-triazol-3-yl]thio]-N-[4-(2-thiazolylsulfamoyl)phenyl]acetamide::2-[[5-(4-tert-butylphenyl)-4-(4-chlorophenyl)-1,2,4-triazol-3-yl]thio]-N-[4-(thiazol-2-ylsulfamoyl)phenyl]acetamide::MLS003127770::SMR001835833::cid_24210102 Disintegrin and metalloproteinase domain-containing protein 17 69493 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113976&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24210102 252663499 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235719 CCOc1ccc(cc1)-n1c(SCC(=O)Nc2ccc(cc2)S(=O)(=O)Nc2nccs2)nnc1-c1ccc(cc1)C(C)(C)C InChI=1S/C31H32N6O4S3/c1-5-41-25-14-12-24(13-15-25)37-28(21-6-8-22(9-7-21)31(2,3)4)34-35-30(37)43-20-27(38)33-23-10-16-26(17-11-23)44(39,40)36-29-32-18-19-42-29/h6-19H,5,20H2,1-4H3,(H,32,36)(H,33,38) ZSHRKDDXJFWEOD-UHFFFAOYSA-N 113977 2-[[5-(4-tert-butylphenyl)-4-(4-ethoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]acetamide::2-[[5-(4-tert-butylphenyl)-4-(4-ethoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]ethanamide::2-[[5-(4-tert-butylphenyl)-4-(4-ethoxyphenyl)-1,2,4-triazol-3-yl]thio]-N-[4-(2-thiazolylsulfamoyl)phenyl]acetamide::2-[[5-(4-tert-butylphenyl)-4-p-phenetyl-1,2,4-triazol-3-yl]thio]-N-[4-(thiazol-2-ylsulfamoyl)phenyl]acetamide::MLS003127777::SMR001835840::cid_24210117 Disintegrin and metalloproteinase domain-containing protein 17 69496 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113977&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24210117 252663500 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235720 COc1cc(NC(=O)c2ccccc2)c(C)cc1NC(=O)CSc1nnc(-c2ccccc2F)n1-c1ccc(C)cc1 InChI=1S/C32H28FN5O3S/c1-20-13-15-23(16-14-20)38-30(24-11-7-8-12-25(24)33)36-37-32(38)42-19-29(39)34-27-17-21(2)26(18-28(27)41-3)35-31(40)22-9-5-4-6-10-22/h4-18H,19H2,1-3H3,(H,34,39)(H,35,40) XMHAVDSFLHKWTL-UHFFFAOYSA-N 113978 MLS003127874::N-[4-[2-[[5-(2-fluorophenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanoylamino]-5-methoxy-2-methyl-phenyl]benzamide::N-[4-[[2-[[5-(2-fluorophenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetyl]amino]-5-methoxy-2-methylphenyl]benzamide::N-[4-[[2-[[5-(2-fluorophenyl)-4-(4-methylphenyl)-1,2,4-triazol-3-yl]thio]-1-oxoethyl]amino]-5-methoxy-2-methylphenyl]benzamide::N-[4-[[2-[[5-(2-fluorophenyl)-4-(p-tolyl)-1,2,4-triazol-3-yl]thio]acetyl]amino]-5-methoxy-2-methyl-phenyl]benzamide::SMR001835936::cid_24210351 Disintegrin and metalloproteinase domain-containing protein 17 69541 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113978&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24210351 252663501 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235721 Cc1ccc(cc1)-n1c(Cc2cccs2)nnc1SCC(=O)Nc1ccc(OCc2ccccc2)cc1 InChI=1S/C29H26N4O2S2/c1-21-9-13-24(14-10-21)33-27(18-26-8-5-17-36-26)31-32-29(33)37-20-28(34)30-23-11-15-25(16-12-23)35-19-22-6-3-2-4-7-22/h2-17H,18-20H2,1H3,(H,30,34) WQJJTMKNICSPIM-UHFFFAOYSA-N 113979 2-[[4-(4-methylphenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenylmethoxyphenyl)acetamide::2-[[4-(4-methylphenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenylmethoxyphenyl)ethanamide::2-[[4-(4-methylphenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]-N-(4-phenylmethoxyphenyl)acetamide::MLS003128018::N-(4-benzoxyphenyl)-2-[[4-(p-tolyl)-5-(2-thenyl)-1,2,4-triazol-3-yl]thio]acetamide::SMR001836080::cid_1833867 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113979&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1833867 252663502 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235722 Clc1ccc(cc1)-n1c(Cc2cccs2)nnc1SCC(=O)Nc1ccc(OCc2ccccc2)cc1 InChI=1S/C28H23ClN4O2S2/c29-21-8-12-23(13-9-21)33-26(17-25-7-4-16-36-25)31-32-28(33)37-19-27(34)30-22-10-14-24(15-11-22)35-18-20-5-2-1-3-6-20/h1-16H,17-19H2,(H,30,34) JGWUORYRXHLDJV-UHFFFAOYSA-N 113980 2-[[4-(4-chlorophenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenylmethoxyphenyl)acetamide::2-[[4-(4-chlorophenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenylmethoxyphenyl)ethanamide::2-[[4-(4-chlorophenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]-N-(4-phenylmethoxyphenyl)acetamide::MLS003128026::N-(4-benzoxyphenyl)-2-[[4-(4-chlorophenyl)-5-(2-thenyl)-1,2,4-triazol-3-yl]thio]acetamide::SMR001836088::cid_1836869 Disintegrin and metalloproteinase domain-containing protein 17 69497 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113980&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1836869 252663503 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235723 COc1ccc(cc1)-n1c(Cc2cccs2)nnc1SCC(=O)Nc1ccc(OCc2ccccc2)cc1 InChI=1S/C29H26N4O3S2/c1-35-24-15-11-23(12-16-24)33-27(18-26-8-5-17-37-26)31-32-29(33)38-20-28(34)30-22-9-13-25(14-10-22)36-19-21-6-3-2-4-7-21/h2-17H,18-20H2,1H3,(H,30,34) WHZRGLCOYNCFFZ-UHFFFAOYSA-N 113981 2-[[4-(4-methoxyphenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenylmethoxyphenyl)acetamide::2-[[4-(4-methoxyphenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenylmethoxyphenyl)ethanamide::2-[[4-(4-methoxyphenyl)-5-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]thio]-N-(4-phenylmethoxyphenyl)acetamide::MLS003128027::N-(4-benzoxyphenyl)-2-[[4-(4-methoxyphenyl)-5-(2-thenyl)-1,2,4-triazol-3-yl]thio]acetamide::SMR001836089::cid_1872111 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113981&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1872111 252663504 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235724 CCN(CC)c1ccc(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccc(C)cc2)cc1 InChI=1S/C27H28N4O2S/c1-4-30(5-2)21-16-12-20(13-17-21)28-25(32)18-34-27-29-24-9-7-6-8-23(24)26(33)31(27)22-14-10-19(3)11-15-22/h6-17H,4-5,18H2,1-3H3,(H,28,32) TUMSWNFXCBTFCZ-UHFFFAOYSA-N 113982 MLS003128057::N-[4-(diethylamino)phenyl]-2-[3-(4-methylphenyl)-4-oxidanylidene-quinazolin-2-yl]sulfanyl-ethanamide::N-[4-(diethylamino)phenyl]-2-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]sulfanylacetamide::N-[4-(diethylamino)phenyl]-2-[[3-(4-methylphenyl)-4-oxo-2-quinazolinyl]thio]acetamide::N-[4-(diethylamino)phenyl]-2-[[4-keto-3-(p-tolyl)quinazolin-2-yl]thio]acetamide::SMR001836117::cid_1990867 Disintegrin and metalloproteinase domain-containing protein 17 69504 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113982&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1990867 252663505 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235725 CC(=NNC(=O)CSc1nnc(-c2ccc(cc2)C(C)(C)C)n1-c1ccccc1)c1cccc2ccccc12 InChI=1S/C32H31N5OS/c1-22(27-16-10-12-23-11-8-9-15-28(23)27)33-34-29(38)21-39-31-36-35-30(37(31)26-13-6-5-7-14-26)24-17-19-25(20-18-24)32(2,3)4/h5-20H,21H2,1-4H3,(H,34,38) GXYKUBCLNXLDAO-UHFFFAOYSA-N 113983 2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-(1-naphthalen-1-ylethylideneamino)acetamide::2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]sulfanyl]-N-(1-naphthalen-1-ylethylideneamino)ethanamide::2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]thio]-N-[1-(1-naphthalenyl)ethylideneamino]acetamide::2-[[5-(4-tert-butylphenyl)-4-phenyl-1,2,4-triazol-3-yl]thio]-N-[1-(1-naphthyl)ethylideneamino]acetamide::MLS003128325::SMR001836369::cid_4366183 Disintegrin and metalloproteinase domain-containing protein 17 69513 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113983&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9659437 252663506 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235726 O=C(CSc1nnc(-c2cccs2)n1Cc1ccco1)Nc1ccc(Oc2ccccc2)cc1 InChI=1S/C25H20N4O3S2/c30-23(26-18-10-12-20(13-11-18)32-19-6-2-1-3-7-19)17-34-25-28-27-24(22-9-5-15-33-22)29(25)16-21-8-4-14-31-21/h1-15H,16-17H2,(H,26,30) OXMSNJXHWGQZEN-UHFFFAOYSA-N 113984 2-[[4-(2-furanylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]thio]-N-(4-phenoxyphenyl)acetamide::2-[[4-(2-furfuryl)-5-(2-thienyl)-1,2,4-triazol-3-yl]thio]-N-(4-phenoxyphenyl)acetamide::2-[[4-(furan-2-ylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenoxyphenyl)acetamide::2-[[4-(furan-2-ylmethyl)-5-thiophen-2-yl-1,2,4-triazol-3-yl]sulfanyl]-N-(4-phenoxyphenyl)ethanamide::MLS003127624::SMR001835688::cid_1890903 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113984&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 1890903 252663507 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235727 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 25.41 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235728 C[C@@H](COC(=O)C(C)(C)C)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc(F)cc2)OCCCC[C@H](C)Oc2ccc(NC(=O)Nc3ccccc3)cc2C1=O InChI=1S/C40H53FN4O8S/c1-27-24-45(28(2)26-52-38(47)40(4,5)6)37(46)34-23-32(43-39(48)42-31-14-9-8-10-15-31)18-21-35(34)53-29(3)13-11-12-22-51-36(27)25-44(7)54(49,50)33-19-16-30(41)17-20-33/h8-10,14-21,23,27-29,36H,11-13,22,24-26H2,1-7H3,(H2,42,43,48)/t27-,28+,29+,36+/m1/s1 JYLJYHDOXFQHEK-WVEXKQSWSA-N 113985 CAM-9-026::MLS003448150::SMR002121665::cid_49849931 Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113985&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849931 242053891 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235729 CCCCCCCCNS(=O)(=O)C=Cc1ccccc1CNC(=O)OC(C)(C)C InChI=1S/C22H36N2O4S/c1-5-6-7-8-9-12-16-24-29(26,27)17-15-19-13-10-11-14-20(19)18-23-21(25)28-22(2,3)4/h10-11,13-15,17,24H,5-9,12,16,18H2,1-4H3,(H,23,25) IQUHJGYUHTUBPQ-UHFFFAOYSA-N 113986 MLS003875557::N-[2-[(E)-2-(octylsulfamoyl)vinyl]benzyl]carbamic acid tert-butyl ester::N-[[2-[(E)-2-(octylsulfamoyl)ethenyl]phenyl]methyl]carbamic acid tert-butyl ester::SMR002532570::cid_60156754::tert-butyl N-[[2-[(E)-2-(octylsulfamoyl)ethenyl]phenyl]methyl]carbamate Disintegrin and metalloproteinase domain-containing protein 17 69597 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113986&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60156754 252663508 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235730 CCCCCCCCN1C(=O)[C@@H](CC(=O)NCc2ccc(OC)c(OC)c2)C[C@@]2([C@H](O[C@H](C=C12)C(C)C)C1CC1)C(=O)OC InChI=1S/C35H52N2O7/c1-7-8-9-10-11-12-17-37-30-20-28(23(2)3)44-32(25-14-15-25)35(30,34(40)43-6)21-26(33(37)39)19-31(38)36-22-24-13-16-27(41-4)29(18-24)42-5/h13,16,18,20,23,25-26,28,32H,7-12,14-15,17,19,21-22H2,1-6H3,(H,36,38)/t26-,28+,32+,35+/m0/s1 HMUQJRZTGCHCFQ-ZTDRBNPFSA-N 113987 (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxoethyl]-1-octyl-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::(3R,4aR,5R,7S)-5-cyclopropyl-7-isopropyl-2-keto-3-[2-keto-2-(veratrylamino)ethyl]-1-octyl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::MLS003874263::SMR002530928::cid_60156984::methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxidanylidene-ethyl]-1-octyl-2-oxidanylidene-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate::methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-[(3,4-dimethoxyphenyl)methylamino]-2-oxoethyl]-1-octyl-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69527 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113987&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60156984 252663509 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235731 COC(=O)[C@]12C[C@H](CC(=O)NCCC(C)C)C(=O)N(Cc3cccc4ccccc34)C1=C[C@@H](O[C@@H]2C1CC1)C(C)C InChI=1S/C34H44N2O5/c1-21(2)15-16-35-30(37)17-26-19-34(33(39)40-5)29(18-28(22(3)4)41-31(34)24-13-14-24)36(32(26)38)20-25-11-8-10-23-9-6-7-12-27(23)25/h6-12,18,21-22,24,26,28,31H,13-17,19-20H2,1-5H3,(H,35,37)/t26-,28+,31+,34+/m0/s1 HEDYJXFGEFCOFQ-WDQYGXBDSA-N 113988 (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(3-methylbutylamino)-2-oxoethyl]-1-(1-naphthalenylmethyl)-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::(3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(isoamylamino)-2-keto-ethyl]-7-isopropyl-2-keto-1-(1-naphthylmethyl)-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylic acid methyl ester::MLS003876098::SMR002533043::cid_60157266::methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(3-methylbutylamino)-2-oxidanylidene-ethyl]-1-(naphthalen-1-ylmethyl)-2-oxidanylidene-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate::methyl (3R,4aR,5R,7S)-5-cyclopropyl-3-[2-(3-methylbutylamino)-2-oxoethyl]-1-(naphthalen-1-ylmethyl)-2-oxo-7-propan-2-yl-3,4,5,7-tetrahydropyrano[4,3-b]pyridine-4a-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 69488 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113988&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60157266 252663510 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235732 CN1[C@H]2CC[C@H](CC(=O)NCC(F)(F)F)O[C@@H]2COc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2C1=O InChI=1S/C24H25F4N3O6S/c1-31-19-8-5-16(11-22(32)29-13-24(26,27)28)37-21(19)12-36-20-9-4-15(10-18(20)23(31)33)30-38(34,35)17-6-2-14(25)3-7-17/h2-4,6-7,9-10,16,19,21,30H,5,8,11-13H2,1H3,(H,29,32)/t16-,19+,21-/m1/s1 FVXBGMBMLZPPSG-LKUPVBHCSA-N 113989 2-[(2R,4aS,12aS)-8-[(4-fluorophenyl)sulfonylamino]-5-methyl-6-oxidanylidene-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-[2,2,2-tris(fluoranyl)ethyl]ethanamide::2-[(2R,4aS,12aS)-8-[(4-fluorophenyl)sulfonylamino]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::2-[(2R,4aS,12aS)-8-[(4-fluorophenyl)sulfonylamino]-6-keto-5-methyl-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(2,2,2-trifluoroethyl)acetamide::MLS004342426::SMR003100801::cid_60159039 Disintegrin and metalloproteinase domain-containing protein 17 69562 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113989&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 60159039 252663511 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 235733 CN1[C@H]2CC[C@H](CC(=O)NCc3ccc(cc3)-c3ccccc3)O[C@@H]2COc2ccc(NC(=O)Nc3ccccc3F)cc2C1=O InChI=1S/C36H35FN4O5/c1-41-31-17-16-27(20-34(42)38-21-23-11-13-25(14-12-23)24-7-3-2-4-8-24)46-33(31)22-45-32-18-15-26(19-28(32)35(41)43)39-36(44)40-30-10-6-5-9-29(30)37/h2-15,18-19,27,31,33H,16-17,20-22H2,1H3,(H,38,42)(H2,39,40,44)/t27-,31+,33-/m1/s1 CNKJVVMJWSTYMR-QMOBXOPCSA-N 113990 2-[(2R,4aS,12aS)-8-[(2-fluorophenyl)carbamoylamino]-5-methyl-6-oxidanylidene-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-[(4-phenylphenyl)methyl]ethanamide::2-[(2R,4aS,12aS)-8-[(2-fluorophenyl)carbamoylamino]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-[(4-phenylphenyl)methyl]acetamide::2-[(2R,4aS,12aS)-8-[(2-fluorophenyl)carbamoylamino]-6-keto-5-methyl-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-(4-phenylbenzyl)acetamide::2-[(2R,4aS,12aS)-8-[[(2-fluoroanilino)-oxomethyl]amino]-5-methyl-6-oxo-2,3,4,4a,12,12a-hexahydropyrano[2,3-c][1,5]benzoxazocin-2-yl]-N-[(4-phenylphenyl)methyl]acetamide::MLS004342537::SMR003100912::cid_54654643 Disintegrin and metalloproteinase domain-containing protein 17 69520 PubChem 10.7270/Q2DV1HJQ aid743253 PubChem, PC The Scripps Research Institute Molecular Screening Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113990&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54654643 252663512 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320786 CC#CCOc1ccc(cc1)C(=O)NCC(N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C19H26N4O6S/c1-3-4-13-29-16-7-5-15(6-8-16)18(24)20-14-17(19(25)21-26)22-9-11-23(12-10-22)30(2,27)28/h5-8,17,26H,9-14H2,1-2H3,(H,20,24)(H,21,25) GHBQSNPRMVUGFE-UHFFFAOYSA-N 175075 US9115102, Ex1 Disintegrin and metalloproteinase domain-containing protein 17 32 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175075 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175075&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029814 313043881 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320787 CC#CCOc1ccc(cc1)C(=O)NC[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C19H26N4O6S/c1-3-4-13-29-16-7-5-15(6-8-16)18(24)20-14-17(19(25)21-26)22-9-11-23(12-10-22)30(2,27)28/h5-8,17,26H,9-14H2,1-2H3,(H,20,24)(H,21,25)/t17-/m0/s1 GHBQSNPRMVUGFE-KRWDZBQOSA-N 175076 US9115102, Ex2 Disintegrin and metalloproteinase domain-containing protein 17 28 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175076&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029815 313043882 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320788 COc1ccc(cc1)C(=O)NC[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C16H24N4O6S/c1-26-13-5-3-12(4-6-13)15(21)17-11-14(16(22)18-23)19-7-9-20(10-8-19)27(2,24)25/h3-6,14,23H,7-11H2,1-2H3,(H,17,21)(H,18,22)/t14-/m0/s1 FDYRNGANSUJQHW-AWEZNQCLSA-N 175077 US9115102, Ex4 Disintegrin and metalloproteinase domain-containing protein 17 160 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175077 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175077&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029904 313043883 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320789 CS(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCC2CC2)cc1)C(=O)NO InChI=1S/C19H28N4O6S/c1-30(27,28)23-10-8-22(9-11-23)17(19(25)21-26)12-20-18(24)15-4-6-16(7-5-15)29-13-14-2-3-14/h4-7,14,17,26H,2-3,8-13H2,1H3,(H,20,24)(H,21,25)/t17-/m0/s1 QOLUMVHWHHHJIU-KRWDZBQOSA-N 175078 US9115102, Ex5 Disintegrin and metalloproteinase domain-containing protein 17 200 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175078&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029906 313043884 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320790 CS(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCc2ccccc2)cc1)C(=O)NO InChI=1S/C22H28N4O6S/c1-33(30,31)26-13-11-25(12-14-26)20(22(28)24-29)15-23-21(27)18-7-9-19(10-8-18)32-16-17-5-3-2-4-6-17/h2-10,20,29H,11-16H2,1H3,(H,23,27)(H,24,28)/t20-/m0/s1 FROQCAFCTVROHS-FQEVSTJZSA-N 175079 US9115102, Ex6 Disintegrin and metalloproteinase domain-containing protein 17 40 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175079 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175079&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029905 313043885 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320791 CC#CCOc1ccc(cc1)C(=O)NC[C@H](N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1)C(=O)NO InChI=1S/C25H30N4O6S/c1-3-4-17-35-21-9-7-20(8-10-21)24(30)26-18-23(25(31)27-32)28-13-15-29(16-14-28)36(33,34)22-11-5-19(2)6-12-22/h5-12,23,32H,13-18H2,1-2H3,(H,26,30)(H,27,31)/t23-/m0/s1 QSAWJJFGYRTESR-QHCPKHFHSA-N 175080 US9115102, Ex8 Disintegrin and metalloproteinase domain-containing protein 17 54 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175080&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029908 313043886 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320792 CS(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCc2ccc(F)cc2)cc1)C(=O)NO InChI=1S/C22H27FN4O6S/c1-34(31,32)27-12-10-26(11-13-27)20(22(29)25-30)14-24-21(28)17-4-8-19(9-5-17)33-15-16-2-6-18(23)7-3-16/h2-9,20,30H,10-15H2,1H3,(H,24,28)(H,25,29)/t20-/m0/s1 KMXPLFJAFPNMKW-FQEVSTJZSA-N 175081 US9115102, Ex9 Disintegrin and metalloproteinase domain-containing protein 17 21 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175081 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175081&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 50990957 313043887 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320793 CC#CCOc1ccc(cc1)C(=O)N(C)C[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C20H28N4O6S/c1-4-5-14-30-17-8-6-16(7-9-17)20(26)22(2)15-18(19(25)21-27)23-10-12-24(13-11-23)31(3,28)29/h6-9,18,27H,10-15H2,1-3H3,(H,21,25)/t18-/m0/s1 TWVQSQTXTASYQL-SFHVURJKSA-N 175082 US9115102, Ex13 Disintegrin and metalloproteinase domain-containing protein 17 22 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175082 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175082&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029991 313043888 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320795 CS(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCC#CCO)cc1)C(=O)NO InChI=1S/C19H26N4O7S/c1-31(28,29)23-10-8-22(9-11-23)17(19(26)21-27)14-20-18(25)15-4-6-16(7-5-15)30-13-3-2-12-24/h4-7,17,24,27H,8-14H2,1H3,(H,20,25)(H,21,26)/t17-/m0/s1 VGFQYXCZLQMABL-KRWDZBQOSA-N 175084 US9115102, Ex16 Disintegrin and metalloproteinase domain-containing protein 17 35 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175084 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175084&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030087 313043890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320796 COc1ccc(COc2ccc(cc2)C(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)cc1 InChI=1S/C23H30N4O7S/c1-33-19-7-3-17(4-8-19)16-34-20-9-5-18(6-10-20)22(28)24-15-21(23(29)25-30)26-11-13-27(14-12-26)35(2,31)32/h3-10,21,30H,11-16H2,1-2H3,(H,24,28)(H,25,29)/t21-/m0/s1 WBTQQCWOHIJPNS-NRFANRHFSA-N 175085 US9115102, Ex17 Disintegrin and metalloproteinase domain-containing protein 17 70 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175085&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030089 313043891 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320797 CS(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCc2ccncc2)cc1)C(=O)NO InChI=1S/C21H27N5O6S/c1-33(30,31)26-12-10-25(11-13-26)19(21(28)24-29)14-23-20(27)17-2-4-18(5-3-17)32-15-16-6-8-22-9-7-16/h2-9,19,29H,10-15H2,1H3,(H,23,27)(H,24,28)/t19-/m0/s1 LLPCFPKSSILKBR-IBGZPJMESA-N 175086 US9115102, Ex18 Disintegrin and metalloproteinase domain-containing protein 17 99 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175086 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175086&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030088 313043892 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320798 Cc1ccc2ccccc2c1COc1ccc(cc1)C(=O)NC[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C27H32N4O6S/c1-19-7-8-20-5-3-4-6-23(20)24(19)18-37-22-11-9-21(10-12-22)26(32)28-17-25(27(33)29-34)30-13-15-31(16-14-30)38(2,35)36/h3-12,25,34H,13-18H2,1-2H3,(H,28,32)(H,29,33)/t25-/m0/s1 JFMYEFGLQAGVGS-VWLOTQADSA-N 175087 US9115102, Ex19 Disintegrin and metalloproteinase domain-containing protein 17 138 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175087 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175087&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030090 313043893 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320799 CS(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCc2ccnc3ccccc23)cc1)C(=O)NO InChI=1S/C25H29N5O6S/c1-37(34,35)30-14-12-29(13-15-30)23(25(32)28-33)16-27-24(31)18-6-8-20(9-7-18)36-17-19-10-11-26-22-5-3-2-4-21(19)22/h2-11,23,33H,12-17H2,1H3,(H,27,31)(H,28,32)/t23-/m0/s1 YYGQFNAGQSVNOU-QHCPKHFHSA-N 175088 US9115102, Ex21 Disintegrin and metalloproteinase domain-containing protein 17 118 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175088&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030180 313043894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320800 Cc1cc(COc2ccc(cc2)C(=O)NC[C@H](N2CCN(Cc3ccccc3)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C32H35N5O4/c1-23-19-26(28-9-5-6-10-29(28)34-23)22-41-27-13-11-25(12-14-27)31(38)33-20-30(32(39)35-40)37-17-15-36(16-18-37)21-24-7-3-2-4-8-24/h2-14,19,30,40H,15-18,20-22H2,1H3,(H,33,38)(H,35,39)/t30-/m0/s1 ITKDYCRBDBIBLL-PMERELPUSA-N 175089 US9115102, Ex22 Disintegrin and metalloproteinase domain-containing protein 17 79 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175089 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175089&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030181 313043895 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320801 CC(C)S(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C28H35N5O6S/c1-19(2)40(37,38)33-14-12-32(13-15-33)26(28(35)31-36)17-29-27(34)21-8-10-23(11-9-21)39-18-22-16-20(3)30-25-7-5-4-6-24(22)25/h4-11,16,19,26,36H,12-15,17-18H2,1-3H3,(H,29,34)(H,31,35)/t26-/m0/s1 CBGQRMHRHSGYBY-SANMLTNESA-N 175090 US9115102, Ex23 Disintegrin and metalloproteinase domain-containing protein 17 102 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175090 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175090&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030182 313043896 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320802 Cc1cc(COc2ccc(cc2)C(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C26H31N5O6S/c1-18-15-20(22-5-3-4-6-23(22)28-18)17-37-21-9-7-19(8-10-21)25(32)27-16-24(26(33)29-34)30-11-13-31(14-12-30)38(2,35)36/h3-10,15,24,34H,11-14,16-17H2,1-2H3,(H,27,32)(H,29,33)/t24-/m0/s1 PNRXTCCMSJTZGK-DEOSSOPVSA-N 175083 US9115102, Ex14::US9115102, Ex24 Disintegrin and metalloproteinase domain-containing protein 17 88 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175083&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029992 313043889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320803 CCN1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C27H33N5O4/c1-3-31-12-14-32(15-13-31)25(27(34)30-35)17-28-26(33)20-8-10-22(11-9-20)36-18-21-16-19(2)29-24-7-5-4-6-23(21)24/h4-11,16,25,35H,3,12-15,17-18H2,1-2H3,(H,28,33)(H,30,34)/t25-/m0/s1 QOQXNIUJSFOAJO-VWLOTQADSA-N 175092 US9115102, Ex25 Disintegrin and metalloproteinase domain-containing protein 17 45 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175092&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51030183 313043897 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320804 ONC(=O)C(CNC(=O)c1ccc(OCc2c(nn3ccccc23)C(F)(F)F)cc1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C30H31F3N6O4/c31-30(32,33)27-24(25-8-4-5-13-39(25)35-27)20-43-23-11-9-22(10-12-23)28(40)34-18-26(29(41)36-42)38-16-14-37(15-17-38)19-21-6-2-1-3-7-21/h1-13,26,42H,14-20H2,(H,34,40)(H,36,41) PWHWIWBGOFSUOR-UHFFFAOYSA-N 175093 US9115102, Ex27 Disintegrin and metalloproteinase domain-containing protein 17 81 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175093&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 75600335 313043898 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320805 CS(=O)(=O)N1CCN(CC1)[C@@H](CNC(=O)c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1)C(=O)NO InChI=1S/C23H27F3N4O6S/c1-37(34,35)30-12-10-29(11-13-30)20(22(32)28-33)14-27-21(31)17-4-8-19(9-5-17)36-15-16-2-6-18(7-3-16)23(24,25)26/h2-9,20,33H,10-15H2,1H3,(H,27,31)(H,28,32)/t20-/m0/s1 ZOMXHWZMLNNKPG-FQEVSTJZSA-N 175096 US9115102, Ex10 Disintegrin and metalloproteinase domain-containing protein 17 117 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175096&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029988 313043901 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320806 Cc1ccc(COc2ccc(cc2)C(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)cc1 InChI=1S/C23H30N4O6S/c1-17-3-5-18(6-4-17)16-33-20-9-7-19(8-10-20)22(28)24-15-21(23(29)25-30)26-11-13-27(14-12-26)34(2,31)32/h3-10,21,30H,11-16H2,1-2H3,(H,24,28)(H,25,29)/t21-/m0/s1 LZPCXUJRYZHJSN-NRFANRHFSA-N 175094 US9115102, Ex11 Disintegrin and metalloproteinase domain-containing protein 17 95 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175094&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029989 313043899 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320827 CC#CCOc1ccc(cc1)C(=O)NC[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C19H26N4O6S/c1-3-4-13-29-16-7-5-15(6-8-16)18(24)20-14-17(19(25)21-26)22-9-11-23(12-10-22)30(2,27)28/h5-8,17,26H,9-14H2,1-2H3,(H,20,24)(H,21,25)/t17-/m0/s1 GHBQSNPRMVUGFE-KRWDZBQOSA-N 175076 US9115102, Ex2 Disintegrin and metalloproteinase domain-containing protein 17 28 US Patent 10.7270/Q21V5CRV aid1801517 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175076&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029815 313043882 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320828 Cc1cc(COc2ccc(cc2)C(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C26H31N5O6S/c1-18-15-20(22-5-3-4-6-23(22)28-18)17-37-21-9-7-19(8-10-21)25(32)27-16-24(26(33)29-34)30-11-13-31(14-12-30)38(2,35)36/h3-10,15,24,34H,11-14,16-17H2,1-2H3,(H,27,32)(H,29,33)/t24-/m0/s1 PNRXTCCMSJTZGK-DEOSSOPVSA-N 175083 US9115102, Ex14::US9115102, Ex24 Disintegrin and metalloproteinase domain-containing protein 17 35 US Patent 10.7270/Q21V5CRV aid1801517 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175083&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029992 313043889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320829 ONC(=O)C(CNC(=O)c1ccc(OCc2c(nn3ccccc23)C(F)(F)F)cc1)N1CCN(Cc2ccccc2)CC1 InChI=1S/C30H31F3N6O4/c31-30(32,33)27-24(25-8-4-5-13-39(25)35-27)20-43-23-11-9-22(10-12-23)28(40)34-18-26(29(41)36-42)38-16-14-37(15-17-38)19-21-6-2-1-3-7-21/h1-13,26,42H,14-20H2,(H,34,40)(H,36,41) PWHWIWBGOFSUOR-UHFFFAOYSA-N 175093 US9115102, Ex27 Disintegrin and metalloproteinase domain-containing protein 17 81 US Patent 10.7270/Q21V5CRV aid1801517 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175093&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 75600335 313043898 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320830 CC1(C)SCCN(C1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1 InChI=1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21) MAVDNGWEBZTACC-UHFFFAOYSA-N 175095 US9115102, Apratastat Disintegrin and metalloproteinase domain-containing protein 17 5 US Patent 10.7270/Q21V5CRV aid1801517 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175095&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9888017 313043900 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 320794 Cc1cc(COc2ccc(cc2)C(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C26H31N5O6S/c1-18-15-20(22-5-3-4-6-23(22)28-18)17-37-21-9-7-19(8-10-21)25(32)27-16-24(26(33)29-34)30-11-13-31(14-12-30)38(2,35)36/h3-10,15,24,34H,11-14,16-17H2,1-2H3,(H,27,32)(H,29,33)/t24-/m0/s1 PNRXTCCMSJTZGK-DEOSSOPVSA-N 175083 US9115102, Ex14::US9115102, Ex24 Disintegrin and metalloproteinase domain-containing protein 17 35 7.4 US Patent 10.7270/Q21V5CRV aid1801516 US9115102 Chambon, S; Clary, L; Schuppli, M Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175083 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175083&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51029992 313043889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367354 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1 InChI=1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21)/t15-/m0/s1 MAVDNGWEBZTACC-HNNXBMFYSA-N 50181008 (S)-N-hydroxy-4-(4-(4-hydroxybut-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206815::TMI-05::US9266848, Apratastat::US9365529, Apratastat Disintegrin and metalloproteinase domain-containing protein 17 5 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181008&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11452716 104065867 CHEMBL206815 6482 ZINC28571311 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367318 CC#CCOc1ccc(cc1)C(=O)NC[C@H](N1CCCCC1)C(=O)NO InChI=1S/C19H25N3O4/c1-2-3-13-26-16-9-7-15(8-10-16)18(23)20-14-17(19(24)21-25)22-11-5-4-6-12-22/h7-10,17,25H,4-6,11-14H2,1H3,(H,20,23)(H,21,24)/t17-/m0/s1 LFORXWHNWSTJGB-KRWDZBQOSA-N 207963 US9266848, 1 Disintegrin and metalloproteinase domain-containing protein 17 9 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 50990949 322058501 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367319 Cc1cc(COc2ccc(cc2)C(=O)NC[C@H](N2CCCCC2)C(=O)NO)c2ccccc2n1 InChI=1S/C26H30N4O4/c1-18-15-20(22-7-3-4-8-23(22)28-18)17-34-21-11-9-19(10-12-21)25(31)27-16-24(26(32)29-33)30-13-5-2-6-14-30/h3-4,7-12,15,24,33H,2,5-6,13-14,16-17H2,1H3,(H,27,31)(H,29,32)/t24-/m0/s1 UKKMFRSGWXZXCZ-DEOSSOPVSA-N 207964 US9266848, 2 Disintegrin and metalloproteinase domain-containing protein 17 71 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207964&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51034293 322058502 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367320 ONC(=O)[C@H](CNC(=O)c1ccc(OCc2cc(Cl)nc(Cl)c2)cc1)N1CCCCC1 InChI=1S/C21H24Cl2N4O4/c22-18-10-14(11-19(23)25-18)13-31-16-6-4-15(5-7-16)20(28)24-12-17(21(29)26-30)27-8-2-1-3-9-27/h4-7,10-11,17,30H,1-3,8-9,12-13H2,(H,24,28)(H,26,29)/t17-/m0/s1 JZGAMBBGGHNFGW-KRWDZBQOSA-N 207965 US9266848, 3 Disintegrin and metalloproteinase domain-containing protein 17 255 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207965&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 87252119 322058503 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367321 ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)N1CCCCC1 InChI=1S/C27H30N4O4/c32-26(29-18-25(27(33)30-34)31-15-5-2-6-16-31)22-9-11-23(12-10-22)35-19-20-13-14-28-24(17-20)21-7-3-1-4-8-21/h1,3-4,7-14,17,25,34H,2,5-6,15-16,18-19H2,(H,29,32)(H,30,33)/t25-/m0/s1 HMKOPGQRIXEHTH-VWLOTQADSA-N 207966 US9266848, 4 Disintegrin and metalloproteinase domain-containing protein 17 61 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207966&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51034294 322058504 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367322 ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccncc2)cc1)N1CCCCC1 InChI=1S/C21H26N4O4/c26-20(23-14-19(21(27)24-28)25-12-2-1-3-13-25)17-4-6-18(7-5-17)29-15-16-8-10-22-11-9-16/h4-11,19,28H,1-3,12-15H2,(H,23,26)(H,24,27)/t19-/m0/s1 ZTDRQXAWZXLROA-IBGZPJMESA-N 207967 US9266848, 5 Disintegrin and metalloproteinase domain-containing protein 17 108 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207967&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51034295 322058505 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367323 NC(=O)[C@@](O)(CNC(=O)c1ccc(OCc2ccc(cc2)C#N)cc1)N1CCCCC1 InChI=1S/C23H26N4O4/c24-14-17-4-6-18(7-5-17)15-31-20-10-8-19(9-11-20)21(28)26-16-23(30,22(25)29)27-12-2-1-3-13-27/h4-11,30H,1-3,12-13,15-16H2,(H2,25,29)(H,26,28)/t23-/m0/s1 UTUJFHZBCNIXFL-QHCPKHFHSA-N 207968 US9266848, 6 Disintegrin and metalloproteinase domain-containing protein 17 70 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207968&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 67056316 322058506 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367324 Cc1ccc(COc2ccc(cc2)C(=O)NC[C@H](N2CCCCC2)C(=O)NO)c2ccccc12 InChI=1S/C27H31N3O4/c1-19-9-10-21(24-8-4-3-7-23(19)24)18-34-22-13-11-20(12-14-22)26(31)28-17-25(27(32)29-33)30-15-5-2-6-16-30/h3-4,7-14,25,33H,2,5-6,15-18H2,1H3,(H,28,31)(H,29,32)/t25-/m0/s1 WUFXIOKDLJQNIG-VWLOTQADSA-N 207969 US9266848, 7 Disintegrin and metalloproteinase domain-containing protein 17 91 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207969&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51034412 322058507 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367325 ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(Br)c2)cc1)N1CCCCC1 InChI=1S/C21H25BrN4O4/c22-19-12-15(8-9-23-19)14-30-17-6-4-16(5-7-17)20(27)24-13-18(21(28)25-29)26-10-2-1-3-11-26/h4-9,12,18,29H,1-3,10-11,13-14H2,(H,24,27)(H,25,28)/t18-/m0/s1 ZBLIWQSEYJDJIM-SFHVURJKSA-N 207970 US9266848, 8 Disintegrin and metalloproteinase domain-containing protein 17 105 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207970&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51034413 322058508 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367326 ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccncc2)cc1)N1CCOCC1 InChI=1S/C20H24N4O5/c25-19(22-13-18(20(26)23-27)24-9-11-28-12-10-24)16-1-3-17(4-2-16)29-14-15-5-7-21-8-6-15/h1-8,18,27H,9-14H2,(H,22,25)(H,23,26)/t18-/m0/s1 WECXTLRQYURNBC-SFHVURJKSA-N 207971 US9266848, 9 Disintegrin and metalloproteinase domain-containing protein 17 428 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51034414 322058509 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367327 ONC(=O)[C@H](CNC(=O)c1ccc(OCc2ccnc(c2)-c2cccc(c2)C(F)(F)F)cc1)N1CCOCC1 InChI=1S/C27H27F3N4O5/c28-27(29,30)21-3-1-2-20(15-21)23-14-18(8-9-31-23)17-39-22-6-4-19(5-7-22)25(35)32-16-24(26(36)33-37)34-10-12-38-13-11-34/h1-9,14-15,24,37H,10-13,16-17H2,(H,32,35)(H,33,36)/t24-/m0/s1 TUCLSYCPLKVKNT-DEOSSOPVSA-N 207972 US9266848, 10 Disintegrin and metalloproteinase domain-containing protein 17 900 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 87252125 322058510 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 367328 CCN(CC)[C@@H](CNC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H30N4O4/c1-4-29(5-2)23(25(31)28-32)15-26-24(30)18-10-12-20(13-11-18)33-16-19-14-17(3)27-22-9-7-6-8-21(19)22/h6-14,23,32H,4-5,15-16H2,1-3H3,(H,26,30)(H,28,31)/t23-/m0/s1 YWFGTIGZVCACAJ-QHCPKHFHSA-N 207973 US9266848, 11 Disintegrin and metalloproteinase domain-containing protein 17 232 7.4 37.00 C US Patent 10.7270/Q2TM78ZS aid1802272 US9266848 Clary, L; Pascal, J Galderma Research & Development http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=207973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=207973&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51034416 322058511 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 408407 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1 NITYDPDXAAFEIT-DYVFJYSZSA-N 234334 GM6001 Disintegrin and metalloproteinase domain-containing protein 17 317 9 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.487485 10.7270/Q2JM28J1 21406033 aid1802979 Zhao, Y; Yu, J; Gu, J; Huang, W Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234334 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234334&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search GM6 2DW1,2DW0,1PWU,2ERP,2E3X,4PKW 132519 340094323 DB02255 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 408408 ONC(=O)Cc1cc2ccccc2oc1=O InChI=1S/C11H9NO4/c13-10(12-15)6-8-5-7-3-1-2-4-9(7)16-11(8)14/h1-5,15H,6H2,(H,12,13) AUFRSHPKGODFMN-UHFFFAOYSA-N 234335 Inhibitor A Disintegrin and metalloproteinase domain-containing protein 17 175 9 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2010.487485 10.7270/Q2JM28J1 21406033 aid1802979 Zhao, Y; Yu, J; Gu, J; Huang, W Huazhong University of Science and Technology http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=234335 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=234335&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 119084450 340094324 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 413122 N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@H](CCCNC(N)=N)C(O)=O InChI=1S/C33H49N11O6S/c34-22(13-7-15-39-32(35)36)27(45)44-26(19-51)30(48)43-25(18-21-11-5-2-6-12-21)29(47)42-24(17-20-9-3-1-4-10-20)28(46)41-23(31(49)50)14-8-16-40-33(37)38/h1-6,9-12,22-26,51H,7-8,13-19,34H2,(H,41,46)(H,42,47)(H,43,48)(H,44,45)(H,49,50)(H4,35,36,39)(H4,37,38,40)/t22-,23+,24+,25+,26-/m0/s1 JPEJFCANQAANFI-QJEZIUSSSA-N 237177 Arg-Cys-(D-Bip)-(D-Arg) Disintegrin and metalloproteinase domain-containing protein 17 2.0e+4 7.4 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2011.599323 10.7270/Q21835D8 21827363 aid1803129 Qiu, Z; Yan, M; Li, Q; Liu, D; Van den Steen, PE; Wang, M; Opdenakker, G; Hu, J China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237177&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 129012459 340130739 C02248 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 413123 N[C@@H](CCCNC(N)=N)C(=O)N[C@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O InChI=1S/C33H49N11O6S/c34-22(13-7-15-39-32(35)36)27(45)44-26(19-51)30(48)43-25(18-21-11-5-2-6-12-21)29(47)42-24(17-20-9-3-1-4-10-20)28(46)41-23(31(49)50)14-8-16-40-33(37)38/h1-6,9-12,22-26,51H,7-8,13-19,34H2,(H,41,46)(H,42,47)(H,43,48)(H,44,45)(H,49,50)(H4,35,36,39)(H4,37,38,40)/t22-,23-,24-,25-,26+/m0/s1 JPEJFCANQAANFI-WBAQKLHDSA-N 237178 Arg-(D-Cys)-Bip-Arg Disintegrin and metalloproteinase domain-containing protein 17 2.5e+3 7.4 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2011.599323 10.7270/Q21835D8 21827363 aid1803129 Qiu, Z; Yan, M; Li, Q; Liu, D; Van den Steen, PE; Wang, M; Opdenakker, G; Hu, J China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237178 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237178&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 129012460 340130740 C04026 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 413124 C[C@@H](Nc1ccccn1)C(=O)N[C@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CS)C(O)=O InChI=1S/C32H38N6O6S2/c1-20(34-27-14-8-9-15-33-27)28(39)37-25(18-45)31(42)36-23(16-21-10-4-2-5-11-21)29(40)35-24(17-22-12-6-3-7-13-22)30(41)38-26(19-46)32(43)44/h2-15,20,23-26,45-46H,16-19H2,1H3,(H,33,34)(H,35,40)(H,36,42)(H,37,39)(H,38,41)(H,43,44)/t20-,23+,24+,25-,26-/m1/s1 RCOWFLVNGLZXHL-KCQKKKKCSA-N 237179 (D-Pyr)-(D-Cys)-Bip-(D-Cys) Disintegrin and metalloproteinase domain-containing protein 17 6e+2 7.4 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2011.599323 10.7270/Q21835D8 21827363 aid1803129 Qiu, Z; Yan, M; Li, Q; Liu, D; Van den Steen, PE; Wang, M; Opdenakker, G; Hu, J China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237179 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237179&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 129012461 340130741 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 413125 C[C@@H](Nc1ccccn1)C(=O)N[C@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O InChI=1S/C35H45N9O6S/c1-22(40-29-16-8-9-17-38-29)30(45)44-28(21-51)33(48)43-27(20-24-13-6-3-7-14-24)32(47)42-26(19-23-11-4-2-5-12-23)31(46)41-25(34(49)50)15-10-18-39-35(36)37/h2-9,11-14,16-17,22,25-28,51H,10,15,18-21H2,1H3,(H,38,40)(H,41,46)(H,42,47)(H,43,48)(H,44,45)(H,49,50)(H4,36,37,39)/t22-,25+,26+,27+,28-/m1/s1 FXOYJFYAASAICA-HMZHQOCUSA-N 237180 (D-Pyr)-(D-Cys)-Bip-Arg Disintegrin and metalloproteinase domain-containing protein 17 5.5e+3 7.4 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2011.599323 10.7270/Q21835D8 21827363 aid1803129 Qiu, Z; Yan, M; Li, Q; Liu, D; Van den Steen, PE; Wang, M; Opdenakker, G; Hu, J China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237180 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237180&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 129012462 340130742 C04026 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 413126 C[C@@H](Nc1ccccn1)C(=O)N[C@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(O)=O InChI=1S/C35H45N7O6S/c1-23(38-30-17-9-11-19-37-30)31(43)42-29(22-49)34(46)41-28(21-25-14-6-3-7-15-25)33(45)40-27(20-24-12-4-2-5-13-24)32(44)39-26(35(47)48)16-8-10-18-36/h2-7,9,11-15,17,19,23,26-29,49H,8,10,16,18,20-22,36H2,1H3,(H,37,38)(H,39,44)(H,40,45)(H,41,46)(H,42,43)(H,47,48)/t23-,26+,27+,28+,29-/m1/s1 TWMVZPPZEWFNOP-NUKLZVDMSA-N 237181 (D-Pyr)-(D-Cys)-Bip-Lys Disintegrin and metalloproteinase domain-containing protein 17 8e+3 7.4 37.00 C Curated from the literature by BindingDB 10.3109/14756366.2011.599323 10.7270/Q21835D8 21827363 aid1803129 Qiu, Z; Yan, M; Li, Q; Liu, D; Van den Steen, PE; Wang, M; Opdenakker, G; Hu, J China Pharmaceutical University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=237181 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=237181&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 129012463 340130743 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411082 CC#CCOc1ccc(cc1)S(=O)(=O)CNCC(N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C19H28N4O7S2/c1-3-4-13-30-16-5-7-17(8-6-16)32(28,29)15-20-14-18(19(24)21-25)22-9-11-23(12-10-22)31(2,26)27/h5-8,18,20,25H,9-15H2,1-2H3,(H,21,24) LVXSNFPFOJZOFN-UHFFFAOYSA-N 113573 US8633196, 1::US9365529, 1 Disintegrin and metalloproteinase domain-containing protein 17 87 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113573 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113573&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 77014286 199995289 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411083 CC#CCOc1ccc(cc1)S(=O)(=O)NC[C@H](N1CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C18H26N4O7S2/c1-3-4-13-29-15-5-7-16(8-6-15)31(27,28)19-14-17(18(23)20-24)21-9-11-22(12-10-21)30(2,25)26/h5-8,17,19,24H,9-14H2,1-2H3,(H,20,23)/t17-/m0/s1 NDILBIRPFZRQSV-KRWDZBQOSA-N 113574 US8633196, 2::US9365529, 2 Disintegrin and metalloproteinase domain-containing protein 17 32 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113574&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849089 199995290 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411084 CS(=O)(=O)N1CCN(CC1)[C@@H](CNCS(=O)(=O)c1ccc(OCc2ccccc2)cc1)C(=O)NO InChI=1S/C22H30N4O7S2/c1-34(29,30)26-13-11-25(12-14-26)21(22(27)24-28)15-23-17-35(31,32)20-9-7-19(8-10-20)33-16-18-5-3-2-4-6-18/h2-10,21,23,28H,11-17H2,1H3,(H,24,27)/t21-/m0/s1 FZUQBSLWAJVSOZ-NRFANRHFSA-N 113576 US8633196, 4::US9365529, 4 Disintegrin and metalloproteinase domain-containing protein 17 497 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113576&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 77014287 199995292 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411085 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C25H31N5O7S2/c1-18-15-19(22-5-3-4-6-23(22)27-18)17-37-20-7-9-21(10-8-20)39(35,36)26-16-24(25(31)28-32)29-11-13-30(14-12-29)38(2,33)34/h3-10,15,24,26,32H,11-14,16-17H2,1-2H3,(H,28,31)/t24-/m0/s1 IVLLKNCAVYHIFI-DEOSSOPVSA-N 113577 US8633196, 14::US8633196, 5::US9365529, 5 Disintegrin and metalloproteinase domain-containing protein 17 21 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849092 199995293 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411086 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cccc3ccccc23)cc1)C(=O)NO InChI=1S/C25H30N4O7S2/c1-37(32,33)29-15-13-28(14-16-29)24(25(30)27-31)17-26-38(34,35)22-11-9-21(10-12-22)36-18-20-7-4-6-19-5-2-3-8-23(19)20/h2-12,24,26,31H,13-18H2,1H3,(H,27,30)/t24-/m0/s1 GMFKQLSOVMGNDE-DEOSSOPVSA-N 113578 US8633196, 6::US9365529, 6 Disintegrin and metalloproteinase domain-containing protein 17 52 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113578&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849198 199995294 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411087 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cccc(c2)C#N)cc1)C(=O)NO InChI=1S/C22H27N5O7S2/c1-35(30,31)27-11-9-26(10-12-27)21(22(28)25-29)15-24-36(32,33)20-7-5-19(6-8-20)34-16-18-4-2-3-17(13-18)14-23/h2-8,13,21,24,29H,9-12,15-16H2,1H3,(H,25,28)/t21-/m0/s1 OIUKNLHRLRYZSP-NRFANRHFSA-N 113580 US8633196, 8::US9365529, 8 Disintegrin and metalloproteinase domain-containing protein 17 127 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113580 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113580&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849199 199995296 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411088 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2ccc(cc2)C#N)cc1)C(=O)NO InChI=1S/C22H27N5O7S2/c1-35(30,31)27-12-10-26(11-13-27)21(22(28)25-29)15-24-36(32,33)20-8-6-19(7-9-20)34-16-18-4-2-17(14-23)3-5-18/h2-9,21,24,29H,10-13,15-16H2,1H3,(H,25,28)/t21-/m0/s1 FRTIGTXSRUVYBM-NRFANRHFSA-N 113581 US8633196, 9::US9365529, 9 Disintegrin and metalloproteinase domain-containing protein 17 147 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113581 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113581&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849200 199995297 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411089 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(CC2)C(=O)OCc2ccccc2)C(=O)NO)c2ccccc2n1 InChI=1S/C32H35N5O7S/c1-23-19-25(28-9-5-6-10-29(28)34-23)22-43-26-11-13-27(14-12-26)45(41,42)33-20-30(31(38)35-40)36-15-17-37(18-16-36)32(39)44-21-24-7-3-2-4-8-24/h2-14,19,30,33,40H,15-18,20-22H2,1H3,(H,35,38)/t30-/m0/s1 WYQFYOPMZXRDFX-PMERELPUSA-N 113582 US8633196, 10::US9365529, 10 Disintegrin and metalloproteinase domain-containing protein 17 47 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113582 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113582&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849201 199995298 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411090 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2ccnc(c2)-c2ccccc2)cc1)C(=O)NO InChI=1S/C26H31N5O7S2/c1-39(34,35)31-15-13-30(14-16-31)25(26(32)29-33)18-28-40(36,37)23-9-7-22(8-10-23)38-19-20-11-12-27-24(17-20)21-5-3-2-4-6-21/h2-12,17,25,28,33H,13-16,18-19H2,1H3,(H,29,32)/t25-/m0/s1 NVTYXFMRFDNMOE-VWLOTQADSA-N 113583 US8633196, 11::US9365529, 11 Disintegrin and metalloproteinase domain-containing protein 17 24 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113583 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113583&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849202 199995299 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411091 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCNCC2)C(=O)NO)c2ccccc2n1 InChI=1S/C24H29N5O5S/c1-17-14-18(21-4-2-3-5-22(21)27-17)16-34-19-6-8-20(9-7-19)35(32,33)26-15-23(24(30)28-31)29-12-10-25-11-13-29/h2-9,14,23,25-26,31H,10-13,15-16H2,1H3,(H,28,30)/t23-/m0/s1 NITVPFGZLZEXAL-QHCPKHFHSA-N 113584 US8633196, 13::US9365529, 13 Disintegrin and metalloproteinase domain-containing protein 17 108 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113584 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113584&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847348 199995300 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411092 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C25H31N5O7S2/c1-18-15-19(22-5-3-4-6-23(22)27-18)17-37-20-7-9-21(10-8-20)39(35,36)26-16-24(25(31)28-32)29-11-13-30(14-12-29)38(2,33)34/h3-10,15,24,26,32H,11-14,16-17H2,1-2H3,(H,28,31)/t24-/m0/s1 IVLLKNCAVYHIFI-DEOSSOPVSA-N 113577 US8633196, 14::US8633196, 5::US9365529, 5 Disintegrin and metalloproteinase domain-containing protein 17 64 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49849092 199995293 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411093 CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2ccnc3ccccc23)cc1)C(=O)NO InChI=1S/C24H29N5O7S2/c1-37(32,33)29-14-12-28(13-15-29)23(24(30)27-31)16-26-38(34,35)20-8-6-19(7-9-20)36-17-18-10-11-25-22-5-3-2-4-21(18)22/h2-11,23,26,31H,12-17H2,1H3,(H,27,30)/t23-/m0/s1 YYKOFMPNFHGOJF-QHCPKHFHSA-N 113586 US8633196, 16::US9365529, 16 Disintegrin and metalloproteinase domain-containing protein 17 168 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113586 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113586&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847351 199995302 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411094 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccccc3)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C31H35N5O5S/c1-23-19-25(28-9-5-6-10-29(28)33-23)22-41-26-11-13-27(14-12-26)42(39,40)32-20-30(31(37)34-38)36-17-15-35(16-18-36)21-24-7-3-2-4-8-24/h2-14,19,30,32,38H,15-18,20-22H2,1H3,(H,34,37)/t30-/m0/s1 XPGFEPBGGOVQAJ-PMERELPUSA-N 113587 US8633196, 17::US9365529, 17 Disintegrin and metalloproteinase domain-containing protein 17 62 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113587 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113587&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847473 199995303 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411095 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(F)cc3)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C31H34FN5O5S/c1-22-18-24(28-4-2-3-5-29(28)34-22)21-42-26-10-12-27(13-11-26)43(40,41)33-19-30(31(38)35-39)37-16-14-36(15-17-37)20-23-6-8-25(32)9-7-23/h2-13,18,30,33,39H,14-17,19-21H2,1H3,(H,35,38)/t30-/m0/s1 UWCNFKCKFSEPKW-PMERELPUSA-N 113588 US8633196, 18::US9365529, 18 Disintegrin and metalloproteinase domain-containing protein 17 67 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113588 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113588&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847471 199995304 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411096 CCN1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C26H33N5O5S/c1-3-30-12-14-31(15-13-30)25(26(32)29-33)17-27-37(34,35)22-10-8-21(9-11-22)36-18-20-16-19(2)28-24-7-5-4-6-23(20)24/h4-11,16,25,27,33H,3,12-15,17-18H2,1-2H3,(H,29,32)/t25-/m0/s1 UFNKXVJYCDHZQW-VWLOTQADSA-N 113589 US8633196, 19::US9365529, 19 Disintegrin and metalloproteinase domain-containing protein 17 41 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113589 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113589&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847472 199995305 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411097 Cc1ccc(CN2CCN(CC2)[C@@H](CNS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(=O)NO)cc1 InChI=1S/C32H37N5O5S/c1-23-7-9-25(10-8-23)21-36-15-17-37(18-16-36)31(32(38)35-39)20-33-43(40,41)28-13-11-27(12-14-28)42-22-26-19-24(2)34-30-6-4-3-5-29(26)30/h3-14,19,31,33,39H,15-18,20-22H2,1-2H3,(H,35,38)/t31-/m0/s1 OEKBBQNVZPGHFU-HKBQPEDESA-N 113590 US8633196, 21::US9365529, 21 Disintegrin and metalloproteinase domain-containing protein 17 63 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113590 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113590&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847597 199995306 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411098 CC(C)C(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C28H35N5O6S/c1-19(2)28(35)33-14-12-32(13-15-33)26(27(34)31-36)17-29-40(37,38)23-10-8-22(9-11-23)39-18-21-16-20(3)30-25-7-5-4-6-24(21)25/h4-11,16,19,26,29,36H,12-15,17-18H2,1-3H3,(H,31,34)/t26-/m0/s1 NVPQXUAYORUQIU-SANMLTNESA-N 113591 US8633196, 23::US9365529, 23 Disintegrin and metalloproteinase domain-containing protein 17 53 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113591 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113591&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847599 199995307 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411099 CC(C)CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C28H37N5O7S2/c1-20(2)19-41(36,37)33-14-12-32(13-15-33)27(28(34)31-35)17-29-42(38,39)24-10-8-23(9-11-24)40-18-22-16-21(3)30-26-7-5-4-6-25(22)26/h4-11,16,20,27,29,35H,12-15,17-19H2,1-3H3,(H,31,34)/t27-/m0/s1 IUVIWMVVODOSQU-MHZLTWQESA-N 113592 US8633196, 24::US9365529, 24 Disintegrin and metalloproteinase domain-containing protein 17 86 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113592&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847600 199995308 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411100 CC(C)S(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C27H35N5O7S2/c1-19(2)41(37,38)32-14-12-31(13-15-32)26(27(33)30-34)17-28-40(35,36)23-10-8-22(9-11-23)39-18-21-16-20(3)29-25-7-5-4-6-24(21)25/h4-11,16,19,26,28,34H,12-15,17-18H2,1-3H3,(H,30,33)/t26-/m0/s1 AHKGXKHDKHAJDE-SANMLTNESA-N 113593 US8633196, 26::US9365529, 26 Disintegrin and metalloproteinase domain-containing protein 17 33 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113593&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49837937 199995309 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411146 Cc1cc(COc2ccc(cc2)S(=O)(=O)NC[C@H](N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)C(=O)NO)c2ccccc2n1 InChI=1S/C32H34F3N5O5S/c1-22-18-24(28-4-2-3-5-29(28)37-22)21-45-26-10-12-27(13-11-26)46(43,44)36-19-30(31(41)38-42)40-16-14-39(15-17-40)20-23-6-8-25(9-7-23)32(33,34)35/h2-13,18,30,36,42H,14-17,19-21H2,1H3,(H,38,41)/t30-/m0/s1 JCBLZSWVZUEGKV-PMERELPUSA-N 235932 US9365529, 20 Disintegrin and metalloproteinase domain-containing protein 17 140 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=235932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=235932&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847474 340129524 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411147 CC(C)CS(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C28H37N5O7S2/c1-20(2)19-41(36,37)33-14-12-32(13-15-33)27(28(34)31-35)17-29-42(38,39)24-10-8-23(9-11-24)40-18-22-16-21(3)30-26-7-5-4-6-25(22)26/h4-11,16,20,27,29,35H,12-15,17-19H2,1-3H3,(H,31,34)/t27-/m0/s1 IUVIWMVVODOSQU-MHZLTWQESA-N 113592 US8633196, 24::US9365529, 24 Disintegrin and metalloproteinase domain-containing protein 17 16 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113592 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113592&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49847600 199995308 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411148 CC(C)S(=O)(=O)N1CCN(CC1)[C@@H](CNS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C27H35N5O7S2/c1-19(2)41(37,38)32-14-12-31(13-15-32)26(27(33)30-34)17-28-40(35,36)23-10-8-22(9-11-23)39-18-21-16-20(3)29-25-7-5-4-6-24(21)25/h4-11,16,19,26,28,34H,12-15,17-18H2,1-3H3,(H,30,33)/t26-/m0/s1 AHKGXKHDKHAJDE-SANMLTNESA-N 113593 US8633196, 26::US9365529, 26 Disintegrin and metalloproteinase domain-containing protein 17 16 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=113593 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=113593&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49837937 199995309 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 411149 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1 InChI=1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21)/t15-/m0/s1 MAVDNGWEBZTACC-HNNXBMFYSA-N 50181008 (S)-N-hydroxy-4-(4-(4-hydroxybut-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206815::TMI-05::US9266848, Apratastat::US9365529, Apratastat Disintegrin and metalloproteinase domain-containing protein 17 5 7.4 37.00 C US Patent 10.7270/Q29W0DC8 aid1803060 US9365529 Clary, L; Chambon, S; Chantalat, L; Rosignoli, C; Roye, O; Pascal, J; Schuppli-Nollet, M GALDERMA RESEARCH & DEVLOPMENT http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181008&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11452716 104065867 CHEMBL206815 6482 ZINC28571311 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015624 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3cc(OC)c(OC)c(OC)c3)C(=O)N1)C(=O)NO)cc2 InChI=1S/C30H41N3O8/c1-31-30(36)24-16-19-11-13-21(14-12-19)41-15-6-5-9-23(29(35)33-37)22(28(34)32-24)10-7-8-20-17-25(38-2)27(40-4)26(18-20)39-3/h11-14,17-18,22-24,37H,5-10,15-16H2,1-4H3,(H,31,36)(H,32,34)(H,33,35)/t22-,23+,24+/m1/s1 XSFCSVRJCFLQJI-SGNDLWITSA-N 50106023 (7S,8R,11S)-9-Oxo-8-[3-(3,4,5-trimethoxy-phenyl)-propyl]-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL95718 Disintegrin and metalloproteinase domain-containing protein 17 7.6 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106023&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330130 104001603 CHEMBL95718 ZINC26731624 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015625 COc1cc(CCC[C@@H]2[C@H](CCCCOc3ccc(C[C@H](NC2=O)C(=O)c2ccccc2)cc3)C(=O)NO)cc(OC)c1 InChI=1S/C34H40N2O7/c1-41-27-19-24(20-28(22-27)42-2)9-8-13-29-30(34(39)36-40)12-6-7-18-43-26-16-14-23(15-17-26)21-31(35-33(29)38)32(37)25-10-4-3-5-11-25/h3-5,10-11,14-17,19-20,22,29-31,40H,6-9,12-13,18,21H2,1-2H3,(H,35,38)(H,36,39)/t29-,30+,31+/m1/s1 NUWGCPAPIJNAPL-AYQJTBPPSA-N 50106019 (7S,8R,11S)-11-benzoyl-8-[3-(3,5-dimethoxy-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7-carboxylic acid hydroxyamide::CHEMBL99318 Disintegrin and metalloproteinase domain-containing protein 17 2900 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106019&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11758099 104001599 CHEMBL99318 ZINC26741176 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015626 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2cccnc2)cc1 InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(10-11-27-18)28(24,25)15-7-5-13(6-8-15)26-14-4-3-9-19-12-14/h3-9,12,16,23H,10-11H2,1-2H3,(H,20,22)/t16-/m0/s1 YTRMRJDVKQXSIU-INIZCTEOSA-N 50106026 (S)-2,2-Dimethyl-4-[4-(pyridin-3-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL318484 Disintegrin and metalloproteinase domain-containing protein 17 8600 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106026&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330198 104001606 CHEMBL318484 ZINC26739271 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015627 COCCOc1cc(CCC[C@@H]2[C@H](CCCCOc3ccc(C[C@H](NC2=O)C(=O)c2ccccc2)cc3)C(=O)NO)cc(OC)c1 InChI=1S/C36H44N2O8/c1-43-19-20-46-30-22-26(21-29(24-30)44-2)9-8-13-31-32(36(41)38-42)12-6-7-18-45-28-16-14-25(15-17-28)23-33(37-35(31)40)34(39)27-10-4-3-5-11-27/h3-5,10-11,14-17,21-22,24,31-33,42H,6-9,12-13,18-20,23H2,1-2H3,(H,37,40)(H,38,41)/t31-,32+,33+/m1/s1 SMNQMEVQCDUWFV-CEUYOYMZSA-N 50106032 (7S,8R,11S)-11-Benzoyl-8-{3-[3-methoxy-5-(2-methoxy-ethoxy)-phenyl]-propyl}-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7-carboxylic acid hydroxyamide::CHEMBL316725 Disintegrin and metalloproteinase domain-containing protein 17 15000 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106032&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330197 104001612 CHEMBL316725 ZINC26740779 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015628 ONC(=O)[C@H]1CCCCOc2ccc(C[C@H](NC(=O)[C@@H]1CCCc1cc(Br)cc(Br)c1)C(=O)c1ccccc1)cc2 InChI=1S/C32H34Br2N2O5/c33-24-17-22(18-25(34)20-24)7-6-11-27-28(32(39)36-40)10-4-5-16-41-26-14-12-21(13-15-26)19-29(35-31(27)38)30(37)23-8-2-1-3-9-23/h1-3,8-9,12-15,17-18,20,27-29,40H,4-7,10-11,16,19H2,(H,35,38)(H,36,39)/t27-,28+,29+/m1/s1 IGKZHEJCICMYIH-ULNSLHSMSA-N 50106029 (7S,8R,11S)-11-Benzoyl-8-[3-(3,5-dibromo-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7-carboxylic acid hydroxyamide::CHEMBL98304 Disintegrin and metalloproteinase domain-containing protein 17 >5000 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106029&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10055393 104001609 CHEMBL98304 ZINC26740784 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015631 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3ccc(Cl)cc3)C(=O)N1)C(=O)NO)cc2 InChI=1S/C27H34ClN3O5/c1-29-27(34)24-17-19-10-14-21(15-11-19)36-16-3-2-6-23(26(33)31-35)22(25(32)30-24)7-4-5-18-8-12-20(28)13-9-18/h8-15,22-24,35H,2-7,16-17H2,1H3,(H,29,34)(H,30,32)(H,31,33)/t22-,23+,24+/m1/s1 NMAKKNGSMZZSBP-SGNDLWITSA-N 50106022 (7S,8R,11S)-8-[3-(4-chloro-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL318860 Disintegrin and metalloproteinase domain-containing protein 17 440 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106022&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330119 104001602 CHEMBL318860 ZINC26740343 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015637 COc1cc(Oc2ccc(cc2)S(=O)(=O)CC(C)C(=O)NO)cc(OC)c1OC InChI=1S/C19H23NO8S/c1-12(19(21)20-22)11-29(23,24)15-7-5-13(6-8-15)28-14-9-16(25-2)18(27-4)17(10-14)26-3/h5-10,12,22H,11H2,1-4H3,(H,20,21) LUOBAMXDTNOZAD-UHFFFAOYSA-N 50106017 CHEMBL421009::N-Hydroxy-2-methyl-3-[4-(3,4,5-trimethoxy-phenoxy)-benzenesulfonyl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 41000 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106017&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910282 104001597 CHEMBL421009 ZINC26739689 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015655 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3ccc(OC)c(OC)c3)C(=O)N1)C(=O)NO)cc2 InChI=1S/C29H39N3O7/c1-30-29(35)24-17-20-10-13-21(14-11-20)39-16-5-4-8-23(28(34)32-36)22(27(33)31-24)9-6-7-19-12-15-25(37-2)26(18-19)38-3/h10-15,18,22-24,36H,4-9,16-17H2,1-3H3,(H,30,35)(H,31,33)(H,32,34)/t22-,23+,24+/m1/s1 WFARRRAQEGQWNJ-SGNDLWITSA-N 50106027 (7S,8R,11S)-8-[3-(3,4-dimethoxy-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL318005 Disintegrin and metalloproteinase domain-containing protein 17 5.2 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106027&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330131 104001607 CHEMBL318005 ZINC26731627 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015670 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO InChI=1S/C21H21N3O5S/c1-15-5-3-7-19(21(25)23-26)20(15)24(14-16-6-4-12-22-13-16)30(27,28)18-10-8-17(29-2)9-11-18/h3-13,26H,14H2,1-2H3,(H,23,25) AINJYWXKBKRQSX-UHFFFAOYSA-N 50096463 CHEMBL70176::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-3-methylbenzamide Disintegrin and metalloproteinase domain-containing protein 17 356 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096463&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search WAY 1FM1,1FLS 4368 103993979 CHEMBL70176 DB02071 ZINC00602968 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50021669 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO InChI=1S/C22H27N3O6S/c1-15-6-4-5-7-18(15)14-31-19-8-10-20(11-9-19)32(29,30)25-13-12-24(17(3)26)16(2)21(25)22(27)23-28/h4-11,16,21,28H,12-14H2,1-3H3,(H,23,27)/t16-,21+/m0/s1 SBPPAFQZTZUQSW-HRAATJIYSA-N 50132632 (2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL110576 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132632&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9804342 104023615 CHEMBL110576 ZINC13539427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50021674 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1)C(=O)NO InChI=1S/C21H24FN3O6S/c1-14-20(21(27)23-28)25(12-11-24(14)15(2)26)32(29,30)19-9-7-18(8-10-19)31-13-16-3-5-17(22)6-4-16/h3-10,14,20,28H,11-13H2,1-2H3,(H,23,27)/t14-,20+/m0/s1 RSGVYIJLQVPSNJ-VBKZILBWSA-N 50132620 (2R,3S)-4-Acetyl-1-[4-(4-fluoro-benzyloxy)-benzenesulfonyl]-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL110591 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132620&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339543 104023603 CHEMBL110591 ZINC13539436 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50021676 CCOC(=O)N1CCN([C@H]([C@@H]1C)C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1 InChI=1S/C23H29N3O7S/c1-4-32-23(28)25-13-14-26(21(17(25)3)22(27)24-29)34(30,31)20-11-9-19(10-12-20)33-15-18-8-6-5-7-16(18)2/h5-12,17,21,29H,4,13-15H2,1-3H3,(H,24,27)/t17-,21+/m0/s1 FPHXOEUJYCDFQF-LAUBAEHRSA-N 50132621 (2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1-carboxylic acid ethyl ester::CHEMBL109267 Disintegrin and metalloproteinase domain-containing protein 17 3000 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132621&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339444 104023604 CHEMBL109267 ZINC13553167 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50021678 CC(C)NC(=O)N1CCN([C@H]([C@@H]1C)C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1 InChI=1S/C24H32N4O6S/c1-16(2)25-24(30)27-13-14-28(22(18(27)4)23(29)26-31)35(32,33)21-11-9-20(10-12-21)34-15-19-8-6-5-7-17(19)3/h5-12,16,18,22,31H,13-15H2,1-4H3,(H,25,30)(H,26,29)/t18-,22+/m0/s1 GCDCQOTVUSLXRJ-PGRDOPGGSA-N 50132638 (2S,3R)-2-Methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1,3-dicarboxylic acid 3-hydroxyamide 1-isopropylamide::CHEMBL111068 Disintegrin and metalloproteinase domain-containing protein 17 34 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132638&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339452 104023621 CHEMBL111068 ZINC13553166 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50021679 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2cccnc2C)cc1)C(=O)NO InChI=1S/C21H26N4O6S/c1-14-17(5-4-10-22-14)13-31-18-6-8-19(9-7-18)32(29,30)25-12-11-24(16(3)26)15(2)20(25)21(27)23-28/h4-10,15,20,28H,11-13H2,1-3H3,(H,23,27)/t15-,20+/m0/s1 HEJQAFMDGAOYSZ-MGPUTAFESA-N 50132634 (2R,3S)-4-Acetyl-3-methyl-1-[4-(2-methyl-pyridin-3-ylmethoxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL110211 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132634&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339448 104023617 CHEMBL110211 ZINC13553161 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065451 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1 InChI=1S/C20H23FN2O6S/c1-20(25)11-2-12-23(18(20)19(24)22-26)30(27,28)17-9-7-16(8-10-17)29-13-14-3-5-15(21)6-4-14/h3-10,18,25-26H,2,11-13H2,1H3,(H,22,24)/t18-,20+/m0/s1 KPWHSOUKRWDBAT-AZUAARDMSA-N 50168748 (2R,3R)-1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL183995 Disintegrin and metalloproteinase domain-containing protein 17 7.2 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168748&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44394426 104053709 CHEMBL183995 ZINC11536252 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065455 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccc3ccncc23)cc1 InChI=1S/C23H25N3O6S/c1-23(28)11-3-13-26(21(23)22(27)25-29)33(30,31)19-8-6-18(7-9-19)32-15-17-5-2-4-16-10-12-24-14-20(16)17/h2,4-10,12,14,21,28-29H,3,11,13,15H2,1H3,(H,25,27)/t21-,23+/m0/s1 GQVOKPKZCNLEIK-JTHBVZDNSA-N 50168756 (2R,3R)-3-Hydroxy-1-[4-(isoquinolin-8-ylmethoxy)-benzenesulfonyl]-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL436277 Disintegrin and metalloproteinase domain-containing protein 17 2.5 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168756 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168756&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395976 104053717 CHEMBL436277 ZINC28387816 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065459 Cc1ccc(F)cc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO InChI=1S/C21H25FN2O6S/c1-14-4-5-16(22)12-15(14)13-30-17-6-8-18(9-7-17)31(28,29)24-11-3-10-21(2,26)19(24)20(25)23-27/h4-9,12,19,26-27H,3,10-11,13H2,1-2H3,(H,23,25)/t19-,21+/m0/s1 UTAGRFZAWOLQHO-PZJWPPBQSA-N 50168738 (2R,3R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL186500 Disintegrin and metalloproteinase domain-containing protein 17 1.9 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168738&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395271 104053699 CHEMBL186500 ZINC28394199 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065460 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cnccn2)cc1 InChI=1S/C18H22N4O6S/c1-18(24)7-2-10-22(16(18)17(23)21-25)29(26,27)15-5-3-14(4-6-15)28-12-13-11-19-8-9-20-13/h3-6,8-9,11,16,24-25H,2,7,10,12H2,1H3,(H,21,23)/t16-,18+/m0/s1 GVLVYQFIEXXQOS-FUHWJXTLSA-N 50168750 (2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyrazin-2-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187141 Disintegrin and metalloproteinase domain-containing protein 17 60 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168750&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395454 104053711 CHEMBL187141 ZINC28393092 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065509 Cc1c(F)cccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO InChI=1S/C21H25FN2O6S/c1-14-15(5-3-6-18(14)22)13-30-16-7-9-17(10-8-16)31(28,29)24-12-4-11-21(2,26)19(24)20(25)23-27/h3,5-10,19,26-27H,4,11-13H2,1-2H3,(H,23,25)/t19-,21+/m0/s1 NOBVVTLEQRHRBY-PZJWPPBQSA-N 50168743 (2R,3R)-1-[4-(3-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL363126 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168743&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395434 104053704 CHEMBL363126 ZINC28391988 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065510 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccc3cccnc23)cc1 InChI=1S/C23H25N3O6S/c1-23(28)12-4-14-26(21(23)22(27)25-29)33(30,31)19-10-8-18(9-11-19)32-15-17-6-2-5-16-7-3-13-24-20(16)17/h2-3,5-11,13,21,28-29H,4,12,14-15H2,1H3,(H,25,27)/t21-,23+/m0/s1 CSQCYVHPHVXICP-JTHBVZDNSA-N 50168742 (2R,3R)-3-Hydroxy-3-methyl-1-[4-(quinolin-8-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL446697 Disintegrin and metalloproteinase domain-containing protein 17 0.48 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168742&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395935 104053703 CHEMBL446697 ZINC28396889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065511 COc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO InChI=1S/C21H26N2O7S/c1-21(25)12-5-13-23(19(21)20(24)22-26)31(27,28)17-10-8-16(9-11-17)30-14-15-6-3-4-7-18(15)29-2/h3-4,6-11,19,25-26H,5,12-14H2,1-2H3,(H,22,24)/t19-,21+/m0/s1 NFUSRQFYPZGOLU-PZJWPPBQSA-N 50168744 (2R,3R)-3-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benzenesulfonyl]-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187852 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168744&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395069 104053705 CHEMBL187852 ZINC28389241 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065512 Cc1cc(F)ccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO InChI=1S/C21H25FN2O6S/c1-14-12-16(22)5-4-15(14)13-30-17-6-8-18(9-7-17)31(28,29)24-11-3-10-21(2,26)19(24)20(25)23-27/h4-9,12,19,26-27H,3,10-11,13H2,1-2H3,(H,23,25)/t19-,21+/m0/s1 ZHCXOELPVFPGHI-PZJWPPBQSA-N 50168741 (2R,3R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL365283 Disintegrin and metalloproteinase domain-containing protein 17 2.5 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168741&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9846676 104053702 CHEMBL365283 ZINC13561011 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065513 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccnc(Cl)c2)cc1 InChI=1S/C19H22ClN3O6S/c1-19(25)8-2-10-23(17(19)18(24)22-26)30(27,28)15-5-3-14(4-6-15)29-12-13-7-9-21-16(20)11-13/h3-7,9,11,17,25-26H,2,8,10,12H2,1H3,(H,22,24)/t17-,19+/m0/s1 KHAOJBRQDUCAFK-PKOBYXMFSA-N 50168749 (2R,3R)-1-[4-(2-Chloro-pyridin-4-ylmethoxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187474 Disintegrin and metalloproteinase domain-containing protein 17 6.5 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168749&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44396001 104053710 CHEMBL187474 ZINC28455247 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065514 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C#N)cc1 InChI=1S/C21H23N3O6S/c1-21(26)11-4-12-24(19(21)20(25)23-27)31(28,29)18-9-7-17(8-10-18)30-14-16-6-3-2-5-15(16)13-22/h2-3,5-10,19,26-27H,4,11-12,14H2,1H3,(H,23,25)/t19-,21+/m0/s1 BMHWXBBJSOMNRF-PZJWPPBQSA-N 50168759 (2R,3R)-1-[4-(2-Cyano-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL426975 Disintegrin and metalloproteinase domain-containing protein 17 100 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168759 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168759&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395269 104053720 CHEMBL426975 ZINC28393721 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065519 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccc(F)c2)cc1 InChI=1S/C20H23FN2O6S/c1-20(25)10-3-11-23(18(20)19(24)22-26)30(27,28)17-8-6-16(7-9-17)29-13-14-4-2-5-15(21)12-14/h2,4-9,12,18,25-26H,3,10-11,13H2,1H3,(H,22,24)/t18-,20+/m0/s1 BXQLLVHURXNRLY-AZUAARDMSA-N 50168739 (2R,3R)-1-[4-(3-Fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL369115 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168739&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44394819 104053700 CHEMBL369115 ZINC28362053 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065521 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccncc2)cc1 InChI=1S/C19H23N3O6S/c1-19(24)9-2-12-22(17(19)18(23)21-25)29(26,27)16-5-3-15(4-6-16)28-13-14-7-10-20-11-8-14/h3-8,10-11,17,24-25H,2,9,12-13H2,1H3,(H,21,23)/t17-,19+/m0/s1 DOOZILOLHOKUGO-PKOBYXMFSA-N 50168754 (2R,3R)-3-Hydroxy-3-methyl-1-[4-(pyridin-4-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL365247 Disintegrin and metalloproteinase domain-containing protein 17 7.1 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168754&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395643 104053715 CHEMBL365247 ZINC28394277 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065522 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccc(Cl)c2)cc1 InChI=1S/C20H23ClN2O6S/c1-20(25)10-3-11-23(18(20)19(24)22-26)30(27,28)17-8-6-16(7-9-17)29-13-14-4-2-5-15(21)12-14/h2,4-9,12,18,25-26H,3,10-11,13H2,1H3,(H,22,24)/t18-,20+/m0/s1 LOQCMKWGWBMVPA-AZUAARDMSA-N 50168746 (2R,3R)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187245 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168746&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395030 104053707 CHEMBL187245 ZINC28392645 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065524 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2Cl)cc1 InChI=1S/C20H23ClN2O6S/c1-20(25)11-4-12-23(18(20)19(24)22-26)30(27,28)16-9-7-15(8-10-16)29-13-14-5-2-3-6-17(14)21/h2-3,5-10,18,25-26H,4,11-13H2,1H3,(H,22,24)/t18-,20+/m0/s1 NIBQFPHLKYOWJP-AZUAARDMSA-N 50168745 CHEMBL183474::i(2R,3R)-1-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide Disintegrin and metalloproteinase domain-containing protein 17 8.3 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168745&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44394916 104053706 CHEMBL183474 ZINC28383143 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065525 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2F)cc1 InChI=1S/C20H23FN2O6S/c1-20(25)11-4-12-23(18(20)19(24)22-26)30(27,28)16-9-7-15(8-10-16)29-13-14-5-2-3-6-17(14)21/h2-3,5-10,18,25-26H,4,11-13H2,1H3,(H,22,24)/t18-,20+/m0/s1 DIHHYKCLOAQWIB-AZUAARDMSA-N 50168753 (2R,3R)-1-[4-(2-Fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL182306 Disintegrin and metalloproteinase domain-containing protein 17 33 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168753&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44394994 104053714 CHEMBL182306 ZINC28365004 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065516 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(Cl)cc2F)cc1 InChI=1S/C20H22ClFN2O6S/c1-20(26)9-2-10-24(18(20)19(25)23-27)31(28,29)16-7-5-15(6-8-16)30-12-13-3-4-14(21)11-17(13)22/h3-8,11,18,26-27H,2,9-10,12H2,1H3,(H,23,25)/t18-,20+/m0/s1 XMQNILGYVCROEB-AZUAARDMSA-N 50168757 (2R,3R)-1-[4-(4-Chloro-2-fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL360854 Disintegrin and metalloproteinase domain-containing protein 17 73 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168757 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168757&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395660 104053718 CHEMBL360854 ZINC28397887 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065517 Cc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO InChI=1S/C21H26N2O6S/c1-15-6-3-4-7-16(15)14-29-17-8-10-18(11-9-17)30(27,28)23-13-5-12-21(2,25)19(23)20(24)22-26/h3-4,6-11,19,25-26H,5,12-14H2,1-2H3,(H,22,24)/t19-,21+/m0/s1 FYNYGUYHKZWCAU-PZJWPPBQSA-N 50168752 (2R,3R)-3-Hydroxy-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL186663 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168752&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395157 104053713 CHEMBL186663 ZINC28392340 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50065518 Cc1ncccc1COc1ccc(cc1)S(=O)(=O)N1CCC[C@@](C)(O)[C@@H]1C(=O)NO InChI=1S/C20H25N3O6S/c1-14-15(5-3-11-21-14)13-29-16-6-8-17(9-7-16)30(27,28)23-12-4-10-20(2,25)18(23)19(24)22-26/h3,5-9,11,18,25-26H,4,10,12-13H2,1-2H3,(H,22,24)/t18-,20+/m0/s1 OIJUXVJLPZUPIP-AZUAARDMSA-N 50168747 (2R,3R)-3-Hydroxy-3-methyl-1-[4-(2-methyl-pyridin-3-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL186743 Disintegrin and metalloproteinase domain-containing protein 17 3.3 ChEMBL 10.1016/j.bmcl.2005.05.037 10.7270/Q25D8RCC 15953722 Noe, MC; Natarajan, V; Snow, SL; Wolf-Gouveia, LA; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Otterness, I; Bliven, MA; Carty, TJ; Barberia, JT; Sweeney, FJ; Liras, JL; Vaughn, M Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168747&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44396048 104053708 CHEMBL186743 ZINC28394319 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50082847 CNC(=O)[C@H](Cc1c[nH]cn1)NC(=O)CN(CCCc1ccccc1)CC(O)=O InChI=1S/C20H27N5O4/c1-21-20(29)17(10-16-11-22-14-23-16)24-18(26)12-25(13-19(27)28)9-5-8-15-6-3-2-4-7-15/h2-4,6-7,11,14,17H,5,8-10,12-13H2,1H3,(H,21,29)(H,22,23)(H,24,26)(H,27,28)/t17-/m0/s1 QEPAXTJXHXPFJN-KRWDZBQOSA-N 50005641 CHEMBL3235416 Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.ejmech.2014.04.009 10.7270/Q27H1M34 24735644 Charton, J; Gauriot, M; Guo, Q; Hennuyer, N; Marechal, X; Dumont, J; Hamdane, M; Pottiez, V; Landry, V; Sperandio, O; Flipo, M; Buee, L; Staels, B; Leroux, F; Tang, WJ; Deprez, B; Deprez-Poulain, R University of Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50005641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50005641&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search MGJ 4GS8 54589400 242056933 CHEMBL3235416 C00615 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50120858 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H27N3O4/c1-16-14-18(21-6-4-5-7-22(21)26-16)15-32-20-10-8-19(9-11-20)25(3)12-13-28(24(25)30)17(2)23(29)27-31/h4-11,14,17,31H,12-13,15H2,1-3H3,(H,27,29)/t17-,25+/m1/s1 YDMIPBHQKFOFQW-NSYGIPOTSA-N 26526 (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide::BMCL181958 Compound 1::CHEMBL148169::IK682 Disintegrin and metalloproteinase domain-containing protein 17 350 ChEMBL 10.1021/jm0255670 10.7270/Q2XP7497 12408705 Duan, JJ; Chen, L; Wasserman, ZR; Lu, Z; Liu, RQ; Covington, MB; Qian, M; Hardman, KD; Magolda, RL; Newton, RC; Christ, DD; Wexler, RR; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26526&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 541 2FV5 6914621 56464963 40083 CHEMBL148169 DB07145 ZINC03820969 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50120815 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2ccncc2)cc1)C(=O)NO InChI=1S/C20H23N3O4/c1-14(18(24)22-26)23-12-9-20(2,19(23)25)16-3-5-17(6-4-16)27-13-15-7-10-21-11-8-15/h3-8,10-11,14,26H,9,12-13H2,1-2H3,(H,22,24)/t14-,20+/m1/s1 XKXZGTYAPMUIFV-VLIAUNLRSA-N 50120699 CHEMBL342076::N-Hydroxy-2-{3-methyl-2-oxo-3-[4-(pyridin-4-ylmethoxy)-phenyl]-pyrrolidin-1-yl}-propionamide Disintegrin and metalloproteinase domain-containing protein 17 5.9 ChEMBL 10.1021/jm0255670 10.7270/Q2XP7497 12408705 Duan, JJ; Chen, L; Wasserman, ZR; Lu, Z; Liu, RQ; Covington, MB; Qian, M; Hardman, KD; Magolda, RL; Newton, RC; Christ, DD; Wexler, RR; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120699&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11824787 104013741 CHEMBL342076 ZINC13491935 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50120816 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2ccnc3ccccc23)cc1)C(=O)NO InChI=1S/C24H25N3O4/c1-16(22(28)26-30)27-14-12-24(2,23(27)29)18-7-9-19(10-8-18)31-15-17-11-13-25-21-6-4-3-5-20(17)21/h3-11,13,16,30H,12,14-15H2,1-2H3,(H,26,28)/t16-,24+/m1/s1 FFWNQKAKLAZUFB-GYCJOSAFSA-N 50120698 CHEMBL148351::N-Hydroxy-2-{3-methyl-2-oxo-3-[4-(quinolin-4-ylmethoxy)-phenyl]-pyrrolidin-1-yl}-propionamide Disintegrin and metalloproteinase domain-containing protein 17 2.3 ChEMBL 10.1021/jm0255670 10.7270/Q2XP7497 12408705 Duan, JJ; Chen, L; Wasserman, ZR; Lu, Z; Liu, RQ; Covington, MB; Qian, M; Hardman, KD; Magolda, RL; Newton, RC; Christ, DD; Wexler, RR; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120698&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11729454 104013740 CHEMBL148351 ZINC13491938 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122001 COc1cc(COc2ccc3c(NCCN([C@H](C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C20H25N3O7S/c1-13(20(24)22-25)23-7-6-21-18-11-15(4-5-19(18)31(23,26)27)30-12-14-8-16(28-2)10-17(9-14)29-3/h4-5,8-11,13,21,25H,6-7,12H2,1-3H3,(H,22,24)/t13-/m1/s1 APCYYZKHCZUJGB-CYBMUJFWSA-N 50127469 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL51658 Disintegrin and metalloproteinase domain-containing protein 17 770 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127469&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10961382 104019360 CHEMBL51658 ZINC13518139 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122008 COc1cc(COc2ccc3c(NCCN([C@H](CCCCNS(C)(=O)=O)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C24H34N4O9S2/c1-35-19-12-17(13-20(14-19)36-2)16-37-18-7-8-23-21(15-18)25-10-11-28(39(23,33)34)22(24(29)27-30)6-4-5-9-26-38(3,31)32/h7-8,12-15,22,25-26,30H,4-6,9-11,16H2,1-3H3,(H,27,29)/t22-/m1/s1 DNEUAPIVDBXPFN-JOCHJYFZSA-N 50127472 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-6-methanesulfonylamino-hexanoic acid hydroxyamide::CHEMBL416306 Disintegrin and metalloproteinase domain-containing protein 17 38000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9960075 104019363 CHEMBL416306 ZINC29483126 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122009 CC(C)C[C@@H](N1CCNc2cc(O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C14H21N3O5S/c1-9(2)7-12(14(19)16-20)17-6-5-15-11-8-10(18)3-4-13(11)23(17,21)22/h3-4,8-9,12,15,18,20H,5-7H2,1-2H3,(H,16,19)/t12-/m1/s1 KJGJYHSHMUFLOA-GFCCVEGCSA-N 50127478 2-(7-Hydroxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-4-methyl-pentanoic acid hydroxyamide::CHEMBL301157 Disintegrin and metalloproteinase domain-containing protein 17 9500 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127478&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10980832 104019369 CHEMBL301157 ZINC13518150 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122014 C[C@@H](N1CCNc2cc(OCc3cc(C)nc(C)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C19H24N4O5S/c1-12-8-15(9-13(2)21-12)11-28-16-4-5-18-17(10-16)20-6-7-23(29(18,26)27)14(3)19(24)22-25/h4-5,8-10,14,20,25H,6-7,11H2,1-3H3,(H,22,24)/t14-/m1/s1 SZWRRABFHREDHM-CQSZACIVSA-N 50127457 2-[7-(2,6-Dimethyl-pyridin-4-ylmethoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL299796 Disintegrin and metalloproteinase domain-containing protein 17 2900 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127457&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44296974 104019348 CHEMBL299796 ZINC13518147 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122020 COC(=O)CC[C@@H](N1CCNc2cc(OCc3cc(OC)cc(OC)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C23H29N3O9S/c1-32-17-10-15(11-18(12-17)33-2)14-35-16-4-6-21-19(13-16)24-8-9-26(36(21,30)31)20(23(28)25-29)5-7-22(27)34-3/h4,6,10-13,20,24,29H,5,7-9,14H2,1-3H3,(H,25,28)/t20-/m1/s1 YGLAUESDHXXPSW-HXUWFJFHSA-N 50127464 4-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-hydroxycarbamoyl-butyric acid methyl ester::CHEMBL53123 Disintegrin and metalloproteinase domain-containing protein 17 7200 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127464&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11049650 104019355 CHEMBL53123 ZINC13518169 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122155 COC(=O)CCC[C@@H](N1CCNc2cc(OCc3cc(OC)cc(OC)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C24H31N3O9S/c1-33-18-11-16(12-19(13-18)34-2)15-36-17-7-8-22-20(14-17)25-9-10-27(37(22,31)32)21(24(29)26-30)5-4-6-23(28)35-3/h7-8,11-14,21,25,30H,4-6,9-10,15H2,1-3H3,(H,26,29)/t21-/m1/s1 FEFNNGHDRQMMNY-OAQYLSRUSA-N 50127456 5-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-5-hydroxycarbamoyl-pentanoic acid methyl ester::CHEMBL52808 Disintegrin and metalloproteinase domain-containing protein 17 900 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127456&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11734219 104019347 CHEMBL52808 ZINC29485545 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122161 COc1cc(COc2ccc3c(NCCN([C@H](C(C)C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C22H29N3O7S/c1-14(2)21(22(26)24-27)25-8-7-23-19-12-16(5-6-20(19)33(25,28)29)32-13-15-9-17(30-3)11-18(10-15)31-4/h5-6,9-12,14,21,23,27H,7-8,13H2,1-4H3,(H,24,26)/t21-/m1/s1 YHQKAILNGYAYKF-OAQYLSRUSA-N 50127470 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-3-methyl-butyramide::CHEMBL295710 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127470&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10983665 104019361 CHEMBL295710 ZINC13518159 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122163 C[C@@H](N1CCNc2cc(Oc3cccc(c3)[N+]([O-])=O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C17H18N4O7S/c1-11(17(22)19-23)20-8-7-18-15-10-14(5-6-16(15)29(20,26)27)28-13-4-2-3-12(9-13)21(24)25/h2-6,9-11,18,23H,7-8H2,1H3,(H,19,22)/t11-/m1/s1 HEHZCMROVKSJTK-LLVKDONJSA-N 50127460 CHEMBL52659::N-Hydroxy-2-[7-(3-nitro-phenoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 1400 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127460&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11732585 104019351 CHEMBL52659 ZINC13518198 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122164 C[C@@H](N1CCNc2cc(Oc3ccc(cc3)[N+]([O-])=O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C17H18N4O7S/c1-11(17(22)19-23)20-9-8-18-15-10-14(6-7-16(15)29(20,26)27)28-13-4-2-12(3-5-13)21(24)25/h2-7,10-11,18,23H,8-9H2,1H3,(H,19,22)/t11-/m1/s1 KQVRGIRNMDCIEB-LLVKDONJSA-N 50127454 CHEMBL301303::N-Hydroxy-2-[7-(4-nitro-phenoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 15000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127454&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10884337 104019345 CHEMBL301303 ZINC13518201 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122166 CCOc1cc(COc2ccc3c(NCCN([C@H](CCCC(=O)OC)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C26H35N3O9S/c1-4-36-20-13-18(14-21(15-20)37-5-2)17-38-19-9-10-24-22(16-19)27-11-12-29(39(24,33)34)23(26(31)28-32)7-6-8-25(30)35-3/h9-10,13-16,23,27,32H,4-8,11-12,17H2,1-3H3,(H,28,31)/t23-/m1/s1 CZUPUFGAPNROGT-HSZRJFAPSA-N 50127452 5-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-5-hydroxycarbamoyl-pentanoic acid methyl ester::CHEMBL299997 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127452&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10325592 104019343 CHEMBL299997 ZINC29486119 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122168 C[C@@H](N1CCNc2cc(Oc3ccc(cc3)C(F)(F)F)ccc2S1(=O)=O)C(=O)NO InChI=1S/C18H18F3N3O5S/c1-11(17(25)23-26)24-9-8-22-15-10-14(6-7-16(15)30(24,27)28)29-13-4-2-12(3-5-13)18(19,20)21/h2-7,10-11,22,26H,8-9H2,1H3,(H,23,25)/t11-/m1/s1 MGPQYGIRNDXSAA-LLVKDONJSA-N 50127465 2-[1,1-Dioxo-7-(4-trifluoromethyl-phenoxy)-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL298884 Disintegrin and metalloproteinase domain-containing protein 17 840 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10873958 104019356 CHEMBL298884 ZINC13518186 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122169 CCOc1cc(COc2ccc3c(NCCN([C@H](C)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C22H29N3O7S/c1-4-30-18-10-16(11-19(12-18)31-5-2)14-32-17-6-7-21-20(13-17)23-8-9-25(33(21,28)29)15(3)22(26)24-27/h6-7,10-13,15,23,27H,4-5,8-9,14H2,1-3H3,(H,24,26)/t15-/m1/s1 KZZUIFPIPUBRFP-OAHLLOKOSA-N 50127467 2-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL415949 Disintegrin and metalloproteinase domain-containing protein 17 4500 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127467&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10863755 104019358 CHEMBL415949 ZINC13518142 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122171 CCOc1cc(COc2ccc3c(NCCN([C@H](CCCC(=O)OC)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C26H35N3O9S/c1-4-36-20-13-18(14-21(15-20)37-5-2)17-38-19-9-10-24-22(16-19)27-11-12-29(39(24,33)34)23(26(31)28-32)7-6-8-25(30)35-3/h9-10,13-16,23,27,32H,4-8,11-12,17H2,1-3H3,(H,28,31)/t23-/m1/s1 CZUPUFGAPNROGT-HSZRJFAPSA-N 50127452 5-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-5-hydroxycarbamoyl-pentanoic acid methyl ester::CHEMBL299997 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127452&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10325592 104019343 CHEMBL299997 ZINC29486119 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122174 COc1cc(COc2ccc3c(NCCN([C@H](C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C20H25N3O7S/c1-13(20(24)22-25)23-7-6-21-18-11-15(4-5-19(18)31(23,26)27)30-12-14-8-16(28-2)10-17(9-14)29-3/h4-5,8-11,13,21,25H,6-7,12H2,1-3H3,(H,22,24)/t13-/m1/s1 APCYYZKHCZUJGB-CYBMUJFWSA-N 50127469 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL51658 Disintegrin and metalloproteinase domain-containing protein 17 27 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127469&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10961382 104019360 CHEMBL51658 ZINC13518139 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122178 CC(C)C[C@@H](N1CCNc2cc(OCc3ccccc3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C21H27N3O5S/c1-15(2)12-19(21(25)23-26)24-11-10-22-18-13-17(8-9-20(18)30(24,27)28)29-14-16-6-4-3-5-7-16/h3-9,13,15,19,22,26H,10-12,14H2,1-2H3,(H,23,25)/t19-/m1/s1 JRXNWTIRACLYGX-LJQANCHMSA-N 50127481 2-(7-Benzyloxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-4-methyl-pentanoic acid hydroxyamide::CHEMBL431926 Disintegrin and metalloproteinase domain-containing protein 17 177 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127481&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10252311 104019372 CHEMBL431926 ZINC13518153 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122180 C[C@@H](N1CCNc2cc(OCc3cc(Cl)cc(Cl)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C18H19Cl2N3O5S/c1-11(18(24)22-25)23-5-4-21-16-9-15(2-3-17(16)29(23,26)27)28-10-12-6-13(19)8-14(20)7-12/h2-3,6-9,11,21,25H,4-5,10H2,1H3,(H,22,24)/t11-/m1/s1 WIOHNTSOYPKJIX-LLVKDONJSA-N 50127483 2-[7-(3,5-Dichloro-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL52893 Disintegrin and metalloproteinase domain-containing protein 17 940 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127483&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10895808 104019374 CHEMBL52893 ZINC13518136 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122224 COc1cc(COc2ccc3c(NCCN([C@H](CCCCNS(C)(=O)=O)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C24H34N4O9S2/c1-35-19-12-17(13-20(14-19)36-2)16-37-18-7-8-23-21(15-18)25-10-11-28(39(23,33)34)22(24(29)27-30)6-4-5-9-26-38(3,31)32/h7-8,12-15,22,25-26,30H,4-6,9-11,16H2,1-3H3,(H,27,29)/t22-/m1/s1 DNEUAPIVDBXPFN-JOCHJYFZSA-N 50127472 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-6-methanesulfonylamino-hexanoic acid hydroxyamide::CHEMBL416306 Disintegrin and metalloproteinase domain-containing protein 17 1900 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9960075 104019363 CHEMBL416306 ZINC29483126 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122225 CCOc1cc(COc2ccc3c(NCCN([C@H](C(C)C)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C24H33N3O7S/c1-5-32-19-11-17(12-20(13-19)33-6-2)15-34-18-7-8-22-21(14-18)25-9-10-27(35(22,30)31)23(16(3)4)24(28)26-29/h7-8,11-14,16,23,25,29H,5-6,9-10,15H2,1-4H3,(H,26,28)/t23-/m1/s1 WJPORLWHPJGLSC-HSZRJFAPSA-N 50127455 2-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-3-methyl-butyramide::CHEMBL54292 Disintegrin and metalloproteinase domain-containing protein 17 8200 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127455&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11027584 104019346 CHEMBL54292 ZINC13518162 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122227 C[C@@H](N1CCNc2cc(Oc3ccc(cc3)[N+]([O-])=O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C17H18N4O7S/c1-11(17(22)19-23)20-9-8-18-15-10-14(6-7-16(15)29(20,26)27)28-13-4-2-12(3-5-13)21(24)25/h2-7,10-11,18,23H,8-9H2,1H3,(H,19,22)/t11-/m1/s1 KQVRGIRNMDCIEB-LLVKDONJSA-N 50127454 CHEMBL301303::N-Hydroxy-2-[7-(4-nitro-phenoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127454&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10884337 104019345 CHEMBL301303 ZINC13518201 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122229 COc1cc(COc2ccc3c(NCCN([C@H](CC(C)C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C23H31N3O7S/c1-15(2)9-21(23(27)25-28)26-8-7-24-20-13-17(5-6-22(20)34(26,29)30)33-14-16-10-18(31-3)12-19(11-16)32-4/h5-6,10-13,15,21,24,28H,7-9,14H2,1-4H3,(H,25,27)/t21-/m1/s1 NSLCGVDBXCHQFK-OAQYLSRUSA-N 50127471 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-methyl-pentanoic acid hydroxyamide::CHEMBL293074 Disintegrin and metalloproteinase domain-containing protein 17 5400 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127471&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11060081 104019362 CHEMBL293074 ZINC13518156 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122248 C[C@@H](N1CCNc2cc(Oc3cccc(c3)[N+]([O-])=O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C17H18N4O7S/c1-11(17(22)19-23)20-8-7-18-15-10-14(5-6-16(15)29(20,26)27)28-13-4-2-3-12(9-13)21(24)25/h2-6,9-11,18,23H,7-8H2,1H3,(H,19,22)/t11-/m1/s1 HEHZCMROVKSJTK-LLVKDONJSA-N 50127460 CHEMBL52659::N-Hydroxy-2-[7-(3-nitro-phenoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 129 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127460&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11732585 104019351 CHEMBL52659 ZINC13518198 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122250 CC(C)[C@@H](N1CCNc2cc(OCc3nc(C)c(C)s3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C19H26N4O5S2/c1-11(2)18(19(24)22-25)23-8-7-20-15-9-14(5-6-16(15)30(23,26)27)28-10-17-21-12(3)13(4)29-17/h5-6,9,11,18,20,25H,7-8,10H2,1-4H3,(H,22,24)/t18-/m1/s1 RNWFVTPNHGOAMY-GOSISDBHSA-N 50127459 2-[7-(4,5-Dimethyl-thiazol-2-ylmethoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-3-methyl-butyramide::CHEMBL53055 Disintegrin and metalloproteinase domain-containing protein 17 24500 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127459&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11080936 104019350 CHEMBL53055 ZINC13518165 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122252 CCOc1cc(COc2ccc3c(NCCN([C@H](CCC(=O)OC)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C25H33N3O9S/c1-4-35-19-12-17(13-20(14-19)36-5-2)16-37-18-6-8-23-21(15-18)26-10-11-28(38(23,32)33)22(25(30)27-31)7-9-24(29)34-3/h6,8,12-15,22,26,31H,4-5,7,9-11,16H2,1-3H3,(H,27,30)/t22-/m1/s1 HTAGYDAMQNRLDD-JOCHJYFZSA-N 50127453 4-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-hydroxycarbamoyl-butyric acid methyl ester::CHEMBL53250 Disintegrin and metalloproteinase domain-containing protein 17 242 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127453&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11092861 104019344 CHEMBL53250 ZINC29488588 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50120114 COc1ccc(cc1)P(=O)(OC)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C18H21N2O5P/c1-24-15-7-9-16(10-8-15)26(23,25-2)20-12-14-6-4-3-5-13(14)11-17(20)18(21)19-22/h3-10,17,22H,11-12H2,1-2H3,(H,19,21) RTKNMWBYPISZDZ-UHFFFAOYSA-N 50109630 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid methyl ester::CHEMBL170315 Disintegrin and metalloproteinase domain-containing protein 17 <1000 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109630&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383789 104004570 CHEMBL170315 ZINC28005890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50120121 CCOP(=O)(N1Cc2ccccc2C[C@@H]1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H23N2O5P/c1-3-26-27(24,17-10-8-16(25-2)9-11-17)21-13-15-7-5-4-6-14(15)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22)/t18-,27?/m1/s1 RBLCSCFFNCADJO-XZATXCMXSA-N 50171860 ((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL363424 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171860&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399042 104058052 CHEMBL363424 ZINC13438427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50120813 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2c(C)cncc2C)cc1)C(=O)NO InChI=1S/C22H27N3O4/c1-14-11-23-12-15(2)19(14)13-29-18-7-5-17(6-8-18)22(4)9-10-25(21(22)27)16(3)20(26)24-28/h5-8,11-12,16,28H,9-10,13H2,1-4H3,(H,24,26)/t16-,22+/m1/s1 YBFNSQBHQFSVAT-ZHRRBRCNSA-N 50120684 2-{3-[4-(3,5-Dimethyl-pyridin-4-ylmethoxy)-phenyl]-3-methyl-2-oxo-pyrrolidin-1-yl}-N-hydroxy-propionamide::CHEMBL436071 Disintegrin and metalloproteinase domain-containing protein 17 8.10 ChEMBL 10.1021/jm0255670 10.7270/Q2XP7497 12408705 Duan, JJ; Chen, L; Wasserman, ZR; Lu, Z; Liu, RQ; Covington, MB; Qian, M; Hardman, KD; Magolda, RL; Newton, RC; Christ, DD; Wexler, RR; Decicco, CP Bristol-Myers Squibb Co. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120684&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363884 104013726 CHEMBL436071 ZINC27555483 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50126238 CCC1CC(=O)N(c2ccc(Oc3ccccc3)cc2)C11C(=O)NC(=O)NC1=O InChI=1S/C21H19N3O5/c1-2-13-12-17(25)24(21(13)18(26)22-20(28)23-19(21)27)14-8-10-16(11-9-14)29-15-6-4-3-5-7-15/h3-11,13H,2,12H2,1H3,(H2,22,23,26,27,28) QBWALRVIJDSECI-UHFFFAOYSA-N 50160852 4-ethyl-1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone::CHEMBL361527 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.12.016 10.7270/Q2F47NN2 15686921 Kim, SH; Pudzianowski, AT; Leavitt, KJ; Barbosa, J; McDonnell, PA; Metzler, WJ; Rankin, BM; Liu, R; Vaccaro, W; Pitts, W Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160852&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11257884 104047312 CHEMBL361527 ZINC28128721 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50124933 CCCCCC[C@@H](C(=O)NO)S(=O)c1ccc(OCC#CC)cc1 InChI=1S/C18H25NO4S/c1-3-5-7-8-9-17(18(20)19-21)24(22)16-12-10-15(11-13-16)23-14-6-4-2/h10-13,17,21H,3,5,7-9,14H2,1-2H3,(H,19,20)/t17-,24?/m0/s1 RBRFAUFMZOIMMS-KEJDIYNNSA-N 50411313 CHEMBL2096853 Disintegrin and metalloproteinase domain-containing protein 17 4.0 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411313&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9884836 163360337 CHEMBL2096853 ZINC13585936 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122988 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C18H20N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15+,16+,17+/m0/s1 WLWNRAWQDZRXMB-YLFCFFPRSA-N 50131385 (2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::(2R,3R,4R,5S)-N,3,4,5-tetrahydroxy-1-(4-phenoxyphenylsulfonyl)piperidine-2-carboxamide::CHEMBL61193 Disintegrin and metalloproteinase domain-containing protein 17 350 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131385&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910222 104022557 CHEMBL61193 6514 ZINC13537266 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122990 COc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO InChI=1S/C13H18N2O8S/c1-23-7-2-4-8(5-3-7)24(21,22)15-6-9(16)11(17)12(18)10(15)13(19)14-20/h2-5,9-12,16-18,20H,6H2,1H3,(H,14,19)/t9-,10-,11-,12-/m1/s1 SSQXFNKOLMHXPO-DDHJBXDOSA-N 50143731 (2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL57644 Disintegrin and metalloproteinase domain-containing protein 17 450 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143731&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11360440 104032891 CHEMBL57644 ZINC13560272 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122991 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C18H20N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15-,16-,17-/m1/s1 WLWNRAWQDZRXMB-QBPKDAKJSA-N 50143729 (2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-phenoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL56837 Disintegrin and metalloproteinase domain-containing protein 17 340 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143729&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9802436 104032889 CHEMBL56837 ZINC03941984 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122994 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H22N2O8S/c22-15-10-21(16(19(25)20-26)18(24)17(15)23)30(27,28)14-8-6-13(7-9-14)29-11-12-4-2-1-3-5-12/h1-9,15-18,22-24,26H,10-11H2,(H,20,25)/t15-,16-,17-,18-/m1/s1 LQZDEWIIFWHTLX-BRSBDYLESA-N 50143732 (2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL58577 Disintegrin and metalloproteinase domain-containing protein 17 84 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143732&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11374008 104032892 CHEMBL58577 ZINC13560274 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122996 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C18H20N2O7S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)28(26,27)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15-,16-,17-/m1/s1 YFXAPTTTXDTWSV-QBPKDAKJSA-N 50143730 (2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL60536 Disintegrin and metalloproteinase domain-containing protein 17 21000 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143730&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11407165 104032890 CHEMBL60536 ZINC13560273 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50122997 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO InChI=1S/C16H20N2O8S/c1-2-3-8-26-10-4-6-11(7-5-10)27(24,25)18-9-12(19)14(20)15(21)13(18)16(22)17-23/h4-7,12-15,19-21,23H,8-9H2,1H3,(H,17,22)/t12-,13-,14-,15-/m1/s1 WSWMIGCNSWBCNT-KBUPBQIOSA-N 50141577 (2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL43087 Disintegrin and metalloproteinase domain-containing protein 17 0.530000 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11246575 104031036 CHEMBL43087 ZINC13560275 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130283 COC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C17H21N3O7S/c1-3-4-11-27-13-5-7-14(8-6-13)28(24,25)20-10-9-19(17(22)26-2)12-15(20)16(21)18-23/h5-8,15,23H,9-12H2,1-2H3,(H,18,21) XRGWUGBXRHDGDG-UHFFFAOYSA-N 50171540 4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-piperazine-1-carboxylic acid methyl ester::CHEMBL372908 Disintegrin and metalloproteinase domain-containing protein 17 9.0 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171540&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9887831 104057737 CHEMBL372908 ZINC28526807 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130284 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSCC1C(=O)NO InChI=1S/C15H18N2O5S2/c1-2-3-9-22-12-4-6-13(7-5-12)24(20,21)17-8-10-23-11-14(17)15(18)16-19/h4-7,14,19H,8-11H2,1H3,(H,16,18) KQEHQRICYJKJLB-UHFFFAOYSA-N 50171539 4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL370129 Disintegrin and metalloproteinase domain-containing protein 17 3.0 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171539&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9842332 104057736 CHEMBL370129 ZINC28525999 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130285 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)S(C)(=O)=O InChI=1S/C16H21N3O7S2/c1-3-4-11-26-13-5-7-14(8-6-13)28(24,25)19-10-9-18(27(2,22)23)12-15(19)16(20)17-21/h5-8,15,21H,9-12H2,1-2H3,(H,17,20) VRUQYJXYEALKCT-UHFFFAOYSA-N 50171536 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfonyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL194237 Disintegrin and metalloproteinase domain-containing protein 17 7.0 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171536&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9867411 104057733 CHEMBL194237 ZINC28526809 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130286 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCOCC1C(=O)NO InChI=1S/C15H18N2O6S/c1-2-3-9-23-12-4-6-13(7-5-12)24(20,21)17-8-10-22-11-14(17)15(18)16-19/h4-7,14,19H,8-11H2,1H3,(H,16,18) SEOIKBYFTLCBTF-UHFFFAOYSA-N 50171538 4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-carboxylic acid hydroxyamide::CHEMBL196092 Disintegrin and metalloproteinase domain-containing protein 17 5.0 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171538&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9819974 104057735 CHEMBL196092 ZINC28525997 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130288 CCN(CC)C(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C20H28N4O6S/c1-4-7-14-30-16-8-10-17(11-9-16)31(28,29)24-13-12-23(15-18(24)19(25)21-27)20(26)22(5-2)6-3/h8-11,18,27H,5-6,12-15H2,1-3H3,(H,21,25) SQODILRODCBOCF-UHFFFAOYSA-N 50171542 4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-diethylamide 3-hydroxyamide::CHEMBL370825 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171542&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868490 104057739 CHEMBL370825 ZINC28528953 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130289 CCCCC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C20H27N3O6S/c1-3-5-7-19(24)22-12-13-23(18(15-22)20(25)21-26)30(27,28)17-10-8-16(9-11-17)29-14-6-4-2/h8-11,18,26H,3,5,7,12-15H2,1-2H3,(H,21,25) CYIOQNVVHKTYRH-UHFFFAOYSA-N 50171544 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL198100 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171544&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44404761 104057741 CHEMBL198100 ZINC28528042 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130291 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC2(CCCC2)C1C(=O)NO InChI=1S/C19H24N2O5S2/c1-2-3-13-26-15-6-8-16(9-7-15)28(24,25)21-12-14-27-19(10-4-5-11-19)17(21)18(22)20-23/h6-9,17,23H,4-5,10-14H2,1H3,(H,20,22) LMASIGSKSCEZDY-UHFFFAOYSA-N 50171541 9-(4-But-2-ynyloxy-benzenesulfonyl)-6-thia-9-aza-spiro[4.5]decane-10-carboxylic acid hydroxyamide::CHEMBL434187 Disintegrin and metalloproteinase domain-containing protein 17 43 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171541&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9954117 104057738 CHEMBL434187 ZINC28527681 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130341 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)C1C(=O)NO InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,10-12H2,1-3H3,(H,18,20) CVZIHNYAZLXRRS-UHFFFAOYSA-N 50171543 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-2,2-dimethyl-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL382975 Disintegrin and metalloproteinase domain-containing protein 17 8.0 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171543&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search IH6 1ZXC 6323382 104057740 CHEMBL382975 ZINC28527693 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130342 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(C)=O InChI=1S/C17H21N3O6S/c1-3-4-11-26-14-5-7-15(8-6-14)27(24,25)20-10-9-19(13(2)21)12-16(20)17(22)18-23/h5-8,16,23H,9-12H2,1-2H3,(H,18,22) VJCSPSPTFYXXJB-UHFFFAOYSA-N 50171535 4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL195948 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171535&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9908681 104057732 CHEMBL195948 ZINC28526076 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130343 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1cccs1 InChI=1S/C20H21N3O6S2/c1-2-3-12-29-15-6-8-16(9-7-15)31(27,28)23-11-10-22(14-17(23)19(24)21-26)20(25)18-5-4-13-30-18/h4-9,13,17,26H,10-12,14H2,1H3,(H,21,24) QFTWPDUNHCKGKX-UHFFFAOYSA-N 50171537 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2-carbonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL381224 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171537&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9912235 104057734 CHEMBL381224 ZINC28528216 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130344 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(Cc2cccnc2)CC1C(=O)NO InChI=1S/C21H24N4O5S/c1-2-3-13-30-18-6-8-19(9-7-18)31(28,29)25-12-11-24(16-20(25)21(26)23-27)15-17-5-4-10-22-14-17/h4-10,14,20,27H,11-13,15-16H2,1H3,(H,23,26) YCIYENASUWAOBH-UHFFFAOYSA-N 50171545 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pyridin-3-ylmethyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL194627 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171545&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9955127 104057742 CHEMBL194627 ZINC28526223 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50130349 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCNCC1C(=O)NO InChI=1S/C15H19N3O5S/c1-2-3-10-23-12-4-6-13(7-5-12)24(21,22)18-9-8-16-11-14(18)15(19)17-20/h4-7,14,16,20H,8-11H2,1H3,(H,17,19) ZTVJLUOPMWIKSV-UHFFFAOYSA-N 50171534 1-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL436324 Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171534&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9798637 104057731 CHEMBL436324 ZINC28525784 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50137081 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)Cc1ccccc1)C(=O)NO InChI=1S/C24H28N2O7S2/c1-2-3-17-33-21-9-11-22(12-10-21)34(29,30)19-24(23(27)25-28)13-15-26(16-14-24)35(31,32)18-20-7-5-4-6-8-20/h4-12,28H,13-19H2,1H3,(H,25,27) BXOTYZMFPUKYAU-UHFFFAOYSA-N 50187792 1-(benzylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL210133 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187792 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187792&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413992 104071618 CHEMBL210133 ZINC34801898 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50137396 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1cccs1)C(=O)NO InChI=1S/C22H24N2O6S2/c1-2-3-14-30-17-6-8-18(9-7-17)32(28,29)16-22(21(26)23-27)10-12-24(13-11-22)20(25)19-5-4-15-31-19/h4-9,15,27H,10-14,16H2,1H3,(H,23,26) WPYFTDWGMAINBU-UHFFFAOYSA-N 50187786 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(thiophene-2-carbonyl)piperidine-4-carboxamide::CHEMBL211770 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187786&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513795 104071612 CHEMBL211770 ZINC34801900 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50139802 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1nc(C)sc1C)C(=O)NO InChI=1S/C22H27N3O7S3/c1-4-5-14-32-18-6-8-19(9-7-18)34(28,29)15-22(21(26)24-27)10-12-25(13-11-22)35(30,31)20-16(2)33-17(3)23-20/h6-9,27H,10-15H2,1-3H3,(H,24,26) LNLWALQGRPVSTA-UHFFFAOYSA-N 50197214 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(2,5-dimethylthiazol-4-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL391676 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429896 104078644 CHEMBL391676 ZINC28816902 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50139803 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)(C)C)C(=O)NO InChI=1S/C21H30N2O7S2/c1-5-6-15-30-17-7-9-18(10-8-17)31(26,27)16-21(19(24)22-25)11-13-23(14-12-21)32(28,29)20(2,3)4/h7-10,25H,11-16H2,1-4H3,(H,22,24) ZYKVSIDVBIFMGD-UHFFFAOYSA-N 50197234 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(tert-butylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL233932 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197234 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197234&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429878 104078664 CHEMBL233932 ZINC28816863 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50139805 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1cc(Cl)sc1Cl)C(=O)NO InChI=1S/C21H22Cl2N2O7S3/c1-2-3-12-32-15-4-6-16(7-5-15)34(28,29)14-21(20(26)24-27)8-10-25(11-9-21)35(30,31)17-13-18(22)33-19(17)23/h4-7,13,27H,8-12,14H2,1H3,(H,24,26) PRHFUFABVIQNBK-UHFFFAOYSA-N 50197228 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(2,5-dichlorothiophen-3-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234776 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197228&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429894 104078658 CHEMBL234776 ZINC28816900 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50139806 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1c(Cl)cncc1Cl)C(=O)NO InChI=1S/C23H23Cl2N3O6S/c1-2-3-12-34-16-4-6-17(7-5-16)35(32,33)15-23(22(30)27-31)8-10-28(11-9-23)21(29)20-18(24)13-26-14-19(20)25/h4-7,13-14,31H,8-12,15H2,1H3,(H,27,30) IDHBZDJZPPEMGC-UHFFFAOYSA-N 50197220 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5-dichloroisonicotinoyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL391881 Disintegrin and metalloproteinase domain-containing protein 17 1.7 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197220&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429905 104078650 CHEMBL391881 ZINC28816914 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50139810 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)c1nc2ccccc2n1C)C(=O)NO InChI=1S/C25H28N4O5S/c1-3-4-17-34-19-9-11-20(12-10-19)35(32,33)18-25(23(30)27-31)13-15-29(16-14-25)24-26-21-7-5-6-8-22(21)28(24)2/h5-12,31H,13-18H2,1-2H3,(H,27,30) GFRCZBUEHADXTC-UHFFFAOYSA-N 50197221 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(1-methyl-1H-benzo[d]imidazol-2-yl)piperidine-4-carboxamide::CHEMBL234566 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197221&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429890 104078651 CHEMBL234566 ZINC28816890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50139814 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1c(C)nn(C)c1C)C(=O)NO InChI=1S/C23H30N4O7S2/c1-5-6-15-34-19-7-9-20(10-8-19)35(30,31)16-23(22(28)25-29)11-13-27(14-12-23)36(32,33)21-17(2)24-26(4)18(21)3/h7-10,29H,11-16H2,1-4H3,(H,25,28) UHWQCCAGEXNQTH-UHFFFAOYSA-N 50197212 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(1,3,5-trimethyl-1H-pyrazol-4-ylsulfonyl)piperidine-4-carboxamide::CHEMBL393750 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429891 104078642 CHEMBL393750 ZINC28816894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50139815 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)CC1CCCCC1)C(=O)NO InChI=1S/C24H34N2O7S2/c1-2-3-17-33-21-9-11-22(12-10-21)34(29,30)19-24(23(27)25-28)13-15-26(16-14-24)35(31,32)18-20-7-5-4-6-8-20/h9-12,20,28H,4-8,13-19H2,1H3,(H,25,27) DKLKUPISRVEUAG-UHFFFAOYSA-N 50197215 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyclohexylmethylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234143 Disintegrin and metalloproteinase domain-containing protein 17 <1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429881 104078645 CHEMBL234143 ZINC28816869 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145904 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc(cc1)C#N)C(=O)NO)C(C)(C)C InChI=1S/C22H32N4O4S/c1-13(2)11-16(19(27)25-18(21(29)24-6)22(3,4)5)17(20(28)26-30)31-15-9-7-14(12-23)8-10-15/h7-10,13,16-18,30H,11H2,1-6H3,(H,24,29)(H,25,27)(H,26,28)/t16-,17+,18-/m1/s1 LDFJGSZPKVRXOC-FGTMMUONSA-N 50082939 (2S,3S)-2-(4-Cyano-phenylsulfanyl)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL342069 Disintegrin and metalloproteinase domain-containing protein 17 0.63 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082939&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10837188 103982674 CHEMBL342069 ZINC13802333 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145905 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1c(cc(cc1C(C)C)C(C)C)C(C)C)C(=O)NO)C(C)(C)C InChI=1S/C30H52N4O6S/c1-16(2)13-23(27(35)32-26(29(37)31-12)30(9,10)11)24(28(36)33-38)34-41(39,40)25-21(18(5)6)14-20(17(3)4)15-22(25)19(7)8/h14-19,23-24,26,34,38H,13H2,1-12H3,(H,31,37)(H,32,35)(H,33,36)/t23-,24+,26-/m1/s1 XCJWLVBPPGUMMI-RMTZWNOUSA-N 50082943 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2,4,6-triisopropyl-benzenesulfonylamino)-succinamide::CHEMBL144074 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082943&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363603 103982678 CHEMBL144074 ZINC27552581 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145906 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OC)C(=O)NO)C(C)(C)C InChI=1S/C16H31N3O5/c1-9(2)8-10(11(24-7)14(21)19-23)13(20)18-12(15(22)17-6)16(3,4)5/h9-12,23H,8H2,1-7H3,(H,17,22)(H,18,20)(H,19,21)/t10-,11+,12-/m1/s1 AJIRKSAIZYDGMB-GRYCIOLGSA-N 50082940 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-methoxy-succinamide::CHEMBL357195 Disintegrin and metalloproteinase domain-containing protein 17 5000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082940&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9928154 103982675 CHEMBL357195 ZINC13802398 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145907 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N1CCCC1)C(=O)NO)C(C)(C)C InChI=1S/C19H36N4O4/c1-12(2)11-13(14(17(25)22-27)23-9-7-8-10-23)16(24)21-15(18(26)20-6)19(3,4)5/h12-15,27H,7-11H2,1-6H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-/m1/s1 YHQYCXXDVJZMED-QLFBSQMISA-N 50082941 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-pyrrolidin-1-yl-succinamide::CHEMBL144857 Disintegrin and metalloproteinase domain-containing protein 17 2.8 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082941&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10572102 103982676 CHEMBL144857 ZINC13802386 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145908 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)\C=C\c1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C23H36N4O6S/c1-15(2)14-17(20(28)25-19(22(30)24-6)23(3,4)5)18(21(29)26-31)27-34(32,33)13-12-16-10-8-7-9-11-16/h7-13,15,17-19,27,31H,14H2,1-6H3,(H,24,30)(H,25,28)(H,26,29)/b13-12+/t17-,18+,19-/m1/s1 PBSIODYTWGDTMB-MCXDLHDFSA-N 50082942 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-((E)-2-phenyl-ethenesulfonylamino)-succinamide::CHEMBL144363 Disintegrin and metalloproteinase domain-containing protein 17 0.54 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10994673 103982677 CHEMBL144363 ZINC13802370 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145909 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1cccc(c1)C(C)(C)C#N)C(=O)NO)C(C)(C)C InChI=1S/C25H38N4O4S/c1-15(2)12-18(21(30)28-20(23(32)27-8)24(3,4)5)19(22(31)29-33)34-17-11-9-10-16(13-17)25(6,7)14-26/h9-11,13,15,18-20,33H,12H2,1-8H3,(H,27,32)(H,28,30)(H,29,31)/t18-,19+,20-/m1/s1 QDIXPUMJVOLKDW-HSALFYBXSA-N 50082944 (2S,3S)-2-[3-(Cyano-dimethyl-methyl)-phenylsulfanyl]-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL355900 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082944&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10577036 103982679 CHEMBL355900 ZINC13802340 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145910 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O6S/c1-14(2)13-16(21(30)27-20(23(32)25-6)24(3,4)5)19(22(31)28-33)29-36(34,35)17-11-7-9-15-10-8-12-26-18(15)17/h7-12,14,16,19-20,29,33H,13H2,1-6H3,(H,25,32)(H,27,30)(H,28,31)/t16-,19+,20-/m1/s1 MDENDLKFAFTBOF-LSTHTHJFSA-N 50082945 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinoline-8-sulfonylamino)-succinamide::CHEMBL144843 Disintegrin and metalloproteinase domain-containing protein 17 4.2 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082945&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10602071 103982680 CHEMBL144843 ZINC13802362 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145911 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cc2c(cc1Br)nc(C)[nH]c2=O)C(=O)NO)C(C)(C)C InChI=1S/C25H36BrN5O6/c1-12(2)8-16(22(33)30-20(24(35)27-7)25(4,5)6)19(23(34)31-36)37-11-14-9-15-18(10-17(14)26)28-13(3)29-21(15)32/h9-10,12,16,19-20,36H,8,11H2,1-7H3,(H,27,35)(H,30,33)(H,31,34)(H,28,29,32)/t16-,19+,20-/m1/s1 VMGWEPZCVOOZNU-LSTHTHJFSA-N 50082946 (2R,3S)-2-(7-Bromo-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethoxy)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL357203 Disintegrin and metalloproteinase domain-containing protein 17 0.33 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082946&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10531330 103982681 CHEMBL357203 ZINC27553633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145913 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)\C=C\c1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C23H36N4O6S/c1-15(2)14-17(20(28)25-19(22(30)24-6)23(3,4)5)18(21(29)26-31)27-34(32,33)13-12-16-10-8-7-9-11-16/h7-13,15,17-19,27,31H,14H2,1-6H3,(H,24,30)(H,25,28)(H,26,29)/b13-12+/t17-,18+,19-/m1/s1 PBSIODYTWGDTMB-MCXDLHDFSA-N 50082942 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-((E)-2-phenyl-ethenesulfonylamino)-succinamide::CHEMBL144363 Disintegrin and metalloproteinase domain-containing protein 17 770 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10994673 103982677 CHEMBL144363 ZINC13802370 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145914 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(Br)cc1)C(=O)NO)C(C)(C)C InChI=1S/C21H33BrN4O6S/c1-12(2)11-15(18(27)24-17(20(29)23-6)21(3,4)5)16(19(28)25-30)26-33(31,32)14-9-7-13(22)8-10-14/h7-10,12,15-17,26,30H,11H2,1-6H3,(H,23,29)(H,24,27)(H,25,28)/t15-,16+,17-/m1/s1 UIJLTUOXWZPTFC-IXDOHACOSA-N 50082947 (2R,3S)-2-(4-Bromo-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL358129 Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363331 103982682 CHEMBL358129 ZINC27550633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145916 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cc2ccccc2n(C)c1=O)C(=O)NO)C(C)(C)C InChI=1S/C26H38N4O6/c1-15(2)12-18(22(31)28-21(24(33)27-6)26(3,4)5)20(23(32)29-35)36-14-17-13-16-10-8-9-11-19(16)30(7)25(17)34/h8-11,13,15,18,20-21,35H,12,14H2,1-7H3,(H,27,33)(H,28,31)(H,29,32)/t18-,20+,21-/m1/s1 NLDPPTDLJLPBHD-HLAWJBBLSA-N 50082948 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2-dihydro-quinolin-3-ylmethoxy)-succinamide::CHEMBL144101 Disintegrin and metalloproteinase domain-containing protein 17 2350 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082948&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10696802 103982683 CHEMBL144101 ZINC13802395 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145917 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)CCc1ccncc1)C(=O)NO)C(C)(C)C InChI=1S/C22H37N5O6S/c1-14(2)13-16(19(28)25-18(21(30)23-6)22(3,4)5)17(20(29)26-31)27-34(32,33)12-9-15-7-10-24-11-8-15/h7-8,10-11,14,16-18,27,31H,9,12-13H2,1-6H3,(H,23,30)(H,25,28)(H,26,29)/t16-,17+,18-/m1/s1 KWTUEDAYOTUMEG-FGTMMUONSA-N 50082952 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-pyridin-4-yl-ethanesulfonylamino)-succinamide::CHEMBL144780 Disintegrin and metalloproteinase domain-containing protein 17 1.3 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082952&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10839079 103982687 CHEMBL144780 ZINC13802368 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145918 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)CC(=O)NO)C(C)(C)C InChI=1S/C15H29N3O4/c1-9(2)7-10(8-11(19)18-22)13(20)17-12(14(21)16-6)15(3,4)5/h9-10,12,22H,7-8H2,1-6H3,(H,16,21)(H,17,20)(H,18,19)/t10-,12-/m1/s1 QRXOZHSEEGNRFC-ZYHUDNBSSA-N 50063920 (R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-succinamide::(R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::CHEMBL16520::Ro-31-9790 Disintegrin and metalloproteinase domain-containing protein 17 >50000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063920&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9904965 103959092 CHEMBL16520 ZINC01534591 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145919 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cccc2nccnc12)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O5/c1-14(2)12-16(21(30)28-20(23(32)25-6)24(3,4)5)19(22(31)29-33)34-13-15-8-7-9-17-18(15)27-11-10-26-17/h7-11,14,16,19-20,33H,12-13H2,1-6H3,(H,25,32)(H,28,30)(H,29,31)/t16-,19+,20-/m1/s1 VQTLMFHSJXBYBD-LSTHTHJFSA-N 50082950 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinoxalin-5-ylmethoxy)-succinamide::CHEMBL148395 Disintegrin and metalloproteinase domain-containing protein 17 1.1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082950&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10719273 103982685 CHEMBL148395 ZINC03821617 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145920 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2NC(=O)Cc2c1)C(=O)NO)C(C)(C)C InChI=1S/C23H35N5O7S/c1-12(2)9-15(20(30)26-19(22(32)24-6)23(3,4)5)18(21(31)27-33)28-36(34,35)14-7-8-16-13(10-14)11-17(29)25-16/h7-8,10,12,15,18-19,28,33H,9,11H2,1-6H3,(H,24,32)(H,25,29)(H,26,30)(H,27,31)/t15-,18+,19-/m1/s1 QKZJSMFYXFCVSP-AYOQOUSVSA-N 50082951 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-oxo-2,3-dihydro-1H-indole-5-sulfonylamino)-succinamide::CHEMBL144206 Disintegrin and metalloproteinase domain-containing protein 17 1500 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082951&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10673661 103982686 CHEMBL144206 ZINC27552038 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145921 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H37N3O5/c1-16(2)13-20(23(30)28-22(25(32)27-6)26(3,4)5)21(24(31)29-33)34-15-17-11-12-18-9-7-8-10-19(18)14-17/h7-12,14,16,20-22,33H,13,15H2,1-6H3,(H,27,32)(H,28,30)(H,29,31)/t20-,21+,22-/m1/s1 QWPOEQKVJCDSNI-BHIFYINESA-N 50082949 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalen-2-ylmethoxy)-succinamide::CHEMBL344312 Disintegrin and metalloproteinase domain-containing protein 17 0.6 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082949&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10504593 103982684 CHEMBL344312 ZINC13802404 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145923 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N(C)S(=O)(=O)c1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O6S/c1-15(2)14-17(22(31)28-21(24(33)26-6)25(3,4)5)20(23(32)29-34)30(7)37(35,36)18-12-8-10-16-11-9-13-27-19(16)18/h8-13,15,17,20-21,34H,14H2,1-7H3,(H,26,33)(H,28,31)(H,29,32)/t17-,20+,21-/m1/s1 SCRXVDGCFAHYTL-JRGCBEDISA-N 50082958 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[methyl-(quinoline-8-sulfonyl)-amino]-succinamide::CHEMBL342732 Disintegrin and metalloproteinase domain-containing protein 17 4.4 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082958&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10840060 103982693 CHEMBL342732 ZINC27548899 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145925 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2c1nc[nH]c2=O)C(=O)NO)C(C)(C)C InChI=1S/C23H34N6O7S/c1-12(2)10-14(20(31)27-18(22(33)24-6)23(3,4)5)17(21(32)28-34)29-37(35,36)15-9-7-8-13-16(15)25-11-26-19(13)30/h7-9,11-12,14,17-18,29,34H,10H2,1-6H3,(H,24,33)(H,27,31)(H,28,32)(H,25,26,30)/t14-,17+,18-/m1/s1 WOGYYBSXXNJSRS-FHLIZLRMSA-N 50082956 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(4-oxo-3,4-dihydro-quinazoline-8-sulfonylamino)-succinamide::CHEMBL148048 Disintegrin and metalloproteinase domain-containing protein 17 3.4 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10792503 103982691 CHEMBL148048 ZINC27553845 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145926 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(F)cc1Cl)C(=O)NO)C(C)(C)C InChI=1S/C21H32ClFN4O6S/c1-11(2)9-13(18(28)25-17(20(30)24-6)21(3,4)5)16(19(29)26-31)27-34(32,33)15-8-7-12(23)10-14(15)22/h7-8,10-11,13,16-17,27,31H,9H2,1-6H3,(H,24,30)(H,25,28)(H,26,29)/t13-,16+,17-/m1/s1 SEMMQAJGPSCCIH-XOKHGSTOSA-N 50082955 (2R,3S)-2-(2-Chloro-4-fluoro-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL146831 Disintegrin and metalloproteinase domain-containing protein 17 9.7 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082955&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10530046 103982690 CHEMBL146831 ZINC13802350 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145927 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2ncccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O6S/c1-14(2)12-17(21(30)27-20(23(32)25-6)24(3,4)5)19(22(31)28-33)29-36(34,35)16-9-10-18-15(13-16)8-7-11-26-18/h7-11,13-14,17,19-20,29,33H,12H2,1-6H3,(H,25,32)(H,27,30)(H,28,31)/t17-,19+,20-/m1/s1 JIZLXLHASQJXJD-YZGWKJHDSA-N 50082957 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinoline-6-sulfonylamino)-succinamide::CHEMBL344759 Disintegrin and metalloproteinase domain-containing protein 17 440.0 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10602072 103982692 CHEMBL344759 ZINC13802367 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145928 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(=O)c1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C22H34N4O5/c1-13(2)12-15(19(28)25-17(21(30)23-6)22(3,4)5)16(20(29)26-31)24-18(27)14-10-8-7-9-11-14/h7-11,13,15-17,31H,12H2,1-6H3,(H,23,30)(H,24,27)(H,25,28)(H,26,29)/t15-,16+,17-/m1/s1 FLACUUZPSKFFIA-IXDOHACOSA-N 50082954 (2R,3S)-2-Benzoylamino-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL358770 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082954&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10622714 103982689 CHEMBL358770 ZINC13802380 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145929 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2NC(=O)Cc2c1)C(=O)NO)C(C)(C)C InChI=1S/C23H35N5O7S/c1-12(2)9-15(20(30)26-19(22(32)24-6)23(3,4)5)18(21(31)27-33)28-36(34,35)14-7-8-16-13(10-14)11-17(29)25-16/h7-8,10,12,15,18-19,28,33H,9,11H2,1-6H3,(H,24,32)(H,25,29)(H,26,30)(H,27,31)/t15-,18+,19-/m1/s1 QKZJSMFYXFCVSP-AYOQOUSVSA-N 50082951 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-oxo-2,3-dihydro-1H-indole-5-sulfonylamino)-succinamide::CHEMBL144206 Disintegrin and metalloproteinase domain-containing protein 17 2.8 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082951&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10673661 103982686 CHEMBL144206 ZINC27552038 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145930 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N(C)S(=O)(=O)c1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O6S/c1-15(2)14-17(22(31)28-21(24(33)26-6)25(3,4)5)20(23(32)29-34)30(7)37(35,36)18-12-8-10-16-11-9-13-27-19(16)18/h8-13,15,17,20-21,34H,14H2,1-7H3,(H,26,33)(H,28,31)(H,29,32)/t17-,20+,21-/m1/s1 SCRXVDGCFAHYTL-JRGCBEDISA-N 50082958 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[methyl-(quinoline-8-sulfonyl)-amino]-succinamide::CHEMBL342732 Disintegrin and metalloproteinase domain-containing protein 17 4500 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082958&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10840060 103982693 CHEMBL342732 ZINC27548899 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145931 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc(cc1)C#N)C(=O)NO)C(C)(C)C InChI=1S/C22H32N4O4S/c1-13(2)11-16(19(27)25-18(21(29)24-6)22(3,4)5)17(20(28)26-30)31-15-9-7-14(12-23)8-10-15/h7-10,13,16-18,30H,11H2,1-6H3,(H,24,29)(H,25,27)(H,26,28)/t16-,17+,18-/m1/s1 LDFJGSZPKVRXOC-FGTMMUONSA-N 50082939 (2S,3S)-2-(4-Cyano-phenylsulfanyl)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL342069 Disintegrin and metalloproteinase domain-containing protein 17 3300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082939&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10837188 103982674 CHEMBL342069 ZINC13802333 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145932 CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CC=C)C(=O)NO InChI=1S/C21H31N3O4/c1-5-9-16(20(26)24-28)17(12-14(2)3)19(25)23-18(21(27)22-4)13-15-10-7-6-8-11-15/h5-8,10-11,14,16-18,28H,1,9,12-13H2,2-4H3,(H,22,27)(H,23,25)(H,24,26)/t16-,17+,18-/m0/s1 GKHRDWHFKKUYAX-KSZLIROESA-N 50070453 (2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide::BB-1101::CHEMBL432079 Disintegrin and metalloproteinase domain-containing protein 17 2300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070453&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9908389 103964319 CHEMBL432079 ZINC03808476 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145933 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cccc2ccccc12)C(=O)NO)C(C)(C)C InChI=1S/C26H37N3O5/c1-16(2)14-20(23(30)28-22(25(32)27-6)26(3,4)5)21(24(31)29-33)34-15-18-12-9-11-17-10-7-8-13-19(17)18/h7-13,16,20-22,33H,14-15H2,1-6H3,(H,27,32)(H,28,30)(H,29,31)/t20-,21+,22-/m1/s1 HYZDDIKREGIJCH-BHIFYINESA-N 50082959 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalen-1-ylmethoxy)-succinamide::CHEMBL148373 Disintegrin and metalloproteinase domain-containing protein 17 0.33 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082959&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10528406 103982694 CHEMBL148373 ZINC13802401 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145934 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2c1nc[nH]c2=O)C(=O)NO)C(C)(C)C InChI=1S/C23H34N6O7S/c1-12(2)10-14(20(31)27-18(22(33)24-6)23(3,4)5)17(21(32)28-34)29-37(35,36)15-9-7-8-13-16(15)25-11-26-19(13)30/h7-9,11-12,14,17-18,29,34H,10H2,1-6H3,(H,24,33)(H,27,31)(H,28,32)(H,25,26,30)/t14-,17+,18-/m1/s1 WOGYYBSXXNJSRS-FHLIZLRMSA-N 50082956 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(4-oxo-3,4-dihydro-quinazoline-8-sulfonylamino)-succinamide::CHEMBL148048 Disintegrin and metalloproteinase domain-containing protein 17 4900 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10792503 103982691 CHEMBL148048 ZINC27553845 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145935 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2ncccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O6S/c1-14(2)12-17(21(30)27-20(23(32)25-6)24(3,4)5)19(22(31)28-33)29-36(34,35)16-9-10-18-15(13-16)8-7-11-26-18/h7-11,13-14,17,19-20,29,33H,12H2,1-6H3,(H,25,32)(H,27,30)(H,28,31)/t17-,19+,20-/m1/s1 JIZLXLHASQJXJD-YZGWKJHDSA-N 50082957 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinoline-6-sulfonylamino)-succinamide::CHEMBL344759 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10602072 103982692 CHEMBL344759 ZINC13802367 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145936 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cc2ccccc2n(C)c1=O)C(=O)NO)C(C)(C)C InChI=1S/C26H38N4O6/c1-15(2)12-18(22(31)28-21(24(33)27-6)26(3,4)5)20(23(32)29-35)36-14-17-13-16-10-8-9-11-19(16)30(7)25(17)34/h8-11,13,15,18,20-21,35H,12,14H2,1-7H3,(H,27,33)(H,28,31)(H,29,32)/t18-,20+,21-/m1/s1 NLDPPTDLJLPBHD-HLAWJBBLSA-N 50082948 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2-dihydro-quinolin-3-ylmethoxy)-succinamide::CHEMBL144101 Disintegrin and metalloproteinase domain-containing protein 17 0.44 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082948&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10696802 103982683 CHEMBL144101 ZINC13802395 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145937 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccnc1)C(=O)NO)C(C)(C)C InChI=1S/C20H33N5O6S/c1-12(2)10-14(17(26)23-16(19(28)21-6)20(3,4)5)15(18(27)24-29)25-32(30,31)13-8-7-9-22-11-13/h7-9,11-12,14-16,25,29H,10H2,1-6H3,(H,21,28)(H,23,26)(H,24,27)/t14-,15+,16-/m1/s1 AHPHIZBOHKHKMK-OWCLPIDISA-N 50082962 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(pyridine-3-sulfonylamino)-succinamide::CHEMBL146326 Disintegrin and metalloproteinase domain-containing protein 17 2.1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082962&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10719196 103982697 CHEMBL146326 ZINC13802355 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145938 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](SC)C(=O)NO)C(C)(C)C InChI=1S/C16H31N3O4S/c1-9(2)8-10(11(24-7)14(21)19-23)13(20)18-12(15(22)17-6)16(3,4)5/h9-12,23H,8H2,1-7H3,(H,17,22)(H,18,20)(H,19,21)/t10-,11+,12-/m1/s1 NRHLBEMLDGGLNI-GRYCIOLGSA-N 50082961 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-methylsulfanyl-succinamide::CHEMBL147091 Disintegrin and metalloproteinase domain-containing protein 17 2300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10666316 103982696 CHEMBL147091 ZINC13802342 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145942 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C22H36N4O4/c1-14(2)12-16(19(27)25-18(21(29)23-6)22(3,4)5)17(20(28)26-30)24-13-15-10-8-7-9-11-15/h7-11,14,16-18,24,30H,12-13H2,1-6H3,(H,23,29)(H,25,27)(H,26,28)/t16-,17+,18-/m1/s1 BEVXZSSVZCPHEU-FGTMMUONSA-N 50082966 (2R,3S)-2-Benzylamino-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL144021 Disintegrin and metalloproteinase domain-containing protein 17 2.8 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082966&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363482 103982701 CHEMBL144021 ZINC13802389 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145944 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc(F)cc1Cl)C(=O)NO)C(C)(C)C InChI=1S/C21H31ClFN3O4S/c1-11(2)9-13(18(27)25-17(20(29)24-6)21(3,4)5)16(19(28)26-30)31-15-8-7-12(23)10-14(15)22/h7-8,10-11,13,16-17,30H,9H2,1-6H3,(H,24,29)(H,25,27)(H,26,28)/t13-,16+,17-/m1/s1 LWBGYDKYPZYFIZ-XOKHGSTOSA-N 50082967 (2S,3S)-2-(2-Chloro-4-fluoro-phenylsulfanyl)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL436609 Disintegrin and metalloproteinase domain-containing protein 17 1.1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082967&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10600659 103982702 CHEMBL436609 ZINC13802338 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145945 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2N(C)C(=O)CCc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H39N5O7S/c1-14(2)12-17(22(32)27-21(24(34)26-6)25(3,4)5)20(23(33)28-35)29-38(36,37)16-9-10-18-15(13-16)8-11-19(31)30(18)7/h9-10,13-14,17,20-21,29,35H,8,11-12H2,1-7H3,(H,26,34)(H,27,32)(H,28,33)/t17-,20+,21-/m1/s1 PHLXTQREAVEZFN-JRGCBEDISA-N 50082968 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2,3,4-tetrahydro-quinoline-6-sulfonylamino)-succinamide::CHEMBL343021 Disintegrin and metalloproteinase domain-containing protein 17 3000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082968&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10745306 103982703 CHEMBL343021 ZINC27553648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145946 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc(cc1)S(C)(=O)=O)C(=O)NO)C(C)(C)C InChI=1S/C22H35N3O6S2/c1-13(2)12-16(19(26)24-18(21(28)23-6)22(3,4)5)17(20(27)25-29)32-14-8-10-15(11-9-14)33(7,30)31/h8-11,13,16-18,29H,12H2,1-7H3,(H,23,28)(H,24,26)(H,25,27)/t16-,17+,18-/m1/s1 KIUSNICXVJKQPC-FGTMMUONSA-N 50082969 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(4-methanesulfonyl-phenylsulfanyl)-succinamide::CHEMBL357898 Disintegrin and metalloproteinase domain-containing protein 17 2100 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082969&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11799603 103982704 CHEMBL357898 ZINC13802334 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145947 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCCCSC)C(=O)NO)C(C)(C)C InChI=1S/C19H38N4O4S/c1-12(2)11-13(14(17(25)23-27)21-9-8-10-28-7)16(24)22-15(18(26)20-6)19(3,4)5/h12-15,21,27H,8-11H2,1-7H3,(H,20,26)(H,22,24)(H,23,25)/t13-,14+,15-/m1/s1 IJOIQQOSGYLGFI-QLFBSQMISA-N 50082970 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(3-methylsulfanyl-propylamino)-succinamide::CHEMBL357446 Disintegrin and metalloproteinase domain-containing protein 17 4600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082970&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363479 103982705 CHEMBL357446 ZINC13802393 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145948 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2nc[nH]c(=O)c2c1)C(=O)NO)C(C)(C)C InChI=1S/C23H34N6O7S/c1-12(2)9-15(20(31)27-18(22(33)24-6)23(3,4)5)17(21(32)28-34)29-37(35,36)13-7-8-16-14(10-13)19(30)26-11-25-16/h7-8,10-12,15,17-18,29,34H,9H2,1-6H3,(H,24,33)(H,27,31)(H,28,32)(H,25,26,30)/t15-,17+,18-/m1/s1 GPENKXZRTRUYOG-BPQIPLTHSA-N 50082963 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(4-oxo-3,4-dihydro-quinazoline-6-sulfonylamino)-succinamide::CHEMBL342100 Disintegrin and metalloproteinase domain-containing protein 17 0.57 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10347173 103982698 CHEMBL342100 ZINC27552335 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145949 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O6S/c1-15(2)13-19(22(30)27-21(24(32)26-6)25(3,4)5)20(23(31)28-33)29-36(34,35)18-12-11-16-9-7-8-10-17(16)14-18/h7-12,14-15,19-21,29,33H,13H2,1-6H3,(H,26,32)(H,27,30)(H,28,31)/t19-,20+,21-/m1/s1 OMIBTIQYUVOLKA-QHAWAJNXSA-N 50082971 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalene-2-sulfonylamino)-succinamide::CHEMBL144283 Disintegrin and metalloproteinase domain-containing protein 17 0.66 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10744535 103982706 CHEMBL144283 ZINC13802359 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145950 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H36N4O5/c1-15(2)13-19(23(32)29-21(25(34)27-6)26(3,4)5)20(24(33)30-35)28-22(31)18-12-11-16-9-7-8-10-17(16)14-18/h7-12,14-15,19-21,35H,13H2,1-6H3,(H,27,34)(H,28,31)(H,29,32)(H,30,33)/t19-,20+,21-/m1/s1 KRYUMKRXIOHIFV-QHAWAJNXSA-N 50082972 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(naphthalene-2-carbonyl)-amino]-succinamide::CHEMBL144169 Disintegrin and metalloproteinase domain-containing protein 17 >20000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363576 103982707 CHEMBL144169 ZINC13802382 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145951 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1cc(Cl)cc(Cl)c1)C(=O)NO)C(C)(C)C InChI=1S/C21H31Cl2N3O4S/c1-11(2)7-15(18(27)25-17(20(29)24-6)21(3,4)5)16(19(28)26-30)31-14-9-12(22)8-13(23)10-14/h8-11,15-17,30H,7H2,1-6H3,(H,24,29)(H,25,27)(H,26,28)/t15-,16+,17-/m1/s1 WTCZFDOCEWZMII-IXDOHACOSA-N 50082974 (2S,3S)-2-(3,5-Dichloro-phenylsulfanyl)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL144736 Disintegrin and metalloproteinase domain-containing protein 17 4900 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082974&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11799315 103982709 CHEMBL144736 ZINC13802336 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145952 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2cnccc12)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O6S/c1-14(2)12-17(21(30)27-20(23(32)25-6)24(3,4)5)19(22(31)28-33)29-36(34,35)18-9-7-8-15-13-26-11-10-16(15)18/h7-11,13-14,17,19-20,29,33H,12H2,1-6H3,(H,25,32)(H,27,30)(H,28,31)/t17-,19+,20-/m1/s1 DNFCKYUQJJTPGW-YZGWKJHDSA-N 50082975 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(isoquinoline-5-sulfonylamino)-succinamide::CHEMBL144293 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10649665 103982710 CHEMBL144293 ZINC13802364 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145953 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2oc(=O)ccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H35N3O7/c1-14(2)11-17(22(30)27-21(24(32)26-6)25(3,4)5)20(23(31)28-33)34-13-15-7-9-18-16(12-15)8-10-19(29)35-18/h7-10,12,14,17,20-21,33H,11,13H2,1-6H3,(H,26,32)(H,27,30)(H,28,31)/t17-,20+,21-/m1/s1 URGPIZFOCVNKJR-JRGCBEDISA-N 50082976 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-oxo-2H-chromen-6-ylmethoxy)-succinamide::CHEMBL147383 Disintegrin and metalloproteinase domain-containing protein 17 0.79 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082976&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10601106 103982711 CHEMBL147383 ZINC13802403 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145956 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCCc1ccc2sc(C)nc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H38N4O5S/c1-14(2)12-17(22(30)28-21(24(32)26-7)25(4,5)6)20(23(31)29-33)34-11-10-16-8-9-19-18(13-16)27-15(3)35-19/h8-9,13-14,17,20-21,33H,10-12H2,1-7H3,(H,26,32)(H,28,30)(H,29,31)/t17-,20+,21-/m1/s1 DYPGYXPORHVYHH-JRGCBEDISA-N 50082973 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[2-(2-methyl-benzothiazol-5-yl)-ethoxy]-succinamide::CHEMBL147956 Disintegrin and metalloproteinase domain-containing protein 17 3500 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082973&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363562 103982708 CHEMBL147956 ZINC27555690 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145957 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1cc(Cl)cc(Cl)c1)C(=O)NO)C(C)(C)C InChI=1S/C21H31Cl2N3O4S/c1-11(2)7-15(18(27)25-17(20(29)24-6)21(3,4)5)16(19(28)26-30)31-14-9-12(22)8-13(23)10-14/h8-11,15-17,30H,7H2,1-6H3,(H,24,29)(H,25,27)(H,26,28)/t15-,16+,17-/m1/s1 WTCZFDOCEWZMII-IXDOHACOSA-N 50082974 (2S,3S)-2-(3,5-Dichloro-phenylsulfanyl)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL144736 Disintegrin and metalloproteinase domain-containing protein 17 0.42 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082974&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11799315 103982709 CHEMBL144736 ZINC13802336 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145958 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(=O)c1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H35N5O5/c1-14(2)13-17(22(32)29-20(24(34)26-6)25(3,4)5)19(23(33)30-35)28-21(31)16-11-7-9-15-10-8-12-27-18(15)16/h7-12,14,17,19-20,35H,13H2,1-6H3,(H,26,34)(H,28,31)(H,29,32)(H,30,33)/t17-,19+,20-/m1/s1 BKTXYTRQOBRSNS-YZGWKJHDSA-N 50082953 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinoline-8-carbonyl)-amino]-succinamide::CHEMBL144568 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082953&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15851477 103982688 CHEMBL144568 ZINC13802375 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145959 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N1CCOCC1)C(=O)NO)C(C)(C)C InChI=1S/C19H36N4O5/c1-12(2)11-13(14(17(25)22-27)23-7-9-28-10-8-23)16(24)21-15(18(26)20-6)19(3,4)5/h12-15,27H,7-11H2,1-6H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-/m1/s1 FTWOUUKMIDBQOJ-QLFBSQMISA-N 50082978 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-morpholin-4-yl-succinamide::CHEMBL144525 Disintegrin and metalloproteinase domain-containing protein 17 3000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082978&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10621015 103982713 CHEMBL144525 ZINC13802385 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145960 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O6S/c1-15(2)14-18(22(30)27-21(24(32)26-6)25(3,4)5)20(23(31)28-33)29-36(34,35)19-13-9-11-16-10-7-8-12-17(16)19/h7-13,15,18,20-21,29,33H,14H2,1-6H3,(H,26,32)(H,27,30)(H,28,31)/t18-,20+,21-/m1/s1 AFDRRXUDFSXQFE-HLAWJBBLSA-N 50082979 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalene-1-sulfonylamino)-succinamide::CHEMBL145069 Disintegrin and metalloproteinase domain-containing protein 17 3100 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082979&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10673548 103982714 CHEMBL145069 ZINC13802360 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145961 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cccc2nccnc12)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O5/c1-14(2)12-16(21(30)28-20(23(32)25-6)24(3,4)5)19(22(31)29-33)34-13-15-8-7-9-17-18(15)27-11-10-26-17/h7-11,14,16,19-20,33H,12-13H2,1-6H3,(H,25,32)(H,28,30)(H,29,31)/t16-,19+,20-/m1/s1 VQTLMFHSJXBYBD-LSTHTHJFSA-N 50082950 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinoxalin-5-ylmethoxy)-succinamide::CHEMBL148395 Disintegrin and metalloproteinase domain-containing protein 17 7600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082950&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10719273 103982685 CHEMBL148395 ZINC03821617 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145962 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N(Cc1ccccc1)S(=O)(=O)c1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C31H41N5O6S/c1-20(2)18-23(28(37)34-27(30(39)32-6)31(3,4)5)26(29(38)35-40)36(19-21-12-8-7-9-13-21)43(41,42)24-16-10-14-22-15-11-17-33-25(22)24/h7-17,20,23,26-27,40H,18-19H2,1-6H3,(H,32,39)(H,34,37)(H,35,38)/t23-,26+,27-/m1/s1 BYCSJLQSFICNET-DURWQBQJSA-N 50082977 (2R,3S)-2-[Benzyl-(quinoline-8-sulfonyl)-amino]-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL144832 Disintegrin and metalloproteinase domain-containing protein 17 85 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082977&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10770060 103982712 CHEMBL144832 ZINC27551606 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145963 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccs1)C(=O)NO)C(C)(C)C InChI=1S/C19H32N4O6S2/c1-11(2)10-12(16(24)21-15(18(26)20-6)19(3,4)5)14(17(25)22-27)23-31(28,29)13-8-7-9-30-13/h7-9,11-12,14-15,23,27H,10H2,1-6H3,(H,20,26)(H,21,24)(H,22,25)/t12-,14+,15-/m1/s1 VUYQZDVGRNXFIP-VHDGCEQUSA-N 50082984 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(thiophene-2-sulfonylamino)-succinamide::CHEMBL424492 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082984&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10648271 103982719 CHEMBL424492 ZINC13802353 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145964 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(=O)c1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H36N4O5/c1-15(2)13-19(23(32)29-21(25(34)27-6)26(3,4)5)20(24(33)30-35)28-22(31)18-12-11-16-9-7-8-10-17(16)14-18/h7-12,14-15,19-21,35H,13H2,1-6H3,(H,27,34)(H,28,31)(H,29,32)(H,30,33)/t19-,20+,21-/m1/s1 KRYUMKRXIOHIFV-QHAWAJNXSA-N 50082972 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(naphthalene-2-carbonyl)-amino]-succinamide::CHEMBL144169 Disintegrin and metalloproteinase domain-containing protein 17 3.3 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363576 103982707 CHEMBL144169 ZINC13802382 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145965 CCCN([C@@H]([C@@H](CC(C)C)C(=O)N[C@H](C(=O)NC)C(C)(C)C)C(=O)NO)S(=O)(=O)c1cccc2cccnc12 InChI=1S/C27H41N5O6S/c1-8-15-32(39(37,38)20-13-9-11-18-12-10-14-29-21(18)20)22(25(34)31-36)19(16-17(2)3)24(33)30-23(26(35)28-7)27(4,5)6/h9-14,17,19,22-23,36H,8,15-16H2,1-7H3,(H,28,35)(H,30,33)(H,31,34)/t19-,22+,23-/m1/s1 ZXOOAKIFEZRGLL-WTIAFYNJSA-N 50082982 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[propyl-(quinoline-8-sulfonyl)-amino]-succinamide::CHEMBL144144 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082982&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10698171 103982717 CHEMBL144144 ZINC27552085 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145966 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C22H36N4O4/c1-14(2)12-16(19(27)25-18(21(29)23-6)22(3,4)5)17(20(28)26-30)24-13-15-10-8-7-9-11-15/h7-11,14,16-18,24,30H,12-13H2,1-6H3,(H,23,29)(H,25,27)(H,26,28)/t16-,17+,18-/m1/s1 BEVXZSSVZCPHEU-FGTMMUONSA-N 50082966 (2R,3S)-2-Benzylamino-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL144021 Disintegrin and metalloproteinase domain-containing protein 17 6100 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082966&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363482 103982701 CHEMBL144021 ZINC13802389 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145967 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O5/c1-15(2)13-18(22(30)28-21(24(32)26-6)25(3,4)5)20(23(31)29-33)34-14-17-10-7-9-16-11-8-12-27-19(16)17/h7-12,15,18,20-21,33H,13-14H2,1-6H3,(H,26,32)(H,28,30)(H,29,31)/t18-,20+,21-/m1/s1 BRZXSVRUJXSSFG-HLAWJBBLSA-N 50082983 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinolin-8-ylmethoxy)-succinamide::CHEMBL144188 Disintegrin and metalloproteinase domain-containing protein 17 8200.0 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082983&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10814310 103982718 CHEMBL144188 ZINC13802397 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145968 CNC(=O)[C@@H](NC(=O)[C@H](CCCOCc1ccccc1)[C@H](OCc1ccc2nc(C)[nH]c(=O)c2c1)C(=O)NO)C(C)(C)C InChI=1S/C31H41N5O7/c1-19-33-24-14-13-21(16-23(24)28(38)34-19)18-43-25(29(39)36-41)22(12-9-15-42-17-20-10-7-6-8-11-20)27(37)35-26(30(40)32-5)31(2,3)4/h6-8,10-11,13-14,16,22,25-26,41H,9,12,15,17-18H2,1-5H3,(H,32,40)(H,35,37)(H,36,39)(H,33,34,38)/t22-,25+,26-/m1/s1 YJPYNLASIFTSPY-ZSQFBXSQSA-N 50082960 (2R,3S)-2-(3-Benzyloxy-propyl)-N*1*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-3-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethoxy)-succinamide::CHEMBL358962 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082960&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11801655 103982695 CHEMBL358962 ZINC04805533 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145969 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cc(Cl)cc(Cl)c1)C(=O)NO)C(C)(C)C InChI=1S/C21H32Cl2N4O6S/c1-11(2)7-15(18(28)25-17(20(30)24-6)21(3,4)5)16(19(29)26-31)27-34(32,33)14-9-12(22)8-13(23)10-14/h8-11,15-17,27,31H,7H2,1-6H3,(H,24,30)(H,25,28)(H,26,29)/t15-,16+,17-/m1/s1 UJIGCQOQCBITTE-IXDOHACOSA-N 50082981 (2R,3S)-2-(3,5-Dichloro-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL435683 Disintegrin and metalloproteinase domain-containing protein 17 11300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082981&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10602511 103982716 CHEMBL435683 ZINC27551249 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145970 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cnc[nH]1)C(=O)NO)C(C)(C)C InChI=1S/C18H32N6O6S/c1-10(2)7-11(15(25)22-14(17(27)19-6)18(3,4)5)13(16(26)23-28)24-31(29,30)12-8-20-9-21-12/h8-11,13-14,24,28H,7H2,1-6H3,(H,19,27)(H,20,21)(H,22,25)(H,23,26)/t11-,13+,14-/m1/s1 JUXPFZBFGMXKKR-KWCYVHTRSA-N 50082987 (2R,3S)-N*4*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-2-(3H-imidazole-4-sulfonylamino)-3-isobutyl-succinamide::CHEMBL144828 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082987&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363517 103982722 CHEMBL144828 ZINC27552306 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145971 CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1ccccc1)C(=O)NO InChI=1S/C25H33N3O4S/c1-17(2)14-20(21(24(30)28-32)16-33-19-12-8-5-9-13-19)23(29)27-22(25(31)26-3)15-18-10-6-4-7-11-18/h4-13,17,20-22,32H,14-16H2,1-3H3,(H,26,31)(H,27,29)(H,28,30)/t20-,21+,22+/m1/s1 UBFGIEDUTRCMEQ-FSSWDIPSSA-N 50069608 (2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-3-phenylsulfanylmethyl-succinamide::CHEMBL114427::GW-9471 Disintegrin and metalloproteinase domain-containing protein 17 1.8 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069608&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5748217 103963668 CHEMBL114427 ZINC03805534 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145972 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2oc(=O)ccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H35N3O7/c1-14(2)11-17(22(30)27-21(24(32)26-6)25(3,4)5)20(23(31)28-33)34-13-15-7-9-18-16(12-15)8-10-19(29)35-18/h7-10,12,14,17,20-21,33H,11,13H2,1-6H3,(H,26,32)(H,27,30)(H,28,31)/t17-,20+,21-/m1/s1 URGPIZFOCVNKJR-JRGCBEDISA-N 50082976 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-oxo-2H-chromen-6-ylmethoxy)-succinamide::CHEMBL147383 Disintegrin and metalloproteinase domain-containing protein 17 3600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082976&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10601106 103982711 CHEMBL147383 ZINC13802403 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145973 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCCc1ccc2sc(C)nc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H38N4O5S/c1-14(2)12-17(22(30)28-21(24(32)26-7)25(4,5)6)20(23(31)29-33)34-11-10-16-8-9-19-18(13-16)27-15(3)35-19/h8-9,13-14,17,20-21,33H,10-12H2,1-7H3,(H,26,32)(H,28,30)(H,29,31)/t17-,20+,21-/m1/s1 DYPGYXPORHVYHH-JRGCBEDISA-N 50082973 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[2-(2-methyl-benzothiazol-5-yl)-ethoxy]-succinamide::CHEMBL147956 Disintegrin and metalloproteinase domain-containing protein 17 0.21 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082973&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363562 103982708 CHEMBL147956 ZINC27555690 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145974 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O6S/c1-15(2)13-19(22(30)27-21(24(32)26-6)25(3,4)5)20(23(31)28-33)29-36(34,35)18-12-11-16-9-7-8-10-17(16)14-18/h7-12,14-15,19-21,29,33H,13H2,1-6H3,(H,26,32)(H,27,30)(H,28,31)/t19-,20+,21-/m1/s1 OMIBTIQYUVOLKA-QHAWAJNXSA-N 50082971 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalene-2-sulfonylamino)-succinamide::CHEMBL144283 Disintegrin and metalloproteinase domain-containing protein 17 1200 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10744535 103982706 CHEMBL144283 ZINC13802359 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145975 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccs1)C(=O)NO)C(C)(C)C InChI=1S/C19H32N4O6S2/c1-11(2)10-12(16(24)21-15(18(26)20-6)19(3,4)5)14(17(25)22-27)23-31(28,29)13-8-7-9-30-13/h7-9,11-12,14-15,23,27H,10H2,1-6H3,(H,20,26)(H,21,24)(H,22,25)/t12-,14+,15-/m1/s1 VUYQZDVGRNXFIP-VHDGCEQUSA-N 50082984 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(thiophene-2-sulfonylamino)-succinamide::CHEMBL424492 Disintegrin and metalloproteinase domain-containing protein 17 2800 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082984&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10648271 103982719 CHEMBL424492 ZINC13802353 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145976 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc2N(C)C(=O)CCc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H38N4O5S/c1-14(2)12-17(22(31)27-21(24(33)26-6)25(3,4)5)20(23(32)28-34)35-16-9-10-18-15(13-16)8-11-19(30)29(18)7/h9-10,13-14,17,20-21,34H,8,11-12H2,1-7H3,(H,26,33)(H,27,31)(H,28,32)/t17-,20+,21-/m1/s1 UINDEMWXTHSHSS-JRGCBEDISA-N 50082985 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylsulfanyl)-succinamide::CHEMBL147149 Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082985&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10601691 103982720 CHEMBL147149 ZINC13802331 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145977 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@@H](Sc1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C21H33N3O4S/c1-13(2)12-15(18(25)23-17(20(27)22-6)21(3,4)5)16(19(26)24-28)29-14-10-8-7-9-11-14/h7-11,13,15-17,28H,12H2,1-6H3,(H,22,27)(H,23,25)(H,24,26)/t15-,16-,17-/m1/s1 NSRKIPODZNWSLP-BRWVUGGUSA-N 50082986 (2S,3R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-phenylsulfanyl-succinamide::CHEMBL145128 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082986&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10550226 103982721 CHEMBL145128 ZINC13802328 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145978 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O5/c1-15(2)13-18(22(30)28-21(24(32)26-6)25(3,4)5)20(23(31)29-33)34-14-17-10-7-9-16-11-8-12-27-19(16)17/h7-12,15,18,20-21,33H,13-14H2,1-6H3,(H,26,32)(H,28,30)(H,29,31)/t18-,20+,21-/m1/s1 BRZXSVRUJXSSFG-HLAWJBBLSA-N 50082983 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinolin-8-ylmethoxy)-succinamide::CHEMBL144188 Disintegrin and metalloproteinase domain-containing protein 17 0.4 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082983&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10814310 103982718 CHEMBL144188 ZINC13802397 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145979 CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1ccccc1)C(=O)NO InChI=1S/C25H33N3O4S/c1-17(2)14-20(21(24(30)28-32)16-33-19-12-8-5-9-13-19)23(29)27-22(25(31)26-3)15-18-10-6-4-7-11-18/h4-13,17,20-22,32H,14-16H2,1-3H3,(H,26,31)(H,27,29)(H,28,30)/t20-,21+,22+/m1/s1 UBFGIEDUTRCMEQ-FSSWDIPSSA-N 50069608 (2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-3-phenylsulfanylmethyl-succinamide::CHEMBL114427::GW-9471 Disintegrin and metalloproteinase domain-containing protein 17 5300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50069608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50069608&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 5748217 103963668 CHEMBL114427 ZINC03805534 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145981 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc2N(C)C(=O)CCc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H38N4O5S/c1-14(2)12-17(22(31)27-21(24(33)26-6)25(3,4)5)20(23(32)28-34)35-16-9-10-18-15(13-16)8-11-19(30)29(18)7/h9-10,13-14,17,20-21,34H,8,11-12H2,1-7H3,(H,26,33)(H,27,31)(H,28,32)/t17-,20+,21-/m1/s1 UINDEMWXTHSHSS-JRGCBEDISA-N 50082985 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-6-ylsulfanyl)-succinamide::CHEMBL147149 Disintegrin and metalloproteinase domain-containing protein 17 6600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082985&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10601691 103982720 CHEMBL147149 ZINC13802331 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145982 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H37N3O5/c1-16(2)13-20(23(30)28-22(25(32)27-6)26(3,4)5)21(24(31)29-33)34-15-17-11-12-18-9-7-8-10-19(18)14-17/h7-12,14,16,20-22,33H,13,15H2,1-6H3,(H,27,32)(H,28,30)(H,29,31)/t20-,21+,22-/m1/s1 QWPOEQKVJCDSNI-BHIFYINESA-N 50082949 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalen-2-ylmethoxy)-succinamide::CHEMBL344312 Disintegrin and metalloproteinase domain-containing protein 17 7300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082949&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10504593 103982684 CHEMBL344312 ZINC13802404 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145983 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)CC(=O)NO)C(C)(C)C InChI=1S/C15H29N3O4/c1-9(2)7-10(8-11(19)18-22)13(20)17-12(14(21)16-6)15(3,4)5/h9-10,12,22H,7-8H2,1-6H3,(H,16,21)(H,17,20)(H,18,19)/t10-,12-/m1/s1 QRXOZHSEEGNRFC-ZYHUDNBSSA-N 50063920 (R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-succinamide::(R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::CHEMBL16520::Ro-31-9790 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063920&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9904965 103959092 CHEMBL16520 ZINC01534591 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145984 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(Br)cc1)C(=O)NO)C(C)(C)C InChI=1S/C21H33BrN4O6S/c1-12(2)11-15(18(27)24-17(20(29)23-6)21(3,4)5)16(19(28)25-30)26-33(31,32)14-9-7-13(22)8-10-14/h7-10,12,15-17,26,30H,11H2,1-6H3,(H,23,29)(H,24,27)(H,25,28)/t15-,16+,17-/m1/s1 UIJLTUOXWZPTFC-IXDOHACOSA-N 50082947 (2R,3S)-2-(4-Bromo-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL358129 Disintegrin and metalloproteinase domain-containing protein 17 4400 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363331 103982682 CHEMBL358129 ZINC27550633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145986 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(NC(C)=O)cc1)C(=O)NO)C(C)(C)C InChI=1S/C23H37N5O7S/c1-13(2)12-17(20(30)26-19(22(32)24-7)23(4,5)6)18(21(31)27-33)28-36(34,35)16-10-8-15(9-11-16)25-14(3)29/h8-11,13,17-19,28,33H,12H2,1-7H3,(H,24,32)(H,25,29)(H,26,30)(H,27,31)/t17-,18+,19-/m1/s1 WCAJZIQDOXGWAG-CEXWTWQISA-N 50082989 (2R,3S)-2-(4-Acetylamino-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL357414 Disintegrin and metalloproteinase domain-containing protein 17 1200 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082989&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10792259 103982724 CHEMBL357414 ZINC13802347 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145988 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2nc[nH]c(=O)c2c1)C(=O)NO)C(C)(C)C InChI=1S/C23H34N6O7S/c1-12(2)9-15(20(31)27-18(22(33)24-6)23(3,4)5)17(21(32)28-34)29-37(35,36)13-7-8-16-14(10-13)19(30)26-11-25-16/h7-8,10-12,15,17-18,29,34H,9H2,1-6H3,(H,24,33)(H,27,31)(H,28,32)(H,25,26,30)/t15-,17+,18-/m1/s1 GPENKXZRTRUYOG-BPQIPLTHSA-N 50082963 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(4-oxo-3,4-dihydro-quinazoline-6-sulfonylamino)-succinamide::CHEMBL342100 Disintegrin and metalloproteinase domain-containing protein 17 280 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10347173 103982698 CHEMBL342100 ZINC27552335 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145989 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N(C)S(=O)(=O)c1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C22H36N4O6S/c1-14(2)13-16(19(27)24-18(21(29)23-6)22(3,4)5)17(20(28)25-30)26(7)33(31,32)15-11-9-8-10-12-15/h8-12,14,16-18,30H,13H2,1-7H3,(H,23,29)(H,24,27)(H,25,28)/t16-,17+,18-/m1/s1 RMMUGCXFUHIPQO-FGTMMUONSA-N 50082980 (2R,3S)-2-(Benzenesulfonyl-methyl-amino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL344060 Disintegrin and metalloproteinase domain-containing protein 17 0.61 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082980&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10600908 103982715 CHEMBL344060 ZINC13802373 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145990 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H38N4O4/c1-16(2)13-20(23(31)29-22(25(33)27-6)26(3,4)5)21(24(32)30-34)28-15-17-11-12-18-9-7-8-10-19(18)14-17/h7-12,14,16,20-22,28,34H,13,15H2,1-6H3,(H,27,33)(H,29,31)(H,30,32)/t20-,21+,22-/m1/s1 LYBBNJPLEUKQHO-BHIFYINESA-N 50082988 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(naphthalen-2-ylmethyl)-amino]-succinamide::CHEMBL144001 Disintegrin and metalloproteinase domain-containing protein 17 6700 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082988&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11798586 103982723 CHEMBL144001 ZINC13802391 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145991 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(=O)c1ccc2ncccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H35N5O5/c1-14(2)12-17(22(32)29-20(24(34)26-6)25(3,4)5)19(23(33)30-35)28-21(31)16-9-10-18-15(13-16)8-7-11-27-18/h7-11,13-14,17,19-20,35H,12H2,1-6H3,(H,26,34)(H,28,31)(H,29,32)(H,30,33)/t17-,19+,20-/m1/s1 RGDWYVDESWNRAO-YZGWKJHDSA-N 50082990 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinoline-6-carbonyl)-amino]-succinamide::CHEMBL144267 Disintegrin and metalloproteinase domain-containing protein 17 9.5 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082990 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082990&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11799105 103982725 CHEMBL144267 ZINC13802377 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145992 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc2N(C)C(=O)CCc2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H39N5O7S/c1-14(2)12-17(22(32)27-21(24(34)26-6)25(3,4)5)20(23(33)28-35)29-38(36,37)16-9-10-18-15(13-16)8-11-19(31)30(18)7/h9-10,13-14,17,20-21,29,35H,8,11-12H2,1-7H3,(H,26,34)(H,27,32)(H,28,33)/t17-,20+,21-/m1/s1 PHLXTQREAVEZFN-JRGCBEDISA-N 50082968 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2,3,4-tetrahydro-quinoline-6-sulfonylamino)-succinamide::CHEMBL343021 Disintegrin and metalloproteinase domain-containing protein 17 2.9 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082968&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10745306 103982703 CHEMBL343021 ZINC27553648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145993 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N1CCOCC1)C(=O)NO)C(C)(C)C InChI=1S/C19H36N4O5/c1-12(2)11-13(14(17(25)22-27)23-7-9-28-10-8-23)16(24)21-15(18(26)20-6)19(3,4)5/h12-15,27H,7-11H2,1-6H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-/m1/s1 FTWOUUKMIDBQOJ-QLFBSQMISA-N 50082978 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-morpholin-4-yl-succinamide::CHEMBL144525 Disintegrin and metalloproteinase domain-containing protein 17 3.4 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082978&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10621015 103982713 CHEMBL144525 ZINC13802385 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145995 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O4/c1-15(2)13-18(22(31)29-21(24(33)26-6)25(3,4)5)20(23(32)30-34)28-14-17-10-7-9-16-11-8-12-27-19(16)17/h7-12,15,18,20-21,28,34H,13-14H2,1-6H3,(H,26,33)(H,29,31)(H,30,32)/t18-,20+,21-/m1/s1 DJQJEICJRBFEOV-HLAWJBBLSA-N 50082965 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinolin-8-ylmethyl)-amino]-succinamide::CHEMBL439983 Disintegrin and metalloproteinase domain-containing protein 17 0.23 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082965&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10695749 103982700 CHEMBL439983 ZINC13802388 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145996 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(C)(=O)=O)C(=O)NO)C(C)(C)C InChI=1S/C16H32N4O6S/c1-9(2)8-10(11(14(22)19-24)20-27(7,25)26)13(21)18-12(15(23)17-6)16(3,4)5/h9-12,20,24H,8H2,1-7H3,(H,17,23)(H,18,21)(H,19,22)/t10-,11+,12-/m1/s1 BQRRWAFUKIMCCQ-GRYCIOLGSA-N 50082992 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-methanesulfonylamino-succinamide::CHEMBL147542 Disintegrin and metalloproteinase domain-containing protein 17 1600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082992&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10787619 103982727 CHEMBL147542 ZINC13802372 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145998 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(=O)c1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H35N5O5/c1-14(2)13-17(22(32)29-20(24(34)26-6)25(3,4)5)19(23(33)30-35)28-21(31)16-11-7-9-15-10-8-12-27-18(15)16/h7-12,14,17,19-20,35H,13H2,1-6H3,(H,26,34)(H,28,31)(H,29,32)(H,30,33)/t17-,19+,20-/m1/s1 BKTXYTRQOBRSNS-YZGWKJHDSA-N 50082953 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinoline-8-carbonyl)-amino]-succinamide::CHEMBL144568 Disintegrin and metalloproteinase domain-containing protein 17 8000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082953&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15851477 103982688 CHEMBL144568 ZINC13802375 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50145999 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O4/c1-15(2)13-18(22(31)29-21(24(33)26-6)25(3,4)5)20(23(32)30-34)28-14-17-10-7-9-16-11-8-12-27-19(16)17/h7-12,15,18,20-21,28,34H,13-14H2,1-6H3,(H,26,33)(H,29,31)(H,30,32)/t18-,20+,21-/m1/s1 DJQJEICJRBFEOV-HLAWJBBLSA-N 50082965 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinolin-8-ylmethyl)-amino]-succinamide::CHEMBL439983 Disintegrin and metalloproteinase domain-containing protein 17 34000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082965&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10695749 103982700 CHEMBL439983 ZINC13802388 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146000 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cc2c(cc1Br)nc(C)[nH]c2=O)C(=O)NO)C(C)(C)C InChI=1S/C25H36BrN5O6/c1-12(2)8-16(22(33)30-20(24(35)27-7)25(4,5)6)19(23(34)31-36)37-11-14-9-15-18(10-17(14)26)28-13(3)29-21(15)32/h9-10,12,16,19-20,36H,8,11H2,1-7H3,(H,27,35)(H,30,33)(H,31,34)(H,28,29,32)/t16-,19+,20-/m1/s1 VMGWEPZCVOOZNU-LSTHTHJFSA-N 50082946 (2R,3S)-2-(7-Bromo-2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethoxy)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL357203 Disintegrin and metalloproteinase domain-containing protein 17 4300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082946&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10531330 103982681 CHEMBL357203 ZINC27553633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146001 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 7000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146002 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1cccc2ccccc12)C(=O)NO)C(C)(C)C InChI=1S/C26H37N3O5/c1-16(2)14-20(23(30)28-22(25(32)27-6)26(3,4)5)21(24(31)29-33)34-15-18-12-9-11-17-10-7-8-13-19(17)18/h7-13,16,20-22,33H,14-15H2,1-6H3,(H,27,32)(H,28,30)(H,29,31)/t20-,21+,22-/m1/s1 HYZDDIKREGIJCH-BHIFYINESA-N 50082959 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalen-1-ylmethoxy)-succinamide::CHEMBL148373 Disintegrin and metalloproteinase domain-containing protein 17 7600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082959&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10528406 103982694 CHEMBL148373 ZINC13802401 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146004 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 3.8 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146005 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](C1CCCC1)C(=O)NO)C(C)(C)C InChI=1S/C20H37N3O4/c1-12(2)11-14(15(18(25)23-27)13-9-7-8-10-13)17(24)22-16(19(26)21-6)20(3,4)5/h12-16,27H,7-11H2,1-6H3,(H,21,26)(H,22,24)(H,23,25)/t14-,15+,16-/m1/s1 QXLMMZHXXOWCDY-OWCLPIDISA-N 50082964 (2R,3S)-2-Cyclopentyl-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL29976 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082964&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9951986 103982699 CHEMBL29976 ZINC03821384 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146007 CCS[C@@H]([C@@H](CC(C)C)C(=O)N[C@H](C(=O)NC)C(C)(C)C)C(=O)NO InChI=1S/C17H33N3O4S/c1-8-25-12(15(22)20-24)11(9-10(2)3)14(21)19-13(16(23)18-7)17(4,5)6/h10-13,24H,8-9H2,1-7H3,(H,18,23)(H,19,21)(H,20,22)/t11-,12+,13-/m1/s1 ZGKUJTYUDXWQCL-FRRDWIJNSA-N 50082995 (2S,3S)-N*4*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-2-ethylsulfanyl-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL145836 Disintegrin and metalloproteinase domain-containing protein 17 5600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082995&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11793896 103982730 CHEMBL145836 ZINC13802344 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146008 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N1CCCC1)C(=O)NO)C(C)(C)C InChI=1S/C19H36N4O4/c1-12(2)11-13(14(17(25)22-27)23-9-7-8-10-23)16(24)21-15(18(26)20-6)19(3,4)5/h12-15,27H,7-11H2,1-6H3,(H,20,26)(H,21,24)(H,22,25)/t13-,14+,15-/m1/s1 YHQYCXXDVJZMED-QLFBSQMISA-N 50082941 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-pyrrolidin-1-yl-succinamide::CHEMBL144857 Disintegrin and metalloproteinase domain-containing protein 17 6100 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082941&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10572102 103982676 CHEMBL144857 ZINC13802386 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146009 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2n(C)c(=O)ccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H38N4O6/c1-15(2)12-18(23(32)28-22(25(34)27-6)26(3,4)5)21(24(33)29-35)36-14-16-8-10-19-17(13-16)9-11-20(31)30(19)7/h8-11,13,15,18,21-22,35H,12,14H2,1-7H3,(H,27,34)(H,28,32)(H,29,33)/t18-,21+,22-/m1/s1 JTCBZWXCQOLSNN-BVYCBKJFSA-N 50082991 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2-dihydro-quinolin-6-ylmethoxy)-succinamide::CHEMBL144611 Disintegrin and metalloproteinase domain-containing protein 17 1440 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082991&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9913990 103982726 CHEMBL144611 ZINC03821615 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146010 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(C)(=O)=O)C(=O)NO)C(C)(C)C InChI=1S/C16H32N4O6S/c1-9(2)8-10(11(14(22)19-24)20-27(7,25)26)13(21)18-12(15(23)17-6)16(3,4)5/h9-12,20,24H,8H2,1-7H3,(H,17,23)(H,18,21)(H,19,22)/t10-,11+,12-/m1/s1 BQRRWAFUKIMCCQ-GRYCIOLGSA-N 50082992 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-methanesulfonylamino-succinamide::CHEMBL147542 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082992 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082992&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10787619 103982727 CHEMBL147542 ZINC13802372 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146011 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2nc(C)[nH]c(=O)c2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O6/c1-13(2)10-17(22(32)29-20(24(34)26-7)25(4,5)6)19(23(33)30-35)36-12-15-8-9-18-16(11-15)21(31)28-14(3)27-18/h8-9,11,13,17,19-20,35H,10,12H2,1-7H3,(H,26,34)(H,29,32)(H,30,33)(H,27,28,31)/t17-,19+,20-/m1/s1 HVHNWBGVXFRQSU-YZGWKJHDSA-N 50082993 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethoxy)-succinamide::CHEMBL144229 Disintegrin and metalloproteinase domain-containing protein 17 2400 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082993&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10529484 103982728 CHEMBL144229 ZINC13802400 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146012 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(C)=O)C(=O)NO)C(C)(C)C InChI=1S/C17H32N4O5/c1-9(2)8-11(12(15(24)21-26)19-10(3)22)14(23)20-13(16(25)18-7)17(4,5)6/h9,11-13,26H,8H2,1-7H3,(H,18,25)(H,19,22)(H,20,23)(H,21,24)/t11-,12+,13-/m1/s1 IIQIBWBQUSDCNG-FRRDWIJNSA-N 50082997 (2R,3S)-2-Acetylamino-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL144845 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082997&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11793654 103982732 CHEMBL144845 ZINC13802383 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146013 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2nc(C)[nH]c(=O)c2c1)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O6/c1-13(2)10-17(22(32)29-20(24(34)26-7)25(4,5)6)19(23(33)30-35)36-12-15-8-9-18-16(11-15)21(31)28-14(3)27-18/h8-9,11,13,17,19-20,35H,10,12H2,1-7H3,(H,26,34)(H,29,32)(H,30,33)(H,27,28,31)/t17-,19+,20-/m1/s1 HVHNWBGVXFRQSU-YZGWKJHDSA-N 50082993 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-methyl-4-oxo-3,4-dihydro-quinazolin-6-ylmethoxy)-succinamide::CHEMBL144229 Disintegrin and metalloproteinase domain-containing protein 17 0.43 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082993&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10529484 103982728 CHEMBL144229 ZINC13802400 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146014 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccnc1)C(=O)NO)C(C)(C)C InChI=1S/C20H33N5O6S/c1-12(2)10-14(17(26)23-16(19(28)21-6)20(3,4)5)15(18(27)24-29)25-32(30,31)13-8-7-9-22-11-13/h7-9,11-12,14-16,25,29H,10H2,1-6H3,(H,21,28)(H,23,26)(H,24,27)/t14-,15+,16-/m1/s1 AHPHIZBOHKHKMK-OWCLPIDISA-N 50082962 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(pyridine-3-sulfonylamino)-succinamide::CHEMBL146326 Disintegrin and metalloproteinase domain-containing protein 17 3800 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082962&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10719196 103982697 CHEMBL146326 ZINC13802355 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146015 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](C1CCCC1)C(=O)NO)C(C)(C)C InChI=1S/C20H37N3O4/c1-12(2)11-14(15(18(25)23-27)13-9-7-8-10-13)17(24)22-16(19(26)21-6)20(3,4)5/h12-16,27H,7-11H2,1-6H3,(H,21,26)(H,22,24)(H,23,25)/t14-,15+,16-/m1/s1 QXLMMZHXXOWCDY-OWCLPIDISA-N 50082964 (2R,3S)-2-Cyclopentyl-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL29976 Disintegrin and metalloproteinase domain-containing protein 17 8800.0 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082964&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9951986 103982699 CHEMBL29976 ZINC03821384 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146016 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O6S/c1-14(2)13-16(21(30)27-20(23(32)25-6)24(3,4)5)19(22(31)28-33)29-36(34,35)17-11-7-9-15-10-8-12-26-18(15)17/h7-12,14,16,19-20,29,33H,13H2,1-6H3,(H,25,32)(H,27,30)(H,28,31)/t16-,19+,20-/m1/s1 MDENDLKFAFTBOF-LSTHTHJFSA-N 50082945 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinoline-8-sulfonylamino)-succinamide::CHEMBL144843 Disintegrin and metalloproteinase domain-containing protein 17 8100 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082945&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10602071 103982680 CHEMBL144843 ZINC13802362 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146018 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2ccccc12)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O6S/c1-15(2)14-18(22(30)27-21(24(32)26-6)25(3,4)5)20(23(31)28-33)29-36(34,35)19-13-9-11-16-10-7-8-12-17(16)19/h7-13,15,18,20-21,29,33H,14H2,1-6H3,(H,26,32)(H,27,30)(H,28,31)/t18-,20+,21-/m1/s1 AFDRRXUDFSXQFE-HLAWJBBLSA-N 50082979 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(naphthalene-1-sulfonylamino)-succinamide::CHEMBL145069 Disintegrin and metalloproteinase domain-containing protein 17 1.2 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082979&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10673548 103982714 CHEMBL145069 ZINC13802360 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146019 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccccc1C#N)C(=O)NO)C(C)(C)C InChI=1S/C22H33N5O6S/c1-13(2)11-15(19(28)25-18(21(30)24-6)22(3,4)5)17(20(29)26-31)27-34(32,33)16-10-8-7-9-14(16)12-23/h7-10,13,15,17-18,27,31H,11H2,1-6H3,(H,24,30)(H,25,28)(H,26,29)/t15-,17+,18-/m1/s1 VBARQQWZLRKFQP-BPQIPLTHSA-N 50082996 (2R,3S)-2-(2-Cyano-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL342777 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082996&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10696570 103982731 CHEMBL342777 ZINC13802349 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146020 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)CCc1ccncc1)C(=O)NO)C(C)(C)C InChI=1S/C22H37N5O6S/c1-14(2)13-16(19(28)25-18(21(30)23-6)22(3,4)5)17(20(29)26-31)27-34(32,33)12-9-15-7-10-24-11-8-15/h7-8,10-11,14,16-18,27,31H,9,12-13H2,1-6H3,(H,23,30)(H,25,28)(H,26,29)/t16-,17+,18-/m1/s1 KWTUEDAYOTUMEG-FGTMMUONSA-N 50082952 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(2-pyridin-4-yl-ethanesulfonylamino)-succinamide::CHEMBL144780 Disintegrin and metalloproteinase domain-containing protein 17 700 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082952&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10839079 103982687 CHEMBL144780 ZINC13802368 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146022 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCCCSC)C(=O)NO)C(C)(C)C InChI=1S/C19H38N4O4S/c1-12(2)11-13(14(17(25)23-27)21-9-8-10-28-7)16(24)22-15(18(26)20-6)19(3,4)5/h12-15,21,27H,8-11H2,1-7H3,(H,20,26)(H,22,24)(H,23,25)/t13-,14+,15-/m1/s1 IJOIQQOSGYLGFI-QLFBSQMISA-N 50082970 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(3-methylsulfanyl-propylamino)-succinamide::CHEMBL357446 Disintegrin and metalloproteinase domain-containing protein 17 1.3 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082970&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363479 103982705 CHEMBL357446 ZINC13802393 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146023 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc(OC)c(OC)c1)C(=O)NO)C(C)(C)C InChI=1S/C23H37N3O6S/c1-13(2)11-15(20(27)25-19(22(29)24-6)23(3,4)5)18(21(28)26-30)33-14-9-10-16(31-7)17(12-14)32-8/h9-10,12-13,15,18-19,30H,11H2,1-8H3,(H,24,29)(H,25,27)(H,26,28)/t15-,18+,19-/m1/s1 BHBFUQWAFABBLJ-AYOQOUSVSA-N 50082999 (2S,3S)-2-(3,4-Dimethoxy-phenylsulfanyl)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL147797 Disintegrin and metalloproteinase domain-containing protein 17 1.2 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082999&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10505010 103982734 CHEMBL147797 ZINC13802330 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146024 CNC(=O)[C@@H](NC(=O)[C@H](CCCCOCc1ccccc1)[C@H](OCc1ccc2n(C)c(=O)ncc2c1)C(=O)NO)C(C)(C)C InChI=1S/C32H43N5O7/c1-32(2,3)27(30(40)33-4)35-28(38)24(13-9-10-16-43-19-21-11-7-6-8-12-21)26(29(39)36-42)44-20-22-14-15-25-23(17-22)18-34-31(41)37(25)5/h6-8,11-12,14-15,17-18,24,26-27,42H,9-10,13,16,19-20H2,1-5H3,(H,33,40)(H,35,38)(H,36,39)/t24-,26+,27-/m1/s1 VOXBFNGVFFRNIE-FXVJXKIMSA-N 50082998 (2R,3S)-2-(4-Benzyloxy-butyl)-N*1*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-3-(1-methyl-2-oxo-1,2-dihydro-quinazolin-6-ylmethoxy)-succinamide::CHEMBL148331 Disintegrin and metalloproteinase domain-containing protein 17 0.8 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082998&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363783 103982733 CHEMBL148331 ZINC27554208 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146025 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1ccc2ccccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H38N4O4/c1-16(2)13-20(23(31)29-22(25(33)27-6)26(3,4)5)21(24(32)30-34)28-15-17-11-12-18-9-7-8-10-19(18)14-17/h7-12,14,16,20-22,28,34H,13,15H2,1-6H3,(H,27,33)(H,29,31)(H,30,32)/t20-,21+,22-/m1/s1 LYBBNJPLEUKQHO-BHIFYINESA-N 50082988 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(naphthalen-2-ylmethyl)-amino]-succinamide::CHEMBL144001 Disintegrin and metalloproteinase domain-containing protein 17 0.57 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082988 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082988&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11798586 103982723 CHEMBL144001 ZINC13802391 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146026 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1 YKPYIPVDTNNYCN-INIZCTEOSA-N 50082556 (S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::(S)-N-hydroxy-2,2-dimethyl-4-(4-(pyridin-4-yloxy)phenylsulfonyl)thiomorpholine-3-carboxamide::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(AG 3340)::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(prinomastat)::AG-3340::CHEMBL75094::Prinomastat Disintegrin and metalloproteinase domain-containing protein 17 16600 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082556&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search PN0 3QM4,3TDA,6CSD 466151 103982334 CHEMBL75094 6505 ZINC00580328 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146027 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(cc1)C(O)=O)C(=O)NO)C(C)(C)C InChI=1S/C22H34N4O8S/c1-12(2)11-15(18(27)24-17(20(29)23-6)22(3,4)5)16(19(28)25-32)26-35(33,34)14-9-7-13(8-10-14)21(30)31/h7-10,12,15-17,26,32H,11H2,1-6H3,(H,23,29)(H,24,27)(H,25,28)(H,30,31)/t15-,16+,17-/m1/s1 RPMOOSCCVXWNFA-IXDOHACOSA-N 50083000 4-[(1S,2R)-2-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-1-hydroxycarbamoyl-4-methyl-pentylsulfamoyl]-benzoic acid::CHEMBL145684 Disintegrin and metalloproteinase domain-containing protein 17 3.2 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083000&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363311 103982735 CHEMBL145684 ZINC13802357 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146029 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cc(Cl)cc(Cl)c1)C(=O)NO)C(C)(C)C InChI=1S/C21H32Cl2N4O6S/c1-11(2)7-15(18(28)25-17(20(30)24-6)21(3,4)5)16(19(29)26-31)27-34(32,33)14-9-12(22)8-13(23)10-14/h8-11,15-17,27,31H,7H2,1-6H3,(H,24,30)(H,25,28)(H,26,29)/t15-,16+,17-/m1/s1 UJIGCQOQCBITTE-IXDOHACOSA-N 50082981 (2R,3S)-2-(3,5-Dichloro-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL435683 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082981&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10602511 103982716 CHEMBL435683 ZINC27551249 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146030 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OCc1ccc2n(C)c(=O)ccc2c1)C(=O)NO)C(C)(C)C InChI=1S/C26H38N4O6/c1-15(2)12-18(23(32)28-22(25(34)27-6)26(3,4)5)21(24(33)29-35)36-14-16-8-10-19-17(13-16)9-11-20(31)30(19)7/h8-11,13,15,18,21-22,35H,12,14H2,1-7H3,(H,27,34)(H,28,32)(H,29,33)/t18-,21+,22-/m1/s1 JTCBZWXCQOLSNN-BVYCBKJFSA-N 50082991 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(1-methyl-2-oxo-1,2-dihydro-quinolin-6-ylmethoxy)-succinamide::CHEMBL144611 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082991 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082991&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9913990 103982726 CHEMBL144611 ZINC03821615 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146031 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc(cc1)S(C)(=O)=O)C(=O)NO)C(C)(C)C InChI=1S/C22H35N3O6S2/c1-13(2)12-16(19(26)24-18(21(28)23-6)22(3,4)5)17(20(27)25-29)32-14-8-10-15(11-9-14)33(7,30)31/h8-11,13,16-18,29H,12H2,1-7H3,(H,23,28)(H,24,26)(H,25,27)/t16-,17+,18-/m1/s1 KIUSNICXVJKQPC-FGTMMUONSA-N 50082969 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(4-methanesulfonyl-phenylsulfanyl)-succinamide::CHEMBL357898 Disintegrin and metalloproteinase domain-containing protein 17 1.25 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082969&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11799603 103982704 CHEMBL357898 ZINC13802334 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146032 CCS[C@@H]([C@@H](CC(C)C)C(=O)N[C@H](C(=O)NC)C(C)(C)C)C(=O)NO InChI=1S/C17H33N3O4S/c1-8-25-12(15(22)20-24)11(9-10(2)3)14(21)19-13(16(23)18-7)17(4,5)6/h10-13,24H,8-9H2,1-7H3,(H,18,23)(H,19,21)(H,20,22)/t11-,12+,13-/m1/s1 ZGKUJTYUDXWQCL-FRRDWIJNSA-N 50082995 (2S,3S)-N*4*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-2-ethylsulfanyl-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL145836 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082995&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11793896 103982730 CHEMBL145836 ZINC13802344 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146033 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](N(C)S(=O)(=O)c1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C22H36N4O6S/c1-14(2)13-16(19(27)24-18(21(29)23-6)22(3,4)5)17(20(28)25-30)26(7)33(31,32)15-11-9-8-10-12-15/h8-12,14,16-18,30H,13H2,1-7H3,(H,23,29)(H,24,27)(H,25,28)/t16-,17+,18-/m1/s1 RMMUGCXFUHIPQO-FGTMMUONSA-N 50082980 (2R,3S)-2-(Benzenesulfonyl-methyl-amino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL344060 Disintegrin and metalloproteinase domain-containing protein 17 3000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082980&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10600908 103982715 CHEMBL344060 ZINC13802373 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146034 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1 YKPYIPVDTNNYCN-INIZCTEOSA-N 50082556 (S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::(S)-N-hydroxy-2,2-dimethyl-4-(4-(pyridin-4-yloxy)phenylsulfonyl)thiomorpholine-3-carboxamide::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(AG 3340)::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(prinomastat)::AG-3340::CHEMBL75094::Prinomastat Disintegrin and metalloproteinase domain-containing protein 17 5.5 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082556&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search PN0 3QM4,3TDA,6CSD 466151 103982334 CHEMBL75094 6505 ZINC00580328 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146036 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1ccc2ccccc2n1)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O4/c1-15(2)13-18(22(31)29-21(24(33)26-6)25(3,4)5)20(23(32)30-34)27-14-17-12-11-16-9-7-8-10-19(16)28-17/h7-12,15,18,20-21,27,34H,13-14H2,1-6H3,(H,26,33)(H,29,31)(H,30,32)/t18-,20+,21-/m1/s1 NOJJACCRGJNXQC-HLAWJBBLSA-N 50083001 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinolin-2-ylmethyl)-amino]-succinamide::CHEMBL359217 Disintegrin and metalloproteinase domain-containing protein 17 5700 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083001&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10504595 103982736 CHEMBL359217 ZINC13802392 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146037 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(cc1)C(O)=O)C(=O)NO)C(C)(C)C InChI=1S/C22H34N4O8S/c1-12(2)11-15(18(27)24-17(20(29)23-6)22(3,4)5)16(19(28)25-32)26-35(33,34)14-9-7-13(8-10-14)21(30)31/h7-10,12,15-17,26,32H,11H2,1-6H3,(H,23,29)(H,24,27)(H,25,28)(H,30,31)/t15-,16+,17-/m1/s1 RPMOOSCCVXWNFA-IXDOHACOSA-N 50083000 4-[(1S,2R)-2-((S)-2,2-Dimethyl-1-methylcarbamoyl-propylcarbamoyl)-1-hydroxycarbamoyl-4-methyl-pentylsulfamoyl]-benzoic acid::CHEMBL145684 Disintegrin and metalloproteinase domain-containing protein 17 4400 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083000&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363311 103982735 CHEMBL145684 ZINC13802357 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146038 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccc(NC(C)=O)cc1)C(=O)NO)C(C)(C)C InChI=1S/C23H37N5O7S/c1-13(2)12-17(20(30)26-19(22(32)24-7)23(4,5)6)18(21(31)27-33)28-36(34,35)16-10-8-15(9-11-16)25-14(3)29/h8-11,13,17-19,28,33H,12H2,1-7H3,(H,24,32)(H,25,29)(H,26,30)(H,27,31)/t17-,18+,19-/m1/s1 WCAJZIQDOXGWAG-CEXWTWQISA-N 50082989 (2R,3S)-2-(4-Acetylamino-benzenesulfonylamino)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL357414 Disintegrin and metalloproteinase domain-containing protein 17 1.3 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082989 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082989&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10792259 103982724 CHEMBL357414 ZINC13802347 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146039 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C21H34N4O6S/c1-13(2)12-15(18(26)23-17(20(28)22-6)21(3,4)5)16(19(27)24-29)25-32(30,31)14-10-8-7-9-11-14/h7-11,13,15-17,25,29H,12H2,1-6H3,(H,22,28)(H,23,26)(H,24,27)/t15-,16+,17-/m1/s1 XWRQKKZZTBPBOK-IXDOHACOSA-N 50083002 (2R,3S)-2-Benzenesulfonylamino-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL356259 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083002&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9847528 103982737 CHEMBL356259 ZINC13802345 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146040 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NCc1ccc2ccccc2n1)C(=O)NO)C(C)(C)C InChI=1S/C25H37N5O4/c1-15(2)13-18(22(31)29-21(24(33)26-6)25(3,4)5)20(23(32)30-34)27-14-17-12-11-16-9-7-8-10-19(16)28-17/h7-12,15,18,20-21,27,34H,13-14H2,1-6H3,(H,26,33)(H,29,31)(H,30,32)/t18-,20+,21-/m1/s1 NOJJACCRGJNXQC-HLAWJBBLSA-N 50083001 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(quinolin-2-ylmethyl)-amino]-succinamide::CHEMBL359217 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083001&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10504595 103982736 CHEMBL359217 ZINC13802392 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146041 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1cccc2cnccc12)C(=O)NO)C(C)(C)C InChI=1S/C24H35N5O6S/c1-14(2)12-17(21(30)27-20(23(32)25-6)24(3,4)5)19(22(31)28-33)29-36(34,35)18-9-7-8-15-13-26-11-10-16(15)18/h7-11,13-14,17,19-20,29,33H,12H2,1-6H3,(H,25,32)(H,27,30)(H,28,31)/t17-,19+,20-/m1/s1 DNFCKYUQJJTPGW-YZGWKJHDSA-N 50082975 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(isoquinoline-5-sulfonylamino)-succinamide::CHEMBL144293 Disintegrin and metalloproteinase domain-containing protein 17 3.1 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10649665 103982710 CHEMBL144293 ZINC13802364 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146042 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](OC)C(=O)NO)C(C)(C)C InChI=1S/C16H31N3O5/c1-9(2)8-10(11(24-7)14(21)19-23)13(20)18-12(15(22)17-6)16(3,4)5/h9-12,23H,8H2,1-7H3,(H,17,22)(H,18,20)(H,19,21)/t10-,11+,12-/m1/s1 AJIRKSAIZYDGMB-GRYCIOLGSA-N 50082940 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-methoxy-succinamide::CHEMBL357195 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082940&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9928154 103982675 CHEMBL357195 ZINC13802398 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146043 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1cccc(c1)C(C)(C)C#N)C(=O)NO)C(C)(C)C InChI=1S/C25H38N4O4S/c1-15(2)12-18(21(30)28-20(23(32)27-8)24(3,4)5)19(22(31)29-33)34-17-11-9-10-16(13-17)25(6,7)14-26/h9-11,13,15,18-20,33H,12H2,1-8H3,(H,27,32)(H,28,30)(H,29,31)/t18-,19+,20-/m1/s1 QDIXPUMJVOLKDW-HSALFYBXSA-N 50082944 (2S,3S)-2-[3-(Cyano-dimethyl-methyl)-phenylsulfanyl]-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL355900 Disintegrin and metalloproteinase domain-containing protein 17 2800 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082944&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10577036 103982679 CHEMBL355900 ZINC13802340 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146044 CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CC=C)C(=O)NO InChI=1S/C21H31N3O4/c1-5-9-16(20(26)24-28)17(12-14(2)3)19(25)23-18(21(27)22-4)13-15-10-7-6-8-11-15/h5-8,10-11,14,16-18,28H,1,9,12-13H2,2-4H3,(H,22,27)(H,23,25)(H,24,26)/t16-,17+,18-/m0/s1 GKHRDWHFKKUYAX-KSZLIROESA-N 50070453 (2R,3S)-2-Allyl-N*1*-hydroxy-3-isobutyl-N*4*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-succinamide::BB-1101::CHEMBL432079 Disintegrin and metalloproteinase domain-containing protein 17 0.2 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50070453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50070453&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9908389 103964319 CHEMBL432079 ZINC03808476 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146045 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C21H33N3O4S/c1-13(2)12-15(18(25)23-17(20(27)22-6)21(3,4)5)16(19(26)24-28)29-14-10-8-7-9-11-14/h7-11,13,15-17,28H,12H2,1-6H3,(H,22,27)(H,23,25)(H,24,26)/t15-,16+,17-/m1/s1 NSRKIPODZNWSLP-IXDOHACOSA-N 50083003 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-phenylsulfanyl-succinamide::CHEMBL145137 Disintegrin and metalloproteinase domain-containing protein 17 188 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083003&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9866988 103982738 CHEMBL145137 ZINC03821458 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146046 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NC(=O)c1cccnc1)C(=O)NO)C(C)(C)C InChI=1S/C21H33N5O5/c1-12(2)10-14(18(28)25-16(20(30)22-6)21(3,4)5)15(19(29)26-31)24-17(27)13-8-7-9-23-11-13/h7-9,11-12,14-16,31H,10H2,1-6H3,(H,22,30)(H,24,27)(H,25,28)(H,26,29)/t14-,15+,16-/m1/s1 SBRIIQLJHOIYAI-OWCLPIDISA-N 50083004 (2R,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-[(pyridine-3-carbonyl)-amino]-succinamide::CHEMBL144095 Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083004&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363290 103982739 CHEMBL144095 ZINC13802379 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146047 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](SCc1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O4S/c1-15(2)13-18(22(30)28-21(24(32)26-6)25(3,4)5)20(23(31)29-33)34-14-17-10-7-9-16-11-8-12-27-19(16)17/h7-12,15,18,20-21,33H,13-14H2,1-6H3,(H,26,32)(H,28,30)(H,29,31)/t18-,20+,21-/m1/s1 YAWCEEHWRJZVNM-HLAWJBBLSA-N 50082994 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinolin-8-ylmethylsulfanyl)-succinamide::CHEMBL147051 Disintegrin and metalloproteinase domain-containing protein 17 6200 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082994&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15851478 103982729 CHEMBL147051 ZINC13802339 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146048 CNC(=O)[C@@H](NC(=O)[C@H](CCCCOCc1ccccc1)[C@H](OCc1ccc2n(C)c(=O)ncc2c1)C(=O)NO)C(C)(C)C InChI=1S/C32H43N5O7/c1-32(2,3)27(30(40)33-4)35-28(38)24(13-9-10-16-43-19-21-11-7-6-8-12-21)26(29(39)36-42)44-20-22-14-15-25-23(17-22)18-34-31(41)37(25)5/h6-8,11-12,14-15,17-18,24,26-27,42H,9-10,13,16,19-20H2,1-5H3,(H,33,40)(H,35,38)(H,36,39)/t24-,26+,27-/m1/s1 VOXBFNGVFFRNIE-FXVJXKIMSA-N 50082998 (2R,3S)-2-(4-Benzyloxy-butyl)-N*1*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-3-(1-methyl-2-oxo-1,2-dihydro-quinazolin-6-ylmethoxy)-succinamide::CHEMBL148331 Disintegrin and metalloproteinase domain-containing protein 17 6500 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082998&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44363783 103982733 CHEMBL148331 ZINC27554208 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146049 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](SC)C(=O)NO)C(C)(C)C InChI=1S/C16H31N3O4S/c1-9(2)8-10(11(24-7)14(21)19-23)13(20)18-12(15(22)17-6)16(3,4)5/h9-12,23H,8H2,1-7H3,(H,17,22)(H,18,20)(H,19,21)/t10-,11+,12-/m1/s1 NRHLBEMLDGGLNI-GRYCIOLGSA-N 50082961 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-methylsulfanyl-succinamide::CHEMBL147091 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10666316 103982696 CHEMBL147091 ZINC13802342 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146052 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](Sc1ccc(F)cc1Cl)C(=O)NO)C(C)(C)C InChI=1S/C21H31ClFN3O4S/c1-11(2)9-13(18(27)25-17(20(29)24-6)21(3,4)5)16(19(28)26-30)31-15-8-7-12(23)10-14(15)22/h7-8,10-11,13,16-17,30H,9H2,1-6H3,(H,24,29)(H,25,27)(H,26,28)/t13-,16+,17-/m1/s1 LWBGYDKYPZYFIZ-XOKHGSTOSA-N 50082967 (2S,3S)-2-(2-Chloro-4-fluoro-phenylsulfanyl)-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL436609 Disintegrin and metalloproteinase domain-containing protein 17 11000 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082967&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10600659 103982702 CHEMBL436609 ZINC13802338 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146053 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](NS(=O)(=O)c1ccccc1)C(=O)NO)C(C)(C)C InChI=1S/C21H34N4O6S/c1-13(2)12-15(18(26)23-17(20(28)22-6)21(3,4)5)16(19(27)24-29)25-32(30,31)14-10-8-7-9-11-14/h7-11,13,15-17,25,29H,12H2,1-6H3,(H,22,28)(H,23,26)(H,24,27)/t15-,16+,17-/m1/s1 XWRQKKZZTBPBOK-IXDOHACOSA-N 50083002 (2R,3S)-2-Benzenesulfonylamino-N*4*-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-3-isobutyl-succinamide::CHEMBL356259 Disintegrin and metalloproteinase domain-containing protein 17 1300 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50083002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50083002&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9847528 103982737 CHEMBL356259 ZINC13802345 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50146054 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](SCc1cccc2cccnc12)C(=O)NO)C(C)(C)C InChI=1S/C25H36N4O4S/c1-15(2)13-18(22(30)28-21(24(32)26-6)25(3,4)5)20(23(31)29-33)34-14-17-10-7-9-16-11-8-12-27-19(16)17/h7-12,15,18,20-21,33H,13-14H2,1-6H3,(H,26,32)(H,28,30)(H,29,31)/t18-,20+,21-/m1/s1 YAWCEEHWRJZVNM-HLAWJBBLSA-N 50082994 (2S,3S)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-3-(quinolin-8-ylmethylsulfanyl)-succinamide::CHEMBL147051 Disintegrin and metalloproteinase domain-containing protein 17 0.8 ChEMBL 10.1021/jm990377j 10.7270/Q2HM57NS 10579851 Barlaam, B; Bird, TG; Lambert-Van Der Brempt, C; Campbell, D; Foster, SJ; Maciewicz, R AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082994&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15851478 103982729 CHEMBL147051 ZINC13802339 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50156528 OC(CCc1ccc(cc1)-c1ccccc1)CC(O)=O InChI=1S/C17H18O3/c18-16(12-17(19)20)11-8-13-6-9-15(10-7-13)14-4-2-1-3-5-14/h1-7,9-10,16,18H,8,11-12H2,(H,19,20) ILGSIIFHQGOKKV-UHFFFAOYSA-N 50300465 (+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid::5-(biphenyl-4-yl)-3-hydroxypentanoic acid::CHEMBL572982 Disintegrin and metalloproteinase domain-containing protein 17 >98000 ChEMBL 10.1016/j.bmcl.2009.07.155 10.7270/Q2RR1Z91 19703773 Holmes, IP; Gaines, S; Watson, SP; Lorthioir, O; Walker, A; Baddeley, SJ; Herbert, S; Egan, D; Convery, MA; Singh, OM; Gross, JW; Strelow, JM; Smith, RH; Amour, AJ; Brown, D; Martin, SL GSK Medicines Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 077 2WO8 11391583 104154826 CHEMBL572982 C03834 ZINC45285504 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50153053 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O InChI=1S/C28H26N2O6S/c1-2-3-15-35-22-9-12-24(13-10-22)37(33,34)30-27(28(31)32)16-21-18-29-26-14-11-23(17-25(21)26)36-19-20-7-5-4-6-8-20/h4-14,17-18,27,29-30H,15-16,19H2,1H3,(H,31,32) OPSGGAROSGLASJ-UHFFFAOYSA-N 50279287 3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid::CHEMBL463395::rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-benzyloxy-1H-indol-3-yl)-propionic acid Disintegrin and metalloproteinase domain-containing protein 17 6980 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279287&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11533683 104121271 CHEMBL463395 ZINC34621352 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50153054 COc1ccc2[nH]cc(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C22H22N2O6S/c1-3-4-11-30-16-5-8-18(9-6-16)31(27,28)24-21(22(25)26)12-15-14-23-20-10-7-17(29-2)13-19(15)20/h5-10,13-14,21,23-24H,11-12H2,1-2H3,(H,25,26) QBMRYLHKTSDMJW-UHFFFAOYSA-N 50279257 2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-1H-indol-3-yl)propanoic acid::CHEMBL497908::rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-methoxy-1H-indol-3-yl)-propionic acid Disintegrin and metalloproteinase domain-containing protein 17 10100 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279257&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11510523 104121254 CHEMBL497908 ZINC40976006 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161333 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161336 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 800 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161337 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 420 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161338 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 1400 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161340 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 1600 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161359 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 420 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161360 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 500 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161362 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 760 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161366 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 73 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161375 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 110 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161381 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 280 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161396 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 260 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161403 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161425 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 380 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161440 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 1400 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161446 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 13000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161448 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 110 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161464 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 750 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161471 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 750 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161474 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 4400 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161478 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 18000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161487 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161518 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 2600 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161519 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 550 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161520 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 890 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161521 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 51 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161522 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 3.2 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161523 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 53 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161524 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 4.3 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161525 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 1700 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161526 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 90 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161528 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 97 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161529 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161530 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 0.700000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161531 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161538 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 3000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161539 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 3200 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50161540 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 6900 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169338 Cc1ccc2oc(=O)c(CC(CCCc3ccc(OCCN4CCCCC4)cc3)C(=O)NO)cc2c1 InChI=1S/C29H36N2O5/c1-21-8-13-27-24(18-21)20-25(29(33)36-27)19-23(28(32)30-34)7-5-6-22-9-11-26(12-10-22)35-17-16-31-14-3-2-4-15-31/h8-13,18,20,23,34H,2-7,14-17,19H2,1H3,(H,30,32) JAZDDPKAAYCQHV-UHFFFAOYSA-N 50332475 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-5-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-pentanoic acid hydroxyamide::CHEMBL1630105 Disintegrin and metalloproteinase domain-containing protein 17 320 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332475&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986869 125082577 CHEMBL1630105 ZINC34853085 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169339 Cc1ccc2oc(=O)c(CC(CCc3cccc(OCCN4CCCCC4)c3)C(=O)NO)cc2c1 InChI=1S/C28H34N2O5/c1-20-8-11-26-23(16-20)19-24(28(32)35-26)18-22(27(31)29-33)10-9-21-6-5-7-25(17-21)34-15-14-30-12-3-2-4-13-30/h5-8,11,16-17,19,22,33H,2-4,9-10,12-15,18H2,1H3,(H,29,31) MYFAXYOWANOMSJ-UHFFFAOYSA-N 50332474 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-4-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-butanoic acid hydroxyamide::CHEMBL1630104 Disintegrin and metalloproteinase domain-containing protein 17 240 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332474&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53316692 125082576 CHEMBL1630104 ZINC66260208 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169340 CN(C)CCOc1ccc(CCC(Cc2cc3cc(C)ccc3oc2=O)C(=O)NO)cc1 InChI=1S/C25H30N2O5/c1-17-4-11-23-20(14-17)16-21(25(29)32-23)15-19(24(28)26-30)8-5-18-6-9-22(10-7-18)31-13-12-27(2)3/h4,6-7,9-11,14,16,19,30H,5,8,12-13,15H2,1-3H3,(H,26,28) WRLLSTLVYRVAEC-UHFFFAOYSA-N 50332477 4-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-((6-methyl-2-oxo-2H-chromen-3-yl)-methyl)butanoic acid hydroxyamide::CHEMBL1630088 Disintegrin and metalloproteinase domain-containing protein 17 0.660000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332477&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986256 125082579 CHEMBL1630088 ZINC34851710 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169341 Cc1ccc2oc(=O)c(CC(CCc3ccc(OCCN4CCCCC4)cc3)C(=O)NO)cc2c1 InChI=1S/C28H34N2O5/c1-20-5-12-26-23(17-20)19-24(28(32)35-26)18-22(27(31)29-33)9-6-21-7-10-25(11-8-21)34-16-15-30-13-3-2-4-14-30/h5,7-8,10-12,17,19,22,33H,2-4,6,9,13-16,18H2,1H3,(H,29,31) GOUYMPANMMVPFE-UHFFFAOYSA-N 50332473 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-4-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-butanoic acid hydroxyamide::CHEMBL1630103 Disintegrin and metalloproteinase domain-containing protein 17 200 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332473&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986607 125082575 CHEMBL1630103 ZINC34852490 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169342 CC(C)[C@@H](N1CC[C@](N)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C26H30N4O4/c1-16(2)23(24(31)29-33)30-13-12-26(27,25(30)32)19-8-10-20(11-9-19)34-15-18-14-17(3)28-22-7-5-4-6-21(18)22/h4-11,14,16,23,33H,12-13,15,27H2,1-3H3,(H,29,31)/t23-,26-/m1/s1 VINTZLVANMVXOH-ZEQKJWHPSA-N 50332481 (R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-3-methylbutanamide::CHEMBL1630098 Disintegrin and metalloproteinase domain-containing protein 17 0.100000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332481&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53320639 125082583 CHEMBL1630098 ZINC38842829 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169343 Cc1ccc2oc(=O)c(CC(Cc3ccccc3)C(=O)NO)cc2c1 InChI=1S/C20H19NO4/c1-13-7-8-18-15(9-13)11-17(20(23)25-18)12-16(19(22)21-24)10-14-5-3-2-4-6-14/h2-9,11,16,24H,10,12H2,1H3,(H,21,22) UOINUECLJZQMHR-UHFFFAOYSA-N 50224961 2-benzyl-N-hydroxy-3-(6-methyl-2-oxo-2H-chromen-3-yl)-propionamide::CHEMBL402030 Disintegrin and metalloproteinase domain-containing protein 17 520 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986113 104096474 CHEMBL402030 ZINC28979017 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169344 Cc1ccc2oc(=O)c(CC(CCCc3cccc(OCCN4CCCCC4)c3)C(=O)NO)cc2c1 InChI=1S/C29H36N2O5/c1-21-11-12-27-24(17-21)20-25(29(33)36-27)19-23(28(32)30-34)9-5-7-22-8-6-10-26(18-22)35-16-15-31-13-3-2-4-14-31/h6,8,10-12,17-18,20,23,34H,2-5,7,9,13-16,19H2,1H3,(H,30,32) RSUMJYYMCXRSNU-UHFFFAOYSA-N 50332476 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-5-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-pentanoic acid hydroxyamide::CHEMBL1630106 Disintegrin and metalloproteinase domain-containing protein 17 0.270000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332476&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986873 125082578 CHEMBL1630106 ZINC34853100 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169345 Cc1ccc2oc(=O)c(CC(Cc3cccc(OCCN4CCCCC4)c3)C(=O)NO)cc2c1 InChI=1S/C27H32N2O5/c1-19-8-9-25-21(14-19)17-23(27(31)34-25)18-22(26(30)28-32)15-20-6-5-7-24(16-20)33-13-12-29-10-3-2-4-11-29/h5-9,14,16-17,22,32H,2-4,10-13,15,18H2,1H3,(H,28,30) IJISOXVPVQWLAY-UHFFFAOYSA-N 50332472 3-(6-Methyl-2-oxo-2H-chromen-3-yl)-2-(3-(2-(piperidin-1-yl)ethoxy)benzyl)propanoic acid hydroxyamide::CHEMBL1630102 Disintegrin and metalloproteinase domain-containing protein 17 260 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986703 125082574 CHEMBL1630102 ZINC34852705 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169346 Cc1ccc2oc(=O)c(CC(Cc3ccc(OCCN4CCCCC4)cc3)C(=O)NO)cc2c1 InChI=1S/C27H32N2O5/c1-19-5-10-25-21(15-19)17-23(27(31)34-25)18-22(26(30)28-32)16-20-6-8-24(9-7-20)33-14-13-29-11-3-2-4-12-29/h5-10,15,17,22,32H,2-4,11-14,16,18H2,1H3,(H,28,30) ARCRXGOGDAPKEY-UHFFFAOYSA-N 50332471 3-(6-Methyl-2-oxo-2H-chromen-3-yl)-2-(4-(2-(piperidin-1-yl)ethoxy)benzyl)propanoic acid hydroxyamide::CHEMBL1630101 Disintegrin and metalloproteinase domain-containing protein 17 1500 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332471&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986512 125082573 CHEMBL1630101 ZINC34852263 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169347 CCN(CC)CCOc1ccc(CCC(Cc2cc3ccc(C)cc3oc2=O)C(=O)NO)cc1 InChI=1S/C27H34N2O5/c1-4-29(5-2)14-15-33-24-12-8-20(9-13-24)7-11-22(26(30)28-32)18-23-17-21-10-6-19(3)16-25(21)34-27(23)31/h6,8-10,12-13,16-17,22,32H,4-5,7,11,14-15,18H2,1-3H3,(H,28,30) UNOIUBNRWWBQDJ-UHFFFAOYSA-N 50332480 4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-2-oxo-2H-chromen-3-yl)methyl)-butanoic acid hydroxyamide::CHEMBL1630091 Disintegrin and metalloproteinase domain-containing protein 17 60 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332480&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986261 125082582 CHEMBL1630091 ZINC34851725 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169348 Cc1ccc2oc(=O)c(CC(CCc3ccc(O)cc3)C(=O)NO)cc2c1 InChI=1S/C21H21NO5/c1-13-2-9-19-16(10-13)12-17(21(25)27-19)11-15(20(24)22-26)6-3-14-4-7-18(23)8-5-14/h2,4-5,7-10,12,15,23,26H,3,6,11H2,1H3,(H,22,24) OKJLVTXXSSQVIG-UHFFFAOYSA-N 50332470 CHEMBL1630100::N-Hydroxy-4-(4-hydroxyphenyl)-2-((6-methyl-2-oxo-2H-chromen-3-yl)methyl)butan-amide Disintegrin and metalloproteinase domain-containing protein 17 920 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332470&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986115 125082572 CHEMBL1630100 ZINC34851466 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169349 CCN(CC)CCOc1ccc(CCC(Cc2cc3ccc(F)cc3oc2=O)C(=O)NO)cc1 InChI=1S/C26H31FN2O5/c1-3-29(4-2)13-14-33-23-11-6-18(7-12-23)5-8-20(25(30)28-32)16-21-15-19-9-10-22(27)17-24(19)34-26(21)31/h6-7,9-12,15,17,20,32H,3-5,8,13-14,16H2,1-2H3,(H,28,30) FESDJRXXBUYBLT-UHFFFAOYSA-N 50332479 4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-fluoro-2-oxo-2H-chromen-3-yl)methyl)-butanoic acid hydroxyamide::CHEMBL1630090 Disintegrin and metalloproteinase domain-containing protein 17 70 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332479&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53320636 125082581 CHEMBL1630090 ZINC66252832 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169350 Cc1ccc2oc(=O)c(CC(CCCCc3ccccc3)C(=O)NO)cc2c1 InChI=1S/C23H25NO4/c1-16-11-12-21-19(13-16)15-20(23(26)28-21)14-18(22(25)24-27)10-6-5-9-17-7-3-2-4-8-17/h2-4,7-8,11-13,15,18,27H,5-6,9-10,14H2,1H3,(H,24,25) OORDDBSQINIMJU-UHFFFAOYSA-N 50332482 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-6-phenylhexanoicacid hydroxyamide::CHEMBL1630099 Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332482&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986108 125082584 CHEMBL1630099 ZINC34851448 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50169351 CCN(CC)CCOc1ccc(CCC(Cc2cc3cc(C)ccc3oc2=O)C(=O)NO)cc1 InChI=1S/C27H34N2O5/c1-4-29(5-2)14-15-33-24-11-8-20(9-12-24)7-10-21(26(30)28-32)17-23-18-22-16-19(3)6-13-25(22)34-27(23)31/h6,8-9,11-13,16,18,21,32H,4-5,7,10,14-15,17H2,1-3H3,(H,28,30) QJCRHWHXKZBHCY-UHFFFAOYSA-N 50332478 4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((6-methyl-2-oxo-2H-chromen-3-yl)-methyl)-butanoic acid hydroxyamide::CHEMBL1630089 Disintegrin and metalloproteinase domain-containing protein 17 140 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332478&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986257 125082580 CHEMBL1630089 ZINC34851713 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172585 CCCNc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C25H32N6O4S/c1-3-11-26-25-29-19(15-36-25)20-6-4-13-30(20)24(35)22(33)21(32)23(34)28-16(2)17-7-9-18(10-8-17)31-14-5-12-27-31/h5,7-10,12,14-16,20-22,32-33H,3-4,6,11,13H2,1-2H3,(H,26,29)(H,28,34)/t16-,20-,21-,22-/m1/s1 OJMXNABFAINMBJ-XUFNMVPLSA-N 50342943 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-oxo-4-((R)-2-(2-(propylamino)thiazol-4-yl)pyrrolidin-1-yl)butanamide::CHEMBL1770647 Disintegrin and metalloproteinase domain-containing protein 17 4481 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342943&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233013 131345879 CHEMBL1770647 ZINC71332309 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172586 CNc1nc(cs1)[C@H]1CC(F)(F)CN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C23H26F2N6O4S/c1-13(14-4-6-15(7-5-14)31-9-3-8-27-31)28-20(34)18(32)19(33)21(35)30-12-23(24,25)10-17(30)16-11-36-22(26-2)29-16/h3-9,11,13,17-19,32-33H,10,12H2,1-2H3,(H,26,29)(H,28,34)/t13-,17-,18-,19-/m1/s1 ZFHLPUYUQKYDTJ-BYNBJNPRSA-N 50342956 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-4,4-difluoro-2-(2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770822 Disintegrin and metalloproteinase domain-containing protein 17 2769 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581924 131345892 CHEMBL1770822 ZINC71341916 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172587 CNc1nc(cs1)[C@H]1C=CCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C23H26N6O4S/c1-14(15-6-8-16(9-7-15)29-12-4-10-25-29)26-21(32)19(30)20(31)22(33)28-11-3-5-18(28)17-13-34-23(24-2)27-17/h3-10,12-14,18-20,30-31H,11H2,1-2H3,(H,24,27)(H,26,32)/t14-,18-,19-,20-/m1/s1 FHKSWOLIQBUJCL-LMFCIFFHSA-N 50342957 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(methylamino)thiazol-4-yl)-2,5-dihydro-1H-pyrrol-1-yl)-4-oxobutanamide::CHEMBL1770823 Disintegrin and metalloproteinase domain-containing protein 17 1338 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582835 131345893 CHEMBL1770823 ZINC71405081 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172589 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(NC2CC2)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C25H30N6O4S/c1-15(16-5-9-18(10-6-16)31-13-3-11-26-31)27-23(34)21(32)22(33)24(35)30-12-2-4-20(30)19-14-36-25(29-19)28-17-7-8-17/h3,5-6,9-11,13-15,17,20-22,32-33H,2,4,7-8,12H2,1H3,(H,27,34)(H,28,29)/t15-,20-,21-,22-/m1/s1 PRUCBZGVKSTGBL-FPHUIIFBSA-N 50342945 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(cyclopropylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770649 Disintegrin and metalloproteinase domain-containing protein 17 3016 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342945&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233015 131345881 CHEMBL1770649 ZINC71331693 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172590 CNc1nc(cs1)C1(C)CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H30N6O4S/c1-15(16-6-8-17(9-7-16)30-13-5-11-26-30)27-21(33)19(31)20(32)22(34)29-12-4-10-24(29,2)18-14-35-23(25-3)28-18/h5-9,11,13-15,19-20,31-32H,4,10,12H2,1-3H3,(H,25,28)(H,27,33)/t15-,19-,20-,24?/m1/s1 UVUCYVLTGAIXNQ-MQWYCCBPSA-N 50342954 CHEMBL1770820::Rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-(2-methyl-2-(2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 13811 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342954&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583850 131345890 CHEMBL1770820 ZINC71341235 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172592 CC(C)Nc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C25H32N6O4S/c1-15(2)27-25-29-19(14-36-25)20-6-4-12-30(20)24(35)22(33)21(32)23(34)28-16(3)17-7-9-18(10-8-17)31-13-5-11-26-31/h5,7-11,13-16,20-22,32-33H,4,6,12H2,1-3H3,(H,27,29)(H,28,34)/t16-,20-,21-,22-/m1/s1 SLXFUJBJUAFMPC-XUFNMVPLSA-N 50342944 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(isopropylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770648 Disintegrin and metalloproteinase domain-containing protein 17 6677 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342944&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233014 131345880 CHEMBL1770648 ZINC71341956 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172593 CCNc1nc(cs1)[C@H]1C[C@@H](C)CN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C25H32N6O4S/c1-4-26-25-29-19(14-36-25)20-12-15(2)13-30(20)24(35)22(33)21(32)23(34)28-16(3)17-6-8-18(9-7-17)31-11-5-10-27-31/h5-11,14-16,20-22,32-33H,4,12-13H2,1-3H3,(H,26,29)(H,28,34)/t15-,16-,20-,21-,22-/m1/s1 SCBKQDHXBDGKCY-ZMWUJFKZSA-N 50342955 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((2R,4R)-2-(2-(ethylamino)thiazol-4-yl)-4-methylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770821 Disintegrin and metalloproteinase domain-containing protein 17 4040 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342955&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581923 131345891 CHEMBL1770821 ZINC71341526 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172594 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)-c1ccc(F)cc1 InChI=1S/C29H31FN6O4S/c1-17(18-8-12-21(13-9-18)36-16-4-14-32-36)33-27(39)24(37)25(38)28(40)35-15-3-5-22(35)23-26(41-29(31-2)34-23)19-6-10-20(30)11-7-19/h4,6-14,16-17,22,24-25,37-38H,3,5,15H2,1-2H3,(H,31,34)(H,33,39)/t17-,22-,24-,25-/m1/s1 BBNUOLZUSOKOOD-WOVIWESZSA-N 50342951 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(5-(4-fluorophenyl)-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770818 Disintegrin and metalloproteinase domain-containing protein 17 3245 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342951&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582833 131345887 CHEMBL1770818 ZINC71341657 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172595 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)C#N InChI=1S/C24H27N7O4S/c1-14(15-6-8-16(9-7-15)31-12-4-10-27-31)28-22(34)20(32)21(33)23(35)30-11-3-5-17(30)19-18(13-25)36-24(26-2)29-19/h4,6-10,12,14,17,20-21,32-33H,3,5,11H2,1-2H3,(H,26,29)(H,28,34)/t14-,17-,20-,21-/m1/s1 HMIRYGSNGVROMG-HZNDTHDVSA-N 50342952 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(5-cyano-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770819 Disintegrin and metalloproteinase domain-containing protein 17 3036 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342952&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582834 131345888 CHEMBL1770819 ZINC71340485 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172596 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(C)s1 InChI=1S/C24H30N6O4S/c1-14(16-7-9-17(10-8-16)30-13-5-11-26-30)27-22(33)20(31)21(32)23(34)29-12-4-6-18(29)19-15(2)35-24(25-3)28-19/h5,7-11,13-14,18,20-21,31-32H,4,6,12H2,1-3H3,(H,25,28)(H,27,33)/t14-,18-,20-,21-/m1/s1 MPAFFZGRAQCJND-CVDLLHPYSA-N 50342949 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(5-methyl-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770816 Disintegrin and metalloproteinase domain-containing protein 17 2217 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342949&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586736 131345885 CHEMBL1770816 ZINC71341517 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172597 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)C1CC1 InChI=1S/C26H32N6O4S/c1-15(16-8-10-18(11-9-16)32-14-4-12-28-32)29-24(35)21(33)22(34)25(36)31-13-3-5-19(31)20-23(17-6-7-17)37-26(27-2)30-20/h4,8-12,14-15,17,19,21-22,33-34H,3,5-7,13H2,1-2H3,(H,27,30)(H,29,35)/t15-,19-,21-,22-/m1/s1 RBUWEWRCEBYIGA-BDRMCPCVSA-N 50342950 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(5-cyclopropyl-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770817 Disintegrin and metalloproteinase domain-containing protein 17 2574 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342950&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586737 131345886 CHEMBL1770817 ZINC71341453 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172600 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(N)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C22H26N6O4S/c1-13(14-5-7-15(8-6-14)28-11-3-9-24-28)25-20(31)18(29)19(30)21(32)27-10-2-4-17(27)16-12-33-22(23)26-16/h3,5-9,11-13,17-19,29-30H,2,4,10H2,1H3,(H2,23,26)(H,25,31)/t13-,17-,18-,19-/m1/s1 HSIRPRQAXKBTSI-BYNBJNPRSA-N 50342940 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-aminothiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770644 Disintegrin and metalloproteinase domain-containing protein 17 4286 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342940&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586705 131345876 CHEMBL1770644 ZINC71341545 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172601 CCNc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H30N6O4S/c1-3-25-24-28-18(14-35-24)19-6-4-12-29(19)23(34)21(32)20(31)22(33)27-15(2)16-7-9-17(10-8-16)30-13-5-11-26-30/h5,7-11,13-15,19-21,31-32H,3-4,6,12H2,1-2H3,(H,25,28)(H,27,33)/t15-,19-,20-,21-/m1/s1 AZHITYDBWVREAF-NMSZZDKCSA-N 50342942 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(ethylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770646 Disintegrin and metalloproteinase domain-containing protein 17 5107 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53232908 131345878 CHEMBL1770646 ZINC71332298 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172602 CNc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C23H28N6O4S/c1-14(15-6-8-16(9-7-15)29-12-4-10-25-29)26-21(32)19(30)20(31)22(33)28-11-3-5-18(28)17-13-34-23(24-2)27-17/h4,6-10,12-14,18-20,30-31H,3,5,11H2,1-2H3,(H,24,27)(H,26,32)/t14-,18-,19-,20-/m1/s1 XOYUIYPTVVQFBX-LMFCIFFHSA-N 50342941 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770645 Disintegrin and metalloproteinase domain-containing protein 17 5799 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342941&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53232907 131345877 CHEMBL1770645 ZINC71418524 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172603 CNc1nc(cs1)[C@@H]1N(Cc2ccccc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C27H28N6O4S/c1-16(17-8-10-19(11-9-17)33-13-5-12-29-33)30-25(36)23(34)24(35)26(37)32-14-18-6-3-4-7-20(18)22(32)21-15-38-27(28-2)31-21/h3-13,15-16,22-24,34-35H,14H2,1-2H3,(H,28,31)(H,30,36)/t16-,22-,23-,24-/m1/s1 LOTUNSOIIWVNBG-JUJUEEDWSA-N 50342959 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-1-(2-(methylamino)thiazol-4-yl)isoindolin-2-yl)-4-oxobutanamide::CHEMBL1770826 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342959&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587769 131345895 CHEMBL1770826 ZINC43101626 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172605 CNc1nc(cs1)[C@@H]1N(Cc2ccc(F)cc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C27H27FN6O4S/c1-15(16-5-8-19(9-6-16)34-11-3-10-30-34)31-25(37)23(35)24(36)26(38)33-13-17-4-7-18(28)12-20(17)22(33)21-14-39-27(29-2)32-21/h3-12,14-15,22-24,35-36H,13H2,1-2H3,(H,29,32)(H,31,37)/t15-,22-,23-,24-/m1/s1 BPGLVRHHHRCXIG-DVSNZQAGSA-N 50342960 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-6-fluoro-1-(2-(methylamino)thiazol-4-yl)isoindolin-2-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770827 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342960&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54585754 131345896 CHEMBL1770827 ZINC71341474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172606 CNc1nc(cs1)[C@@H]1N(Cc2cc(F)ccc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C27H27FN6O4S/c1-15(16-4-7-19(8-5-16)34-11-3-10-30-34)31-25(37)23(35)24(36)26(38)33-13-17-12-18(28)6-9-20(17)22(33)21-14-39-27(29-2)32-21/h3-12,14-15,22-24,35-36H,13H2,1-2H3,(H,29,32)(H,31,37)/t15-,22-,23-,24-/m1/s1 WFIQWYDIJVTQMA-DVSNZQAGSA-N 50342961 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-5-fluoro-1-(2-(methylamino)thiazol-4-yl)isoindolin-2-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770828 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586738 131345897 CHEMBL1770828 ZINC71340427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172607 CCNc1nc(cs1)[C@@H]1N(Cc2nc(N)ncc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C26H29N9O4S/c1-3-28-26-33-19(13-40-26)20-17-11-29-25(27)32-18(17)12-34(20)24(39)22(37)21(36)23(38)31-14(2)15-5-7-16(8-6-15)35-10-4-9-30-35/h4-11,13-14,20-22,36-37H,3,12H2,1-2H3,(H,28,33)(H,31,38)(H2,27,29,32)/t14-,20-,21-,22-/m1/s1 XQIHPCLYRSFCFS-ISQWPPNESA-N 50342962 (2R,3R)-4-((R)-2-amino-5-(2-(ethylamino)thiazol-4-yl)-5H-pyrrolo[3,4-d]pyrimidin-6(7H)-yl)-N-((R)-1-(4-(cyclopenta-2,4-dienyl)phenyl)ethyl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770829 Disintegrin and metalloproteinase domain-containing protein 17 0.500000 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342962&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233128 131345898 CHEMBL1770829 ZINC71340487 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172609 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)S(C)(=O)=O InChI=1S/C24H30N6O6S2/c1-14(15-7-9-16(10-8-15)30-13-5-11-26-30)27-21(33)19(31)20(32)22(34)29-12-4-6-17(29)18-23(38(3,35)36)37-24(25-2)28-18/h5,7-11,13-14,17,19-20,31-32H,4,6,12H2,1-3H3,(H,25,28)(H,27,33)/t14-,17-,19-,20-/m1/s1 QFHBCQAIZQPRLF-SJFSSXKUSA-N 50342953 (2R,3R)-2,3-dihydroxy-4-{(2R)-2-[2-(methylamino)-5-(methylsulfonyl)-1,3-thiazol-4-yl]pyrrolidin-1-yl}-4-oxo-N-{(1R)-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}butanamide::(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(methylamino)-5-(methylsulfonyl)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1738754 Disintegrin and metalloproteinase domain-containing protein 17 720 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342953&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 786 3O64 51035425 131345889 CHEMBL1738754 ZINC43101616 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172610 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(Nc2ccccc2F)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C28H29FN6O4S/c1-17(18-9-11-19(12-10-18)35-15-5-13-30-35)31-26(38)24(36)25(37)27(39)34-14-4-8-23(34)22-16-40-28(33-22)32-21-7-3-2-6-20(21)29/h2-3,5-7,9-13,15-17,23-25,36-37H,4,8,14H2,1H3,(H,31,38)(H,32,33)/t17-,23-,24-,25-/m1/s1 QRDIQZQQVWIMMN-LRGWBYFTSA-N 50342947 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(2-fluorophenylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770651 Disintegrin and metalloproteinase domain-containing protein 17 1143 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587745 131345883 CHEMBL1770651 ZINC71341708 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172611 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(NC2CCC2)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C26H32N6O4S/c1-16(17-8-10-19(11-9-17)32-14-4-12-27-32)28-24(35)22(33)23(34)25(36)31-13-3-7-21(31)20-15-37-26(30-20)29-18-5-2-6-18/h4,8-12,14-16,18,21-23,33-34H,2-3,5-7,13H2,1H3,(H,28,35)(H,29,30)/t16-,21-,22-,23-/m1/s1 RIKDCTFOLNLMSX-HKDUHGGJSA-N 50342946 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(cyclobutylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770650 Disintegrin and metalloproteinase domain-containing protein 17 2153 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342946&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233016 131345882 CHEMBL1770650 ZINC71341271 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172612 CNc1nc(cs1)[C@H]1C[C@H]2C[C@H]2N1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H28N6O4S/c1-13(14-4-6-16(7-5-14)29-9-3-8-26-29)27-22(33)20(31)21(32)23(34)30-18-10-15(18)11-19(30)17-12-35-24(25-2)28-17/h3-9,12-13,15,18-21,31-32H,10-11H2,1-2H3,(H,25,28)(H,27,33)/t13-,15-,18-,19-,20-,21-/m1/s1 MGJFSYHPCJKUCF-BMSGLIPJSA-N 50342958 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((1R,3R,5R)-3-(2-(methylamino)thiazol-4-yl)-2-azabicyclo[3.1.0]hexan-2-yl)-4-oxobutanamide::CHEMBL1770824 Disintegrin and metalloproteinase domain-containing protein 17 707 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342958&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582836 131345894 CHEMBL1770824 ZINC71341768 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50172613 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(Nc2cccnc2)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C27H29N7O4S/c1-17(18-7-9-20(10-8-18)34-14-4-12-29-34)30-25(37)23(35)24(36)26(38)33-13-3-6-22(33)21-16-39-27(32-21)31-19-5-2-11-28-15-19/h2,4-5,7-12,14-17,22-24,35-36H,3,6,13H2,1H3,(H,30,37)(H,31,32)/t17-,22-,23-,24-/m1/s1 ZAHVPBWMKQVFIS-SFUZCSOBSA-N 50342948 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-oxo-4-((R)-2-(2-(pyridin-3-ylamino)thiazol-4-yl)pyrrolidin-1-yl)butanamide::CHEMBL1770652 Disintegrin and metalloproteinase domain-containing protein 17 5552 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342948&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581886 131345884 CHEMBL1770652 ZINC71341871 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186964 CC(C)C[C@H]([C@H](C)N(O)C=O)C(=O)N[C@@H](CC(C)(C)C)C(=O)Nc1nccs1 InChI=1S/C19H32N4O4S/c1-12(2)9-14(13(3)23(27)11-24)16(25)21-15(10-19(4,5)6)17(26)22-18-20-7-8-28-18/h7-8,11-15,27H,9-10H2,1-6H3,(H,21,25)(H,20,22,26)/t13-,14+,15-/m0/s1 VPADZEAGMFRILI-ZNMIVQPWSA-N 50103094 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid [3,3-dimethyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL68812 Disintegrin and metalloproteinase domain-containing protein 17 64 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103094 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103094&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308295 103999441 CHEMBL68812 ZINC26274434 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186967 CC[C@@H]([C@@H](CC(C)C)C(=O)N[C@H](C(=O)Nc1ccccn1)C(C)(C)C)N(O)C=O InChI=1S/C21H34N4O4/c1-7-16(25(29)13-26)15(12-14(2)3)19(27)24-18(21(4,5)6)20(28)23-17-10-8-9-11-22-17/h8-11,13-16,18,29H,7,12H2,1-6H3,(H,24,27)(H,22,23,28)/t15-,16+,18-/m1/s1 CVMOEYXHQALNTG-SOLBZPMBSA-N 50103095 (2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentanoic acid [2,2-dimethyl-1-(pyridin-2-ylcarbamoyl)-propyl]-amide::CHEMBL307773 Disintegrin and metalloproteinase domain-containing protein 17 29 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103095 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103095&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308327 103999442 CHEMBL307773 ZINC26252502 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186969 CC[C@@H]([C@@H](CC(C)C)C(=O)N[C@H](C(=O)Nc1nccs1)C(C)(C)C)N(O)C=O InChI=1S/C19H32N4O4S/c1-7-14(23(27)11-24)13(10-12(2)3)16(25)21-15(19(4,5)6)17(26)22-18-20-8-9-28-18/h8-9,11-15,27H,7,10H2,1-6H3,(H,21,25)(H,20,22,26)/t13-,14+,15-/m1/s1 BGNATPVKWHRROW-QLFBSQMISA-N 50103097 (2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentanoic acid [2,2-dimethyl-1-(thiazol-2-ylcarbamoyl)-propyl]-amide::CHEMBL304295 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103097 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103097&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308525 103999444 CHEMBL304295 ZINC26261207 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186973 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)CC(=O)NO)C(C)(C)C InChI=1S/C15H29N3O4/c1-9(2)7-10(8-11(19)18-22)13(20)17-12(14(21)16-6)15(3,4)5/h9-10,12,22H,7-8H2,1-6H3,(H,16,21)(H,17,20)(H,18,19)/t10-,12-/m1/s1 QRXOZHSEEGNRFC-ZYHUDNBSSA-N 50063920 (R)-N*1*-((S)-2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*4*-hydroxy-2-isobutyl-succinamide::(R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::CHEMBL16520::Ro-31-9790 Disintegrin and metalloproteinase domain-containing protein 17 87 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063920&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9904965 103959092 CHEMBL16520 ZINC01534591 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186975 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](C)N(O)C=O)C(C)(C)C InChI=1S/C16H31N3O4/c1-10(2)8-12(11(3)19(23)9-20)14(21)18-13(15(22)17-7)16(4,5)6/h9-13,23H,8H2,1-7H3,(H,17,22)(H,18,21)/t11-,12+,13+/m0/s1 RGDBGIBFYROBCD-YNEHKIRRSA-N 50103092 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid (2,2-dimethyl-1-methylcarbamoyl-propyl)-amide::CHEMBL66970 Disintegrin and metalloproteinase domain-containing protein 17 142 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103092 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103092&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308377 103999439 CHEMBL66970 ZINC26251250 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186984 CC(C)C[C@H]([C@H](C)N(O)C=O)C(=O)N[C@H](C(=O)Nc1nccs1)C(C)(C)C InChI=1S/C18H30N4O4S/c1-11(2)9-13(12(3)22(26)10-23)15(24)20-14(18(4,5)6)16(25)21-17-19-7-8-27-17/h7-8,10-14,26H,9H2,1-6H3,(H,20,24)(H,19,21,25)/t12-,13+,14+/m0/s1 AHCJFAZGYUITPV-BFHYXJOUSA-N 50103098 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid [2,2-dimethyl-1-(thiazol-2-ylcarbamoyl)-propyl]-amide::CHEMBL68553 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103098 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103098&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308640 103999445 CHEMBL68553 ZINC03820358 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186989 CCC(C)[C@H](NC(=O)[C@H](CC(C)C)[C@H](CC)N(O)C=O)C(=O)Nc1ccccn1 InChI=1S/C21H34N4O4/c1-6-15(5)19(21(28)23-18-10-8-9-11-22-18)24-20(27)16(12-14(3)4)17(7-2)25(29)13-26/h8-11,13-17,19,29H,6-7,12H2,1-5H3,(H,24,27)(H,22,23,28)/t15?,16-,17+,19+/m1/s1 YPFZRQMUNBCBEG-YEBPUJJMSA-N 50103101 (2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentanoic acid [(S)-2-methyl-1-(pyridin-2-ylcarbamoyl)-butyl]-amide::CHEMBL68667 Disintegrin and metalloproteinase domain-containing protein 17 31 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103101 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103101&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308623 103999448 CHEMBL68667 ZINC26272992 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186992 CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)[C@H](CC)N(O)C=O)C(=O)Nc1nccs1 InChI=1S/C19H32N4O4S/c1-6-13(5)16(18(26)22-19-20-8-9-28-19)21-17(25)14(10-12(3)4)15(7-2)23(27)11-24/h8-9,11-16,27H,6-7,10H2,1-5H3,(H,21,25)(H,20,22,26)/t13-,14+,15-,16-/m0/s1 IQHWFMFCBUDMAF-FZKCQIBNSA-N 50103099 (2R,3S)-3-(Formyl-hydroxy-amino)-2-isobutyl-pentanoic acid [(S)-2-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL69596 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103099 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103099&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308624 103999446 CHEMBL69596 ZINC26270803 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186994 CC(C)C[C@H]([C@H](C)N(O)C=O)C(=O)N[C@H](C(N)=O)C(C)(C)C InChI=1S/C15H29N3O4/c1-9(2)7-11(10(3)18(22)8-19)14(21)17-12(13(16)20)15(4,5)6/h8-12,22H,7H2,1-6H3,(H2,16,20)(H,17,21)/t10-,11+,12+/m0/s1 ZWYFAUSBUXUGKC-QJPTWQEYSA-N 50103100 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid (1-carbamoyl-2,2-dimethyl-propyl)-amide::CHEMBL66098 Disintegrin and metalloproteinase domain-containing protein 17 156 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103100 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103100&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308488 103999447 CHEMBL66098 ZINC26259776 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50186997 CC(C)C[C@H]([C@H](C)N(O)C=O)C(=O)N[C@@H](C(C)C)C(=O)Nc1nccs1 InChI=1S/C17H28N4O4S/c1-10(2)8-13(12(5)21(25)9-22)15(23)19-14(11(3)4)16(24)20-17-18-6-7-26-17/h6-7,9-14,25H,8H2,1-5H3,(H,19,23)(H,18,20,24)/t12-,13+,14-/m0/s1 NCKDXXIBASBEEV-MJBXVCDLSA-N 50103102 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid [2-methyl-1-(thiazol-2-ylcarbamoyl)-propyl]-amide::CHEMBL302941 Disintegrin and metalloproteinase domain-containing protein 17 27 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103102 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103102&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308297 103999449 CHEMBL302941 ZINC26273521 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50187001 CC(C)C[C@H](NC(=O)[C@H](CC(C)C)[C@H](C)N(O)C=O)C(=O)Nc1nccs1 InChI=1S/C18H30N4O4S/c1-11(2)8-14(13(5)22(26)10-23)16(24)20-15(9-12(3)4)17(25)21-18-19-6-7-27-18/h6-7,10-15,26H,8-9H2,1-5H3,(H,20,24)(H,19,21,25)/t13-,14+,15-/m0/s1 WEQCLTHHZZNFDV-ZNMIVQPWSA-N 50103096 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid [3-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL66181 Disintegrin and metalloproteinase domain-containing protein 17 55 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103096 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103096&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308304 103999443 CHEMBL66181 ZINC26263104 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50187002 CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)[C@H](C)N(O)C=O)C(=O)Nc1nccs1 InChI=1S/C18H30N4O4S/c1-6-12(4)15(17(25)21-18-19-7-8-27-18)20-16(24)14(9-11(2)3)13(5)22(26)10-23/h7-8,10-15,26H,6,9H2,1-5H3,(H,20,24)(H,19,21,25)/t12-,13-,14+,15-/m0/s1 UWHDYIJAXRNLQS-XQLPTFJDSA-N 50103093 (R)-2-[(S)-1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid [(R)-2-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL69418 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/s0960-894x(01)00377-8 10.7270/Q2QZ298V 11514157 Musso, DL; Andersen, MW; Andrews, RC; Austin, R; Beaudet, EJ; Becherer, JD; Bubacz, DG; Bickett, DM; Chan, JH; Conway, JG; Cowan, DJ; Gaul, MD; Glennon, KC; Hedeen, KM; Lambert, MH; Leesnitzer, MA; McDougald, DL; Mitchell, JL; Moss, ML; Rabinowitz, MH; Rizzolio, MC; Schaller, LT; Stanford, JB; Tippin, T; Warner, JR; Whitesell, LG; Wiethe, RW GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103093 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103093&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44308298 103999440 CHEMBL69418 ZINC26273566 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193360 CC(C)C[C@H]([C@H](C)N(O)C=O)C(=O)N[C@@H]([C@H](C)CCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1 InChI=1S/C19H32N8O6S/c1-11(2)9-14(13(4)26(31)10-28)16(29)23-15(17(30)24-19-22-7-8-34-19)12(3)5-6-21-18(20)25-27(32)33/h7-8,10-15,31H,5-6,9H2,1-4H3,(H,23,29)(H3,20,21,25)(H,22,24,30)/t12-,13+,14-,15+/m1/s1 HUBNMJYLBBXLHV-BARDWOONSA-N 50106668 (2R,3R)-N-{(1R)-4-Nitroguanyl-2-[((2R)-2-{(1S)-1-[formyl(hydroxy)amino]ethyl}-4-methylpentanoyl)amino]-3-methyl-N-1,3-thiazol-2-yl)pentanamide::CHEMBL135590 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106668&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10983916 104002149 CHEMBL135590 ZINC13470359 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193368 CC(C)C[C@H]([C@H](C)N(O)C=O)C(=O)N[C@@H]([C@H](C)CCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1 InChI=1S/C20H35N7O6S2/c1-12(2)10-15(14(4)27(31)11-28)17(29)24-16(18(30)25-20-23-8-9-34-20)13(3)6-7-22-19(21)26-35(5,32)33/h8-9,11-16,31H,6-7,10H2,1-5H3,(H,24,29)(H3,21,22,26)(H,23,25,30)/t13-,14+,15-,16+/m1/s1 QUEIBYWBRFSDLX-QXSJWSMHSA-N 50106654 2-[1-(Formyl-hydroxy-amino)-ethyl]-4-methyl-pentanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-2-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL135783 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106654&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10864417 104002135 CHEMBL135783 ZINC27427205 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193379 CCC[C@@H]([C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C24H40N8O6S/c1-3-5-20(31(36)15-33)18(14-17-9-7-16(2)8-10-17)21(34)28-19(22(35)29-24-27-12-13-39-24)6-4-11-26-23(25)30-32(37)38/h12-13,15-20,36H,3-11,14H2,1-2H3,(H,28,34)(H3,25,26,30)(H,27,29,35)/t16?,17?,18-,19+,20+/m1/s1 LAQQWJARJKOYJJ-PBDJWPIDSA-N 50106670 (2R,3R)-N-{(1R)-4-Nitroguanyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-3-[formyl(hydroxy)amino]-2-[(4-cyclohexylmethyl)methyl]-hexanamide::CHEMBL335009 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106670&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11017232 104002151 CHEMBL335009 ZINC03923978 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193381 CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)NS(=O)(=O)c1ccccn1)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C25H38N8O6S2/c1-4-8-20(33(37)16-34)18(15-17(2)3)22(35)30-19(23(36)31-25-29-13-14-40-25)9-7-12-28-24(26)32-41(38,39)21-10-5-6-11-27-21/h5-6,10-11,13-14,16-20,37H,4,7-9,12,15H2,1-3H3,(H,30,35)(H3,26,28,32)(H,29,31,36)/t18-,19+,20+/m1/s1 JERYKMOBMXUTFQ-AABGKKOBSA-N 50106667 3-(Formyl-hydroxy-amino)-2-isobutyl-hexanoic acid [4-{[amino-(pyridine-2-sulfonylimino)-methyl]-amino}-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL133369 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106667&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10886607 104002148 CHEMBL133369 ZINC27426719 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193382 CC(C)C[C@H]([C@H](CCC(F)(F)F)N(O)C=O)C(=O)N[C@@H]([C@H](C)CCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1 InChI=1S/C22H36F3N7O6S2/c1-13(2)11-15(16(32(36)12-33)5-7-22(23,24)25)18(34)29-17(19(35)30-21-28-9-10-39-21)14(3)6-8-27-20(26)31-40(4,37)38/h9-10,12-17,36H,5-8,11H2,1-4H3,(H,29,34)(H3,26,27,31)(H,28,30,35)/t14-,15-,16+,17+/m1/s1 KIKBZIXCMWKZEI-NCOADZHNSA-N 50106663 6,6,6-Trifluoro-3-(formyl-hydroxy-amino)-2-isobutyl-hexanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-2-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL334567 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106663&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11124943 104002144 CHEMBL334567 ZINC27420801 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193385 CC(C)[C@@H]([C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](CCCN=C(N)NS(=O)(=O)c1ccccn1)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C29H44N8O6S2/c1-19(2)25(37(41)18-38)22(17-21-11-9-20(3)10-12-21)26(39)34-23(27(40)35-29-33-15-16-44-29)7-6-14-32-28(30)36-45(42,43)24-8-4-5-13-31-24/h4-5,8,13,15-16,18-23,25,41H,6-7,9-12,14,17H2,1-3H3,(H,34,39)(H3,30,32,36)(H,33,35,40)/t20?,21?,22-,23+,25+/m1/s1 UBBKFTZMBAKVDC-OSBIAPMOSA-N 50106662 3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cyclohexylmethyl)-pentanoic acid [4-{[amino-(pyridine-2-sulfonylimino)-methyl]-amino}-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL135983 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106662 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106662&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11072397 104002143 CHEMBL135983 ZINC27428442 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193387 CCC[C@@H]([C@@H](Cc1ccc(C)s1)C(=O)N[C@@H](CCCN=C(N)NS(=O)(=O)c1ccccn1)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C27H36N8O6S3/c1-3-7-22(35(39)17-36)20(16-19-11-10-18(2)43-19)24(37)32-21(25(38)33-27-31-14-15-42-27)8-6-13-30-26(28)34-44(40,41)23-9-4-5-12-29-23/h4-5,9-12,14-15,17,20-22,39H,3,6-8,13,16H2,1-2H3,(H,32,37)(H3,28,30,34)(H,31,33,38)/t20-,21+,22+/m1/s1 VUYBRUBUOZYSQS-FSSWDIPSSA-N 50106671 3-(Formyl-hydroxy-amino)-2-isobutyl-hexanoic acid [4-{[amino-(pyridine-2-sulfonylimino)-methyl]-amino}-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL133314 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106671&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10985227 104002152 CHEMBL133314 ZINC27426724 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193388 CC(C)C[C@H]([C@H](C(C)C)N(O)C=O)C(=O)N[C@@H](CCCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1 InChI=1S/C21H37N7O6S2/c1-13(2)11-15(17(14(3)4)28(32)12-29)18(30)25-16(19(31)26-21-24-9-10-35-21)7-6-8-23-20(22)27-36(5,33)34/h9-10,12-17,32H,6-8,11H2,1-5H3,(H,25,30)(H3,22,23,27)(H,24,26,31)/t15-,16+,17+/m1/s1 YBQLENDMILTZBB-IKGGRYGDSA-N 50106665 3-(Formyl-hydroxy-amino)-2-isobutyl-4-methyl-pentanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL135886 Disintegrin and metalloproteinase domain-containing protein 17 42 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106665&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10907725 104002146 CHEMBL135886 ZINC27427012 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50198793 ONC(=O)C1Cc2ccccc2CN1 InChI=1S/C10H12N2O2/c13-10(12-14)9-5-7-3-1-2-4-8(7)6-11-9/h1-4,9,11,14H,5-6H2,(H,12,13) IAGAVMMBKLNEPN-UHFFFAOYSA-N 50109641 1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic acid hydroxyamide::CHEMBL425844 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109641&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384659 104004581 CHEMBL425844 ZINC13472507 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204789 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2-c2ccccc2)cc1 InChI=1S/C25H26N2O6S/c28-20-14-15-27(24(16-20)25(29)26-30)34(31,32)22-12-10-21(11-13-22)33-17-19-8-4-5-9-23(19)18-6-2-1-3-7-18/h1-13,20,24,28,30H,14-17H2,(H,26,29)/t20-,24+/m0/s1 HLNRKJGRBAIQKZ-GBXCKJPGSA-N 50113020 (2R,4S)-1-[4-(Biphenyl-2-ylmethoxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL282094 Disintegrin and metalloproteinase domain-containing protein 17 67 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113020&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278511 104007371 CHEMBL282094 ZINC13441634 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204792 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(c2)C#N)cc1 InChI=1S/C20H21N3O6S/c21-12-14-2-1-3-15(10-14)13-29-17-4-6-18(7-5-17)30(27,28)23-9-8-16(24)11-19(23)20(25)22-26/h1-7,10,16,19,24,26H,8-9,11,13H2,(H,22,25)/t16-,19+/m0/s1 ZPGDUPIWHDBXOW-QFBILLFUSA-N 50113021 (2R,4S)-1-[4-(3-Cyano-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29217 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278512 104007372 CHEMBL29217 ZINC13441632 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204794 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc(c2)C#N)cc1 InChI=1S/C20H21N3O6S/c21-11-14-2-1-3-15(10-14)13-29-17-5-7-18(8-6-17)30(27,28)23-12-16(24)4-9-19(23)20(25)22-26/h1-3,5-8,10,16,19,24,26H,4,9,12-13H2,(H,22,25)/t16-,19-/m1/s1 VODMHORGCWILKX-VQIMIIECSA-N 50113026 (2R,5R)-1-[4-(3-Cyano-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28678 Disintegrin and metalloproteinase domain-containing protein 17 49 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113026&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278455 104007377 CHEMBL28678 ZINC13441644 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204799 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2C#N)cc1 InChI=1S/C20H21N3O6S/c21-11-14-3-1-2-4-15(14)13-29-17-6-8-18(9-7-17)30(27,28)23-12-16(24)5-10-19(23)20(25)22-26/h1-4,6-9,16,19,24,26H,5,10,12-13H2,(H,22,25)/t16-,19-/m1/s1 PBIRCNBIZATFIL-VQIMIIECSA-N 50113031 (2R,5R)-1-[4-(2-Cyano-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28139 Disintegrin and metalloproteinase domain-containing protein 17 39 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113031&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9802812 104007382 CHEMBL28139 ZINC13441646 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204801 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(Cl)c2)cc1 InChI=1S/C19H21ClN2O6S/c20-14-3-1-2-13(10-14)12-28-16-4-6-17(7-5-16)29(26,27)22-9-8-15(23)11-18(22)19(24)21-25/h1-7,10,15,18,23,25H,8-9,11-12H2,(H,21,24)/t15-,18+/m0/s1 QUHKOMQMEHKSHH-MAUKXSAKSA-N 50113034 (2R,4S)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28942 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113034&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278412 104007385 CHEMBL28942 ZINC13441615 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204802 Cc1ccc(COc2ccc(cc2)S(=O)(=O)N2CC[C@H](O)C[C@@H]2C(=O)NO)cc1 InChI=1S/C20H24N2O6S/c1-14-2-4-15(5-3-14)13-28-17-6-8-18(9-7-17)29(26,27)22-11-10-16(23)12-19(22)20(24)21-25/h2-9,16,19,23,25H,10-13H2,1H3,(H,21,24)/t16-,19+/m0/s1 AKGNGCYABOLSMF-QFBILLFUSA-N 50113030 (2R,4S)-4-Hydroxy-1-[4-(4-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28815 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113030&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910032 104007381 CHEMBL28815 ZINC13441619 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204806 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)14-3-1-13(2-4-14)12-31-16-6-8-17(9-7-16)32(29,30)25-11-15(26)5-10-18(25)19(27)24-28/h1-4,6-9,15,18,26,28H,5,10-12H2,(H,24,27)/t15-,18-/m1/s1 DLEQDRFQHDSZFK-CRAIPNDOSA-N 50113037 (2R,5R)-5-Hydroxy-1-[4-(4-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL282584 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113037&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278523 104007388 CHEMBL282584 ZINC13441638 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202601 CC#CCOc1ccc(cc1)S(=O)(=O)Nc1c(C)cccc1C(=O)NO InChI=1S/C18H18N2O5S/c1-3-4-12-25-14-8-10-15(11-9-14)26(23,24)20-17-13(2)6-5-7-16(17)18(21)19-22/h5-11,20,22H,12H2,1-2H3,(H,19,21) VXXLUYPODYWRKE-UHFFFAOYSA-N 50111701 2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-3-methyl-benzamide::CHEMBL19320 Disintegrin and metalloproteinase domain-containing protein 17 84 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111701&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44272355 104006226 CHEMBL19320 ZINC13440717 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202602 CCCCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C19H23BrN2O5S/c1-4-5-10-27-15-6-8-16(9-7-15)28(25,26)22(3)18-13(2)11-14(20)12-17(18)19(23)21-24/h6-9,11-12,24H,4-5,10H2,1-3H3,(H,21,23) IHKCSGLIRGMLDE-UHFFFAOYSA-N 50111694 5-Bromo-2-[(4-butoxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL273764 Disintegrin and metalloproteinase domain-containing protein 17 67 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111694&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23506779 104006219 CHEMBL273764 ZINC13440696 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202605 COc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C16H17BrN2O5S/c1-10-8-11(17)9-14(16(20)18-21)15(10)19(2)25(22,23)13-6-4-12(24-3)5-7-13/h4-9,21H,1-3H3,(H,18,20) JXCARHJPSZBVFH-UHFFFAOYSA-N 50111695 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-methyl-benzamide::5-bromo-N-hydroxy-2-(4-methoxy-N-methylphenylsulfonamido)-3-methylbenzamide::CHEMBL18614 Disintegrin and metalloproteinase domain-containing protein 17 32 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111695&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23506783 104006220 CHEMBL18614 ZINC13440690 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202607 COCC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C20H21BrN2O6S/c1-14-12-15(21)13-18(20(24)22-25)19(14)23(2)30(26,27)17-8-6-16(7-9-17)29-11-5-4-10-28-3/h6-9,12-13,25H,10-11H2,1-3H3,(H,22,24) FODLAGUBVKDEIZ-UHFFFAOYSA-N 50111702 5-Bromo-N-hydroxy-2-{[4-(4-methoxy-but-2-ynyloxy)-benzenesulfonyl]-methyl-amino}-3-methyl-benzamide::CHEMBL18895 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111702&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9957500 104006227 CHEMBL18895 ZINC13440711 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202609 CCCC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C21H23BrN2O5S/c1-4-5-6-7-12-29-17-8-10-18(11-9-17)30(27,28)24(3)20-15(2)13-16(22)14-19(20)21(25)23-26/h8-11,13-14,26H,4-5,12H2,1-3H3,(H,23,25) MDOGBVLWCBWUMC-UHFFFAOYSA-N 50111700 5-Bromo-2-[(4-hex-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL18649 Disintegrin and metalloproteinase domain-containing protein 17 47 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111700&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9848625 104006225 CHEMBL18649 ZINC13440708 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202611 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cc(cc1C(=O)NO)-c1ccccc1)C1CCN(C)CC1 InChI=1S/C30H33N3O5S/c1-4-5-19-38-25-11-13-26(14-12-25)39(36,37)33(3)29-27(23-15-17-32(2)18-16-23)20-24(21-28(29)30(34)31-35)22-9-7-6-8-10-22/h6-14,20-21,23,35H,15-19H2,1-3H3,(H,31,34) WGPIMMRNIAYWBT-UHFFFAOYSA-N 50111698 4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-5-(1-methyl-piperidin-4-yl)-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL19278 Disintegrin and metalloproteinase domain-containing protein 17 42 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111698&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44272540 104006223 CHEMBL19278 ZINC28223542 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202613 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cc(Br)cc1C(=O)NO)C1CCN(C)CC1 InChI=1S/C24H28BrN3O5S/c1-4-5-14-33-19-6-8-20(9-7-19)34(31,32)28(3)23-21(17-10-12-27(2)13-11-17)15-18(25)16-22(23)24(29)26-30/h6-9,15-17,30H,10-14H2,1-3H3,(H,26,29) JNFDCDGQVIEXPD-UHFFFAOYSA-N 50111703 5-Bromo-2-[(4-but-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-(1-methyl-piperidin-4-yl)-benzamide::CHEMBL18667 Disintegrin and metalloproteinase domain-containing protein 17 25 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111703&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44272353 104006228 CHEMBL18667 ZINC28222186 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202618 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C19H19BrN2O5S/c1-4-5-10-27-15-6-8-16(9-7-15)28(25,26)22(3)18-13(2)11-14(20)12-17(18)19(23)21-24/h6-9,11-12,24H,10H2,1-3H3,(H,21,23) PDBHRMUGMOPNOC-UHFFFAOYSA-N 50111696 5-Bromo-2-[(4-but-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL19005 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111696&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10050222 104006221 CHEMBL19005 ZINC13440694 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202620 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1ccccc1C(=O)NO InChI=1S/C18H18N2O5S/c1-3-4-13-25-14-9-11-15(12-10-14)26(23,24)20(2)17-8-6-5-7-16(17)18(21)19-22/h5-12,22H,13H2,1-2H3,(H,19,21) XNSXZLYFBPIUKQ-UHFFFAOYSA-N 50111706 2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-benzamide::CHEMBL18868 Disintegrin and metalloproteinase domain-containing protein 17 27 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111706&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44272354 104006231 CHEMBL18868 ZINC13440718 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202623 COc1ccc(cc1)S(=O)(=O)N(C)c1c(cc(Br)cc1C(=O)NO)C1CCN(C)CC1 InChI=1S/C21H26BrN3O5S/c1-24-10-8-14(9-11-24)18-12-15(22)13-19(21(26)23-27)20(18)25(2)31(28,29)17-6-4-16(30-3)5-7-17/h4-7,12-14,27H,8-11H2,1-3H3,(H,23,26) ZLSOXSXSNCNKSX-UHFFFAOYSA-N 50111707 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-(1-methyl-piperidin-4-yl)-benzamide::CHEMBL278872 Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111707&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44272475 104006232 CHEMBL278872 ZINC28222067 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202628 CCN(CC)CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C23H28BrN3O5S/c1-5-27(6-2)13-7-8-14-32-19-9-11-20(12-10-19)33(30,31)26(4)22-17(3)15-18(24)16-21(22)23(28)25-29/h9-12,15-16,29H,5-6,13-14H2,1-4H3,(H,25,28) WZCXPYXIESDPBM-UHFFFAOYSA-N 50111708 5-Bromo-2-{[4-(4-diethylamino-but-2-ynyloxy)-benzenesulfonyl]-methyl-amino}-N-hydroxy-3-methyl-benzamide::CHEMBL277206 Disintegrin and metalloproteinase domain-containing protein 17 346 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111708&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9915194 104006233 CHEMBL277206 ZINC28223965 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202629 CCCCC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C22H25BrN2O5S/c1-4-5-6-7-8-13-30-18-9-11-19(12-10-18)31(28,29)25(3)21-16(2)14-17(23)15-20(21)22(26)24-27/h9-12,14-15,27H,4-6,13H2,1-3H3,(H,24,26) UFJYSWCFYDZPKS-UHFFFAOYSA-N 50111697 5-Bromo-2-[(4-hept-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL416173 Disintegrin and metalloproteinase domain-containing protein 17 34 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111697&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9870933 104006222 CHEMBL416173 ZINC13440698 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204809 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc(c2)C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)14-3-1-2-13(10-14)12-31-16-5-7-17(8-6-16)32(29,30)25-11-15(26)4-9-18(25)19(27)24-28/h1-3,5-8,10,15,18,26,28H,4,9,11-12H2,(H,24,27)/t15-,18-/m1/s1 HTWOMTYWAUKKSB-CRAIPNDOSA-N 50113033 (2R,5R)-5-Hydroxy-1-[4-(3-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28351 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113033&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278522 104007384 CHEMBL28351 ZINC13441640 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204810 COC(=O)[C@@H]1CCN([C@H](C1)C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1 InChI=1S/C21H23FN2O7S/c1-30-21(26)15-10-11-24(19(12-15)20(25)23-27)32(28,29)18-8-6-17(7-9-18)31-13-14-2-4-16(22)5-3-14/h2-9,15,19,27H,10-13H2,1H3,(H,23,25)/t15-,19-/m1/s1 LBWSTPFPCOJWNQ-DNVCBOLYSA-N 50113040 (2R,4R)-1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-2-hydroxycarbamoyl-piperidine-4-carboxylic acid methyl ester::CHEMBL283026 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113040&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278377 104007391 CHEMBL283026 ZINC13441658 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204814 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H22N2O6S/c22-15-10-11-21(18(12-15)19(23)20-24)28(25,26)17-8-6-16(7-9-17)27-13-14-4-2-1-3-5-14/h1-9,15,18,22,24H,10-13H2,(H,20,23)/t15-,18+/m0/s1 ACEUKQZDNBIUHG-MAUKXSAKSA-N 50113038 (2R,4S)-1-(4-Benzyloxy-benzenesulfonyl)-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL281920 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113038&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541745 104007389 CHEMBL281920 ZINC13441605 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204817 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccc(Cl)cc2)cc1 InChI=1S/C19H21ClN2O6S/c20-14-3-1-13(2-4-14)12-28-16-5-7-17(8-6-16)29(26,27)22-10-9-15(23)11-18(22)19(24)21-25/h1-8,15,18,23,25H,9-12H2,(H,21,24)/t15-,18+/m0/s1 QYSRKEKGXZIJBG-MAUKXSAKSA-N 50113035 (2R,4S)-1-[4-(4-Chloro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL31776 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113035&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541746 104007386 CHEMBL31776 ZINC13441613 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204820 COC(=O)[C@@H]1CCN([C@H](C1)C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1 InChI=1S/C20H21FN2O7S/c1-29-20(25)13-10-11-23(18(12-13)19(24)22-26)31(27,28)17-8-6-16(7-9-17)30-15-4-2-14(21)3-5-15/h2-9,13,18,26H,10-12H2,1H3,(H,22,24)/t13-,18-/m1/s1 LDMWZYZAAZFUTC-FZKQIMNGSA-N 50113029 (2R,4R)-1-[4-(4-Fluoro-phenoxy)-benzenesulfonyl]-2-hydroxycarbamoyl-piperidine-4-carboxylic acid methyl ester::CHEMBL286772 Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113029&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278576 104007380 CHEMBL286772 ZINC13441656 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204821 COc1cccc(COc2ccc(cc2)S(=O)(=O)N2CC[C@H](O)C[C@@H]2C(=O)NO)c1 InChI=1S/C20H24N2O7S/c1-28-17-4-2-3-14(11-17)13-29-16-5-7-18(8-6-16)30(26,27)22-10-9-15(23)12-19(22)20(24)21-25/h2-8,11,15,19,23,25H,9-10,12-13H2,1H3,(H,21,24)/t15-,19+/m0/s1 HESLKHVXAOLKPX-HNAYVOBHSA-N 50113036 (2R,4S)-4-Hydroxy-1-[4-(3-methoxy-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29211 Disintegrin and metalloproteinase domain-containing protein 17 27 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113036&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278550 104007387 CHEMBL29211 ZINC13441625 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204824 Cc1cccc(COc2ccc(cc2)S(=O)(=O)N2CC[C@H](O)C[C@@H]2C(=O)NO)c1 InChI=1S/C20H24N2O6S/c1-14-3-2-4-15(11-14)13-28-17-5-7-18(8-6-17)29(26,27)22-10-9-16(23)12-19(22)20(24)21-25/h2-8,11,16,19,23,25H,9-10,12-13H2,1H3,(H,21,24)/t16-,19+/m0/s1 HRFNCDYTGOTSMJ-QFBILLFUSA-N 50113023 (2R,4S)-4-Hydroxy-1-[4-(3-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28350 Disintegrin and metalloproteinase domain-containing protein 17 18 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113023&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541748 104007374 CHEMBL28350 ZINC13441621 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204826 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2F)cc1 InChI=1S/C19H21FN2O6S/c20-17-4-2-1-3-13(17)12-28-15-5-7-16(8-6-15)29(26,27)22-10-9-14(23)11-18(22)19(24)21-25/h1-8,14,18,23,25H,9-12H2,(H,21,24)/t14-,18+/m0/s1 MAHFPNFDBUALNZ-KBXCAEBGSA-N 50113032 (2R,4S)-1-[4-(2-Fluoro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28141 Disintegrin and metalloproteinase domain-containing protein 17 67 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113032&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278411 104007383 CHEMBL28141 ZINC13441611 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204828 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)17-4-2-1-3-13(17)12-31-15-6-8-16(9-7-15)32(29,30)25-11-14(26)5-10-18(25)19(27)24-28/h1-4,6-9,14,18,26,28H,5,10-12H2,(H,24,27)/t14-,18-/m1/s1 TVRQFUFQUOUOJG-RDTXWAMCSA-N 50113041 (2R,5R)-5-Hydroxy-1-[4-(2-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL27965 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113041&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9891048 104007392 CHEMBL27965 ZINC13441642 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204829 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(F)c2)cc1 InChI=1S/C19H21FN2O6S/c20-14-3-1-2-13(10-14)12-28-16-4-6-17(7-5-16)29(26,27)22-9-8-15(23)11-18(22)19(24)21-25/h1-7,10,15,18,23,25H,8-9,11-12H2,(H,21,24)/t15-,18+/m0/s1 GPJUMXDCOLWYIL-MAUKXSAKSA-N 50113043 (2R,4S)-1-[4-(3-Fluoro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28299 Disintegrin and metalloproteinase domain-containing protein 17 21 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113043&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278424 104007394 CHEMBL28299 ZINC13441609 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204836 COc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CC[C@H](O)C[C@@H]1C(=O)NO InChI=1S/C20H24N2O7S/c1-28-19-5-3-2-4-14(19)13-29-16-6-8-17(9-7-16)30(26,27)22-11-10-15(23)12-18(22)20(24)21-25/h2-9,15,18,23,25H,10-13H2,1H3,(H,21,24)/t15-,18+/m0/s1 QXWGXKRGYXQPPV-MAUKXSAKSA-N 50113047 (2R,4S)-4-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28360 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113047&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9824331 104007398 CHEMBL28360 ZINC13441627 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204837 COC(=O)[C@@H]1CCN([C@H](C1)C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C15H20N2O7S/c1-23-11-3-5-12(6-4-11)25(21,22)17-8-7-10(15(19)24-2)9-13(17)14(18)16-20/h3-6,10,13,20H,7-9H2,1-2H3,(H,16,18)/t10-,13-/m1/s1 WRHBZMDBWRLMMM-ZWNOBZJWSA-N 50113049 (2R,4R)-2-Hydroxycarbamoyl-1-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid methyl ester::CHEMBL31928 Disintegrin and metalloproteinase domain-containing protein 17 9600 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113049&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278667 104007400 CHEMBL31928 ZINC13441654 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202641 CNCC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C20H22BrN3O5S/c1-14-12-15(21)13-18(20(25)23-26)19(14)24(3)30(27,28)17-8-6-16(7-9-17)29-11-5-4-10-22-2/h6-9,12-13,22,26H,10-11H2,1-3H3,(H,23,25) LNMKFTOPZCDAED-UHFFFAOYSA-N 50111704 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(4-methylamino-but-2-ynyloxy)-benzenesulfonyl]-amino}-benzamide::CHEMBL19269 Disintegrin and metalloproteinase domain-containing protein 17 58 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111704&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10228529 104006229 CHEMBL19269 ZINC13440713 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202642 CCC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C20H21BrN2O5S/c1-4-5-6-11-28-16-7-9-17(10-8-16)29(26,27)23(3)19-14(2)12-15(21)13-18(19)20(24)22-25/h7-10,12-13,25H,4,11H2,1-3H3,(H,22,24) BRHXKZALFBLRIF-UHFFFAOYSA-N 50111712 5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-pent-2-ynyloxy-benzenesulfonyl)-amino]-benzamide::CHEMBL19371 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111712&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9826481 104006237 CHEMBL19371 ZINC13440706 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202653 CN(C)CCCNCC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C24H31BrN4O5S/c1-18-16-19(25)17-22(24(30)27-31)23(18)29(4)35(32,33)21-10-8-20(9-11-21)34-15-6-5-12-26-13-7-14-28(2)3/h8-11,16-17,26,31H,7,12-15H2,1-4H3,(H,27,30) XDKNQAWYSUZUDU-UHFFFAOYSA-N 50111709 5-Bromo-2-({4-[4-(3-dimethylamino-propylamino)-but-2-ynyloxy]-benzenesulfonyl}-methyl-amino)-N-hydroxy-3-methyl-benzamide::CHEMBL276275 Disintegrin and metalloproteinase domain-containing protein 17 29 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111709&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9894201 104006234 CHEMBL276275 ZINC28224873 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202654 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1 InChI=1S/C19H19BrN2O6S/c1-13-11-14(20)12-17(19(24)21-25)18(13)22(2)29(26,27)16-7-5-15(6-8-16)28-10-4-3-9-23/h5-8,11-12,23,25H,9-10H2,1-2H3,(H,21,24) ZEZNNQDUSMNIDE-UHFFFAOYSA-N 50111710 5-Bromo-N-hydroxy-2-{[4-(4-hydroxy-but-2-ynyloxy)-benzenesulfonyl]-methyl-amino}-3-methyl-benzamide::CHEMBL18943 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111710&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9805304 104006235 CHEMBL18943 ZINC03817591 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202657 CC(Oc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO)C#C InChI=1S/C19H19BrN2O5S/c1-5-13(3)27-15-6-8-16(9-7-15)28(25,26)22(4)18-12(2)10-14(20)11-17(18)19(23)21-24/h1,6-11,13,24H,2-4H3,(H,21,23) CSVWGAZPMRHMHB-UHFFFAOYSA-N 50111699 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(1-methyl-prop-2-ynyloxy)-benzenesulfonyl]-amino}-benzamide::CHEMBL19279 Disintegrin and metalloproteinase domain-containing protein 17 122 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111699&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23506747 104006224 CHEMBL19279 ZINC13440704 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202660 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccnc2)cc1 InChI=1S/C21H20BrN3O5S/c1-14-10-16(22)11-19(21(26)24-27)20(14)25(2)31(28,29)18-7-5-17(6-8-18)30-13-15-4-3-9-23-12-15/h3-12,27H,13H2,1-2H3,(H,24,26) IVMSMXBRUPDONM-UHFFFAOYSA-N 50111713 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(pyridin-3-ylmethoxy)-benzenesulfonyl]-amino}-benzamide::CHEMBL276086 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111713&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44272455 104006238 CHEMBL276086 ZINC13440700 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202664 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cccc1C(=O)NO InChI=1S/C19H20N2O5S/c1-4-5-13-26-15-9-11-16(12-10-15)27(24,25)21(3)18-14(2)7-6-8-17(18)19(22)20-23/h6-12,23H,13H2,1-3H3,(H,20,22) IUPDLWWZWJCNBN-UHFFFAOYSA-N 50111705 2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL18742 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111705&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44272249 104006230 CHEMBL18742 ZINC13440715 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202665 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCC#Cc2ccccc2)cc1 InChI=1S/C24H21BrN2O5S/c1-17-15-19(25)16-22(24(28)26-29)23(17)27(2)33(30,31)21-12-10-20(11-13-21)32-14-6-9-18-7-4-3-5-8-18/h3-5,7-8,10-13,15-16,29H,14H2,1-2H3,(H,26,28) PTUSTBHDXAVNPJ-UHFFFAOYSA-N 50111711 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4-(3-phenyl-prop-2-ynyloxy)-benzenesulfonyl]-amino}-benzamide::CHEMBL418737 Disintegrin and metalloproteinase domain-containing protein 17 66 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111711&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9806970 104006236 CHEMBL418737 ZINC28225209 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50202666 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCC#C)cc1 InChI=1S/C18H17BrN2O5S/c1-4-9-26-14-5-7-15(8-6-14)27(24,25)21(3)17-12(2)10-13(19)11-16(17)18(22)20-23/h1,5-8,10-11,23H,9H2,2-3H3,(H,20,22) JMJKKHVSMQBPSU-UHFFFAOYSA-N 50111693 5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-ynyloxy-benzenesulfonyl)-amino]-benzamide::CHEMBL278060 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/s0960-894x(02)00136-1 10.7270/Q2TB1662 11934588 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Killar, LM; Skala, S; Sung, A; Jin, G; Cowling, R; Barone, D; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111693&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868515 104006218 CHEMBL278060 ZINC13440692 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192032 CCOc1ccc(CCC[C@@H]2[C@H](CCCCOc3ccc(C[C@H](NC2=O)C(=O)NC)cc3)C(=O)NO)cc1 InChI=1S/C29H39N3O6/c1-3-37-22-14-10-20(11-15-22)7-6-9-24-25(28(34)32-36)8-4-5-18-38-23-16-12-21(13-17-23)19-26(29(35)30-2)31-27(24)33/h10-17,24-26,36H,3-9,18-19H2,1-2H3,(H,30,35)(H,31,33)(H,32,34)/t24-,25+,26+/m1/s1 HFKQCTSECBMUHK-ZNZIZOMTSA-N 50106016 (7S,8R,11S)-8-[3-(4-ethoxy-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL98770 Disintegrin and metalloproteinase domain-containing protein 17 2.7 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106016&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330095 104001596 CHEMBL98770 ZINC26730832 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192040 Cc1ccc(CCC[C@@H]2[C@H](CCCCOc3ccc(C[C@H](NC2=O)C(=O)c2ccccc2)cc3)C(=O)NO)cc1 InChI=1S/C33H38N2O5/c1-23-13-15-24(16-14-23)8-7-12-28-29(33(38)35-39)11-5-6-21-40-27-19-17-25(18-20-27)22-30(34-32(28)37)31(36)26-9-3-2-4-10-26/h2-4,9-10,13-20,28-30,39H,5-8,11-12,21-22H2,1H3,(H,34,37)(H,35,38)/t28-,29+,30+/m1/s1 GIGQELYOVAVUIF-NGDRWEMDSA-N 50106024 (7S,8R,11S)-11-Benzoyl-9-oxo-8-(3-p-tolyl-propyl)-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7-carboxylic acid hydroxyamide::CHEMBL99547 Disintegrin and metalloproteinase domain-containing protein 17 96 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106024&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9937188 104001604 CHEMBL99547 ZINC26742808 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192046 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3cccc4ccccc34)C(=O)N1)C(=O)NO)cc2 InChI=1S/C31H37N3O5/c1-32-31(37)28-20-21-15-17-24(18-16-21)39-19-5-4-13-27(30(36)34-38)26(29(35)33-28)14-7-11-23-10-6-9-22-8-2-3-12-25(22)23/h2-3,6,8-10,12,15-18,26-28,38H,4-5,7,11,13-14,19-20H2,1H3,(H,32,37)(H,33,35)(H,34,36)/t26-,27+,28+/m1/s1 KAJAADJOOYZIPJ-PKTNWEFCSA-N 50106028 (7S,8R,11S)-8-(3-naphthalen-1-yl-propyl)-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL99103 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106028&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330226 104001608 CHEMBL99103 ZINC26741937 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192047 COc1cc(Oc2ccc(SCC(C)C(=O)NO)cc2)cc(OC)c1OC InChI=1S/C19H23NO6S/c1-12(19(21)20-22)11-27-15-7-5-13(6-8-15)26-14-9-16(23-2)18(25-4)17(10-14)24-3/h5-10,12,22H,11H2,1-4H3,(H,20,21) TZTMRGAOGRZNKP-UHFFFAOYSA-N 50106020 CHEMBL99109::N-Hydroxy-2-methyl-3-[4-(3,4,5-trimethoxy-phenoxy)-phenylsulfanyl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 180 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106020&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329998 104001600 CHEMBL99109 ZINC26739699 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192055 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3cc(C)cc(c3)C(C)C)C(=O)N1)C(=O)NO)cc2 InChI=1S/C31H43N3O5/c1-20(2)24-17-21(3)16-23(18-24)8-7-10-26-27(30(36)34-38)9-5-6-15-39-25-13-11-22(12-14-25)19-28(31(37)32-4)33-29(26)35/h11-14,16-18,20,26-28,38H,5-10,15,19H2,1-4H3,(H,32,37)(H,33,35)(H,34,36)/t26-,27+,28+/m1/s1 YINOLIYDTHQXKP-PKTNWEFCSA-N 50106021 (7S,8R,11S)-8-[3-(3-isopropyl-5-methyl-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL99283 Disintegrin and metalloproteinase domain-containing protein 17 220 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329943 104001601 CHEMBL99283 ZINC26732261 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192068 COc1cc(CCC[C@@H]2[C@H](CCCCOc3ccc(C[C@H](NC2=O)C(=O)c2ccccc2)cc3)C(=O)NO)cc(OC)c1OC InChI=1S/C35H42N2O8/c1-42-30-21-24(22-31(43-2)33(30)44-3)10-9-14-27-28(35(40)37-41)13-7-8-19-45-26-17-15-23(16-18-26)20-29(36-34(27)39)32(38)25-11-5-4-6-12-25/h4-6,11-12,15-18,21-22,27-29,41H,7-10,13-14,19-20H2,1-3H3,(H,36,39)(H,37,40)/t27-,28+,29+/m1/s1 HKZHDTJNCBXYPY-ULNSLHSMSA-N 50106031 (7S,8R,11S)-11-benzoyl-9-oxo-8-[3-(3,4,5-trimethoxy-phenyl)-propyl]-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7-carboxylic acid hydroxyamide::CHEMBL329232 Disintegrin and metalloproteinase domain-containing protein 17 55 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106031&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330225 104001611 CHEMBL329232 ZINC26739447 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192070 COc1cc(Oc2ccc(cc2)S(=O)(=O)N2CCSC(C)(C)[C@@H]2C(=O)NO)cc(OC)c1OC InChI=1S/C22H28N2O8S2/c1-22(2)20(21(25)23-26)24(10-11-33-22)34(27,28)16-8-6-14(7-9-16)32-15-12-17(29-3)19(31-5)18(13-15)30-4/h6-9,12-13,20,26H,10-11H2,1-5H3,(H,23,25)/t20-/m0/s1 DCDJWNFOPNVBIM-FQEVSTJZSA-N 50106025 (S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::(S)-N-hydroxy-2,2-dimethyl-4-(4-(3,4,5-trimethoxyphenoxy)phenylsulfonyl)thiomorpholine-3-carboxamide::CHEMBL95305 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106025&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330092 104001605 CHEMBL95305 ZINC26730444 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192078 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3cc(cc(c3)C(F)(F)F)C(F)(F)F)C(=O)N1)C(=O)NO)cc2 InChI=1S/C29H33F6N3O5/c1-36-27(41)24-15-17-8-10-21(11-9-17)43-12-3-2-6-23(26(40)38-42)22(25(39)37-24)7-4-5-18-13-19(28(30,31)32)16-20(14-18)29(33,34)35/h8-11,13-14,16,22-24,42H,2-7,12,15H2,1H3,(H,36,41)(H,37,39)(H,38,40)/t22-,23+,24+/m1/s1 IXAIGCQWYVKFMN-SGNDLWITSA-N 50106030 (7S,8R,11S)-8-[3-(3,5-Bis-trifluoromethyl-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL329302 Disintegrin and metalloproteinase domain-containing protein 17 33 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106030 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106030&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330133 104001610 CHEMBL329302 ZINC26735964 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50192087 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3cc(OC)ccc3OC)C(=O)N1)C(=O)NO)cc2 InChI=1S/C29H39N3O7/c1-30-29(35)25-17-19-10-12-21(13-11-19)39-16-5-4-8-24(28(34)32-36)23(27(33)31-25)9-6-7-20-18-22(37-2)14-15-26(20)38-3/h10-15,18,23-25,36H,4-9,16-17H2,1-3H3,(H,30,35)(H,31,33)(H,32,34)/t23-,24+,25+/m1/s1 LBQUSUPCYKIDFL-DSITVLBTSA-N 50106018 (7S,8R,11S)-8-[3-(2,5-dimethoxy-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL99120 Disintegrin and metalloproteinase domain-containing protein 17 6.8 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106018&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330094 104001598 CHEMBL99120 ZINC26730827 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193308 CCC[C@@H]([C@@H](CC1CCCCC1)C(=O)N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C23H38N8O6S/c1-2-7-19(30(35)15-32)17(14-16-8-4-3-5-9-16)20(33)27-18(21(34)28-23-26-12-13-38-23)10-6-11-25-22(24)29-31(36)37/h12-13,15-19,35H,2-11,14H2,1H3,(H,27,33)(H3,24,25,29)(H,26,28,34)/t17-,18+,19+/m1/s1 FWJFNXPZKLJJSG-QYZOEREBSA-N 50106659 (2R,3R)-N-{(1R)-4-Nitroguanyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-2-(cyclohexylmethyl)-3-[formyl(hydroxy)amino]-hexanamide::CHEMBL337042 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106659&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11092884 104002140 CHEMBL337042 ZINC03923974 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193309 CCC[C@@H]([C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](CCCN=C(N)NS(=O)(=O)c1ccccn1)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C29H44N8O6S2/c1-3-7-24(37(41)19-38)22(18-21-12-10-20(2)11-13-21)26(39)34-23(27(40)35-29-33-16-17-44-29)8-6-15-32-28(30)36-45(42,43)25-9-4-5-14-31-25/h4-5,9,14,16-17,19-24,41H,3,6-8,10-13,15,18H2,1-2H3,(H,34,39)(H3,30,32,36)(H,33,35,40)/t20?,21?,22-,23+,24+/m1/s1 QXSADLFWPARWTP-QSBPQZLJSA-N 50106658 3-(Formyl-hydroxy-amino)-2-(4-methyl-cyclohexylmethyl)-hexanoic acid [4-{[amino-(pyridine-2-sulfonylimino)-methyl]-amino}-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL336786 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106658&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11814382 104002139 CHEMBL336786 ZINC27426662 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193310 CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C21H37N7O6S2/c1-5-7-17(28(32)13-29)15(12-14(2)3)18(30)25-16(19(31)26-21-24-10-11-35-21)8-6-9-23-20(22)27-36(4,33)34/h10-11,13-17,32H,5-9,12H2,1-4H3,(H,25,30)(H3,22,23,27)(H,24,26,31)/t15-,16+,17+/m1/s1 ZLIOUDYFRDHHSM-IKGGRYGDSA-N 50106656 3-(Formyl-hydroxy-amino)-2-isobutyl-hexanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL263459::TCMDC-138171 Disintegrin and metalloproteinase domain-containing protein 17 7.9 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106656&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11038896 104002137 CHEMBL263459 ZINC27436845 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193311 CC(C)C[C@H]([C@H](C(C)C)N(O)C=O)C(=O)N[C@@H]([C@H](C)CCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1 InChI=1S/C22H39N7O6S2/c1-13(2)11-16(18(14(3)4)29(33)12-30)19(31)26-17(20(32)27-22-25-9-10-36-22)15(5)7-8-24-21(23)28-37(6,34)35/h9-10,12-18,33H,7-8,11H2,1-6H3,(H,26,31)(H3,23,24,28)(H,25,27,32)/t15-,16-,17+,18+/m1/s1 MQLHBSAEUUVJRX-BDXSIMOUSA-N 50106657 3-(Formyl-hydroxy-amino)-2-isobutyl-4-methyl-pentanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-2-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL135034 Disintegrin and metalloproteinase domain-containing protein 17 35 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106657&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10940712 104002138 CHEMBL135034 ZINC27423291 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193312 CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C20H34N8O6S/c1-4-6-16(27(32)12-29)14(11-13(2)3)17(30)24-15(18(31)25-20-23-9-10-35-20)7-5-8-22-19(21)26-28(33)34/h9-10,12-16,32H,4-8,11H2,1-3H3,(H,24,30)(H3,21,22,26)(H,23,25,31)/t14-,15+,16+/m1/s1 YKVNFNGMIAJYOQ-PMPSAXMXSA-N 50106655 (2R,3R)-N-{(1R)-4-Nitroguanyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-3-[formyl(hydroxy)amino]-2-isobutylhexanamide::CHEMBL336425 Disintegrin and metalloproteinase domain-containing protein 17 4.3 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106655&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9827846 104002136 CHEMBL336425 ZINC13470358 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193313 CC(C)C[C@H]([C@H](Cc1ccccc1)N(O)C=O)C(=O)N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1 InChI=1S/C24H34N8O6S/c1-16(2)13-18(20(31(36)15-33)14-17-7-4-3-5-8-17)21(34)28-19(22(35)29-24-27-11-12-39-24)9-6-10-26-23(25)30-32(37)38/h3-5,7-8,11-12,15-16,18-20,36H,6,9-10,13-14H2,1-2H3,(H,28,34)(H3,25,26,30)(H,27,29,35)/t18-,19+,20+/m1/s1 HDTMIVHMPQVMJD-AABGKKOBSA-N 50106660 (2R,3R)-N-{(1R)-4-Nitroguanyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-2-{(1S)-1--[formyl(hydroxy)amino]-2-phenylethyl}-4-methylpentanamide::CHEMBL337512 Disintegrin and metalloproteinase domain-containing protein 17 49 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106660&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11082293 104002141 CHEMBL337512 ZINC27427017 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193315 CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C22H39N7O6S2/c1-6-7-17(29(33)13-30)16(12-14(2)3)19(31)26-18(20(32)27-22-25-10-11-36-22)15(4)8-9-24-21(23)28-37(5,34)35/h10-11,13-18,33H,6-9,12H2,1-5H3,(H,26,31)(H3,23,24,28)(H,25,27,32)/t15-,16-,17+,18+/m1/s1 FUDBZSGMQCENEH-BDXSIMOUSA-N 50106651 3-(Formyl-hydroxy-amino)-2-isobutyl-hexanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-2-methyl-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL337045 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106651&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10897017 104002132 CHEMBL337045 ZINC27424926 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193321 NC(N[N+]([O-])=O)=NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)[C@H](CCC(F)(F)F)N(O)C=O)C(=O)Nc1nccs1 InChI=1S/C23H35F3N8O6S/c24-23(25,26)9-8-18(33(38)14-35)16(13-15-5-2-1-3-6-15)19(36)30-17(20(37)31-22-29-11-12-41-22)7-4-10-28-21(27)32-34(39)40/h11-12,14-18,38H,1-10,13H2,(H,30,36)(H3,27,28,32)(H,29,31,37)/t16-,17+,18+/m1/s1 JLPMPXKOGZSSRK-SQNIBIBYSA-N 50106652 (2R,3R)-N-{(1R)-4-Nitroguanyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-2-(cyclohexylmethyl)-6,6,6-triflouro-3-[formyl(hydroxy)amino]-hexanamide::CHEMBL134849 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106652&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11039339 104002133 CHEMBL134849 ZINC03923976 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193327 NC(N[N+]([O-])=O)=NCCC[C@H](NC(=O)[C@H](CC1CCCCC1)[C@H](C1CC1)N(O)C=O)C(=O)Nc1nccs1 InChI=1S/C23H36N8O6S/c24-22(29-31(36)37)25-10-4-7-18(21(34)28-23-26-11-12-38-23)27-20(33)17(13-15-5-2-1-3-6-15)19(16-8-9-16)30(35)14-32/h11-12,14-19,35H,1-10,13H2,(H,27,33)(H3,24,25,29)(H,26,28,34)/t17-,18+,19+/m1/s1 HZRAYMWLJLWNAA-QYZOEREBSA-N 50106669 (2R)-5-Nitroguanyl-2-({(2R,3S)-2-(cyclohexylmethyl)-3-cyclopropyl-3-[formyl(hydroxy)amino]propanoyl}-amino)-N-(1,3-thiazol-2-yl)pentamide::CHEMBL135931 Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106669&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11114351 104002150 CHEMBL135931 ZINC03923981 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193329 CCC[C@@H]([C@@H](Cc1ccc(C)s1)C(=O)N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C22H32N8O6S2/c1-3-5-18(29(34)13-31)16(12-15-8-7-14(2)38-15)19(32)26-17(20(33)27-22-25-10-11-37-22)6-4-9-24-21(23)28-30(35)36/h7-8,10-11,13,16-18,34H,3-6,9,12H2,1-2H3,(H,26,32)(H3,23,24,28)(H,25,27,33)/t16-,17+,18+/m1/s1 JEFVBTZAXMPPTH-SQNIBIBYSA-N 50106661 (2R,3R)-N-{(1R)-4-Nitroguanyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-3-[formyl(hydroxy)amino]-2-[(5-methyl-2-thienyl)methyl]hexanamide::CHEMBL135075 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106661 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106661&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10875470 104002142 CHEMBL135075 ZINC27421335 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193337 CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@@H]([C@H](C)CCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C21H36N8O6S/c1-5-6-16(28(33)12-30)15(11-13(2)3)18(31)25-17(19(32)26-21-24-9-10-36-21)14(4)7-8-23-20(22)27-29(34)35/h9-10,12-17,33H,5-8,11H2,1-4H3,(H,25,31)(H3,22,23,27)(H,24,26,32)/t14-,15-,16+,17+/m1/s1 FAEZTVRCESNVJN-NCOADZHNSA-N 50106653 (2R,3R)-N-{(1S,2R)-4-Nitroguanyl-2-methyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-3-[formyl(hydroxy)amino]-2-isobutylhexanamide::CHEMBL334403 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106653 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106653&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11103408 104002134 CHEMBL334403 ZINC13470360 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193341 CC(C)[C@@H]([C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](CCCN=C(N)N[N+]([O-])=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C24H40N8O6S/c1-15(2)20(31(36)14-33)18(13-17-8-6-16(3)7-9-17)21(34)28-19(22(35)29-24-27-11-12-39-24)5-4-10-26-23(25)30-32(37)38/h11-12,14-20,36H,4-10,13H2,1-3H3,(H,28,34)(H3,25,26,30)(H,27,29,35)/t16?,17?,18-,19+,20+/m1/s1 VNCIHKLPBWTDIP-PBDJWPIDSA-N 50106664 (2R,3R)-N-{(1R)-4-Nitroguanyl-1-[(1,3-thiazol-2-ylamino)carbonyl]butyl}-3-[formyl(hydroxy)amino]-4-methyl-2-[(4-cyclohexylmethyl)methyl]-pentanamide::CHEMBL135251 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106664&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10995373 104002145 CHEMBL135251 ZINC03923979 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50193351 CC(C)[C@@H]([C@@H](CC1CCC(C)CC1)C(=O)N[C@@H](CCCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C25H43N7O6S2/c1-16(2)21(32(36)15-33)19(14-18-9-7-17(3)8-10-18)22(34)29-20(23(35)30-25-28-12-13-39-25)6-5-11-27-24(26)31-40(4,37)38/h12-13,15-21,36H,5-11,14H2,1-4H3,(H,29,34)(H3,26,27,31)(H,28,30,35)/t17?,18?,19-,20+,21+/m1/s1 ZAUSLRXPYLUTHB-KJFGXLEFSA-N 50106666 3-(Formyl-hydroxy-amino)-4-methyl-2-(4-methyl-cyclohexylmethyl)-pentanoic acid [4-[(amino-methanesulfonylimino-methyl)-amino]-1-(thiazol-2-ylcarbamoyl)-butyl]-amide::CHEMBL339381 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1021/jm0102654 10.7270/Q24J0DF5 11708926 Rabinowitz, MH; Andrews, RC; Becherer, JD; Bickett, DM; Bubacz, DG; Conway, JG; Cowan, DJ; Gaul, M; Glennon, K; Lambert, MH; Leesnitzer, MA; McDougald, DL; Moss, ML; Musso, DL; Rizzolio, MC GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106666&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11124862 104002147 CHEMBL339381 ZINC27426970 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215072 CCOc1ccc(cc1)C(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO InChI=1S/C26H27N3O7S/c1-3-36-21-10-8-18(9-11-21)26(31)28-17-24(25(30)27-32)29(16-19-6-4-5-7-23(19)28)37(33,34)22-14-12-20(35-2)13-15-22/h4-15,24,32H,3,16-17H2,1-2H3,(H,27,30) FMPSZEWYBZCYDN-UHFFFAOYSA-N 50118969 1-(4-Ethoxy-benzoyl)-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL95708 Disintegrin and metalloproteinase domain-containing protein 17 157 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118969&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44328876 104012217 CHEMBL95708 ZINC13818602 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215079 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)CN1CCN(C)CC1 InChI=1S/C24H31N5O6S/c1-26-11-13-27(14-12-26)17-23(30)28-16-22(24(31)25-32)29(15-18-5-3-4-6-21(18)28)36(33,34)20-9-7-19(35-2)8-10-20/h3-10,22,32H,11-17H2,1-2H3,(H,25,31) QRDJMZMVDBUNNQ-UHFFFAOYSA-N 50118968 4-(4-Methoxy-benzenesulfonyl)-1-[2-(4-methyl-piperazin-1-yl)-acetyl]-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL319808 Disintegrin and metalloproteinase domain-containing protein 17 808 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118968&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9936405 104012216 CHEMBL319808 ZINC22940036 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215080 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1cccs1 InChI=1S/C22H21N3O6S2/c1-31-16-8-10-17(11-9-16)33(29,30)25-13-15-5-2-3-6-18(15)24(14-19(25)21(26)23-28)22(27)20-7-4-12-32-20/h2-12,19,28H,13-14H2,1H3,(H,23,26) VCKCQHDSLLCTDH-UHFFFAOYSA-N 50118975 4-(4-Methoxy-benzenesulfonyl)-1-(thiophene-2-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL95807 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9805473 104012223 CHEMBL95807 ZINC11687898 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215085 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)C1CCCCC1 InChI=1S/C24H29N3O6S/c1-33-19-11-13-20(14-12-19)34(31,32)27-15-18-9-5-6-10-21(18)26(16-22(27)23(28)25-30)24(29)17-7-3-2-4-8-17/h5-6,9-14,17,22,30H,2-4,7-8,15-16H2,1H3,(H,25,28) XJFYJIMKKGZKGX-UHFFFAOYSA-N 50118973 1-Cyclohexanecarbonyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL97908 Disintegrin and metalloproteinase domain-containing protein 17 318 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118973&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9957107 104012221 CHEMBL97908 ZINC13818599 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215087 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(C)=O InChI=1S/C22H23N3O6S/c1-3-4-13-31-18-9-11-19(12-10-18)32(29,30)25-14-17-7-5-6-8-20(17)24(16(2)26)15-21(25)22(27)23-28/h5-12,21,28H,13-15H2,1-2H3,(H,23,27) PRQWPDFKJBVNKQ-UHFFFAOYSA-N 50118972 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isopropenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL97790 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868713 104012220 CHEMBL97790 ZINC13818612 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215090 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1ccccc1 InChI=1S/C27H25N3O6S/c1-2-3-17-36-22-13-15-23(16-14-22)37(34,35)30-18-21-11-7-8-12-24(21)29(19-25(30)26(31)28-33)27(32)20-9-5-4-6-10-20/h4-16,25,33H,17-19H2,1H3,(H,28,31) ASLUWSDEBRNVJV-UHFFFAOYSA-N 50118980 1-Benzoyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL95693 Disintegrin and metalloproteinase domain-containing protein 17 59 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118980&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9936469 104012228 CHEMBL95693 ZINC05494235 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215091 COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(OC)cc1)C(=O)NO InChI=1S/C20H23N3O7S/c1-29-13-19(24)22-12-18(20(25)21-26)23(11-14-5-3-4-6-17(14)22)31(27,28)16-9-7-15(30-2)8-10-16/h3-10,18,26H,11-13H2,1-2H3,(H,21,25) PLYLMXDSDZFWLJ-UHFFFAOYSA-N 50118976 1-(2-Methoxy-acetyl)-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL97898 Disintegrin and metalloproteinase domain-containing protein 17 95 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118976&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868329 104012224 CHEMBL97898 ZINC03923786 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215100 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(C)=O InChI=1S/C19H21N3O6S/c1-13(23)21-12-18(19(24)20-25)22(11-14-5-3-4-6-17(14)21)29(26,27)16-9-7-15(28-2)8-10-16/h3-10,18,25H,11-12H2,1-2H3,(H,20,24) OOCSYABQMHKMLM-UHFFFAOYSA-N 50118974 1-Acetyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL99072 Disintegrin and metalloproteinase domain-containing protein 17 103 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118974&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9802180 104012222 CHEMBL99072 ZINC13818585 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215101 COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(Oc2ccncc2)cc1)C(=O)NO InChI=1S/C24H24N4O7S/c1-34-16-23(29)27-15-22(24(30)26-31)28(14-17-4-2-3-5-21(17)27)36(32,33)20-8-6-18(7-9-20)35-19-10-12-25-13-11-19/h2-13,22,31H,14-16H2,1H3,(H,26,30) UGMUJIKGJCCUOY-UHFFFAOYSA-N 50118981 1-(2-Methoxy-acetyl)-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL316489 Disintegrin and metalloproteinase domain-containing protein 17 157 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118981&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329016 104012229 CHEMBL316489 ZINC13818610 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215105 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)C1CC1 InChI=1S/C24H25N3O6S/c1-2-3-14-33-19-10-12-20(13-11-19)34(31,32)27-15-18-6-4-5-7-21(18)26(24(29)17-8-9-17)16-22(27)23(28)25-30/h4-7,10-13,17,22,30H,8-9,14-16H2,1H3,(H,25,28) BLQAAMGUGMNRQN-UHFFFAOYSA-N 50118979 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-cyclopropanecarbonyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL95460 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118979&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9934997 104012227 CHEMBL95460 ZINC13818618 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50212990 COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](OC(=O)[C@@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C)[C@@H](C)O InChI=1S/C58H95N9O16/c1-30(2)25-38(43(69)29-45(71)64-46(36(12)68)52(74)60-35(11)54(76)66(15)42(27-37-21-18-17-19-22-37)55(77)67-24-20-23-41(67)56(78)81-16)61-51(73)40(28-44(59)70)62-50(72)39(26-31(3)4)63-53(75)48(33(7)8)82-58(80)49(34(9)10)83-57(79)47(32(5)6)65(13)14/h17-19,21-22,30-36,38-43,46-49,68-69H,20,23-29H2,1-16H3,(H2,59,70)(H,60,74)(H,61,73)(H,62,72)(H,63,75)(H,64,71)/t35-,36+,38-,39-,40-,41-,42+,43-,46-,47-,48+,49-/m0/s1 JZYWSTGTBRHGTL-BIXXXADNSA-N 50302107 CHEMBL567893::Grassystatin A Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/jm9009394 10.7270/Q2BG2PXP 19715320 Kwan, JC; Eksioglu, EA; Liu, C; Paul, VJ; Luesch, H University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302107&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44255320 104156468 CHEMBL567893 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215115 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)S(C)(=O)=O InChI=1S/C21H23N3O7S2/c1-3-4-13-31-17-9-11-18(12-10-17)33(29,30)24-14-16-7-5-6-8-19(16)23(32(2,27)28)15-20(24)21(25)22-26/h5-12,20,26H,13-15H2,1-2H3,(H,22,25) DWAPKTBJQHYHER-UHFFFAOYSA-N 50118977 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-methanesulfonyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL95262 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118977&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9827023 104012225 CHEMBL95262 ZINC13818614 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215118 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1ccccc1 InChI=1S/C24H23N3O6S/c1-33-19-11-13-20(14-12-19)34(31,32)27-15-18-9-5-6-10-21(18)26(16-22(27)23(28)25-30)24(29)17-7-3-2-4-8-17/h2-14,22,30H,15-16H2,1H3,(H,25,28) DIIAIQCOHXBJHI-UHFFFAOYSA-N 50118983 1-Benzoyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL96049 Disintegrin and metalloproteinase domain-containing protein 17 95 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118983&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9869819 104012231 CHEMBL96049 ZINC03820450 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215119 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)CCc1ccccc1 InChI=1S/C26H27N3O6S/c1-35-21-12-14-22(15-13-21)36(33,34)29-17-20-9-5-6-10-23(20)28(18-24(29)26(31)27-32)25(30)16-11-19-7-3-2-4-8-19/h2-10,12-15,24,32H,11,16-18H2,1H3,(H,27,31) ZLOBLTFULLQWKZ-UHFFFAOYSA-N 50118967 4-(4-Methoxy-benzenesulfonyl)-1-(3-phenyl-propionyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL100146 Disintegrin and metalloproteinase domain-containing protein 17 207 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118967&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9892518 104012215 CHEMBL100146 ZINC13818591 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215120 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)C1CC1 InChI=1S/C21H23N3O6S/c1-30-16-8-10-17(11-9-16)31(28,29)24-12-15-4-2-3-5-18(15)23(21(26)14-6-7-14)13-19(24)20(25)22-27/h2-5,8-11,14,19,27H,6-7,12-13H2,1H3,(H,22,25) HDOJQDDADGGFGH-UHFFFAOYSA-N 50118978 1-Cyclopropanecarbonyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL412910 Disintegrin and metalloproteinase domain-containing protein 17 69 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118978&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44328937 104012226 CHEMBL412910 ZINC03820451 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215122 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1cc(F)ccc1C InChI=1S/C25H24FN3O6S/c1-16-7-8-18(26)13-21(16)25(31)28-15-23(24(30)27-32)29(14-17-5-3-4-6-22(17)28)36(33,34)20-11-9-19(35-2)10-12-20/h3-13,23,32H,14-15H2,1-2H3,(H,27,30) YPEMWYFQTIBRAB-UHFFFAOYSA-N 50118986 1-(5-Fluoro-2-methyl-benzoyl)-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL97962 Disintegrin and metalloproteinase domain-containing protein 17 271 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118986&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9827807 104012234 CHEMBL97962 ZINC13818595 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215128 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)S(C)(=O)=O InChI=1S/C18H21N3O7S2/c1-28-14-7-9-15(10-8-14)30(26,27)21-11-13-5-3-4-6-16(13)20(29(2,24)25)12-17(21)18(22)19-23/h3-10,17,23H,11-12H2,1-2H3,(H,19,22) ZMVFZGHWXXXQJL-UHFFFAOYSA-N 50118982 1-Methanesulfonyl-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL95486 Disintegrin and metalloproteinase domain-containing protein 17 104 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118982&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9955640 104012230 CHEMBL95486 ZINC13818587 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215136 ONC(=O)C1CN(C(=O)c2cccs2)c2ccccc2CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C27H22ClN3O6S2/c28-19-7-9-20(10-8-19)37-21-11-13-22(14-12-21)39(35,36)31-16-18-4-1-2-5-23(18)30(17-24(31)26(32)29-34)27(33)25-6-3-15-38-25/h1-15,24,34H,16-17H2,(H,29,32) YQCWPKHRHVYSBQ-UHFFFAOYSA-N 50118971 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-(thiophene-2-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL97788 Disintegrin and metalloproteinase domain-containing protein 17 254 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44328971 104012219 CHEMBL97788 ZINC26726769 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215139 ONC(=O)C1CN(C(=O)c2ccccc2)c2ccccc2CN1S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C29H24ClN3O6S/c30-22-10-12-23(13-11-22)39-24-14-16-25(17-15-24)40(37,38)33-18-21-8-4-5-9-26(21)32(19-27(33)28(34)31-36)29(35)20-6-2-1-3-7-20/h1-17,27,36H,18-19H2,(H,31,34) PAAGUAHWPSXIJP-UHFFFAOYSA-N 50118970 1-Benzoyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL330588 Disintegrin and metalloproteinase domain-containing protein 17 528 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118970&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329040 104012218 CHEMBL330588 ZINC26722484 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215140 COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1)C(=O)NO InChI=1S/C25H24ClN3O7S/c1-35-16-24(30)28-15-23(25(31)27-32)29(14-17-4-2-3-5-22(17)28)37(33,34)21-12-10-20(11-13-21)36-19-8-6-18(26)7-9-19/h2-13,23,32H,14-16H2,1H3,(H,27,31) UTFGYUICVDXOSK-UHFFFAOYSA-N 50118984 4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-(2-methoxy-acetyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL316822 Disintegrin and metalloproteinase domain-containing protein 17 157 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118984&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329253 104012232 CHEMBL316822 ZINC26727206 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50215142 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C30H27N3O6S/c1-39-25-15-17-26(18-16-25)40(37,38)33-19-24-9-5-6-10-27(24)32(20-28(33)29(34)31-36)30(35)23-13-11-22(12-14-23)21-7-3-2-4-8-21/h2-18,28,36H,19-20H2,1H3,(H,31,34) LXRKTOCLXUHNEM-UHFFFAOYSA-N 50118985 1-(Biphenyl-4-carbonyl)-4-(4-methoxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL430664 Disintegrin and metalloproteinase domain-containing protein 17 199 ChEMBL 10.1016/s0960-894x(02)00633-9 10.7270/Q2JS9PSH 12270165 Nelson, FC; Delos Santos, E; Levin, JI; Chen, JM; Skotnicki, JS; DiJoseph, JF; Sharr, MA; Sung, A; Killar, LM; Cowling, R; Jin, G; Roth, CE; Albright, JD Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118985&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9959421 104012233 CHEMBL430664 ZINC26721866 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234728 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](N)C(=O)NO)C2=O)cc(C)n1 InChI=1S/C20H24N4O4/c1-12-9-14(10-13(2)22-12)11-28-16-5-3-15(4-6-16)24-8-7-17(20(24)26)18(21)19(25)23-27/h3-6,9-10,17-18,27H,7-8,11,21H2,1-2H3,(H,23,25)/t17-,18+/m1/s1 QFBSFEVNNJBNOX-MSOLQXFVSA-N 50129046 (S)-2-Amino-2-{(R)-1-[4-(2,6-dimethyl-pyridin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-N-hydroxy-acetamide::CHEMBL303510 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129046&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44304020 104020708 CHEMBL303510 ZINC13490357 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234738 CC(=O)N[C@@H]([C@H]1CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H26N4O5/c1-15-13-17(20-5-3-4-6-22(20)26-15)14-34-19-9-7-18(8-10-19)29-12-11-21(25(29)32)23(24(31)28-33)27-16(2)30/h3-10,13,21,23,33H,11-12,14H2,1-2H3,(H,27,30)(H,28,31)/t21-,23+/m1/s1 CHRGPXOYOHYPAP-GGAORHGYSA-N 50129055 (S)-2-Acetylamino-N-hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-acetamide::CHEMBL62964 Disintegrin and metalloproteinase domain-containing protein 17 1560 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129055 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129055&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9912183 104020717 CHEMBL62964 ZINC13490347 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234740 C[C@@H]([C@H]1CCN(C1=O)c1ccc(OCc2ccccc2)cc1)N(O)C=O InChI=1S/C20H22N2O4/c1-15(22(25)14-23)19-11-12-21(20(19)24)17-7-9-18(10-8-17)26-13-16-5-3-2-4-6-16/h2-10,14-15,19,25H,11-13H2,1H3/t15-,19+/m0/s1 VJDIWGRVXNTKIX-HNAYVOBHSA-N 50129053 (S)-N-{1-[(R)-1-(4-Benzyloxy-phenyl)-2-oxo-pyrrolidin-3-yl]-ethyl}-N-hydroxy-formamide::CHEMBL62455 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129053&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9950475 104020715 CHEMBL62455 ZINC13490359 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234752 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](N)C(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C23H24N4O4/c1-14-12-15(18-4-2-3-5-20(18)25-14)13-31-17-8-6-16(7-9-17)27-11-10-19(23(27)29)21(24)22(28)26-30/h2-9,12,19,21,30H,10-11,13,24H2,1H3,(H,26,28)/t19-,21+/m1/s1 DCPYFXNPRQTWHH-CTNGQTDRSA-N 50129041 (S)-2-Amino-N-hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-acetamide::CHEMBL64586 Disintegrin and metalloproteinase domain-containing protein 17 1700 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129041&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9953909 104020703 CHEMBL64586 ZINC13490344 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234756 C[C@H]([C@H]1CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C24H25N3O4/c1-15-13-17(21-5-3-4-6-22(21)25-15)14-31-19-9-7-18(8-10-19)27-12-11-20(24(27)29)16(2)23(28)26-30/h3-10,13,16,20,30H,11-12,14H2,1-2H3,(H,26,28)/t16-,20-/m1/s1 DHZSRYYUAYXLLX-OXQOHEQNSA-N 50129047 (R)-N-Hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-propionamide::CHEMBL62740 Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129047&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9823391 104020709 CHEMBL62740 ZINC13490341 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234769 C[C@@H]([C@H]1CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)N(O)C=O InChI=1S/C24H25N3O4/c1-16-13-18(22-5-3-4-6-23(22)25-16)14-31-20-9-7-19(8-10-20)26-12-11-21(24(26)29)17(2)27(30)15-28/h3-10,13,15,17,21,30H,11-12,14H2,1-2H3/t17-,21+/m0/s1 QTGLVPVEYPPUEP-LAUBAEHRSA-N 50129056 (S)-N-Hydroxy-N-(1-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-ethyl)-formamide::CHEMBL64281 Disintegrin and metalloproteinase domain-containing protein 17 8700.0 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129056 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129056&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9866770 104020718 CHEMBL64281 ZINC13490356 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234772 CN(C)[C@@H]([C@H]1CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H28N4O4/c1-16-14-17(20-6-4-5-7-22(20)26-16)15-33-19-10-8-18(9-11-19)29-13-12-21(25(29)31)23(28(2)3)24(30)27-32/h4-11,14,21,23,32H,12-13,15H2,1-3H3,(H,27,30)/t21-,23+/m1/s1 LKSPKYMQSGHZEA-GGAORHGYSA-N 50129049 (S)-2-Dimethylamino-N-hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-acetamide::CHEMBL303370 Disintegrin and metalloproteinase domain-containing protein 17 1500 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129049 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129049&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9846501 104020711 CHEMBL303370 ZINC13490345 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234781 CCC[C@H](C(=O)NO)[C@@]1(N)CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H30N4O4/c1-3-6-22(24(31)29-33)26(27)13-14-30(25(26)32)19-9-11-20(12-10-19)34-16-18-15-17(2)28-23-8-5-4-7-21(18)23/h4-5,7-12,15,22,33H,3,6,13-14,16,27H2,1-2H3,(H,29,31)/t22-,26+/m1/s1 JTEKRZIXTMGGJR-GJZUVCINSA-N 50129054 (S)-2-{(S)-3-Amino-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-pentanoic acid hydroxyamide::CHEMBL417411 Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129054 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129054&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9847191 104020716 CHEMBL417411 ZINC13490353 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234785 C[C@H](C(=O)NO)[C@]1(CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)N(C)C InChI=1S/C26H30N4O4/c1-17-15-19(22-7-5-6-8-23(22)27-17)16-34-21-11-9-20(10-12-21)30-14-13-26(25(30)32,29(3)4)18(2)24(31)28-33/h5-12,15,18,33H,13-14,16H2,1-4H3,(H,28,31)/t18-,26+/m1/s1 VQXXXMXDXGETFY-DWXRJYCRSA-N 50129045 (S)-2-{(S)-3-Dimethylamino-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-N-hydroxy-propionamide::CHEMBL59968 Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129045&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9934053 104020707 CHEMBL59968 ZINC13490354 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234787 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](NC(=O)C(C)(C)C)C(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C28H32N4O5/c1-17-15-18(21-7-5-6-8-23(21)29-17)16-37-20-11-9-19(10-12-20)32-14-13-22(26(32)34)24(25(33)31-36)30-27(35)28(2,3)4/h5-12,15,22,24,36H,13-14,16H2,1-4H3,(H,30,35)(H,31,33)/t22-,24+/m1/s1 VOKDMWUXBXSQQZ-VWNXMTODSA-N 50129050 CHEMBL432333::N-(((S)-Hydroxycarbamoyl)-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-methyl)-2,2-dimethyl-propionamide Disintegrin and metalloproteinase domain-containing protein 17 4950 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129050 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129050&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9827469 104020712 CHEMBL432333 ZINC13490349 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234797 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](N3CCCC3)C(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C27H30N4O4/c1-18-16-19(22-6-2-3-7-24(22)28-18)17-35-21-10-8-20(9-11-21)31-15-12-23(27(31)33)25(26(32)29-34)30-13-4-5-14-30/h2-3,6-11,16,23,25,34H,4-5,12-15,17H2,1H3,(H,29,32)/t23-,25+/m1/s1 FDOUDYUDNHWREP-NOZRDPDXSA-N 50129058 (S)-N-Hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-2-pyrrolidin-1-yl-acetamide::CHEMBL292546 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129058 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129058&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44304230 104020720 CHEMBL292546 ZINC26161512 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234798 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](O)C(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C23H23N3O5/c1-14-12-15(18-4-2-3-5-20(18)24-14)13-31-17-8-6-16(7-9-17)26-11-10-19(23(26)29)21(27)22(28)25-30/h2-9,12,19,21,27,30H,10-11,13H2,1H3,(H,25,28)/t19-,21+/m1/s1 FTQUTXYBANDKFP-CTNGQTDRSA-N 50129052 (S)-2,N-Dihydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-acetamide::CHEMBL64739 Disintegrin and metalloproteinase domain-containing protein 17 2400 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129052 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129052&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9888429 104020714 CHEMBL64739 ZINC13490343 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234802 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](NC(=O)OC(C)(C)C)C(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C28H32N4O6/c1-17-15-18(21-7-5-6-8-23(21)29-17)16-37-20-11-9-19(10-12-20)32-14-13-22(26(32)34)24(25(33)31-36)30-27(35)38-28(2,3)4/h5-12,15,22,24,36H,13-14,16H2,1-4H3,(H,30,35)(H,31,33)/t22-,24+/m1/s1 LJHSZEIWFDSULF-VWNXMTODSA-N 50129057 (((S)-Hydroxycarbamoyl)-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-methyl)-carbamic acid tert-butyl ester::CHEMBL303983 Disintegrin and metalloproteinase domain-containing protein 17 420 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129057 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129057&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9828039 104020719 CHEMBL303983 ZINC03816571 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239106 COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO InChI=1S/C13H18N2O8S/c1-23-7-2-4-8(5-3-7)24(21,22)15-6-9(16)11(17)12(18)10(15)13(19)14-20/h2-5,9-12,16-18,20H,6H2,1H3,(H,14,19)/t9-,10+,11+,12+/m0/s1 SSQXFNKOLMHXPO-IRCOFANPSA-N 50131383 (2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL90321 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131383 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131383&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10172417 104022555 CHEMBL90321 ZINC13537253 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239107 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(OC2CCCCC2)cc1 InChI=1S/C18H26N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h6-9,11,14-17,21-23,25H,1-5,10H2,(H,19,24)/t14-,15+,16+,17+/m0/s1 KFASYAQTQCGPKV-YLFCFFPRSA-N 50131382 (2R,3R,4R,5S)-1-(4-Cyclohexyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL327578 Disintegrin and metalloproteinase domain-containing protein 17 67 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131382&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325072 104022554 CHEMBL327578 ZINC13537272 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239109 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C18H20N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15+,16+,17+/m0/s1 WLWNRAWQDZRXMB-YLFCFFPRSA-N 50131385 (2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::(2R,3R,4R,5S)-N,3,4,5-tetrahydroxy-1-(4-phenoxyphenylsulfonyl)piperidine-2-carboxamide::CHEMBL61193 Disintegrin and metalloproteinase domain-containing protein 17 2.3 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131385&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910222 104022557 CHEMBL61193 6514 ZINC13537266 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239117 CCOCCOc1ccc(cc1)S(=O)(=O)N1C[C@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO InChI=1S/C16H24N2O9S/c1-2-26-7-8-27-10-3-5-11(6-4-10)28(24,25)18-9-12(19)14(20)15(21)13(18)16(22)17-23/h3-6,12-15,19-21,23H,2,7-9H2,1H3,(H,17,22)/t12-,13+,14+,15+/m0/s1 AHSZJHCTCQGTRY-GBJTYRQASA-N 50131388 (2R,3R,4R,5S)-1-[4-(2-Ethoxy-ethoxy)-benzenesulfonyl]-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL419503 Disintegrin and metalloproteinase domain-containing protein 17 8.7 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131388&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325156 104022560 CHEMBL419503 ZINC13537263 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239118 COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)[C@H](O)[C@@H](O)[C@@H]1C(=O)NO InChI=1S/C13H18N2O8S/c1-23-7-2-4-8(5-3-7)24(21,22)15-6-9(16)11(17)12(18)10(15)13(19)14-20/h2-5,9-12,16-18,20H,6H2,1H3,(H,14,19)/t9-,10+,11-,12-/m0/s1 SSQXFNKOLMHXPO-USZNOCQGSA-N 50131384 (2R,3S,4S,5S)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL93720 Disintegrin and metalloproteinase domain-containing protein 17 510 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131384 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131384&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325159 104022556 CHEMBL93720 ZINC13537256 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239122 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 0.400000 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239126 COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1C(=O)NO InChI=1S/C13H18N2O8S/c1-23-7-2-4-8(5-3-7)24(21,22)15-6-9(16)11(17)12(18)10(15)13(19)14-20/h2-5,9-12,16-18,20H,6H2,1H3,(H,14,19)/t9-,10+,11+,12-/m0/s1 SSQXFNKOLMHXPO-QCNOEVLYSA-N 50131386 (2R,3S,4R,5S)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::(2R,4S)-4-(R)-Hydroxy-5-hydroxy-3-(S)-hydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL92767 Disintegrin and metalloproteinase domain-containing protein 17 71 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131386&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325277 104022558 CHEMBL92767 ZINC13537250 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239131 COc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1C(=O)NO InChI=1S/C13H18N2O8S/c1-23-7-2-4-8(5-3-7)24(21,22)15-6-9(16)11(17)12(18)10(15)13(19)14-20/h2-5,9-12,16-18,20H,6H2,1H3,(H,14,19)/t9-,10-,11+,12+/m1/s1 SSQXFNKOLMHXPO-WYUUTHIRSA-N 50131387 (2R,3S,4S,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL90806 Disintegrin and metalloproteinase domain-containing protein 17 340 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131387&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325157 104022559 CHEMBL90806 ZINC13537260 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239138 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H22N2O8S/c22-15-10-21(16(19(25)20-26)18(24)17(15)23)30(27,28)14-8-6-13(7-9-14)29-11-12-4-2-1-3-5-12/h1-9,15-18,22-24,26H,10-11H2,(H,20,25)/t15-,16+,17+,18+/m0/s1 LQZDEWIIFWHTLX-BSDSXHPESA-N 50131381 (2R,3R,4R,5S)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL93620 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1016/s0960-894x(03)00530-4 10.7270/Q2PC31SG 12873504 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131381 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131381&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325085 104022553 CHEMBL93620 ZINC13537269 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239152 COc1ccc(cc1)S(=O)(=O)N1C[C@@H]2OC(C)(C)O[C@H]2[C@@H](O)[C@@H]1C(=O)NO InChI=1S/C16H22N2O8S/c1-16(2)25-11-8-18(12(15(20)17-21)13(19)14(11)26-16)27(22,23)10-6-4-9(24-3)5-7-10/h4-7,11-14,19,21H,8H2,1-3H3,(H,17,20)/t11-,12+,13-,14+/m0/s1 WOZRCMBDSXXEAJ-RFQIPJPRSA-N 50131390 (1S,2S,6R,7aS)-7-Hydroxy-5-(4-methoxy-benzenesulfonyl)-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-6-carboxylic acid hydroxyamide::CHEMBL330727 Disintegrin and metalloproteinase domain-containing protein 17 40 ChEMBL 10.1016/s0960-894x(03)00531-6 10.7270/Q2JQ10DK 12873505 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131390&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10318916 104022562 CHEMBL330727 ZINC13537278 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239153 COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)[C@H]2OC(C)(C)O[C@H]2[C@@H]1C(=O)NO InChI=1S/C16H22N2O8S/c1-16(2)25-13-11(19)8-18(12(14(13)26-16)15(20)17-21)27(22,23)10-6-4-9(24-3)5-7-10/h4-7,11-14,19,21H,8H2,1-3H3,(H,17,20)/t11-,12+,13+,14-/m0/s1 FABJTKDLHAAFNV-DGAVXFQQSA-N 50131389 (1S,2R,4R,7S)-7-Hydroxy-5-(4-methoxy-benzenesulfonyl)-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-4-carboxylic acid hydroxyamide::CHEMBL93067 Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1016/s0960-894x(03)00531-6 10.7270/Q2JQ10DK 12873505 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131389&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325225 104022561 CHEMBL93067 ZINC13537275 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239156 COc1ccc(cc1)S(=O)(=O)N1C[C@@H]2OC(C)(C)O[C@H]2[C@@H](OC(C)=O)[C@@H]1C(=O)NO InChI=1S/C18H24N2O9S/c1-10(21)27-16-14(17(22)19-23)20(9-13-15(16)29-18(2,3)28-13)30(24,25)12-7-5-11(26-4)6-8-12/h5-8,13-16,23H,9H2,1-4H3,(H,19,22)/t13-,14+,15+,16-/m0/s1 IISMJBOLNRKABL-JJXSEGSLSA-N 50131391 Acetic acid (1S,2R,6R,7aS)-6-hydroxycarbamoyl-5-(4-methoxy-benzenesulfonyl)-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridin-7-yl ester::CHEMBL317307 Disintegrin and metalloproteinase domain-containing protein 17 21 ChEMBL 10.1016/s0960-894x(03)00531-6 10.7270/Q2JQ10DK 12873505 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131391&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325443 104022563 CHEMBL317307 ZINC13537281 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239157 COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1C(=O)NO InChI=1S/C13H18N2O8S/c1-23-7-2-4-8(5-3-7)24(21,22)15-6-9(16)11(17)12(18)10(15)13(19)14-20/h2-5,9-12,16-18,20H,6H2,1H3,(H,14,19)/t9-,10+,11+,12-/m0/s1 SSQXFNKOLMHXPO-QCNOEVLYSA-N 50131386 (2R,3S,4R,5S)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::(2R,4S)-4-(R)-Hydroxy-5-hydroxy-3-(S)-hydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL92767 Disintegrin and metalloproteinase domain-containing protein 17 71 ChEMBL 10.1016/s0960-894x(03)00531-6 10.7270/Q2JQ10DK 12873505 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131386&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44325277 104022558 CHEMBL92767 ZINC13537250 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239160 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 0.400000 ChEMBL 10.1016/s0960-894x(03)00531-6 10.7270/Q2JQ10DK 12873505 Moriyama, H; Tsukida, T; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Hokkaido Collaboration Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234804 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](NC(=O)OC(C)(C)C)C(=O)NO)C2=O)cc(C)n1 InChI=1S/C25H32N4O6/c1-15-12-17(13-16(2)26-15)14-34-19-8-6-18(7-9-19)29-11-10-20(23(29)31)21(22(30)28-33)27-24(32)35-25(3,4)5/h6-9,12-13,20-21,33H,10-11,14H2,1-5H3,(H,27,32)(H,28,30)/t20-,21+/m1/s1 FGGOECPJNJCERE-RTWAWAEBSA-N 50129043 CHEMBL291884::[{(R)-1-[4-(2,6-Dimethyl-pyridin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-((S)-hydroxycarbamoyl)-methyl]-carbamic acid tert-butyl ester Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129043&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44304048 104020705 CHEMBL291884 ZINC13490358 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234809 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](NC(=O)N3CCOCC3)C(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C28H31N5O6/c1-18-16-19(22-4-2-3-5-24(22)29-18)17-39-21-8-6-20(7-9-21)33-11-10-23(27(33)35)25(26(34)31-37)30-28(36)32-12-14-38-15-13-32/h2-9,16,23,25,37H,10-15,17H2,1H3,(H,30,36)(H,31,34)/t23-,25+/m1/s1 YYHIIRGQRSUJIF-NOZRDPDXSA-N 50129051 CHEMBL64262::Morpholine-4-carboxylic acid (((S)-hydroxycarbamoyl)-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-methyl)-amide Disintegrin and metalloproteinase domain-containing protein 17 840.0 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129051 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129051&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9807105 104020713 CHEMBL64262 ZINC26163488 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239418 CC#CCOc1ccc(cc1)S(=O)(=O)NC(C(=O)NO)C(C)(C)SCc1cccnc1 InChI=1S/C21H25N3O5S2/c1-4-5-13-29-17-8-10-18(11-9-17)31(27,28)24-19(20(25)23-26)21(2,3)30-15-16-7-6-12-22-14-16/h6-12,14,19,24,26H,13,15H2,1-3H3,(H,23,25) AYPPVQRNMZPQMU-UHFFFAOYSA-N 50131520 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylthio)butanamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylsulfanyl)-butyramide::CHEMBL316928 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131520 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131520&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327409 104022658 CHEMBL316928 ZINC13537412 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239421 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](C)C(=O)NO InChI=1S/C13H16N2O5S/c1-3-4-9-20-11-5-7-12(8-6-11)21(18,19)15-10(2)13(16)14-17/h5-8,10,15,17H,9H2,1-2H3,(H,14,16)/t10-/m1/s1 FNRFZJFDQHKMHF-SNVBAGLBSA-N 50131523 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxypropanamide::(R)-2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-propionamide::CHEMBL94948 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131523 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131523&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327181 104022661 CHEMBL94948 ZINC13537381 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239423 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)C(CSCc1cccnc1)C(=O)NO InChI=1S/C20H23N3O5S2/c1-3-4-12-28-17-7-9-18(10-8-17)30(26,27)23(2)19(20(24)22-25)15-29-14-16-6-5-11-21-13-16/h5-11,13,19,25H,12,14-15H2,1-2H3,(H,22,24) TXTZEVLHPGQYAR-UHFFFAOYSA-N 50131519 2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-3-(pyridin-3-ylmethylthio)propanamide::2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-(pyridin-3-ylmethylsulfanyl)-propionamide::CHEMBL316298 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131519 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131519&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9803771 104022657 CHEMBL316298 ZINC13537406 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239425 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)[C@H](C(C)C)C(=O)NO InChI=1S/C16H22N2O5S/c1-5-6-11-23-13-7-9-14(10-8-13)24(21,22)18(4)15(12(2)3)16(19)17-20/h7-10,12,15,20H,11H2,1-4H3,(H,17,19)/t15-/m1/s1 AOGWJSJATLXUOJ-OAHLLOKOSA-N 50131524 (R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-3-methylbutanamide::(R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-butyramide::CHEMBL94357 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131524&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11279665 104022662 CHEMBL94357 ZINC13537390 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239429 CNCCOc1ccc(cc1)[C@@H](NS(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C21H25N3O6S/c1-3-4-14-29-18-9-11-19(12-10-18)31(27,28)24-20(21(25)23-26)16-5-7-17(8-6-16)30-15-13-22-2/h5-12,20,22,24,26H,13-15H2,1-2H3,(H,23,25)/t20-/m1/s1 BTZMVJPRQAIPRP-HXUWFJFHSA-N 50131525 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-2-(4-(2-(methylamino)ethoxy)phenyl)acetamide::(R)-2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-2-[4-(2-methylamino-ethoxy)-phenyl]-acetamide::CHEMBL96636 Disintegrin and metalloproteinase domain-containing protein 17 18 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131525&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327432 104022663 CHEMBL96636 ZINC13537421 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239439 CC#CCSc1ccc(cc1)S(=O)(=O)N(C)CC(=O)NO InChI=1S/C13H16N2O4S2/c1-3-4-9-20-11-5-7-12(8-6-11)21(18,19)15(2)10-13(16)14-17/h5-8,17H,9-10H2,1-2H3,(H,14,16) RLUGMDBAWBLDJQ-UHFFFAOYSA-N 50131522 2-[(4-But-2-ynylsulfanyl-benzenesulfonyl)-methyl-amino]-N-hydroxy-acetamide::CHEMBL94518 Disintegrin and metalloproteinase domain-containing protein 17 38 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131522 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131522&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9840395 104022660 CHEMBL94518 ZINC13537430 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239440 CC#CCOc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)Cc1cccnc1 InChI=1S/C18H19N3O5S/c1-2-3-11-26-16-6-8-17(9-7-16)27(24,25)21(14-18(22)20-23)13-15-5-4-10-19-12-15/h4-10,12,23H,11,13-14H2,1H3,(H,20,22) ZOPDCQZNGWSOLM-UHFFFAOYSA-N 50131530 2-(4-(but-2-ynyloxy)-N-(pyridin-3-ylmethyl)phenylsulfonamido)-N-hydroxyacetamide::2-[(4-But-2-ynyloxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-N-hydroxy-acetamide::CHEMBL92927 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131530 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131530&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22645081 104022668 CHEMBL92927 ZINC13537378 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239444 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)[C@H](C)C(=O)NO InChI=1S/C14H18N2O5S/c1-4-5-10-21-12-6-8-13(9-7-12)22(19,20)16(3)11(2)14(17)15-18/h6-9,11,18H,10H2,1-3H3,(H,15,17)/t11-/m1/s1 RMUMGJZUGCOZOV-LLVKDONJSA-N 50131527 (R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxypropanamide::(R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-propionamide::CHEMBL94643 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131527&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327443 104022665 CHEMBL94643 ZINC13537384 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239447 CC#CCOc1ccc(cc1)S(=O)(=O)NCCC(=O)NO InChI=1S/C13H16N2O5S/c1-2-3-10-20-11-4-6-12(7-5-11)21(18,19)14-9-8-13(16)15-17/h4-7,14,17H,8-10H2,1H3,(H,15,16) LXSYXSGOVAASBA-UHFFFAOYSA-N 50131529 3-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-propionamide::CHEMBL97762 Disintegrin and metalloproteinase domain-containing protein 17 145 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131529 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131529&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9926779 104022667 CHEMBL97762 ZINC13537436 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239448 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)C(C(=O)NO)C(C)(C)SCc1cccnc1 InChI=1S/C22H27N3O5S2/c1-5-6-14-30-18-9-11-19(12-10-18)32(28,29)25(4)20(21(26)24-27)22(2,3)31-16-17-8-7-13-23-15-17/h7-13,15,20,27H,14,16H2,1-4H3,(H,24,26) JBVXKMHBLNDBBV-UHFFFAOYSA-N 50131531 2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylthio)butanamide::2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-3-methyl-3-(pyridin-3-ylmethylsulfanyl)-butyramide::CHEMBL96637 Disintegrin and metalloproteinase domain-containing protein 17 54 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131531&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10227522 104022669 CHEMBL96637 ZINC13537418 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239449 CC#CCOc1ccc(cc1)S(=O)(=O)NC(CSCc1cccnc1)C(=O)NO InChI=1S/C19H21N3O5S2/c1-2-3-11-27-16-6-8-17(9-7-16)29(25,26)22-18(19(23)21-24)14-28-13-15-5-4-10-20-12-15/h4-10,12,18,22,24H,11,13-14H2,1H3,(H,21,23) XDSILIXRMZXTNX-UHFFFAOYSA-N 50131518 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3-(pyridin-3-ylmethylthio)propanamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-3-(pyridin-3-ylmethylsulfanyl)-propionamide::CHEMBL96396 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131518 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131518&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327755 104022656 CHEMBL96396 ZINC13537400 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239455 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](C(C)O)C(=O)NO InChI=1S/C14H18N2O6S/c1-3-4-9-22-11-5-7-12(8-6-11)23(20,21)16-13(10(2)17)14(18)15-19/h5-8,10,13,16-17,19H,9H2,1-2H3,(H,15,18)/t10?,13-/m1/s1 VMOSDDURWLNMNG-JLOHTSLTSA-N 50131517 (1R,4R)-2-(4-But-2-ynyloxy-benzenesulfonylamino)-3,N-dihydroxy-butyramide::(2R,3R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3-dihydroxybutanamide::(R)-2-(4-But-2-ynyloxy-benzenesulfonylamino)-3,N-dihydroxy-butyramide::CHEMBL96417 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131517 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131517&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9798114 104022655 CHEMBL96417 ZINC05494211 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239458 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)CC(=O)NO InChI=1S/C13H16N2O5S/c1-3-4-9-20-11-5-7-12(8-6-11)21(18,19)15(2)10-13(16)14-17/h5-8,17H,9-10H2,1-2H3,(H,14,16) DQDPBMDGDOPPLK-UHFFFAOYSA-N 26550 2-{[4-(but-2-yn-1-yloxy)benzene](methyl)sulfonamido}-N-hydroxyacetamide::BMCL1844 Compound 1::CHEMBL321556::butynyloxy containing compound, 1 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26550&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9948666 56464987 CHEMBL321556 ZINC13537375 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239461 CN(CC(=O)NO)S(=O)(=O)c1ccc(NCC#C)cc1 InChI=1S/C12H15N3O4S/c1-3-8-13-10-4-6-11(7-5-10)20(18,19)15(2)9-12(16)14-17/h1,4-7,13,17H,8-9H2,2H3,(H,14,16) DFRHCKHXGKQVLI-UHFFFAOYSA-N 50131535 CHEMBL94386::N-Hydroxy-2-[methyl-(4-prop-2-ynylamino-benzenesulfonyl)-amino]-acetamide Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131535&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9861014 104022673 CHEMBL94386 ZINC13537427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239462 CC#CCOc1ccc(cc1)S(=O)(=O)NC(C)(C)C(=O)NO InChI=1S/C14H18N2O5S/c1-4-5-10-21-11-6-8-12(9-7-11)22(19,20)16-14(2,3)13(17)15-18/h6-9,16,18H,10H2,1-3H3,(H,15,17) LRYRCUJGWNCKPO-UHFFFAOYSA-N 50131534 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-2-methylpropanamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-2-methyl-propionamide::CHEMBL94363 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131534&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9945200 104022672 CHEMBL94363 ZINC13537394 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239465 CC#CCOc1ccc(cc1)S(=O)(=O)NCC(=O)NO InChI=1S/C12H14N2O5S/c1-2-3-8-19-10-4-6-11(7-5-10)20(17,18)13-9-12(15)14-16/h4-7,13,16H,8-9H2,1H3,(H,14,15) XRLMAIWPTHLVKY-UHFFFAOYSA-N 50131516 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyacetamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-acetamide::CHEMBL94715 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131516&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9966028 104022654 CHEMBL94715 ZINC13537372 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239466 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@@H](C(=O)NO)C(C)(C)C InChI=1S/C16H22N2O5S/c1-5-6-11-23-12-7-9-13(10-8-12)24(21,22)18-14(15(19)17-20)16(2,3)4/h7-10,14,18,20H,11H2,1-4H3,(H,17,19)/t14-/m0/s1 GHKVZKUXCOXDAW-AWEZNQCLSA-N 50131532 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3,3-dimethylbutanamide::(R)-2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-3,3-dimethyl-butyramide::CHEMBL317624 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131532 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131532&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327386 104022670 CHEMBL317624 ZINC13537392 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239468 CNCCOc1ccc(cc1)[C@@H](N(C)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C22H27N3O6S/c1-4-5-15-30-19-10-12-20(13-11-19)32(28,29)25(3)21(22(26)24-27)17-6-8-18(9-7-17)31-16-14-23-2/h6-13,21,23,27H,14-16H2,1-3H3,(H,24,26)/t21-/m1/s1 QCHHXEMLMRDLDA-OAQYLSRUSA-N 50131526 (R)-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-2-(4-(2-(methylamino)ethoxy)phenyl)acetamide::(R)-2-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-2-[4-(2-methylamino-ethoxy)-phenyl]-acetamide::CHEMBL98061 Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131526&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327681 104022664 CHEMBL98061 ZINC13537424 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239477 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)CCC(=O)NO InChI=1S/C14H18N2O5S/c1-3-4-11-21-12-5-7-13(8-6-12)22(19,20)16(2)10-9-14(17)15-18/h5-8,18H,9-11H2,1-2H3,(H,15,17) RWOPWLLDIYQNCW-UHFFFAOYSA-N 50131533 3-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-N-hydroxy-propionamide::CHEMBL96419 Disintegrin and metalloproteinase domain-containing protein 17 73 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131533&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9927353 104022671 CHEMBL96419 ZINC03820778 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239484 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](C(C)C)C(=O)NO InChI=1S/C15H20N2O5S/c1-4-5-10-22-12-6-8-13(9-7-12)23(20,21)17-14(11(2)3)15(18)16-19/h6-9,11,14,17,19H,10H2,1-3H3,(H,16,18)/t14-/m1/s1 LAGAITXTFHYXGS-CQSZACIVSA-N 50131521 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxy-3-methylbutanamide::(R)-2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-3-methyl-butyramide::CHEMBL328751 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/s0960-894x(03)00514-6 10.7270/Q21N80H7 12873518 Levin, JI; Chen, JM; Cheung, K; Cole, D; Crago, C; Santos, ED; Du, X; Khafizova, G; MacEwan, G; Niu, C; Salaski, EJ; Zask, A; Cummons, T; Sung, A; Xu, J; Zhang, Y; Xu, W; Ayral-Kaloustian, S; Jin, G; Cowling, R; Barone, D; Mohler, KM; Black, RA; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131521 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131521&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44327407 104022659 CHEMBL328751 ZINC13537387 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234088 COc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 InChI=1S/C17H15N3O3/c1-23-12-6-4-5-11(9-12)10-18-17(22)15-19-14-8-3-2-7-13(14)16(21)20-15/h2-9H,10H2,1H3,(H,18,22)(H,19,20,21) AARSEFXVCWMMKV-UHFFFAOYSA-N 50025159 CHEMBL3337869 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/j.bmc.2014.07.025 10.7270/Q27S7QBJ 25192810 Nara, H; Sato, K; Naito, T; Mototani, H; Oki, H; Yamamoto, Y; Kuno, H; Santou, T; Kanzaki, N; Terauchi, J; Uchikawa, O; Kori, M Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025159&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search WGG 3WV2 118987537 313065064 CHEMBL3337869 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234089 COc1cccc(CNC(=O)c2nc3scc(COCc4ccc(cc4)C(O)=O)c3c(=O)[nH]2)c1 InChI=1S/C24H21N3O6S/c1-32-18-4-2-3-15(9-18)10-25-22(29)20-26-21(28)19-17(13-34-23(19)27-20)12-33-11-14-5-7-16(8-6-14)24(30)31/h2-9,13H,10-12H2,1H3,(H,25,29)(H,30,31)(H,26,27,28) CDQRIIUMNLMHRH-UHFFFAOYSA-N 50025160 CHEMBL3337894 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/j.bmc.2014.07.025 10.7270/Q27S7QBJ 25192810 Nara, H; Sato, K; Naito, T; Mototani, H; Oki, H; Yamamoto, Y; Kuno, H; Santou, T; Kanzaki, N; Terauchi, J; Uchikawa, O; Kori, M Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025160&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72348232 313065065 CHEMBL3337894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234090 ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22) ROSNVSQTEGHUKU-UHFFFAOYSA-N 11863 4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N-hydroxyoxane-4-carboxamide::CHEMBL440498::RS 130830::RS-130,830::alpha-tetrahydropyran beta-sulfone 1B Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmc.2014.07.025 10.7270/Q27S7QBJ 25192810 Nara, H; Sato, K; Naito, T; Mototani, H; Oki, H; Yamamoto, Y; Kuno, H; Santou, T; Kanzaki, N; Terauchi, J; Uchikawa, O; Kori, M Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11863&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search RS1 830C 3342298 46512375 CHEMBL440498 DB08490 ZINC01488366 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241909 C[C@H]1[C@@H](N(CCN1Cc1ccccc1)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO InChI=1S/C27H31N3O5S/c1-20-8-6-7-11-23(20)19-35-24-12-14-25(15-13-24)36(33,34)30-17-16-29(18-22-9-4-3-5-10-22)21(2)26(30)27(31)28-32/h3-15,21,26,32H,16-19H2,1-2H3,(H,28,31)/t21-,26+/m0/s1 NKDZJRDULDIJON-HFZDXXHNSA-N 50132619 (2R,3S)-4-Benzyl-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL325150 Disintegrin and metalloproteinase domain-containing protein 17 68 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132619&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339624 104023602 CHEMBL325150 ZINC13553164 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241917 C[C@H]1[C@@H](N(CCN1S(C)(=O)=O)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO InChI=1S/C21H27N3O7S2/c1-15-6-4-5-7-17(15)14-31-18-8-10-19(11-9-18)33(29,30)24-13-12-23(32(3,27)28)16(2)20(24)21(25)22-26/h4-11,16,20,26H,12-14H2,1-3H3,(H,22,25)/t16-,20+/m0/s1 VSZRGCMKCYLOIV-OXJNMPFZSA-N 50132628 (2R,3S)-4-Methanesulfonyl-3-methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL110901 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132628&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339394 104023611 CHEMBL110901 ZINC13553162 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50239802 CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSc1cccs1)C(=O)NO InChI=1S/C23H31N3O4S2/c1-15(2)12-17(18(22(28)26-30)14-32-20-10-7-11-31-20)21(27)25-19(23(29)24-3)13-16-8-5-4-6-9-16/h4-11,15,17-19,30H,12-14H2,1-3H3,(H,24,29)(H,25,27)(H,26,28)/t17-,18+,19+/m1/s1 XFILPEOLDIKJHX-QYZOEREBSA-N 50063918 (2R,3S)-N*4*-Hydroxy-2-isobutyl-N*1*-((S)-1-methylcarbamoyl-2-phenyl-ethyl)-3-(thiophen-2-ylsulfanylmethyl)-succinamide::4-(N-HYDROXYAMINO)-2R-ISOBUTYL-2S-(2-THIENYLTHIOMETHYL)SUCCINYL-L-PHENYLALANINE-N-METHYLAMIDE::4-Methyl-2-[1-methyl-2-(thiophen-2-ylsulfanyl)-ethyl]-pentanoic acid (1-methylcarbamoyl-2-phenyl-ethyl)-amide::BATIMASTAT::BB-94::CHEMBL279786::N*4*-Hydroxy-2-isobutyl-N*1*-(1-methylcarbamoyl-2-phenyl-ethyl)-3-(thiophen-2-ylsulfanylmethyl)-succinamide Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1021/jm0308038 10.7270/Q24F1Q3R 12877590 Fray, MJ; Dickinson, RP; Huggins, JP; Occleston, NL Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063918&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search BAT 1JK3,7W6X,7W6Y,7W6Z,1RM8,4DD8,2J83,2RJQ,1DTH,1MMB 5362422 103959090 CHEMBL279786 DB03880 5145 ZINC03789788 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241922 COc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1cccs1 InChI=1S/C22H21N3O6S2/c1-31-16-8-10-17(11-9-16)33(29,30)25-13-15-5-2-3-6-18(15)24(14-19(25)21(26)23-28)22(27)20-7-4-12-32-20/h2-12,19,28H,13-14H2,1H3,(H,23,26) VCKCQHDSLLCTDH-UHFFFAOYSA-N 50118975 4-(4-Methoxy-benzenesulfonyl)-1-(thiophene-2-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL95807 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9805473 104012223 CHEMBL95807 ZINC11687898 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241924 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2cc(F)ccc2C)cc1)C(=O)NO InChI=1S/C22H26FN3O6S/c1-14-4-5-18(23)12-17(14)13-32-19-6-8-20(9-7-19)33(30,31)26-11-10-25(16(3)27)15(2)21(26)22(28)24-29/h4-9,12,15,21,29H,10-11,13H2,1-3H3,(H,24,28)/t15-,21+/m0/s1 FTFANCIOHXJKDG-YCRPNKLZSA-N 50132623 (2R,3S)-4-Acetyl-1-[4-(5-fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL263054 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132623&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339569 104023606 CHEMBL263054 ZINC13539439 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241929 C[C@@H]1NCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1 InChI=1S/C20H25N3O5S/c1-14-5-3-4-6-16(14)13-28-17-7-9-18(10-8-17)29(26,27)23-12-11-21-15(2)19(23)20(24)22-25/h3-10,15,19,21,25H,11-13H2,1-2H3,(H,22,24)/t15-,19+/m0/s1 IJIWBJJLSPLOBZ-HNAYVOBHSA-N 50132631 (2R,3S)-3-Methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL112232 Disintegrin and metalloproteinase domain-containing protein 17 19 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132631&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339571 104023614 CHEMBL112232 ZINC13539424 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241935 C[C@H]1[C@@H](N(CCN1C)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO InChI=1S/C21H27N3O5S/c1-15-6-4-5-7-17(15)14-29-18-8-10-19(11-9-18)30(27,28)24-13-12-23(3)16(2)20(24)21(25)22-26/h4-11,16,20,26H,12-14H2,1-3H3,(H,22,25)/t16-,20+/m0/s1 NOTPJXXSHYGYMI-OXJNMPFZSA-N 50132630 (2R,3S)-3,4-Dimethyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL322705 Disintegrin and metalloproteinase domain-containing protein 17 31 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132630&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339395 104023613 CHEMBL322705 ZINC13553163 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241938 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H22N2O6S/c22-15-10-11-21(18(12-15)19(23)20-24)28(25,26)17-8-6-16(7-9-17)27-13-14-4-2-1-3-5-14/h1-9,15,18,22,24H,10-13H2,(H,20,23)/t15-,18+/m0/s1 ACEUKQZDNBIUHG-MAUKXSAKSA-N 50113038 (2R,4S)-1-(4-Benzyloxy-benzenesulfonyl)-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL281920 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113038 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113038&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541745 104007389 CHEMBL281920 ZINC13441605 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241941 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1)C(=O)NO InChI=1S/C22H24F3N3O6S/c1-14-20(21(30)26-31)28(12-11-27(14)15(2)29)35(32,33)18-9-7-17(8-10-18)34-13-16-5-3-4-6-19(16)22(23,24)25/h3-10,14,20,31H,11-13H2,1-2H3,(H,26,30)/t14-,20+/m0/s1 YSMSZPWEAVKTEN-VBKZILBWSA-N 50132635 (2R,3S)-4-Acetyl-3-methyl-1-[4-(2-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL322476 Disintegrin and metalloproteinase domain-containing protein 17 2000 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132635&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339544 104023618 CHEMBL322476 ZINC13553158 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241943 COC(=O)N1CCN([C@H]([C@@H]1C)C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1 InChI=1S/C22H27N3O7S/c1-15-6-4-5-7-17(15)14-32-18-8-10-19(11-9-18)33(29,30)25-13-12-24(22(27)31-3)16(2)20(25)21(26)23-28/h4-11,16,20,28H,12-14H2,1-3H3,(H,23,26)/t16-,20+/m0/s1 BVVZNDQVRQLIPW-OXJNMPFZSA-N 50132625 (2S,3R)-3-Hydroxycarbamoyl-2-methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1-carboxylic acid methyl ester::CHEMBL326221 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132625&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339647 104023608 CHEMBL326221 ZINC13553165 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241946 C[C@H]1[C@@H](N(CCN1S(=O)(=O)c1ccc(C)cc1)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO InChI=1S/C27H31N3O7S2/c1-19-8-12-24(13-9-19)38(33,34)29-16-17-30(26(21(29)3)27(31)28-32)39(35,36)25-14-10-23(11-15-25)37-18-22-7-5-4-6-20(22)2/h4-15,21,26,32H,16-18H2,1-3H3,(H,28,31)/t21-,26+/m0/s1 UTQLDSRMYUQUPD-HFZDXXHNSA-N 50132622 (2R,3S)-3-Methyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-4-(toluene-4-sulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL111460 Disintegrin and metalloproteinase domain-containing protein 17 26000 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339742 104023605 CHEMBL111460 ZINC26958258 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241947 C[C@H]1[C@@H](N(CCN1C(=O)Nc1ccccc1)S(=O)(=O)c1ccc(OCc2ccccc2C)cc1)C(=O)NO InChI=1S/C27H30N4O6S/c1-19-8-6-7-9-21(19)18-37-23-12-14-24(15-13-23)38(35,36)31-17-16-30(20(2)25(31)26(32)29-34)27(33)28-22-10-4-3-5-11-22/h3-15,20,25,34H,16-18H2,1-2H3,(H,28,33)(H,29,32)/t20-,25+/m0/s1 OVROAIFGKUSYAZ-NBGIEHNGSA-N 50132637 (2S,3R)-2-Methyl-4-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperazine-1,3-dicarboxylic acid 3-hydroxyamide 1-phenylamide::CHEMBL110994 Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132637&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339648 104023620 CHEMBL110994 ZINC26967544 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241949 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OCC#C)cc1 InChI=1S/C18H17BrN2O5S/c1-4-9-26-14-5-7-15(8-6-14)27(24,25)21(3)17-12(2)10-13(19)11-16(17)18(22)20-23/h1,5-8,10-11,23H,9H2,2-3H3,(H,20,22) JMJKKHVSMQBPSU-UHFFFAOYSA-N 50111693 5-Bromo-N-hydroxy-3-methyl-2-[methyl-(4-prop-2-ynyloxy-benzenesulfonyl)-amino]-benzamide::CHEMBL278060 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111693&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868515 104006218 CHEMBL278060 ZINC13440692 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241952 C[C@@H]1NCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H23N3O5S/c1-14-18(19(23)21-24)22(12-11-20-14)28(25,26)17-9-7-16(8-10-17)27-13-15-5-3-2-4-6-15/h2-10,14,18,20,24H,11-13H2,1H3,(H,21,23)/t14-,18+/m0/s1 SHBOXSNAYNDDGN-KBXCAEBGSA-N 50132633 (2R,3S)-1-(4-Benzyloxy-benzenesulfonyl)-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL109833 Disintegrin and metalloproteinase domain-containing protein 17 18000 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132633&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339402 104023616 CHEMBL109833 ZINC13539421 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241953 CC[C@H](C)[C@H](NC(=O)C(CC(C)C)[C@H](C(C)C)N(O)C=O)C(=O)Nc1ccccn1 InChI=1S/C22H36N4O4/c1-7-16(6)19(22(29)24-18-10-8-9-11-23-18)25-21(28)17(12-14(2)3)20(15(4)5)26(30)13-27/h8-11,13-17,19-20,30H,7,12H2,1-6H3,(H,25,28)(H,23,24,29)/t16-,17?,19-,20-/m0/s1 SMZPWUUYPYYHIV-LYKJFQGKSA-N 50132624 (S)-3-(Formyl-hydroxy-amino)-2-isobutyl-4-methyl-pentanoic acid [(1S,2S)-2-methyl-1-(pyridin-2-ylcarbamoyl)-butyl]-amide::CHEMBL111262 Disintegrin and metalloproteinase domain-containing protein 17 40 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132624&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339451 104023607 CHEMBL111262 ZINC26965489 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241961 CCc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CCN([C@@H](C)[C@@H]1C(=O)NO)C(C)=O InChI=1S/C23H29N3O6S/c1-4-18-7-5-6-8-19(18)15-32-20-9-11-21(12-10-20)33(30,31)26-14-13-25(17(3)27)16(2)22(26)23(28)24-29/h5-12,16,22,29H,4,13-15H2,1-3H3,(H,24,28)/t16-,22+/m0/s1 DODLQVHRMPIMNB-KSFYIVLOSA-N 50132626 (2R,3S)-4-Acetyl-1-[4-(2-ethyl-benzyloxy)-benzenesulfonyl]-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL109775 Disintegrin and metalloproteinase domain-containing protein 17 600 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132626&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339575 104023609 CHEMBL109775 ZINC13539430 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241962 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2cc(F)cc(F)c2)cc1)C(=O)NO InChI=1S/C21H23F2N3O6S/c1-13-20(21(28)24-29)26(8-7-25(13)14(2)27)33(30,31)19-5-3-18(4-6-19)32-12-15-9-16(22)11-17(23)10-15/h3-6,9-11,13,20,29H,7-8,12H2,1-2H3,(H,24,28)/t13-,20+/m0/s1 RCOBSDNFRJAUBV-RNODOKPDSA-N 50132636 (2R,3S)-4-Acetyl-1-[4-(3,5-difluoro-benzyloxy)-benzenesulfonyl]-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL111862 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132636&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339570 104023619 CHEMBL111862 ZINC13539433 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241967 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2ccnc3ccccc23)cc1)C(=O)NO InChI=1S/C24H26N4O6S/c1-16-23(24(30)26-31)28(14-13-27(16)17(2)29)35(32,33)20-9-7-19(8-10-20)34-15-18-11-12-25-22-6-4-3-5-21(18)22/h3-12,16,23,31H,13-15H2,1-2H3,(H,26,30)/t16-,23+/m0/s1 IINBMMZSLVIMTL-QMHKHESXSA-N 50132627 (2R,3S)-4-Acetyl-3-methyl-1-[4-(quinolin-4-ylmethoxy)-benzenesulfonyl]-piperazine-2-carboxylic acid hydroxyamide::CHEMBL109326 Disintegrin and metalloproteinase domain-containing protein 17 300 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132627&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339375 104023610 CHEMBL109326 ZINC13553160 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50241975 C[C@H]1[C@@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2cncc3ccccc23)cc1)C(=O)NO InChI=1S/C24H26N4O6S/c1-16-23(24(30)26-31)28(12-11-27(16)17(2)29)35(32,33)21-9-7-20(8-10-21)34-15-19-14-25-13-18-5-3-4-6-22(18)19/h3-10,13-14,16,23,31H,11-12,15H2,1-2H3,(H,26,30)/t16-,23+/m0/s1 GIJWOCNEPGCMND-QMHKHESXSA-N 50132629 (2R,3S)-4-Acetyl-1-[4-(isoquinolin-4-ylmethoxy)-benzenesulfonyl]-3-methyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL111475 Disintegrin and metalloproteinase domain-containing protein 17 400 ChEMBL 10.1016/s0960-894x(03)00666-8 10.7270/Q2Q23ZMM 12951101 Letavic, MA; Barberia, JT; Carty, TJ; Hardink, JR; Liras, J; Lopresti-Morrow, LL; Mitchell, PG; Noe, MC; Reeves, LM; Snow, SL; Stam, EJ; Sweeney, FJ; Vaughn, ML; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132629&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44339462 104023612 CHEMBL111475 ZINC13553159 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231471 C[C@@H](N1CCNc2cc(O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C11H15N3O5S/c1-7(11(16)13-17)14-5-4-12-9-6-8(15)2-3-10(9)20(14,18)19/h2-3,6-7,12,15,17H,4-5H2,1H3,(H,13,16)/t7-/m1/s1 YNTPPOZAYYWSFD-SSDOTTSWSA-N 50127450 CHEMBL51966::N-Hydroxy-2-(7-hydroxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-propionamide Disintegrin and metalloproteinase domain-containing protein 17 391.0 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127450 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127450&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11833533 104019341 CHEMBL51966 ZINC13518127 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231473 CCOc1cc(COc2ccc3c(NCCN([C@H](CCC(=O)OC)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C25H33N3O9S/c1-4-35-19-12-17(13-20(14-19)36-5-2)16-37-18-6-8-23-21(15-18)26-10-11-28(38(23,32)33)22(25(30)27-31)7-9-24(29)34-3/h6,8,12-15,22,26,31H,4-5,7,9-11,16H2,1-3H3,(H,27,30)/t22-/m1/s1 HTAGYDAMQNRLDD-JOCHJYFZSA-N 50127453 4-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-hydroxycarbamoyl-butyric acid methyl ester::CHEMBL53250 Disintegrin and metalloproteinase domain-containing protein 17 6200 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127453 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127453&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11092861 104019344 CHEMBL53250 ZINC29488588 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231479 CCOc1cc(COc2ccc3c(NCCN([C@H](CCCC(=O)OC)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C26H35N3O9S/c1-4-36-20-13-18(14-21(15-20)37-5-2)17-38-19-9-10-24-22(16-19)27-11-12-29(39(24,33)34)23(26(31)28-32)7-6-8-25(30)35-3/h9-10,13-16,23,27,32H,4-8,11-12,17H2,1-3H3,(H,28,31)/t23-/m1/s1 CZUPUFGAPNROGT-HSZRJFAPSA-N 50127452 5-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-5-hydroxycarbamoyl-pentanoic acid methyl ester::CHEMBL299997 Disintegrin and metalloproteinase domain-containing protein 17 24000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127452 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127452&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10325592 104019343 CHEMBL299997 ZINC29486119 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231483 C[C@@H](N1CCNc2cc(Oc3cccc(c3)[N+]([O-])=O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C17H18N4O7S/c1-11(17(22)19-23)20-8-7-18-15-10-14(5-6-16(15)29(20,26)27)28-13-4-2-3-12(9-13)21(24)25/h2-6,9-11,18,23H,7-8H2,1H3,(H,19,22)/t11-/m1/s1 HEHZCMROVKSJTK-LLVKDONJSA-N 50127460 CHEMBL52659::N-Hydroxy-2-[7-(3-nitro-phenoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 470 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127460&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11732585 104019351 CHEMBL52659 ZINC13518198 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231488 C[C@@H](N1CCNc2cc(Oc3ccc(cc3)C(F)(F)F)ccc2S1(=O)=O)C(=O)NO InChI=1S/C18H18F3N3O5S/c1-11(17(25)23-26)24-9-8-22-15-10-14(6-7-16(15)30(24,27)28)29-13-4-2-12(3-5-13)18(19,20)21/h2-7,10-11,22,26H,8-9H2,1H3,(H,23,25)/t11-/m1/s1 MGPQYGIRNDXSAA-LLVKDONJSA-N 50127465 2-[1,1-Dioxo-7-(4-trifluoromethyl-phenoxy)-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL298884 Disintegrin and metalloproteinase domain-containing protein 17 758 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10873958 104019356 CHEMBL298884 ZINC13518186 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231491 COc1cc(COc2ccc3c(NCCN([C@H](CCCCNC(=O)OC(C)(C)C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C28H40N4O9S/c1-28(2,3)41-27(34)30-11-7-6-8-24(26(33)31-35)32-13-12-29-23-17-20(9-10-25(23)42(32,36)37)40-18-19-14-21(38-4)16-22(15-19)39-5/h9-10,14-17,24,29,35H,6-8,11-13,18H2,1-5H3,(H,30,34)(H,31,33)/t24-/m1/s1 QJCXYCVUFZIPQG-XMMPIXPASA-N 50127466 CHEMBL299141::{5-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-5-hydroxycarbamoyl-pentyl}-carbamic acid tert-butyl ester Disintegrin and metalloproteinase domain-containing protein 17 77 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127466 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127466&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11146467 104019357 CHEMBL299141 ZINC29483123 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229488 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2snc(C)c12)C(=O)NO InChI=1S/C21H19N5O5S2/c1-13-18-19(17(20(27)24-28)11-23-21(18)32-25-13)26(12-14-4-3-9-22-10-14)33(29,30)16-7-5-15(31-2)6-8-16/h3-11,28H,12H2,1-2H3,(H,24,27) CBFHYDZLOMACOM-UHFFFAOYSA-N 50126599 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-isothiazolo[5,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL35707 Disintegrin and metalloproteinase domain-containing protein 17 535 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126599&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10277812 104018674 CHEMBL35707 ZINC13489443 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229491 COc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2c(Br)cccc12)C(=O)NO InChI=1S/C18H16BrN3O5S/c1-22(28(25,26)12-8-6-11(27-2)7-9-12)17-13-4-3-5-15(19)16(13)20-10-14(17)18(23)21-24/h3-10,24H,1-2H3,(H,21,23) ULIBGNMOWDICPU-UHFFFAOYSA-N 50126606 8-Bromo-4-[(4-methoxy-benzenesulfonyl)-methyl-amino]-quinoline-3-carboxylic acid hydroxyamide::8-bromo-N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)quinoline-3-carboxamide::CHEMBL37837 Disintegrin and metalloproteinase domain-containing protein 17 296 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126606&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10183408 104018681 CHEMBL37837 ZINC13489434 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231497 COc1cc(COc2ccc3c(NCCN([C@H](CCCCNS(C)(=O)=O)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C24H34N4O9S2/c1-35-19-12-17(13-20(14-19)36-2)16-37-18-7-8-23-21(15-18)25-10-11-28(39(23,33)34)22(24(29)27-30)6-4-5-9-26-38(3,31)32/h7-8,12-15,22,25-26,30H,4-6,9-11,16H2,1-3H3,(H,27,29)/t22-/m1/s1 DNEUAPIVDBXPFN-JOCHJYFZSA-N 50127472 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-6-methanesulfonylamino-hexanoic acid hydroxyamide::CHEMBL416306 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9960075 104019363 CHEMBL416306 ZINC29483126 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231512 C[C@@H](N1CCNc2cc(OCc3ccccc3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C18H21N3O5S/c1-13(18(22)20-23)21-10-9-19-16-11-15(7-8-17(16)27(21,24)25)26-12-14-5-3-2-4-6-14/h2-8,11,13,19,23H,9-10,12H2,1H3,(H,20,22)/t13-/m1/s1 KFIXLPNCOAUSPO-CYBMUJFWSA-N 50127475 2-(7-Benzyloxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide::CHEMBL52423 Disintegrin and metalloproteinase domain-containing protein 17 705 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127475&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10862104 104019366 CHEMBL52423 ZINC13518130 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231513 C[C@@H](N1CCNc2cc(OCc3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C20H25N3O5S/c1-13-8-14(2)10-16(9-13)12-28-17-4-5-19-18(11-17)21-6-7-23(29(19,26)27)15(3)20(24)22-25/h4-5,8-11,15,21,25H,6-7,12H2,1-3H3,(H,22,24)/t15-/m1/s1 WPVBITLNIHHKGY-OAHLLOKOSA-N 50127468 2-[7-(3,5-Dimethyl-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL293358 Disintegrin and metalloproteinase domain-containing protein 17 229 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127468&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11761578 104019359 CHEMBL293358 ZINC13518133 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231522 CCOc1cc(COc2ccc3c(NCCN([C@H](C(C)C)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C24H33N3O7S/c1-5-32-19-11-17(12-20(13-19)33-6-2)15-34-18-7-8-22-21(14-18)25-9-10-27(35(22,30)31)23(16(3)4)24(28)26-29/h7-8,11-14,16,23,25,29H,5-6,9-10,15H2,1-4H3,(H,26,28)/t23-/m1/s1 WJPORLWHPJGLSC-HSZRJFAPSA-N 50127455 2-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-3-methyl-butyramide::CHEMBL54292 Disintegrin and metalloproteinase domain-containing protein 17 51 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127455 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127455&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11027584 104019346 CHEMBL54292 ZINC13518162 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231530 C[C@@H](N1CCNc2ccccc2S1(=O)=O)C(=O)NO InChI=1S/C11H15N3O4S/c1-8(11(15)13-16)14-7-6-12-9-4-2-3-5-10(9)19(14,17)18/h2-5,8,12,16H,6-7H2,1H3,(H,13,15)/t8-/m1/s1 ZPDVGCNXBJNBDB-MRVPVSSYSA-N 50127477 2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide::CHEMBL277972 Disintegrin and metalloproteinase domain-containing protein 17 484 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127477&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11822212 104019368 CHEMBL277972 ZINC13518118 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231536 C[C@@H](N1CCNc2cc(NC(=O)c3cc(C)cc(C)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C20H24N4O5S/c1-12-8-13(2)10-15(9-12)20(26)22-16-4-5-18-17(11-16)21-6-7-24(30(18,28)29)14(3)19(25)23-27/h4-5,8-11,14,21,27H,6-7H2,1-3H3,(H,22,26)(H,23,25)/t14-/m1/s1 AVYWYSFUVCHTCM-CQSZACIVSA-N 50127479 CHEMBL297959::N-[2-(1-Hydroxycarbamoyl-ethyl)-1,1-dioxo-2,3,4,5-tetrahydro-1H-1lambda*6*-benzo[f][1,2,5]thiadiazepin-7-yl]-3,5-dimethyl-benzamide Disintegrin and metalloproteinase domain-containing protein 17 >10010 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127479&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11133809 104019370 CHEMBL297959 ZINC13518177 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231538 CCOc1cc(COc2ccc3c(NCCN([C@H](C)C(=O)NO)S3(=O)=O)c2)cc(OCC)c1 InChI=1S/C22H29N3O7S/c1-4-30-18-10-16(11-19(12-18)31-5-2)14-32-17-6-7-21-20(13-17)23-8-9-25(33(21,28)29)15(3)22(26)24-27/h6-7,10-13,15,23,27H,4-5,8-9,14H2,1-3H3,(H,24,26)/t15-/m1/s1 KZZUIFPIPUBRFP-OAHLLOKOSA-N 50127467 2-[7-(3,5-Diethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL415949 Disintegrin and metalloproteinase domain-containing protein 17 81 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127467&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10863755 104019358 CHEMBL415949 ZINC13518142 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231542 C[C@@H](N1CCNc2cc(Oc3ccc(cc3)-c3ccccc3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C23H23N3O5S/c1-16(23(27)25-28)26-14-13-24-21-15-20(11-12-22(21)32(26,29)30)31-19-9-7-18(8-10-19)17-5-3-2-4-6-17/h2-12,15-16,24,28H,13-14H2,1H3,(H,25,27)/t16-/m1/s1 ZZFYPMWQKLOJIR-MRXNPFEDSA-N 50127462 2-[7-(Biphenyl-4-yloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL51735 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127462&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10917417 104019353 CHEMBL51735 ZINC13518195 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231548 COc1ccc2c(NCCN([C@H](C(C)C)C(=O)NO)S2(=O)=O)c1 InChI=1S/C14H21N3O5S/c1-9(2)13(14(18)16-19)17-7-6-15-11-8-10(22-3)4-5-12(11)23(17,20)21/h4-5,8-9,13,15,19H,6-7H2,1-3H3,(H,16,18)/t13-/m1/s1 OQWWHTLOLOTDPO-CYBMUJFWSA-N 50127458 CHEMBL300394::N-Hydroxy-2-(7-methoxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-3-methyl-butyramide Disintegrin and metalloproteinase domain-containing protein 17 71 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127458&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11824087 104019349 CHEMBL300394 ZINC13518124 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231551 C[C@@H](N1CCNc2cc(Oc3ccccc3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C17H19N3O5S/c1-12(17(21)19-22)20-10-9-18-15-11-14(7-8-16(15)26(20,23)24)25-13-5-3-2-4-6-13/h2-8,11-12,18,22H,9-10H2,1H3,(H,19,21)/t12-/m1/s1 DXGJDBTUJCUBRD-GFCCVEGCSA-N 50127473 2-(1,1-Dioxo-7-phenoxy-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide::CHEMBL53233 Disintegrin and metalloproteinase domain-containing protein 17 734 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127473&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11111616 104019364 CHEMBL53233 ZINC13518192 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231561 C[C@@H](N1CCNc2cc(OCc3cc(C)nc(C)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C19H24N4O5S/c1-12-8-15(9-13(2)21-12)11-28-16-4-5-18-17(10-16)20-6-7-23(29(18,26)27)14(3)19(24)22-25/h4-5,8-10,14,20,25H,6-7,11H2,1-3H3,(H,22,24)/t14-/m1/s1 SZWRRABFHREDHM-CQSZACIVSA-N 50127457 2-[7-(2,6-Dimethyl-pyridin-4-ylmethoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL299796 Disintegrin and metalloproteinase domain-containing protein 17 544 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127457 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127457&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44296974 104019348 CHEMBL299796 ZINC13518147 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231563 COc1cc(CNc2ccc3c(NCCN([C@H](CC(C)C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C23H32N4O6S/c1-15(2)9-21(23(28)26-29)27-8-7-24-20-12-17(5-6-22(20)34(27,30)31)25-14-16-10-18(32-3)13-19(11-16)33-4/h5-6,10-13,15,21,24-25,29H,7-9,14H2,1-4H3,(H,26,28)/t21-/m1/s1 MAPLEBZZVBOXKC-OAQYLSRUSA-N 50127484 2-[7-(3,5-Dimethoxy-benzylamino)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-methyl-pentanoic acid hydroxyamide::CHEMBL54663 Disintegrin and metalloproteinase domain-containing protein 17 56 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127484&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11145437 104019375 CHEMBL54663 ZINC13518174 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229501 ONC(=O)c1cnc2cc(ccc2c1N(Cc1cccnc1)S(=O)(=O)c1ccc(cc1)-c1ccccc1)C(F)(F)F InChI=1S/C29H21F3N4O4S/c30-29(31,32)22-10-13-24-26(15-22)34-17-25(28(37)35-38)27(24)36(18-19-5-4-14-33-16-19)41(39,40)23-11-8-21(9-12-23)20-6-2-1-3-7-20/h1-17,38H,18H2,(H,35,37) DCZIFTAWIUHEEC-UHFFFAOYSA-N 50126603 4-[(biphenyl-4-sulfonyl)-pyridin-3-ylmethyl-amino]-7-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL289604 Disintegrin and metalloproteinase domain-containing protein 17 124 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126603 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126603&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10120930 104018678 CHEMBL289604 ZINC29254370 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229502 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(nc(C)c12)-c1ccccc1)C(=O)NO InChI=1S/C27H24N6O5S/c1-18-24-25(23(27(34)31-35)16-29-26(24)33(30-18)20-8-4-3-5-9-20)32(17-19-7-6-14-28-15-19)39(36,37)22-12-10-21(38-2)11-13-22/h3-16,35H,17H2,1-2H3,(H,31,34) KWWNNPAPYSJGQH-UHFFFAOYSA-N 50126609 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL429336 Disintegrin and metalloproteinase domain-containing protein 17 138 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126609&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9808391 104018684 CHEMBL429336 ZINC01489872 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229504 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(C)C)C(=O)NO InChI=1S/C27H27N3O5S/c1-18(2)22-10-7-11-23-25(22)28-16-24(27(31)29-32)26(23)30(17-19-8-5-4-6-9-19)36(33,34)21-14-12-20(35-3)13-15-21/h4-16,18,32H,17H2,1-3H3,(H,29,31) JMTSRJRSBJJBGP-UHFFFAOYSA-N 50126607 4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-8-isopropylquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-isopropyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL36999 Disintegrin and metalloproteinase domain-containing protein 17 589 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126607&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10278934 104018682 CHEMBL36999 ZINC13489438 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229511 COc1cccc2c(N(C)S(=O)(=O)c3ccc(OCC#CC)cc3)c(cnc12)C(=O)NO InChI=1S/C22H21N3O6S/c1-4-5-13-31-15-9-11-16(12-10-15)32(28,29)25(2)21-17-7-6-8-19(30-3)20(17)23-14-18(21)22(26)24-27/h6-12,14,27H,13H2,1-3H3,(H,24,26) DWBZTKJXPJGGSU-UHFFFAOYSA-N 50126615 4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-8-methoxyquinoline-3-carboxamide::4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-8-methoxy-quinoline-3-carboxylic acid hydroxyamide::CHEMBL288671 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126615&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9825237 104018690 CHEMBL288671 ZINC03820770 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229518 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(I)cccc12)C(=O)NO InChI=1S/C23H19IN4O5S/c1-33-16-7-9-17(10-8-16)34(31,32)28(14-15-4-3-11-25-12-15)22-18-5-2-6-20(24)21(18)26-13-19(22)23(29)27-30/h2-13,30H,14H2,1H3,(H,27,29) ZYBCZOFEUHHWME-UHFFFAOYSA-N 50126617 8-Iodo-4-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-quinoline-3-carboxylic acid hydroxyamide::CHEMBL285546::N-hydroxy-8-iodo-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)quinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 124 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126617&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9808594 104018692 CHEMBL285546 ZINC29306525 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229521 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(Br)cccc12)C(=O)NO InChI=1S/C23H19BrN4O5S/c1-33-16-7-9-17(10-8-16)34(31,32)28(14-15-4-3-11-25-12-15)22-18-5-2-6-20(24)21(18)26-13-19(22)23(29)27-30/h2-13,30H,14H2,1H3,(H,27,29) GKDAXRUOVHMLSA-UHFFFAOYSA-N 50126624 8-Bromo-4-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-quinoline-3-carboxylic acid hydroxyamide::8-bromo-N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)quinoline-3-carboxamide::CHEMBL38352 Disintegrin and metalloproteinase domain-containing protein 17 124 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126624&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10165868 104018699 CHEMBL38352 ZINC29310430 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229523 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(OC)cccc12)C(=O)NO InChI=1S/C24H22N4O6S/c1-33-17-8-10-18(11-9-17)35(31,32)28(15-16-5-4-12-25-13-16)23-19-6-3-7-21(34-2)22(19)26-14-20(23)24(29)27-30/h3-14,30H,15H2,1-2H3,(H,27,29) ZORDGSDKVXISJV-UHFFFAOYSA-N 50126623 8-Methoxy-4-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-quinoline-3-carboxylic acid hydroxyamide::CHEMBL34808::N-hydroxy-8-methoxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)quinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 226 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126623&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10141426 104018698 CHEMBL34808 ZINC01489868 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229526 CN(c1c(cnc2n(C)nc(C)c12)C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C22H20ClN5O5S/c1-13-19-20(18(22(29)26-30)12-24-21(19)27(2)25-13)28(3)34(31,32)17-10-8-16(9-11-17)33-15-6-4-14(23)5-7-15/h4-12,30H,1-3H3,(H,26,29) YMQBLRHAACUVFH-UHFFFAOYSA-N 50126612 4-{[4-(4-Chloro-phenoxy)-benzenesulfonyl]-methyl-amino}-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL286848 Disintegrin and metalloproteinase domain-containing protein 17 356 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126612&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10278729 104018687 CHEMBL286848 ZINC13489446 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229529 CCCCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2n(C)nc(C)c12)C(=O)NO InChI=1S/C20H25N5O5S/c1-5-6-11-30-14-7-9-15(10-8-14)31(28,29)25(4)18-16(20(26)23-27)12-21-19-17(18)13(2)22-24(19)3/h7-10,12,27H,5-6,11H2,1-4H3,(H,23,26) KQYGUXCNMQFLRN-UHFFFAOYSA-N 50126621 4-[(4-Butoxy-benzenesulfonyl)-methyl-amino]-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL35606 Disintegrin and metalloproteinase domain-containing protein 17 86 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126621&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44283613 104018696 CHEMBL35606 ZINC13489445 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229530 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(Cc3ccccc3)cccc12)C(=O)NO InChI=1S/C30H26N4O5S/c1-39-24-12-14-25(15-13-24)40(37,38)34(20-22-9-6-16-31-18-22)29-26-11-5-10-23(17-21-7-3-2-4-8-21)28(26)32-19-27(29)30(35)33-36/h2-16,18-19,36H,17,20H2,1H3,(H,33,35) KGVROUUAKSRCEI-UHFFFAOYSA-N 50126625 8-Benzyl-4-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-quinoline-3-carboxylic acid hydroxyamide::8-benzyl-N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)quinoline-3-carboxamide::CHEMBL35433 Disintegrin and metalloproteinase domain-containing protein 17 336 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126625&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10144091 104018700 CHEMBL35433 ZINC29306919 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229531 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2cc(ccc12)C(F)(F)F)C(=O)NO InChI=1S/C25H20F3N3O5S/c1-36-18-8-10-19(11-9-18)37(34,35)31(15-16-5-3-2-4-6-16)23-20-12-7-17(25(26,27)28)13-22(20)29-14-21(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32) RPOHBDSRTDJNFN-UHFFFAOYSA-N 50126614 4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-7-(trifluoromethyl)quinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-7-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL287823 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126614&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10165419 104018689 CHEMBL287823 ZINC29310043 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229532 COc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2c(C=C)cccc12)C(=O)NO InChI=1S/C20H19N3O5S/c1-4-13-6-5-7-16-18(13)21-12-17(20(24)22-25)19(16)23(2)29(26,27)15-10-8-14(28-3)9-11-15/h4-12,25H,1H2,2-3H3,(H,22,24) JXIIDVGEPSOIKK-UHFFFAOYSA-N 50126627 4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-8-vinyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL38106::N-hydroxy-4-(4-methoxy-N-methylphenylsulfonamido)-8-vinylquinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 205 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126627&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44283598 104018702 CHEMBL38106 ZINC13489435 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229535 CN(c1c(cnc2ccccc12)C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 InChI=1S/C22H18N4O5S/c1-26(21-18-4-2-3-5-20(18)24-14-19(21)22(27)25-28)32(29,30)17-8-6-15(7-9-17)31-16-10-12-23-13-11-16/h2-14,28H,1H3,(H,25,27) RAOAFDPXSFVLJD-UHFFFAOYSA-N 50126626 4-{Methyl-[4-(pyridin-4-yloxy)-benzenesulfonyl]-amino}-quinoline-3-carboxylic acid hydroxyamide::CHEMBL287871::N-hydroxy-4-(N-methyl-4-(pyridin-4-yloxy)phenylsulfonamido)quinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 124 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126626&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10321516 104018701 CHEMBL287871 ZINC13489441 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229537 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2onc(C)c12)C(=O)NO InChI=1S/C19H18N4O6S/c1-4-5-10-28-13-6-8-14(9-7-13)30(26,27)23(3)17-15(18(24)21-25)11-20-19-16(17)12(2)22-29-19/h6-9,11,25H,10H2,1-3H3,(H,21,24) FHAJCDXKKGQJQW-UHFFFAOYSA-N 50126601 4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-3-methylisoxazolo[5,4-b]pyridine-5-carboxamide::4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-3-methyl-isoxazolo[5,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL36309 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126601&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910544 104018676 CHEMBL36309 ZINC03924184 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229538 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2onc(C)c12)C(=O)NO InChI=1S/C21H19N5O6S/c1-13-18-19(17(20(27)24-28)11-23-21(18)32-25-13)26(12-14-4-3-9-22-10-14)33(29,30)16-7-5-15(31-2)6-8-16/h3-11,28H,12H2,1-2H3,(H,24,27) ZZVSRSRVYMQUCW-UHFFFAOYSA-N 50126613 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-isoxazolo[5,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL34418::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-3-methylisoxazolo[5,4-b]pyridine-5-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 147 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126613&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10116042 104018688 CHEMBL34418 ZINC13489442 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229552 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(F)(F)F)C(=O)NO InChI=1S/C25H20F3N3O5S/c1-36-17-10-12-18(13-11-17)37(34,35)31(15-16-6-3-2-4-7-16)23-19-8-5-9-21(25(26,27)28)22(19)29-14-20(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32) AXTUTMYETKQSJS-UHFFFAOYSA-N 50126622 4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-8-(trifluoromethyl)quinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL34411 Disintegrin and metalloproteinase domain-containing protein 17 190 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10119294 104018697 CHEMBL34411 ZINC29253427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229559 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2ccc(Br)cc12)C(=O)NO InChI=1S/C24H20BrN3O5S/c1-33-18-8-10-19(11-9-18)34(31,32)28(15-16-5-3-2-4-6-16)23-20-13-17(25)7-12-22(20)26-14-21(23)24(29)27-30/h2-14,30H,15H2,1H3,(H,27,29) JAVKQWAQQAGPFN-UHFFFAOYSA-N 50126611 4-(N-benzyl-4-methoxyphenylsulfonamido)-6-bromo-N-hydroxyquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-bromo-quinoline-3-carboxylic acid hydroxyamide::CHEMBL36191 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126611&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10143672 104018686 CHEMBL36191 ZINC29243086 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229560 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2n(C)nc(C)c12)C(=O)NO InChI=1S/C20H21N5O5S/c1-5-6-11-30-14-7-9-15(10-8-14)31(28,29)25(4)18-16(20(26)23-27)12-21-19-17(18)13(2)22-24(19)3/h7-10,12,27H,11H2,1-4H3,(H,23,26) UICCGUSKKDLVIN-UHFFFAOYSA-N 50126610 4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL289222 Disintegrin and metalloproteinase domain-containing protein 17 30 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126610&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9933083 104018685 CHEMBL289222 ZINC03924183 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229561 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(cccc12)-c1ccccc1)C(=O)NO InChI=1S/C29H24N4O5S/c1-38-22-12-14-23(15-13-22)39(36,37)33(19-20-7-6-16-30-17-20)28-25-11-5-10-24(21-8-3-2-4-9-21)27(25)31-18-26(28)29(34)32-35/h2-18,35H,19H2,1H3,(H,32,34) JRKVJTDYMGJJAK-UHFFFAOYSA-N 50126605 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-8-phenyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL290952::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-8-phenylquinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126605&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10187181 104018680 CHEMBL290952 ZINC29306629 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229562 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(cccc12)C(C)(C)C)C(=O)NO InChI=1S/C28H29N3O5S/c1-28(2,3)24-12-8-11-22-25(24)29-17-23(27(32)30-33)26(22)31(18-19-9-6-5-7-10-19)37(34,35)21-15-13-20(36-4)14-16-21/h5-17,33H,18H2,1-4H3,(H,30,32) NYEXRVCCRODWLT-UHFFFAOYSA-N 50126618 4-(N-benzyl-4-methoxyphenylsulfonamido)-8-tert-butyl-N-hydroxyquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-tert-butyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL34660 Disintegrin and metalloproteinase domain-containing protein 17 401.0 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126618&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10186288 104018693 CHEMBL34660 ZINC13489439 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231568 COc1ccc(Oc2ccc3c(NCCN([C@H](C)C(=O)NO)S3(=O)=O)c2)cc1 InChI=1S/C18H21N3O6S/c1-12(18(22)20-23)21-10-9-19-16-11-15(7-8-17(16)28(21,24)25)27-14-5-3-13(26-2)4-6-14/h3-8,11-12,19,23H,9-10H2,1-2H3,(H,20,22)/t12-/m1/s1 PFUFYTLQYUUPMX-GFCCVEGCSA-N 50127451 CHEMBL53643::N-Hydroxy-2-[7-(4-methoxy-phenoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 621 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127451 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127451&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11112302 104019342 CHEMBL53643 ZINC13518189 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231569 COc1cc(COc2ccc3c(NCCN([C@H](C(C)C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C22H29N3O7S/c1-14(2)21(22(26)24-27)25-8-7-23-19-12-16(5-6-20(19)33(25,28)29)32-13-15-9-17(30-3)11-18(10-15)31-4/h5-6,9-12,14,21,23,27H,7-8,13H2,1-4H3,(H,24,26)/t21-/m1/s1 YHQKAILNGYAYKF-OAQYLSRUSA-N 50127470 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-3-methyl-butyramide::CHEMBL295710 Disintegrin and metalloproteinase domain-containing protein 17 4000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127470&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10983665 104019361 CHEMBL295710 ZINC13518159 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231571 COC(=O)CC[C@@H](N1CCNc2cc(OCc3cc(OC)cc(OC)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C23H29N3O9S/c1-32-17-10-15(11-18(12-17)33-2)14-35-16-4-6-21-19(13-16)24-8-9-26(36(21,30)31)20(23(28)25-29)5-7-22(27)34-3/h4,6,10-13,20,24,29H,5,7-9,14H2,1-3H3,(H,25,28)/t20-/m1/s1 YGLAUESDHXXPSW-HXUWFJFHSA-N 50127464 4-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-hydroxycarbamoyl-butyric acid methyl ester::CHEMBL53123 Disintegrin and metalloproteinase domain-containing protein 17 177 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127464 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127464&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11049650 104019355 CHEMBL53123 ZINC13518169 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231573 COc1ccc2c(NCCN([C@H](C)C(=O)NO)S2(=O)=O)c1 InChI=1S/C12H17N3O5S/c1-8(12(16)14-17)15-6-5-13-10-7-9(20-2)3-4-11(10)21(15,18)19/h3-4,7-8,13,17H,5-6H2,1-2H3,(H,14,16)/t8-/m1/s1 WBMFTZHBDMFDSO-MRVPVSSYSA-N 50127476 CHEMBL54021::N-Hydroxy-2-(7-methoxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-propionamide Disintegrin and metalloproteinase domain-containing protein 17 274 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127476&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10041385 104019367 CHEMBL54021 ZINC13518112 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231578 COc1ccc2c(NCCN(CC(=O)NO)S2(=O)=O)c1 InChI=1S/C11H15N3O5S/c1-19-8-2-3-10-9(6-8)12-4-5-14(20(10,17)18)7-11(15)13-16/h2-3,6,12,16H,4-5,7H2,1H3,(H,13,15) KDIMQQWECGDHDT-UHFFFAOYSA-N 50127482 CHEMBL52815::N-Hydroxy-2-(7-methoxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-acetamide Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127482&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9948296 104019373 CHEMBL52815 ZINC13518121 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231597 CC(C)[C@@H](N1CCNc2cc(OCc3nc(C)c(C)s3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C19H26N4O5S2/c1-11(2)18(19(24)22-25)23-8-7-20-15-9-14(5-6-16(15)30(23,26)27)28-10-17-21-12(3)13(4)29-17/h5-6,9,11,18,20,25H,7-8,10H2,1-4H3,(H,22,24)/t18-/m1/s1 RNWFVTPNHGOAMY-GOSISDBHSA-N 50127459 2-[7-(4,5-Dimethyl-thiazol-2-ylmethoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-3-methyl-butyramide::CHEMBL53055 Disintegrin and metalloproteinase domain-containing protein 17 290 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127459&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11080936 104019350 CHEMBL53055 ZINC13518165 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231598 CC(C)C[C@@H](N1CCNc2cc(OCc3ccccc3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C21H27N3O5S/c1-15(2)12-19(21(25)23-26)24-11-10-22-18-13-17(8-9-20(18)30(24,27)28)29-14-16-6-4-3-5-7-16/h3-9,13,15,19,22,26H,10-12,14H2,1-2H3,(H,23,25)/t19-/m1/s1 JRXNWTIRACLYGX-LJQANCHMSA-N 50127481 2-(7-Benzyloxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-4-methyl-pentanoic acid hydroxyamide::CHEMBL431926 Disintegrin and metalloproteinase domain-containing protein 17 350 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127481&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10252311 104019372 CHEMBL431926 ZINC13518153 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231599 C[C@@H](N1CCNc2cc(ccc2S1(=O)=O)-c1ccccc1C(F)(F)F)C(=O)NO InChI=1S/C18H18F3N3O4S/c1-11(17(25)23-26)24-9-8-22-15-10-12(6-7-16(15)29(24,27)28)13-4-2-3-5-14(13)18(19,20)21/h2-7,10-11,22,26H,8-9H2,1H3,(H,23,25)/t11-/m1/s1 AWUFNEOCKCVYDD-LLVKDONJSA-N 50127463 2-[1,1-Dioxo-7-(2-trifluoromethyl-phenyl)-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL299883 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127463&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10993677 104019354 CHEMBL299883 ZINC13518183 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231600 C[C@@H](N1CCNc2cc(OCc3cc(Cl)cc(Cl)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C18H19Cl2N3O5S/c1-11(18(24)22-25)23-5-4-21-16-9-15(2-3-17(16)29(23,26)27)28-10-12-6-13(19)8-14(20)7-12/h2-3,6-9,11,21,25H,4-5,10H2,1H3,(H,22,24)/t11-/m1/s1 WIOHNTSOYPKJIX-LLVKDONJSA-N 50127483 2-[7-(3,5-Dichloro-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL52893 Disintegrin and metalloproteinase domain-containing protein 17 153 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127483&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10895808 104019374 CHEMBL52893 ZINC13518136 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231605 COc1cc(COc2ccc3c(NCCN([C@H](CC(C)C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C23H31N3O7S/c1-15(2)9-21(23(27)25-28)26-8-7-24-20-13-17(5-6-22(20)34(26,29)30)33-14-16-10-18(31-3)12-19(11-16)32-4/h5-6,10-13,15,21,24,28H,7-9,14H2,1-4H3,(H,25,27)/t21-/m1/s1 NSLCGVDBXCHQFK-OAQYLSRUSA-N 50127471 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-4-methyl-pentanoic acid hydroxyamide::CHEMBL293074 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127471&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11060081 104019362 CHEMBL293074 ZINC13518156 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231610 COc1ccc2c(NCN([C@H](C)C(=O)NO)S2(=O)=O)c1 InChI=1S/C11H15N3O5S/c1-7(11(15)13-16)14-6-12-9-5-8(19-2)3-4-10(9)20(14,17)18/h3-5,7,12,16H,6H2,1-2H3,(H,13,15)/t7-/m1/s1 FWIXCOHQTREFPI-SSDOTTSWSA-N 50127485 CHEMBL300707::N-Hydroxy-2-(6-methoxy-1,1-dioxo-3,4-dihydro-1H-1lambda*6*-benzo[1,2,4]thiadiazin-2-yl)-propionamide Disintegrin and metalloproteinase domain-containing protein 17 3100 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127485&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10913644 104019376 CHEMBL300707 ZINC13518109 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231613 COc1cc(COc2ccc3c(NCCN([C@H](CCCCN)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C23H32N4O7S/c1-32-18-11-16(12-19(13-18)33-2)15-34-17-6-7-22-20(14-17)25-9-10-27(35(22,30)31)21(23(28)26-29)5-3-4-8-24/h6-7,11-14,21,25,29H,3-5,8-10,15,24H2,1-2H3,(H,26,28)/t21-/m1/s1 TXFHRXOVMCSUEC-OAQYLSRUSA-N 50127474 6-Amino-2-[7-(3,5-dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-hexanoic acid hydroxyamide::CHEMBL51557 Disintegrin and metalloproteinase domain-containing protein 17 31 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127474&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11083152 104019365 CHEMBL51557 ZINC13518171 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231614 C[C@@H](N1CCNc2cc(Oc3ccc(cc3)[N+]([O-])=O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C17H18N4O7S/c1-11(17(22)19-23)20-9-8-18-15-10-14(6-7-16(15)29(20,26)27)28-13-4-2-12(3-5-13)21(24)25/h2-7,10-11,18,23H,8-9H2,1H3,(H,19,22)/t11-/m1/s1 KQVRGIRNMDCIEB-LLVKDONJSA-N 50127454 CHEMBL301303::N-Hydroxy-2-[7-(4-nitro-phenoxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 1200 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127454&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10884337 104019345 CHEMBL301303 ZINC13518201 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231615 C[C@@H](N1CCNc2cc(ccc2S1(=O)=O)-c1ccccc1)C(=O)NO InChI=1S/C17H19N3O4S/c1-12(17(21)19-22)20-10-9-18-15-11-14(13-5-3-2-4-6-13)7-8-16(15)25(20,23)24/h2-8,11-12,18,22H,9-10H2,1H3,(H,19,21)/t12-/m1/s1 BNTJDVFEUJBXMT-GFCCVEGCSA-N 50127480 2-(1,1-Dioxo-7-phenyl-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-propionamide::CHEMBL298635 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127480&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10067146 104019371 CHEMBL298635 ZINC13518180 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231619 ONC(=O)CN1CCNc2ccccc2S1(=O)=O InChI=1S/C10H13N3O4S/c14-10(12-15)7-13-6-5-11-8-3-1-2-4-9(8)18(13,16)17/h1-4,11,15H,5-7H2,(H,12,14) WSGAVYSGAQDOGU-UHFFFAOYSA-N 50127461 2-(1,1-Dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-N-hydroxy-acetamide::CHEMBL52129 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127461&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9903557 104019352 CHEMBL52129 ZINC13518115 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231624 COc1cc(COc2ccc3c(NCCN([C@H](C)C(=O)NO)S3(=O)=O)c2)cc(OC)c1 InChI=1S/C20H25N3O7S/c1-13(20(24)22-25)23-7-6-21-18-11-15(4-5-19(18)31(23,26)27)30-12-14-8-16(28-2)10-17(9-14)29-3/h4-5,8-11,13,21,25H,6-7,12H2,1-3H3,(H,22,24)/t13-/m1/s1 APCYYZKHCZUJGB-CYBMUJFWSA-N 50127469 2-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-N-hydroxy-propionamide::CHEMBL51658 Disintegrin and metalloproteinase domain-containing protein 17 28000 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127469&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10961382 104019360 CHEMBL51658 ZINC13518139 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231627 COC(=O)CCC[C@@H](N1CCNc2cc(OCc3cc(OC)cc(OC)c3)ccc2S1(=O)=O)C(=O)NO InChI=1S/C24H31N3O9S/c1-33-18-11-16(12-19(13-18)34-2)15-36-17-7-8-22-20(14-17)25-9-10-27(37(22,31)32)21(24(29)26-30)5-4-6-23(28)35-3/h7-8,11-14,21,25,30H,4-6,9-10,15H2,1-3H3,(H,26,29)/t21-/m1/s1 FEFNNGHDRQMMNY-OAQYLSRUSA-N 50127456 5-[7-(3,5-Dimethoxy-benzyloxy)-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl]-5-hydroxycarbamoyl-pentanoic acid methyl ester::CHEMBL52808 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127456 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127456&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11734219 104019347 CHEMBL52808 ZINC29485545 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50231636 CC(C)C[C@@H](N1CCNc2cc(O)ccc2S1(=O)=O)C(=O)NO InChI=1S/C14H21N3O5S/c1-9(2)7-12(14(19)16-20)17-6-5-15-11-8-10(18)3-4-13(11)23(17,21)22/h3-4,8-9,12,15,18,20H,5-7H2,1-2H3,(H,16,19)/t12-/m1/s1 KJGJYHSHMUFLOA-GFCCVEGCSA-N 50127478 2-(7-Hydroxy-1,1-dioxo-1,3,4,5-tetrahydro-1lambda*6*-benzo[f][1,2,5]thiadiazepin-2-yl)-4-methyl-pentanoic acid hydroxyamide::CHEMBL301157 Disintegrin and metalloproteinase domain-containing protein 17 89 ChEMBL 10.1021/jm020475w 10.7270/Q2TQ60W7 12723945 Cherney, RJ; Duan, JJ; Voss, ME; Chen, L; Wang, L; Meyer, DT; Wasserman, ZR; Hardman, KD; Liu, RQ; Covington, MB; Qian, M; Mandlekar, S; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127478&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10980832 104019369 CHEMBL301157 ZINC13518150 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234684 CCOP(=O)(N[C@H](CCC(=O)NCCc1ccccc1)C(=O)NO)c1ccc(OC)cc1 InChI=1S/C22H30N3O6P/c1-3-31-32(29,19-11-9-18(30-2)10-12-19)25-20(22(27)24-28)13-14-21(26)23-16-15-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26)(H,24,27)(H,25,29)/t20-,32?/m1/s1 IPBVPRHDESNKFG-FTHRPBJHSA-N 50129019 CHEMBL64571::ethyl N-{(1R)-4-(2-phentl-ethyl)-amino-1-[(hydroxyamino)carbonyl]-4-oxobutyl}-P-(4-methoxyphenyl)phosphonamidoate Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/s0960-894x(03)00292-0 10.7270/Q2KW5FFZ 12781187 Sawa, M; Kurokawa, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129019&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44304112 104020691 CHEMBL64571 ZINC13490337 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234689 CCOP(=O)(N[C@@H](CC(C)C)C(=O)NO)c1ccc(OC)cc1 InChI=1S/C15H25N2O5P/c1-5-22-23(20,13-8-6-12(21-4)7-9-13)17-14(10-11(2)3)15(18)16-19/h6-9,11,14,19H,5,10H2,1-4H3,(H,16,18)(H,17,20)/t14-,23?/m0/s1 KTCRMROJXXSPQJ-JRQMZCAUSA-N 50129021 CHEMBL291361::ethyl N-(S)-1-(hydroxyamino)-4-methyl-1-oxopentan-2-yl-P-(4-methoxyphenyl)phosphonamidate::ethyl N-{(1s)-1-[(hydroxyamino)carbonyl]-3-methylbutyl}-P-(4-methoxyphenyl)phosphonamidoate Disintegrin and metalloproteinase domain-containing protein 17 76 ChEMBL 10.1016/s0960-894x(03)00292-0 10.7270/Q2KW5FFZ 12781187 Sawa, M; Kurokawa, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44304355 104020693 CHEMBL291361 ZINC26162518 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234690 CCOP(=O)(N[C@@H](CCC(=O)NCCc1ccccc1)C(=O)NO)c1ccc(OC)cc1 InChI=1S/C22H30N3O6P/c1-3-31-32(29,19-11-9-18(30-2)10-12-19)25-20(22(27)24-28)13-14-21(26)23-16-15-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26)(H,24,27)(H,25,29)/t20-,32?/m0/s1 IPBVPRHDESNKFG-QIFAOCFZSA-N 50129022 CHEMBL291387::ethyl N-{(1s)-4-(2-phentl-ethyl)-amino-1-[(hydroxyamino)carbonyl]-4-oxobutyl}-P-(4-methoxyphenyl)phosphonamidoate Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/s0960-894x(03)00292-0 10.7270/Q2KW5FFZ 12781187 Sawa, M; Kurokawa, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129022&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44304111 104020694 CHEMBL291387 ZINC84462409 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234692 CCOP(=O)(N[C@H](CC(C)C)C(=O)NO)c1ccc(OC)cc1 InChI=1S/C15H25N2O5P/c1-5-22-23(20,13-8-6-12(21-4)7-9-13)17-14(10-11(2)3)15(18)16-19/h6-9,11,14,19H,5,10H2,1-4H3,(H,16,18)(H,17,20)/t14-,23?/m1/s1 KTCRMROJXXSPQJ-PDNQZYNLSA-N 50129020 CHEMBL59692::ethyl N-{(1R)-1-[(hydroxyamino)carbonyl]-3-methylbutyl}-P-(4-methoxyphenyl)phosphonamidoate Disintegrin and metalloproteinase domain-containing protein 17 5.1 ChEMBL 10.1016/s0960-894x(03)00292-0 10.7270/Q2KW5FFZ 12781187 Sawa, M; Kurokawa, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129020&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10088847 104020692 CHEMBL59692 ZINC13490335 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234699 Cc1cc(COc2ccc(cc2)N2CC[C@H]([C@H](NC(=O)c3ccccc3)C(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C30H28N4O5/c1-19-17-21(24-9-5-6-10-26(24)31-19)18-39-23-13-11-22(12-14-23)34-16-15-25(30(34)37)27(29(36)33-38)32-28(35)20-7-3-2-4-8-20/h2-14,17,25,27,38H,15-16,18H2,1H3,(H,32,35)(H,33,36)/t25-,27+/m1/s1 OWZWNKSSYNZLEH-VPUSJEBWSA-N 50129036 CHEMBL302455::N-(((S)-Hydroxycarbamoyl)-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-methyl)-benzamide Disintegrin and metalloproteinase domain-containing protein 17 9100 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129036&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9936625 104020698 CHEMBL302455 ZINC26172333 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234700 CCC[C@@H](C(=O)NO)[C@@]1(N)CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H30N4O4/c1-3-6-22(24(31)29-33)26(27)13-14-30(25(26)32)19-9-11-20(12-10-19)34-16-18-15-17(2)28-23-8-5-4-7-21(18)23/h4-5,7-12,15,22,33H,3,6,13-14,16,27H2,1-2H3,(H,29,31)/t22-,26-/m0/s1 JTEKRZIXTMGGJR-NVQXNPDNSA-N 50129037 (R)-2-{(S)-3-Amino-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-pentanoic acid hydroxyamide::CHEMBL418476 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129037&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9934052 104020699 CHEMBL418476 ZINC13490355 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234706 COC(=O)N[C@@H]([C@H]1CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H26N4O6/c1-15-13-16(19-5-3-4-6-21(19)26-15)14-35-18-9-7-17(8-10-18)29-12-11-20(24(29)31)22(23(30)28-33)27-25(32)34-2/h3-10,13,20,22,33H,11-12,14H2,1-2H3,(H,27,32)(H,28,30)/t20-,22+/m1/s1 SBXPRGGYMRGODQ-IRLDBZIGSA-N 50129040 (((S)-Hydroxycarbamoyl)-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-methyl)-carbamic acid methyl ester::CHEMBL60373 Disintegrin and metalloproteinase domain-containing protein 17 2650 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129040 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129040&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9805079 104020702 CHEMBL60373 ZINC13490350 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234711 C[C@@H]([C@H]1CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C24H25N3O4/c1-15-13-17(21-5-3-4-6-22(21)25-15)14-31-19-9-7-18(8-10-19)27-12-11-20(24(27)29)16(2)23(28)26-30/h3-10,13,16,20,30H,11-12,14H2,1-2H3,(H,26,28)/t16-,20+/m0/s1 DHZSRYYUAYXLLX-OXJNMPFZSA-N 50129042 (S)-N-Hydroxy-2-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-propionamide::CHEMBL63272 Disintegrin and metalloproteinase domain-containing protein 17 1570 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129042&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9953861 104020704 CHEMBL63272 ZINC13490340 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234714 Cc1cc(COc2ccc(cc2)N2CC[C@](N)(CC(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C23H24N4O4/c1-15-12-16(19-4-2-3-5-20(19)25-15)14-31-18-8-6-17(7-9-18)27-11-10-23(24,22(27)29)13-21(28)26-30/h2-9,12,30H,10-11,13-14,24H2,1H3,(H,26,28)/t23-/m0/s1 LZYMCZBJTXXZLJ-QHCPKHFHSA-N 50129039 2-{(S)-3-Amino-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-N-hydroxy-acetamide::CHEMBL302002 Disintegrin and metalloproteinase domain-containing protein 17 4800 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129039&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9802219 104020701 CHEMBL302002 ZINC13490351 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234715 C[C@H](C(=O)NO)[C@@]1(N)CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C24H26N4O4/c1-15-13-17(20-5-3-4-6-21(20)26-15)14-32-19-9-7-18(8-10-19)28-12-11-24(25,23(28)30)16(2)22(29)27-31/h3-10,13,16,31H,11-12,14,25H2,1-2H3,(H,27,29)/t16-,24+/m1/s1 OUOMLZAHOSXYHR-GYCJOSAFSA-N 50129044 (S)-2-{(S)-3-Amino-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-N-hydroxy-propionamide::CHEMBL305163 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129044&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9932632 104020706 CHEMBL305163 ZINC13490352 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50234721 CCCCOC(=O)N[C@@H]([C@H]1CCN(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C28H32N4O6/c1-3-4-15-37-28(35)30-25(26(33)31-36)23-13-14-32(27(23)34)20-9-11-21(12-10-20)38-17-19-16-18(2)29-24-8-6-5-7-22(19)24/h5-12,16,23,25,36H,3-4,13-15,17H2,1-2H3,(H,30,35)(H,31,33)/t23-,25+/m1/s1 RGHQIKPHUVHVFH-NOZRDPDXSA-N 50129048 (((S)-Hydroxycarbamoyl)-{(R)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-2-oxo-pyrrolidin-3-yl}-methyl)-carbamic acid butyl ester::CHEMBL417212 Disintegrin and metalloproteinase domain-containing protein 17 6830 ChEMBL 10.1016/s0960-894x(03)00313-5 10.7270/Q2G73D3T 12781190 Duan, JJ; Lu, Z; Xue, CB; He, X; Seng, JL; Roderick, JJ; Wasserman, ZR; Liu, RQ; Covington, MB; Magolda, RL; Newton, RC; Trzaskos, JM; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129048&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9892889 104020710 CHEMBL417212 ZINC13490348 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229572 CN(c1c(cnc2n(C)nc(C)c12)C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 InChI=1S/C21H20N6O5S/c1-13-18-19(17(21(28)25-29)12-23-20(18)26(2)24-13)27(3)33(30,31)16-6-4-14(5-7-16)32-15-8-10-22-11-9-15/h4-12,29H,1-3H3,(H,25,28) XQRSTZJAXGSSTI-UHFFFAOYSA-N 50126600 1,3-Dimethyl-4-{methyl-[4-(pyridin-4-yloxy)-benzenesulfonyl]-amino}-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL38180 Disintegrin and metalloproteinase domain-containing protein 17 >100 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126600&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10162155 104018675 CHEMBL38180 ZINC13489447 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229574 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2c(Br)cccc12)C(=O)NO InChI=1S/C21H18BrN3O5S/c1-3-4-12-30-14-8-10-15(11-9-14)31(28,29)25(2)20-16-6-5-7-18(22)19(16)23-13-17(20)21(26)24-27/h5-11,13,27H,12H2,1-2H3,(H,24,26) RRUNLAIBQVECGY-UHFFFAOYSA-N 50126632 8-Bromo-4-[(4-but-2-ynyloxy-benzenesulfonyl)-methyl-amino]-quinoline-3-carboxylic acid hydroxyamide::8-bromo-4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxyquinoline-3-carboxamide::CHEMBL35989 Disintegrin and metalloproteinase domain-containing protein 17 82 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126632&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9892336 104018707 CHEMBL35989 ZINC03820771 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229577 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2snc(C)c12)C(=O)NO InChI=1S/C19H18N4O5S2/c1-4-5-10-28-13-6-8-14(9-7-13)30(26,27)23(3)17-15(18(24)21-25)11-20-19-16(17)12(2)22-29-19/h6-9,11,25H,10H2,1-3H3,(H,21,24) ZAXFGRVMMQJZLL-UHFFFAOYSA-N 50126616 4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-3-methyl-isothiazolo[5,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL417144 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126616&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9933259 104018691 CHEMBL417144 ZINC01549027 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229582 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2ccc(cc12)C(F)(F)F)C(=O)NO InChI=1S/C25H20F3N3O5S/c1-36-18-8-10-19(11-9-18)37(34,35)31(15-16-5-3-2-4-6-16)23-20-13-17(25(26,27)28)7-12-22(20)29-14-21(23)24(32)30-33/h2-14,33H,15H2,1H3,(H,30,32) BYFPJSOGSJVRJE-UHFFFAOYSA-N 50126631 4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-6-(trifluoromethyl)quinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-6-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL36021 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126631&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10165420 104018706 CHEMBL36021 ZINC29242700 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229583 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(cccc12)-c1cccs1)C(=O)NO InChI=1S/C27H22N4O5S2/c1-36-19-9-11-20(12-10-19)38(34,35)31(17-18-5-3-13-28-15-18)26-22-7-2-6-21(24-8-4-14-37-24)25(22)29-16-23(26)27(32)30-33/h2-16,33H,17H2,1H3,(H,30,32) XPLPBRFYVPFHDL-UHFFFAOYSA-N 50126602 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-8-thiophen-2-yl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL37788::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-8-(thiophen-2-yl)quinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 161 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126602&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10209314 104018677 CHEMBL37788 ZINC03919991 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229587 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2c(C)cccc12)C(=O)NO InChI=1S/C25H23N3O5S/c1-17-7-6-10-21-23(17)26-15-22(25(29)27-30)24(21)28(16-18-8-4-3-5-9-18)34(31,32)20-13-11-19(33-2)12-14-20/h3-15,30H,16H2,1-2H3,(H,27,29) JFQFSHSHMHJPSW-UHFFFAOYSA-N 50126633 4-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-8-methylquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-methyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL289411 Disintegrin and metalloproteinase domain-containing protein 17 627 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126633&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10205886 104018708 CHEMBL289411 ZINC13489436 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229593 Cc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2cc(ccc12)C(F)(F)F)C(=O)NO InChI=1S/C24H19F3N4O4S/c1-15-4-7-18(8-5-15)36(34,35)31(14-16-3-2-10-28-12-16)22-19-9-6-17(24(25,26)27)11-21(19)29-13-20(22)23(32)30-33/h2-13,33H,14H2,1H3,(H,30,32) NKZQXGVLDOUMQF-UHFFFAOYSA-N 50126608 4-[Pyridin-3-ylmethyl-(toluene-4-sulfonyl)-amino]-7-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL34666 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126608&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10118633 104018683 CHEMBL34666 ZINC13489440 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229600 CCc1cccc2c(N(Cc3ccccc3)S(=O)(=O)c3ccc(OC)cc3)c(cnc12)C(=O)NO InChI=1S/C26H25N3O5S/c1-3-19-10-7-11-22-24(19)27-16-23(26(30)28-31)25(22)29(17-18-8-5-4-6-9-18)35(32,33)21-14-12-20(34-2)13-15-21/h4-16,31H,3,17H2,1-2H3,(H,28,30) OMMFNEZCURCLPN-UHFFFAOYSA-N 50126604 4-(N-benzyl-4-methoxyphenylsulfonamido)-8-ethyl-N-hydroxyquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-8-ethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL290948 Disintegrin and metalloproteinase domain-containing protein 17 314 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126604 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126604&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10141270 104018679 CHEMBL290948 ZINC13489437 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229601 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(ncc12)-c1ccccc1)C(=O)NO InChI=1S/C26H22N6O5S/c1-37-20-9-11-21(12-10-20)38(35,36)31(17-18-6-5-13-27-14-18)24-22-16-29-32(19-7-3-2-4-8-19)25(22)28-15-23(24)26(33)30-34/h2-16,34H,17H2,1H3,(H,30,33) GTRSMAWFAMXNCF-UHFFFAOYSA-N 50126629 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL33980 Disintegrin and metalloproteinase domain-containing protein 17 435 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126629&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10120586 104018704 CHEMBL33980 ZINC29307231 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229608 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2cc(ccc12)C(F)(F)F)C(=O)NO InChI=1S/C24H19F3N4O5S/c1-36-17-5-7-18(8-6-17)37(34,35)31(14-15-3-2-10-28-12-15)22-19-9-4-16(24(25,26)27)11-21(19)29-13-20(22)23(32)30-33/h2-13,33H,14H2,1H3,(H,30,32) NVQUYHFBHXGQLL-UHFFFAOYSA-N 50126620 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-7-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL287820::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-7-(trifluoromethyl)quinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126620&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10230286 104018695 CHEMBL287820 ZINC01489870 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229610 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2n(C)nc(C)c12)C(=O)NO InChI=1S/C22H22N6O5S/c1-14-19-20(18(22(29)26-30)12-24-21(19)27(2)25-14)28(13-15-5-4-10-23-11-15)34(31,32)17-8-6-16(33-3)7-9-17/h4-12,30H,13H2,1-3H3,(H,26,29) TVRLHUWRJSTBAB-UHFFFAOYSA-N 50126630 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL288670 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126630&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10184457 104018705 CHEMBL288670 ZINC00584234 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229612 CN(c1c(cnc2n(C)nc(C)c12)C(=O)NO)S(=O)(=O)c1ccc(F)cc1 InChI=1S/C16H16FN5O4S/c1-9-13-14(12(16(23)20-24)8-18-15(13)21(2)19-9)22(3)27(25,26)11-6-4-10(17)5-7-11/h4-8,24H,1-3H3,(H,20,23) UQNGOLQNCCYWJR-UHFFFAOYSA-N 50126628 4-[(4-Fluoro-benzenesulfonyl)-methyl-amino]-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL35059 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126628&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44283938 104018703 CHEMBL35059 ZINC13489444 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50229566 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(cnc2cc(Br)ccc12)C(=O)NO InChI=1S/C24H20BrN3O5S/c1-33-18-8-10-19(11-9-18)34(31,32)28(15-16-5-3-2-4-6-16)23-20-12-7-17(25)13-22(20)26-14-21(23)24(29)27-30/h2-14,30H,15H2,1H3,(H,27,29) DCWUWJBJOHDJGB-UHFFFAOYSA-N 50126619 4-(N-benzyl-4-methoxyphenylsulfonamido)-7-bromo-N-hydroxyquinoline-3-carboxamide::4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-7-bromo-quinoline-3-carboxylic acid hydroxyamide::CHEMBL418053 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/s0960-894x(03)00127-6 10.7270/Q29W0DW0 12668018 Zask, A; Gu, Y; Albright, JD; Du, X; Hogan, M; Levin, JI; Chen, JM; Killar, LM; Sung, A; DiJoseph, JF; Sharr, MA; Roth, CE; Skala, S; Jin, G; Cowling, R; Mohler, KM; Barone, D; Black, R; March, C; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126619&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10119730 104018694 CHEMBL418053 ZINC29309746 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50260030 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@H]2OC(C)(C)O[C@H]2[C@H](O)[C@@H]1C(=O)NO InChI=1S/C19H24N2O8S/c1-4-5-10-27-12-6-8-13(9-7-12)30(25,26)21-11-14-17(29-19(2,3)28-14)16(22)15(21)18(23)20-24/h6-9,14-17,22,24H,10-11H2,1-3H3,(H,20,23)/t14-,15-,16-,17-/m1/s1 CFNLVCZTXBNJGL-QBPKDAKJSA-N 50141576 (3aR,6R,7R,7aS)-5-(4-But-2-ynyloxy-benzenesulfonyl)-7-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-6-carboxylic acid hydroxyamide::CHEMBL288664 Disintegrin and metalloproteinase domain-containing protein 17 0.570000 ChEMBL 10.1016/j.bmcl.2003.12.091 10.7270/Q2KS6QZB 15006405 Tsukida, T; Moriyama, H; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141576 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141576&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10388523 104031035 CHEMBL288664 ZINC29326010 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50260034 CO[C@H]1[C@H](O)[C@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C17H22N2O8S/c1-3-4-9-27-11-5-7-12(8-6-11)28(24,25)19-10-13(20)15(21)16(26-2)14(19)17(22)18-23/h5-8,13-16,20-21,23H,9-10H2,1-2H3,(H,18,22)/t13-,14-,15-,16-/m1/s1 WZZROHGXDJBEMY-KLHDSHLOSA-N 50141575 (2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-4,5-dihydroxy-3-methoxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL291264 Disintegrin and metalloproteinase domain-containing protein 17 1.9 ChEMBL 10.1016/j.bmcl.2003.12.091 10.7270/Q2KS6QZB 15006405 Tsukida, T; Moriyama, H; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141575 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141575&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44286674 104031034 CHEMBL291264 ZINC29340192 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50260035 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@H]2OC(C)(C)O[C@@H]2[C@@H]1C(=O)NO InChI=1S/C19H24N2O8S/c1-4-5-10-27-12-6-8-13(9-7-12)30(25,26)21-11-14(22)16-17(15(21)18(23)20-24)29-19(2,3)28-16/h6-9,14-17,22,24H,10-11H2,1-3H3,(H,20,23)/t14-,15-,16-,17-/m1/s1 RFJSQAZBRWXDMS-QBPKDAKJSA-N 50141578 (3aR,4R,7R,7aR)-5-(4-But-2-ynyloxy-benzenesulfonyl)-7-hydroxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-4-carboxylic acid hydroxyamide::CHEMBL288843 Disintegrin and metalloproteinase domain-containing protein 17 1.9 ChEMBL 10.1016/j.bmcl.2003.12.091 10.7270/Q2KS6QZB 15006405 Tsukida, T; Moriyama, H; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141578 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141578&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44286654 104031037 CHEMBL288843 ZINC29325398 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50260037 CO[C@H]1[C@@H]2OC(C)(C)O[C@@H]2CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C20H26N2O8S/c1-5-6-11-28-13-7-9-14(10-8-13)31(25,26)22-12-15-17(30-20(2,3)29-15)18(27-4)16(22)19(23)21-24/h7-10,15-18,24H,11-12H2,1-4H3,(H,21,23)/t15-,16-,17-,18-/m1/s1 NXWFYCXTAINJMY-BRSBDYLESA-N 50141574 (3aR,6R,7R,7aR)-5-(4-But-2-ynyloxy-benzenesulfonyl)-7-methoxy-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridine-6-carboxylic acid hydroxyamide::CHEMBL41821 Disintegrin and metalloproteinase domain-containing protein 17 0.840000 ChEMBL 10.1016/j.bmcl.2003.12.091 10.7270/Q2KS6QZB 15006405 Tsukida, T; Moriyama, H; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141574&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44286663 104031033 CHEMBL41821 ZINC29338506 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50260042 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO InChI=1S/C16H20N2O8S/c1-2-3-8-26-10-4-6-11(7-5-10)27(24,25)18-9-12(19)14(20)15(21)13(18)16(22)17-23/h4-7,12-15,19-21,23H,8-9H2,1H3,(H,17,22)/t12-,13-,14-,15-/m1/s1 WSWMIGCNSWBCNT-KBUPBQIOSA-N 50141577 (2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL43087 Disintegrin and metalloproteinase domain-containing protein 17 0.530000 ChEMBL 10.1016/j.bmcl.2003.12.091 10.7270/Q2KS6QZB 15006405 Tsukida, T; Moriyama, H; Inoue, Y; Kondo, H; Yoshino, K; Nishimura, S Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11246575 104031036 CHEMBL43087 ZINC13560275 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50249353 Clc1ccc2oc(cc2c1)C(=O)NC[C@]1(NC(=O)NC1=O)c1ccccc1 InChI=1S/C19H14ClN3O4/c20-13-6-7-14-11(8-13)9-15(27-14)16(24)21-10-19(12-4-2-1-3-5-12)17(25)22-18(26)23-19/h1-9H,10H2,(H,21,24)(H2,22,23,25,26)/t19-/m0/s1 KDEHHSHGVKUYEZ-IBGZPJMESA-N 50033819 CHEMBL3358153 Disintegrin and metalloproteinase domain-containing protein 17 5400 ChEMBL 10.1021/jm501522n 10.7270/Q2K35W85 25415648 Durham, TB; Klimkowski, VJ; Rito, CJ; Marimuthu, J; Toth, JL; Liu, C; Durbin, JD; Stout, SL; Adams, L; Swearingen, C; Lin, C; Chambers, MG; Thirunavukkarasu, K; Wiley, MR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033819&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 118722686 103942067 CHEMBL3358153 ZINC04533909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50249399 Clc1ccc2oc(cc2c1)C(=O)NC[C@]1(NC(=O)NC1=O)c1nccs1 InChI=1S/C16H11ClN4O4S/c17-9-1-2-10-8(5-9)6-11(25-10)12(22)19-7-16(14-18-3-4-26-14)13(23)20-15(24)21-16/h1-6H,7H2,(H,19,22)(H2,20,21,23,24)/t16-/m1/s1 LBVBVIKJOWWVJX-MRXNPFEDSA-N 50033805 CHEMBL3358155 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/jm501522n 10.7270/Q2K35W85 25415648 Durham, TB; Klimkowski, VJ; Rito, CJ; Marimuthu, J; Toth, JL; Liu, C; Durbin, JD; Stout, SL; Adams, L; Swearingen, C; Lin, C; Chambers, MG; Thirunavukkarasu, K; Wiley, MR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033805&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 3PU 4WKE 86287515 103942053 CHEMBL3358155 ZINC01659434 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50249400 Cn1ccnc1[C@]1(CNC(=O)c2cc3cc(ccc3o2)C(F)(F)F)NC(=O)NC1=O InChI=1S/C18H14F3N5O4/c1-26-5-4-22-14(26)17(15(28)24-16(29)25-17)8-23-13(27)12-7-9-6-10(18(19,20)21)2-3-11(9)30-12/h2-7H,8H2,1H3,(H,23,27)(H2,24,25,28,29)/t17-/m0/s1 PDBQNZHFRVAZBC-KRWDZBQOSA-N 50033808 CHEMBL3358158 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/jm501522n 10.7270/Q2K35W85 25415648 Durham, TB; Klimkowski, VJ; Rito, CJ; Marimuthu, J; Toth, JL; Liu, C; Durbin, JD; Stout, SL; Adams, L; Swearingen, C; Lin, C; Chambers, MG; Thirunavukkarasu, K; Wiley, MR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50033808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50033808&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 101910871 103942056 CHEMBL3358158 ZINC13602504 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50249401 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(F)cc2Cl)cc1 InChI=1S/C20H22ClFN2O6S/c1-20(26)9-2-10-24(18(20)19(25)23-27)31(28,29)16-7-5-15(6-8-16)30-12-13-3-4-14(22)11-17(13)21/h3-8,11,18,26-27H,2,9-10,12H2,1H3,(H,23,25)/t18-,20+/m0/s1 LTVIJEFEZVFIST-AZUAARDMSA-N 50168737 (2R,3R)-1-[4-(2-Chloro-4-fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187092 Disintegrin and metalloproteinase domain-containing protein 17 7.0 ChEMBL 10.1021/jm501522n 10.7270/Q2K35W85 25415648 Durham, TB; Klimkowski, VJ; Rito, CJ; Marimuthu, J; Toth, JL; Liu, C; Durbin, JD; Stout, SL; Adams, L; Swearingen, C; Lin, C; Chambers, MG; Thirunavukkarasu, K; Wiley, MR Eli Lilly and Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168737&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395506 104053698 CHEMBL187092 ZINC11688142 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275821 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2cc(ccc2N(CC1C(=O)NO)C(C)=O)N1CCN(C)CC1 InChI=1S/C27H33N5O6S/c1-4-5-16-38-23-7-9-24(10-8-23)39(36,37)32-18-21-17-22(30-14-12-29(3)13-15-30)6-11-25(21)31(20(2)33)19-26(32)27(34)28-35/h6-11,17,26,35H,12-16,18-19H2,1-3H3,(H,28,34) BWBHMVGDPUEYMT-UHFFFAOYSA-N 50150248 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-(4-methyl-piperazin-1-yl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL183735 Disintegrin and metalloproteinase domain-containing protein 17 92 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150248&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393217 104038739 CHEMBL183735 ZINC28377186 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275826 CNCc1ccc2CN(C(CN(C(C)=O)c2c1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C24H28N4O6S/c1-4-5-12-34-20-8-10-21(11-9-20)35(32,33)28-15-19-7-6-18(14-25-3)13-22(19)27(17(2)29)16-23(28)24(30)26-31/h6-11,13,23,25,31H,12,14-16H2,1-3H3,(H,26,30) ISBRGXFRKARDDV-UHFFFAOYSA-N 50150244 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-methylaminomethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL184168 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150244&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393328 104038735 CHEMBL184168 ZINC28381099 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275829 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccc(CN(C)C)cc2N(CC1C(=O)NO)C(C)=O InChI=1S/C25H30N4O6S/c1-5-6-13-35-21-9-11-22(12-10-21)36(33,34)29-16-20-8-7-19(15-27(3)4)14-23(20)28(18(2)30)17-24(29)25(31)26-32/h7-12,14,24,32H,13,15-17H2,1-4H3,(H,26,31) XMKAMECIIHUBSZ-UHFFFAOYSA-N 50150254 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-dimethylaminomethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL183228 Disintegrin and metalloproteinase domain-containing protein 17 18 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150254 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150254&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393295 104038745 CHEMBL183228 ZINC28350341 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275831 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1ccco1 InChI=1S/C25H23N3O7S/c1-2-3-14-34-19-10-12-20(13-11-19)36(32,33)28-16-18-7-4-5-8-21(18)27(17-22(28)24(29)26-31)25(30)23-9-6-15-35-23/h4-13,15,22,31H,14,16-17H2,1H3,(H,26,29) IVXFVTBAZBQGPK-UHFFFAOYSA-N 50150253 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(furan-2-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL366257 Disintegrin and metalloproteinase domain-containing protein 17 33 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150253 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150253&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9827635 104038744 CHEMBL366257 ZINC28376760 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275832 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2cc(ccc2N(CC1C(=O)NO)C(C)=O)N(C)C InChI=1S/C24H28N4O6S/c1-5-6-13-34-20-8-10-21(11-9-20)35(32,33)28-15-18-14-19(26(3)4)7-12-22(18)27(17(2)29)16-23(28)24(30)25-31/h7-12,14,23,31H,13,15-16H2,1-4H3,(H,25,30) BNLNSLPPTDOCGX-UHFFFAOYSA-N 50150252 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-dimethylamino-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL184007 Disintegrin and metalloproteinase domain-containing protein 17 197 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150252 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150252&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393266 104038743 CHEMBL184007 ZINC28382008 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275834 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2cc(NCCc3ccccn3)ccc2N(CC1C(=O)NO)C(C)=O InChI=1S/C29H31N5O6S/c1-3-4-17-40-25-9-11-26(12-10-25)41(38,39)34-19-22-18-24(31-16-14-23-7-5-6-15-30-23)8-13-27(22)33(21(2)35)20-28(34)29(36)32-37/h5-13,15,18,28,31,37H,14,16-17,19-20H2,1-2H3,(H,32,36) MJYIMHGWKZRGTK-UHFFFAOYSA-N 50150251 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-(2-pyridin-2-yl-ethylamino)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL184745 Disintegrin and metalloproteinase domain-containing protein 17 49 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150251 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150251&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393261 104038742 CHEMBL184745 ZINC28370516 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275837 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2cc(ccc2N(CC1C(=O)NO)C(C)=O)N1CCOCC1 InChI=1S/C26H30N4O7S/c1-3-4-13-37-22-6-8-23(9-7-22)38(34,35)30-17-20-16-21(28-11-14-36-15-12-28)5-10-24(20)29(19(2)31)18-25(30)26(32)27-33/h5-10,16,25,33H,11-15,17-18H2,1-2H3,(H,27,32) FKTVHOWSOLKJIV-UHFFFAOYSA-N 50150256 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-morpholin-4-yl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL363758 Disintegrin and metalloproteinase domain-containing protein 17 130 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150256&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393239 104038747 CHEMBL363758 ZINC28372254 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275840 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccc(CNC(C)=O)cc2N(CC1C(=O)NO)C(C)=O InChI=1S/C25H28N4O7S/c1-4-5-12-36-21-8-10-22(11-9-21)37(34,35)29-15-20-7-6-19(14-26-17(2)30)13-23(20)28(18(3)31)16-24(29)25(32)27-33/h6-11,13,24,33H,12,14-16H2,1-3H3,(H,26,30)(H,27,32) YXMRNZNQTDDTSA-UHFFFAOYSA-N 50150249 1-Acetyl-8-(acetylamino-methyl)-4-(4-but-2-ynyloxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL183732 Disintegrin and metalloproteinase domain-containing protein 17 31 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150249 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150249&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393358 104038740 CHEMBL183732 ZINC28382178 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275841 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1cccnc1 InChI=1S/C26H24N4O6S/c1-2-3-15-36-21-10-12-22(13-11-21)37(34,35)30-17-20-7-4-5-9-23(20)29(18-24(30)25(31)28-33)26(32)19-8-6-14-27-16-19/h4-14,16,24,33H,15,17-18H2,1H3,(H,28,31) UCKDGXYIQSPPDL-UHFFFAOYSA-N 50150257 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(pyridine-3-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL365892 Disintegrin and metalloproteinase domain-containing protein 17 89 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150257&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393383 104038748 CHEMBL365892 ZINC28381040 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275845 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2cc(OCCc3ccccc3)ccc2N(CC1C(=O)NO)C(C)=O InChI=1S/C30H31N3O7S/c1-3-4-17-39-25-10-13-27(14-11-25)41(37,38)33-20-24-19-26(40-18-16-23-8-6-5-7-9-23)12-15-28(24)32(22(2)34)21-29(33)30(35)31-36/h5-15,19,29,36H,16-18,20-21H2,1-2H3,(H,31,35) FSJPBIIVCZKHRS-UHFFFAOYSA-N 50150255 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-phenethyloxy-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL184119 Disintegrin and metalloproteinase domain-containing protein 17 36 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150255&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10393391 104038746 CHEMBL184119 ZINC28380509 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275848 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccc(CO)cc2N(CC1C(=O)NO)C(C)=O InChI=1S/C23H25N3O7S/c1-3-4-11-33-19-7-9-20(10-8-19)34(31,32)26-13-18-6-5-17(15-27)12-21(18)25(16(2)28)14-22(26)23(29)24-30/h5-10,12,22,27,30H,11,13-15H2,1-2H3,(H,24,29) JQGYJNKTRDAQCV-UHFFFAOYSA-N 50150246 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-hydroxymethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::1-acetyl-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-8-(hydroxymethyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxamide::CHEMBL183924 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150246&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10435554 104038737 CHEMBL183924 ZINC28378894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275849 CNC(=O)c1ccc2CN(C(CN(C(C)=O)c2c1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C24H26N4O7S/c1-4-5-12-35-19-8-10-20(11-9-19)36(33,34)28-14-18-7-6-17(23(30)25-3)13-21(18)27(16(2)29)15-22(28)24(31)26-32/h6-11,13,22,32H,12,14-15H2,1-3H3,(H,25,30)(H,26,31) OUIRYNJKZCTIHG-UHFFFAOYSA-N 50150258 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3,8-dicarboxylic acid 3-hydroxyamide 8-methylamide::CHEMBL184943 Disintegrin and metalloproteinase domain-containing protein 17 41 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150258 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150258&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393394 104038749 CHEMBL184943 ZINC28376000 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275851 COCC(=O)N1CC(N(Cc2ccccc12)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C23H25N3O7S/c1-3-4-13-33-18-9-11-19(12-10-18)34(30,31)26-14-17-7-5-6-8-20(17)25(22(27)16-32-2)15-21(26)23(28)24-29/h5-12,21,29H,13-16H2,1-2H3,(H,24,28) VVCQPDVATXLSSI-UHFFFAOYSA-N 50150250 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(2-methoxy-acetyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL183404 Disintegrin and metalloproteinase domain-containing protein 17 81 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150250 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150250&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393414 104038741 CHEMBL183404 ZINC13917088 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275852 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(=O)c1cnccn1 InChI=1S/C25H23N5O6S/c1-2-3-14-36-19-8-10-20(11-9-19)37(34,35)30-16-18-6-4-5-7-22(18)29(17-23(30)24(31)28-33)25(32)21-15-26-12-13-27-21/h4-13,15,23,33H,14,16-17H2,1H3,(H,28,31) KUDDIXBNWHQPDJ-UHFFFAOYSA-N 50150247 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(pyrazine-2-carbonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL185375 Disintegrin and metalloproteinase domain-containing protein 17 69 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150247 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150247&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393214 104038738 CHEMBL185375 ZINC28376414 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275854 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccc(CN3CCNCC3)cc2N(CC1C(=O)NO)C(C)=O InChI=1S/C27H33N5O6S/c1-3-4-15-38-23-7-9-24(10-8-23)39(36,37)32-18-22-6-5-21(17-30-13-11-28-12-14-30)16-25(22)31(20(2)33)19-26(32)27(34)29-35/h5-10,16,26,28,35H,11-15,17-19H2,1-2H3,(H,29,34) AXHCVGDTGFVLIU-UHFFFAOYSA-N 50150259 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-piperazin-1-ylmethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL359969 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150259&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393279 104038750 CHEMBL359969 ZINC28375261 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275857 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2cc(ccc2N(CC1C(=O)NO)C(C)=O)N(C)CCc1ccccn1 InChI=1S/C30H33N5O6S/c1-4-5-18-41-26-10-12-27(13-11-26)42(39,40)35-20-23-19-25(33(3)17-15-24-8-6-7-16-31-24)9-14-28(23)34(22(2)36)21-29(35)30(37)32-38/h6-14,16,19,29,38H,15,17-18,20-21H2,1-3H3,(H,32,37) GYDCBTACTORGNU-UHFFFAOYSA-N 50150245 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-[methyl-(2-pyridin-2-yl-ethyl)-amino]-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL363938 Disintegrin and metalloproteinase domain-containing protein 17 121 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150245&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393218 104038736 CHEMBL363938 ZINC34802363 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50275863 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccccc2N(CC1C(=O)NO)C(C)=O InChI=1S/C22H23N3O6S/c1-3-4-13-31-18-9-11-19(12-10-18)32(29,30)25-14-17-7-5-6-8-20(17)24(16(2)26)15-21(25)22(27)23-28/h5-12,21,28H,13-15H2,1-2H3,(H,23,27) PRQWPDFKJBVNKQ-UHFFFAOYSA-N 50118972 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isopropenyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL97790 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/j.bmcl.2004.06.031 10.7270/Q2CV4H62 15261259 Levin, JI; Nelson, FC; Delos Santos, E; Du, MT; MacEwan, G; Chen, JM; Ayral-Kaloustian, S; Xu, J; Jin, G; Cummons, T; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50118972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50118972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868713 104012220 CHEMBL97790 ZINC13818612 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50264188 COc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO InChI=1S/C13H18N2O8S/c1-23-7-2-4-8(5-3-7)24(21,22)15-6-9(16)11(17)12(18)10(15)13(19)14-20/h2-5,9-12,16-18,20H,6H2,1H3,(H,14,19)/t9-,10-,11-,12-/m1/s1 SSQXFNKOLMHXPO-DDHJBXDOSA-N 50143731 (2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-methoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL57644 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143731&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11360440 104032891 CHEMBL57644 ZINC13560272 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50264195 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C18H20N2O7S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)28(26,27)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15-,16-,17-/m1/s1 YFXAPTTTXDTWSV-QBPKDAKJSA-N 50143730 (2R,3R,4R,5R)-1-(Biphenyl-4-sulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL60536 Disintegrin and metalloproteinase domain-containing protein 17 21 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143730&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11407165 104032890 CHEMBL60536 ZINC13560273 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50264198 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@@H](O)[C@@H](O)[C@H](O)[C@@H]1C(=O)NO InChI=1S/C16H20N2O8S/c1-2-3-8-26-10-4-6-11(7-5-10)27(24,25)18-9-12(19)14(20)15(21)13(18)16(22)17-23/h4-7,12-15,19-21,23H,8-9H2,1H3,(H,17,22)/t12-,13-,14-,15-/m1/s1 WSWMIGCNSWBCNT-KBUPBQIOSA-N 50141577 (2R,3R,4R,5R)-1-(4-But-2-ynyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL43087 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50141577 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50141577&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11246575 104031036 CHEMBL43087 ZINC13560275 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50264201 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H22N2O8S/c22-15-10-21(16(19(25)20-26)18(24)17(15)23)30(27,28)14-8-6-13(7-9-14)29-11-12-4-2-1-3-5-12/h1-9,15-18,22-24,26H,10-11H2,(H,20,25)/t15-,16-,17-,18-/m1/s1 LQZDEWIIFWHTLX-BRSBDYLESA-N 50143732 (2R,3R,4R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL58577 Disintegrin and metalloproteinase domain-containing protein 17 1.7 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143732&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11374008 104032892 CHEMBL58577 ZINC13560274 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50264207 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C18H20N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15+,16+,17+/m0/s1 WLWNRAWQDZRXMB-YLFCFFPRSA-N 50131385 (2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::(2R,3R,4R,5S)-N,3,4,5-tetrahydroxy-1-(4-phenoxyphenylsulfonyl)piperidine-2-carboxamide::CHEMBL61193 Disintegrin and metalloproteinase domain-containing protein 17 2.3 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131385&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910222 104022557 CHEMBL61193 6514 ZINC13537266 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50264210 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@H](O)CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C18H20N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15-,16-,17-/m1/s1 WLWNRAWQDZRXMB-QBPKDAKJSA-N 50143729 (2R,3R,4R,5R)-3,4,5-Trihydroxy-1-(4-phenoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::CHEMBL56837 Disintegrin and metalloproteinase domain-containing protein 17 6.2 ChEMBL 10.1021/jm0304313 10.7270/Q2ZS2VXF 15055993 Moriyama, H; Tsukida, T; Inoue, Y; Yokota, K; Yoshino, K; Kondo, H; Miura, N; Nishimura, S Hokkaido Collaboration Center N-21 http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50143729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50143729&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9802436 104032889 CHEMBL56837 ZINC03941984 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268845 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC(=O)CC2)N(O)C=O)c2ccccc2n1 InChI=1S/C26H28N2O6S/c1-18-14-20(24-4-2-3-5-25(24)27-18)15-34-22-10-12-23(13-11-22)35(32,33)16-26(28(31)17-29)19-6-8-21(30)9-7-19/h2-5,10-14,17,19,26,31H,6-9,15-16H2,1H3 QBIHWFSRXVWUDN-UHFFFAOYSA-N 50146469 CHEMBL319782::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexyl)-ethyl]-formamide Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146469 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146469&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23018008 104035058 CHEMBL319782 ZINC26732404 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268848 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCC(=O)CC2)N(O)C=O)c2ccccc2n1 InChI=1S/C27H30N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-14,18,20,22,32H,6-9,15-17H2,1H3 YFYQFPIGOKJLFD-UHFFFAOYSA-N 50146467 CHEMBL99365::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexylmethyl)-ethyl]-formamide Disintegrin and metalloproteinase domain-containing protein 17 4.5 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146467 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146467&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330149 104035056 CHEMBL99365 ZINC05494219 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268867 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCC(=O)CC2)N(O)C=O)c2ccccc2n1 InChI=1S/C27H28N2O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-35-24-10-12-25(13-11-24)36(33,34)17-22(29(32)18-30)15-20-6-8-23(31)9-7-20/h2-5,10-15,18,22,32H,6-9,16-17H2,1H3 VDOSRWCTGZRCFD-UHFFFAOYSA-N 50146468 CHEMBL98852::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(4-oxo-cyclohexylidenemethyl)-ethyl]-formamide Disintegrin and metalloproteinase domain-containing protein 17 3.5 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146468&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330163 104035057 CHEMBL98852 ZINC26740925 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268869 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1 InChI=1S/C27H29N3O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-36-24-10-12-25(13-11-24)37(34,35)17-23(30(33)18-31)15-20-6-8-22(29-32)9-7-20/h2-5,10-15,18,22-23,33H,6-9,16-17H2,1H3/b20-15- WRJBRPUQVWCVQK-HKWRFOASSA-N 50146476 CHEMBL99995::N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146476&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 90925631 104035065 CHEMBL99995 ZINC26736036 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268870 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC3(CC2)OCCO3)N(O)C=O)c2ccccc2n1 InChI=1S/C28H32N2O7S/c1-20-16-22(25-4-2-3-5-26(25)29-20)17-35-23-6-8-24(9-7-23)38(33,34)18-27(30(32)19-31)21-10-12-28(13-11-21)36-14-15-37-28/h2-9,16,19,21,27,32H,10-15,17-18H2,1H3 IDKUTWZTCGVYET-UHFFFAOYSA-N 50146471 CHEMBL431226::N-{1-(1,4-Dioxa-spiro[4.5]dec-8-yl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-N-hydroxy-formamide Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146471&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330135 104035060 CHEMBL431226 ZINC26739357 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268876 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1 InChI=1S/C27H31N3O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-36-24-10-12-25(13-11-24)37(34,35)17-23(30(33)18-31)15-20-6-8-22(29-32)9-7-20/h2-5,10-14,18,20,22-23,33H,6-9,15-17H2,1H3 AXBBWELSCMNUPM-UHFFFAOYSA-N 50146480 CHEMBL329967::N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylmethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146480&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91932927 104035069 CHEMBL329967 ZINC26740915 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268881 CC(C)CN1CCC(CC1)=CC(CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)N(O)C=O InChI=1S/C30H37N3O5S/c1-22(2)18-32-14-12-24(13-15-32)17-26(33(35)21-34)20-39(36,37)28-10-8-27(9-11-28)38-19-25-16-23(3)31-30-7-5-4-6-29(25)30/h4-11,16-17,21-22,26,35H,12-15,18-20H2,1-3H3 ODPDWLUYVWCNHO-UHFFFAOYSA-N 50146472 CHEMBL318252::N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide::N-hydroxy-N-(1-(1-isobutylpiperidin-4-ylidene)-3-(4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)propan-2-yl)formamide Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330147 104035061 CHEMBL318252 ZINC14175331 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268886 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1 InChI=1S/C26H29N3O6S/c1-18-14-20(24-4-2-3-5-25(24)27-18)15-35-22-10-12-23(13-11-22)36(33,34)16-26(29(32)17-30)19-6-8-21(28-31)9-7-19/h2-5,10-14,17,19,21,26,32H,6-9,15-16H2,1H3 MKUAQMILBQCRIR-UHFFFAOYSA-N 50146479 CHEMBL328645::N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146479&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91932926 104035068 CHEMBL328645 ZINC26736728 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268887 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCN(CC2)OC(=O)C(C)(C)C)N(O)C=O)c2ccccc2n1 InChI=1S/C31H37N3O7S/c1-22-17-24(28-7-5-6-8-29(28)32-22)19-40-26-9-11-27(12-10-26)42(38,39)20-25(34(37)21-35)18-23-13-15-33(16-14-23)41-30(36)31(2,3)4/h5-12,17-18,21,25,37H,13-16,19-20H2,1-4H3 FUYGKZYSHSZHFI-UHFFFAOYSA-N 50146473 2,2-Dimethyl-propionic acid 4-{2-(formyl-hydroxy-amino)-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-propylidene}-piperidin-1-yl ester::CHEMBL95414 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146473&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329898 104035062 CHEMBL95414 ZINC34801761 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268890 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCC3(CC2)OCCO3)N(O)C=O)c2ccccc2n1 InChI=1S/C29H34N2O7S/c1-21-16-23(27-4-2-3-5-28(27)30-21)18-36-25-6-8-26(9-7-25)39(34,35)19-24(31(33)20-32)17-22-10-12-29(13-11-22)37-14-15-38-29/h2-9,16,20,22,24,33H,10-15,17-19H2,1H3 KBRVEWFSDCONMH-UHFFFAOYSA-N 50146474 CHEMBL419896::N-{2-(1,4-Dioxa-spiro[4.5]dec-8-yl)-1-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-ethyl}-N-hydroxy-formamide Disintegrin and metalloproteinase domain-containing protein 17 60 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146474&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330152 104035063 CHEMBL419896 ZINC26732359 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268903 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C2CCC(=C)CC2)N(O)C=O)c2ccccc2n1 InChI=1S/C27H30N2O5S/c1-19-7-9-21(10-8-19)27(29(31)18-30)17-35(32,33)24-13-11-23(12-14-24)34-16-22-15-20(2)28-26-6-4-3-5-25(22)26/h3-6,11-15,18,21,27,31H,1,7-10,16-17H2,2H3 GZISYEQJJGPWOA-UHFFFAOYSA-N 50146470 CHEMBL328199::N-Hydroxy-N-{1-(4-methylene-cyclohexyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide Disintegrin and metalloproteinase domain-containing protein 17 45 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146470&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10141443 104035059 CHEMBL328199 ZINC26743233 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268909 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCSCC2)N(O)C=O)c2ccccc2n1 InChI=1S/C26H28N2O5S2/c1-19-14-21(25-4-2-3-5-26(25)27-19)16-33-23-6-8-24(9-7-23)35(31,32)17-22(28(30)18-29)15-20-10-12-34-13-11-20/h2-9,14-15,18,22,30H,10-13,16-17H2,1H3 KQXZHGMAVQYCLA-UHFFFAOYSA-N 50146475 CHEMBL98202::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-thiopyran-4-ylidenemethyl)-ethyl]-formamide Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146475&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330132 104035064 CHEMBL98202 ZINC26735959 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268914 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCOCC2)N(O)C=O)c2ccccc2n1 InChI=1S/C26H28N2O6S/c1-19-14-21(25-4-2-3-5-26(25)27-19)16-34-23-6-8-24(9-7-23)35(31,32)17-22(28(30)18-29)15-20-10-12-33-13-11-20/h2-9,14-15,18,22,30H,10-13,16-17H2,1H3 QSRYPQMSBYPAQC-UHFFFAOYSA-N 50146477 CHEMBL99045::N-Hydroxy-N-[2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-1-(tetrahydro-pyran-4-ylidenemethyl)-ethyl]-formamide Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146477&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23017979 104035066 CHEMBL99045 ZINC13974363 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50268915 CC(C)CN1CCC(CC(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)N(O)C=O)CC1 InChI=1S/C30H39N3O5S/c1-22(2)18-32-14-12-24(13-15-32)17-26(33(35)21-34)20-39(36,37)28-10-8-27(9-11-28)38-19-25-16-23(3)31-30-7-5-4-6-29(25)30/h4-11,16,21-22,24,26,35H,12-15,17-20H2,1-3H3 AYWKRESAZCSENH-UHFFFAOYSA-N 50146478 CHEMBL98390::N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylmethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2004.03.048 10.7270/Q27S7N7C 15125955 Kamei, N; Tanaka, T; Kawai, K; Miyawaki, K; Okuyama, A; Murakami, Y; Arakawa, Y; Haino, M; Harada, T; Shimano, M Kaken Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146478&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10437629 104035067 CHEMBL98390 ZINC26737093 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281169 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCCN2)c2ccccc2n1 InChI=1S/C25H29N3O5S/c1-18-14-19(22-6-2-3-7-23(22)27-18)16-33-20-8-10-21(11-9-20)34(31,32)17-25(15-24(29)28-30)12-4-5-13-26-25/h2-3,6-11,14,26,30H,4-5,12-13,15-17H2,1H3,(H,28,29) MBVFAXQWLSRZPW-UHFFFAOYSA-N 50152915 CHEMBL185321::N-Hydroxy-2-{2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-2-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 632 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152915&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10299665 104040922 CHEMBL185321 ZINC28376204 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281177 CCCCN1CCC(C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1)C(=O)NO InChI=1S/C28H35N3O5S/c1-3-4-14-31-15-13-26(28(32)30-33)22(17-31)19-37(34,35)24-11-9-23(10-12-24)36-18-21-16-20(2)29-27-8-6-5-7-25(21)27/h5-12,16,22,26,33H,3-4,13-15,17-19H2,1-2H3,(H,30,32) IGCXXFVEWDCCKV-UHFFFAOYSA-N 50152910 1-Butyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL363451 Disintegrin and metalloproteinase domain-containing protein 17 900 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152910 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152910&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002775 104040917 CHEMBL363451 ZINC36351970 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281186 CN1CCCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 InChI=1S/C26H31N3O5S/c1-19-14-20(23-6-3-4-7-24(23)27-19)16-34-21-8-10-22(11-9-21)35(32,33)18-26(15-25(30)28-31)12-5-13-29(2)17-26/h3-4,6-11,14,31H,5,12-13,15-18H2,1-2H3,(H,28,30) NGBXKQSVMZPDNE-UHFFFAOYSA-N 50152899 CHEMBL365031::N-Hydroxy-2-{1-methyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 208 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152899 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152899&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10117663 104040906 CHEMBL365031 ZINC28372163 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281188 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CNCCC2C(=O)NO)c2ccccc2n1 InChI=1S/C24H27N3O5S/c1-16-12-17(21-4-2-3-5-23(21)26-16)14-32-19-6-8-20(9-7-19)33(30,31)15-18-13-25-11-10-22(18)24(28)27-29/h2-9,12,18,22,25,29H,10-11,13-15H2,1H3,(H,27,28) YCBSBKZAEBKTSY-UHFFFAOYSA-N 50152920 3-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL426434 Disintegrin and metalloproteinase domain-containing protein 17 250 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152920 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152920&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002771 104040927 CHEMBL426434 ZINC28374334 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281195 CN1CCC(C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1)C(=O)NO InChI=1S/C25H29N3O5S/c1-17-13-18(22-5-3-4-6-24(22)26-17)15-33-20-7-9-21(10-8-20)34(31,32)16-19-14-28(2)12-11-23(19)25(29)27-30/h3-10,13,19,23,30H,11-12,14-16H2,1-2H3,(H,27,29) ZLXSMXRIMOZSHG-UHFFFAOYSA-N 50152927 1-Methyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL184265 Disintegrin and metalloproteinase domain-containing protein 17 190 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152927&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002715 104040934 CHEMBL184265 ZINC03818003 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281196 CC(C)N1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 InChI=1S/C27H33N3O5S/c1-19(2)30-13-12-27(17-30,15-26(31)29-32)18-36(33,34)23-10-8-22(9-11-23)35-16-21-14-20(3)28-25-7-5-4-6-24(21)25/h4-11,14,19,32H,12-13,15-18H2,1-3H3,(H,29,31) AENHIDVKFOYIJJ-UHFFFAOYSA-N 50152924 CHEMBL184553::N-Hydroxy-2-{1-isopropyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 77 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152924 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152924&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10207780 104040931 CHEMBL184553 ZINC28378033 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281207 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCC2)c2ccccc2n1 InChI=1S/C25H28N2O5S/c1-18-14-19(22-6-2-3-7-23(22)26-18)16-32-20-8-10-21(11-9-20)33(30,31)17-25(12-4-5-13-25)15-24(28)27-29/h2-3,6-11,14,29H,4-5,12-13,15-17H2,1H3,(H,27,28) KVMYRTIGLLQRFY-UHFFFAOYSA-N 50152922 CHEMBL184302::N-Hydroxy-2-{1-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-cyclopentyl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 420 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152922 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152922&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10276821 104040929 CHEMBL184302 ZINC28376888 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281209 CC(C)N1CCC(C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1)C(=O)NO InChI=1S/C27H33N3O5S/c1-18(2)30-13-12-25(27(31)29-32)21(15-30)17-36(33,34)23-10-8-22(9-11-23)35-16-20-14-19(3)28-26-7-5-4-6-24(20)26/h4-11,14,18,21,25,32H,12-13,15-17H2,1-3H3,(H,29,31) RLQDDFZTFKMONF-UHFFFAOYSA-N 50152900 1-Isopropyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL181807 Disintegrin and metalloproteinase domain-containing protein 17 230 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152900 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152900&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002726 104040907 CHEMBL181807 ZINC28358261 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281227 CN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)CC1 InChI=1S/C26H31N3O5S/c1-19-15-20(23-5-3-4-6-24(23)27-19)17-34-21-7-9-22(10-8-21)35(32,33)18-26(16-25(30)28-31)11-13-29(2)14-12-26/h3-10,15,31H,11-14,16-18H2,1-2H3,(H,28,30) GQEXSMDDEGSZJA-UHFFFAOYSA-N 50152931 CHEMBL185587::N-Hydroxy-2-{1-methyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-4-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 102 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152931 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152931&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10141614 104040938 CHEMBL185587 ZINC28374759 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281234 CC(C)CN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 InChI=1S/C28H35N3O5S/c1-20(2)16-31-13-12-28(18-31,15-27(32)30-33)19-37(34,35)24-10-8-23(9-11-24)36-17-22-14-21(3)29-26-7-5-4-6-25(22)26/h4-11,14,20,33H,12-13,15-19H2,1-3H3,(H,30,32) QNVRWDPZVVAENF-UHFFFAOYSA-N 50152930 CHEMBL359569::N-Hydroxy-2-{1-isobutyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 161 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152930 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152930&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10165180 104040937 CHEMBL359569 ZINC28373067 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281237 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCCC2)c2ccccc2n1 InChI=1S/C26H30N2O5S/c1-19-15-20(23-7-3-4-8-24(23)27-19)17-33-21-9-11-22(12-10-21)34(31,32)18-26(16-25(29)28-30)13-5-2-6-14-26/h3-4,7-12,15,30H,2,5-6,13-14,16-18H2,1H3,(H,28,29) UXWAVVXCMUJGHD-UHFFFAOYSA-N 50152928 CHEMBL365905::N-Hydroxy-2-{1-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-cyclohexyl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 867 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152928 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152928&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10140776 104040935 CHEMBL365905 ZINC28372137 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281247 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCNC2)c2ccccc2n1 InChI=1S/C24H27N3O5S/c1-17-12-18(21-4-2-3-5-22(21)26-17)14-32-19-6-8-20(9-7-19)33(30,31)16-24(10-11-25-15-24)13-23(28)27-29/h2-9,12,25,29H,10-11,13-16H2,1H3,(H,27,28) QKSLJJWUWAALHK-UHFFFAOYSA-N 50152905 CHEMBL184782::N-Hydroxy-2-{3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 76 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152905 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152905&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10162245 104040912 CHEMBL184782 ZINC28373817 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281251 CN1CCC(C1CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C24H27N3O5S/c1-16-13-17(20-5-3-4-6-22(20)25-16)14-32-18-7-9-19(10-8-18)33(30,31)15-23-21(24(28)26-29)11-12-27(23)2/h3-10,13,21,23,29H,11-12,14-15H2,1-2H3,(H,26,28) QPQUYVHWOXJEPM-UHFFFAOYSA-N 50152901 1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidine-3-carboxylic acid hydroxyamide::CHEMBL184885::N-hydroxy-1-methyl-2-((4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)methyl)pyrrolidine-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 180 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152901&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002758 104040908 CHEMBL184885 ZINC36151532 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281257 CONC(=O)[C@H]1CCCN(C)[C@@H]1C(=O)Nc1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H30N4O4/c1-17-15-18(21-7-4-5-9-23(21)27-17)16-34-20-12-10-19(11-13-20)28-26(32)24-22(25(31)29-33-3)8-6-14-30(24)2/h4-5,7,9-13,15,22,24H,6,8,14,16H2,1-3H3,(H,28,32)(H,29,31)/t22-,24-/m0/s1 ZJOWVJCIVPTYBC-UPVQGACJSA-N 50152916 (S)-1-Methyl-piperidine-2,3-dicarboxylic acid 3-(methoxy-amide) 2-{[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-amide}::CHEMBL183791 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152916 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152916&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44394179 104040923 CHEMBL183791 ZINC28382272 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281263 CCC(C)N1CCC(C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1)C(=O)NO InChI=1S/C28H35N3O5S/c1-4-20(3)31-14-13-26(28(32)30-33)22(16-31)18-37(34,35)24-11-9-23(10-12-24)36-17-21-15-19(2)29-27-8-6-5-7-25(21)27/h5-12,15,20,22,26,33H,4,13-14,16-18H2,1-3H3,(H,30,32) XDBJJTDYSZNDQT-UHFFFAOYSA-N 50152912 1-sec-Butyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL184942 Disintegrin and metalloproteinase domain-containing protein 17 1070 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152912 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152912&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393520 104040919 CHEMBL184942 ZINC36351972 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281274 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCNC2)c2ccccc2n1 InChI=1S/C25H29N3O5S/c1-18-13-19(22-5-2-3-6-23(22)27-18)15-33-20-7-9-21(10-8-20)34(31,32)17-25(14-24(29)28-30)11-4-12-26-16-25/h2-3,5-10,13,26,30H,4,11-12,14-17H2,1H3,(H,28,29) ZYBZWGUZKUJPEX-UHFFFAOYSA-N 50152904 CHEMBL184975::N-Hydroxy-2-{3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 123 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152904 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152904&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10227853 104040911 CHEMBL184975 ZINC28373053 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281283 CCCCCN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 InChI=1S/C29H37N3O5S/c1-3-4-7-15-32-16-14-29(20-32,18-28(33)31-34)21-38(35,36)25-12-10-24(11-13-25)37-19-23-17-22(2)30-27-9-6-5-8-26(23)27/h5-6,8-13,17,34H,3-4,7,14-16,18-21H2,1-2H3,(H,31,33) YDTKUAMJIYPIGB-UHFFFAOYSA-N 50152936 CHEMBL363732::N-Hydroxy-2-{3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-1-pentyl-pyrrolidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 418 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152936 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152936&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393444 104040943 CHEMBL363732 ZINC28372177 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281285 CN1CCCC1(CC(=O)NO)CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C25H29N3O5S/c1-18-14-19(22-6-3-4-7-23(22)26-18)16-33-20-8-10-21(11-9-20)34(31,32)17-25(15-24(29)27-30)12-5-13-28(25)2/h3-4,6-11,14,30H,5,12-13,15-17H2,1-2H3,(H,27,29) VMEQJHZAHNCRQC-UHFFFAOYSA-N 50152913 CHEMBL182730::N-Hydroxy-2-{1-methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidin-2-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152913&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10277706 104040920 CHEMBL182730 ZINC28355782 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281299 CC(C)CN1CCCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 InChI=1S/C29H37N3O5S/c1-21(2)17-32-14-6-13-29(19-32,16-28(33)31-34)20-38(35,36)25-11-9-24(10-12-25)37-18-23-15-22(3)30-27-8-5-4-7-26(23)27/h4-5,7-12,15,21,34H,6,13-14,16-20H2,1-3H3,(H,31,33) GZPFSVVEOIXUBD-UHFFFAOYSA-N 50152923 CHEMBL183828::N-Hydroxy-2-{1-isobutyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 2503 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152923 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152923&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10143587 104040930 CHEMBL183828 ZINC28351237 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281300 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CN(CC=C)CCC2C(=O)NO)c2ccccc2n1 InChI=1S/C27H31N3O5S/c1-3-13-30-14-12-25(27(31)29-32)21(16-30)18-36(33,34)23-10-8-22(9-11-23)35-17-20-15-19(2)28-26-7-5-4-6-24(20)26/h3-11,15,21,25,32H,1,12-14,16-18H2,2H3,(H,29,31) PGTJOSSSBWAALE-UHFFFAOYSA-N 50152909 1-Allyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL185159 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152909 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152909&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002722 104040916 CHEMBL185159 ZINC28371847 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281317 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CN(CCC2C(=O)NO)C#C)c2ccccc2n1 InChI=1S/C26H27N3O5S/c1-3-29-13-12-24(26(30)28-31)20(15-29)17-35(32,33)22-10-8-21(9-11-22)34-16-19-14-18(2)27-25-7-5-4-6-23(19)25/h1,4-11,14,20,24,31H,12-13,15-17H2,2H3,(H,28,30) VACPECYZKUSTIV-UHFFFAOYSA-N 50152914 1-Ethynyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL363968 Disintegrin and metalloproteinase domain-containing protein 17 180 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152914&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44393516 104040921 CHEMBL363968 ZINC28377993 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281320 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)COC2)c2ccccc2n1 InChI=1S/C23H24N2O6S/c1-16-10-17(20-4-2-3-5-21(20)24-16)12-31-18-6-8-19(9-7-18)32(28,29)15-23(13-30-14-23)11-22(26)25-27/h2-10,27H,11-15H2,1H3,(H,25,26) JTEXDSSTTHRJGK-UHFFFAOYSA-N 50152917 CHEMBL361376::N-Hydroxy-2-{3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-oxetan-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 595 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10204620 104040924 CHEMBL361376 ZINC28351242 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281324 CN1CCCC(C1CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H29N3O5S/c1-17-14-18(21-6-3-4-8-23(21)26-17)15-33-19-9-11-20(12-10-19)34(31,32)16-24-22(25(29)27-30)7-5-13-28(24)2/h3-4,6,8-12,14,22,24,30H,5,7,13,15-16H2,1-2H3,(H,27,29) HTTGXWWZNURROV-UHFFFAOYSA-N 50152911 1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-3-carboxylic acid hydroxyamide::CHEMBL362100 Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152911 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152911&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002752 104040918 CHEMBL362100 ZINC36351973 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281328 CC(C)N1CCC(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(C1)C(=O)NO InChI=1S/C27H33N3O5S/c1-18(2)30-13-12-20(25(15-30)27(31)29-32)17-36(33,34)23-10-8-22(9-11-23)35-16-21-14-19(3)28-26-7-5-4-6-24(21)26/h4-11,14,18,20,25,32H,12-13,15-17H2,1-3H3,(H,29,31) IFZNBBFLMYGGPO-UHFFFAOYSA-N 50152937 1-Isopropyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-3-carboxylic acid hydroxyamide::CHEMBL185521 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152937 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152937&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002765 104040944 CHEMBL185521 ZINC28375438 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281332 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCOCC2)c2ccccc2n1 InChI=1S/C25H28N2O6S/c1-18-14-19(22-4-2-3-5-23(22)26-18)16-33-20-6-8-21(9-7-20)34(30,31)17-25(15-24(28)27-29)10-12-32-13-11-25/h2-9,14,29H,10-13,15-17H2,1H3,(H,27,28) KCWUMRBDUUZPAL-UHFFFAOYSA-N 50152902 CHEMBL185397::N-Hydroxy-2-{4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-tetrahydro-pyran-4-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 258 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152902 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152902&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10184579 104040909 CHEMBL185397 ZINC28372217 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281335 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2NCCCC2C(=O)NO)c2ccccc2n1 InChI=1S/C24H27N3O5S/c1-16-13-17(20-5-2-3-7-22(20)26-16)14-32-18-8-10-19(11-9-18)33(30,31)15-23-21(24(28)27-29)6-4-12-25-23/h2-3,5,7-11,13,21,23,25,29H,4,6,12,14-15H2,1H3,(H,27,28) QDMJDGKLXWJUSU-UHFFFAOYSA-N 50152907 2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-3-carboxylic acid hydroxyamide::CHEMBL184062 Disintegrin and metalloproteinase domain-containing protein 17 240 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152907 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152907&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002729 104040914 CHEMBL184062 ZINC28382645 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281338 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCO2)c2ccccc2n1 InChI=1S/C24H26N2O6S/c1-17-13-18(21-5-2-3-6-22(21)25-17)15-31-19-7-9-20(10-8-19)33(29,30)16-24(11-4-12-32-24)14-23(27)26-28/h2-3,5-10,13,28H,4,11-12,14-16H2,1H3,(H,26,27) LCIIHDPWZSSNGB-UHFFFAOYSA-N 50152932 CHEMBL183868::N-Hydroxy-2-{2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-tetrahydro-furan-2-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 913.0 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152932 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152932&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10183693 104040939 CHEMBL183868 ZINC28355747 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281340 CC(C)N1CCCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 InChI=1S/C28H35N3O5S/c1-20(2)31-14-6-13-28(18-31,16-27(32)30-33)19-37(34,35)24-11-9-23(10-12-24)36-17-22-15-21(3)29-26-8-5-4-7-25(22)26/h4-5,7-12,15,20,33H,6,13-14,16-19H2,1-3H3,(H,30,32) SUTQJRNQIINAFC-UHFFFAOYSA-N 50152918 CHEMBL184266::N-Hydroxy-2-{1-isopropyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 506.0 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152918 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152918&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10186544 104040925 CHEMBL184266 ZINC28380887 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281342 CN1CCC(CC(=O)NO)(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 InChI=1S/C25H29N3O5S/c1-18-13-19(22-5-3-4-6-23(22)26-18)15-33-20-7-9-21(10-8-20)34(31,32)17-25(14-24(29)27-30)11-12-28(2)16-25/h3-10,13,30H,11-12,14-17H2,1-2H3,(H,27,29) HUNBFLZYPNPINY-UHFFFAOYSA-N 50152929 CHEMBL434348::N-Hydroxy-2-{1-methyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidin-3-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 109 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152929 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152929&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10184537 104040936 CHEMBL434348 ZINC28378528 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281344 CN1CCC(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C(C1)C(=O)NO InChI=1S/C25H29N3O5S/c1-17-13-19(22-5-3-4-6-24(22)26-17)15-33-20-7-9-21(10-8-20)34(31,32)16-18-11-12-28(2)14-23(18)25(29)27-30/h3-10,13,18,23,30H,11-12,14-16H2,1-2H3,(H,27,29) UJCQVXJYOKSWGB-UHFFFAOYSA-N 50152908 1-Methyl-4-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-3-carboxylic acid hydroxyamide::CHEMBL359625 Disintegrin and metalloproteinase domain-containing protein 17 510 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152908 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152908&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002745 104040915 CHEMBL359625 ZINC28355762 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281345 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2NCCC2C(=O)NO)c2ccccc2n1 InChI=1S/C23H25N3O5S/c1-15-12-16(19-4-2-3-5-21(19)25-15)13-31-17-6-8-18(9-7-17)32(29,30)14-22-20(10-11-24-22)23(27)26-28/h2-9,12,20,22,24,28H,10-11,13-14H2,1H3,(H,26,27) NWEMVUGYMZFTLT-UHFFFAOYSA-N 50152926 2-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidine-3-carboxylic acid hydroxyamide::CHEMBL185279 Disintegrin and metalloproteinase domain-containing protein 17 83 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152926 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152926&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002736 104040933 CHEMBL185279 ZINC28371617 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281347 CN1CCCCC1(CC(=O)NO)CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H31N3O5S/c1-19-15-20(23-7-3-4-8-24(23)27-19)17-34-21-9-11-22(12-10-21)35(32,33)18-26(16-25(30)28-31)13-5-6-14-29(26)2/h3-4,7-12,15,31H,5-6,13-14,16-18H2,1-2H3,(H,28,30) OOVNTYFKKPGWIY-UHFFFAOYSA-N 50152919 CHEMBL184200::N-Hydroxy-2-{1-methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidin-2-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152919 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152919&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10141613 104040926 CHEMBL184200 ZINC28380102 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281362 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCC2)c2ccccc2n1 InChI=1S/C24H26N2O5S/c1-17-13-18(21-5-2-3-6-22(21)25-17)15-31-19-7-9-20(10-8-19)32(29,30)16-24(11-4-12-24)14-23(27)26-28/h2-3,5-10,13,28H,4,11-12,14-16H2,1H3,(H,26,27) MCBALNMZVCCHAP-UHFFFAOYSA-N 50152933 CHEMBL364875::N-Hydroxy-2-{1-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-cyclobutyl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 223 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152933 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152933&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10226116 104040940 CHEMBL364875 ZINC28382618 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281369 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2(CC(=O)NO)CCCN2)c2ccccc2n1 InChI=1S/C24H27N3O5S/c1-17-13-18(21-5-2-3-6-22(21)26-17)15-32-19-7-9-20(10-8-19)33(30,31)16-24(11-4-12-25-24)14-23(28)27-29/h2-3,5-10,13,25,29H,4,11-12,14-16H2,1H3,(H,27,28) TUZYRFJHUHCUNQ-UHFFFAOYSA-N 50152906 CHEMBL364589::N-Hydroxy-2-{2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidin-2-yl}-acetamide Disintegrin and metalloproteinase domain-containing protein 17 403.0 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152906 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152906&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9825920 104040913 CHEMBL364589 ZINC28368062 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50281372 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC2CCNCC2C(=O)NO)c2ccccc2n1 InChI=1S/C24H27N3O5S/c1-16-12-18(21-4-2-3-5-23(21)26-16)14-32-19-6-8-20(9-7-19)33(30,31)15-17-10-11-25-13-22(17)24(28)27-29/h2-9,12,17,22,25,29H,10-11,13-15H2,1H3,(H,27,28) VTKKCTKODCNOOX-UHFFFAOYSA-N 50152934 4-[4-(2-Methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-piperidine-3-carboxylic acid hydroxyamide::CHEMBL183431 Disintegrin and metalloproteinase domain-containing protein 17 250 ChEMBL 10.1016/j.bmcl.2004.06.049 10.7270/Q2NV9HRM 15357971 Xue, CB; Chen, XT; He, X; Roderick, J; Corbett, RL; Ghavimi, B; Liu, RQ; Covington, MB; Qian, M; Ribadeneira, MD; Vaddi, K; Trzaskos, J; Newton, RC; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152934 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152934&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002764 104040941 CHEMBL183431 ZINC28354562 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287955 ONC(=O)C1(CCN(Cc2ccccc2)CC1)S(=O)(=O)c1ccc(OCC#C)cc1 InChI=1S/C22H24N2O5S/c1-2-16-29-19-8-10-20(11-9-19)30(27,28)22(21(25)23-26)12-14-24(15-13-22)17-18-6-4-3-5-7-18/h1,3-11,26H,12-17H2,(H,23,25) XAUUSUAZNMIGRK-UHFFFAOYSA-N 50156695 1-benzyl-N-hydroxy-4-(4-(prop-2-ynyloxy)phenylsulfonyl)piperidine-4-carboxamide::CHEMBL373831 Disintegrin and metalloproteinase domain-containing protein 17 69 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156695&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11258906 104043804 CHEMBL373831 ZINC13586045 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287959 CC#CCOc1ccc(cc1)[S@@+]([O-])[C@@H](C(C)C)C(=O)NO InChI=1S/C15H19NO4S/c1-4-5-10-20-12-6-8-13(9-7-12)21(19)14(11(2)3)15(17)16-18/h6-9,11,14,18H,10H2,1-3H3,(H,16,17) YYOVZJXOBZVIQK-UHFFFAOYSA-N 50156697 (S)-2-[(S)-4-but-2-ynyloxyphenylsulfinyl)-2-isopropyl-N-hydroxyacetamide::CHEMBL3085322 Disintegrin and metalloproteinase domain-containing protein 17 6480 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156697&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 76331563 104043806 CHEMBL3085322 ZINC13585956 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287962 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO InChI=1S/C23H25BrN2O5S/c1-2-3-16-31-20-8-10-21(11-9-20)32(29,30)23(22(27)25-28)12-14-26(15-13-23)17-18-4-6-19(24)7-5-18/h4-11,28H,12-17H2,1H3,(H,25,27) MNQFMKHWJNOSIX-UHFFFAOYSA-N 50156701 1-(4-bromobenzyl)-4-(4-but-2-ynyxoybenzenesulfonyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL222854 Disintegrin and metalloproteinase domain-containing protein 17 65 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156701&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9849576 104043810 CHEMBL222854 ZINC13586041 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287964 CC#CCOc1ccc(SC(C(C)C)C(=O)NO)cc1 InChI=1S/C15H19NO3S/c1-4-5-10-19-12-6-8-13(9-7-12)20-14(11(2)3)15(17)16-18/h6-9,11,14,18H,10H2,1-3H3,(H,16,17) JUKIJVGLFPZICB-UHFFFAOYSA-N 50156700 2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-isopropyl-N-hydroxyacetamide::CHEMBL222935 Disintegrin and metalloproteinase domain-containing protein 17 157 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156700&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9879183 104043809 CHEMBL222935 ZINC13585948 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287969 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCCCC1)C(=O)NO InChI=1S/C18H23NO5S/c1-2-3-13-24-15-9-11-16(12-10-15)25(22,23)17(18(20)19-21)14-7-5-4-6-8-14/h9-12,14,17,21H,4-8,13H2,1H3,(H,19,20) MKEVHBFZBURDHJ-UHFFFAOYSA-N 50156705 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-2-cyclohexyl-N-hydroxyacetamide::CHEMBL222282 Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156705&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9947270 104043814 CHEMBL222282 ZINC13586005 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287972 CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C18H24N2O5S/c1-3-5-14-25-15-6-8-16(9-7-15)26(23,24)18(17(21)19-22)10-12-20(4-2)13-11-18/h6-9,22H,4,10-14H2,1-2H3,(H,19,21) URNZIKDWYXXADG-UHFFFAOYSA-N 50156709 4-(4-But-2-ynyloxy-benzenesulfonyl)-1-ethyl-piperidine-4-carboxylic acid hydroxyamide::4-(4-but-2-ynyloxybenzenesulfonyl)-1-ethylpiperdine-4-carboxylic acid hydroxyamide::CHEMBL197877 Disintegrin and metalloproteinase domain-containing protein 17 80 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156709 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156709&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11247057 104043818 CHEMBL197877 ZINC13586056 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287976 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCNCC1)C(=O)NO InChI=1S/C17H22N2O5S/c1-2-3-12-24-14-4-6-15(7-5-14)25(22,23)16(17(20)19-21)13-8-10-18-11-9-13/h4-7,13,16,18,21H,8-12H2,1H3,(H,19,20) RLWLGGMXWQFGGX-UHFFFAOYSA-N 50156703 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(4-piperidinyl)acetamide::CHEMBL374953 Disintegrin and metalloproteinase domain-containing protein 17 299 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156703&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10270268 104043812 CHEMBL374953 ZINC13586021 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287977 CC#CCOc1ccc(cc1)S(=O)(=O)C(C(C)C)C(=O)NO InChI=1S/C15H19NO5S/c1-4-5-10-21-12-6-8-13(9-7-12)22(19,20)14(11(2)3)15(17)16-18/h6-9,11,14,18H,10H2,1-3H3,(H,16,17) KTMMYBDZBIJPLY-UHFFFAOYSA-N 50156708 2-[4-(2-butynyloxy)phenyl]sulfonyl}-2-isopropyl-N-hydroxyacetamide::CHEMBL222594 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156708 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156708&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9858468 104043817 CHEMBL222594 ZINC13585960 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287984 CCCCCCC(C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C15H23NO5S/c1-3-4-5-6-7-14(15(17)16-18)22(19,20)13-10-8-12(21-2)9-11-13/h8-11,14,18H,3-7H2,1-2H3,(H,16,17) VMCQYTNLTZJCIG-UHFFFAOYSA-N 50156713 2-(4-methoxybenzenesulfonyl)octanoic acid hydroxyamide::CHEMBL375319 Disintegrin and metalloproteinase domain-containing protein 17 966 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156713&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10042214 104043822 CHEMBL375319 ZINC13585930 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287986 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCN(CC1)C(C)=O)C(=O)NO InChI=1S/C19H24N2O6S/c1-3-4-13-27-16-5-7-17(8-6-16)28(25,26)18(19(23)20-24)15-9-11-21(12-10-15)14(2)22/h5-8,15,18,24H,9-13H2,1-2H3,(H,20,23) MDNQMINKKFNDQI-UHFFFAOYSA-N 50156706 2-(1-acetyl-4-piperidinyl)-2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxyacetamide::CHEMBL374114 Disintegrin and metalloproteinase domain-containing protein 17 119 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156706 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156706&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10158366 104043815 CHEMBL374114 ZINC13586029 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287990 CC#CCOc1ccc(SC(C(=O)NO)c2ccccc2)cc1 InChI=1S/C18H17NO3S/c1-2-3-13-22-15-9-11-16(12-10-15)23-17(18(20)19-21)14-7-5-4-6-8-14/h4-12,17,21H,13H2,1H3,(H,19,20) CDIBBFPULKXHGN-UHFFFAOYSA-N 50156698 2-(4-(but-2-ynyloxy)phenylthio)-N-hydroxy-2-phenylacetamide::CHEMBL373694 Disintegrin and metalloproteinase domain-containing protein 17 50 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156698&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10268288 104043807 CHEMBL373694 ZINC13585964 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287992 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Cl)cc2)CC1)C(=O)NO InChI=1S/C23H25ClN2O5S/c1-2-3-16-31-20-8-10-21(11-9-20)32(29,30)23(22(27)25-28)12-14-26(15-13-23)17-18-4-6-19(24)7-5-18/h4-11,28H,12-17H2,1H3,(H,25,27) MWQQOCVRFAKHSC-UHFFFAOYSA-N 50156717 4-(4-but-2-ynyloxybenzenesulfonyl)-1-(4-chlorobenzyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL224845 Disintegrin and metalloproteinase domain-containing protein 17 55 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156717&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9912879 104043826 CHEMBL224845 ZINC13586050 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288004 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCN(CC1)C(=O)C1CC1)C(=O)NO InChI=1S/C21H26N2O6S/c1-2-3-14-29-17-6-8-18(9-7-17)30(27,28)19(20(24)22-26)15-10-12-23(13-11-15)21(25)16-4-5-16/h6-9,15-16,19,26H,4-5,10-14H2,1H3,(H,22,24) LJPYOTNMYOBJHB-UHFFFAOYSA-N 50156715 2-(4-(but-2-ynyloxy)phenylsulfonyl)-2-(1-(cyclopropanecarbonyl)piperidin-4-yl)-N-hydroxyacetamide::CHEMBL223831 Disintegrin and metalloproteinase domain-containing protein 17 54 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156715&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11201367 104043824 CHEMBL223831 ZINC13586037 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288007 CCCCCC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO InChI=1S/C27H33BrN2O5S/c1-2-3-4-5-6-7-20-35-24-12-14-25(15-13-24)36(33,34)27(26(31)29-32)16-18-30(19-17-27)21-22-8-10-23(28)11-9-22/h8-15,32H,2-5,16-21H2,1H3,(H,29,31) WGANCLOVDGTTMN-UHFFFAOYSA-N 50156723 1-(4-bromobenzyl)-4-(4-oct-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL222397 Disintegrin and metalloproteinase domain-containing protein 17 393 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156723&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9894447 104043832 CHEMBL222397 ZINC28637128 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288009 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCN(CC1)C(=O)c1ccccc1)C(=O)NO InChI=1S/C24H26N2O6S/c1-2-3-17-32-20-9-11-21(12-10-20)33(30,31)22(23(27)25-29)18-13-15-26(16-14-18)24(28)19-7-5-4-6-8-19/h4-12,18,22,29H,13-17H2,1H3,(H,25,27) CWGOBWMKFRWKPM-UHFFFAOYSA-N 50156719 2-(1-benzoyl-4-piperidinyl)-2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxyacetamide::CHEMBL384665 Disintegrin and metalloproteinase domain-containing protein 17 233 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156719&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10183692 104043828 CHEMBL384665 ZINC13586033 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288013 CCC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO InChI=1S/C24H27BrN2O5S/c1-2-3-4-17-32-21-9-11-22(12-10-21)33(30,31)24(23(28)26-29)13-15-27(16-14-24)18-19-5-7-20(25)8-6-19/h5-12,29H,2,13-18H2,1H3,(H,26,28) XMAZUULAIZPAJR-UHFFFAOYSA-N 50156724 1-(4-bromobenzyl)-4-(4-pent-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylicAcid hydroxyamide::CHEMBL225331 Disintegrin and metalloproteinase domain-containing protein 17 188 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156724&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9871823 104043833 CHEMBL225331 ZINC28636911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288022 CC#CCOc1ccc(SC(C2CCCCC2)C(=O)NO)cc1 InChI=1S/C18H23NO3S/c1-2-3-13-22-15-9-11-16(12-10-15)23-17(18(20)19-21)14-7-5-4-6-8-14/h9-12,14,17,21H,4-8,13H2,1H3,(H,19,20) ILUVAAMGYFXXGD-UHFFFAOYSA-N 50156696 2-{[4-(2-butynyloxy)phenyl]sulfanyl}-2-cyclohexyl-N-hydroxyacetamide::CHEMBL222992 Disintegrin and metalloproteinase domain-containing protein 17 105 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156696&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9945553 104043805 CHEMBL222992 ZINC13585996 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288023 COc1ccc(CN2CCC(CC2)(C(=O)NO)S(=O)(=O)c2ccc(OCC#CC)cc2)cc1 InChI=1S/C24H28N2O6S/c1-3-4-17-32-21-9-11-22(12-10-21)33(29,30)24(23(27)25-28)13-15-26(16-14-24)18-19-5-7-20(31-2)8-6-19/h5-12,28H,13-18H2,1-2H3,(H,25,27) QFAMXNMLWJDJPV-UHFFFAOYSA-N 50156722 4-(4-but-2-ynyloxybenzenesulfonyl)-1-(4-methoxybenzyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL222714 Disintegrin and metalloproteinase domain-containing protein 17 82 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156722&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9956465 104043831 CHEMBL222714 ZINC13586047 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288027 COc1ccc(cc1)C(C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C19H19NO6S/c1-3-4-13-26-16-9-11-17(12-10-16)27(23,24)18(19(21)20-22)14-5-7-15(25-2)8-6-14/h5-12,18,22H,13H2,1-2H3,(H,20,21) NOIOOWNKXMUESY-UHFFFAOYSA-N 50156699 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(4-methoxyphenyl)acetamide::CHEMBL222936 Disintegrin and metalloproteinase domain-containing protein 17 201 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156699&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11188429 104043808 CHEMBL222936 ZINC13585993 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288031 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO InChI=1S/C20H23BrN2O5S/c1-28-17-6-8-18(9-7-17)29(26,27)20(19(24)22-25)10-12-23(13-11-20)14-15-2-4-16(21)5-3-15/h2-9,25H,10-14H2,1H3,(H,22,24) YMQWZRPLMNNHEU-UHFFFAOYSA-N 50128669 1-(4-Bromo-benzyl)-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-(4-bromobenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-but-2-ynyloxyphenylsulfanyl)piperidine-4-carboxylic acid hydroxyamide::CHEMBL78255 Disintegrin and metalloproteinase domain-containing protein 17 72 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128669&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9869902 104020432 CHEMBL78255 ZINC13520983 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288042 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCN(CC1)OC(C)(C)C)C(=O)NO InChI=1S/C21H30N2O6S/c1-5-6-15-28-17-7-9-18(10-8-17)30(26,27)19(20(24)22-25)16-11-13-23(14-12-16)29-21(2,3)4/h7-10,16,19,25H,11-15H2,1-4H3,(H,22,24) VAQBMYMELLMZQZ-UHFFFAOYSA-N 50156702 CHEMBL221677::tert-butyl 4-[1-{[4-(2-butynyloxy)phenyl]sulfonyl}-2-(hydroxyamino)-2-oxoethyl]-1-piperidinecarboxylate Disintegrin and metalloproteinase domain-containing protein 17 190 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156702&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44421257 104043811 CHEMBL221677 ZINC34802403 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288043 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCS(=O)CC1)C(=O)NO InChI=1S/C17H21NO6S2/c1-2-3-10-24-14-4-6-15(7-5-14)26(22,23)16(17(19)18-20)13-8-11-25(21)12-9-13/h4-7,13,16,20H,8-12H2,1H3,(H,18,19) NPIXRIRDKCZNLD-UHFFFAOYSA-N 50156726 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-(1-oxidotetrahydro-4H-thiopyran-4-yl)acetamide::CHEMBL222303 Disintegrin and metalloproteinase domain-containing protein 17 39 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156726&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10179045 104043835 CHEMBL222303 ZINC13586016 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288045 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCSCC1)C(=O)NO InChI=1S/C17H21NO5S2/c1-2-3-10-23-14-4-6-15(7-5-14)25(21,22)16(17(19)18-20)13-8-11-24-12-9-13/h4-7,13,16,20H,8-12H2,1H3,(H,18,19) PSKIOMJBUJPQBG-UHFFFAOYSA-N 50156720 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-tetrahydro-2H-thiopyran-4-ylacetamide::CHEMBL426729 Disintegrin and metalloproteinase domain-containing protein 17 113 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156720&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10293348 104043829 CHEMBL426729 ZINC13586012 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288059 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)C(=O)NO InChI=1S/C23H29BrN2O5S/c1-2-3-16-31-20-8-10-21(11-9-20)32(29,30)23(22(27)25-28)12-14-26(15-13-23)17-18-4-6-19(24)7-5-18/h4-11,28H,2-3,12-17H2,1H3,(H,25,27) YJZSNVXLDDRADS-UHFFFAOYSA-N 50156718 1-(4-bromobenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL222934 Disintegrin and metalloproteinase domain-containing protein 17 72 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156718&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11386918 104043827 CHEMBL222934 ZINC13586039 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288063 ONC(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)S(=O)(=O)c1ccc(OCC#C)cc1 InChI=1S/C22H23BrN2O5S/c1-2-15-30-19-7-9-20(10-8-19)31(28,29)22(21(26)24-27)11-13-25(14-12-22)16-17-3-5-18(23)6-4-17/h1,3-10,27H,11-16H2,(H,24,26) SEFCVQRMTNTWJO-UHFFFAOYSA-N 50156714 1-(4-bromobenzyl)-4-(4-prop-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylicAcid hydroxyamide::CHEMBL221717 Disintegrin and metalloproteinase domain-containing protein 17 98 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156714&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9957875 104043823 CHEMBL221717 ZINC52971693 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288065 CCCCCCC(C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C18H25NO5S/c1-3-5-7-8-9-17(18(20)19-21)25(22,23)16-12-10-15(11-13-16)24-14-6-4-2/h10-13,17,21H,3,5,7-9,14H2,1-2H3,(H,19,20) TXIMSNHHNJBLTN-UHFFFAOYSA-N 50156716 2-(4-but-2-ynyloxybenzenelsulfonyl)octanoic acid hydroxamide::CHEMBL376314 Disintegrin and metalloproteinase domain-containing protein 17 75 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156716&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9842167 104043825 CHEMBL376314 ZINC13585944 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288070 CCCCCCC(Sc1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C18H25NO3S/c1-3-5-7-8-9-17(18(20)19-21)23-16-12-10-15(11-13-16)22-14-6-4-2/h10-13,17,21H,3,5,7-9,14H2,1-2H3,(H,19,20) HIBWRSXXRMHOLM-UHFFFAOYSA-N 50156727 2-(4-but-2-ynyloxyphenylsulfanyl)octanoic acid hydroxamide::CHEMBL223888 Disintegrin and metalloproteinase domain-containing protein 17 105 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156727&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9949603 104043836 CHEMBL223888 ZINC13585934 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288075 COc1ccc(cc1)C(Sc1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C19H19NO4S/c1-3-4-13-24-16-9-11-17(12-10-16)25-18(19(21)20-22)14-5-7-15(23-2)8-6-14/h5-12,18,22H,13H2,1-2H3,(H,20,21) VEMPUXZNKSUVFD-UHFFFAOYSA-N 50156721 2-{[4-(2-butynyloxy)phenyl]sulfanyl}-N-hydroxy-2-(4-methoxyphenyl)acetamide::CHEMBL373438 Disintegrin and metalloproteinase domain-containing protein 17 50 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156721&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11417011 104043830 CHEMBL373438 ZINC13585980 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288085 CC#CCOc1ccc(cc1)S(=O)(=O)C(C1CCOCC1)C(=O)NO InChI=1S/C17H21NO6S/c1-2-3-10-24-14-4-6-15(7-5-14)25(21,22)16(17(19)18-20)13-8-11-23-12-9-13/h4-7,13,16,20H,8-12H2,1H3,(H,18,19) IWSABXACJQMTBL-UHFFFAOYSA-N 50156710 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-N-hydroxy-2-tetrahydro-2H-pyran-4-ylacetamide::CHEMBL375013 Disintegrin and metalloproteinase domain-containing protein 17 51 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156710 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156710&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10133565 104043819 CHEMBL375013 ZINC13586008 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288088 CC#CCOc1ccc(cc1)S(=O)(=O)C(C(=O)NO)c1ccccc1 InChI=1S/C18H17NO5S/c1-2-3-13-24-15-9-11-16(12-10-15)25(22,23)17(18(20)19-21)14-7-5-4-6-8-14/h4-12,17,21H,13H2,1H3,(H,19,20) XWQYRXPGPDOWAJ-UHFFFAOYSA-N 50156704 2-{[4-(2-butynyloxy)phenyl]sulfonyl}-2-phenyl-N-hydroxyacetamide::CHEMBL222309 Disintegrin and metalloproteinase domain-containing protein 17 94 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156704&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11233687 104043813 CHEMBL222309 ZINC13585976 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288096 ONC(=O)C1(CCN(Cc2ccc(Br)cc2)CC1)S(=O)(=O)c1ccc(OCC#CCN2CCOCC2)cc1 InChI=1S/C27H32BrN3O6S/c28-23-5-3-22(4-6-23)21-31-14-11-27(12-15-31,26(32)29-33)38(34,35)25-9-7-24(8-10-25)37-18-2-1-13-30-16-19-36-20-17-30/h3-10,33H,11-21H2,(H,29,32) XKOVTPPNKADGLU-UHFFFAOYSA-N 50156728 1-(4-bromobenzyl)-4-[4-(4-morpholin-4-ylbut-2-ynyloxy)benzenesulfonyl]piperdine-4-carboxylic acid hydroxyamide::CHEMBL375318 Disintegrin and metalloproteinase domain-containing protein 17 882 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156728&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9960450 104043837 CHEMBL375318 ZINC28634922 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50288097 CC#CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccccc2)CC1)C(=O)NO InChI=1S/C23H26N2O5S/c1-2-3-17-30-20-9-11-21(12-10-20)31(28,29)23(22(26)24-27)13-15-25(16-14-23)18-19-7-5-4-6-8-19/h4-12,27H,13-18H2,1H3,(H,24,26) KRJQQXQOPZJOSC-UHFFFAOYSA-N 50156725 1-benzyl-4-(4-but-2-ynyloxybenzenesulfonyl)piperdine-4-carboxylic acid hydroxyamide::CHEMBL385312 Disintegrin and metalloproteinase domain-containing protein 17 90 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156725&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9803407 104043834 CHEMBL385312 ZINC13586043 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50287440 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1 NITYDPDXAAFEIT-DYVFJYSZSA-N 50062351 (R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N1-((S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE::CHEMBL19611::Ilomastat::US9487462, ilomastat Disintegrin and metalloproteinase domain-containing protein 17 7.5 ChEMBL 10.1016/j.bmcl.2004.09.082 10.7270/Q29Z94DH 15546732 Oh, M; Im, I; Lee, YJ; Kim, YH; Yoon, JH; Park, HG; Higashiyama, S; Kim, YC; Park, WJ Department of Life Science and National Research Laboratory of Proteolysis http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50062351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50062351&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search GM6 2DW1,2DW0,1PWU,2ERP,2E3X,4PKW 132519 103957874 CHEMBL19611 DB02255 ZINC03780014 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309067 Cc1ncccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C21H27N3O6S/c1-14-15(5-4-10-22-14)13-30-17-6-8-18(9-7-17)31(28,29)24-12-16(25)11-21(2,3)19(24)20(26)23-27/h4-10,16,19,25,27H,11-13H2,1-3H3,(H,23,26)/t16-,19+/m1/s1 AFKFHHGAXGELQR-APWZRJJASA-N 50167606 (2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-pyridin-3-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL192309 Disintegrin and metalloproteinase domain-containing protein 17 6.7 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167606&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399659 104052822 CHEMBL192309 ZINC28477695 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309068 Cc1ccc(F)cc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C22H27FN2O6S/c1-14-4-5-16(23)10-15(14)13-31-18-6-8-19(9-7-18)32(29,30)25-12-17(26)11-22(2,3)20(25)21(27)24-28/h4-10,17,20,26,28H,11-13H2,1-3H3,(H,24,27)/t17-,20+/m1/s1 MVPVFNYLHBJBHV-XLIONFOSSA-N 50167608 (2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL189052 Disintegrin and metalloproteinase domain-containing protein 17 7.3 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167608 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167608&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399635 104052824 CHEMBL189052 ZINC28471897 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309079 CC1(C)C[C@@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(Br)cc2)cc1 InChI=1S/C21H25BrN2O6S/c1-21(2)11-16(25)12-24(19(21)20(26)23-27)31(28,29)18-9-7-17(8-10-18)30-13-14-3-5-15(22)6-4-14/h3-10,16,19,25,27H,11-13H2,1-2H3,(H,23,26)/t16-,19+/m1/s1 UWPHCZNYIWQCKD-APWZRJJASA-N 50167618 (2R,5R)-1-[4-(4-Bromo-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL370312 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167618&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399733 104052834 CHEMBL370312 ZINC28474413 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309081 Cc1ccc(COc2ccc(cc2)S(=O)(=O)N2C[C@H](O)CC(C)(C)[C@@H]2C(=O)NO)cc1 InChI=1S/C22H28N2O6S/c1-15-4-6-16(7-5-15)14-30-18-8-10-19(11-9-18)31(28,29)24-13-17(25)12-22(2,3)20(24)21(26)23-27/h4-11,17,20,25,27H,12-14H2,1-3H3,(H,23,26)/t17-,20+/m1/s1 ZXORTEVXPYNWIB-XLIONFOSSA-N 50167619 (2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(4-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL191359 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167619&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399432 104052835 CHEMBL191359 ZINC28467538 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309083 CC1(C)C[C@@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2nccc3ccccc23)cc1 InChI=1S/C24H27N3O6S/c1-24(2)13-17(28)14-27(22(24)23(29)26-30)34(31,32)19-9-7-18(8-10-19)33-15-21-20-6-4-3-5-16(20)11-12-25-21/h3-12,17,22,28,30H,13-15H2,1-2H3,(H,26,29)/t17-,22+/m1/s1 XVBKVNVPXQZYQF-VGSWGCGISA-N 50167614 (2R,5R)-5-Hydroxy-1-[4-(isoquinolin-1-ylmethoxy)-benzenesulfonyl]-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL189975 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167614&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399665 104052830 CHEMBL189975 ZINC28471555 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309084 Cc1ccc(F)cc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC[C@@H]1C(=O)NO InChI=1S/C20H23FN2O6S/c1-13-2-3-15(21)10-14(13)12-29-17-5-7-18(8-6-17)30(27,28)23-11-16(24)4-9-19(23)20(25)22-26/h2-3,5-8,10,16,19,24,26H,4,9,11-12H2,1H3,(H,22,25)/t16-,19-/m1/s1 XQUSEXYSIGIEBX-VQIMIIECSA-N 50167620 (2R,5R)-1-[4-(5-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL191030 Disintegrin and metalloproteinase domain-containing protein 17 6.2 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167620&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399233 104052836 CHEMBL191030 ZINC03820645 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309086 CCc1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C23H30N2O6S/c1-4-16-7-5-6-8-17(16)15-31-19-9-11-20(12-10-19)32(29,30)25-14-18(26)13-23(2,3)21(25)22(27)24-28/h5-12,18,21,26,28H,4,13-15H2,1-3H3,(H,24,27)/t18-,21+/m1/s1 ZMDMPUVIZFSSCM-NQIIRXRSSA-N 50167610 (2R,5R)-1-[4-(2-Ethyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL189156 Disintegrin and metalloproteinase domain-containing protein 17 6.7 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167610&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399704 104052826 CHEMBL189156 ZINC28471970 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309093 CC1(C)C[C@@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccccc2Br)cc1 InChI=1S/C21H25BrN2O6S/c1-21(2)11-15(25)12-24(19(21)20(26)23-27)31(28,29)17-9-7-16(8-10-17)30-13-14-5-3-4-6-18(14)22/h3-10,15,19,25,27H,11-13H2,1-2H3,(H,23,26)/t15-,19+/m1/s1 MRBPTYYVXXZQBB-BEFAXECRSA-N 50167622 (2R,5R)-1-[4-(2-Bromo-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL372261 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399731 104052838 CHEMBL372261 ZINC28474167 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309103 Cc1nscc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C19H25N3O6S2/c1-12-13(11-29-21-12)10-28-15-4-6-16(7-5-15)30(26,27)22-9-14(23)8-19(2,3)17(22)18(24)20-25/h4-7,11,14,17,23,25H,8-10H2,1-3H3,(H,20,24)/t14-,17+/m1/s1 GTDCFHNWSMUQSI-PBHICJAKSA-N 50167623 (2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(3-methyl-isothiazol-4-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL434539 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167623&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399615 104052839 CHEMBL434539 ZINC28467845 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309111 CC1(C)C[C@@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2cccc(Br)c2)cc1 InChI=1S/C21H25BrN2O6S/c1-21(2)11-16(25)12-24(19(21)20(26)23-27)31(28,29)18-8-6-17(7-9-18)30-13-14-4-3-5-15(22)10-14/h3-10,16,19,25,27H,11-13H2,1-2H3,(H,23,26)/t16-,19+/m1/s1 YHIUMXFFZGJNGE-APWZRJJASA-N 50167624 (2R,5R)-1-[4-(3-Bromo-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL425009 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167624&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399597 104052840 CHEMBL425009 ZINC28475431 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309113 Cc1cc(F)ccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C22H27FN2O6S/c1-14-10-16(23)5-4-15(14)13-31-18-6-8-19(9-7-18)32(29,30)25-12-17(26)11-22(2,3)20(25)21(27)24-28/h4-10,17,20,26,28H,11-13H2,1-3H3,(H,24,27)/t17-,20+/m1/s1 LOMOBWUKCBVLNJ-XLIONFOSSA-N 50167605 (2R,5R)-1-[4-(4-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL190415 Disintegrin and metalloproteinase domain-containing protein 17 5.2 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167605&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399341 104052821 CHEMBL190415 ZINC28472506 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309115 CC1(C)C[C@@H](O)CN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(Cl)cc2Cl)cc1 InChI=1S/C21H24Cl2N2O6S/c1-21(2)10-15(26)11-25(19(21)20(27)24-28)32(29,30)17-7-5-16(6-8-17)31-12-13-3-4-14(22)9-18(13)23/h3-9,15,19,26,28H,10-12H2,1-2H3,(H,24,27)/t15-,19+/m1/s1 GBGAKFWYCGVPHY-BEFAXECRSA-N 50167609 (2R,5R)-1-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL179552 Disintegrin and metalloproteinase domain-containing protein 17 19 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167609 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167609&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11752434 104052825 CHEMBL179552 ZINC03817507 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309118 Cc1c(F)cccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C22H27FN2O6S/c1-14-15(5-4-6-19(14)23)13-31-17-7-9-18(10-8-17)32(29,30)25-12-16(26)11-22(2,3)20(25)21(27)24-28/h4-10,16,20,26,28H,11-13H2,1-3H3,(H,24,27)/t16-,20+/m1/s1 QEWCDBOSGBDOOY-UZLBHIALSA-N 50167617 (2R,5R)-1-[4-(3-Fluoro-2-methyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL189216 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167617&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399712 104052833 CHEMBL189216 ZINC28473202 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309122 Cc1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C22H28N2O6S/c1-15-6-4-5-7-16(15)14-30-18-8-10-19(11-9-18)31(28,29)24-13-17(25)12-22(2,3)20(24)21(26)23-27/h4-11,17,20,25,27H,12-14H2,1-3H3,(H,23,26)/t17-,20+/m1/s1 BHRJTBRTTVQRNI-XLIONFOSSA-N 50167613 (2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL190563 Disintegrin and metalloproteinase domain-containing protein 17 7.3 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167613&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399252 104052829 CHEMBL190563 ZINC28470881 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309125 Cc1cccc(COc2ccc(cc2)S(=O)(=O)N2C[C@H](O)CC(C)(C)[C@@H]2C(=O)NO)c1 InChI=1S/C22H28N2O6S/c1-15-5-4-6-16(11-15)14-30-18-7-9-19(10-8-18)31(28,29)24-13-17(25)12-22(2,3)20(24)21(26)23-27/h4-11,17,20,25,27H,12-14H2,1-3H3,(H,23,26)/t17-,20+/m1/s1 LQRPHHDGTPYXHT-XLIONFOSSA-N 50167621 (2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(3-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL192773 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167621&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399071 104052837 CHEMBL192773 ZINC28474040 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309126 CC(C)c1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C24H32N2O6S/c1-16(2)21-8-6-5-7-17(21)15-32-19-9-11-20(12-10-19)33(30,31)26-14-18(27)13-24(3,4)22(26)23(28)25-29/h5-12,16,18,22,27,29H,13-15H2,1-4H3,(H,25,28)/t18-,22+/m1/s1 DNUKGGCABDLAEO-GCJKJVERSA-N 50167612 (2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-benzenesulfonyl]-3,3-dimethyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL190441 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167612&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399451 104052828 CHEMBL190441 ZINC28470156 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50309128 Cc1cnsc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC(C)(C)[C@@H]1C(=O)NO InChI=1S/C19H25N3O6S2/c1-12-9-20-29-16(12)11-28-14-4-6-15(7-5-14)30(26,27)22-10-13(23)8-19(2,3)17(22)18(24)21-25/h4-7,9,13,17,23,25H,8,10-11H2,1-3H3,(H,21,24)/t13-,17+/m1/s1 MPWKVKMEMCVIDI-DYVFJYSZSA-N 50167616 (2R,5R)-5-Hydroxy-3,3-dimethyl-1-[4-(4-methyl-isothiazol-5-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL189107 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/j.bmcl.2005.03.105 10.7270/Q2BC3Z24 15911259 Noe, MC; Natarajan, V; Snow, SL; Mitchell, PG; Lopresti-Morrow, L; Reeves, LM; Yocum, SA; Carty, TJ; Barberia, JA; Sweeney, FJ; Liras, JL; Vaughn, M; Hardink, JR; Hawkins, JM; Tokar, C Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167616&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399559 104052832 CHEMBL189107 ZINC28473352 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50295299 CCC1CC(=O)N(c2ccc(Oc3ccccc3)cc2)C11C(=O)NC(=O)NC1=O InChI=1S/C21H19N3O5/c1-2-13-12-17(25)24(21(13)18(26)22-20(28)23-19(21)27)14-8-10-16(11-9-14)29-15-6-4-3-5-7-15/h3-11,13H,2,12H2,1H3,(H2,22,23,26,27,28) QBWALRVIJDSECI-UHFFFAOYSA-N 50160852 4-ethyl-1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone::CHEMBL361527 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.12.016 10.7270/Q2F47NN2 15686921 Kim, SH; Pudzianowski, AT; Leavitt, KJ; Barbosa, J; McDonnell, PA; Metzler, WJ; Rankin, BM; Liu, R; Vaccaro, W; Pitts, W Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160852 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160852&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11257884 104047312 CHEMBL361527 ZINC28128721 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50295303 COC(=O)c1ccc(Oc2ccc(cc2)N2C(=O)CCC22C(=O)NC(=O)NC2=O)cc1 InChI=1S/C21H17N3O7/c1-30-17(26)12-2-6-14(7-3-12)31-15-8-4-13(5-9-15)24-16(25)10-11-21(24)18(27)22-20(29)23-19(21)28/h2-9H,10-11H2,1H3,(H2,22,23,27,28,29) RAGDORVOHODYFH-UHFFFAOYSA-N 50160849 4-[4-(2,6,8,10-Tetraoxo-1,7,9-triaza-spiro[4.5]dec-1-yl)-phenoxy]-benzoic acid methyl ester::CHEMBL359716 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.12.016 10.7270/Q2F47NN2 15686921 Kim, SH; Pudzianowski, AT; Leavitt, KJ; Barbosa, J; McDonnell, PA; Metzler, WJ; Rankin, BM; Liu, R; Vaccaro, W; Pitts, W Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160849&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10025307 104047309 CHEMBL359716 ZINC28136379 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50295310 O=C1CCC2(N1c1ccc(Oc3ccccc3)cc1)C(=O)NC(=O)NC2=O InChI=1S/C19H15N3O5/c23-15-10-11-19(16(24)20-18(26)21-17(19)25)22(15)12-6-8-14(9-7-12)27-13-4-2-1-3-5-13/h1-9H,10-11H2,(H2,20,21,24,25,26) TVKGACNFKXXAEF-UHFFFAOYSA-N 50160847 1-(4-phenoxy-phenyl)-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone::CHEMBL178509 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.12.016 10.7270/Q2F47NN2 15686921 Kim, SH; Pudzianowski, AT; Leavitt, KJ; Barbosa, J; McDonnell, PA; Metzler, WJ; Rankin, BM; Liu, R; Vaccaro, W; Pitts, W Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160847&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25004194 104047307 CHEMBL178509 ZINC28132280 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50295319 OC(=O)c1ccc(Oc2ccc(cc2)N2C(=O)CCC22C(=O)NC(=O)NC2=O)cc1 InChI=1S/C20H15N3O7/c24-15-9-10-20(17(27)21-19(29)22-18(20)28)23(15)12-3-7-14(8-4-12)30-13-5-1-11(2-6-13)16(25)26/h1-8H,9-10H2,(H,25,26)(H2,21,22,27,28,29) JGGFVHVZVBWBKF-UHFFFAOYSA-N 50160851 4-[4-(2,6,8,10-Tetraoxo-1,7,9-triaza-spiro[4.5]dec-1-yl)-phenoxy]-benzoic acid::CHEMBL180275 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.12.016 10.7270/Q2F47NN2 15686921 Kim, SH; Pudzianowski, AT; Leavitt, KJ; Barbosa, J; McDonnell, PA; Metzler, WJ; Rankin, BM; Liu, R; Vaccaro, W; Pitts, W Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160851&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10047100 104047311 CHEMBL180275 ZINC28120026 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50295324 Clc1ccc(Oc2ccc(cc2)N2C(=O)CCC22C(=O)NC(=O)NC2=O)cc1 InChI=1S/C19H14ClN3O5/c20-11-1-5-13(6-2-11)28-14-7-3-12(4-8-14)23-15(24)9-10-19(23)16(25)21-18(27)22-17(19)26/h1-8H,9-10H2,(H2,21,22,25,26,27) FKICHBNUXJBKPB-UHFFFAOYSA-N 50160855 1-[4-(4-chloro-phenoxy)-phenyl]-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone::CHEMBL180616 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.12.016 10.7270/Q2F47NN2 15686921 Kim, SH; Pudzianowski, AT; Leavitt, KJ; Barbosa, J; McDonnell, PA; Metzler, WJ; Rankin, BM; Liu, R; Vaccaro, W; Pitts, W Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160855 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160855&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44389552 104047315 CHEMBL180616 ZINC28135981 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50295335 O=C1CCC2(N1c1ccc(Oc3ccc(Oc4ccccc4)cc3)cc1)C(=O)NC(=O)NC2=O InChI=1S/C25H19N3O6/c29-21-14-15-25(22(30)26-24(32)27-23(25)31)28(21)16-6-8-18(9-7-16)34-20-12-10-19(11-13-20)33-17-4-2-1-3-5-17/h1-13H,14-15H2,(H2,26,27,30,31,32) WKXRIMLOWDOHMN-UHFFFAOYSA-N 50160843 1-[4-(4-Phenoxy-phenoxy)-phenyl]-1,7,9-triaza-spiro[4.5]decane-2,6,8,10-tetraone::CHEMBL178163 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2004.12.016 10.7270/Q2F47NN2 15686921 Kim, SH; Pudzianowski, AT; Leavitt, KJ; Barbosa, J; McDonnell, PA; Metzler, WJ; Rankin, BM; Liu, R; Vaccaro, W; Pitts, W Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50160843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50160843&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44389401 104047303 CHEMBL178163 ZINC03819197 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300017 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)CCCN(C)C InChI=1S/C22H32N4O6S/c1-4-5-16-32-18-9-11-19(12-10-18)33(30,31)26-15-7-14-25(17-20(26)22(28)23-29)21(27)8-6-13-24(2)3/h9-12,20,29H,6-8,13-17H2,1-3H3,(H,23,28) OTDAXJIWZBAIMD-UHFFFAOYSA-N 50162732 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(4-dimethylamino-butyryl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL181110 Disintegrin and metalloproteinase domain-containing protein 17 75 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162732&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390338 104048847 CHEMBL181110 ZINC28344508 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300019 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CCC1C(=O)NO)C(=O)C(C)C InChI=1S/C20H27N3O6S/c1-4-5-14-29-16-6-8-17(9-7-16)30(27,28)23-13-12-22(20(25)15(2)3)11-10-18(23)19(24)21-26/h6-9,15,18,26H,10-14H2,1-3H3,(H,21,24) DOFYUNJDVUXVMB-UHFFFAOYSA-N 50162736 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-isobutyryl-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-isobutyryl-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL361959 Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162736&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390300 104048851 CHEMBL361959 ZINC28339924 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300021 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(Cc2ccccc2)CC1C(=O)NO InChI=1S/C23H27N3O5S/c1-2-3-16-31-20-10-12-21(13-11-20)32(29,30)26-15-7-14-25(18-22(26)23(27)24-28)17-19-8-5-4-6-9-19/h4-6,8-13,22,28H,7,14-18H2,1H3,(H,24,27) BLVHWPCGFOTRGU-UHFFFAOYSA-N 50162737 4-Benzyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL180333 Disintegrin and metalloproteinase domain-containing protein 17 61 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162737&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390323 104048852 CHEMBL180333 ZINC28339454 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300022 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(C)CCC1C(=O)NO InChI=1S/C17H23N3O5S/c1-3-4-13-25-14-5-7-15(8-6-14)26(23,24)20-12-11-19(2)10-9-16(20)17(21)18-22/h5-8,16,22H,9-13H2,1-2H3,(H,18,21) UNINFAIJOLFFHN-UHFFFAOYSA-N 50162733 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-methyl-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-methyl-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL180130 Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162733&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22644780 104048848 CHEMBL180130 ZINC28334644 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300023 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCS(=O)(=O)CC1C(=O)NO InChI=1S/C16H20N2O7S2/c1-2-3-10-25-13-5-7-14(8-6-13)27(23,24)18-9-4-11-26(21,22)12-15(18)16(19)17-20/h5-8,15,20H,4,9-12H2,1H3,(H,17,19) KEEWWGMUNANVLU-UHFFFAOYSA-N 50162734 4-(4-But-2-ynyloxy-benzenesulfonyl)-1,1-dioxo-1lambda*6*-[1,4]thiazepane-3-carboxylic acid hydroxyamide::CHEMBL180047 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162734&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390355 104048849 CHEMBL180047 ZINC28334525 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300025 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CCC1C(=O)NO)C(=O)c1ccccc1 InChI=1S/C23H25N3O6S/c1-2-3-17-32-19-9-11-20(12-10-19)33(30,31)26-16-15-25(14-13-21(26)22(27)24-29)23(28)18-7-5-4-6-8-18/h4-12,21,29H,13-17H2,1H3,(H,24,27) CCGWFLCBYDXLBZ-UHFFFAOYSA-N 50162738 1-Benzoyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::1-benzoyl-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1,4-diazepane-5-carboxamide::CHEMBL369302 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162738&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22644965 104048853 CHEMBL369302 ZINC28333925 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300027 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1cccs1 InChI=1S/C21H23N3O6S2/c1-2-3-13-30-16-7-9-17(10-8-16)32(28,29)24-12-5-11-23(15-18(24)20(25)22-27)21(26)19-6-4-14-31-19/h4,6-10,14,18,27H,5,11-13,15H2,1H3,(H,22,25) AXPBXFSDSKBQDG-UHFFFAOYSA-N 50162729 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2-carbonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL361809 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162729&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390391 104048844 CHEMBL361809 ZINC28127355 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300028 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCS(=O)(=O)CCC1C(=O)NO InChI=1S/C16H20N2O7S2/c1-2-3-10-25-13-4-6-14(7-5-13)27(23,24)18-9-12-26(21,22)11-8-15(18)16(19)17-20/h4-7,15,20H,8-12H2,1H3,(H,17,19) JKWHUKMFJPDCMY-UHFFFAOYSA-N 50162740 4-(4-But-2-ynyloxy-benzenesulfonyl)-1,1-dioxo-1lambda*6*-[1,4]thiazepane-5-carboxylic acid hydroxyamide::CHEMBL181328 Disintegrin and metalloproteinase domain-containing protein 17 19 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162740&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390245 104048855 CHEMBL181328 ZINC28331436 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300032 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(C)=O InChI=1S/C18H23N3O6S/c1-3-4-12-27-15-6-8-16(9-7-15)28(25,26)21-11-5-10-20(14(2)22)13-17(21)18(23)19-24/h6-9,17,24H,5,10-13H2,1-2H3,(H,19,23) VMMAOHBHWSKMLW-UHFFFAOYSA-N 50162730 4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL180891 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162730&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 20651317 104048845 CHEMBL180891 ZINC28339937 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300033 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)CN InChI=1S/C18H24N4O6S/c1-2-3-11-28-14-5-7-15(8-6-14)29(26,27)22-10-4-9-21(17(23)12-19)13-16(22)18(24)20-25/h5-8,16,25H,4,9-13,19H2,1H3,(H,20,24) MCUUTMPQGFSADF-UHFFFAOYSA-N 50162728 4-(2-Amino-acetyl)-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL180410 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162728 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162728&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390326 104048843 CHEMBL180410 ZINC28339487 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300034 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)S(C)(=O)=O InChI=1S/C17H23N3O7S2/c1-3-4-12-27-14-6-8-15(9-7-14)29(25,26)20-11-5-10-19(28(2,23)24)13-16(20)17(21)18-22/h6-9,16,22H,5,10-13H2,1-2H3,(H,18,21) RXYVRCSDLULANF-UHFFFAOYSA-N 50162744 1-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydroxy-4-methanesulfonyl-1,4-diazepane-2-carboxamide::CHEMBL181317 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162744 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162744&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390351 104048859 CHEMBL181317 ZINC28334487 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300041 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CCC1C(=O)NO)C(=O)OC(C)(C)C InChI=1S/C21H29N3O7S/c1-5-6-15-30-16-7-9-17(10-8-16)32(28,29)24-14-13-23(20(26)31-21(2,3)4)12-11-18(24)19(25)22-27/h7-10,18,27H,11-15H2,1-4H3,(H,22,25) JVVFIHLIADCISB-UHFFFAOYSA-N 50162742 4-(4-But-2-ynyloxy-benzenesulfonyl)-5-hydroxycarbamoyl-[1,4]diazepane-1-carboxylic acid tert-butyl ester::CHEMBL359502::tert-butyl 4-(4-(but-2-ynyloxy)phenylsulfonyl)-5-(hydroxycarbamoyl)-1,4-diazepane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 74 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162742&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22644837 104048857 CHEMBL359502 ZINC28344402 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300045 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCNCCC1C(=O)NO InChI=1S/C16H21N3O5S/c1-2-3-12-24-13-4-6-14(7-5-13)25(22,23)19-11-10-17-9-8-15(19)16(20)18-21/h4-7,15,17,21H,8-12H2,1H3,(H,18,20) FYYONZZUDPFMJO-UHFFFAOYSA-N 50162746 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL360257 Disintegrin and metalloproteinase domain-containing protein 17 24 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162746 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162746&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11394505 104048861 CHEMBL360257 ZINC13979105 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300051 COCC(=O)N1CCC(N(CC1)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C19H25N3O7S/c1-3-4-13-29-15-5-7-16(8-6-15)30(26,27)22-12-11-21(18(23)14-28-2)10-9-17(22)19(24)20-25/h5-8,17,25H,9-14H2,1-2H3,(H,20,24) VAMKUUUJVOOTKN-UHFFFAOYSA-N 50162745 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-(2-methoxyacetyl)-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-(2-methoxy-acetyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL178929 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162745 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162745&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390317 104048860 CHEMBL178929 ZINC28121887 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300052 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(Cc2ccccc2)CCC1C(=O)NO InChI=1S/C23H27N3O5S/c1-2-3-17-31-20-9-11-21(12-10-20)32(29,30)26-16-15-25(14-13-22(26)23(27)24-28)18-19-7-5-4-6-8-19/h4-12,22,28H,13-18H2,1H3,(H,24,27) CLTINYAXRIROMY-UHFFFAOYSA-N 50162731 1-Benzyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-5-carboxylic acid hydroxyamide::1-benzyl-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1,4-diazepane-5-carboxamide::CHEMBL183132 Disintegrin and metalloproteinase domain-containing protein 17 83 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162731&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22644970 104048846 CHEMBL183132 ZINC28342981 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300054 CCC(=O)N1CCC(N(CC1)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C19H25N3O6S/c1-3-5-14-28-15-6-8-16(9-7-15)29(26,27)22-13-12-21(18(23)4-2)11-10-17(22)19(24)20-25/h6-9,17,25H,4,10-14H2,1-2H3,(H,20,24) ROWNCZWVCCMTQI-UHFFFAOYSA-N 50162750 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-1-propionyl-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-propionyl-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL178732 Disintegrin and metalloproteinase domain-containing protein 17 19 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162750&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390299 104048865 CHEMBL178732 ZINC28128096 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300058 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(C)CC1C(=O)NO InChI=1S/C17H23N3O5S/c1-3-4-12-25-14-6-8-15(9-7-14)26(23,24)20-11-5-10-19(2)13-16(20)17(21)18-22/h6-9,16,22H,5,10-13H2,1-2H3,(H,18,21) MCYLJYADJGYSSU-UHFFFAOYSA-N 50162748 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methyl-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL181094 Disintegrin and metalloproteinase domain-containing protein 17 24 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162748 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162748&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390322 104048863 CHEMBL181094 ZINC28339447 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300059 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)c1ccccc1 InChI=1S/C23H25N3O6S/c1-2-3-16-32-19-10-12-20(13-11-19)33(30,31)26-15-7-14-25(17-21(26)22(27)24-29)23(28)18-8-5-4-6-9-18/h4-6,8-13,21,29H,7,14-17H2,1H3,(H,24,27) SMRKDKVRUIEVHG-UHFFFAOYSA-N 50162743 4-Benzoyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL180484 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162743&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10183755 104048858 CHEMBL180484 ZINC28338274 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300060 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSCCC1C(=O)NO InChI=1S/C16H20N2O5S2/c1-2-3-10-23-13-4-6-14(7-5-13)25(21,22)18-9-12-24-11-8-15(18)16(19)17-20/h4-7,15,20H,8-12H2,1H3,(H,17,19) KRUUUOUZTDKUCF-UHFFFAOYSA-N 50162741 4-(4-But-2-ynyloxy-benzenesulfonyl)-[1,4]thiazepane-5-carboxylic acid hydroxyamide::CHEMBL180181 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162741&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390289 104048856 CHEMBL180181 ZINC28335020 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300063 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCSCC1C(=O)NO InChI=1S/C16H20N2O5S2/c1-2-3-10-23-13-5-7-14(8-6-13)25(21,22)18-9-4-11-24-12-15(18)16(19)17-20/h5-8,15,20H,4,9-12H2,1H3,(H,17,19) UFYJMKIWYONTIU-UHFFFAOYSA-N 50162749 4-(4-But-2-ynyloxy-benzenesulfonyl)-[1,4]thiazepane-3-carboxylic acid hydroxyamide::CHEMBL362797 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162749 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162749&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22644895 104048864 CHEMBL362797 ZINC28343507 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300064 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)CNC(=O)OC(C)(C)C InChI=1S/C23H32N4O8S/c1-5-6-14-34-17-8-10-18(11-9-17)36(32,33)27-13-7-12-26(16-19(27)21(29)25-31)20(28)15-24-22(30)35-23(2,3)4/h8-11,19,31H,7,12-16H2,1-4H3,(H,24,30)(H,25,29) LKFNHCFYLDRUTH-UHFFFAOYSA-N 50162735 CHEMBL369574::{2-[4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-[1,4]diazepan-1-yl]-2-oxo-ethyl}-carbamic acid tert-butyl ester Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162735&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390314 104048850 CHEMBL369574 ZINC28136284 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300070 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCNCC1C(=O)NO InChI=1S/C16H21N3O5S/c1-2-3-11-24-13-5-7-14(8-6-13)25(22,23)19-10-4-9-17-12-15(19)16(20)18-21/h5-8,15,17,21H,4,9-12H2,1H3,(H,18,20) LFDHAXXLFUSQRL-UHFFFAOYSA-N 50162753 1-(4-But-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL359920 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162753 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162753&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390281 104048868 CHEMBL359920 ZINC28335797 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300072 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)NC#CC=CC#C InChI=1S/C23H24N4O6S/c1-3-5-7-8-14-24-23(29)26-15-9-16-27(21(18-26)22(28)25-30)34(31,32)20-12-10-19(11-13-20)33-17-6-4-2/h1,5,7,10-13,21,30H,9,15-18H2,2H3,(H,24,29)(H,25,28) PBCSMBZCRUWUMR-UHFFFAOYSA-N 50162754 4-(4-But-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-1,3-dicarboxylic acid 1-hex-3-ene-1,5-diynylamide 3-hydroxyamide::CHEMBL180627 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162754 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162754&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390258 104048869 CHEMBL180627 ZINC28344489 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300075 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)C(=O)OC(C)(C)C InChI=1S/C21H29N3O7S/c1-5-6-14-30-16-8-10-17(11-9-16)32(28,29)24-13-7-12-23(15-18(24)19(25)22-27)20(26)31-21(2,3)4/h8-11,18,27H,7,12-15H2,1-4H3,(H,22,25) DKBDATWDEJHFQS-UHFFFAOYSA-N 50162747 4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-[1,4]diazepane-1-carboxylic acid tert-butyl ester::CHEMBL180245 Disintegrin and metalloproteinase domain-containing protein 17 35 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162747 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162747&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390274 104048862 CHEMBL180245 ZINC28335466 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300077 CCN1CCC(N(CC1)S(=O)(=O)c1ccc(OCC#CC)cc1)C(=O)NO InChI=1S/C18H25N3O5S/c1-3-5-14-26-15-6-8-16(9-7-15)27(24,25)21-13-12-20(4-2)11-10-17(21)18(22)19-23/h6-9,17,23H,4,10-14H2,1-2H3,(H,19,22) KJFHTZIVTSKATM-UHFFFAOYSA-N 50162739 4-(4-(but-2-ynyloxy)phenylsulfonyl)-1-ethyl-N-hydroxy-1,4-diazepane-5-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-1-ethyl-[1,4]diazepane-5-carboxylic acid hydroxyamide::CHEMBL181208 Disintegrin and metalloproteinase domain-containing protein 17 37 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162739&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390356 104048854 CHEMBL181208 ZINC28334660 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300083 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCCN(CC1C(=O)NO)S(=O)(=O)c1ccccc1 InChI=1S/C22H25N3O7S2/c1-2-3-16-32-18-10-12-20(13-11-18)34(30,31)25-15-7-14-24(17-21(25)22(26)23-27)33(28,29)19-8-5-4-6-9-19/h4-6,8-13,21,27H,7,14-17H2,1H3,(H,23,26) YNTZVOSILJPSFZ-UHFFFAOYSA-N 50162752 4-Benzenesulfonyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL180197 Disintegrin and metalloproteinase domain-containing protein 17 68 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162752 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162752&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390304 104048867 CHEMBL180197 ZINC28340813 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50300084 CCCS(=O)(=O)N1CCCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C19H27N3O7S2/c1-3-5-13-29-16-7-9-17(10-8-16)31(27,28)22-12-6-11-21(30(25,26)14-4-2)15-18(22)19(23)20-24/h7-10,18,24H,4,6,11-15H2,1-2H3,(H,20,23) LVVFBDASYOIWFN-UHFFFAOYSA-N 50162751 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(propane-1-sulfonyl)-[1,4]diazepane-2-carboxylic acid hydroxyamide::CHEMBL181365 Disintegrin and metalloproteinase domain-containing protein 17 30 ChEMBL 10.1016/j.bmcl.2005.01.053 10.7270/Q2930SPX 15745814 Zask, A; Kaplan, J; Du, X; MacEwan, G; Sandanayaka, V; Eudy, N; Levin, J; Jin, G; Xu, J; Cummons, T; Barone, D; Ayral-Kaloustian, S; Skotnicki, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162751 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162751&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44390352 104048866 CHEMBL181365 ZINC34801925 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308855 Cc1cc(COc2ccc(cc2)C2(C)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C22H19N3O4/c1-13-11-14(17-5-3-4-6-18(17)23-13)12-29-16-9-7-15(8-10-16)22(2)19(26)24-21(28)25-20(22)27/h3-11H,12H2,1-2H3,(H2,24,25,26,27,28) QKXIBRKQCXPSEK-UHFFFAOYSA-N 50167485 5-Methyl-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::5-methyl-5-(4-((2-methylquinolin-4-yl)methoxy)phenyl)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL193316 Disintegrin and metalloproteinase domain-containing protein 17 1030 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167485&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10237492 104052720 CHEMBL193316 ZINC13980708 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308861 CCCCCCN1CCN(CC1)C1(C(=O)NC(=O)NC1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C31H37N5O4/c1-3-4-5-8-15-35-16-18-36(19-17-35)31(28(37)33-30(39)34-29(31)38)24-11-13-25(14-12-24)40-21-23-20-22(2)32-27-10-7-6-9-26(23)27/h6-7,9-14,20H,3-5,8,15-19,21H2,1-2H3,(H2,33,34,37,38,39) CKPNTYRTTDOFLD-UHFFFAOYSA-N 50167488 5-(4-Hexyl-piperazin-1-yl)-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL371199 Disintegrin and metalloproteinase domain-containing protein 17 81.0 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167488 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167488&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10289607 104052723 CHEMBL371199 ZINC23254589 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308864 CC1(C(=O)NC(=O)NC1=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C18H16N2O4/c1-18(15(21)19-17(23)20-16(18)22)13-7-9-14(10-8-13)24-11-12-5-3-2-4-6-12/h2-10H,11H2,1H3,(H2,19,20,21,22,23) LAHYEFDNWASMJY-UHFFFAOYSA-N 50167489 5-(4-Benzyloxy-phenyl)-5-methyl-pyrimidine-2,4,6-trione::CHEMBL373311 Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167489 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167489&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399312 104052724 CHEMBL373311 ZINC28477089 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308870 Cc1cc(COc2ccc3cc(ccc3c2)C2(C)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C26H21N3O4/c1-15-11-18(21-5-3-4-6-22(21)27-15)14-33-20-10-8-16-12-19(9-7-17(16)13-20)26(2)23(30)28-25(32)29-24(26)31/h3-13H,14H2,1-2H3,(H2,28,29,30,31,32) HYJDMXKMWHHPTM-UHFFFAOYSA-N 50167496 5-Methyl-5-[6-(2-methyl-quinolin-4-ylmethoxy)-naphthalen-2-yl]-pyrimidine-2,4,6-trione::CHEMBL366060 Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167496 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167496&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399509 104052731 CHEMBL366060 ZINC28470098 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308871 CN1CCN(CC1)C1(C(=O)NC(=O)NC1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H27N5O4/c1-17-15-18(21-5-3-4-6-22(21)27-17)16-35-20-9-7-19(8-10-20)26(31-13-11-30(2)12-14-31)23(32)28-25(34)29-24(26)33/h3-10,15H,11-14,16H2,1-2H3,(H2,28,29,32,33,34) HNINPFHHNYDBSH-UHFFFAOYSA-N 50167486 5-(4-Methyl-piperazin-1-yl)-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::5-(4-methylpiperazin-1-yl)-5-(4-((2-methylquinolin-4-yl)methoxy)phenyl)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL193084 Disintegrin and metalloproteinase domain-containing protein 17 91 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167486 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167486&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10127889 104052721 CHEMBL193084 ZINC23247638 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308873 Cc1cc(COc2ccc(cc2)C2(N3CCCCC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C26H26N4O4/c1-17-15-18(21-7-3-4-8-22(21)27-17)16-34-20-11-9-19(10-12-20)26(30-13-5-2-6-14-30)23(31)28-25(33)29-24(26)32/h3-4,7-12,15H,2,5-6,13-14,16H2,1H3,(H2,28,29,31,32,33) CPNHPERKWKQFHI-UHFFFAOYSA-N 50167491 5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-piperidin-1-yl-pyrimidine-2,4,6-trione::CHEMBL372659 Disintegrin and metalloproteinase domain-containing protein 17 855.0 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167491 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167491&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10127629 104052726 CHEMBL372659 ZINC28475713 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308874 CC(C)N1CCN(CC1)C1(C(=O)NC(=O)NC1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C28H31N5O4/c1-18(2)32-12-14-33(15-13-32)28(25(34)30-27(36)31-26(28)35)21-8-10-22(11-9-21)37-17-20-16-19(3)29-24-7-5-4-6-23(20)24/h4-11,16,18H,12-15,17H2,1-3H3,(H2,30,31,34,35,36) INGVNDTUNOZHOP-UHFFFAOYSA-N 50167492 5-(4-Isopropyl-piperazin-1-yl)-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL190936 Disintegrin and metalloproteinase domain-containing protein 17 96 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167492 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167492&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10128313 104052727 CHEMBL190936 ZINC23247646 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308876 Cc1cc(COc2ccc(cc2)C2(N3CCN(CC3)C(=O)OC(C)(C)C)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C30H33N5O6/c1-19-17-20(23-7-5-6-8-24(23)31-19)18-40-22-11-9-21(10-12-22)30(25(36)32-27(38)33-26(30)37)35-15-13-34(14-16-35)28(39)41-29(2,3)4/h5-12,17H,13-16,18H2,1-4H3,(H2,32,33,36,37,38) MUEJBYPIDLKGKN-UHFFFAOYSA-N 50167490 4-{5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-2,4,6-trioxo-hexahydro-pyrimidin-5-yl}-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL365386 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167490 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167490&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10128916 104052725 CHEMBL365386 ZINC28468451 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308879 Cc1cc(COc2ccc(cc2)C2(N3CCN(CC(C)(C)C)CC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C30H35N5O4/c1-20-17-21(24-7-5-6-8-25(24)31-20)18-39-23-11-9-22(10-12-23)30(26(36)32-28(38)33-27(30)37)35-15-13-34(14-16-35)19-29(2,3)4/h5-12,17H,13-16,18-19H2,1-4H3,(H2,32,33,36,37,38) ZWTFDOKRWKJVER-UHFFFAOYSA-N 50167487 5-[4-(2,2-Dimethyl-propyl)-piperazin-1-yl]-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL360193 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167487&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10128659 104052722 CHEMBL360193 ZINC28471934 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308885 Cc1cc(COc2ccc(cc2)C2(N3CCN(CCCc4ccccc4)CC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C34H35N5O4/c1-24-22-26(29-11-5-6-12-30(29)35-24)23-43-28-15-13-27(14-16-28)34(31(40)36-33(42)37-32(34)41)39-20-18-38(19-21-39)17-7-10-25-8-3-2-4-9-25/h2-6,8-9,11-16,22H,7,10,17-21,23H2,1H3,(H2,36,37,40,41,42) WOGNSQDLIXXYFU-UHFFFAOYSA-N 50167495 5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-[4-(3-phenyl-propyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione::CHEMBL373154 Disintegrin and metalloproteinase domain-containing protein 17 110 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167495 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167495&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10175210 104052730 CHEMBL373154 ZINC28475843 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308891 CC(=O)c1ccc(cc1)N1CCN(CC1)C1(C(=O)NC(=O)NC1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C33H31N5O5/c1-21-19-24(28-5-3-4-6-29(28)34-21)20-43-27-13-9-25(10-14-27)33(30(40)35-32(42)36-31(33)41)38-17-15-37(16-18-38)26-11-7-23(8-12-26)22(2)39/h3-14,19H,15-18,20H2,1-2H3,(H2,35,36,40,41,42) JXUDAYOKNXBKHH-UHFFFAOYSA-N 50167500 5-[4-(4-Acetyl-phenyl)-piperazin-1-yl]-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL192204 Disintegrin and metalloproteinase domain-containing protein 17 620 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167500&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399555 104052735 CHEMBL192204 ZINC28473630 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308900 Cc1cc(COc2ccc(cc2)C2(N3CCN(Cc4ccccc4)CC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C32H31N5O4/c1-22-19-24(27-9-5-6-10-28(27)33-22)21-41-26-13-11-25(12-14-26)32(29(38)34-31(40)35-30(32)39)37-17-15-36(16-18-37)20-23-7-3-2-4-8-23/h2-14,19H,15-18,20-21H2,1H3,(H2,34,35,38,39,40) WZUCVDGGDSHNQU-UHFFFAOYSA-N 50167499 5-(4-Benzyl-piperazin-1-yl)-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL371781 Disintegrin and metalloproteinase domain-containing protein 17 195 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167499 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167499&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10239716 104052734 CHEMBL371781 ZINC23254512 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308906 Cc1cc(COc2ccc(cc2)C2(N3CCN(CC3)c3ccc(cc3)[N+]([O-])=O)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C31H28N6O6/c1-20-18-21(26-4-2-3-5-27(26)32-20)19-43-25-12-6-22(7-13-25)31(28(38)33-30(40)34-29(31)39)36-16-14-35(15-17-36)23-8-10-24(11-9-23)37(41)42/h2-13,18H,14-17,19H2,1H3,(H2,33,34,38,39,40) CEGUOXMMRKISPK-UHFFFAOYSA-N 50167483 5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-[4-(4-nitro-phenyl)-piperazin-1-yl]-pyrimidine-2,4,6-trione::CHEMBL190215 Disintegrin and metalloproteinase domain-containing protein 17 2800 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167483 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167483&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10312141 104052718 CHEMBL190215 ZINC28468113 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308918 Cc1cc(COc2ccc(cc2)C2(N3CCN(CC3)S(C)(=O)=O)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C26H27N5O6S/c1-17-15-18(21-5-3-4-6-22(21)27-17)16-37-20-9-7-19(8-10-20)26(23(32)28-25(34)29-24(26)33)30-11-13-31(14-12-30)38(2,35)36/h3-10,15H,11-14,16H2,1-2H3,(H2,28,29,32,33,34) HEICZDBUMBAABJ-UHFFFAOYSA-N 50167498 5-(4-Methanesulfonyl-piperazin-1-yl)-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL191360 Disintegrin and metalloproteinase domain-containing protein 17 275 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167498&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10289551 104052733 CHEMBL191360 ZINC28468448 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308919 Cc1cc(COc2ccc(cc2)C2(N3CCNCC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C25H25N5O4/c1-16-14-17(20-4-2-3-5-21(20)27-16)15-34-19-8-6-18(7-9-19)25(30-12-10-26-11-13-30)22(31)28-24(33)29-23(25)32/h2-9,14,26H,10-13,15H2,1H3,(H2,28,29,31,32,33) VIJGBSAWWJKQHY-UHFFFAOYSA-N 50167484 5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-piperazin-1-yl-pyrimidine-2,4,6-trione::CHEMBL363719 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167484&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10173876 104052719 CHEMBL363719 ZINC28472157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308922 Cc1cc(COc2ccc(cc2)C2(N3CCOCC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C25H24N4O5/c1-16-14-17(20-4-2-3-5-21(20)26-16)15-34-19-8-6-18(7-9-19)25(29-10-12-33-13-11-29)22(30)27-24(32)28-23(25)31/h2-9,14H,10-13,15H2,1H3,(H2,27,28,30,31,32) BKBMJVASMYYCKO-UHFFFAOYSA-N 50167497 5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-morpholin-4-yl-pyrimidine-2,4,6-trione::CHEMBL189591 Disintegrin and metalloproteinase domain-containing protein 17 535.0 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167497 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167497&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10127670 104052732 CHEMBL189591 ZINC28472669 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308925 CC1(C(=O)NC(=O)NC1=O)c1ccc(O)cc1 InChI=1S/C11H10N2O4/c1-11(6-2-4-7(14)5-3-6)8(15)12-10(17)13-9(11)16/h2-5,14H,1H3,(H2,12,13,15,16,17) XTJZQNUILYKCRX-UHFFFAOYSA-N 50167493 5-(4-Hydroxy-phenyl)-5-methyl-pyrimidine-2,4,6-trione::CHEMBL191076 Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167493 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167493&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399294 104052728 CHEMBL191076 ZINC28465514 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308930 Cc1cc(COc2ccc(cc2)C2(N3CCN(CC3)C(=O)C(C)(C)C)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C30H33N5O5/c1-19-17-20(23-7-5-6-8-24(23)31-19)18-40-22-11-9-21(10-12-22)30(25(36)32-28(39)33-26(30)37)35-15-13-34(14-16-35)27(38)29(2,3)4/h5-12,17H,13-16,18H2,1-4H3,(H2,32,33,36,37,39) NPIWTBAYANSBHN-UHFFFAOYSA-N 50167501 5-[4-(2,2-Dimethyl-propionyl)-piperazin-1-yl]-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::CHEMBL365167 Disintegrin and metalloproteinase domain-containing protein 17 5400 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167501 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167501&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10196425 104052736 CHEMBL365167 ZINC28473633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50308933 Cc1cc(COc2ccc(cc2)C2(N3CCN(CCc4ccccc4)CC3)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C33H33N5O4/c1-23-21-25(28-9-5-6-10-29(28)34-23)22-42-27-13-11-26(12-14-27)33(30(39)35-32(41)36-31(33)40)38-19-17-37(18-20-38)16-15-24-7-3-2-4-8-24/h2-14,21H,15-20,22H2,1H3,(H2,35,36,39,40,41) OCBYWAVDKLDIDI-UHFFFAOYSA-N 50167494 5-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-5-(4-phenethyl-piperazin-1-yl)-pyrimidine-2,4,6-trione::CHEMBL193945 Disintegrin and metalloproteinase domain-containing protein 17 84.0 ChEMBL 10.1016/j.bmcl.2005.04.039 10.7270/Q2028R2B 15908214 Duan, JJ; Lu, Z; Wasserman, ZR; Liu, RQ; Covington, MB; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167494 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167494&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10311997 104052729 CHEMBL193945 ZINC28476041 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50320055 COc1c(Br)ccc2oc(C(=O)Nc3ccc(cc3)-c3ccc(cc3)S(=O)(=O)N[C@@H](C(C)C)C(O)=O)c(C)c12 InChI=1S/C28H27BrN2O7S/c1-15(2)24(28(33)34)31-39(35,36)20-11-7-18(8-12-20)17-5-9-19(10-6-17)30-27(32)25-16(3)23-22(38-25)14-13-21(29)26(23)37-4/h5-15,24,31H,1-4H3,(H,30,32)(H,33,34)/t24-/m0/s1 HHHAELOQIYTSIY-DEOSSOPVSA-N 50173223 (S)-2-(4'-(5-bromo-4-methoxy-3-methylbenzofuran-2-carboxamido)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid::(S)-2-{4'-[(5-Bromo-4-methoxy-3-methyl-benzofuran-2-carbonyl)-amino]-biphenyl-4-sulfonylamino}-3-methyl-butyric acid::CHEMBL198262 Disintegrin and metalloproteinase domain-containing protein 17 34000 ChEMBL 10.1016/j.bmcl.2005.08.001 10.7270/Q20Z72TH 16153831 Li, J; Rush, TS; Li, W; DeVincentis, D; Du, X; Hu, Y; Thomason, JR; Xiang, JS; Skotnicki, JS; Tam, S; Cunningham, KM; Chockalingam, PS; Morris, EA; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11284983 104059194 CHEMBL198262 ZINC28528569 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50328161 Cc1cc(COc2ccc(CCN3C(CCS3(=O)=O)C(=O)NO)cc2)c2ccccc2n1 InChI=1S/C23H25N3O5S/c1-16-14-18(20-4-2-3-5-21(20)24-16)15-31-19-8-6-17(7-9-19)10-12-26-22(23(27)25-28)11-13-32(26,29)30/h2-9,14,22,28H,10-13,15H2,1H3,(H,25,27) OZLFXWYCUHTSQI-UHFFFAOYSA-N 50177311 2-{2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-ethyl}-1,1-dioxo-isothiazolidine-3-carboxylic acid hydroxyamide::CHEMBL204549 Disintegrin and metalloproteinase domain-containing protein 17 480 ChEMBL 10.1016/j.bmcl.2005.10.078 10.7270/Q26Q1WTM 16289878 Cherney, RJ; King, BW; Gilmore, JL; Liu, RQ; Covington, MB; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177311 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177311&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10161391 104062779 CHEMBL204549 ZINC28569532 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50328174 Cc1cc(COc2ccc(cc2)N2C(CNS2(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C20H20N4O5S/c1-13-10-14(17-4-2-3-5-18(17)22-13)12-29-16-8-6-15(7-9-16)24-19(20(25)23-26)11-21-30(24,27)28/h2-10,19,21,26H,11-12H2,1H3,(H,23,25) IGMJBXNPPIZSAX-UHFFFAOYSA-N 50177314 2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-[1,2,5]thiadiazolidine-3-carboxylic acid hydroxyamide::CHEMBL379469 Disintegrin and metalloproteinase domain-containing protein 17 8.3 ChEMBL 10.1016/j.bmcl.2005.10.078 10.7270/Q26Q1WTM 16289878 Cherney, RJ; King, BW; Gilmore, JL; Liu, RQ; Covington, MB; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177314&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10159633 104062782 CHEMBL379469 ZINC03817890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50328180 Cc1cc(COc2ccc(CN3C(CCS3(=O)=O)C(=O)NO)cc2)c2ccccc2n1 InChI=1S/C22H23N3O5S/c1-15-12-17(19-4-2-3-5-20(19)23-15)14-30-18-8-6-16(7-9-18)13-25-21(22(26)24-27)10-11-31(25,28)29/h2-9,12,21,27H,10-11,13-14H2,1H3,(H,24,26) JHHLVVDASBMHIL-UHFFFAOYSA-N 50177312 2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzyl]-1,1-dioxo-isothiazolidine-3-carboxylic acid hydroxyamide::CHEMBL204495 Disintegrin and metalloproteinase domain-containing protein 17 900 ChEMBL 10.1016/j.bmcl.2005.10.078 10.7270/Q26Q1WTM 16289878 Cherney, RJ; King, BW; Gilmore, JL; Liu, RQ; Covington, MB; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177312&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10203685 104062780 CHEMBL204495 ZINC03817886 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50328183 Cc1cc(COc2ccc(cc2)N2C(CCS2(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C21H21N3O5S/c1-14-12-15(18-4-2-3-5-19(18)22-14)13-29-17-8-6-16(7-9-17)24-20(21(25)23-26)10-11-30(24,27)28/h2-9,12,20,26H,10-11,13H2,1H3,(H,23,25) CNJHNAILYAGVJU-UHFFFAOYSA-N 50177310 2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-isothiazolidine-3-carboxylic acid hydroxyamide::CHEMBL204048 Disintegrin and metalloproteinase domain-containing protein 17 5.9 ChEMBL 10.1016/j.bmcl.2005.10.078 10.7270/Q26Q1WTM 16289878 Cherney, RJ; King, BW; Gilmore, JL; Liu, RQ; Covington, MB; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177310 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177310&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10202769 104062778 CHEMBL204048 ZINC28570887 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50328184 Cc1cc(COc2ccc(CC3C(CCS3(=O)=O)C(=O)NO)cc2)c2ccccc2n1 InChI=1S/C23H24N2O5S/c1-15-12-17(19-4-2-3-5-21(19)24-15)14-30-18-8-6-16(7-9-18)13-22-20(23(26)25-27)10-11-31(22,28)29/h2-9,12,20,22,27H,10-11,13-14H2,1H3,(H,25,26) BZIUKEPVFXHVPZ-UHFFFAOYSA-N 50177313 2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzyl]-1,1-dioxo-tetrahydro-thiophene-3-carboxylic acid hydroxyamide::CHEMBL203972 Disintegrin and metalloproteinase domain-containing protein 17 150 ChEMBL 10.1016/j.bmcl.2005.10.078 10.7270/Q26Q1WTM 16289878 Cherney, RJ; King, BW; Gilmore, JL; Liu, RQ; Covington, MB; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177313&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22341241 104062781 CHEMBL203972 ZINC28570435 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50328188 COc1ccc(cc1)-c1ccc(CN2C(CCS2(=O)=O)C(=O)NO)cc1 InChI=1S/C18H20N2O5S/c1-25-16-8-6-15(7-9-16)14-4-2-13(3-5-14)12-20-17(18(21)19-22)10-11-26(20,23)24/h2-9,17,22H,10-12H2,1H3,(H,19,21) RNCWXNOSFWYLTA-UHFFFAOYSA-N 11548 CHEMBL100570::N-hydroxy-2-[(4-methoxy-1,1-biphenyl-4-yl)methyl]isothiazolidine-3-carboxamide 1,1-dioxide::N-hydroxy-2-{[4-(4-methoxyphenyl)phenyl]methyl}-1,1-dioxo-1,2-thiazolidine-3-carboxamide::Sultam Hydroxamate 15a Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2005.10.078 10.7270/Q26Q1WTM 16289878 Cherney, RJ; King, BW; Gilmore, JL; Liu, RQ; Covington, MB; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11548&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10156375 46512081 CHEMBL100570 ZINC13579358 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50328191 Cc1cc(COc2ccc(cc2)N2C(CCCS2(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C22H23N3O5S/c1-15-13-16(19-5-2-3-6-20(19)23-15)14-30-18-10-8-17(9-11-18)25-21(22(26)24-27)7-4-12-31(25,28)29/h2-3,5-6,8-11,13,21,27H,4,7,12,14H2,1H3,(H,24,26) XVLVIDNHSWHJBN-UHFFFAOYSA-N 50177315 2-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-1lambda*6*-[1,2]thiazinane-3-carboxylic acid hydroxyamide::2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-[1,2]thiazinane-3-carboxylic acid hydroxyamide::CHEMBL203160 Disintegrin and metalloproteinase domain-containing protein 17 3.7 ChEMBL 10.1016/j.bmcl.2005.10.078 10.7270/Q26Q1WTM 16289878 Cherney, RJ; King, BW; Gilmore, JL; Liu, RQ; Covington, MB; Duan, JJ; Decicco, CP Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177315&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10225319 104062783 CHEMBL203160 ZINC28570889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316388 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCNCC1C(=O)NO InChI=1S/C15H19N3O5S/c1-2-3-10-23-12-4-6-13(7-5-12)24(21,22)18-9-8-16-11-14(18)15(19)17-20/h4-7,14,16,20H,8-11H2,1H3,(H,17,19) ZTVJLUOPMWIKSV-UHFFFAOYSA-N 50171534 1-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL436324 Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171534&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9798637 104057731 CHEMBL436324 ZINC28525784 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316412 CCCCC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C20H27N3O6S/c1-3-5-7-19(24)22-12-13-23(18(15-22)20(25)21-26)30(27,28)17-10-8-16(9-11-17)29-14-6-4-2/h8-11,18,26H,3,5,7,12-15H2,1-2H3,(H,21,25) CYIOQNVVHKTYRH-UHFFFAOYSA-N 50171544 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pentanoyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL198100 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171544&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44404761 104057741 CHEMBL198100 ZINC28528042 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316413 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(=O)c1cccs1 InChI=1S/C20H21N3O6S2/c1-2-3-12-29-15-6-8-16(9-7-15)31(27,28)23-11-10-22(14-17(23)19(24)21-26)20(25)18-5-4-13-30-18/h4-9,13,17,26H,10-12,14H2,1H3,(H,21,24) QFTWPDUNHCKGKX-UHFFFAOYSA-N 50171537 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-(thiophene-2-carbonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL381224 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171537&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9912235 104057734 CHEMBL381224 ZINC28528216 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316419 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(Cc2cccnc2)CC1C(=O)NO InChI=1S/C21H24N4O5S/c1-2-3-13-30-18-6-8-19(9-7-18)31(28,29)25-12-11-24(16-20(25)21(26)23-27)15-17-5-4-10-22-14-17/h4-10,14,20,27H,11-13,15-16H2,1H3,(H,23,26) YCIYENASUWAOBH-UHFFFAOYSA-N 50171545 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-pyridin-3-ylmethyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL194627 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171545&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9955127 104057742 CHEMBL194627 ZINC28526223 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316435 COC(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C17H21N3O7S/c1-3-4-11-27-13-5-7-14(8-6-13)28(24,25)20-10-9-19(17(22)26-2)12-15(20)16(21)18-23/h5-8,15,23H,9-12H2,1-2H3,(H,18,21) XRGWUGBXRHDGDG-UHFFFAOYSA-N 50171540 4-(4-But-2-ynyloxy-benzenesulfonyl)-3-hydroxycarbamoyl-piperazine-1-carboxylic acid methyl ester::CHEMBL372908 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171540&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9887831 104057737 CHEMBL372908 ZINC28526807 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316438 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC2(CCCC2)C1C(=O)NO InChI=1S/C19H24N2O5S2/c1-2-3-13-26-15-6-8-16(9-7-15)28(24,25)21-12-14-27-19(10-4-5-11-19)17(21)18(22)20-23/h6-9,17,23H,4-5,10-14H2,1H3,(H,20,22) LMASIGSKSCEZDY-UHFFFAOYSA-N 50171541 9-(4-But-2-ynyloxy-benzenesulfonyl)-6-thia-9-aza-spiro[4.5]decane-10-carboxylic acid hydroxyamide::CHEMBL434187 Disintegrin and metalloproteinase domain-containing protein 17 43 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171541&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9954117 104057738 CHEMBL434187 ZINC28527681 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316442 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)S(C)(=O)=O InChI=1S/C16H21N3O7S2/c1-3-4-11-26-13-5-7-14(8-6-13)28(24,25)19-10-9-18(27(2,22)23)12-15(19)16(20)17-21/h5-8,15,21H,9-12H2,1-2H3,(H,17,20) VRUQYJXYEALKCT-UHFFFAOYSA-N 50171536 1-(4-But-2-ynyloxy-benzenesulfonyl)-4-methanesulfonyl-piperazine-2-carboxylic acid hydroxyamide::CHEMBL194237 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171536&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9867411 104057733 CHEMBL194237 ZINC28526809 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316447 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSCC1C(=O)NO InChI=1S/C15H18N2O5S2/c1-2-3-9-22-12-4-6-13(7-5-12)24(20,21)17-8-10-23-11-14(17)15(18)16-19/h4-7,14,19H,8-11H2,1H3,(H,16,18) KQEHQRICYJKJLB-UHFFFAOYSA-N 50171539 4-(4-But-2-ynyloxy-benzenesulfonyl)-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL370129 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171539&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9842332 104057736 CHEMBL370129 ZINC28525999 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316450 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCOCC1C(=O)NO InChI=1S/C15H18N2O6S/c1-2-3-9-23-12-4-6-13(7-5-12)24(20,21)17-8-10-22-11-14(17)15(18)16-19/h4-7,14,19H,8-11H2,1H3,(H,16,18) SEOIKBYFTLCBTF-UHFFFAOYSA-N 50171538 4-(4-But-2-ynyloxy-benzenesulfonyl)-morpholine-3-carboxylic acid hydroxyamide::CHEMBL196092 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171538&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9819974 104057735 CHEMBL196092 ZINC28525997 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316460 CCN(CC)C(=O)N1CCN(C(C1)C(=O)NO)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C20H28N4O6S/c1-4-7-14-30-16-8-10-17(11-9-16)31(28,29)24-13-12-23(15-18(24)19(25)21-27)20(26)22(5-2)6-3/h8-11,18,27H,5-6,12-15H2,1-3H3,(H,21,25) SQODILRODCBOCF-UHFFFAOYSA-N 50171542 4-(4-But-2-ynyloxy-benzenesulfonyl)-piperazine-1,3-dicarboxylic acid 1-diethylamide 3-hydroxyamide::CHEMBL370825 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171542&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868490 104057739 CHEMBL370825 ZINC28528953 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316472 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCN(CC1C(=O)NO)C(C)=O InChI=1S/C17H21N3O6S/c1-3-4-11-26-14-5-7-15(8-6-14)27(24,25)20-10-9-19(13(2)21)12-16(20)17(22)18-23/h5-8,16,23H,9-12H2,1-2H3,(H,18,22) VJCSPSPTFYXXJB-UHFFFAOYSA-N 50171535 4-Acetyl-1-(4-but-2-ynyloxy-benzenesulfonyl)-piperazine-2-carboxylic acid hydroxyamide::CHEMBL195948 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171535&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9908681 104057732 CHEMBL195948 ZINC28526076 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50316473 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)C1C(=O)NO InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,10-12H2,1-3H3,(H,18,20) CVZIHNYAZLXRRS-UHFFFAOYSA-N 50171543 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-2,2-dimethyl-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL382975 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2005.06.072 10.7270/Q2WH2PHM 16084720 Levin, JI; Chen, JM; Laakso, LM; Du, M; Du, X; Venkatesan, AM; Sandanayaka, V; Zask, A; Xu, J; Xu, W; Zhang, Y; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171543&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search IH6 1ZXC 6323382 104057740 CHEMBL382975 ZINC28527693 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339949 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCOCC2)c2ccccc2n1 InChI=1S/C25H27N3O5/c1-17-14-19(21-4-2-3-5-22(21)26-17)16-33-20-8-6-18(7-9-20)24(30)27-25(15-23(29)28-31)10-12-32-13-11-25/h2-9,14,31H,10-13,15-16H2,1H3,(H,27,30)(H,28,29) NUVSGXIVCJBRBF-UHFFFAOYSA-N 50183715 CHEMBL207305::N-(4-(2-(hydroxyamino)-2-oxoethyl)-tetrahydro-2H-pyran-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide::N-(4-(2-(hydroxyamino)-2-oxoethyl)tetrahydro-2H-pyran-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 150 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183715 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183715&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868333 104068149 CHEMBL207305 ZINC03817205 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339959 ONC(=O)C1(CNC(=O)c2ccc(OCc3ccnc4ccccc34)cc2)CCOCC1 InChI=1S/C24H25N3O5/c28-22(26-16-24(23(29)27-30)10-13-31-14-11-24)17-5-7-19(8-6-17)32-15-18-9-12-25-21-4-2-1-3-20(18)21/h1-9,12,30H,10-11,13-16H2,(H,26,28)(H,27,29) GVQWIKRRQMZNKU-UHFFFAOYSA-N 50183722 CHEMBL208052::N-hydroxy-4-((4-(quinolin-4-ylmethoxy)benzamido)methyl)-tetrahydro-2H-pyran-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183722 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183722&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44410935 104068156 CHEMBL208052 ZINC36351988 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339960 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(Cc3ccccc3)CC2)c2ccccc2n1 InChI=1S/C32H34N4O4/c1-23-19-26(28-9-5-6-10-29(28)33-23)22-40-27-13-11-25(12-14-27)31(38)34-32(20-30(37)35-39)15-17-36(18-16-32)21-24-7-3-2-4-8-24/h2-14,19,39H,15-18,20-22H2,1H3,(H,34,38)(H,35,37) PACKAWWLZSBYDP-UHFFFAOYSA-N 50183712 CHEMBL425415::N-(1-benzyl-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 290 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183712&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379210 104068146 CHEMBL425415 ZINC36351991 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339969 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC2)C(=O)CC(C)(C)C)c2ccccc2n1 InChI=1S/C31H38N4O5/c1-21-17-23(25-7-5-6-8-26(25)32-21)20-40-24-11-9-22(10-12-24)29(38)33-31(18-27(36)34-39)13-15-35(16-14-31)28(37)19-30(2,3)4/h5-12,17,39H,13-16,18-20H2,1-4H3,(H,33,38)(H,34,36) FQARNXJHFBTHOY-UHFFFAOYSA-N 50183724 CHEMBL207999::N-(1-(3,3-dimethylbutanoyl)-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 212 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183724&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10370226 104068158 CHEMBL207999 ZINC36351987 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339970 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC2)C(=O)OC(C)(C)C)c2ccccc2n1 InChI=1S/C30H36N4O6/c1-20-17-22(24-7-5-6-8-25(24)31-20)19-39-23-11-9-21(10-12-23)27(36)32-30(18-26(35)33-38)13-15-34(16-14-30)28(37)40-29(2,3)4/h5-12,17,38H,13-16,18-19H2,1-4H3,(H,32,36)(H,33,35) ISGKPJSIGMKCEK-UHFFFAOYSA-N 50183727 CHEMBL436950::tert-butyl 4-(2-(hydroxyamino)-2-oxoethyl)-4-(4-((2-methylquinolin-4-yl)methoxy)benzamido)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 370 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183727&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10209382 104068161 CHEMBL436950 ZINC03944019 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339976 Cc1cc(COc2ccc(cc2)C(=O)NCC2(CCN(CC2)C(=O)OC(C)(C)C)C(=O)NO)c2ccccc2n1 InChI=1S/C30H36N4O6/c1-20-17-22(24-7-5-6-8-25(24)32-20)18-39-23-11-9-21(10-12-23)26(35)31-19-30(27(36)33-38)13-15-34(16-14-30)28(37)40-29(2,3)4/h5-12,17,38H,13-16,18-19H2,1-4H3,(H,31,35)(H,33,36) UGXSRTBMCGSHRK-UHFFFAOYSA-N 50183718 CHEMBL208038::tert-butyl 4-(hydroxycarbamoyl)-4-((4-((2-methylquinolin-4-yl)methoxy)benzamido)methyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183718 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183718&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10230907 104068152 CHEMBL208038 ZINC36351981 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339981 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC2)S(C)(=O)=O)c2ccccc2n1 InChI=1S/C26H30N4O6S/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-36-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(14-12-26)37(2,34)35/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) DJBJEUJDVZJUDS-UHFFFAOYSA-N 50183725 CHEMBL206254::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-(methylsulfonyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 54 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183725 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183725&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10143028 104068159 CHEMBL206254 ZINC34315449 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339991 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC2)C2=NCCS2)c2ccccc2n1 InChI=1S/C28H31N5O4S/c1-19-16-21(23-4-2-3-5-24(23)30-19)18-37-22-8-6-20(7-9-22)26(35)31-28(17-25(34)32-36)10-13-33(14-11-28)27-29-12-15-38-27/h2-9,16,36H,10-15,17-18H2,1H3,(H,31,35)(H,32,34) XNQVZVNWVMQCPC-UHFFFAOYSA-N 50183732 CHEMBL205900::N-(1-(4,5-dihydrothiazol-2-yl)-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 30 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183732 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183732&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379254 104068166 CHEMBL205900 ZINC36351978 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339992 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC(C)(C)C)CC2)c2ccccc2n1 InChI=1S/C30H38N4O4/c1-21-17-23(25-7-5-6-8-26(25)31-21)19-38-24-11-9-22(10-12-24)28(36)32-30(18-27(35)33-37)13-15-34(16-14-30)20-29(2,3)4/h5-12,17,37H,13-16,18-20H2,1-4H3,(H,32,36)(H,33,35) MIUWEXKKKWGHOC-UHFFFAOYSA-N 50183729 CHEMBL207180::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-neopentylpiperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 143 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183729 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183729&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379123 104068163 CHEMBL207180 ZINC36351989 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339998 CCCN1CCC(CNC(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)(CC1)C(=O)NO InChI=1S/C28H34N4O4/c1-3-14-32-15-12-28(13-16-32,27(34)31-35)19-29-26(33)21-8-10-23(11-9-21)36-18-22-17-20(2)30-25-7-5-4-6-24(22)25/h4-11,17,35H,3,12-16,18-19H2,1-2H3,(H,29,33)(H,31,34) GTCRWKBEGBSXDD-UHFFFAOYSA-N 50183733 CHEMBL264119::N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)benzamido)methyl)-1-propylpiperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183733 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183733&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10278105 104068167 CHEMBL264119 ZINC36351976 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50339999 CN(C)C(=O)N1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C28H33N5O5/c1-19-16-21(23-6-4-5-7-24(23)29-19)18-38-22-10-8-20(9-11-22)26(35)30-28(17-25(34)31-37)12-14-33(15-13-28)27(36)32(2)3/h4-11,16,37H,12-15,17-18H2,1-3H3,(H,30,35)(H,31,34) ZTSCXJSYCOZWKZ-UHFFFAOYSA-N 50183734 4-(2-(hydroxyamino)-2-oxoethyl)-N,N-dimethyl-4-(4-((2-methylquinolin-4-yl)methoxy)benzamido)piperidine-1-carboxamide::CHEMBL207415 Disintegrin and metalloproteinase domain-containing protein 17 152 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183734&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10301584 104068168 CHEMBL207415 ZINC36351994 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340000 CN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C26H30N4O4/c1-18-15-20(22-5-3-4-6-23(22)27-18)17-34-21-9-7-19(8-10-21)25(32)28-26(16-24(31)29-33)11-13-30(2)14-12-26/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,28,32)(H,29,31) YVFLHFYMDLEMFY-UHFFFAOYSA-N 50183730 CHEMBL380895::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-methylpiperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 109 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183730 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183730&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10298369 104068164 CHEMBL380895 ZINC36351983 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340001 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC2)C(C)(C)C#C)c2ccccc2n1 InChI=1S/C30H34N4O4/c1-5-29(3,4)34-16-14-30(15-17-34,19-27(35)33-37)32-28(36)22-10-12-24(13-11-22)38-20-23-18-21(2)31-26-9-7-6-8-25(23)26/h1,6-13,18,37H,14-17,19-20H2,2-4H3,(H,32,36)(H,33,35) ALAICNBWAOLDPL-UHFFFAOYSA-N 50183731 CHEMBL207709::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-(2-methylbut-3-yn-2-yl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 490 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183731&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379077 104068165 CHEMBL207709 ZINC36351986 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340002 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCNCC2)c2ccccc2n1 InChI=1S/C25H28N4O4/c1-17-14-19(21-4-2-3-5-22(21)27-17)16-33-20-8-6-18(7-9-20)24(31)28-25(15-23(30)29-32)10-12-26-13-11-25/h2-9,14,26,32H,10-13,15-16H2,1H3,(H,28,31)(H,29,30) BODLESUVCQEUII-UHFFFAOYSA-N 50183711 CHEMBL208009::N-(4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 36 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183711 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183711&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10160968 104068145 CHEMBL208009 ZINC34355011 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340005 CCC(=O)N1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C28H32N4O5/c1-3-26(34)32-14-12-28(13-15-32,17-25(33)31-36)30-27(35)20-8-10-22(11-9-20)37-18-21-16-19(2)29-24-7-5-4-6-23(21)24/h4-11,16,36H,3,12-15,17-18H2,1-2H3,(H,30,35)(H,31,33) SFSKPKLATIXRLH-UHFFFAOYSA-N 50183716 CHEMBL381173::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-propionylpiperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 39 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183716 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183716&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10391428 104068150 CHEMBL381173 ZINC36351975 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340010 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCCCC2)c2ccccc2n1 InChI=1S/C26H29N3O4/c1-18-15-20(22-7-3-4-8-23(22)27-18)17-33-21-11-9-19(10-12-21)25(31)28-26(16-24(30)29-32)13-5-2-6-14-26/h3-4,7-12,15,32H,2,5-6,13-14,16-17H2,1H3,(H,28,31)(H,29,30) VRUYZVHIDJWWTM-UHFFFAOYSA-N 50183735 CHEMBL205290::N-(1-(2-(hydroxyamino)-2-oxoethyl)cyclohexyl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 737 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183735&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379149 104068169 CHEMBL205290 ZINC36351974 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340013 CC(C)C(=O)N1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C29H34N4O5/c1-19(2)28(36)33-14-12-29(13-15-33,17-26(34)32-37)31-27(35)21-8-10-23(11-9-21)38-18-22-16-20(3)30-25-7-5-4-6-24(22)25/h4-11,16,19,37H,12-15,17-18H2,1-3H3,(H,31,35)(H,32,34) CBKSKDVWCOUHEC-UHFFFAOYSA-N 50183723 CHEMBL207726::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-isobutyrylpiperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 89 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183723 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183723&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379235 104068157 CHEMBL207726 ZINC36351980 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340014 CC(=O)N1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C27H30N4O5/c1-18-15-21(23-5-3-4-6-24(23)28-18)17-36-22-9-7-20(8-10-22)26(34)29-27(16-25(33)30-35)11-13-31(14-12-27)19(2)32/h3-10,15,35H,11-14,16-17H2,1-2H3,(H,29,34)(H,30,33) QRWVORUSUQDRRN-UHFFFAOYSA-N 50183721 CHEMBL381953::N-(1-acetyl-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183721&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10300063 104068155 CHEMBL381953 ZINC36351996 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340019 CCCN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C28H34N4O4/c1-3-14-32-15-12-28(13-16-32,18-26(33)31-35)30-27(34)21-8-10-23(11-9-21)36-19-22-17-20(2)29-25-7-5-4-6-24(22)25/h4-11,17,35H,3,12-16,18-19H2,1-2H3,(H,30,34)(H,31,33) ADROOOBIKREWPX-UHFFFAOYSA-N 50183719 CHEMBL208022::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-propylpiperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 96 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183719 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183719&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10300077 104068153 CHEMBL208022 ZINC36351984 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340023 CCS(=O)(=O)CCN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C29H36N4O6S/c1-3-40(37,38)17-16-33-14-12-29(13-15-33,19-27(34)32-36)31-28(35)22-8-10-24(11-9-22)39-20-23-18-21(2)30-26-7-5-4-6-25(23)26/h4-11,18,36H,3,12-17,19-20H2,1-2H3,(H,31,35)(H,32,34) CTANAKVMPKAIQD-UHFFFAOYSA-N 50183713 CHEMBL208172::N-(1-(2-(ethylsulfonyl)ethyl)-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 119 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183713 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183713&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379040 104068147 CHEMBL208172 ZINC36351985 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340032 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC2)C(C)(C)C)c2ccccc2n1 InChI=1S/C29H36N4O4/c1-20-17-22(24-7-5-6-8-25(24)30-20)19-37-23-11-9-21(10-12-23)27(35)31-29(18-26(34)32-36)13-15-33(16-14-29)28(2,3)4/h5-12,17,36H,13-16,18-19H2,1-4H3,(H,31,35)(H,32,34) HBYOIHRPSQTDLO-UHFFFAOYSA-N 50183737 CHEMBL205523::N-(1-tert-butyl-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 56 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183737&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379187 104068171 CHEMBL205523 ZINC36351977 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340058 CCN1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C27H32N4O4/c1-3-31-14-12-27(13-15-31,17-25(32)30-34)29-26(33)20-8-10-22(11-9-20)35-18-21-16-19(2)28-24-7-5-4-6-23(21)24/h4-11,16,34H,3,12-15,17-18H2,1-2H3,(H,29,33)(H,30,32) RBUVXLALMRWKQA-UHFFFAOYSA-N 50183726 CHEMBL207468::N-(1-ethyl-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183726 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183726&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10140438 104068160 CHEMBL207468 ZINC34312332 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340060 Cc1cc(COc2ccc(cc2)C(=O)NCC2(CCN(CC2)S(C)(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C26H30N4O6S/c1-18-15-20(22-5-3-4-6-23(22)28-18)16-36-21-9-7-19(8-10-21)24(31)27-17-26(25(32)29-33)11-13-30(14-12-26)37(2,34)35/h3-10,15,33H,11-14,16-17H2,1-2H3,(H,27,31)(H,29,32) WIFSQEZIILGJQU-UHFFFAOYSA-N 50183739 CHEMBL208051::N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)benzamido)methyl)-1-(methylsulfonyl)piperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183739&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10143029 104068173 CHEMBL208051 ZINC34315450 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340066 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CCF)CC2)c2ccccc2n1 InChI=1S/C27H31FN4O4/c1-19-16-21(23-4-2-3-5-24(23)29-19)18-36-22-8-6-20(7-9-22)26(34)30-27(17-25(33)31-35)10-13-32(14-11-27)15-12-28/h2-9,16,35H,10-15,17-18H2,1H3,(H,30,34)(H,31,33) MCNQDQIVWJTIBW-UHFFFAOYSA-N 50183736 CHEMBL207018::N-(1-(2-fluoroethyl)-4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 90 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183736&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10185100 104068170 CHEMBL207018 ZINC34802364 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340071 Cc1cc(COc2ccc(cc2)C(=O)NCC2(CCNCC2)C(=O)NO)c2ccccc2n1 InChI=1S/C25H28N4O4/c1-17-14-19(21-4-2-3-5-22(21)28-17)15-33-20-8-6-18(7-9-20)23(30)27-16-25(24(31)29-32)10-12-26-13-11-25/h2-9,14,26,32H,10-13,15-16H2,1H3,(H,27,30)(H,29,31) SKOOTXQZWQKIPT-UHFFFAOYSA-N 50183738 CHEMBL208039::N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)benzamido)methyl)piperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183738 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183738&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10225737 104068172 CHEMBL208039 ZINC36351982 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340073 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CCS(C)(=O)=O)CC2)c2ccccc2n1 InChI=1S/C28H34N4O6S/c1-20-17-22(24-5-3-4-6-25(24)29-20)19-38-23-9-7-21(8-10-23)27(34)30-28(18-26(33)31-35)11-13-32(14-12-28)15-16-39(2,36)37/h3-10,17,35H,11-16,18-19H2,1-2H3,(H,30,34)(H,31,33) MJYOLQLJRBLLML-UHFFFAOYSA-N 50183717 CHEMBL382352::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-(2-(methylsulfonyl)ethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 45 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183717 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183717&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379115 104068151 CHEMBL382352 ZINC36351979 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340098 Cc1cc(COc2ccc(cc2)C(=O)NCC2(CCCCC2)C(=O)NO)c2ccccc2n1 InChI=1S/C26H29N3O4/c1-18-15-20(22-7-3-4-8-23(22)28-18)16-33-21-11-9-19(10-12-21)24(30)27-17-26(25(31)29-32)13-5-2-6-14-26/h3-4,7-12,15,32H,2,5-6,13-14,16-17H2,1H3,(H,27,30)(H,29,31) VWGRXRDSZRYUEN-UHFFFAOYSA-N 50183740 CHEMBL206930::N-((1-(hydroxycarbamoyl)cyclohexyl)methyl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183740&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379087 104068174 CHEMBL206930 ZINC36351995 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340101 Cc1cc(COc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCN(CC2)C(=O)C(C)(C)C)c2ccccc2n1 InChI=1S/C30H36N4O5/c1-20-17-22(24-7-5-6-8-25(24)31-20)19-39-23-11-9-21(10-12-23)27(36)32-30(18-26(35)33-38)13-15-34(16-14-30)28(37)29(2,3)4/h5-12,17,38H,13-16,18-19H2,1-4H3,(H,32,36)(H,33,35) OVSGONSKJHXDJO-UHFFFAOYSA-N 50183714 CHEMBL206993::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-pivaloylpiperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 102 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183714 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183714&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10302088 104068148 CHEMBL206993 ZINC36351992 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340113 Cc1cc(COc2ccc(cc2)C(=O)NCC2(CCN(CC2)C(=O)C(C)(C)C)C(=O)NO)c2ccccc2n1 InChI=1S/C30H36N4O5/c1-20-17-22(24-7-5-6-8-25(24)32-20)18-39-23-11-9-21(10-12-23)26(35)31-19-30(27(36)33-38)13-15-34(16-14-30)28(37)29(2,3)4/h5-12,17,38H,13-16,18-19H2,1-4H3,(H,31,35)(H,33,36) ZVSJOTVLDZPITK-UHFFFAOYSA-N 50183741 CHEMBL204627::N-hydroxy-4-((4-((2-methylquinolin-4-yl)methoxy)benzamido)methyl)-1-pivaloylpiperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183741&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10165477 104068175 CHEMBL204627 ZINC34366584 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340114 CC(C)CC(=O)N1CCC(CC(=O)NO)(CC1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1 InChI=1S/C30H36N4O5/c1-20(2)16-28(36)34-14-12-30(13-15-34,18-27(35)33-38)32-29(37)22-8-10-24(11-9-22)39-19-23-17-21(3)31-26-7-5-4-6-25(23)26/h4-11,17,20,38H,12-16,18-19H2,1-3H3,(H,32,37)(H,33,35) NHMWZOLCOOIQJX-UHFFFAOYSA-N 50183720 CHEMBL207683::N-(4-(2-(hydroxyamino)-2-oxoethyl)-1-(3-methylbutanoyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 105 ChEMBL 10.1016/j.bmcl.2006.02.015 10.7270/Q2TB16H3 16516466 Gilmore, JL; King, BW; Harris, C; Maduskuie, T; Mercer, SE; Liu, RQ; Covington, MB; Qian, M; Ribadeneria, MD; Vaddi, K; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183720 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183720&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18379435 104068154 CHEMBL207683 ZINC36351993 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340156 COc1ccc(cc1)[C@H]([C@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)C(=O)N1CCCCC1 InChI=1S/C23H32N4O6/c1-23(2)21(30)27(22(31)25(23)3)14-17(19(28)24-32)18(15-8-10-16(33-4)11-9-15)20(29)26-12-6-5-7-13-26/h8-11,17-18,32H,5-7,12-14H2,1-4H3,(H,24,28)/t17-,18+/m0/s1 MHYRZRJQEBSULL-ZWKOTPCHSA-N 50183782 (2R,3S)-N-hydroxy-3-(4-methoxyphenyl)-4-oxo-4-(piperidin-1-yl)-2-((3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl)butanamide::CHEMBL438964 Disintegrin and metalloproteinase domain-containing protein 17 321 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183782&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44411053 104068213 CHEMBL438964 ZINC34801777 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340167 CNC(=O)[C@@H](NC(=O)[C@@H]([C@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)c1ccc(OC)cc1)C(C)(C)C InChI=1S/C25H37N5O7/c1-24(2,3)18(21(33)26-6)27-20(32)17(14-9-11-15(37-8)12-10-14)16(19(31)28-36)13-30-22(34)25(4,5)29(7)23(30)35/h9-12,16-18,36H,13H2,1-8H3,(H,26,33)(H,27,32)(H,28,31)/t16-,17+,18+/m0/s1 MWYSQPGMUZLIHV-RCCFBDPRSA-N 50183783 (2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-(4-methoxyphenyl)-3-((3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl)succinamide::CHEMBL208181 Disintegrin and metalloproteinase domain-containing protein 17 57 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183783&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44411052 104068214 CHEMBL208181 ZINC34801776 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340174 CNC(=O)[C@@H](NC(=O)[C@@H]([C@H](CO)C(=O)NO)c1ccc(OC)cc1)C(C)(C)C InChI=1S/C19H29N3O6/c1-19(2,3)15(18(26)20-4)21-17(25)14(13(10-23)16(24)22-27)11-6-8-12(28-5)9-7-11/h6-9,13-15,23,27H,10H2,1-5H3,(H,20,26)(H,21,25)(H,22,24)/t13-,14+,15+/m0/s1 IOLRUMINDIUCLJ-RRFJBIMHSA-N 50183784 (2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-3-(hydroxymethyl)-2-(4-methoxyphenyl)succinamide::(2S,3R)-N4-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N1-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide::CHEMBL72511::N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide::PKF-242-484::TNF-484 Disintegrin and metalloproteinase domain-containing protein 17 0.6 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183784&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9886977 104068215 CHEMBL72511 ZINC13473801 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340176 CNC(=O)[C@@H]1CCCCN1C(=O)[C@@H]([C@H](CO)C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H27N3O6/c1-20-18(25)15-5-3-4-10-22(15)19(26)16(14(11-23)17(24)21-27)12-6-8-13(28-2)9-7-12/h6-9,14-16,23,27H,3-5,10-11H2,1-2H3,(H,20,25)(H,21,24)/t14-,15-,16+/m0/s1 COUUBDFXGTZTPW-HRCADAONSA-N 50183787 (S)-1-((2S,3R)-4-(hydroxyamino)-3-(hydroxymethyl)-2-(4-methoxyphenyl)-4-oxobutanoyl)-N-methylpiperidine-2-carboxamide::CHEMBL439330 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183787&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10237550 104068218 CHEMBL439330 ZINC34801932 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340178 CC[C@@H]([C@H](C(=O)N1CCCC[C@H]1C(=O)NC)c1ccc(Cl)cc1)C(=O)NO InChI=1S/C19H26ClN3O4/c1-3-14(17(24)22-27)16(12-7-9-13(20)10-8-12)19(26)23-11-5-4-6-15(23)18(25)21-2/h7-10,14-16,27H,3-6,11H2,1-2H3,(H,21,25)(H,22,24)/t14-,15-,16+/m0/s1 NRCQPJPKKZDRND-HRCADAONSA-N 50183781 (S)-1-((2S,3S)-2-(4-chlorophenyl)-3-(hydroxycarbamoyl)pentanoyl)-N-methylpiperidine-2-carboxamide::CHEMBL382705 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183781&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11603611 104068212 CHEMBL382705 ZINC34801778 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340180 CN1C(=O)N(C[C@@H]([C@@H](CC2CCCC2)C(=O)N2CCCCC2)C(=O)NO)C(=O)C1(C)C InChI=1S/C22H36N4O5/c1-22(2)20(29)26(21(30)24(22)3)14-17(18(27)23-31)16(13-15-9-5-6-10-15)19(28)25-11-7-4-8-12-25/h15-17,31H,4-14H2,1-3H3,(H,23,27)/t16-,17+/m1/s1 GFUITADOEPNRML-SJORKVTESA-N 30344 Cipemastat::Trocade Disintegrin and metalloproteinase domain-containing protein 17 230 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30344&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9824350 85148104 6466 ZINC00600699 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340182 COc1ccc(cc1)[C@H]([C@H](CO)C(=O)NO)C(=O)N1CCCCC1 InChI=1S/C17H24N2O5/c1-24-13-7-5-12(6-8-13)15(14(11-20)16(21)18-23)17(22)19-9-3-2-4-10-19/h5-8,14-15,20,23H,2-4,9-11H2,1H3,(H,18,21)/t14-,15+/m0/s1 ZFXFRRPQPVEFAM-LSDHHAIUSA-N 50183786 (2R,3S)-N-hydroxy-2-(hydroxymethyl)-3-(4-methoxyphenyl)-4-oxo-4-(piperidin-1-yl)butanamide::CHEMBL206875 Disintegrin and metalloproteinase domain-containing protein 17 66 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183786&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10125869 104068217 CHEMBL206875 ZINC34269595 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50340183 CC[C@@H]([C@H](C(=O)N1CCCC[C@H]1C(=O)NC)c1ccc(OC)cc1)C(=O)NO InChI=1S/C20H29N3O5/c1-4-15(18(24)22-27)17(13-8-10-14(28-3)11-9-13)20(26)23-12-6-5-7-16(23)19(25)21-2/h8-11,15-17,27H,4-7,12H2,1-3H3,(H,21,25)(H,22,24)/t15-,16-,17+/m0/s1 ZQORGANDVNQVJF-YESZJQIVSA-N 50183785 (S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyphenyl)pentanoyl)-N-methylpiperidine-2-carboxamide::CHEMBL207756 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183785&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10150649 104068216 CHEMBL207756 ZINC34323223 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335269 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@H](CNS(C)(=O)=O)SC(C)(C)[C@@H]1C(=O)NO InChI=1S/C19H27N3O7S3/c1-5-6-11-29-14-7-9-16(10-8-14)32(27,28)22-13-15(12-20-31(4,25)26)30-19(2,3)17(22)18(23)21-24/h7-10,15,17,20,24H,11-13H2,1-4H3,(H,21,23)/t15-,17-/m0/s1 NUDMVYOFBGJGMN-RDJZCZTQSA-N 50180994 (3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethyl-6-(methylsulfonamidomethyl)thiomorpholine-3-carboxamide::CHEMBL206481 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180994&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409389 104065853 CHEMBL206481 ZINC28572159 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335272 CC(C)(C)OC(=O)NCCCCC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C25H37N3O7S2/c1-24(2,3)35-23(30)26-15-9-7-6-8-10-17-34-19-11-13-20(14-12-19)37(32,33)28-16-18-36-25(4,5)21(28)22(29)27-31/h11-14,21,31H,6-7,9,15-18H2,1-5H3,(H,26,30)(H,27,29)/t21-/m0/s1 NGEXELWTFRTJEQ-NRFANRHFSA-N 50180997 (S)-tert-butyl 7-(4-(3-(hydroxycarbamoyl)-2,2-dimethylthiomorpholinosulfonyl)phenoxy)hept-5-ynylcarbamate::CHEMBL381505 Disintegrin and metalloproteinase domain-containing protein 17 199 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180997&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409164 104065856 CHEMBL381505 ZINC28571939 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335276 CC(C)(C)OC(=O)NCCC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C23H33N3O7S2/c1-22(2,3)33-21(28)24-13-7-6-8-15-32-17-9-11-18(12-10-17)35(30,31)26-14-16-34-23(4,5)19(26)20(27)25-29/h9-12,19,29H,7,13-16H2,1-5H3,(H,24,28)(H,25,27)/t19-/m0/s1 HKAXLEJIOVCYCD-IBGZPJMESA-N 50181001 (S)-tert-butyl 5-(4-(3-(hydroxycarbamoyl)-2,2-dimethylthiomorpholinosulfonyl)phenoxy)pent-3-ynylcarbamate::CHEMBL380343 Disintegrin and metalloproteinase domain-containing protein 17 112 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181001&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409197 104065860 CHEMBL380343 ZINC28571055 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335277 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#C)cc1 InChI=1S/C16H20N2O5S2/c1-4-10-23-12-5-7-13(8-6-12)25(21,22)18-9-11-24-16(2,3)14(18)15(19)17-20/h1,5-8,14,20H,9-11H2,2-3H3,(H,17,19)/t14-/m0/s1 KLSLMSQYLRDFGN-AWEZNQCLSA-N 50181002 (S)-N-hydroxy-2,2-dimethyl-4-(4-(prop-2-ynyloxy)phenylsulfonyl)thiomorpholine-3-carboxamide::CHEMBL207776 Disintegrin and metalloproteinase domain-containing protein 17 19 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181002&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21304710 104065861 CHEMBL207776 ZINC34801930 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335284 CCCCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C17H26N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,4-5,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1 SHTYCRVVDNRZDY-HNNXBMFYSA-N 50181003 (S)-4-(4-butoxyphenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL380439 Disintegrin and metalloproteinase domain-containing protein 17 42 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181003&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409221 104065862 CHEMBL380439 ZINC28571525 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335286 CC(C)(C)OC(=O)NCCCC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C24H35N3O7S2/c1-23(2,3)34-22(29)25-14-8-6-7-9-16-33-18-10-12-19(13-11-18)36(31,32)27-15-17-35-24(4,5)20(27)21(28)26-30/h10-13,20,30H,6,8,14-17H2,1-5H3,(H,25,29)(H,26,28)/t20-/m0/s1 TZYCKWCFYXFTIR-FQEVSTJZSA-N 50181007 (S)-tert-butyl 6-(4-(3-(hydroxycarbamoyl)-2,2-dimethylthiomorpholinosulfonyl)phenoxy)hex-4-ynylcarbamate::CHEMBL206155 Disintegrin and metalloproteinase domain-containing protein 17 153 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181007&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409163 104065866 CHEMBL206155 ZINC28571938 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335289 CCN(CC)CC[C@H]1CN([C@@H](C(=O)NO)C(C)(C)S1)S(=O)(=O)c1ccc(OCC#CC)cc1 InChI=1S/C23H35N3O5S2/c1-6-9-16-31-18-10-12-20(13-11-18)33(29,30)26-17-19(14-15-25(7-2)8-3)32-23(4,5)21(26)22(27)24-28/h10-13,19,21,28H,7-8,14-17H2,1-5H3,(H,24,27)/t19-,21-/m0/s1 BUSXTPHZLBAFDD-FPOVZHCZSA-N 50181009 (3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-6-(2-(diethylamino)ethyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL205998 Disintegrin and metalloproteinase domain-containing protein 17 143 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181009&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409405 104065868 CHEMBL205998 ZINC34801931 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335294 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCCCC#C)cc1 InChI=1S/C18H24N2O5S2/c1-4-5-6-12-25-14-7-9-15(10-8-14)27(23,24)20-11-13-26-18(2,3)16(20)17(21)19-22/h1,7-10,16,22H,5-6,11-13H2,2-3H3,(H,19,21)/t16-/m0/s1 LWZOHIDILGLXGF-INIZCTEOSA-N 50181012 (S)-N-hydroxy-2,2-dimethyl-4-(4-(pent-4-ynyloxy)phenylsulfonyl)thiomorpholine-3-carboxamide::CHEMBL441177 Disintegrin and metalloproteinase domain-containing protein 17 40 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181012&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409214 104065871 CHEMBL441177 ZINC28571658 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335295 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCCC#C)cc1 InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h1,6-9,15,21H,5,10-12H2,2-3H3,(H,18,20)/t15-/m0/s1 ZWHGUGYVAMXPJZ-HNNXBMFYSA-N 50181006 (S)-4-(4-(but-3-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206688 Disintegrin and metalloproteinase domain-containing protein 17 32 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181006&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409261 104065865 CHEMBL206688 ZINC28572463 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335304 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@H](CC(O)=O)SC(C)(C)[C@@H]1C(=O)NO InChI=1S/C19H24N2O7S2/c1-4-5-10-28-13-6-8-15(9-7-13)30(26,27)21-12-14(11-16(22)23)29-19(2,3)17(21)18(24)20-25/h6-9,14,17,25H,10-12H2,1-3H3,(H,20,24)(H,22,23)/t14-,17-/m0/s1 VDJRMQXPNKTLQA-YOEHRIQHSA-N 50181013 2-((2S,5S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-5-(hydroxycarbamoyl)-6,6-dimethylthiomorpholin-2-yl)acetic acid::CHEMBL381163 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181013&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409365 104065872 CHEMBL381163 ZINC28572481 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335306 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCCCCO)cc1 InChI=1S/C20H28N2O6S2/c1-20(2)18(19(24)21-25)22(12-15-29-20)30(26,27)17-10-8-16(9-11-17)28-14-7-5-3-4-6-13-23/h8-11,18,23,25H,3-4,6,12-15H2,1-2H3,(H,21,24)/t18-/m0/s1 ZWHIVWLHYJCFFA-SFHVURJKSA-N 50181000 (S)-N-hydroxy-4-(4-(7-hydroxyhept-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL382585 Disintegrin and metalloproteinase domain-containing protein 17 53 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181000&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409047 104065859 CHEMBL382585 ZINC28571033 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335309 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCCCO)cc1 InChI=1S/C19H26N2O6S2/c1-19(2)17(18(23)20-24)21(11-14-28-19)29(25,26)16-9-7-15(8-10-16)27-13-6-4-3-5-12-22/h7-10,17,22,24H,3,5,11-14H2,1-2H3,(H,20,23)/t17-/m0/s1 GHZXWVPNZMUKBT-KRWDZBQOSA-N 50181015 (S)-N-hydroxy-4-(4-(6-hydroxyhex-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206144 Disintegrin and metalloproteinase domain-containing protein 17 40 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181015&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409042 104065874 CHEMBL206144 ZINC28571178 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335312 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1 CVZIHNYAZLXRRS-HNNXBMFYSA-N 23498 (3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL207729::TMI-1 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23498&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search IH6 1ZXC 5288615 50091760 CHEMBL207729 DB07964 ZINC03817227 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335313 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCCCN)cc1 InChI=1S/C19H27N3O5S2/c1-19(2)17(18(23)21-24)22(12-14-28-19)29(25,26)16-9-7-15(8-10-16)27-13-6-4-3-5-11-20/h7-10,17,24H,3,5,11-14,20H2,1-2H3,(H,21,23)/t17-/m0/s1 YTTGWCXMRQNZJI-KRWDZBQOSA-N 50181017 (S)-4-(4-(6-aminohex-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL383028 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181017&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21304705 104065876 CHEMBL383028 ZINC28572059 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335314 C\C=C\COc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C17H24N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h4-9,15,21H,10-12H2,1-3H3,(H,18,20)/b5-4+/t15-/m0/s1 ZYZUZMRFPDIWGW-RGDDUWESSA-N 50180999 (S,E)-4-(4-(but-2-enyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL383079 Disintegrin and metalloproteinase domain-containing protein 17 35 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180999&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409215 104065858 CHEMBL383079 ZINC28571659 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335322 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCCN)cc1 InChI=1S/C18H25N3O5S2/c1-18(2)16(17(22)20-23)21(11-13-27-18)28(24,25)15-8-6-14(7-9-15)26-12-5-3-4-10-19/h6-9,16,23H,4,10-13,19H2,1-2H3,(H,20,22)/t16-/m0/s1 DOPZAFIJEYWGQT-INIZCTEOSA-N 50180996 (S)-4-(4-(5-aminopent-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL202899 Disintegrin and metalloproteinase domain-containing protein 17 138 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180996&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409184 104065855 CHEMBL202899 ZINC28571035 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335323 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCCO)cc1 InChI=1S/C18H24N2O6S2/c1-18(2)16(17(22)19-23)20(10-13-27-18)28(24,25)15-8-6-14(7-9-15)26-12-5-3-4-11-21/h6-9,16,21,23H,4,10-13H2,1-2H3,(H,19,22)/t16-/m0/s1 MLHIPHSANXGLHI-INIZCTEOSA-N 50181014 (S)-N-hydroxy-4-(4-(5-hydroxypent-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL202806 Disintegrin and metalloproteinase domain-containing protein 17 62 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181014&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409041 104065873 CHEMBL202806 ZINC28571107 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335324 CCCCC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C20H28N2O5S2/c1-4-5-6-7-8-14-27-16-9-11-17(12-10-16)29(25,26)22-13-15-28-20(2,3)18(22)19(23)21-24/h9-12,18,24H,4-6,13-15H2,1-3H3,(H,21,23)/t18-/m0/s1 ZMAYDSCNOCAOHA-SFHVURJKSA-N 50181005 (S)-4-(4-(hept-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206298 Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181005&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409222 104065864 CHEMBL206298 ZINC28571526 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335325 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CC#C)cc1 InChI=1S/C18H20N2O5S2/c1-4-5-6-12-25-14-7-9-15(10-8-14)27(23,24)20-11-13-26-18(2,3)16(20)17(21)19-22/h1,7-10,16,22H,11-13H2,2-3H3,(H,19,21)/t16-/m0/s1 IXEFVZDHNHSUSD-INIZCTEOSA-N 50181004 (S)-N-hydroxy-2,2-dimethyl-4-(4-(penta-2,4-diynyloxy)phenylsulfonyl)thiomorpholine-3-carboxamide::CHEMBL440945 Disintegrin and metalloproteinase domain-containing protein 17 42 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181004&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21304708 104065863 CHEMBL440945 ZINC28572427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335327 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@H](CN)SC(C)(C)[C@@H]1C(=O)NO InChI=1S/C18H25N3O5S2/c1-4-5-10-26-13-6-8-15(9-7-13)28(24,25)21-12-14(11-19)27-18(2,3)16(21)17(22)20-23/h6-9,14,16,23H,10-12,19H2,1-3H3,(H,20,22)/t14-,16-/m0/s1 XNLVNQQMTWGGIM-HOCLYGCPSA-N 50181010 (3S,6S)-6-(aminomethyl)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL204100 Disintegrin and metalloproteinase domain-containing protein 17 57 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181010&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409369 104065869 CHEMBL204100 ZINC03817228 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335328 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@H](CC(N)=O)SC(C)(C)[C@@H]1C(=O)NO InChI=1S/C19H25N3O6S2/c1-4-5-10-28-13-6-8-15(9-7-13)30(26,27)22-12-14(11-16(20)23)29-19(2,3)17(22)18(24)21-25/h6-9,14,17,25H,10-12H2,1-3H3,(H2,20,23)(H,21,24)/t14-,17-/m0/s1 AVQCFDJVRXAPJO-YOEHRIQHSA-N 50181011 (3S,6S)-6-(2-amino-2-oxoethyl)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206739 Disintegrin and metalloproteinase domain-containing protein 17 42 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181011&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409366 104065870 CHEMBL206739 ZINC28572482 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335332 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCCCCN)cc1 InChI=1S/C20H29N3O5S2/c1-20(2)18(19(24)22-25)23(13-15-29-20)30(26,27)17-10-8-16(9-11-17)28-14-7-5-3-4-6-12-21/h8-11,18,25H,3-4,6,12-15,21H2,1-2H3,(H,22,24)/t18-/m0/s1 LHUIUEQQDGBKCU-SFHVURJKSA-N 50181016 (S)-4-(4-(7-aminohept-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL203886 Disintegrin and metalloproteinase domain-containing protein 17 40 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181016&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21304706 104065875 CHEMBL203886 ZINC28571253 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335333 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCN)cc1 InChI=1S/C17H23N3O5S2/c1-17(2)15(16(21)19-22)20(10-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-9-18/h5-8,15,22H,9-12,18H2,1-2H3,(H,19,21)/t15-/m0/s1 AANXPIMDONQTQF-HNNXBMFYSA-N 50180995 (S)-4-(4-(4-aminobut-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::4-({4-[(4-AMINOBUT-2-YNYL)OXY]PHENYL}SULFONYL)-N-HYDROXY-2,2-DIMETHYLTHIOMORPHOLINE-3-CARBOXAMIDE::CHEMBL202839 Disintegrin and metalloproteinase domain-containing protein 17 67 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180995&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 4NH 2A8H 6102708 104065854 CHEMBL202839 DB07121 ZINC16051763 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335338 CC(C)(C)OC(=O)NCC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C22H31N3O7S2/c1-21(2,3)32-20(27)23-12-6-7-14-31-16-8-10-17(11-9-16)34(29,30)25-13-15-33-22(4,5)18(25)19(26)24-28/h8-11,18,28H,12-15H2,1-5H3,(H,23,27)(H,24,26)/t18-/m0/s1 GTOFARSZXYDPTC-SFHVURJKSA-N 50181018 (S)-tert-butyl 4-(4-(3-(hydroxycarbamoyl)-2,2-dimethylthiomorpholinosulfonyl)phenoxy)but-2-ynylcarbamate::CHEMBL437499 Disintegrin and metalloproteinase domain-containing protein 17 74 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181018&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409066 104065877 CHEMBL437499 ZINC28571790 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335339 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1 InChI=1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21)/t15-/m0/s1 MAVDNGWEBZTACC-HNNXBMFYSA-N 50181008 (S)-N-hydroxy-4-(4-(4-hydroxybut-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206815::TMI-05::US9266848, Apratastat::US9365529, Apratastat Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181008&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11452716 104065867 CHEMBL206815 6482 ZINC28571311 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335346 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1 InChI=1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21)/t15-/m0/s1 MAVDNGWEBZTACC-HNNXBMFYSA-N 50181008 (S)-N-hydroxy-4-(4-(4-hydroxybut-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206815::TMI-05::US9266848, Apratastat::US9365529, Apratastat Disintegrin and metalloproteinase domain-containing protein 17 300000 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181008&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11452716 104065867 CHEMBL206815 6482 ZINC28571311 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50335347 CC#CCOc1ccc(cc1)S(=O)(=O)N1C[C@H](CCO)SC(C)(C)[C@@H]1C(=O)NO InChI=1S/C19H26N2O6S2/c1-4-5-12-27-14-6-8-16(9-7-14)29(25,26)21-13-15(10-11-22)28-19(2,3)17(21)18(23)20-24/h6-9,15,17,22,24H,10-13H2,1-3H3,(H,20,23)/t15-,17-/m0/s1 MGQZHWBYKGXMDX-RDJZCZTQSA-N 50180998 (3S,6S)-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-6-(2-hydroxyethyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL381554 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/j.bmcl.2005.12.020 10.7270/Q2GF0T3Q 16426848 Levin, JI; Chen, JM; Laakso, LM; Du, M; Schmid, J; Xu, W; Cummons, T; Xu, J; Jin, G; Barone, D; Skotnicki, JS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50180998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50180998&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44409390 104065857 CHEMBL381554 ZINC28572160 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50337811 CCC[C@@H]([C@@H](CC(C)C)C(=O)N[C@H]1CCCCN(Cc2cccc(Oc3ccccc3)c2)C1=O)C(=O)NO InChI=1S/C30H41N3O5/c1-4-11-25(29(35)32-37)26(18-21(2)3)28(34)31-27-16-8-9-17-33(30(27)36)20-22-12-10-15-24(19-22)38-23-13-6-5-7-14-23/h5-7,10,12-15,19,21,25-27,37H,4,8-9,11,16-18,20H2,1-3H3,(H,31,34)(H,32,35)/t25-,26+,27-/m0/s1 WICQDDCNCVTFDX-VJGNERBWSA-N 50182403 (2R,3S)-N1-((S)-1-(3-phenoxybenzyl)-2-oxoazepan-3-yl)-N4-hydroxy-2-isobutyl-3-propylsuccinamide::(2S,3R)-N1-hydroxy-3-isobutyl-N4-((S)-2-oxo-1-(3-phenoxybenzyl)azepan-3-yl)-2-propylsuccinamide::CHEMBL204357::SR-973 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2006.01.055 10.7270/Q2WD405K 16473009 Thompson, LA; Liauw, AY; Ramanjulu, MM; Kasireddy-Polam, P; Mercer, SE; Maduskuie, TP; Glicksman, M; Roach, AH; Meredith, JE; Liu, RQ; Combs, AP; Higaki, JN; Cordell, B; Seiffert, D; Zaczek, RC; Robertson, DW; Olson, RE Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50182403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50182403&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9849669 104067137 CHEMBL204357 ZINC34801833 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347445 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H28N2O7S2/c1-4-5-14-29-17-6-8-18(9-7-17)30(25,26)15-20(19(23)21-24)10-12-22(13-11-20)31(27,28)16(2)3/h6-9,16,24H,10-15H2,1-3H3,(H,21,23) CEVLUPQNDFOYSI-UHFFFAOYSA-N 23500 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::CHEMBL209970::beta-sulfonyl hydroxamate analogue, 4 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23500&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11634234 50091761 CHEMBL209970 ZINC06718474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347449 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)CCCN(C)C)C(=O)NO InChI=1S/C23H33N3O6S/c1-4-5-17-32-19-8-10-20(11-9-19)33(30,31)18-23(22(28)24-29)12-15-26(16-13-23)21(27)7-6-14-25(2)3/h8-11,29H,6-7,12-18H2,1-3H3,(H,24,28) KSOLTKWEALJMDR-UHFFFAOYSA-N 50187785 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(dimethylamino)butanoyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL425783 Disintegrin and metalloproteinase domain-containing protein 17 4.9 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187785&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44414029 104071611 CHEMBL425783 ZINC34801895 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347451 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC#CC)CC1)C(=O)NO InChI=1S/C21H26N2O5S/c1-3-5-13-23-14-11-21(12-15-23,20(24)22-25)17-29(26,27)19-9-7-18(8-10-19)28-16-6-4-2/h7-10,25H,11-17H2,1-2H3,(H,22,24) YLPGDDBCDVVMDA-UHFFFAOYSA-N 50187787 1-(but-2-ynyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL209490 Disintegrin and metalloproteinase domain-containing protein 17 4.8 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187787&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513845 104071613 CHEMBL209490 ZINC34801901 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347453 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)C(C)(CO)CO)C(=O)NO InChI=1S/C22H30N2O8S/c1-3-4-13-32-17-5-7-18(8-6-17)33(30,31)16-22(19(27)23-29)9-11-24(12-10-22)20(28)21(2,14-25)15-26/h5-8,25-26,29H,9-16H2,1-2H3,(H,23,27) NILIMKWDWHKQOZ-UHFFFAOYSA-N 50187788 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(3-hydroxy-2-(hydroxymethyl)-2-methylpropanoyl)piperidine-4-carboxamide::CHEMBL211274 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187788 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187788&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513831 104071614 CHEMBL211274 ZINC03924194 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347469 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCNCC1)C(=O)NO InChI=1S/C17H22N2O5S/c1-2-3-12-24-14-4-6-15(7-5-14)25(22,23)13-17(16(20)19-21)8-10-18-11-9-17/h4-7,18,21H,8-13H2,1H3,(H,19,20) HTEPICDCVMJOSJ-UHFFFAOYSA-N 30136 CHEMBL385821::beta-sulfone piperidine hydroxamate, 2a Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30136&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44143475 85147897 CHEMBL385821 ZINC34802398 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347477 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(Cc2ccncc2)CC1)C(=O)NO InChI=1S/C23H27N3O5S/c1-2-3-16-31-20-4-6-21(7-5-20)32(29,30)18-23(22(27)25-28)10-14-26(15-11-23)17-19-8-12-24-13-9-19/h4-9,12-13,28H,10-11,14-18H2,1H3,(H,25,27) XIQNNSMTTLQUTR-UHFFFAOYSA-N 50187794 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyridin-4-ylmethyl)piperidine-4-carboxamide::CHEMBL387079 Disintegrin and metalloproteinase domain-containing protein 17 2.1 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187794&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22626996 104071620 CHEMBL387079 ZINC34801902 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347479 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)CN1CCOCC1)C(=O)NO InChI=1S/C23H31N3O7S/c1-2-3-14-33-19-4-6-20(7-5-19)34(30,31)18-23(22(28)24-29)8-10-26(11-9-23)21(27)17-25-12-15-32-16-13-25/h4-7,29H,8-18H2,1H3,(H,24,28) BNKOGVVBAYMLMZ-UHFFFAOYSA-N 50187782 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-morpholinoacetyl)piperidine-4-carboxamide::CHEMBL208841 Disintegrin and metalloproteinase domain-containing protein 17 3.4 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187782&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513821 104071608 CHEMBL208841 ZINC34801896 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347486 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccccc1C)C(=O)NO InChI=1S/C25H28N2O6S/c1-3-4-17-33-20-9-11-21(12-10-20)34(31,32)18-25(24(29)26-30)13-15-27(16-14-25)23(28)22-8-6-5-7-19(22)2/h5-12,30H,13-18H2,1-2H3,(H,26,29) LWFCUEQJXZSHMP-UHFFFAOYSA-N 50187784 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-methylbenzoyl)piperidine-4-carboxamide::CHEMBL211726 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187784&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413977 104071610 CHEMBL211726 ZINC34801891 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347488 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)N(C)c1ccccc1)C(=O)NO InChI=1S/C25H29N3O6S/c1-3-4-18-34-21-10-12-22(13-11-21)35(32,33)19-25(23(29)26-31)14-16-28(17-15-25)24(30)27(2)20-8-6-5-7-9-20/h5-13,31H,14-19H2,1-2H3,(H,26,29) WXIYDIUGDDBCAM-UHFFFAOYSA-N 50187780 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N4-hydroxy-N1-methyl-N1-phenylpiperidine-1,4-dicarboxamide::CHEMBL425251 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187780 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187780&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44414001 104071606 CHEMBL425251 ZINC34802400 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347501 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccccc1N)C(=O)NO InChI=1S/C24H27N3O6S/c1-2-3-16-33-18-8-10-19(11-9-18)34(31,32)17-24(23(29)26-30)12-14-27(15-13-24)22(28)20-6-4-5-7-21(20)25/h4-11,30H,12-17,25H2,1H3,(H,26,29) LNPBBURQSUEIHO-UHFFFAOYSA-N 50187789 1-(2-aminobenzoyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL212411 Disintegrin and metalloproteinase domain-containing protein 17 1.7 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187789 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187789&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413983 104071615 CHEMBL212411 ZINC34801889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347506 CCCCCNC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C23H33N3O6S/c1-3-5-7-14-24-22(28)26-15-12-23(13-16-26,21(27)25-29)18-33(30,31)20-10-8-19(9-11-20)32-17-6-4-2/h8-11,29H,3,5,7,12-18H2,1-2H3,(H,24,28)(H,25,27) QISXFHLASBPFBV-UHFFFAOYSA-N 50187798 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N4-hydroxy-N1-pentylpiperidine-1,4-dicarboxamide::CHEMBL212920 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187798&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413999 104071624 CHEMBL212920 ZINC34802399 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347508 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccc(C)cc1)C(=O)NO InChI=1S/C25H28N2O6S/c1-3-4-17-33-21-9-11-22(12-10-21)34(31,32)18-25(24(29)26-30)13-15-27(16-14-25)23(28)20-7-5-19(2)6-8-20/h5-12,30H,13-18H2,1-2H3,(H,26,29) KRGBAILWDVNOCW-UHFFFAOYSA-N 50187783 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(4-methylbenzoyl)piperidine-4-carboxamide::CHEMBL377862 Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187783&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413987 104071609 CHEMBL377862 ZINC34801899 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347510 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1ccccc1)C(=O)NO InChI=1S/C23H26N2O7S2/c1-2-3-17-32-19-9-11-20(12-10-19)33(28,29)18-23(22(26)24-27)13-15-25(16-14-23)34(30,31)21-7-5-4-6-8-21/h4-12,27H,13-18H2,1H3,(H,24,26) JOYZIODFRIKBIG-UHFFFAOYSA-N 50187793 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(phenylsulfonyl)piperidine-4-carboxamide::CHEMBL214287 Disintegrin and metalloproteinase domain-containing protein 17 2.5 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187793&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513782 104071619 CHEMBL214287 ZINC34802401 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347511 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)C1CCCCC1)C(=O)NO InChI=1S/C24H32N2O6S/c1-2-3-17-32-20-9-11-21(12-10-20)33(30,31)18-24(23(28)25-29)13-15-26(16-14-24)22(27)19-7-5-4-6-8-19/h9-12,19,29H,4-8,13-18H2,1H3,(H,25,28) HUBYDVFNYBGAGD-UHFFFAOYSA-N 50187799 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyclohexanecarbonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL212469 Disintegrin and metalloproteinase domain-containing protein 17 2.3 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187799&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413972 104071625 CHEMBL212469 ZINC36748596 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347515 COCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C21H28N2O7S/c1-3-4-14-30-17-5-7-18(8-6-17)31(27,28)16-21(20(25)22-26)10-12-23(13-11-21)19(24)9-15-29-2/h5-8,26H,9-16H2,1-2H3,(H,22,25) LIJQQAFTSYEDRO-UHFFFAOYSA-N 50187791 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(3-methoxypropanoyl)piperidine-4-carboxamide::CHEMBL377272 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187791&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413978 104071617 CHEMBL377272 ZINC34801892 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347516 CCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C21H28N2O6S/c1-3-5-15-29-17-7-9-18(10-8-17)30(27,28)16-21(20(25)22-26)11-13-23(14-12-21)19(24)6-4-2/h7-10,26H,4,6,11-16H2,1-2H3,(H,22,25) MTSOZTJGECJILJ-UHFFFAOYSA-N 50187796 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-butyryl-N-hydroxypiperidine-4-carboxamide::CHEMBL211487 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187796&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413975 104071622 CHEMBL211487 ZINC34801894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347519 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(C)=O)C(=O)NO InChI=1S/C19H24N2O6S/c1-3-4-13-27-16-5-7-17(8-6-16)28(25,26)14-19(18(23)20-24)9-11-21(12-10-19)15(2)22/h5-8,24H,9-14H2,1-2H3,(H,20,23) NPWNPFHGYNOBOO-UHFFFAOYSA-N 30140 CHEMBL380049::beta-sulfone piperidine hydroxamate, 2b Disintegrin and metalloproteinase domain-containing protein 17 2.1 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30140&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9801569 85147901 CHEMBL380049 ZINC03924190 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347528 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccncc1)C(=O)NO InChI=1S/C23H25N3O6S/c1-2-3-16-32-19-4-6-20(7-5-19)33(30,31)17-23(22(28)25-29)10-14-26(15-11-23)21(27)18-8-12-24-13-9-18/h4-9,12-13,29H,10-11,14-17H2,1H3,(H,25,28) SFHMNFHDIRPFKM-UHFFFAOYSA-N 50187795 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-isonicotinoylpiperidine-4-carboxamide::CHEMBL377317 Disintegrin and metalloproteinase domain-containing protein 17 2.1 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187795&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413982 104071621 CHEMBL377317 ZINC34801888 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347531 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccccc1)C(=O)NO InChI=1S/C24H26N2O6S/c1-2-3-17-32-20-9-11-21(12-10-20)33(30,31)18-24(23(28)25-29)13-15-26(16-14-24)22(27)19-7-5-4-6-8-19/h4-12,29H,13-18H2,1H3,(H,25,28) HNEDFPGSHTUVKZ-UHFFFAOYSA-N 30144 CHEMBL212481::beta-sulfone piperidine hydroxamate, 2c Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30144&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23513825 85147905 CHEMBL212481 ZINC34801890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347540 CCN(CC)C(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C22H31N3O6S/c1-4-7-16-31-18-8-10-19(11-9-18)32(29,30)17-22(20(26)23-28)12-14-25(15-13-22)21(27)24(5-2)6-3/h8-11,28H,5-6,12-17H2,1-3H3,(H,23,26) RBTIHKNARDNLNU-UHFFFAOYSA-N 50187779 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N1,N1-diethyl-N4-hydroxypiperidine-1,4-dicarboxamide::CHEMBL379287 Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187779 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187779&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44414002 104071605 CHEMBL379287 ZINC34801903 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347545 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(C)(=O)=O)C(=O)NO InChI=1S/C18H24N2O7S2/c1-3-4-13-27-15-5-7-16(8-6-15)29(25,26)14-18(17(21)19-22)9-11-20(12-10-18)28(2,23)24/h5-8,22H,9-14H2,1-2H3,(H,19,21) RNHOXGSFKJUDNY-UHFFFAOYSA-N 50187797 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(methylsulfonyl)piperidine-4-carboxamide::CHEMBL210084 Disintegrin and metalloproteinase domain-containing protein 17 2.3 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187797&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413991 104071623 CHEMBL210084 ZINC34801897 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347548 CCCCS(=O)(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C21H30N2O7S2/c1-3-5-15-30-18-7-9-19(10-8-18)31(26,27)17-21(20(24)22-25)11-13-23(14-12-21)32(28,29)16-6-4-2/h7-10,25H,4,6,11-17H2,1-2H3,(H,22,24) MXMCYIBSFFNNTF-UHFFFAOYSA-N 50187781 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(butylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL379763 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187781&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413997 104071607 CHEMBL379763 ZINC34801904 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50347549 CCCCCC(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C23H32N2O6S/c1-3-5-7-8-21(26)25-15-13-23(14-16-25,22(27)24-28)18-32(29,30)20-11-9-19(10-12-20)31-17-6-4-2/h9-12,28H,3,5,7-8,13-18H2,1-2H3,(H,24,27) ZUMRSIZQUOZFGG-UHFFFAOYSA-N 50187790 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-hexanoyl-N-hydroxypiperidine-4-carboxamide::CHEMBL212205 Disintegrin and metalloproteinase domain-containing protein 17 1.8 ChEMBL 10.1016/j.bmcl.2006.05.026 10.7270/Q2222TCJ 16723229 Park, K; Aplasca, A; Du, MT; Sun, L; Zhu, Y; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187790 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187790&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413979 104071616 CHEMBL212205 ZINC34801893 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50372814 ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22) ROSNVSQTEGHUKU-UHFFFAOYSA-N 11863 4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N-hydroxyoxane-4-carboxamide::CHEMBL440498::RS 130830::RS-130,830::alpha-tetrahydropyran beta-sulfone 1B Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1021/jm500981k 10.7270/Q28P628P 25264600 Nara, H; Sato, K; Naito, T; Mototani, H; Oki, H; Yamamoto, Y; Kuno, H; Santou, T; Kanzaki, N; Terauchi, J; Uchikawa, O; Kori, M Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11863&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search RS1 830C 3342298 46512375 CHEMBL440498 DB08490 ZINC01488366 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50372815 COc1cccc(CNC(=O)c2nc3ccc(F)c(OCCc4ccc(cc4)C(O)=O)c3c(=O)[nH]2)c1 InChI=1S/C26H22FN3O6/c1-35-18-4-2-3-16(13-18)14-28-25(32)23-29-20-10-9-19(27)22(21(20)24(31)30-23)36-12-11-15-5-7-17(8-6-15)26(33)34/h2-10,13H,11-12,14H2,1H3,(H,28,32)(H,33,34)(H,29,30,31) YNHGVYGMFAREOF-UHFFFAOYSA-N 50102750 CHEMBL3359091 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm500981k 10.7270/Q28P628P 25264600 Nara, H; Sato, K; Naito, T; Mototani, H; Oki, H; Yamamoto, Y; Kuno, H; Santou, T; Kanzaki, N; Terauchi, J; Uchikawa, O; Kori, M Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50102750 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50102750&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search WHH 3WV1 11576807 103999185 CHEMBL3359091 ZINC13863649 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50372816 COc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 InChI=1S/C17H15N3O3/c1-23-12-6-4-5-11(9-12)10-18-17(22)15-19-14-8-3-2-7-13(14)16(21)20-15/h2-9H,10H2,1H3,(H,18,22)(H,19,20,21) AARSEFXVCWMMKV-UHFFFAOYSA-N 50025159 CHEMBL3337869 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm500981k 10.7270/Q28P628P 25264600 Nara, H; Sato, K; Naito, T; Mototani, H; Oki, H; Yamamoto, Y; Kuno, H; Santou, T; Kanzaki, N; Terauchi, J; Uchikawa, O; Kori, M Takeda Pharmaceutical Co., Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50025159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50025159&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search WGG 3WV2 118987537 313065064 CHEMBL3337869 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379161 Oc1ccc(C[C@@H](CN2CCC[C@H]2CN2[C@H](Cc3ccc4ccccc4c3)CNC(=O)C2=O)N2C[C@H](Cc3ccc(O)cc3)N(CCC34CC5CC(CC(C5)C3)C4)C(=O)C2=O)cc1 InChI=1S/C52H61N5O6/c58-46-13-8-34(9-14-46)24-44(31-54-18-3-6-42(54)32-56-43(30-53-48(60)49(56)61)26-36-7-12-40-4-1-2-5-41(40)23-36)57-33-45(25-35-10-15-47(59)16-11-35)55(50(62)51(57)63)19-17-52-27-37-20-38(28-52)22-39(21-37)29-52/h1-2,4-5,7-16,23,37-39,42-45,58-59H,3,6,17-22,24-33H2,(H,53,60)/t37?,38?,39?,42-,43+,44-,45-,52?/m0/s1 YJKDBAIGNHAGFS-DRIZYNOISA-N 50104627 CHEMBL3593545 Disintegrin and metalloproteinase domain-containing protein 17 8100 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104627 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104627&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181992 104000554 CHEMBL3593545 ZINC26579662 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379162 CCCC[C@H]1CN([C@H](CN2CCC[C@H]2CN2[C@@H](CCC)CNC(=O)C2=O)Cc2ccc(O)cc2)C(=O)C(=O)N1CCC12CC3CC(CC(C3)C1)C2 InChI=1S/C41H61N5O5/c1-3-5-8-34-27-46(40(51)39(50)44(34)16-14-41-21-29-17-30(22-41)19-31(18-29)23-41)35(20-28-10-12-36(47)13-11-28)25-43-15-6-9-33(43)26-45-32(7-4-2)24-42-37(48)38(45)49/h10-13,29-35,47H,3-9,14-27H2,1-2H3,(H,42,48)/t29?,30?,31?,32-,33-,34-,35-,41?/m0/s1 YDHCZWMEVFTGOU-KOYPUVKGSA-N 50104628 CHEMBL3593544 Disintegrin and metalloproteinase domain-containing protein 17 6500 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104628&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181991 104000555 CHEMBL3593544 ZINC38153046 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379163 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@@H](Cc2ccc3ccccc3c2)N(CCC23CC4CC(CC(C4)C2)C3)C(=O)C1=O InChI=1S/C48H61N5O5/c1-2-6-39-28-49-44(55)45(56)52(39)30-40-9-5-17-50(40)29-41(23-32-11-14-43(54)15-12-32)53-31-42(24-33-10-13-37-7-3-4-8-38(37)22-33)51(46(57)47(53)58)18-16-48-25-34-19-35(26-48)21-36(20-34)27-48/h3-4,7-8,10-15,22,34-36,39-42,54H,2,5-6,9,16-21,23-31H2,1H3,(H,49,55)/t34?,35?,36?,39-,40-,41-,42+,48?/m0/s1 XEZAWDWDXUIILJ-IAIYMEMOSA-N 50104629 CHEMBL3593543 Disintegrin and metalloproteinase domain-containing protein 17 7900 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104629 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104629&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181990 104000556 CHEMBL3593543 ZINC26579323 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379164 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc3ccccc3c2)N(CCC23CC4CC(CC(C4)C2)C3)C(=O)C1=O InChI=1S/C48H61N5O5/c1-2-6-39-28-49-44(55)45(56)52(39)30-40-9-5-17-50(40)29-41(23-32-11-14-43(54)15-12-32)53-31-42(24-33-10-13-37-7-3-4-8-38(37)22-33)51(46(57)47(53)58)18-16-48-25-34-19-35(26-48)21-36(20-34)27-48/h3-4,7-8,10-15,22,34-36,39-42,54H,2,5-6,9,16-21,23-31H2,1H3,(H,49,55)/t34?,35?,36?,39-,40-,41-,42-,48?/m0/s1 XEZAWDWDXUIILJ-PSPHSCPFSA-N 50104630 CHEMBL3593542 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104630&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181989 104000557 CHEMBL3593542 ZINC26579111 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379165 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@@H](Cc2ccc(O)cc2)N(CCC23CC4CC(CC(C4)C2)C3)C(=O)C1=O InChI=1S/C44H59N5O6/c1-2-4-34-25-45-40(52)41(53)48(34)27-35-5-3-15-46(35)26-36(20-29-6-10-38(50)11-7-29)49-28-37(21-30-8-12-39(51)13-9-30)47(42(54)43(49)55)16-14-44-22-31-17-32(23-44)19-33(18-31)24-44/h6-13,31-37,50-51H,2-5,14-28H2,1H3,(H,45,52)/t31?,32?,33?,34-,35-,36-,37+,44?/m0/s1 LTJNQSQTVHCHJA-IQNRKXJZSA-N 50104631 CHEMBL3593541 Disintegrin and metalloproteinase domain-containing protein 17 5400 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104631&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181988 104000558 CHEMBL3593541 ZINC26577808 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379167 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc(O)cc2)N(CC2CCCC2)C(=O)C1=O InChI=1S/C38H51N5O6/c1-2-6-29-21-39-35(46)36(47)42(29)24-30-9-5-18-40(30)23-31(19-26-10-14-33(44)15-11-26)43-25-32(20-27-12-16-34(45)17-13-27)41(37(48)38(43)49)22-28-7-3-4-8-28/h10-17,28-32,44-45H,2-9,18-25H2,1H3,(H,39,46)/t29-,30-,31-,32-/m0/s1 YDWPLDCELAEATF-YDPTYEFTSA-N 50104632 CHEMBL3593362 Disintegrin and metalloproteinase domain-containing protein 17 35000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104632&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181852 104000559 CHEMBL3593362 ZINC38153055 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379168 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc(O)cc2)N(CCC23CC4CC(CC(C4)C2)C3)C(=O)C1=O InChI=1S/C44H59N5O6/c1-2-4-34-25-45-40(52)41(53)48(34)27-35-5-3-15-46(35)26-36(20-29-6-10-38(50)11-7-29)49-28-37(21-30-8-12-39(51)13-9-30)47(42(54)43(49)55)16-14-44-22-31-17-32(23-44)19-33(18-31)24-44/h6-13,31-37,50-51H,2-5,14-28H2,1H3,(H,45,52)/t31?,32?,33?,34-,35-,36-,37-,44?/m0/s1 LTJNQSQTVHCHJA-MDPQSTDRSA-N 50104633 CHEMBL3593361 Disintegrin and metalloproteinase domain-containing protein 17 5900 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104633&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181851 104000560 CHEMBL3593361 ZINC26640731 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379169 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc(O)cc2)N(CC(CC)c2ccccc2)C(=O)C1=O InChI=1S/C42H53N5O6/c1-3-9-33-24-43-39(50)40(51)46(33)27-34-12-8-21-44(34)26-35(22-29-13-17-37(48)18-14-29)47-28-36(23-30-15-19-38(49)20-16-30)45(41(52)42(47)53)25-31(4-2)32-10-6-5-7-11-32/h5-7,10-11,13-20,31,33-36,48-49H,3-4,8-9,12,21-28H2,1-2H3,(H,43,50)/t31?,33-,34-,35-,36-/m0/s1 FZUNFUBTNGTNHB-TZYWOTFASA-N 50104634 CHEMBL3593360 Disintegrin and metalloproteinase domain-containing protein 17 15000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104634&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181850 104000561 CHEMBL3593360 ZINC26638983 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379171 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc(O)cc2)N(CC2CCC2)C(=O)C1=O InChI=1S/C37H49N5O6/c1-2-5-28-20-38-34(45)35(46)41(28)23-29-8-4-17-39(29)22-30(18-25-9-13-32(43)14-10-25)42-24-31(19-26-11-15-33(44)16-12-26)40(36(47)37(42)48)21-27-6-3-7-27/h9-16,27-31,43-44H,2-8,17-24H2,1H3,(H,38,45)/t28-,29-,30-,31-/m0/s1 GMNBJLPEGPVJPY-ORYMTKCHSA-N 50104635 CHEMBL3593359 Disintegrin and metalloproteinase domain-containing protein 17 94000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104635&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181849 104000562 CHEMBL3593359 ZINC26579561 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379173 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc(O)cc2)N(CC2CCCCC2)C(=O)C1=O InChI=1S/C39H53N5O6/c1-2-7-30-22-40-36(47)37(48)43(30)25-31-10-6-19-41(31)24-32(20-27-11-15-34(45)16-12-27)44-26-33(21-28-13-17-35(46)18-14-28)42(38(49)39(44)50)23-29-8-4-3-5-9-29/h11-18,29-33,45-46H,2-10,19-26H2,1H3,(H,40,47)/t30-,31-,32-,33-/m0/s1 UVUQQKAHEHBGSC-YRCZKMHPSA-N 50104636 CHEMBL3593358 Disintegrin and metalloproteinase domain-containing protein 17 29000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104636&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181848 104000563 CHEMBL3593358 ZINC26579429 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379174 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc(O)cc2)N(CC23CC4CC(CC(C4)C2)C3)C(=O)C1=O InChI=1S/C43H57N5O6/c1-2-4-33-23-44-39(51)40(52)46(33)25-34-5-3-14-45(34)24-35(18-28-6-10-37(49)11-7-28)47-26-36(19-29-8-12-38(50)13-9-29)48(42(54)41(47)53)27-43-20-30-15-31(21-43)17-32(16-30)22-43/h6-13,30-36,49-50H,2-5,14-27H2,1H3,(H,44,51)/t30?,31?,32?,33-,34-,35-,36-,43?/m0/s1 ZLLUKOYZOWEAAX-IMQYSQPFSA-N 50104637 CHEMBL3593357 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104637&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181847 104000564 CHEMBL3593357 ZINC26577341 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379175 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@H](Cc1ccc(O)cc1)N1C[C@H](Cc2ccc(O)cc2)N(CC2CCC(CC2)C(C)(C)C)C(=O)C1=O InChI=1S/C43H61N5O6/c1-5-7-33-24-44-39(51)40(52)47(33)27-34-8-6-21-45(34)26-35(22-29-11-17-37(49)18-12-29)48-28-36(23-30-13-19-38(50)20-14-30)46(41(53)42(48)54)25-31-9-15-32(16-10-31)43(2,3)4/h11-14,17-20,31-36,49-50H,5-10,15-16,21-28H2,1-4H3,(H,44,51)/t31?,32?,33-,34-,35-,36-/m0/s1 JIELZJLPGICKLQ-QNTZKYAPSA-N 50104638 CHEMBL3593356 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104638&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181846 104000565 CHEMBL3593356 ZINC26578585 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379205 Oc1ccc(C[C@@H]2CNC(=O)C(=O)N2C[C@@H]2CCCN2C[C@@H](Cc2ccc3ccccc3c2)N2C[C@H](Cc3ccc(O)cc3)N(CCC34CC5CC(CC(C5)C3)C4)C(=O)C2=O)cc1 InChI=1S/C52H61N5O6/c58-46-13-8-34(9-14-46)24-43-30-53-48(60)49(61)56(43)32-42-6-3-18-54(42)31-44(26-36-7-12-40-4-1-2-5-41(40)23-36)57-33-45(25-35-10-15-47(59)16-11-35)55(50(62)51(57)63)19-17-52-27-37-20-38(28-52)22-39(21-37)29-52/h1-2,4-5,7-16,23,37-39,42-45,58-59H,3,6,17-22,24-33H2,(H,53,60)/t37?,38?,39?,42-,43+,44+,45-,52?/m0/s1 SWCOKZUOBSVFCL-NROLRVEYSA-N 50104622 CHEMBL3593550 Disintegrin and metalloproteinase domain-containing protein 17 100000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181997 104000550 CHEMBL3593550 ZINC26640722 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379206 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@@H](CC1CCCCC1)N1C[C@H](Cc2ccccc2)N(CCc2ccccc2)C(=O)C1=O InChI=1S/C40H55N5O4/c1-2-13-33-26-41-37(46)38(47)44(33)28-34-20-12-22-42(34)27-35(24-31-16-8-4-9-17-31)45-29-36(25-32-18-10-5-11-19-32)43(39(48)40(45)49)23-21-30-14-6-3-7-15-30/h3,5-7,10-11,14-15,18-19,31,33-36H,2,4,8-9,12-13,16-17,20-29H2,1H3,(H,41,46)/t33-,34-,35+,36-/m0/s1 ZEPWGRQYGKUKNA-KFIZHRIMSA-N 50104620 CHEMBL3593551 Disintegrin and metalloproteinase domain-containing protein 17 28000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104620&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181998 104000548 CHEMBL3593551 ZINC26579211 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379207 Oc1ccc(C[C@@H]2CNC(=O)C(=O)N2C[C@@H]2CCCN2C[C@@H](Cc2ccc3ccccc3c2)N2C[C@H](Cc3ccc(O)cc3)N(CCC34CC5CC(CC(C5)C3)C4)C(=O)C2=O)cc1 InChI=1S/C52H61N5O6/c58-46-13-8-34(9-14-46)24-43-30-53-48(60)49(61)56(43)32-42-6-3-18-54(42)31-44(26-36-7-12-40-4-1-2-5-41(40)23-36)57-33-45(25-35-10-15-47(59)16-11-35)55(50(62)51(57)63)19-17-52-27-37-20-38(28-52)22-39(21-37)29-52/h1-2,4-5,7-16,23,37-39,42-45,58-59H,3,6,17-22,24-33H2,(H,53,60)/t37?,38?,39?,42-,43+,44+,45-,52?/m0/s1 SWCOKZUOBSVFCL-NROLRVEYSA-N 50104622 CHEMBL3593550 Disintegrin and metalloproteinase domain-containing protein 17 1900 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181997 104000550 CHEMBL3593550 ZINC26640722 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379210 COC(=O)N1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCC(=CC1)c1ccccc1)C(=O)NO InChI=1S/C22H27N3O5/c1-30-21(28)25-14-22(9-10-22)13-17(19(26)23-29)18(25)20(27)24-11-7-16(8-12-24)15-5-3-2-4-6-15/h2-7,17-18,29H,8-14H2,1H3,(H,23,26)/t17-,18-/m0/s1 CKZHFOKQZRZCPF-ROUUACIJSA-N 50203527 (6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate::CHEMBL434567::methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203527&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11625778 104082621 CHEMBL434567 ZINC13985960 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363489 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCCCC1)C(=O)NO InChI=1S/C22H31N3O7S2/c1-2-3-17-32-19-7-9-20(10-8-19)33(28,29)18-22(21(26)23-27)11-15-25(16-12-22)34(30,31)24-13-5-4-6-14-24/h7-10,27H,4-6,11-18H2,1H3,(H,23,26) UFEAOVWYWYBIFX-UHFFFAOYSA-N 50197209 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(piperidin-1-ylsulfonyl)piperidine-4-carboxamide::CHEMBL231667 Disintegrin and metalloproteinase domain-containing protein 17 1.2 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197209 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197209&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429899 104078639 CHEMBL231667 ZINC28816906 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363490 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)CCN1CCOCC1)C(=O)NO InChI=1S/C23H33N3O8S2/c1-2-3-15-34-20-4-6-21(7-5-20)35(29,30)19-23(22(27)24-28)8-10-26(11-9-23)36(31,32)18-14-25-12-16-33-17-13-25/h4-7,28H,8-19H2,1H3,(H,24,27) KAWCOVYOZMDLKQ-UHFFFAOYSA-N 50197210 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-morpholinoethylsulfonyl)piperidine-4-carboxamide::CHEMBL234144 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197210 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197210&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429882 104078640 CHEMBL234144 ZINC28816871 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363504 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1c(Cl)cncc1Cl)C(=O)NO InChI=1S/C23H23Cl2N3O6S/c1-2-3-12-34-16-4-6-17(7-5-16)35(32,33)15-23(22(30)27-31)8-10-28(11-9-23)21(29)20-18(24)13-26-14-19(20)25/h4-7,13-14,31H,8-12,15H2,1H3,(H,27,30) IDHBZDJZPPEMGC-UHFFFAOYSA-N 50197220 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5-dichloroisonicotinoyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL391881 Disintegrin and metalloproteinase domain-containing protein 17 1300 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197220&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429905 104078650 CHEMBL391881 ZINC28816914 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363515 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)c1ccccn1)C(=O)NO InChI=1S/C22H25N3O5S/c1-2-3-16-30-18-7-9-19(10-8-18)31(28,29)17-22(21(26)24-27)11-14-25(15-12-22)20-6-4-5-13-23-20/h4-10,13,27H,11-12,14-17H2,1H3,(H,24,26) WHUGMPJJQOVPAC-UHFFFAOYSA-N 50197222 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyridin-2-yl)piperidine-4-carboxamide::CHEMBL234353 Disintegrin and metalloproteinase domain-containing protein 17 1.3 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429887 104078652 CHEMBL234353 ZINC28816884 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363516 COC[C@@H]1CCCN1S(=O)(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C23H33N3O8S2/c1-3-4-16-34-20-7-9-21(10-8-20)35(29,30)18-23(22(27)24-28)11-14-25(15-12-23)36(31,32)26-13-5-6-19(26)17-33-2/h7-10,19,28H,5-6,11-18H2,1-2H3,(H,24,27)/t19-/m0/s1 IASRCCATUJITDX-IBGZPJMESA-N 50197208 (S)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-(methoxymethyl)pyrrolidin-1-ylsulfonyl)piperidine-4-carboxamide::CHEMBL231878 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197208 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197208&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429902 104078638 CHEMBL231878 ZINC28816911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363519 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)c1nc2ccccc2o1)C(=O)NO InChI=1S/C24H25N3O6S/c1-2-3-16-32-18-8-10-19(11-9-18)34(30,31)17-24(22(28)26-29)12-14-27(15-13-24)23-25-20-6-4-5-7-21(20)33-23/h4-11,29H,12-17H2,1H3,(H,26,28) XWVXWDVYQZEQBA-UHFFFAOYSA-N 50197227 1-(benzo[d]oxazol-2-yl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL393550 Disintegrin and metalloproteinase domain-containing protein 17 1.1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197227&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429889 104078657 CHEMBL393550 ZINC28816888 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363526 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)C(=O)NO InChI=1S/C21H23ClN2O7S3/c1-2-3-14-31-16-4-6-17(7-5-16)33(27,28)15-21(20(25)23-26)10-12-24(13-11-21)34(29,30)19-9-8-18(22)32-19/h4-9,26H,10-15H2,1H3,(H,23,25) JOILTJHUYYDODY-UHFFFAOYSA-N 50197230 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(5-chlorothiophen-2-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234775 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197230 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197230&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429893 104078660 CHEMBL234775 ZINC28816898 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363530 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)C(=O)c1ccncc1)C(=O)NO InChI=1S/C23H25N3O6S/c1-2-3-16-32-19-4-6-20(7-5-19)33(30,31)17-23(22(28)25-29)10-14-26(15-11-23)21(27)18-8-12-24-13-9-18/h4-9,12-13,29H,10-11,14-17H2,1H3,(H,25,28) SFHMNFHDIRPFKM-UHFFFAOYSA-N 50187795 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-isonicotinoylpiperidine-4-carboxamide::CHEMBL377317 Disintegrin and metalloproteinase domain-containing protein 17 2.6 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187795&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44413982 104071621 CHEMBL377317 ZINC34801888 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363536 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)c1ccncc1)C(=O)NO InChI=1S/C22H25N3O5S/c1-2-3-16-30-19-4-6-20(7-5-19)31(28,29)17-22(21(26)24-27)10-14-25(15-11-22)18-8-12-23-13-9-18/h4-9,12-13,27H,10-11,14-17H2,1H3,(H,24,26) VRQPNJFSKYEBCN-UHFFFAOYSA-N 50197235 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyridin-4-yl)piperidine-4-carboxamide::CHEMBL234565 Disintegrin and metalloproteinase domain-containing protein 17 5.6 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197235 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197235&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429888 104078665 CHEMBL234565 ZINC28816886 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363537 CCC(CC)S(=O)(=O)N1CCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(CC1)C(=O)NO InChI=1S/C22H32N2O7S2/c1-4-7-16-31-18-8-10-20(11-9-18)32(27,28)17-22(21(25)23-26)12-14-24(15-13-22)33(29,30)19(5-2)6-3/h8-11,19,26H,5-6,12-17H2,1-3H3,(H,23,25) RCCBHNFHHCGOQM-UHFFFAOYSA-N 50197219 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pentan-3-ylsulfonyl)piperidine-4-carboxamide::CHEMBL392295 Disintegrin and metalloproteinase domain-containing protein 17 1.2 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197219&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429880 104078649 CHEMBL392295 ZINC28816867 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363540 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C1CCCC1)C(=O)NO InChI=1S/C22H30N2O7S2/c1-2-3-16-31-18-8-10-19(11-9-18)32(27,28)17-22(21(25)23-26)12-14-24(15-13-22)33(29,30)20-6-4-5-7-20/h8-11,20,26H,4-7,12-17H2,1H3,(H,23,25) VGMJDHAFWAQDDY-UHFFFAOYSA-N 50197233 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyclopentylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234351 Disintegrin and metalloproteinase domain-containing protein 17 1.3 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197233 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197233&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429885 104078663 CHEMBL234351 ZINC28816880 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363554 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H27N3O4/c1-16-14-18(21-6-4-5-7-22(21)26-16)15-32-20-10-8-19(9-11-20)25(3)12-13-28(24(25)30)17(2)23(29)27-31/h4-11,14,17,31H,12-13,15H2,1-3H3,(H,27,29)/t17-,25+/m1/s1 YDMIPBHQKFOFQW-NSYGIPOTSA-N 26526 (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide::BMCL181958 Compound 1::CHEMBL148169::IK682 Disintegrin and metalloproteinase domain-containing protein 17 0.560000 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26526&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 541 2FV5 6914621 56464963 40083 CHEMBL148169 DB07145 ZINC03820969 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363559 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCN(CC1)C(C)=O)C(=O)NO InChI=1S/C23H32N4O8S2/c1-3-4-17-35-20-5-7-21(8-6-20)36(31,32)18-23(22(29)24-30)9-11-26(12-10-23)37(33,34)27-15-13-25(14-16-27)19(2)28/h5-8,30H,9-18H2,1-2H3,(H,24,29) WUVJCBZUUQXYIT-UHFFFAOYSA-N 50197237 1-(4-acetylpiperazin-1-ylsulfonyl)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL231877 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197237 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197237&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429901 104078667 CHEMBL231877 ZINC28816910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363566 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCOCC1)C(=O)NO InChI=1S/C21H29N3O8S2/c1-2-3-14-32-18-4-6-19(7-5-18)33(27,28)17-21(20(25)22-26)8-10-23(11-9-21)34(29,30)24-12-15-31-16-13-24/h4-7,26H,8-17H2,1H3,(H,22,25) DUPLEMOAJXTDKP-UHFFFAOYSA-N 50197236 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(morpholinosulfonyl)piperidine-4-carboxamide::CHEMBL231666 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197236 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197236&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429898 104078666 CHEMBL231666 ZINC28816905 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363567 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N(C)C)C(=O)NO InChI=1S/C19H27N3O7S2/c1-4-5-14-29-16-6-8-17(9-7-16)30(25,26)15-19(18(23)20-24)10-12-22(13-11-19)31(27,28)21(2)3/h6-9,24H,10-15H2,1-3H3,(H,20,23) MGIMQKIBRRRYRM-UHFFFAOYSA-N 50197232 4-(4-but-2-ynyloxy-benzenesulfonylmethyl)-1-dimethylsulfamoyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL231665 Disintegrin and metalloproteinase domain-containing protein 17 1.8 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197232 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197232&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429897 104078662 CHEMBL231665 ZINC28816904 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363568 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C1CCCCC1)C(=O)NO InChI=1S/C23H32N2O7S2/c1-2-3-17-32-19-9-11-20(12-10-19)33(28,29)18-23(22(26)24-27)13-15-25(16-14-23)34(30,31)21-7-5-4-6-8-21/h9-12,21,27H,4-8,13-18H2,1H3,(H,24,26) KVLYVSHQXNTARE-UHFFFAOYSA-N 50197218 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyclohexylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234352 Disintegrin and metalloproteinase domain-containing protein 17 2.8 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197218&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429886 104078648 CHEMBL234352 ZINC28816882 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363570 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1cn(C)c(C)n1)C(=O)NO InChI=1S/C22H28N4O7S2/c1-4-5-14-33-18-6-8-19(9-7-18)34(29,30)16-22(21(27)24-28)10-12-26(13-11-22)35(31,32)20-15-25(3)17(2)23-20/h6-9,15,28H,10-14,16H2,1-3H3,(H,24,27) XAISFEMYYICOMZ-UHFFFAOYSA-N 50197216 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(1,2-dimethyl-1H-imidazol-4-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL234774 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197216&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429892 104078646 CHEMBL234774 ZINC28816896 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363579 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)c1c(C)noc1C)C(=O)NO InChI=1S/C22H27N3O8S2/c1-4-5-14-32-18-6-8-19(9-7-18)34(28,29)15-22(21(26)23-27)10-12-25(13-11-22)35(30,31)20-16(2)24-33-17(20)3/h6-9,27H,10-15H2,1-3H3,(H,23,26) BIGQJQKSDHOEOM-UHFFFAOYSA-N 50197225 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5-dimethylisoxazol-4-ylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-({[4-(BUT-2-YN-1-YLOXY)PHENYL]SULFONYL}METHYL)-1-[(3,5-DIMETHYLISOXAZOL-4-YL)SULFONYL]-N-HYDROXYPIPERIDINE-4-CARBOXAMIDE::CHEMBL234567 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197225&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search KGY 2I47 11963536 104078655 CHEMBL234567 ZINC28816892 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363580 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C1CC1)C(=O)NO InChI=1S/C20H26N2O7S2/c1-2-3-14-29-16-4-6-17(7-5-16)30(25,26)15-20(19(23)21-24)10-12-22(13-11-20)31(27,28)18-8-9-18/h4-7,18,24H,8-15H2,1H3,(H,21,23) HQGORWGMKQFFGB-UHFFFAOYSA-N 50197226 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(cyclopropylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL392505 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197226&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429884 104078656 CHEMBL392505 ZINC28816878 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363583 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)C1C(=O)NO InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,10-12H2,1-3H3,(H,18,20) CVZIHNYAZLXRRS-UHFFFAOYSA-N 50171543 4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::4-(4-But-2-ynyloxy-benzenesulfonyl)-2,2-dimethyl-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL382975 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171543&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search IH6 1ZXC 6323382 104057740 CHEMBL382975 ZINC28527693 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363585 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCCC1)C(=O)NO InChI=1S/C21H29N3O7S2/c1-2-3-16-31-18-6-8-19(9-7-18)32(27,28)17-21(20(25)22-26)10-14-24(15-11-21)33(29,30)23-12-4-5-13-23/h6-9,26H,4-5,10-17H2,1H3,(H,22,25) GGDBCZZATDMWMQ-UHFFFAOYSA-N 50197211 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyrrolidin-1-ylsulfonyl)piperidine-4-carboxamide::CHEMBL391880 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197211 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197211&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429900 104078641 CHEMBL391880 ZINC28816908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363591 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)N1CCC[C@@H]1CO)C(=O)NO InChI=1S/C22H31N3O8S2/c1-2-3-15-33-19-6-8-20(9-7-19)34(29,30)17-22(21(27)23-28)10-13-24(14-11-22)35(31,32)25-12-4-5-18(25)16-26/h6-9,18,26,28H,4-5,10-17H2,1H3,(H,23,27)/t18-/m1/s1 LOOGWNWWNBNMRC-GOSISDBHSA-N 50197224 (R)-4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-(hydroxymethyl)pyrrolidin-1-ylsulfonyl)piperidine-4-carboxamide::CHEMBL231879 Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197224&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429903 104078654 CHEMBL231879 ZINC28816912 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363596 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(Cc2ccncc2)CC1)C(=O)NO InChI=1S/C23H27N3O5S/c1-2-3-16-31-20-4-6-21(7-5-20)32(29,30)18-23(22(27)25-28)10-14-26(15-11-23)17-19-8-12-24-13-9-19/h4-9,12-13,28H,10-11,14-18H2,1H3,(H,25,27) XIQNNSMTTLQUTR-UHFFFAOYSA-N 50187794 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyridin-4-ylmethyl)piperidine-4-carboxamide::CHEMBL387079 Disintegrin and metalloproteinase domain-containing protein 17 2.1 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50187794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50187794&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22626996 104071620 CHEMBL387079 ZINC34801902 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363600 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H28N2O7S2/c1-4-5-14-29-17-6-8-18(9-7-17)30(25,26)15-20(19(23)21-24)10-12-22(13-11-20)31(27,28)16(2)3/h6-9,16,24H,10-15H2,1-3H3,(H,21,23) CEVLUPQNDFOYSI-UHFFFAOYSA-N 23500 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::CHEMBL209970::beta-sulfonyl hydroxamate analogue, 4 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23500&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11634234 50091761 CHEMBL209970 ZINC06718474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363602 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)Cc1ccncc1)C(=O)NO InChI=1S/C23H27N3O7S2/c1-2-3-16-33-20-4-6-21(7-5-20)34(29,30)18-23(22(27)25-28)10-14-26(15-11-23)35(31,32)17-19-8-12-24-13-9-19/h4-9,12-13,28H,10-11,14-18H2,1H3,(H,25,27) LYGIRBLDUCXHDY-UHFFFAOYSA-N 50197229 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyridin-4-ylmethylsulfonyl)piperidine-4-carboxamide::CHEMBL392294 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197229&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429879 104078659 CHEMBL392294 ZINC28816865 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363605 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(CC2CCN(CC2)C(C)(C)C)N(O)C=O)c2ccccc2n1 InChI=1S/C30H39N3O5S/c1-22-17-24(28-7-5-6-8-29(28)31-22)19-38-26-9-11-27(12-10-26)39(36,37)20-25(33(35)21-34)18-23-13-15-32(16-14-23)30(2,3)4/h5-12,17,21,23,25,35H,13-16,18-20H2,1-4H3 BUDIJDXJWOVXRJ-UHFFFAOYSA-N 50197217 CHEMBL400206::N-(3-(1-tert-butylpiperidin-4-yl)-1-(4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)propan-2-yl)-N-hydroxyformamide Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197217&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429877 104078647 CHEMBL400206 ZINC28816860 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50363606 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)CN1CCOCC1)C(=O)NO InChI=1S/C24H35N3O8S2/c1-3-4-15-35-21-5-7-22(8-6-21)36(30,31)19-24(23(28)25-29)9-11-27(12-10-24)37(32,33)20(2)18-26-13-16-34-17-14-26/h5-8,20,29H,9-19H2,1-2H3,(H,25,28) IYSKDTAJMOMROJ-UHFFFAOYSA-N 50197223 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(1-morpholinopropan-2-ylsulfonyl)piperidine-4-carboxamide::CHEMBL234145 Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1016/j.bmcl.2006.10.004 10.7270/Q2862G2M 17064892 Condon, JS; Joseph-McCarthy, D; Levin, JI; Lombart, HG; Lovering, FE; Sun, L; Wang, W; Xu, W; Zhang, Y Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50197223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50197223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44429883 104078653 CHEMBL234145 ZINC28816876 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379013 Cc1cc(COc2ccc(cc2)C(=O)NCc2n[nH]c(=O)[nH]2)c2ccccc2n1 InChI=1S/C21H19N5O3/c1-13-10-15(17-4-2-3-5-18(17)23-13)12-29-16-8-6-14(7-9-16)20(27)22-11-19-24-21(28)26-25-19/h2-10H,11-12H2,1H3,(H,22,27)(H2,24,25,26,28) HGNMRIKSORWTLJ-UHFFFAOYSA-N 50208345 4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)benzamide::CHEMBL228267 Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208345 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208345&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44426845 104085514 CHEMBL228267 ZINC28708249 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379014 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H27N3O4/c1-16-14-18(21-6-4-5-7-22(21)26-16)15-32-20-10-8-19(9-11-20)25(3)12-13-28(24(25)30)17(2)23(29)27-31/h4-11,14,17,31H,12-13,15H2,1-3H3,(H,27,29)/t17-,25+/m1/s1 YDMIPBHQKFOFQW-NSYGIPOTSA-N 26526 (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide::BMCL181958 Compound 1::CHEMBL148169::IK682 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26526&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 541 2FV5 6914621 56464963 40083 CHEMBL148169 DB07145 ZINC03820969 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379016 Cc1cc(COc2ccc(cc2)C(=O)N[C@H]2CN(C[C@@H]2c2n[nH]c(=O)[nH]2)C(=O)OC(C)(C)C)c2ccccc2n1 InChI=1S/C29H32N6O5/c1-17-13-19(21-7-5-6-8-23(21)30-17)16-39-20-11-9-18(10-12-20)26(36)31-24-15-35(28(38)40-29(2,3)4)14-22(24)25-32-27(37)34-33-25/h5-13,22,24H,14-16H2,1-4H3,(H,31,36)(H2,32,33,34,37)/t22-,24-/m0/s1 SBINJYYFUVHVNU-UPVQGACJSA-N 50208346 4-((2-methylquinolin-4-yl)methoxy)-N-((3R,4S)-4-(5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyrrolidin-3-yl)benzamide::CHEMBL389691 Disintegrin and metalloproteinase domain-containing protein 17 162 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208346 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208346&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44426848 104085515 CHEMBL389691 ZINC14190781 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379017 Cc1cc(COc2ccc(cc2)S(=O)(=O)NCc2n[nH]c(=O)[nH]2)c2ccccc2n1 InChI=1S/C20H19N5O4S/c1-13-10-14(17-4-2-3-5-18(17)22-13)12-29-15-6-8-16(9-7-15)30(27,28)21-11-19-23-20(26)25-24-19/h2-10,21H,11-12H2,1H3,(H2,23,24,25,26) GQLPTZZPKXZFQR-UHFFFAOYSA-N 50208341 4-((2-methylquinolin-4-yl)methoxy)-N-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)benzenesulfonamide::CHEMBL228268 Disintegrin and metalloproteinase domain-containing protein 17 439 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208341&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44426847 104085510 CHEMBL228268 ZINC28708253 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379022 Cc1cc(COc2ccc(cc2)C(=O)Nc2ccccc2-c2[nH]c(=O)[nH]c2O)c2ccccc2n1 InChI=1S/C27H22N4O4/c1-16-14-18(20-6-2-4-8-22(20)28-16)15-35-19-12-10-17(11-13-19)25(32)29-23-9-5-3-7-21(23)24-26(33)31-27(34)30-24/h2-14,33H,15H2,1H3,(H,29,32)(H2,30,31,34) VOBFYBKSOTYYNL-UHFFFAOYSA-N 50208347 CHEMBL229072::N-(2-(2,5-dioxoimidazolidin-4-yl)phenyl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208347 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208347&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10344465 104085516 CHEMBL229072 ZINC13976108 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373743 CN(C)c1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CCOC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C25H28N4O4/c1-29(2)23-14-18(19-5-3-4-6-21(19)26-23)13-16-7-9-17(10-8-16)24(30)27-22-11-12-33-15-20(22)25(31)28-32/h3-10,14,20,22,32H,11-13,15H2,1-2H3,(H,27,30)(H,28,31)/t20-,22+/m0/s1 NNFVDZPMKBJSBI-RBBKRZOGSA-N 50204385 (3R,4R)-4-(4-((2-(dimethylamino)quinolin-4-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234415 Disintegrin and metalloproteinase domain-containing protein 17 460 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204385&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431858 104083085 CHEMBL234415 ZINC28821965 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373745 Cc1cc(Cc2ccc(cc2)C(=O)NC2(CC(=O)NO)CCOCC2)c2ccccc2n1 InChI=1S/C25H27N3O4/c1-17-14-20(21-4-2-3-5-22(21)26-17)15-18-6-8-19(9-7-18)24(30)27-25(16-23(29)28-31)10-12-32-13-11-25/h2-9,14,31H,10-13,15-16H2,1H3,(H,27,30)(H,28,29) IBWSLBQVCNZYSS-UHFFFAOYSA-N 50204387 CHEMBL234032::N-(4-(2-(hydroxyamino)-2-oxoethyl)-tetrahydro-2H-pyran-4-yl)-4-((2-methylquinolin-4-yl)methyl)benzamide Disintegrin and metalloproteinase domain-containing protein 17 >3000 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204387 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204387&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431852 104083087 CHEMBL234032 ZINC28821957 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373746 Cc1cc(Oc2ccc(cc2)C(=O)N[C@@H]2CN(C[C@@H]2C(=O)NO)C(=O)OC(C)(C)C)c2ccccc2n1 InChI=1S/C27H30N4O6/c1-16-13-23(19-7-5-6-8-21(19)28-16)36-18-11-9-17(10-12-18)24(32)29-22-15-31(14-20(22)25(33)30-35)26(34)37-27(2,3)4/h5-13,20,22,35H,14-15H2,1-4H3,(H,29,32)(H,30,33)/t20-,22+/m0/s1 MVYIZSZGFKGROM-RBBKRZOGSA-N 50204388 (3S,4S)-tert-butyl 3-(hydroxycarbamoyl)-4-(4-(2-methylquinolin-4-yloxy)benzamido)pyrrolidine-1-carboxylate::CHEMBL398371 Disintegrin and metalloproteinase domain-containing protein 17 750 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204388 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204388&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431840 104083088 CHEMBL398371 ZINC28821945 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373749 Cc1nc2ccccc2c(Cc2ccc(cc2)C(=O)N[C@@H]2CCOC[C@@H]2C(=O)NO)c1C InChI=1S/C25H27N3O4/c1-15-16(2)26-22-6-4-3-5-19(22)20(15)13-17-7-9-18(10-8-17)24(29)27-23-11-12-32-14-21(23)25(30)28-31/h3-10,21,23,31H,11-14H2,1-2H3,(H,27,29)(H,28,30)/t21-,23+/m0/s1 XZEHDMODAFCGLX-JTHBVZDNSA-N 50204389 (3R,4R)-4-(4-((2,3-dimethylquinolin-4-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234417 Disintegrin and metalloproteinase domain-containing protein 17 85 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204389 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204389&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431861 104083089 CHEMBL234417 ZINC28821968 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373750 CCc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CCOC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C25H27N3O4/c1-2-19-14-18(20-5-3-4-6-22(20)26-19)13-16-7-9-17(10-8-16)24(29)27-23-11-12-32-15-21(23)25(30)28-31/h3-10,14,21,23,31H,2,11-13,15H2,1H3,(H,27,29)(H,28,30)/t21-,23+/m0/s1 IFJDXKMPVPOSFC-JTHBVZDNSA-N 50204390 (3R,4R)-4-(4-((2-ethylquinolin-4-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234225 Disintegrin and metalloproteinase domain-containing protein 17 78 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204390 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204390&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431855 104083090 CHEMBL234225 ZINC28821962 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373751 CCCCS(=O)(=O)N1C[C@@H](NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)[C@H](C1)C(=O)NO InChI=1S/C27H32N4O5S/c1-3-4-13-37(35,36)31-16-23(27(33)30-34)25(17-31)29-26(32)20-11-9-19(10-12-20)15-21-14-18(2)28-24-8-6-5-7-22(21)24/h5-12,14,23,25,34H,3-4,13,15-17H2,1-2H3,(H,29,32)(H,30,33)/t23-,25+/m0/s1 XDSDBWPXGOPPFL-UKILVPOCSA-N 50204391 (3S,4S)-1-(butylsulfonyl)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-3-carboxamide::CHEMBL233843 Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204391 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204391&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431850 104083091 CHEMBL233843 ZINC28821955 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373754 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2c3COCc3nc3ccccc23)cc1 InChI=1S/C25H25N3O5/c29-24(27-22-9-10-32-13-20(22)25(30)28-31)16-7-5-15(6-8-16)11-18-17-3-1-2-4-21(17)26-23-14-33-12-19(18)23/h1-8,20,22,31H,9-14H2,(H,27,29)(H,28,30)/t20-,22+/m0/s1 VCLBYIDCEBFPME-RBBKRZOGSA-N 50204394 (3R,4R)-4-(4-((1,3-dihydrofuro[3,4-b]quinolin-9-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234605 Disintegrin and metalloproteinase domain-containing protein 17 87 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204394 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204394&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431864 104083094 CHEMBL234605 ZINC28821972 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373755 Cc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CN(C[C@@H]2C(=O)NO)C(=O)C(C)(C)C)c2ccccc2n1 InChI=1S/C28H32N4O4/c1-17-13-20(21-7-5-6-8-23(21)29-17)14-18-9-11-19(12-10-18)25(33)30-24-16-32(27(35)28(2,3)4)15-22(24)26(34)31-36/h5-13,22,24,36H,14-16H2,1-4H3,(H,30,33)(H,31,34)/t22-,24+/m0/s1 JRRSWIJDZJXIAR-LADGPHEKSA-N 50204395 (3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)-1-pivaloylpyrrolidine-3-carboxamide::CHEMBL401453 Disintegrin and metalloproteinase domain-containing protein 17 95 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204395 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204395&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431849 104083095 CHEMBL401453 ZINC28821954 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373756 Cc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CNC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C23H24N4O3/c1-14-10-17(18-4-2-3-5-20(18)25-14)11-15-6-8-16(9-7-15)22(28)26-21-13-24-12-19(21)23(29)27-30/h2-10,19,21,24,30H,11-13H2,1H3,(H,26,28)(H,27,29)/t19-,21+/m0/s1 XIFKHHXNMFGMBU-PZJWPPBQSA-N 50204396 (3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-3-carboxamide::CHEMBL391873 Disintegrin and metalloproteinase domain-containing protein 17 67 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204396 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204396&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431843 104083096 CHEMBL391873 ZINC28821948 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373759 Cc1cc(Cc2cccc(c2)C(=O)N[C@@H]2COC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C23H23N3O4/c1-14-9-17(18-7-2-3-8-20(18)24-14)11-15-5-4-6-16(10-15)22(27)25-21-13-30-12-19(21)23(28)26-29/h2-10,19,21,29H,11-13H2,1H3,(H,25,27)(H,26,28)/t19-,21+/m0/s1 UNCGRKPTWVECFJ-PZJWPPBQSA-N 50204399 (3R,4S)-N-hydroxy-4-(3-((2-methylquinolin-4-yl)methyl)benzamido)-tetrahydrofuran-3-carboxamide::CHEMBL234033 Disintegrin and metalloproteinase domain-containing protein 17 130 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204399 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204399&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431853 104083099 CHEMBL234033 ZINC28821958 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373764 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2c3CCOc3nc3ccccc23)cc1 InChI=1S/C25H25N3O5/c29-23(26-22-10-11-32-14-20(22)24(30)28-31)16-7-5-15(6-8-16)13-19-17-3-1-2-4-21(17)27-25-18(19)9-12-33-25/h1-8,20,22,31H,9-14H2,(H,26,29)(H,28,30)/t20-,22+/m0/s1 MFRQARGKGNZAFB-RBBKRZOGSA-N 50204400 (3R,4R)-4-(4-((2,3-dihydrofuro[2,3-b]quinolin-4-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL392894 Disintegrin and metalloproteinase domain-containing protein 17 77 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204400 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204400&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431865 104083100 CHEMBL392894 ZINC28821973 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373768 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2c3CCCc3nc3ccccc23)cc1 InChI=1S/C26H27N3O4/c30-25(28-24-12-13-33-15-21(24)26(31)29-32)17-10-8-16(9-11-17)14-20-18-4-1-2-6-22(18)27-23-7-3-5-19(20)23/h1-2,4,6,8-11,21,24,32H,3,5,7,12-15H2,(H,28,30)(H,29,31)/t21-,24+/m0/s1 PXOOBCXHHRLMFT-XUZZJYLKSA-N 50204403 (3R,4R)-4-(4-((2,3-dihydro-1H-cyclopenta[b]quinolin-9-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234604 Disintegrin and metalloproteinase domain-containing protein 17 72 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204403 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204403&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431863 104083103 CHEMBL234604 ZINC28821971 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373769 CC#CCN1C[C@@H](NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)[C@H](C1)C(=O)NO InChI=1S/C27H28N4O3/c1-3-4-13-31-16-23(27(33)30-34)25(17-31)29-26(32)20-11-9-19(10-12-20)15-21-14-18(2)28-24-8-6-5-7-22(21)24/h5-12,14,23,25,34H,13,15-17H2,1-2H3,(H,29,32)(H,30,33)/t23-,25+/m0/s1 LBHPINDOHXBHHL-UKILVPOCSA-N 50204402 (3S,4S)-1-(but-2-ynyl)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-3-carboxamide::CHEMBL233842 Disintegrin and metalloproteinase domain-containing protein 17 110 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204402&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431848 104083102 CHEMBL233842 ZINC28821953 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373770 CN1C[C@@H](NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)[C@H](C1)C(=O)NO InChI=1S/C24H26N4O3/c1-15-11-18(19-5-3-4-6-21(19)25-15)12-16-7-9-17(10-8-16)23(29)26-22-14-28(2)13-20(22)24(30)27-31/h3-11,20,22,31H,12-14H2,1-2H3,(H,26,29)(H,27,30)/t20-,22+/m0/s1 VKZVNFAGQVZFTI-RBBKRZOGSA-N 50204398 (3S,4S)-N-hydroxy-1-methyl-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-3-carboxamide::CHEMBL429444 Disintegrin and metalloproteinase domain-containing protein 17 96 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204398 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204398&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431844 104083098 CHEMBL429444 ZINC28821949 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373773 Cc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CCOC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C24H25N3O4/c1-15-12-18(19-4-2-3-5-21(19)25-15)13-16-6-8-17(9-7-16)23(28)26-22-10-11-31-14-20(22)24(29)27-30/h2-9,12,20,22,30H,10-11,13-14H2,1H3,(H,26,28)(H,27,29)/t20-,22+/m0/s1 NMHJSIJTDAPUMQ-RBBKRZOGSA-N 50204392 (3R,4R)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234034 Disintegrin and metalloproteinase domain-containing protein 17 130 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204392 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204392&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 16730519 104083092 CHEMBL234034 ZINC28821959 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373777 COC(=O)N1C[C@@H](NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)[C@H](C1)C(=O)NO InChI=1S/C25H26N4O5/c1-15-11-18(19-5-3-4-6-21(19)26-15)12-16-7-9-17(10-8-16)23(30)27-22-14-29(25(32)34-2)13-20(22)24(31)28-33/h3-11,20,22,33H,12-14H2,1-2H3,(H,27,30)(H,28,31)/t20-,22+/m0/s1 ZASAXMMLZWOHBG-RBBKRZOGSA-N 50204386 (3S,4S)-methyl 3-(hydroxycarbamoyl)-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-1-carboxylate::CHEMBL233844 Disintegrin and metalloproteinase domain-containing protein 17 50 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204386 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204386&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431851 104083086 CHEMBL233844 ZINC28821956 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373778 Cc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CN(CC#C)C[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C26H26N4O3/c1-3-12-30-15-22(26(32)29-33)24(16-30)28-25(31)19-10-8-18(9-11-19)14-20-13-17(2)27-23-7-5-4-6-21(20)23/h1,4-11,13,22,24,33H,12,14-16H2,2H3,(H,28,31)(H,29,32)/t22-,24+/m0/s1 YIIFUMKWGPMPET-LADGPHEKSA-N 50204397 (3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)-1-(prop-2-ynyl)pyrrolidine-3-carboxamide::CHEMBL233629 Disintegrin and metalloproteinase domain-containing protein 17 86 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204397 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204397&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431847 104083097 CHEMBL233629 ZINC28821952 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373780 Cc1cc(COc2ccc(cc2)C(=O)N[C@@H]2CNC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C23H24N4O4/c1-14-10-16(18-4-2-3-5-20(18)25-14)13-31-17-8-6-15(7-9-17)22(28)26-21-12-24-11-19(21)23(29)27-30/h2-10,19,21,24,30H,11-13H2,1H3,(H,26,28)(H,27,29)/t19-,21+/m0/s1 UUIVGJHXTSUZJO-PZJWPPBQSA-N 50204405 (3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methoxy)benzamido)pyrrolidine-3-carboxamide::CHEMBL235997 Disintegrin and metalloproteinase domain-containing protein 17 75 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204405 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204405&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10273642 104083105 CHEMBL235997 ZINC03817633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373784 Cc1cc(Oc2ccc(cc2)C(=O)N[C@@H]2CNC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C22H22N4O4/c1-13-10-20(16-4-2-3-5-18(16)24-13)30-15-8-6-14(7-9-15)21(27)25-19-12-23-11-17(19)22(28)26-29/h2-10,17,19,23,29H,11-12H2,1H3,(H,25,27)(H,26,28)/t17-,19+/m0/s1 USWCXSQNRBBDGE-PKOBYXMFSA-N 50204407 (3S,4S)-N-hydroxy-4-(4-(2-methylquinolin-4-yloxy)benzamido)pyrrolidine-3-carboxamide::CHEMBL236204 Disintegrin and metalloproteinase domain-containing protein 17 920 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204407 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204407&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431841 104083107 CHEMBL236204 ZINC28821946 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373787 CC(C)c1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CCOC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C26H29N3O4/c1-16(2)24-14-19(20-5-3-4-6-22(20)27-24)13-17-7-9-18(10-8-17)25(30)28-23-11-12-33-15-21(23)26(31)29-32/h3-10,14,16,21,23,32H,11-13,15H2,1-2H3,(H,28,30)(H,29,31)/t21-,23+/m0/s1 OXYLZBTXCBUSJH-JTHBVZDNSA-N 50204408 (3R,4R)-N-hydroxy-4-(4-((2-isopropylquinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamide::CHEMBL401455 Disintegrin and metalloproteinase domain-containing protein 17 420 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204408 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204408&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431856 104083108 CHEMBL401455 ZINC28821963 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379028 Cc1cc(COc2ccc(cc2)C(=O)Nc2ccccc2C(=O)c2c[nH]c(=O)[nH]2)c2ccccc2n1 InChI=1S/C28H22N4O4/c1-17-14-19(21-6-2-4-8-23(21)30-17)16-36-20-12-10-18(11-13-20)27(34)31-24-9-5-3-7-22(24)26(33)25-15-29-28(35)32-25/h2-15H,16H2,1H3,(H,31,34)(H2,29,32,35) HVVGLHPJPUUJHI-UHFFFAOYSA-N 50208340 4-((2-methylquinolin-4-yl)methoxy)-N-(2-(2-oxo-2,3-dihydro-1H-imidazole-4-carbonyl)phenyl)benzamide::4-((2-methylquinolin-4-yl)methoxy)-N-(2-(2-oxo-2,3-dihydro-1H-imidazole-5-carbonyl)phenyl)benzamide::CHEMBL228320 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208340 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208340&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11202395 104085509 CHEMBL228320 ZINC28708259 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379029 Cc1cc(COc2ccc(cc2)S(=O)(=O)NCC2(C)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C22H22N4O5S/c1-14-11-15(18-5-3-4-6-19(18)24-14)12-31-16-7-9-17(10-8-16)32(29,30)23-13-22(2)20(27)25-21(28)26-22/h3-11,23H,12-13H2,1-2H3,(H2,25,26,27,28) FABNMTMBXQFDAV-UHFFFAOYSA-N 50208342 CHEMBL388124::N-((4-methyl-2,5-dioxoimidazolidin-4-yl)methyl)-4-((2-methylquinolin-4-yl)methoxy)benzenesulfonamide Disintegrin and metalloproteinase domain-containing protein 17 37 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208342&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10139040 104085511 CHEMBL388124 ZINC28708246 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379038 Cc1cc(COc2ccc(cc2)C(=O)Nc2ccccc2Cc2n[nH]c(=O)[nH]2)c2ccccc2n1 InChI=1S/C27H23N5O3/c1-17-14-20(22-7-3-5-9-24(22)28-17)16-35-21-12-10-18(11-13-21)26(33)29-23-8-4-2-6-19(23)15-25-30-27(34)32-31-25/h2-14H,15-16H2,1H3,(H,29,33)(H2,30,31,32,34) BSAORORNNRENRI-UHFFFAOYSA-N 50208343 4-((2-methylquinolin-4-yl)methoxy)-N-(2-((5-oxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)methyl)phenyl)benzamide::CHEMBL228318 Disintegrin and metalloproteinase domain-containing protein 17 34 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208343&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44426849 104085512 CHEMBL228318 ZINC28708255 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379050 Cc1cc(COc2ccc(cc2)C(=O)NCC2(C)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C23H22N4O4/c1-14-11-16(18-5-3-4-6-19(18)25-14)12-31-17-9-7-15(8-10-17)20(28)24-13-23(2)21(29)26-22(30)27-23/h3-11H,12-13H2,1-2H3,(H,24,28)(H2,26,27,29,30) BDTGEWQPSASMAZ-UHFFFAOYSA-N 50201248 CHEMBL229070::N-((4-methyl-2,5-dioxoimidazolidin-4-yl)methyl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 29 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50201248 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50201248&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10223757 104081134 CHEMBL229070 ZINC28708240 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379054 Cc1cc(COc2ccc(cc2)C(=O)Nc2ccccc2Cc2c[nH]c(=O)[nH]2)c2ccccc2n1 InChI=1S/C28H24N4O3/c1-18-14-21(24-7-3-5-9-26(24)30-18)17-35-23-12-10-19(11-13-23)27(33)32-25-8-4-2-6-20(25)15-22-16-29-28(34)31-22/h2-14,16H,15,17H2,1H3,(H,32,33)(H2,29,31,34) CLYVYZOSMYXOBC-UHFFFAOYSA-N 50208344 4-((2-methylquinolin-4-yl)methoxy)-N-(2-((2-oxo-2,3-dihydro-1H-imidazol-5-yl)methyl)phenyl)benzamide::CHEMBL228319 Disintegrin and metalloproteinase domain-containing protein 17 1600 ChEMBL 10.1016/j.bmcl.2007.02.076 10.7270/Q2ZC82J4 17368021 Sheppeck, JE; Gilmore, JL; Tebben, A; Xue, CB; Liu, RQ; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208344&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11397130 104085513 CHEMBL228319 ZINC28708257 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373801 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2cc(nc3ccccc23)C2CC2)cc1 InChI=1S/C26H27N3O4/c30-25(28-23-11-12-33-15-21(23)26(31)29-32)18-7-5-16(6-8-18)13-19-14-24(17-9-10-17)27-22-4-2-1-3-20(19)22/h1-8,14,17,21,23,32H,9-13,15H2,(H,28,30)(H,29,31)/t21-,23+/m0/s1 JKAWMUJNISILHP-JTHBVZDNSA-N 50204412 (3R,4R)-4-(4-((2-cyclopropylquinolin-4-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234416 Disintegrin and metalloproteinase domain-containing protein 17 230 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204412&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431859 104083112 CHEMBL234416 ZINC28821966 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373806 CCc1c(C)nc2ccccc2c1Cc1ccc(cc1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO InChI=1S/C26H29N3O4/c1-3-19-16(2)27-23-7-5-4-6-20(23)21(19)14-17-8-10-18(11-9-17)25(30)28-24-12-13-33-15-22(24)26(31)29-32/h4-11,22,24,32H,3,12-15H2,1-2H3,(H,28,30)(H,29,31)/t22-,24+/m0/s1 GQIOUHRIPZEFMT-LADGPHEKSA-N 50204410 (3R,4R)-4-(4-((3-ethyl-2-methylquinolin-4-yl)methyl)benzamido)-N-hydroxy-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234603 Disintegrin and metalloproteinase domain-containing protein 17 1200 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204410 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204410&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431862 104083110 CHEMBL234603 ZINC28821970 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373820 Cc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CN(C[C@@H]2C(=O)NO)C(=O)OC(C)(C)C)c2ccccc2n1 InChI=1S/C28H32N4O5/c1-17-13-20(21-7-5-6-8-23(21)29-17)14-18-9-11-19(12-10-18)25(33)30-24-16-32(15-22(24)26(34)31-36)27(35)37-28(2,3)4/h5-13,22,24,36H,14-16H2,1-4H3,(H,30,33)(H,31,34)/t22-,24+/m0/s1 CXBWDVDCCWRTQK-LADGPHEKSA-N 50204404 (3S,4S)-tert-butyl 3-(hydroxycarbamoyl)-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-1-carboxylate::CHEMBL399604 Disintegrin and metalloproteinase domain-containing protein 17 96 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204404 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204404&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431842 104083104 CHEMBL399604 ZINC28821947 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373821 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2cc(nc3ccccc23)C(F)(F)F)cc1 InChI=1S/C24H22F3N3O4/c25-24(26,27)21-12-16(17-3-1-2-4-19(17)28-21)11-14-5-7-15(8-6-14)22(31)29-20-9-10-34-13-18(20)23(32)30-33/h1-8,12,18,20,33H,9-11,13H2,(H,29,31)(H,30,32)/t18-,20+/m0/s1 RGJDIXGJLGTWJM-AZUAARDMSA-N 50204411 (3R,4R)-N-hydroxy-4-(4-((2-(trifluoromethyl)quinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234224 Disintegrin and metalloproteinase domain-containing protein 17 260 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204411 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204411&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431854 104083111 CHEMBL234224 ZINC28821961 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373832 Cc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CCC[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C24H25N3O3/c1-15-13-18(19-5-2-3-7-21(19)25-15)14-16-9-11-17(12-10-16)23(28)26-22-8-4-6-20(22)24(29)27-30/h2-3,5,7,9-13,20,22,30H,4,6,8,14H2,1H3,(H,26,28)(H,27,29)/t20-,22+/m0/s1 CKGRNUKOQHVJOB-RBBKRZOGSA-N 50204409 CHEMBL401454::N-((1R,2S)-2-(hydroxycarbamoyl)cyclopentyl)-4-((2-methylquinolin-4-yl)methyl)benzamide Disintegrin and metalloproteinase domain-containing protein 17 560 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204409 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204409&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 20728102 104083109 CHEMBL401454 ZINC28821960 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373833 CC(C)CN1C[C@@H](NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)[C@H](C1)C(=O)NO InChI=1S/C27H32N4O3/c1-17(2)14-31-15-23(27(33)30-34)25(16-31)29-26(32)20-10-8-19(9-11-20)13-21-12-18(3)28-24-7-5-4-6-22(21)24/h4-12,17,23,25,34H,13-16H2,1-3H3,(H,29,32)(H,30,33)/t23-,25+/m0/s1 VMWZNZVYBAZMKQ-UKILVPOCSA-N 50204401 (3S,4S)-N-hydroxy-1-isobutyl-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)pyrrolidine-3-carboxamide::CHEMBL392312 Disintegrin and metalloproteinase domain-containing protein 17 220 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204401 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204401&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431845 104083101 CHEMBL392312 ZINC28821950 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373836 Cc1cc(Cc2ccc(cc2)C(=O)N[C@@H]2CN(CC(C)(C)C)C[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C28H34N4O3/c1-18-13-21(22-7-5-6-8-24(22)29-18)14-19-9-11-20(12-10-19)26(33)30-25-16-32(17-28(2,3)4)15-23(25)27(34)31-35/h5-13,23,25,35H,14-17H2,1-4H3,(H,30,33)(H,31,34)/t23-,25+/m0/s1 KEGZCMGJDRKBBL-UKILVPOCSA-N 50204393 (3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methyl)benzamido)-1-neopentylpyrrolidine-3-carboxamide::CHEMBL234199 Disintegrin and metalloproteinase domain-containing protein 17 700 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204393 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204393&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431846 104083093 CHEMBL234199 ZINC28821951 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373848 Cc1cnc2ccccc2c1Cc1ccc(cc1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO InChI=1S/C24H25N3O4/c1-15-13-25-21-5-3-2-4-18(21)19(15)12-16-6-8-17(9-7-16)23(28)26-22-10-11-31-14-20(22)24(29)27-30/h2-9,13,20,22,30H,10-12,14H2,1H3,(H,26,28)(H,27,29)/t20-,22+/m0/s1 XKRVFVOPYXCFOD-RBBKRZOGSA-N 50204413 (3R,4R)-N-hydroxy-4-(4-((3-methylquinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamide::CHEMBL392686 Disintegrin and metalloproteinase domain-containing protein 17 98 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204413&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431860 104083113 CHEMBL392686 ZINC28821967 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50373850 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cc2cc(nc3ccccc23)N2CCOCC2)cc1 InChI=1S/C27H30N4O5/c32-26(29-24-9-12-36-17-22(24)27(33)30-34)19-7-5-18(6-8-19)15-20-16-25(31-10-13-35-14-11-31)28-23-4-2-1-3-21(20)23/h1-8,16,22,24,34H,9-15,17H2,(H,29,32)(H,30,33)/t22-,24+/m0/s1 ZVPKXROCOKUPBT-LADGPHEKSA-N 50204406 (3R,4R)-N-hydroxy-4-(4-((2-morpholinoquinolin-4-yl)methyl)benzamido)-tetrahydro-2H-pyran-3-carboxamide::CHEMBL234226 Disintegrin and metalloproteinase domain-containing protein 17 720 ChEMBL 10.1016/j.bmcl.2007.01.041 10.7270/Q2KK9BF4 17276676 Chen, XT; Ghavimi, B; Corbett, RL; Xue, CB; Liu, RQ; Covington, MB; Qian, M; Vaddi, KG; Christ, DD; Hartman, KD; Ribadeneira, MD; Trzaskos, JM; Newton, RC; Decicco, CP; Duan, JJ Bristol-Myers Squibb Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204406 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204406&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44431857 104083106 CHEMBL234226 ZINC28821964 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379146 O=C1NC[C@@H](Cc2ccccc2)N(C[C@@H]2CCCN2C[C@@H](CC2CCCCC2)N2C[C@H](Cc3ccccc3)N(CCc3ccccc3)C(=O)C2=O)C1=O InChI=1S/C44H55N5O4/c50-41-42(51)48(38(29-45-41)26-34-16-7-2-8-17-34)31-37-22-13-24-46(37)30-39(27-35-18-9-3-10-19-35)49-32-40(28-36-20-11-4-12-21-36)47(43(52)44(49)53)25-23-33-14-5-1-6-15-33/h1-2,4-8,11-12,14-17,20-21,35,37-40H,3,9-10,13,18-19,22-32H2,(H,45,50)/t37-,38+,39+,40-/m0/s1 QABDTPJMJYQBCF-KQQMQGIYSA-N 50104618 CHEMBL3593552 Disintegrin and metalloproteinase domain-containing protein 17 8500 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104618&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181999 104000546 CHEMBL3593552 ZINC26578755 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379147 Oc1ccc(C[C@H]2CN([C@H](CN3CCC[C@H]3CN3[C@@H](Cc4ccccc4)CNC(=O)C3=O)Cc3ccccc3)C(=O)C(=O)N2CCC23CC4CC(CC(C4)C2)C3)cc1 InChI=1S/C48H59N5O5/c54-43-15-13-35(14-16-43)25-42-32-53(47(58)46(57)51(42)19-17-48-26-36-20-37(27-48)22-38(21-36)28-48)41(24-34-10-5-2-6-11-34)30-50-18-7-12-39(50)31-52-40(29-49-44(55)45(52)56)23-33-8-3-1-4-9-33/h1-6,8-11,13-16,36-42,54H,7,12,17-32H2,(H,49,55)/t36?,37?,38?,39-,40-,41-,42-,48?/m0/s1 ILECMSXDFSLYHA-XOXLXNDPSA-N 50104619 CHEMBL3235912 Disintegrin and metalloproteinase domain-containing protein 17 11000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104619&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 78426757 104000547 CHEMBL3235912 ZINC26577802 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379151 CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]1CCCN1C[C@@H](CC1CCCCC1)N1C[C@H](Cc2ccccc2)N(CCc2ccccc2)C(=O)C1=O InChI=1S/C40H55N5O4/c1-2-13-33-26-41-37(46)38(47)44(33)28-34-20-12-22-42(34)27-35(24-31-16-8-4-9-17-31)45-29-36(25-32-18-10-5-11-19-32)43(39(48)40(45)49)23-21-30-14-6-3-7-15-30/h3,5-7,10-11,14-15,18-19,31,33-36H,2,4,8-9,12-13,16-17,20-29H2,1H3,(H,41,46)/t33-,34-,35+,36-/m0/s1 ZEPWGRQYGKUKNA-KFIZHRIMSA-N 50104620 CHEMBL3593551 Disintegrin and metalloproteinase domain-containing protein 17 4300 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104620&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181998 104000548 CHEMBL3593551 ZINC26579211 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379152 Oc1ccc(C[C@H]2CN([C@H](CC3CCCCC3)CN3CCC[C@H]3CN3[C@@H](Cc4ccccc4)CNC(=O)C3=O)C(=O)C(=O)N2CCc2ccccc2)cc1 InChI=1S/C44H55N5O5/c50-40-20-18-35(19-21-40)27-39-31-49(44(54)43(53)47(39)24-22-32-11-4-1-5-12-32)38(26-34-15-8-3-9-16-34)29-46-23-10-17-36(46)30-48-37(28-45-41(51)42(48)52)25-33-13-6-2-7-14-33/h1-2,4-7,11-14,18-21,34,36-39,50H,3,8-10,15-17,22-31H2,(H,45,51)/t36-,37-,38+,39-/m0/s1 RNBZJLOFSRJJMQ-RUPCYPOASA-N 50104621 CHEMBL3235911 Disintegrin and metalloproteinase domain-containing protein 17 5400 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104621&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 78426619 104000549 CHEMBL3235911 ZINC26580043 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379153 Oc1ccc(C[C@@H]2CNC(=O)C(=O)N2C[C@@H]2CCCN2C[C@@H](Cc2ccc3ccccc3c2)N2C[C@H](Cc3ccc(O)cc3)N(CCC34CC5CC(CC(C5)C3)C4)C(=O)C2=O)cc1 InChI=1S/C52H61N5O6/c58-46-13-8-34(9-14-46)24-43-30-53-48(60)49(61)56(43)32-42-6-3-18-54(42)31-44(26-36-7-12-40-4-1-2-5-41(40)23-36)57-33-45(25-35-10-15-47(59)16-11-35)55(50(62)51(57)63)19-17-52-27-37-20-38(28-52)22-39(21-37)29-52/h1-2,4-5,7-16,23,37-39,42-45,58-59H,3,6,17-22,24-33H2,(H,53,60)/t37?,38?,39?,42-,43+,44+,45-,52?/m0/s1 SWCOKZUOBSVFCL-NROLRVEYSA-N 50104622 CHEMBL3593550 Disintegrin and metalloproteinase domain-containing protein 17 4200 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181997 104000550 CHEMBL3593550 ZINC26640722 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379154 CCCC[C@H]1CN([C@H](CN2CCC[C@H]2CN2[C@H](Cc3ccc4ccccc4c3)CNC(=O)C2=O)Cc2ccc(O)cc2)C(=O)C(=O)N1CCC12CC3CC(CC(C3)C1)C2 InChI=1S/C49H63N5O5/c1-2-3-9-41-32-54(48(59)47(58)52(41)19-17-49-26-35-20-36(27-49)22-37(21-35)28-49)43(24-33-12-15-44(55)16-13-33)30-51-18-6-10-40(51)31-53-42(29-50-45(56)46(53)57)25-34-11-14-38-7-4-5-8-39(38)23-34/h4-5,7-8,11-16,23,35-37,40-43,55H,2-3,6,9-10,17-22,24-32H2,1H3,(H,50,56)/t35?,36?,37?,40-,41-,42+,43-,49?/m0/s1 DFINJLCZWBDBQX-KDNYSNCWSA-N 50104623 CHEMBL3593549 Disintegrin and metalloproteinase domain-containing protein 17 5700 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104623&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181996 318590317 CHEMBL3593549 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379157 Oc1ccc(C[C@@H](CN2CCC[C@H]2CN2[C@H](Cc3ccc4ccccc4c3)CNC(=O)C2=O)N2C[C@@H](Cc3ccc4ccccc4c3)N(CCC34CC5CC(CC(C5)C3)C4)C(=O)C2=O)cc1 InChI=1S/C56H63N5O5/c62-51-17-13-37(14-18-51)27-49(34-58-20-5-10-47(58)35-60-48(33-57-52(63)53(60)64)28-38-11-15-43-6-1-3-8-45(43)25-38)61-36-50(29-39-12-16-44-7-2-4-9-46(44)26-39)59(54(65)55(61)66)21-19-56-30-40-22-41(31-56)24-42(23-40)32-56/h1-4,6-9,11-18,25-26,40-42,47-50,62H,5,10,19-24,27-36H2,(H,57,63)/t40?,41?,42?,47-,48+,49-,50+,56?/m0/s1 JAQYUWLFIRGDEX-MZNQZOJJSA-N 50104624 CHEMBL3593548 Disintegrin and metalloproteinase domain-containing protein 17 5700 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104624&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181995 104000551 CHEMBL3593548 ZINC26579562 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379158 Oc1ccc(C[C@@H](CN2CCC[C@H]2CN2[C@H](Cc3ccc4ccccc4c3)CNC(=O)C2=O)N2C[C@H](Cc3ccc4ccccc4c3)N(CCC34CC5CC(CC(C5)C3)C4)C(=O)C2=O)cc1 InChI=1S/C56H63N5O5/c62-51-17-13-37(14-18-51)27-49(34-58-20-5-10-47(58)35-60-48(33-57-52(63)53(60)64)28-38-11-15-43-6-1-3-8-45(43)25-38)61-36-50(29-39-12-16-44-7-2-4-9-46(44)26-39)59(54(65)55(61)66)21-19-56-30-40-22-41(31-56)24-42(23-40)32-56/h1-4,6-9,11-18,25-26,40-42,47-50,62H,5,10,19-24,27-36H2,(H,57,63)/t40?,41?,42?,47-,48+,49-,50-,56?/m0/s1 JAQYUWLFIRGDEX-JEHAMROTSA-N 50104625 CHEMBL3593547 Disintegrin and metalloproteinase domain-containing protein 17 8400 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104625&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181994 104000552 CHEMBL3593547 ZINC26578054 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50379159 Oc1ccc(C[C@@H](CN2CCC[C@H]2CN2[C@H](Cc3ccc4ccccc4c3)CNC(=O)C2=O)N2C[C@@H](Cc3ccc(O)cc3)N(CCC34CC5CC(CC(C5)C3)C4)C(=O)C2=O)cc1 InChI=1S/C52H61N5O6/c58-46-13-8-34(9-14-46)24-44(31-54-18-3-6-42(54)32-56-43(30-53-48(60)49(56)61)26-36-7-12-40-4-1-2-5-41(40)23-36)57-33-45(25-35-10-15-47(59)16-11-35)55(50(62)51(57)63)19-17-52-27-37-20-38(28-52)22-39(21-37)29-52/h1-2,4-5,7-16,23,37-39,42-45,58-59H,3,6,17-22,24-33H2,(H,53,60)/t37?,38?,39?,42-,43+,44-,45+,52?/m0/s1 YJKDBAIGNHAGFS-XGCYGCKTSA-N 50104626 CHEMBL3593546 Disintegrin and metalloproteinase domain-containing protein 17 15000 ChEMBL 10.1021/acs.jmedchem.5b00354 10.7270/Q2MS3VJS 26192023 Knapinska, AM; Dreymuller, D; Ludwig, A; Smith, L; Golubkov, V; Sohail, A; Fridman, R; Giulianotti, M; LaVoi, TM; Houghten, RA; Fields, GB; Minond, D Florida Atlantic University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104626&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 122181993 104000553 CHEMBL3593546 ZINC26638988 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387749 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)C(C)C)C(=O)NO InChI=1S/C21H28N2O6S/c1-4-5-13-29-17-7-9-18(10-8-17)30(27,28)15-21(20(25)22-26)11-6-12-23(14-21)19(24)16(2)3/h7-10,16,26H,6,11-15H2,1-3H3,(H,22,25) UVFPNZAMZZIJLE-UHFFFAOYSA-N 50213942 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-isobutyrylpiperidine-3-carboxamide::CHEMBL250298 Disintegrin and metalloproteinase domain-containing protein 17 6.3 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442307 104089161 CHEMBL250298 ZINC28951478 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387752 CCC(C)C(=O)N1CCCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(C1)C(=O)NO InChI=1S/C22H30N2O6S/c1-4-6-14-30-18-8-10-19(11-9-18)31(28,29)16-22(21(26)23-27)12-7-13-24(15-22)20(25)17(3)5-2/h8-11,17,27H,5,7,12-16H2,1-3H3,(H,23,26) GRFJGGIFOFQTRL-UHFFFAOYSA-N 50213954 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-methylbutanoyl)piperidine-3-carboxamide::CHEMBL250299 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213954&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442308 104089173 CHEMBL250299 ZINC28951484 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387754 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H29N3O6S2/c1-4-5-12-21-17-7-9-18(10-8-17)30(26,27)15-20(19(24)22-25)11-6-13-23(14-20)31(28,29)16(2)3/h7-10,16,21,25H,6,11-15H2,1-3H3,(H,22,24) RZAVXBHMHDOVTM-UHFFFAOYSA-N 50213950 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-N-hydroxy-1-(isopropylsulfonyl)piperidine-3-carboxamide::CHEMBL250907 Disintegrin and metalloproteinase domain-containing protein 17 18 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213950&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442320 104089169 CHEMBL250907 ZINC28951534 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387756 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCNC1)C(=O)NO InChI=1S/C17H22N2O5S/c1-2-3-11-24-14-5-7-15(8-6-14)25(22,23)13-17(16(20)19-21)9-4-10-18-12-17/h5-8,18,21H,4,9-13H2,1H3,(H,19,20) CBVWAXQRTCTDDH-UHFFFAOYSA-N 50213953 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-3-carboxamide::CHEMBL250905 Disintegrin and metalloproteinase domain-containing protein 17 62 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213953&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442317 104089172 CHEMBL250905 ZINC28951524 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387758 CCOCc1ccc(cc1)C(=O)N1CCCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(C1)C(=O)NO InChI=1S/C27H32N2O7S/c1-3-5-17-36-23-11-13-24(14-12-23)37(33,34)20-27(26(31)28-32)15-6-16-29(19-27)25(30)22-9-7-21(8-10-22)18-35-4-2/h7-14,32H,4,6,15-20H2,1-2H3,(H,28,31) OAXXNDPRBWJXOJ-UHFFFAOYSA-N 50213956 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(4-(ethoxymethyl)benzoyl)-N-hydroxypiperidine-3-carboxamide::CHEMBL250504 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23655078 104089175 CHEMBL250504 ZINC28951508 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387759 CC#CCNc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)c1cccc(C)c1)C(=O)NO InChI=1S/C25H29N3O5S/c1-3-4-14-26-21-9-11-22(12-10-21)34(32,33)18-25(24(30)27-31)13-6-15-28(17-25)23(29)20-8-5-7-19(2)16-20/h5,7-12,16,26,31H,6,13-15,17-18H2,1-2H3,(H,27,30) ZUAUVLUKHSXGGD-UHFFFAOYSA-N 50213949 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-N-hydroxy-1-(3-methylbenzoyl)piperidine-3-carboxamide::CHEMBL250906 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213949&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442319 104089168 CHEMBL250906 ZINC28951530 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387770 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H28N2O7S2/c1-4-5-13-29-17-7-9-18(10-8-17)30(25,26)15-20(19(23)21-24)11-6-12-22(14-20)31(27,28)16(2)3/h7-10,16,24H,6,11-15H2,1-3H3,(H,21,23) YFKTVOCECCSHLJ-UHFFFAOYSA-N 50213945 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(isopropylsulfonyl)piperidine-3-carboxamide::CHEMBL250708 Disintegrin and metalloproteinase domain-containing protein 17 5.4 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213945&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442313 104089164 CHEMBL250708 ZINC28951503 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387771 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)c1ccccc1)C(=O)NO InChI=1S/C24H26N2O6S/c1-2-3-16-32-20-10-12-21(13-11-20)33(30,31)18-24(23(28)25-29)14-7-15-26(17-24)22(27)19-8-5-4-6-9-19/h4-6,8-13,29H,7,14-18H2,1H3,(H,25,28) JQJWNYAMOJOHCE-UHFFFAOYSA-N 50213941 1-benzoyl-3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-3-carboxamide::CHEMBL399097 Disintegrin and metalloproteinase domain-containing protein 17 5.8 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213941&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442309 104089160 CHEMBL399097 ZINC28951487 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387775 CCOC(=O)N1CCCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(C1)C(=O)NO InChI=1S/C20H26N2O7S/c1-3-5-13-29-16-7-9-17(10-8-16)30(26,27)15-20(18(23)21-25)11-6-12-22(14-20)19(24)28-4-2/h7-10,25H,4,6,11-15H2,1-2H3,(H,21,23) PPNXUTAPILQZQN-UHFFFAOYSA-N 50213946 CHEMBL250094::ethyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213946&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442304 104089165 CHEMBL250094 ZINC28951467 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387777 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)c1ccccc1C)C(=O)NO InChI=1S/C25H28N2O6S/c1-3-4-16-33-20-10-12-21(13-11-20)34(31,32)18-25(24(29)26-30)14-7-15-27(17-25)23(28)22-9-6-5-8-19(22)2/h5-6,8-13,30H,7,14-18H2,1-2H3,(H,26,29) SQWKFISUTRRKSE-UHFFFAOYSA-N 50213951 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(2-methylbenzoyl)piperidine-3-carboxamide::CHEMBL250502 Disintegrin and metalloproteinase domain-containing protein 17 1.7 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213951&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442310 104089170 CHEMBL250502 ZINC28951492 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387780 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)OC(C)(C)C)C(=O)NO InChI=1S/C22H30N2O7S/c1-5-6-14-30-17-8-10-18(11-9-17)32(28,29)16-22(19(25)23-27)12-7-13-24(15-22)20(26)31-21(2,3)4/h8-11,27H,7,12-16H2,1-4H3,(H,23,25) NYRVSWKULSLJMD-UHFFFAOYSA-N 50213943 CHEMBL250297::tert-butyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213943&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442306 104089162 CHEMBL250297 ZINC28951474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387784 CCN(CC)C(=O)N1CCCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(C1)C(=O)NO InChI=1S/C22H31N3O6S/c1-4-7-15-31-18-9-11-19(12-10-18)32(29,30)17-22(20(26)23-28)13-8-14-25(16-22)21(27)24(5-2)6-3/h9-12,28H,5-6,8,13-17H2,1-3H3,(H,23,26) NSSBNBOQWRPCCV-UHFFFAOYSA-N 50213947 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N1,N1-diethyl-N3-hydroxypiperidine-1,3-dicarboxamide::CHEMBL399929 Disintegrin and metalloproteinase domain-containing protein 17 9.6 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442316 104089166 CHEMBL399929 ZINC28951520 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387791 CCOC(=O)N1CCCC(CS(=O)(=O)c2ccc(NCC#CC)cc2)(C1)C(=O)NO InChI=1S/C20H27N3O6S/c1-3-5-12-21-16-7-9-17(10-8-16)30(27,28)15-20(18(24)22-26)11-6-13-23(14-20)19(25)29-4-2/h7-10,21,26H,4,6,11-15H2,1-2H3,(H,22,24) UAIMSPBCAMKARB-UHFFFAOYSA-N 50213957 CHEMBL446456::ethyl 3-((4-(but-2-ynylamino)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 21 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442318 104089176 CHEMBL446456 ZINC28951527 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387793 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)Cc1ccccc1)C(=O)NO InChI=1S/C24H28N2O7S2/c1-2-3-16-33-21-10-12-22(13-11-21)34(29,30)19-24(23(27)25-28)14-7-15-26(18-24)35(31,32)17-20-8-5-4-6-9-20/h4-6,8-13,28H,7,14-19H2,1H3,(H,25,27) ZXFJUXBYVRDBQU-UHFFFAOYSA-N 50213939 1-(benzylsulfonyl)-3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxypiperidine-3-carboxamide::CHEMBL250709 Disintegrin and metalloproteinase domain-containing protein 17 4.1 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213939 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213939&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442314 104089158 CHEMBL250709 ZINC28951512 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387794 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)c1ccc(C)cc1)C(=O)NO InChI=1S/C25H28N2O6S/c1-3-4-16-33-21-10-12-22(13-11-21)34(31,32)18-25(24(29)26-30)14-5-15-27(17-25)23(28)20-8-6-19(2)7-9-20/h6-13,30H,5,14-18H2,1-2H3,(H,26,29) LEMMSOIQHPOJRA-UHFFFAOYSA-N 50213955 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(4-methylbenzoyl)piperidine-3-carboxamide::CHEMBL399098 Disintegrin and metalloproteinase domain-containing protein 17 8.8 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213955&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442312 104089174 CHEMBL399098 ZINC28951499 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387734 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)OCC(C)C)C(=O)NO InChI=1S/C22H30N2O7S/c1-4-5-13-30-18-7-9-19(10-8-18)32(28,29)16-22(20(25)23-27)11-6-12-24(15-22)21(26)31-14-17(2)3/h7-10,17,27H,6,11-16H2,1-3H3,(H,23,25) AGMWQNDXCWDRDZ-UHFFFAOYSA-N 50213944 CHEMBL399096::isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 3.2 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213944&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442305 104089163 CHEMBL399096 ZINC28951470 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387736 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)S(=O)(=O)Cc1ccncc1)C(=O)NO InChI=1S/C23H27N3O7S2/c1-2-3-15-33-20-5-7-21(8-6-20)34(29,30)18-23(22(27)25-28)11-4-14-26(17-23)35(31,32)16-19-9-12-24-13-10-19/h5-10,12-13,28H,4,11,14-18H2,1H3,(H,25,27) KLUBFNJJJWONQA-UHFFFAOYSA-N 50213940 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(pyridin-4-ylmethylsulfonyl)piperidine-3-carboxamide::CHEMBL250710 Disintegrin and metalloproteinase domain-containing protein 17 5.9 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213940&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442315 104089159 CHEMBL250710 ZINC28951516 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387741 COC(=O)N1CCCC(CS(=O)(=O)c2ccc(OCC#CC)cc2)(C1)C(=O)NO InChI=1S/C19H24N2O7S/c1-3-4-12-28-15-6-8-16(9-7-15)29(25,26)14-19(17(22)20-24)10-5-11-21(13-19)18(23)27-2/h6-9,24H,5,10-14H2,1-2H3,(H,20,22) RZISBFWRHNXABZ-UHFFFAOYSA-N 50213948 CHEMBL250093::methyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213948&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442303 104089167 CHEMBL250093 ZINC28951464 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50387742 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)c1cccc(C)c1)C(=O)NO InChI=1S/C25H28N2O6S/c1-3-4-15-33-21-9-11-22(12-10-21)34(31,32)18-25(24(29)26-30)13-6-14-27(17-25)23(28)20-8-5-7-19(2)16-20/h5,7-12,16,30H,6,13-15,17-18H2,1-2H3,(H,26,29) RYUNWXPVOIGBCD-UHFFFAOYSA-N 50213952 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-N-hydroxy-1-(3-methylbenzoyl)piperidine-3-carboxamide::CHEMBL250503 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2007.05.022 10.7270/Q2CN73K3 17531482 Lombart, HG; Feyfant, E; Joseph-McCarthy, D; Huang, A; Lovering, F; Sun, L; Zhu, Y; Zeng, C; Zhang, Y; Levin, J Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213952&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442311 104089171 CHEMBL250503 ZINC28951495 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403963 CC(Cc1cc2cc(C)ccc2oc1=O)C(=O)NO InChI=1S/C14H15NO4/c1-8-3-4-12-10(5-8)7-11(14(17)19-12)6-9(2)13(16)15-18/h3-5,7,9,18H,6H2,1-2H3,(H,15,16) HNNDIXHHVAZLIV-UHFFFAOYSA-N 50224956 CHEMBL253710::N-hydroxy-2-methyl-3-(6-methyl-2-oxo-2H-chromen-3-yl)-propionamide Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15987326 104096469 CHEMBL253710 ZINC28979003 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403968 Cc1ccc2oc(=O)c(CC(CC=C)C(=O)NO)cc2c1 InChI=1S/C16H17NO4/c1-3-4-11(15(18)17-20)8-13-9-12-7-10(2)5-6-14(12)21-16(13)19/h3,5-7,9,11,20H,1,4,8H2,2H3,(H,17,18) JSQFQIGSGKOPJH-UHFFFAOYSA-N 50224960 2-(6-methyl-2-oxo-2H-chromen-3-ylmethyl)-pent-4-enoic acid hydroxyamide::CHEMBL253711 Disintegrin and metalloproteinase domain-containing protein 17 30 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224960&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15987412 104096473 CHEMBL253711 ZINC28979010 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403969 Cc1ccc2oc(=O)c(CC(Cc3ccccc3)C(=O)NO)cc2c1 InChI=1S/C20H19NO4/c1-13-7-8-18-15(9-13)11-17(20(23)25-18)12-16(19(22)21-24)10-14-5-3-2-4-6-14/h2-9,11,16,24H,10,12H2,1H3,(H,21,22) UOINUECLJZQMHR-UHFFFAOYSA-N 50224961 2-benzyl-N-hydroxy-3-(6-methyl-2-oxo-2H-chromen-3-yl)-propionamide::CHEMBL402030 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986113 104096474 CHEMBL402030 ZINC28979017 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403971 ONC(=O)CCc1cc2cc(Cl)ccc2oc1=O InChI=1S/C12H10ClNO4/c13-9-2-3-10-8(6-9)5-7(12(16)18-10)1-4-11(15)14-17/h2-3,5-6,17H,1,4H2,(H,14,15) BGTGOVQBCQMVIR-UHFFFAOYSA-N 50224962 3-(6-chloro-2-oxo-2H-chromen-3-yl)-N-hydroxy-propanamide::CHEMBL267854 Disintegrin and metalloproteinase domain-containing protein 17 550 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224962&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44446273 104096475 CHEMBL267854 ZINC28978958 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403973 C\C=C\C=C/C=C1\COC(=O)C(CCC(=O)NO)=C1 InChI=1S/C14H17NO4/c1-2-3-4-5-6-11-9-12(14(17)19-10-11)7-8-13(16)15-18/h2-6,9,18H,7-8,10H2,1H3,(H,15,16)/b3-2+,5-4-,11-6- LCTLPROJUJRGOK-OYGGHGNESA-N 50224959 3-(5-(hexa-2,4-dienylidene)-2-oxo-5,6-dihydro-2H-pyran-3-yl)-N-hydroxypropanamide::CHEMBL253313 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224959&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44446267 104096472 CHEMBL253313 ZINC28978923 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403974 ONC(=O)CCc1cc2cc(Br)ccc2oc1=O InChI=1S/C12H10BrNO4/c13-9-2-3-10-8(6-9)5-7(12(16)18-10)1-4-11(15)14-17/h2-3,5-6,17H,1,4H2,(H,14,15) QBKGBIIDSAFPRG-UHFFFAOYSA-N 50224957 3-(6-bromo-2-oxo-2H-chromen-3-yl)-N-hydroxy-propanamide::CHEMBL253694 Disintegrin and metalloproteinase domain-containing protein 17 840 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44446275 104096470 CHEMBL253694 ZINC28978967 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403978 ONC(=O)CCc1cc2ccccc2oc1=O InChI=1S/C12H11NO4/c14-11(13-16)6-5-9-7-8-3-1-2-4-10(8)17-12(9)15/h1-4,7,16H,5-6H2,(H,13,14) HJRCGMHZQDXQAO-UHFFFAOYSA-N 50224963 CHEMBL252674::N-hydroxy-3-(2-oxo-2H-chromen-3-yl)propanamide Disintegrin and metalloproteinase domain-containing protein 17 150 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44446270 104096476 CHEMBL252674 ZINC28978944 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403979 COc1ccc2oc(=O)c(CC(C)C(=O)NO)cc2c1 InChI=1S/C14H15NO5/c1-8(13(16)15-18)5-10-6-9-7-11(19-2)3-4-12(9)20-14(10)17/h3-4,6-8,18H,5H2,1-2H3,(H,15,16) ZKDYQMMAIWPWGK-UHFFFAOYSA-N 50224954 CHEMBL252693::N-hydroxy-2-((6-methoxy-2H-chromen-3-yl)methyl)propanamide Disintegrin and metalloproteinase domain-containing protein 17 36 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224954&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44446280 104096467 CHEMBL252693 ZINC28978997 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403981 COc1ccc2oc(=O)c(CCC(=O)NO)cc2c1 InChI=1S/C13H13NO5/c1-18-10-3-4-11-9(7-10)6-8(13(16)19-11)2-5-12(15)14-17/h3-4,6-7,17H,2,5H2,1H3,(H,14,15) JUDXBTMVZVWJNP-UHFFFAOYSA-N 50224955 CHEMBL402990::N-hydroxy-3-(6-methoxy-2-oxo-2H-chromen-3-yl) Disintegrin and metalloproteinase domain-containing protein 17 110 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224955&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44446277 104096468 CHEMBL402990 ZINC28978979 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403984 CC(C)(C)c1ccc2oc(=O)c(CCC(=O)NO)cc2c1 InChI=1S/C16H19NO4/c1-16(2,3)12-5-6-13-11(9-12)8-10(15(19)21-13)4-7-14(18)17-20/h5-6,8-9,20H,4,7H2,1-3H3,(H,17,18) OMHMZZGGFHEFEP-UHFFFAOYSA-N 50224964 3-(6-tert-butyl-2-oxo-2H-chromen-3-yl)-N-hydroxypropanamide::CHEMBL402991 Disintegrin and metalloproteinase domain-containing protein 17 12400 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224964&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44446278 104096477 CHEMBL402991 ZINC28978983 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50403985 Cc1ccc2oc(=O)c(CCC(=O)NO)cc2c1 InChI=1S/C13H13NO4/c1-8-2-4-11-10(6-8)7-9(13(16)18-11)3-5-12(15)14-17/h2,4,6-7,17H,3,5H2,1H3,(H,14,15) IMWYAYZRQVPCBO-UHFFFAOYSA-N 50224958 CHEMBL253489::N-hydroxy-3-(6-methyl-2-oxo-2H-chromen-3-yl)propanamide Disintegrin and metalloproteinase domain-containing protein 17 60 ChEMBL 10.1016/j.bmc.2007.09.014 10.7270/Q2QF8SM7 17936631 Chun, K; Park, SK; Kim, HM; Choi, Y; Kim, MH; Park, CH; Joe, BY; Chun, TG; Choi, HM; Lee, HY; Hong, SH; Kim, MS; Nam, KY; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224958&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24882385 104096471 CHEMBL253489 ZINC28978950 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50417885 CCN(C(=O)c1ccc(CNc2nc(NCCN3CCN(C)CC3)nc(n2)N2CCc3cc(OC)c(OC)cc3C2)cc1)c1cccc(C)c1 InChI=1S/C38H49N9O3/c1-6-47(32-9-7-8-27(2)22-32)35(48)29-12-10-28(11-13-29)25-40-37-41-36(39-15-17-45-20-18-44(3)19-21-45)42-38(43-37)46-16-14-30-23-33(49-4)34(50-5)24-31(30)26-46/h7-13,22-24H,6,14-21,25-26H2,1-5H3,(H2,39,40,41,42,43) CDVZHXHORLPPIL-UHFFFAOYSA-N 50122449 CHEMBL3622483 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/acsmedchemlett.5b00138 10.7270/Q2416ZWQ 26288689 Ding, Y; O'Keefe, H; DeLorey, JL; Israel, DI; Messer, JA; Chiu, CH; Skinner, SR; Matico, RE; Murray-Thompson, MF; Li, F; Clark, MA; Cuozzo, JW; Arico-Muendel, C; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50122449 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50122449&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329941 104015120 CHEMBL3622483 ZINC13487169 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50442670 CC(C)[C@@H](N(CC(=O)NCCc1ccc(cc1)S(N)(=O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO InChI=1S/C27H32N4O8S2/c1-19(2)26(27(33)30-34)31(18-25(32)29-17-16-20-8-12-23(13-9-20)40(28,35)36)41(37,38)24-14-10-22(11-15-24)39-21-6-4-3-5-7-21/h3-15,19,26,34H,16-18H2,1-2H3,(H,29,32)(H,30,33)(H2,28,35,36)/t26-/m1/s1 GSWRTFGMHRKLKT-AREMUKBSSA-N 50246599 CHEMBL471537::N-(4-Phenoxybenzenesulfonyl)-N-{[2-(4-sulfamoylphenyl)ethylcarbamoyl]methyl}-D-valinehydroxamic Acid Disintegrin and metalloproteinase domain-containing protein 17 55 ChEMBL 10.1021/jm800964f 10.7270/Q2XK8FDN 19053764 Marques, SM; Nuti, E; Rossello, A; Supuran, CT; Tuccinardi, T; Martinelli, A; Santos, MA Instituto Superior Técnico http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50246599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50246599&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25147773 104101989 CHEMBL471537 ZINC44417816 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50442725 CC(C)[C@@H](N(CC(O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO InChI=1S/C19H22N2O7S/c1-13(2)18(19(24)20-25)21(12-17(22)23)29(26,27)16-10-8-15(9-11-16)28-14-6-4-3-5-7-14/h3-11,13,18,25H,12H2,1-2H3,(H,20,24)(H,22,23)/t18-/m1/s1 KBZNOZAJAJRTII-GOSISDBHSA-N 50273426 CHEMBL515980::N-(4-Phenoxybenzenesulfonyl)-N-hydroxycarbonylmethyl-D-valinehydroxamicAcid Disintegrin and metalloproteinase domain-containing protein 17 2290 ChEMBL 10.1021/jm800964f 10.7270/Q2XK8FDN 19053764 Marques, SM; Nuti, E; Rossello, A; Supuran, CT; Tuccinardi, T; Martinelli, A; Santos, MA Instituto Superior Técnico http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50273426 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50273426&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25180867 104117552 CHEMBL515980 ZINC40848697 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432339 O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1 InChI=1S/C15H14O3S2/c16-20(17,11-14-10-19-14)15-8-6-13(7-9-15)18-12-4-2-1-3-5-12/h1-9,14H,10-11H2 LSONWRHLFZYHIN-UHFFFAOYSA-N 50264809 2-((4-phenoxyphenylsulfonyl)methyl)thiirane::CHEMBL483857::Thiirane (deuterium), 1-d2::Thiirane, 1::US10357546, SB-3CT Disintegrin and metalloproteinase domain-containing protein 17 3700 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264809&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9883002 104112685 CHEMBL483857 ZINC13916763 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432360 N[C@H]1CCCC[C@H]1NC(=O)P(O)(O)=O InChI=1S/C7H15N2O4P/c8-5-3-1-2-4-6(5)9-7(10)14(11,12)13/h5-6H,1-4,8H2,(H,9,10)(H2,11,12,13)/t5-,6+/m0/s1 XHCXISPZIHYKQD-NTSWFWBYSA-N 50234465 CHEMBL270083::cis-2-aminocyclohexylcarbamoylphosphonic acid Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50234465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50234465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44457233 104055923 CHEMBL270083 ZINC29134634 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432375 NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](Cc1cc(no1)-c1ccc(cc1)-c1cccc(Cl)c1)CP(O)(=O)c1ccc(Br)cc1 InChI=1S/C35H35BrClN4O10P/c36-24-8-10-27(11-9-24)52(49,50)19-23(34(47)40-29(13-15-32(44)45)35(48)39-28(33(38)46)12-14-31(42)43)17-26-18-30(41-51-26)21-6-4-20(5-7-21)22-2-1-3-25(37)16-22/h1-11,16,18,23,28-29H,12-15,17,19H2,(H2,38,46)(H,39,48)(H,40,47)(H,42,43)(H,44,45)(H,49,50)/t23-,28+,29+/m1/s1 PTUCPHGSAFOJAU-MGONOCMRSA-N 50265078 (4S)-5-amino-4-((2S)-2-((2S)-3-((4-bromophenyl)(hydroxy)phosphoryl)-2-((3-(3'-chlorobiphenyl-4-yl)isoxazol-5-yl)methyl)propanamido)-4-carboxybutanamido)-5-oxopentanoic acid::CHEMBL507420 Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265078 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265078&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search R47 5L7F,5L79,5CZM,4GQL 44580458 104112891 CHEMBL507420 ZINC95540503 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432390 COc1c(Br)ccc2oc(COc3ccc(cc3)-c3ccc(cc3)S(=O)(=O)N[C@H](C(C)C)C(O)=O)c(C)c12 InChI=1S/C28H28BrNO7S/c1-16(2)26(28(31)32)30-38(33,34)21-11-7-19(8-12-21)18-5-9-20(10-6-18)36-15-24-17(3)25-23(37-24)14-13-22(29)27(25)35-4/h5-14,16,26,30H,15H2,1-4H3,(H,31,32)/t26-/m1/s1 KQIFSUSWYMDFOC-AREMUKBSSA-N 50265076 (R)-2-(4'-((5-bromo-4-methoxy-3-methylbenzofuran-2-yl)methoxy)biphenyl-4-ylsulfonamido)-3-methylbutanoic acid::CHEMBL497772 Disintegrin and metalloproteinase domain-containing protein 17 >25000 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265076 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265076&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11342435 104112889 CHEMBL497772 ZINC14210485 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432486 CN1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCN(CC1)c1ccc(cn1)C(F)(F)F)C(=O)NO InChI=1S/C20H26F3N5O3/c1-26-12-19(4-5-19)10-14(17(29)25-31)16(26)18(30)28-8-6-27(7-9-28)15-3-2-13(11-24-15)20(21,22)23/h2-3,11,14,16,31H,4-10,12H2,1H3,(H,25,29)/t14-,16-/m0/s1 HJNKYGBTSGQBDU-HOCLYGCPSA-N 50265157 (6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carbonyl)-5-azaspiro[2.5]octane-7-carboxamide::CHEMBL497985 Disintegrin and metalloproteinase domain-containing protein 17 2045 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50265157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50265157&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580539 104112953 CHEMBL497985 ZINC40973623 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432487 COC(=O)N1CC2(CC2)C[C@@H]([C@H]1C(=O)N1CCC(=CC1)c1ccccc1)C(=O)NO InChI=1S/C22H27N3O5/c1-30-21(28)25-14-22(9-10-22)13-17(19(26)23-29)18(25)20(27)24-11-7-16(8-12-24)15-5-3-2-4-6-15/h2-7,17-18,29H,8-14H2,1H3,(H,23,26)/t17-,18-/m0/s1 CKZHFOKQZRZCPF-ROUUACIJSA-N 50203527 (6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate::CHEMBL434567::methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50203527 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50203527&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11625778 104082621 CHEMBL434567 ZINC13985960 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432520 COC(=O)[C@@]1(C[C@H]1C(=O)NO)c1cccc(OCc2cc(C)nc3ccccc23)c1 InChI=1S/C23H22N2O5/c1-14-10-15(18-8-3-4-9-20(18)24-14)13-30-17-7-5-6-16(11-17)23(22(27)29-2)12-19(23)21(26)25-28/h3-11,19,28H,12-13H2,1-2H3,(H,25,26)/t19-,23-/m0/s1 VQLUSPJMTIROIO-CVDCTZTESA-N 23454 CHEMBL270558::hydroxamate deriv., 26::methyl (1R,2R)-2-(hydroxycarbamoyl)-1-{3-[(2-methylquinolin-4-yl)methoxy]phenyl}cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23454 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23454&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24800654 50091716 CHEMBL270558 ZINC29134794 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432521 COC(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C24H24N2O5/c1-15-11-17(19-5-3-4-6-21(19)25-15)14-31-18-9-7-16(8-10-18)12-24(23(28)30-2)13-20(24)22(27)26-29/h3-11,20,29H,12-14H2,1-2H3,(H,26,27)/t20-,24+/m1/s1 HJWMYFBKJRVWJY-YKSBVNFPSA-N 23484 CHEMBL410462::hydroxamate deriv., 34::methyl (1R,2S)-2-(hydroxycarbamoyl)-1-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23484 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23484&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 550 3EDZ 24800833 50091746 CHEMBL410462 DB07147 ZINC29135377 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432522 CC#CCOc1ccc(cc1)S(=O)(=O)CCCS InChI=1S/C13H16O3S2/c1-2-3-9-16-12-5-7-13(8-6-12)18(14,15)11-4-10-17/h5-8,17H,4,9-11H2,1H3 CARKQNSZFCLNKM-UHFFFAOYSA-N 26554 3-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}propane-1-thiol::CHEMBL402747::thiol-aryl sulfone, 8b Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26554 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26554&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 440 3B92 23627203 56464991 CHEMBL402747 DB07079 ZINC24961483 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432528 CC(C)CN1CCC(CC1)=CC(CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)N(O)C=O InChI=1S/C30H37N3O5S/c1-22(2)18-32-14-12-24(13-15-32)17-26(33(35)21-34)20-39(36,37)28-10-8-27(9-11-28)38-19-25-16-23(3)31-30-7-5-4-6-29(25)30/h4-11,16-17,21-22,26,35H,12-15,18-20H2,1-3H3 ODPDWLUYVWCNHO-UHFFFAOYSA-N 50146472 CHEMBL318252::N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide::N-hydroxy-N-(1-(1-isobutylpiperidin-4-ylidene)-3-(4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)propan-2-yl)formamide Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330147 104035061 CHEMBL318252 ZINC14175331 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432536 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCCN(C1)C(=O)OCC(C)C)C(=O)NO InChI=1S/C22H30N2O7S/c1-4-5-13-30-18-7-9-19(10-8-18)32(28,29)16-22(20(25)23-27)11-6-12-24(15-22)21(26)31-14-17(2)3/h7-10,17,27H,6,11-16H2,1-3H3,(H,23,25) AGMWQNDXCWDRDZ-UHFFFAOYSA-N 50213944 CHEMBL399096::isobutyl 3-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-3-(hydroxycarbamoyl)piperidine-1-carboxylate Disintegrin and metalloproteinase domain-containing protein 17 3.2 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50213944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50213944&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44442305 104089163 CHEMBL399096 ZINC28951470 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432540 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H28N2O7S2/c1-4-5-14-29-17-6-8-18(9-7-17)30(25,26)15-20(19(23)21-24)10-12-22(13-11-20)31(27,28)16(2)3/h6-9,16,24H,10-15H2,1-3H3,(H,21,23) CEVLUPQNDFOYSI-UHFFFAOYSA-N 23500 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::CHEMBL209970::beta-sulfonyl hydroxamate analogue, 4 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23500&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11634234 50091761 CHEMBL209970 ZINC06718474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432546 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)c1c(C)noc1C)C(=O)NO InChI=1S/C22H27N3O6S/c1-4-5-14-30-18-6-8-19(9-7-18)32(28,29)15-22(21(26)23-27)10-12-25(13-11-22)20-16(2)24-31-17(20)3/h6-9,27H,10-15H2,1-3H3,(H,23,26) BBCCMNOZBPHYAJ-UHFFFAOYSA-N 50264815 4-((4-(but-2-ynyloxy)phenylsulfonyl)methyl)-1-(3,5-dimethylisoxazol-4-yl)-N-hydroxypiperidine-4-carboxamide::CHEMBL484262 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264815&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580184 104112691 CHEMBL484262 ZINC45483995 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50432553 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H]([C@H](C)O)C(=O)NO InChI=1S/C14H18N2O6S/c1-3-4-9-22-11-5-7-12(8-6-11)23(20,21)16-13(10(2)17)14(18)15-19/h5-8,10,13,16-17,19H,9H2,1-2H3,(H,15,18)/t10-,13+/m0/s1 VMOSDDURWLNMNG-GXFFZTMASA-N 50264814 (2R,3S)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-N,3-dihydroxybutanamide::CHEMBL484261 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmc.2008.08.058 10.7270/Q2JD4WM2 18790648 Georgiadis, D; Yiotakis, A University of Athens http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50264814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50264814&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15985818 104112690 CHEMBL484261 ZINC03817108 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50453174 CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C20H26N2O5S/c1-14(2)19(20(23)21-24)22(27-15(3)4)28(25,26)18-12-10-17(11-13-18)16-8-6-5-7-9-16/h5-15,19,24H,1-4H3,(H,21,23)/t19-/m1/s1 DGZZVIWCMGVHGV-LJQANCHMSA-N 50161330 (R)-2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-3-methyl-butyramide::(R)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3-methylbutanamide::CHEMBL179288 Disintegrin and metalloproteinase domain-containing protein 17 14000 ChEMBL 10.1016/j.ejmech.2015.11.019 10.7270/Q2HT2R63 26638045 Sjøli, S; Nuti, E; Camodeca, C; Bilto, I; Rossello, A; Winberg, JO; Sylte, I; Adekoya, OA UiT The Arctic University of Norway http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161330 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161330&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11292680 104047646 CHEMBL179288 ZINC13831240 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50453175 COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](C(C)C)C(=O)NO InChI=1S/C16H26N2O5S/c1-11(2)10-18(15(12(3)4)16(19)17-20)24(21,22)14-8-6-13(23-5)7-9-14/h6-9,11-12,15,20H,10H2,1-5H3,(H,17,19)/t15-/m1/s1 KLOYCYLPVRADHA-OAHLLOKOSA-N 50314228 (R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfonamido)-3-methylbutanamide::CHEMBL1090284 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1016/j.ejmech.2015.11.019 10.7270/Q2HT2R63 26638045 Sjøli, S; Nuti, E; Camodeca, C; Bilto, I; Rossello, A; Winberg, JO; Sylte, I; Adekoya, OA UiT The Arctic University of Norway http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314228&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45380189 104148589 CHEMBL1090284 ZINC49048822 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50453176 COc1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO InChI=1S/C15H15NO5S/c1-21-12-6-8-13(9-7-12)22(19,20)14-5-3-2-4-11(14)10-15(17)16-18/h2-9,18H,10H2,1H3,(H,16,17) ITWGWXCEGHFMHT-UHFFFAOYSA-N 50299053 CHEMBL573714::N-Hydroxy-2-(2-(4-methoxyphenylsulfonyl)phenyl)acetamide Disintegrin and metalloproteinase domain-containing protein 17 67000 ChEMBL 10.1016/j.ejmech.2015.11.019 10.7270/Q2HT2R63 26638045 Sjøli, S; Nuti, E; Camodeca, C; Bilto, I; Rossello, A; Winberg, JO; Sylte, I; Adekoya, OA UiT The Arctic University of Norway http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50299053 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50299053&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44478926 104140582 CHEMBL573714 ZINC45286734 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50453177 ONC(=O)Cc1ccccc1S(=O)(=O)c1ccc(OCCCN2C(=O)c3ccccc3C2=O)cc1 InChI=1S/C25H22N2O7S/c28-23(26-31)16-17-6-1-4-9-22(17)35(32,33)19-12-10-18(11-13-19)34-15-5-14-27-24(29)20-7-2-3-8-21(20)25(27)30/h1-4,6-13,31H,5,14-16H2,(H,26,28) ATZPVLVGDZFBHG-UHFFFAOYSA-N 50138796 CHEMBL3751971 Disintegrin and metalloproteinase domain-containing protein 17 150000 ChEMBL 10.1016/j.ejmech.2015.11.019 10.7270/Q2HT2R63 26638045 Sjøli, S; Nuti, E; Camodeca, C; Bilto, I; Rossello, A; Winberg, JO; Sylte, I; Adekoya, OA UiT The Arctic University of Norway http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138796&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11485450 104028819 CHEMBL3751971 ZINC27526631 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50453178 ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NC(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C25H21N3O6/c29-22(16-10-12-18(13-11-16)34-17-6-2-1-3-7-17)26-21(23(30)27-33)14-15-28-24(31)19-8-4-5-9-20(19)25(28)32/h1-13,21,33H,14-15H2,(H,26,29)(H,27,30)/t21-/m1/s1 HQCMGHWOKKWJEP-OAQYLSRUSA-N 50138797 CHEMBL3752374 Disintegrin and metalloproteinase domain-containing protein 17 9500 ChEMBL 10.1016/j.ejmech.2015.11.019 10.7270/Q2HT2R63 26638045 Sjøli, S; Nuti, E; Camodeca, C; Bilto, I; Rossello, A; Winberg, JO; Sylte, I; Adekoya, OA UiT The Arctic University of Norway http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138797&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11722988 104028820 CHEMBL3752374 ZINC13533267 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50453179 CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(Br)s1 InChI=1S/C9H13BrN2O5S2/c1-6(2)17-12(5-8(13)11-14)19(15,16)9-4-3-7(10)18-9/h3-4,6,14H,5H2,1-2H3,(H,11,13) GAQIUZBEKIRYHD-UHFFFAOYSA-N 50138798 CHEMBL3754100 Disintegrin and metalloproteinase domain-containing protein 17 114000 ChEMBL 10.1016/j.ejmech.2015.11.019 10.7270/Q2HT2R63 26638045 Sjøli, S; Nuti, E; Camodeca, C; Bilto, I; Rossello, A; Winberg, JO; Sylte, I; Adekoya, OA UiT The Arctic University of Norway http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50138798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50138798&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11277927 104028821 CHEMBL3754100 ZINC13533309 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50453180 CCCCC(NOCc1ccccc1)C(=O)NO InChI=1S/C13H20N2O3/c1-2-3-9-12(13(16)14-17)15-18-10-11-7-5-4-6-8-11/h4-8,12,15,17H,2-3,9-10H2,1H3,(H,14,16) MTXWGHZYBWXADO-UHFFFAOYSA-N 50204382 2-(benzyloxyamino)-N-hydroxyhexanamide::CHEMBL228230 Disintegrin and metalloproteinase domain-containing protein 17 100000 ChEMBL 10.1016/j.ejmech.2015.11.019 10.7270/Q2HT2R63 26638045 Sjøli, S; Nuti, E; Camodeca, C; Bilto, I; Rossello, A; Winberg, JO; Sylte, I; Adekoya, OA UiT The Arctic University of Norway http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204382 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204382&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44423686 104083082 CHEMBL228230 ZINC28647474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50457832 ONC(=O)\C=C\c1ccc(cc1)C(F)(F)F InChI=1S/C10H8F3NO2/c11-10(12,13)8-4-1-7(2-5-8)3-6-9(15)14-16/h1-6,16H,(H,14,15)/b6-3+ ABKAFUZUCJSIKV-ZZXKWVIFSA-N 50140176 CHEMBL3394285 Disintegrin and metalloproteinase domain-containing protein 17 21500 ChEMBL 10.1016/j.bmc.2015.12.035 10.7270/Q2Q52RG0 26753813 Ai, T; Qiu, L; Xie, J; Geraghty, RJ; Chen, L University of Minnesota http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50140176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50140176&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53374826 336952480 CHEMBL3394285 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459186 COc1cc(Cn2cc(C[C@@H](NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c3ccccc23)cc(OC)c1 InChI=1S/C30H30N2O7S/c1-4-5-14-39-23-10-12-26(13-11-23)40(35,36)31-28(30(33)34)17-22-20-32(29-9-7-6-8-27(22)29)19-21-15-24(37-2)18-25(16-21)38-3/h6-13,15-16,18,20,28,31H,14,17,19H2,1-3H3,(H,33,34)/t28-/m1/s1 RQJNXADKPTYING-MUUNZHRXSA-N 50278889 CHEMBL506243::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(3,5-dimethoxybenzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 980 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278889 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278889&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11606523 104121013 CHEMBL506243 ZINC42834856 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459187 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C21H20N2O5S/c1-2-3-12-28-16-8-10-17(11-9-16)29(26,27)23-20(21(24)25)13-15-14-22-19-7-5-4-6-18(15)19/h4-11,14,20,22-23H,12-13H2,1H3,(H,24,25)/t20-/m1/s1 XSNFXGZIUUWXFB-HXUWFJFHSA-N 50279221 CHEMBL498058::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 2530 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279221&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11704287 104121234 CHEMBL498058 ZINC38280031 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459188 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2ccc(C)cc12)C(O)=O InChI=1S/C22H22N2O5S/c1-3-4-11-29-17-6-8-18(9-7-17)30(27,28)24-21(22(25)26)13-16-14-23-20-10-5-15(2)12-19(16)20/h5-10,12,14,21,23-24H,11,13H2,1-2H3,(H,25,26) SFVPXERGVLDWIS-UHFFFAOYSA-N 50279255 2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methyl-1H-indol-3-yl)propanoic acid::CHEMBL497733::rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-methyl-1H-indol-3-yl)-propionic acid Disintegrin and metalloproteinase domain-containing protein 17 280 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279255 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279255&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 792 3G42 11676244 104121252 CHEMBL497733 ZINC38225899 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459189 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1c[nH]c2ccc(C)cc12)C(O)=O InChI=1S/C22H22N2O5S/c1-3-4-11-29-17-6-8-18(9-7-17)30(27,28)24-21(22(25)26)13-16-14-23-20-10-5-15(2)12-19(16)20/h5-10,12,14,21,23-24H,11,13H2,1-2H3,(H,25,26)/t21-/m1/s1 SFVPXERGVLDWIS-OAQYLSRUSA-N 50279256 CHEMBL527018::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methyl-1H-indol-3-yl)propanoic acid::N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan Disintegrin and metalloproteinase domain-containing protein 17 140 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279256 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279256&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 792 3G42 42627769 104121253 CHEMBL527018 DB07233 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459191 COc1ccc2[nH]cc(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C22H22N2O6S/c1-3-4-11-30-16-5-8-18(9-6-16)31(27,28)24-21(22(25)26)12-15-14-23-20-10-7-17(29-2)13-19(15)20/h5-10,13-14,21,23-24H,11-12H2,1-2H3,(H,25,26) QBMRYLHKTSDMJW-UHFFFAOYSA-N 50279257 2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-1H-indol-3-yl)propanoic acid::CHEMBL497908::rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-methoxy-1H-indol-3-yl)-propionic acid Disintegrin and metalloproteinase domain-containing protein 17 10100 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279257 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279257&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11510523 104121254 CHEMBL497908 ZINC40976006 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459195 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(O)=O InChI=1S/C28H26N2O6S/c1-2-3-15-35-22-9-12-24(13-10-22)37(33,34)30-27(28(31)32)16-21-18-29-26-14-11-23(17-25(21)26)36-19-20-7-5-4-6-8-20/h4-14,17-18,27,29-30H,15-16,19H2,1H3,(H,31,32) OPSGGAROSGLASJ-UHFFFAOYSA-N 50279287 3-(5-(benzyloxy)-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid::CHEMBL463395::rac-2-(4-But-2-ynyloxy-benzenesulfonyl-amino)-3-(5-benzyloxy-1H-indol-3-yl)-propionic acid Disintegrin and metalloproteinase domain-containing protein 17 6980 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279287&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11533683 104121271 CHEMBL463395 ZINC34621352 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459196 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2ccc(F)cc12)C(O)=O InChI=1S/C21H19FN2O5S/c1-2-3-10-29-16-5-7-17(8-6-16)30(27,28)24-20(21(25)26)11-14-13-23-19-9-4-15(22)12-18(14)19/h4-9,12-13,20,23-24H,10-11H2,1H3,(H,25,26) QOGALZKFHQFSHT-UHFFFAOYSA-N 50279341 CHEMBL520686::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-fluoro-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1560 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279341 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279341&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11575575 104121287 CHEMBL520686 ZINC35849377 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459197 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2ccc(O)cc12)C(O)=O InChI=1S/C21H20N2O6S/c1-2-3-10-29-16-5-7-17(8-6-16)30(27,28)23-20(21(25)26)11-14-13-22-19-9-4-15(24)12-18(14)19/h4-9,12-13,20,22-24H,10-11H2,1H3,(H,25,26) YXUJHGQKTDWIHA-UHFFFAOYSA-N 50279342 CHEMBL519909::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-hydroxy-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1610 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279342 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279342&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11560983 104121288 CHEMBL519909 ZINC35818728 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459198 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2ccc(Br)cc12)C(O)=O InChI=1S/C21H19BrN2O5S/c1-2-3-10-29-16-5-7-17(8-6-16)30(27,28)24-20(21(25)26)11-14-13-23-19-9-4-15(22)12-18(14)19/h4-9,12-13,20,23-24H,10-11H2,1H3,(H,25,26) KIWWTPJSIDMQDE-UHFFFAOYSA-N 50279343 CHEMBL487755::rac-3-(5-bromo-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 630 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279343 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279343&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11591268 104121289 CHEMBL487755 ZINC35880810 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459199 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2cc(F)ccc12)C(O)=O InChI=1S/C21H19FN2O5S/c1-2-3-10-29-16-5-7-17(8-6-16)30(27,28)24-20(21(25)26)11-14-13-23-19-12-15(22)4-9-18(14)19/h4-9,12-13,20,23-24H,10-11H2,1H3,(H,25,26) HJVUWJYDFMMKJE-UHFFFAOYSA-N 50279374 CHEMBL521238::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(6-fluoro-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 2960 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279374 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279374&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11502876 104121309 CHEMBL521238 ZINC42887389 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459200 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c[nH]c2cc(C)ccc12)C(O)=O InChI=1S/C22H22N2O5S/c1-3-4-11-29-17-6-8-18(9-7-17)30(27,28)24-21(22(25)26)13-16-14-23-20-12-15(2)5-10-19(16)20/h5-10,12,14,21,23-24H,11,13H2,1-2H3,(H,25,26) HWVQOMWKUMBVQT-UHFFFAOYSA-N 50279375 CHEMBL487138::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(6-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1570 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279375 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279375&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11697569 104121310 CHEMBL487138 ZINC38268908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459201 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(C(=O)OC(C)(C)C)c2ccccc12)C(O)=O InChI=1S/C26H28N2O7S/c1-5-6-15-34-19-11-13-20(14-12-19)36(32,33)27-22(24(29)30)16-18-17-28(25(31)35-26(2,3)4)23-10-8-7-9-21(18)23/h7-14,17,22,27H,15-16H2,1-4H3,(H,29,30)/t22-/m1/s1 DXEPONXIBPHOTN-JOCHJYFZSA-N 50279376 CHEMBL520548::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(tert-butoxycarbonyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 3670 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279376 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279376&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592980 104121311 CHEMBL520548 ZINC40422521 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459202 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(C)c2ccccc12)C(O)=O InChI=1S/C22H22N2O5S/c1-3-4-13-29-17-9-11-18(12-10-17)30(27,28)23-20(22(25)26)14-16-15-24(2)21-8-6-5-7-19(16)21/h5-12,15,20,23H,13-14H2,1-2H3,(H,25,26)/t20-/m1/s1 YKECBMVMVCFUOL-HXUWFJFHSA-N 50279377 CHEMBL487139::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1430 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279377 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279377&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11524708 104121312 CHEMBL487139 ZINC45495880 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459203 CCCCCn1cc(C[C@@H](NS(=O)(=O)c2ccc(OCC#CC)cc2)C(O)=O)c2ccccc12 InChI=1S/C26H30N2O5S/c1-3-5-9-16-28-19-20(23-10-7-8-11-25(23)28)18-24(26(29)30)27-34(31,32)22-14-12-21(13-15-22)33-17-6-4-2/h7-8,10-15,19,24,27H,3,5,9,16-18H2,1-2H3,(H,29,30)/t24-/m1/s1 PMDQNXBWBVMTMJ-XMMPIXPASA-N 50279412 CHEMBL484617::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-pentyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 2310 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279412 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279412&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11648703 104121337 CHEMBL484617 ZINC35999041 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459204 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(CC2CCC2)c2ccccc12)C(O)=O InChI=1S/C26H28N2O5S/c1-2-3-15-33-21-11-13-22(14-12-21)34(31,32)27-24(26(29)30)16-20-18-28(17-19-7-6-8-19)25-10-5-4-9-23(20)25/h4-5,9-14,18-19,24,27H,6-8,15-17H2,1H3,(H,29,30)/t24-/m1/s1 NTBLUXWHDIKMIO-XMMPIXPASA-N 50279413 CHEMBL520816::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(cyclobutylmethyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1710 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279413 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279413&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11554783 104121338 CHEMBL520816 ZINC35802315 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459205 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(CCCCOc2ccccc2)c2ccccc12)C(O)=O InChI=1S/C31H32N2O6S/c1-2-3-20-38-26-15-17-27(18-16-26)40(36,37)32-29(31(34)35)22-24-23-33(30-14-8-7-13-28(24)30)19-9-10-21-39-25-11-5-4-6-12-25/h4-8,11-18,23,29,32H,9-10,19-22H2,1H3,(H,34,35)/t29-/m1/s1 DKPDDCMZCBAZFB-GDLZYMKVSA-N 50279414 CHEMBL523616::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-phenoxybutyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1250 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279414 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279414&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11570382 104121339 CHEMBL523616 ZINC42889983 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459206 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2ccccc2)c2ccccc12)C(O)=O InChI=1S/C28H26N2O5S/c1-2-3-17-35-23-13-15-24(16-14-23)36(33,34)29-26(28(31)32)18-22-20-30(19-21-9-5-4-6-10-21)27-12-8-7-11-25(22)27/h4-16,20,26,29H,17-19H2,1H3,(H,31,32)/t26-/m1/s1 KSOITDQDVXPBED-AREMUKBSSA-N 50279415 CHEMBL483952::D-3-(1-benzyl-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 2150 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279415 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279415&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11576985 104121340 CHEMBL483952 ZINC35851023 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459207 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2ccccc2-c2ccccc2)c2ccccc12)C(O)=O InChI=1S/C34H30N2O5S/c1-2-3-21-41-28-17-19-29(20-18-28)42(39,40)35-32(34(37)38)22-27-24-36(33-16-10-9-15-31(27)33)23-26-13-7-8-14-30(26)25-11-5-4-6-12-25/h4-20,24,32,35H,21-23H2,1H3,(H,37,38)/t32-/m1/s1 VNFRGIVJIDRVIG-JGCGQSQUSA-N 50279416 CHEMBL452642::D-3-(1-(biphenyl-2-ylmethyl)-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 970 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279416 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279416&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11613968 104121341 CHEMBL452642 ZINC44307986 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459208 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2ccc(OCC=C)cc2)c2ccccc12)C(O)=O InChI=1S/C31H30N2O6S/c1-3-5-19-39-26-14-16-27(17-15-26)40(36,37)32-29(31(34)35)20-24-22-33(30-9-7-6-8-28(24)30)21-23-10-12-25(13-11-23)38-18-4-2/h4,6-17,22,29,32H,2,18-21H2,1H3,(H,34,35)/t29-/m1/s1 WJTLWRHMCRMRAJ-GDLZYMKVSA-N 50278888 CHEMBL526567::D-3-(1-(4-(allyloxy)benzyl)-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 540 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278888 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278888&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592563 104121012 CHEMBL526567 ZINC42921694 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459209 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C21H20N2O5S/c1-2-3-12-28-16-8-10-17(11-9-16)29(26,27)23-20(21(24)25)13-15-14-22-19-7-5-4-6-18(15)19/h4-11,14,20,22-23H,12-13H2,1H3,(H,24,25)/t20-/m0/s1 XSNFXGZIUUWXFB-FQEVSTJZSA-N 50279220 CHEMBL522567::L-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 8200 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279220&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11711300 104121233 CHEMBL522567 ZINC34636142 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459210 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2cccc(c2)C(F)(F)F)c2ccccc12)C(O)=O InChI=1S/C29H25F3N2O5S/c1-2-3-15-39-23-11-13-24(14-12-23)40(37,38)33-26(28(35)36)17-21-19-34(27-10-5-4-9-25(21)27)18-20-7-6-8-22(16-20)29(30,31)32/h4-14,16,19,26,33H,15,17-18H2,1H3,(H,35,36)/t26-/m1/s1 CPKGYSISBWMCAJ-AREMUKBSSA-N 50278913 CHEMBL502558::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(3-(trifluoromethyl)benzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 2300 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278913 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278913&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11563197 104121029 CHEMBL502558 ZINC42802812 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459211 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2ccc(cc2)C(F)(F)F)c2ccccc12)C(O)=O InChI=1S/C29H25F3N2O5S/c1-2-3-16-39-23-12-14-24(15-13-23)40(37,38)33-26(28(35)36)17-21-19-34(27-7-5-4-6-25(21)27)18-20-8-10-22(11-9-20)29(30,31)32/h4-15,19,26,33H,16-18H2,1H3,(H,35,36)/t26-/m1/s1 VFILZQFILMXELU-AREMUKBSSA-N 50278914 CHEMBL524726::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-(trifluoromethyl)benzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 4400 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278914 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278914&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11713901 104121030 CHEMBL524726 ZINC42891958 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459212 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2ccc(C)cc2)c2ccccc12)C(O)=O InChI=1S/C29H28N2O5S/c1-3-4-17-36-24-13-15-25(16-14-24)37(34,35)30-27(29(32)33)18-23-20-31(28-8-6-5-7-26(23)28)19-22-11-9-21(2)10-12-22/h5-16,20,27,30H,17-19H2,1-2H3,(H,32,33)/t27-/m1/s1 VLOCVPZJBFHFHN-HHHXNRCGSA-N 50278915 CHEMBL501213::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-methylbenzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 3590 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278915 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278915&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11634941 104121031 CHEMBL501213 ZINC35975175 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459213 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2ccc(F)cc2)c2ccccc12)C(O)=O InChI=1S/C28H25FN2O5S/c1-2-3-16-36-23-12-14-24(15-13-23)37(34,35)30-26(28(32)33)17-21-19-31(27-7-5-4-6-25(21)27)18-20-8-10-22(29)11-9-20/h4-15,19,26,30H,16-18H2,1H3,(H,32,33)/t26-/m1/s1 OJBSWIIISXMJGA-AREMUKBSSA-N 50278940 CHEMBL525428::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-fluorobenzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1900 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278940&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11584432 104121053 CHEMBL525428 ZINC35874119 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459214 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](Cc1cn(Cc2ccc(Cl)cc2)c2ccccc12)C(O)=O InChI=1S/C28H25ClN2O5S/c1-2-3-16-36-23-12-14-24(15-13-23)37(34,35)30-26(28(32)33)17-21-19-31(27-7-5-4-6-25(21)27)18-20-8-10-22(29)11-9-20/h4-15,19,26,30H,16-18H2,1H3,(H,32,33)/t26-/m1/s1 GBQPESKFSBHZST-AREMUKBSSA-N 50278941 CHEMBL524677::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-chlorobenzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 3450 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278941&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11713566 104121054 CHEMBL524677 ZINC42890502 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459215 COc1ccc(Cn2cc(C[C@@H](NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c3ccccc23)cc1 InChI=1S/C29H28N2O6S/c1-3-4-17-37-24-13-15-25(16-14-24)38(34,35)30-27(29(32)33)18-22-20-31(28-8-6-5-7-26(22)28)19-21-9-11-23(36-2)12-10-21/h5-16,20,27,30H,17-19H2,1-2H3,(H,32,33)/t27-/m1/s1 JUSNXCIZGYMOPC-HHHXNRCGSA-N 50278942 CHEMBL499905::D-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-methoxybenzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 80 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11599024 104121055 CHEMBL499905 ZINC42805048 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459216 COc1ccc(Cn2cc(C[C@H](NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c3ccccc23)cc1 InChI=1S/C29H28N2O6S/c1-3-4-17-37-24-13-15-25(16-14-24)38(34,35)30-27(29(32)33)18-22-20-31(28-8-6-5-7-26(22)28)19-21-9-11-23(36-2)12-10-21/h5-16,20,27,30H,17-19H2,1-2H3,(H,32,33)/t27-/m0/s1 JUSNXCIZGYMOPC-MHZLTWQESA-N 50278974 CHEMBL524470::L-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-methoxybenzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1180 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278974&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11533863 104121071 CHEMBL524470 ZINC42805043 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50460228 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/acs.jmedchem.5b01434 10.7270/Q20G3N0F 26653735 Ruminski, PG; Massa, M; Strohbach, J; Hanau, CE; Schmidt, M; Scholten, JA; Fletcher, TR; Hamper, BC; Carroll, JN; Shieh, HS; Caspers, N; Collins, B; Grapperhaus, M; Palmquist, KE; Collins, J; Baldus, JE; Hitchcock, J; Kleine, HP; Rogers, MD; McDonald, J; Munie, GE; Messing, DM; Portolan, S; Whiteley, LO; Sunyer, T; Schnute, ME Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459218 CCn1cc(CC(NS(=O)(=O)c2ccc(OCC#CC)cc2)C(O)=O)c2cc(ccc12)C(O)=O InChI=1S/C24H24N2O7S/c1-3-5-12-33-18-7-9-19(10-8-18)34(31,32)25-21(24(29)30)14-17-15-26(4-2)22-11-6-16(23(27)28)13-20(17)22/h6-11,13,15,21,25H,4,12,14H2,1-2H3,(H,27,28)(H,29,30) PUPDDLPRSSGEEM-UHFFFAOYSA-N 50278976 CHEMBL498054::rac-3-(2-(4-(but-2-ynyloxy)phenylsulfonamido)-2-carboxyethyl)-1-ethyl-1H-indole-5-carboxylic acid Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278976&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592662 104121073 CHEMBL498054 ZINC40975220 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459219 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1cn(Cc2ccccc2)c2ccc(cc12)C(O)=O)C(O)=O InChI=1S/C29H26N2O7S/c1-2-3-15-38-23-10-12-24(13-11-23)39(36,37)30-26(29(34)35)17-22-19-31(18-20-7-5-4-6-8-20)27-14-9-21(28(32)33)16-25(22)27/h4-14,16,19,26,30H,15,17-18H2,1H3,(H,32,33)(H,34,35) FDMVYRMJGAYBTO-UHFFFAOYSA-N 50278977 CHEMBL524915::rac-1-benzyl-3-(2-(4-(but-2-ynyloxy)phenylsulfonamido)-2-carboxyethyl)-1H-indole-5-carboxylic acid Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278977&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592663 104121074 CHEMBL524915 ZINC42920217 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459220 COc1ccc2n(CC(C)C)cc(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C26H30N2O6S/c1-5-6-13-34-20-7-10-22(11-8-20)35(31,32)27-24(26(29)30)14-19-17-28(16-18(2)3)25-12-9-21(33-4)15-23(19)25/h7-12,15,17-18,24,27H,13-14,16H2,1-4H3,(H,29,30) FFAABIRLPNWOLW-UHFFFAOYSA-N 50278995 CHEMBL497738::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-isobutyl-5-methoxy-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1230 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278995&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11627426 104121086 CHEMBL497738 ZINC35953235 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459221 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c(C)n(CC(C)C)c2ccc(Cl)cc12)C(O)=O InChI=1S/C26H29ClN2O5S/c1-5-6-13-34-20-8-10-21(11-9-20)35(32,33)28-24(26(30)31)15-22-18(4)29(16-17(2)3)25-12-7-19(27)14-23(22)25/h7-12,14,17,24,28H,13,15-16H2,1-4H3,(H,30,31) VVWFDBJOCZQDLN-UHFFFAOYSA-N 50278996 CHEMBL497904::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-chloro-1-isobutyl-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 300 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278996&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592694 104121087 CHEMBL497904 ZINC40975735 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459222 COc1ccc(Cn2cc(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c3cc(C)ccc23)cc1 InChI=1S/C30H30N2O6S/c1-4-5-16-38-25-11-13-26(14-12-25)39(35,36)31-28(30(33)34)18-23-20-32(29-15-6-21(2)17-27(23)29)19-22-7-9-24(37-3)10-8-22/h6-15,17,20,28,31H,16,18-19H2,1-3H3,(H,33,34) JOOINNOCBRICQS-UHFFFAOYSA-N 50278997 CHEMBL525641::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-methoxybenzyl)-5-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 890 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278997&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11497618 104121088 CHEMBL525641 ZINC42921674 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459223 COc1ccc(Cn2c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c3cc(Cl)ccc23)cc1 InChI=1S/C30H29ClN2O6S/c1-4-5-16-39-24-11-13-25(14-12-24)40(36,37)32-28(30(34)35)18-26-20(2)33(29-15-8-22(31)17-27(26)29)19-21-6-9-23(38-3)10-7-21/h6-15,17,28,32H,16,18-19H2,1-3H3,(H,34,35) LBLFMINKFHCTCP-UHFFFAOYSA-N 50278998 CHEMBL504926::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-chloro-1-(4-methoxybenzyl)-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 190 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278998&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592695 104121089 CHEMBL504926 ZINC42834106 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459224 COc1ccc2n(C)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C24H26N2O6S/c1-5-6-13-32-17-7-10-19(11-8-17)33(29,30)25-22(24(27)28)15-20-16(2)26(3)23-12-9-18(31-4)14-21(20)23/h7-12,14,22,25H,13,15H2,1-4H3,(H,27,28) YRFZCPGAWONMLD-UHFFFAOYSA-N 50279025 CHEMBL525730::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-1,2-dimethyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 900 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279025&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592730 104121104 CHEMBL525730 ZINC40973633 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459225 COc1ccc2n(Cc3ccccc3)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C30H30N2O6S/c1-4-5-17-38-23-11-14-25(15-12-23)39(35,36)31-28(30(33)34)19-26-21(2)32(20-22-9-7-6-8-10-22)29-16-13-24(37-3)18-27(26)29/h6-16,18,28,31H,17,19-20H2,1-3H3,(H,33,34) NBDNTRPQGNCRGY-UHFFFAOYSA-N 50279026 CHEMBL505719::rac-3-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 250 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279026&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592731 104121105 CHEMBL505719 ZINC42834831 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459226 COc1ccc2n(Cc3ccc4OCOc4c3)cc(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C30H28N2O8S/c1-3-4-13-38-22-6-9-24(10-7-22)41(35,36)31-26(30(33)34)15-21-18-32(27-11-8-23(37-2)16-25(21)27)17-20-5-12-28-29(14-20)40-19-39-28/h5-12,14,16,18,26,31H,13,15,17,19H2,1-2H3,(H,33,34) BKPJMHCCRFBEKQ-UHFFFAOYSA-N 50279027 CHEMBL449262::rac-3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)-5-methoxy-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 1500 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279027&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11664224 104121106 CHEMBL449262 ZINC44352136 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459227 COc1ccc2n(Cc3ccc4OCOc4c3)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C31H30N2O8S/c1-4-5-14-39-22-7-10-24(11-8-22)42(36,37)32-27(31(34)35)17-25-20(2)33(28-12-9-23(38-3)16-26(25)28)18-21-6-13-29-30(15-21)41-19-40-29/h6-13,15-16,27,32H,14,17-19H2,1-3H3,(H,34,35) QMJAKLBJRYFPPQ-UHFFFAOYSA-N 50279028 CHEMBL503835::rac-3-(1-(benzo[d][1,3]dioxol-5-ylmethyl)-5-methoxy-2-methyl-1H-indol-3-yl)-2-(4-(but-2-ynyloxy)phenylsulfonamido)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 330 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279028&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592732 104121107 CHEMBL503835 ZINC42806079 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459228 COc1cccc(Cn2cc(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c3cc(OC)ccc23)c1 InChI=1S/C30H30N2O7S/c1-4-5-15-39-23-9-12-26(13-10-23)40(35,36)31-28(30(33)34)17-22-20-32(19-21-7-6-8-24(16-21)37-2)29-14-11-25(38-3)18-27(22)29/h6-14,16,18,20,28,31H,15,17,19H2,1-3H3,(H,33,34) CGWGVPGFBAWOQY-UHFFFAOYSA-N 50279029 CHEMBL526385::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-1-(3-methoxybenzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 2240 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279029 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279029&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11671315 104121108 CHEMBL526385 ZINC42919989 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459229 COc1cccc(Cn2c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c3cc(OC)ccc23)c1 InChI=1S/C31H32N2O7S/c1-5-6-16-40-23-10-13-26(14-11-23)41(36,37)32-29(31(34)35)19-27-21(2)33(20-22-8-7-9-24(17-22)38-3)30-15-12-25(39-4)18-28(27)30/h7-15,17-18,29,32H,16,19-20H2,1-4H3,(H,34,35) XTVMSWRVEWKOHL-UHFFFAOYSA-N 50279067 CHEMBL507022::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-1-(3-methoxybenzyl)-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 280 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279067 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279067&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592766 104121133 CHEMBL507022 ZINC42833907 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459230 COc1ccc2n(Cc3ccccc3OC(F)(F)F)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C31H29F3N2O7S/c1-4-5-16-42-22-10-13-24(14-11-22)44(39,40)35-27(30(37)38)18-25-20(2)36(28-15-12-23(41-3)17-26(25)28)19-21-8-6-7-9-29(21)43-31(32,33)34/h6-15,17,27,35H,16,18-19H2,1-3H3,(H,37,38) LDNJHRPKWVKTTE-UHFFFAOYSA-N 50279068 CHEMBL504122::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-2-methyl-1-(2-(trifluoromethoxy)benzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 500 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279068 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279068&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592767 104121134 CHEMBL504122 ZINC49898853 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459231 COc1ccc2n(Cc3ccc(OC(F)(F)F)cc3)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C31H29F3N2O7S/c1-4-5-16-42-22-10-13-25(14-11-22)44(39,40)35-28(30(37)38)18-26-20(2)36(29-15-12-24(41-3)17-27(26)29)19-21-6-8-23(9-7-21)43-31(32,33)34/h6-15,17,28,35H,16,18-19H2,1-3H3,(H,37,38) MPXXKNZEBNNEBF-UHFFFAOYSA-N 50279069 CHEMBL449253::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-methoxy-2-methyl-1-(4-(trifluoromethoxy)benzyl)-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 490 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279069 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279069&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592768 104121135 CHEMBL449253 ZINC49833358 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459232 COc1ccc2n(Cc3ccccc3F)cc(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C29H27FN2O6S/c1-3-4-15-38-22-9-12-24(13-10-22)39(35,36)31-27(29(33)34)16-21-19-32(18-20-7-5-6-8-26(20)30)28-14-11-23(37-2)17-25(21)28/h5-14,17,19,27,31H,15-16,18H2,1-2H3,(H,33,34) PYARQCOYZBKPJJ-UHFFFAOYSA-N 50279070 CHEMBL507280::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(2-fluorobenzyl)-5-methoxy-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 2240 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279070 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279070&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11606412 104121136 CHEMBL507280 ZINC42834753 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459233 COc1ccc2n(Cc3ccccc3F)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C30H29FN2O6S/c1-4-5-16-39-22-10-13-24(14-11-22)40(36,37)32-28(30(34)35)18-25-20(2)33(19-21-8-6-7-9-27(21)31)29-15-12-23(38-3)17-26(25)29/h6-15,17,28,32H,16,18-19H2,1-3H3,(H,34,35) APFLXVBPXMYYLG-UHFFFAOYSA-N 50279071 CHEMBL503326::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(2-fluorobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 300 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279071 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279071&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592769 104121137 CHEMBL503326 ZINC42804632 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459234 COc1ccc2n(Cc3cccc(F)c3)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C30H29FN2O6S/c1-4-5-15-39-23-9-12-25(13-10-23)40(36,37)32-28(30(34)35)18-26-20(2)33(19-21-7-6-8-22(31)16-21)29-14-11-24(38-3)17-27(26)29/h6-14,16-17,28,32H,15,18-19H2,1-3H3,(H,34,35) DVRWBQFNAUILCN-UHFFFAOYSA-N 50279108 CHEMBL499633::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(3-fluorobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 340 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279108&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592791 104121166 CHEMBL499633 ZINC49888961 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459235 COc1ccc2n(Cc3ccc(F)cc3)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C30H29FN2O6S/c1-4-5-16-39-23-10-13-25(14-11-23)40(36,37)32-28(30(34)35)18-26-20(2)33(19-21-6-8-22(31)9-7-21)29-15-12-24(38-3)17-27(26)29/h6-15,17,28,32H,16,18-19H2,1-3H3,(H,34,35) IAIXLTWVQYIOSK-UHFFFAOYSA-N 50279109 CHEMBL524912::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-fluorobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 320 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279109&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592792 104121167 CHEMBL524912 ZINC42920125 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459236 COc1ccc2n(Cc3ccc(Cl)cc3)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C30H29ClN2O6S/c1-4-5-16-39-23-10-13-25(14-11-23)40(36,37)32-28(30(34)35)18-26-20(2)33(19-21-6-8-22(31)9-7-21)29-15-12-24(38-3)17-27(26)29/h6-15,17,28,32H,16,18-19H2,1-3H3,(H,34,35) JKKLEYFTRWCQCH-UHFFFAOYSA-N 50279110 CHEMBL498806::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-chlorobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 290 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279110 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279110&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592793 104121168 CHEMBL498806 ZINC49888667 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459237 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1c(C)n(Cc2ccc(Cl)cc2)c2ccc(Cl)cc12)C(O)=O InChI=1S/C29H26Cl2N2O5S/c1-3-4-15-38-23-10-12-24(13-11-23)39(36,37)32-27(29(34)35)17-25-19(2)33(18-20-5-7-21(30)8-6-20)28-14-9-22(31)16-26(25)28/h5-14,16,27,32H,15,17-18H2,1-2H3,(H,34,35) MQFIRLCFJDRXSP-UHFFFAOYSA-N 50279152 CHEMBL525434::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(5-chloro-1-(4-chlorobenzyl)-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 330 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279152&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592834 104121189 CHEMBL525434 ZINC42921304 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459238 COc1ccc2n(Cc3cccc(c3)C#N)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C31H29N3O6S/c1-4-5-15-40-24-9-12-26(13-10-24)41(37,38)33-29(31(35)36)18-27-21(2)34(20-23-8-6-7-22(16-23)19-32)30-14-11-25(39-3)17-28(27)30/h6-14,16-17,29,33H,15,18,20H2,1-3H3,(H,35,36) XEZQMDSCWDKLHC-UHFFFAOYSA-N 50279153 2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(3-cyanobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)propanoic acid::CHEMBL501219 Disintegrin and metalloproteinase domain-containing protein 17 410 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279153&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592835 104121190 CHEMBL501219 ZINC42805160 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459239 COc1ccc2n(Cc3ccc(cc3)C#N)c(C)c(CC(NS(=O)(=O)c3ccc(OCC#CC)cc3)C(O)=O)c2c1 InChI=1S/C31H29N3O6S/c1-4-5-16-40-24-10-13-26(14-11-24)41(37,38)33-29(31(35)36)18-27-21(2)34(20-23-8-6-22(19-32)7-9-23)30-15-12-25(39-3)17-28(27)30/h6-15,17,29,33H,16,18,20H2,1-3H3,(H,35,36) VTHDJDRCGVYUMW-UHFFFAOYSA-N 50279154 CHEMBL500691::rac-2-(4-(but-2-ynyloxy)phenylsulfonamido)-3-(1-(4-cyanobenzyl)-5-methoxy-2-methyl-1H-indol-3-yl)propanoic acid Disintegrin and metalloproteinase domain-containing protein 17 470 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50279154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50279154&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592836 104121191 CHEMBL500691 ZINC42808428 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50459217 CC#CCOc1ccc(cc1)S(=O)(=O)NC(Cc1cn(C)c2ccc(cc12)C(O)=O)C(O)=O InChI=1S/C23H22N2O7S/c1-3-4-11-32-17-6-8-18(9-7-17)33(30,31)24-20(23(28)29)13-16-14-25(2)21-10-5-15(22(26)27)12-19(16)21/h5-10,12,14,20,24H,11,13H2,1-2H3,(H,26,27)(H,28,29) YKQLDTNXNSDOAE-UHFFFAOYSA-N 50278975 CHEMBL496859::rac-3-(2-(4-(but-2-ynyloxy)phenylsulfonamido)-2-carboxyethyl)-1-methyl-1H-indole-5-carboxylic acid Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1016/j.bmc.2009.04.033 10.7270/Q2DR2VCZ 19410464 Park, K; Gopalsamy, A; Aplasca, A; Ellingboe, JW; Xu, W; Zhang, Y; Levin, JI Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44592661 104121072 CHEMBL496859 ZINC40424250 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473937 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 100 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473938 Cc1cc(ccc1N1CCN(CC1)S(=O)(=O)N[C@H](CCCNC(=O)OCc1ccccc1)C(=O)NO)C#N InChI=1S/C25H32N6O6S/c1-19-16-21(17-26)9-10-23(19)30-12-14-31(15-13-30)38(35,36)29-22(24(32)28-34)8-5-11-27-25(33)37-18-20-6-3-2-4-7-20/h2-4,6-7,9-10,16,22,29,34H,5,8,11-15,18H2,1H3,(H,27,33)(H,28,32)/t22-/m1/s1 FWILDXURZVZYSC-JOCHJYFZSA-N 50151244 CHEMBL3770688 Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151244&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11465285 85603592 CHEMBL3770688 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473939 Cc1cc(ccc1N1CCN(CC1)S(=O)(=O)N1CSC[C@@H]1C(=O)NO)C#N InChI=1S/C16H21N5O4S2/c1-12-8-13(9-17)2-3-14(12)19-4-6-20(7-5-19)27(24,25)21-11-26-10-15(21)16(22)18-23/h2-3,8,15,23H,4-7,10-11H2,1H3,(H,18,22)/t15-/m1/s1 UGVOWFLXYXPRQV-OAHLLOKOSA-N 50151246 CHEMBL3770935 Disintegrin and metalloproteinase domain-containing protein 17 12000 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151246&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search LTQ 5CUH 11349448 85603751 CHEMBL3770935 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473940 CNC(=O)[C@@H](NC(=O)[C@H](CCCc1ccccc1)[C@H](C)N(O)C=O)C(C)(C)C InChI=1S/C21H33N3O4/c1-15(24(28)14-25)17(13-9-12-16-10-7-6-8-11-16)19(26)23-18(20(27)22-5)21(2,3)4/h6-8,10-11,14-15,17-18,28H,9,12-13H2,1-5H3,(H,22,27)(H,23,26)/t15-,17+,18+/m0/s1 GHVMTHKJUAOZJP-CGTJXYLNSA-N 50151245 CHEMBL1229516 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151245&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 023 2WO9,2WO8,2WOA 11440920 85603355 CHEMBL1229516 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473885 Cc1cc(ccc1N1CCN(CC1)S(=O)(=O)N[C@H](CCCNC(=O)OCc1ccccc1)C(=O)NO)C#N InChI=1S/C25H32N6O6S/c1-19-16-21(17-26)9-10-23(19)30-12-14-31(15-13-30)38(35,36)29-22(24(32)28-34)8-5-11-27-25(33)37-18-20-6-3-2-4-7-20/h2-4,6-7,9-10,16,22,29,34H,5,8,11-15,18H2,1H3,(H,27,33)(H,28,32)/t22-/m1/s1 FWILDXURZVZYSC-JOCHJYFZSA-N 50151244 CHEMBL3770688 Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151244&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11465285 85603592 CHEMBL3770688 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473886 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 500 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473915 CNC(=O)[C@@H](NC(=O)[C@H](CCCc1ccccc1)[C@H](C)N(O)C=O)C(C)(C)C InChI=1S/C21H33N3O4/c1-15(24(28)14-25)17(13-9-12-16-10-7-6-8-11-16)19(26)23-18(20(27)22-5)21(2,3)4/h6-8,10-11,14-15,17-18,28H,9,12-13H2,1-5H3,(H,22,27)(H,23,26)/t15-,17+,18+/m0/s1 GHVMTHKJUAOZJP-CGTJXYLNSA-N 50151245 CHEMBL1229516 Disintegrin and metalloproteinase domain-containing protein 17 860 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151245&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 023 2WO9,2WO8,2WOA 11440920 85603355 CHEMBL1229516 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473916 Cc1cc(ccc1N1CCN(CC1)S(=O)(=O)N1CSC[C@@H]1C(=O)NO)C#N InChI=1S/C16H21N5O4S2/c1-12-8-13(9-17)2-3-14(12)19-4-6-20(7-5-19)27(24,25)21-11-26-10-15(21)16(22)18-23/h2-3,8,15,23H,4-7,10-11H2,1H3,(H,18,22)/t15-/m1/s1 UGVOWFLXYXPRQV-OAHLLOKOSA-N 50151246 CHEMBL3770935 Disintegrin and metalloproteinase domain-containing protein 17 1500 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151246&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search LTQ 5CUH 11349448 85603751 CHEMBL3770935 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473917 Cc1cc(ccc1N1CCN(CC1)S(=O)(=O)N[C@H](CCCNC(=O)OCc1ccccc1)C(=O)NO)C#N InChI=1S/C25H32N6O6S/c1-19-16-21(17-26)9-10-23(19)30-12-14-31(15-13-30)38(35,36)29-22(24(32)28-34)8-5-11-27-25(33)37-18-20-6-3-2-4-7-20/h2-4,6-7,9-10,16,22,29,34H,5,8,11-15,18H2,1H3,(H,27,33)(H,28,32)/t22-/m1/s1 FWILDXURZVZYSC-JOCHJYFZSA-N 50151244 CHEMBL3770688 Disintegrin and metalloproteinase domain-containing protein 17 90 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151244 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151244&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11465285 85603592 CHEMBL3770688 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473918 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473923 Cc1cc(ccc1N1CCN(CC1)S(=O)(=O)N1CSC[C@@H]1C(=O)NO)C#N InChI=1S/C16H21N5O4S2/c1-12-8-13(9-17)2-3-14(12)19-4-6-20(7-5-19)27(24,25)21-11-26-10-15(21)16(22)18-23/h2-3,8,15,23H,4-7,10-11H2,1H3,(H,18,22)/t15-/m1/s1 UGVOWFLXYXPRQV-OAHLLOKOSA-N 50151246 CHEMBL3770935 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151246&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search LTQ 5CUH 11349448 85603751 CHEMBL3770935 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50473924 CNC(=O)[C@@H](NC(=O)[C@H](CCCc1ccccc1)[C@H](C)N(O)C=O)C(C)(C)C InChI=1S/C21H33N3O4/c1-15(24(28)14-25)17(13-9-12-16-10-7-6-8-11-16)19(26)23-18(20(27)22-5)21(2,3)4/h6-8,10-11,14-15,17-18,28H,9,12-13H2,1-5H3,(H,22,27)(H,23,26)/t15-,17+,18+/m0/s1 GHVMTHKJUAOZJP-CGTJXYLNSA-N 50151245 CHEMBL1229516 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1016/j.ejmech.2016.01.053 10.7270/Q2765H73 26871660 Camodeca, C; Nuti, E; Tepshi, L; Boero, S; Tuccinardi, T; Stura, EA; Poggi, A; Zocchi, MR; Rossello, A San Raffaele Scientific Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50151245 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50151245&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 023 2WO9,2WO8,2WOA 11440920 85603355 CHEMBL1229516 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204788 CCc1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC[C@@H]1C(=O)NO InChI=1S/C21H26N2O6S/c1-2-15-5-3-4-6-16(15)14-29-18-8-10-19(11-9-18)30(27,28)23-13-17(24)7-12-20(23)21(25)22-26/h3-6,8-11,17,20,24,26H,2,7,12-14H2,1H3,(H,22,25)/t17-,20-/m1/s1 XXUCOZXCPFTGGY-YLJYHZDGSA-N 50113045 (2R,5R)-1-[4-(2-Ethyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29069 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113045&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278396 104007396 CHEMBL29069 ZINC03820648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204791 CC(C)c1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC[C@@H]1C(=O)NO InChI=1S/C22H28N2O6S/c1-15(2)20-6-4-3-5-16(20)14-30-18-8-10-19(11-9-18)31(28,29)24-13-17(25)7-12-21(24)22(26)23-27/h3-6,8-11,15,17,21,25,27H,7,12-14H2,1-2H3,(H,23,26)/t17-,21-/m1/s1 XMCYAYXTCCGUCU-DYESRHJHSA-N 50113039 (2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29068 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113039&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278395 104007390 CHEMBL29068 ZINC13441650 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204795 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1 InChI=1S/C19H21FN2O6S/c20-14-3-1-13(2-4-14)12-28-16-5-7-17(8-6-16)29(26,27)22-10-9-15(23)11-18(22)19(24)21-25/h1-8,15,18,23,25H,9-12H2,(H,21,24)/t15-,18+/m0/s1 FCLQINRREQAAHO-MAUKXSAKSA-N 50113024 (2R,4S)-1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL285591 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113024&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9867022 104007375 CHEMBL285591 ZINC13441607 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204803 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccc(cc2)C#N)cc1 InChI=1S/C20H21N3O6S/c21-12-14-1-3-15(4-2-14)13-29-17-5-7-18(8-6-17)30(27,28)23-10-9-16(24)11-19(23)20(25)22-26/h1-8,16,19,24,26H,9-11,13H2,(H,22,25)/t16-,19+/m0/s1 CLPSJCJXXQNCHD-QFBILLFUSA-N 50113042 (2R,4S)-1-[4-(4-Cyano-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL414597 Disintegrin and metalloproteinase domain-containing protein 17 25 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113042&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278532 104007393 CHEMBL414597 ZINC13441630 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204811 Cc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CC[C@H](O)C[C@@H]1C(=O)NO InChI=1S/C20H24N2O6S/c1-14-4-2-3-5-15(14)13-28-17-6-8-18(9-7-17)29(26,27)22-11-10-16(23)12-19(22)20(24)21-25/h2-9,16,19,23,25H,10-13H2,1H3,(H,21,24)/t16-,19+/m0/s1 KZFRIHIZMZYZCN-QFBILLFUSA-N 50113028 (2R,4S)-4-Hydroxy-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28358 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113028&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541747 104007379 CHEMBL28358 ZINC13441623 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204813 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H22N2O6S/c22-15-6-11-18(19(23)20-24)21(12-15)28(25,26)17-9-7-16(8-10-17)27-13-14-4-2-1-3-5-14/h1-5,7-10,15,18,22,24H,6,11-13H2,(H,20,23)/t15-,18-/m1/s1 GIGWICZCQGBJDH-CRAIPNDOSA-N 50113048 (2R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29007 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113048&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278484 104007399 CHEMBL29007 ZINC13441636 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204819 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2Cl)cc1 InChI=1S/C19H21ClN2O6S/c20-17-4-2-1-3-13(17)12-28-15-5-7-16(8-6-15)29(26,27)22-10-9-14(23)11-18(22)19(24)21-25/h1-8,14,18,23,25H,9-12H2,(H,21,24)/t14-,18+/m0/s1 RIYWMJMELHHCTR-KBXCAEBGSA-N 50113022 (2R,4S)-1-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28646 Disintegrin and metalloproteinase domain-containing protein 17 36 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113022&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9932958 104007373 CHEMBL28646 ZINC13441617 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204822 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccc(Cl)cc2)cc1 InChI=1S/C19H21ClN2O6S/c20-14-3-1-13(2-4-14)12-28-16-5-7-17(8-6-16)29(26,27)22-10-9-15(23)11-18(22)19(24)21-25/h1-8,15,18,23,25H,9-12H2,(H,21,24)/t15-,18+/m0/s1 QYSRKEKGXZIJBG-MAUKXSAKSA-N 50113035 (2R,4S)-1-[4-(4-Chloro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL31776 Disintegrin and metalloproteinase domain-containing protein 17 58000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113035 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113035&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541746 104007386 CHEMBL31776 ZINC13441613 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204823 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2C#N)cc1 InChI=1S/C20H21N3O6S/c21-11-14-3-1-2-4-15(14)13-29-17-6-8-18(9-7-17)30(27,28)23-12-16(24)5-10-19(23)20(25)22-26/h1-4,6-9,16,19,24,26H,5,10,12-13H2,(H,22,25)/t16-,19-/m1/s1 PBIRCNBIZATFIL-VQIMIIECSA-N 50113031 (2R,5R)-1-[4-(2-Cyano-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28139 Disintegrin and metalloproteinase domain-containing protein 17 42000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113031 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113031&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9802812 104007382 CHEMBL28139 ZINC13441646 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204825 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2-c2ccccc2)cc1 InChI=1S/C25H26N2O6S/c28-20-14-15-27(24(16-20)25(29)26-30)34(31,32)22-12-10-21(11-13-22)33-17-19-8-4-5-9-23(19)18-6-2-1-3-7-18/h1-13,20,24,28,30H,14-17H2,(H,26,29)/t20-,24+/m0/s1 HLNRKJGRBAIQKZ-GBXCKJPGSA-N 50113020 (2R,4S)-1-[4-(Biphenyl-2-ylmethoxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL282094 Disintegrin and metalloproteinase domain-containing protein 17 >33000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113020&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278511 104007371 CHEMBL282094 ZINC13441634 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50204838 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc(c2)C#N)cc1 InChI=1S/C20H21N3O6S/c21-11-14-2-1-3-15(10-14)13-29-17-5-7-18(8-6-17)30(27,28)23-12-16(24)4-9-19(23)20(25)22-26/h1-3,5-8,10,16,19,24,26H,4,9,12-13H2,(H,22,25)/t16-,19-/m1/s1 VODMHORGCWILKX-VQIMIIECSA-N 50113026 (2R,5R)-1-[4-(3-Cyano-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28678 Disintegrin and metalloproteinase domain-containing protein 17 63000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113026&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278455 104007377 CHEMBL28678 ZINC13441644 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584807 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)17-4-2-1-3-13(17)12-31-15-6-8-16(9-7-15)32(29,30)25-11-14(26)5-10-18(25)19(27)24-28/h1-4,6-9,14,18,26,28H,5,10-12H2,(H,24,27)/t14-,18-/m1/s1 TVRQFUFQUOUOJG-RDTXWAMCSA-N 50113041 (2R,5R)-5-Hydroxy-1-[4-(2-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL27965 Disintegrin and metalloproteinase domain-containing protein 17 4000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113041 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113041&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9891048 104007392 CHEMBL27965 ZINC13441642 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584808 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(c2)C#N)cc1 InChI=1S/C20H21N3O6S/c21-12-14-2-1-3-15(10-14)13-29-17-4-6-18(7-5-17)30(27,28)23-9-8-16(24)11-19(23)20(25)22-26/h1-7,10,16,19,24,26H,8-9,11,13H2,(H,22,25)/t16-,19+/m0/s1 ZPGDUPIWHDBXOW-QFBILLFUSA-N 50113021 (2R,4S)-1-[4-(3-Cyano-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29217 Disintegrin and metalloproteinase domain-containing protein 17 33000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278512 104007372 CHEMBL29217 ZINC13441632 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584809 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccc(cc2)C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)14-3-1-13(2-4-14)12-31-16-6-8-17(9-7-16)32(29,30)25-11-15(26)5-10-18(25)19(27)24-28/h1-4,6-9,15,18,26,28H,5,10-12H2,(H,24,27)/t15-,18-/m1/s1 DLEQDRFQHDSZFK-CRAIPNDOSA-N 50113037 (2R,5R)-5-Hydroxy-1-[4-(4-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL282584 Disintegrin and metalloproteinase domain-containing protein 17 28000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113037 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113037&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278523 104007388 CHEMBL282584 ZINC13441638 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584810 Cc1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC[C@@H]1C(=O)NO InChI=1S/C20H24N2O6S/c1-14-4-2-3-5-15(14)13-28-17-7-9-18(10-8-17)29(26,27)22-12-16(23)6-11-19(22)20(24)21-25/h2-5,7-10,16,19,23,25H,6,11-13H2,1H3,(H,21,24)/t16-,19-/m1/s1 RADBGCOAJQAKKE-VQIMIIECSA-N 50113044 (2R,5R)-5-Hydroxy-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL31294 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113044&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278449 104007395 CHEMBL31294 ZINC13441648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584811 COc1cccc(COc2ccc(cc2)S(=O)(=O)N2CC[C@H](O)C[C@@H]2C(=O)NO)c1 InChI=1S/C20H24N2O7S/c1-28-17-4-2-3-14(11-17)13-29-16-5-7-18(8-6-16)30(26,27)22-10-9-15(23)12-19(22)20(24)21-25/h2-8,11,15,19,23,25H,9-10,12-13H2,1H3,(H,21,24)/t15-,19+/m0/s1 HESLKHVXAOLKPX-HNAYVOBHSA-N 50113036 (2R,4S)-4-Hydroxy-1-[4-(3-methoxy-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29211 Disintegrin and metalloproteinase domain-containing protein 17 >30000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113036 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113036&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278550 104007387 CHEMBL29211 ZINC13441625 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584812 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc3ccccc23)cc1 InChI=1S/C23H24N2O6S/c26-18-8-13-22(23(27)24-28)25(14-18)32(29,30)20-11-9-19(10-12-20)31-15-17-6-3-5-16-4-1-2-7-21(16)17/h1-7,9-12,18,22,26,28H,8,13-15H2,(H,24,27)/t18-,22-/m1/s1 FYZJGFHMVNBOIV-XMSQKQJNSA-N 50113025 (2R,5R)-5-Hydroxy-1-[4-(naphthalen-1-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL31315 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113025&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9955696 104007376 CHEMBL31315 ZINC13441652 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584813 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)17-4-2-1-3-13(17)12-31-15-5-7-16(8-6-15)32(29,30)25-10-9-14(26)11-18(25)19(27)24-28/h1-8,14,18,26,28H,9-12H2,(H,24,27)/t14-,18+/m0/s1 CXDRRXBTMPCKQG-KBXCAEBGSA-N 50113027 (2R,4S)-4-Hydroxy-1-[4-(2-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL283711 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113027&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10096444 104007378 CHEMBL283711 ZINC13441629 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584814 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2I)cc1 InChI=1S/C19H21IN2O6S/c20-17-4-2-1-3-13(17)12-28-15-6-8-16(9-7-15)29(26,27)22-11-14(23)5-10-18(22)19(24)21-25/h1-4,6-9,14,18,23,25H,5,10-12H2,(H,21,24)/t14-,18-/m1/s1 SRINAMXXQPXTRO-RDTXWAMCSA-N 50113046 (2R,5R)-5-Hydroxy-1-[4-(2-iodo-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL285272 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113046&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278705 104007397 CHEMBL285272 ZINC29205554 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584815 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(Cl)c2)cc1 InChI=1S/C19H21ClN2O6S/c20-14-3-1-2-13(10-14)12-28-16-4-6-17(7-5-16)29(26,27)22-9-8-15(23)11-18(22)19(24)21-25/h1-7,10,15,18,23,25H,8-9,11-12H2,(H,21,24)/t15-,18+/m0/s1 QUHKOMQMEHKSHH-MAUKXSAKSA-N 50113034 (2R,4S)-1-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28942 Disintegrin and metalloproteinase domain-containing protein 17 >30000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113034 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113034&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278412 104007385 CHEMBL28942 ZINC13441615 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584816 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2F)cc1 InChI=1S/C19H21FN2O6S/c20-17-4-2-1-3-13(17)12-28-15-5-7-16(8-6-15)29(26,27)22-10-9-14(23)11-18(22)19(24)21-25/h1-8,14,18,23,25H,9-12H2,(H,21,24)/t14-,18+/m0/s1 MAHFPNFDBUALNZ-KBXCAEBGSA-N 50113032 (2R,4S)-1-[4-(2-Fluoro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28141 Disintegrin and metalloproteinase domain-containing protein 17 >30000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113032 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113032&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278411 104007383 CHEMBL28141 ZINC13441611 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584817 COc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CC[C@H](O)C[C@@H]1C(=O)NO InChI=1S/C20H24N2O7S/c1-28-19-5-3-2-4-14(19)13-29-16-6-8-17(9-7-16)30(26,27)22-11-10-15(23)12-18(22)20(24)21-25/h2-9,15,18,23,25H,10-13H2,1H3,(H,21,24)/t15-,18+/m0/s1 QXWGXKRGYXQPPV-MAUKXSAKSA-N 50113047 (2R,4S)-4-Hydroxy-1-[4-(2-methoxy-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28360 Disintegrin and metalloproteinase domain-containing protein 17 26000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113047 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113047&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9824331 104007398 CHEMBL28360 ZINC13441627 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584818 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc(c2)C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)14-3-1-2-13(10-14)12-31-16-5-7-17(8-6-16)32(29,30)25-11-15(26)4-9-18(25)19(27)24-28/h1-3,5-8,10,15,18,26,28H,4,9,11-12H2,(H,24,27)/t15-,18-/m1/s1 HTWOMTYWAUKKSB-CRAIPNDOSA-N 50113033 (2R,5R)-5-Hydroxy-1-[4-(3-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28351 Disintegrin and metalloproteinase domain-containing protein 17 >30000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113033 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113033&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278522 104007384 CHEMBL28351 ZINC13441640 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584819 Cc1cccc(COc2ccc(cc2)S(=O)(=O)N2CC[C@H](O)C[C@@H]2C(=O)NO)c1 InChI=1S/C20H24N2O6S/c1-14-3-2-4-15(11-14)13-28-17-5-7-18(8-6-17)29(26,27)22-10-9-16(23)12-19(22)20(24)21-25/h2-8,11,16,19,23,25H,9-10,12-13H2,1H3,(H,21,24)/t16-,19+/m0/s1 HRFNCDYTGOTSMJ-QFBILLFUSA-N 50113023 (2R,4S)-4-Hydroxy-1-[4-(3-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28350 Disintegrin and metalloproteinase domain-containing protein 17 >30000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113023&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541748 104007374 CHEMBL28350 ZINC13441621 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50488601 CCOP(=O)(N1Cc2ccccc2C[C@@H]1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H23N2O5P/c1-3-26-27(24,17-10-8-16(25-2)9-11-17)21-13-15-7-5-4-6-14(15)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22)/t18-,27?/m1/s1 RBLCSCFFNCADJO-XZATXCMXSA-N 50171860 ((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL363424 Disintegrin and metalloproteinase domain-containing protein 17 7.2 ChEMBL 10.1016/s0960-894x(03)00292-0 10.7270/Q2KW5FFZ 12781187 Sawa, M; Kurokawa, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171860&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399042 104058052 CHEMBL363424 ZINC13438427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50497515 COc1ccc(cc1)[P@](=O)(OCC(F)F)N1Cc2ccccc2C[C@@H]1C(=O)NO InChI=1S/C19H21F2N2O5P/c1-27-15-6-8-16(9-7-15)29(26,28-12-18(20)21)23-11-14-5-3-2-4-13(14)10-17(23)19(24)22-25/h2-9,17-18,25H,10-12H2,1H3,(H,22,24)/t17-,29+/m1/s1 YYRRVFYCIQQYHU-JWRCQZCYSA-N 50291702 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2-difluoro-ethyl ester::(R)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2-difluoro-ethyl ester::CHEMBL435462 Disintegrin and metalloproteinase domain-containing protein 17 510 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291702&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10477531 104133254 CHEMBL435462 ZINC11687976 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50497516 COc1ccc(cc1)[P@](=O)(OCC(F)(F)F)N1Cc2ccccc2C[C@@H]1C(=O)NO InChI=1S/C19H20F3N2O5P/c1-28-15-6-8-16(9-7-15)30(27,29-12-19(20,21)22)24-11-14-5-3-2-4-13(14)10-17(24)18(25)23-26/h2-9,17,26H,10-12H2,1H3,(H,23,25)/t17-,30+/m1/s1 DZWVTHAIOWIVNT-ZQHDKMAOSA-N 50291704 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2,2-trifluoro-ethyl ester::(R)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2,2,2-trifluoro-ethyl ester::CHEMBL347440 Disintegrin and metalloproteinase domain-containing protein 17 730 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291704&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10478612 104133256 CHEMBL347440 ZINC11686268 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50497535 COc1ccc(cc1)[P@@](=O)(OCCF)N1Cc2ccccc2C[C@@H]1C(=O)NO InChI=1S/C19H22FN2O5P/c1-26-16-6-8-17(9-7-16)28(25,27-11-10-20)22-13-15-5-3-2-4-14(15)12-18(22)19(23)21-24/h2-9,18,24H,10-13H2,1H3,(H,21,23)/t18-,28-/m1/s1 KFUADVZPCULIED-KWMCUTETSA-N 50291707 (S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-fluoro-ethyl ester::CHEMBL347021 Disintegrin and metalloproteinase domain-containing protein 17 180 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291707 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291707&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11811629 104133259 CHEMBL347021 ZINC13438431 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50497538 COc1ccc(cc1)[P@@](=O)(OCCC(F)(F)F)N1Cc2ccccc2C[C@@H]1C(=O)NO InChI=1S/C20H22F3N2O5P/c1-29-16-6-8-17(9-7-16)31(28,30-11-10-20(21,22)23)25-13-15-5-3-2-4-14(15)12-18(25)19(26)24-27/h2-9,18,27H,10-13H2,1H3,(H,24,26)/t18-,31-/m1/s1 SLHHOJZYTMNFRR-WTPASJBYSA-N 50291705 (S)-((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 3,3,3-trifluoro-propyl ester::CHEMBL64689 Disintegrin and metalloproteinase domain-containing protein 17 310 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50291705 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50291705&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11037836 104133257 CHEMBL64689 ZINC13438437 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50497539 CCOP(=O)(N1Cc2ccccc2C[C@@H]1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H23N2O5P/c1-3-26-27(24,17-10-8-16(25-2)9-11-17)21-13-15-7-5-4-6-14(15)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22)/t18-,27?/m1/s1 RBLCSCFFNCADJO-XZATXCMXSA-N 50171860 ((R)-3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL363424 Disintegrin and metalloproteinase domain-containing protein 17 230 ChEMBL 10.1021/jm010349c 10.7270/Q2QV3KS7 11831905 Sawa, M; Tsukamoto, T; Kiyoi, T; Kurokawa, K; Nakajima, F; Nakada, Y; Yokota, K; Inoue, Y; Kondo, H; Yoshino, K Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50171860 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50171860&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44399042 104058052 CHEMBL363424 ZINC13438427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50508412 CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20) PHGLPDURIUEELR-UHFFFAOYSA-N 50161331 2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-acetamide::CHEMBL181244::N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1021/jm900261f 10.7270/Q2JW8DXN 19606871 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Cercignani, G; Marinelli, L; La Pietra, V; Novellino, E; Orlandini, E; Nencetti, S; Tuccinardi, T; Martinelli, A; Lim, NH; Visse, R; Nagase, H; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161331&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10B 4H76,4H3X 10044321 104047647 CHEMBL181244 5140 ZINC03818628 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50508413 CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccc(Cl)cc2)cc1 InChI=1S/C24H25ClN2O6S/c1-17(2)33-27(15-24(28)26-29)34(30,31)23-13-7-20(8-14-23)19-5-11-22(12-6-19)32-16-18-3-9-21(25)10-4-18/h3-14,17,29H,15-16H2,1-2H3,(H,26,28) DKTYDWAJILHINP-UHFFFAOYSA-N 50294124 2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-N-hydroxyacetamide::CHEMBL550350 Disintegrin and metalloproteinase domain-containing protein 17 35000 ChEMBL 10.1021/jm900261f 10.7270/Q2JW8DXN 19606871 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Cercignani, G; Marinelli, L; La Pietra, V; Novellino, E; Orlandini, E; Nencetti, S; Tuccinardi, T; Martinelli, A; Lim, NH; Visse, R; Nagase, H; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294124&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44219901 104135675 CHEMBL550350 ZINC43013084 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50508414 CC(C)ON([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccc(Cl)cc2)cc1 InChI=1S/C27H31ClN2O6S/c1-18(2)26(27(31)29-32)30(36-19(3)4)37(33,34)25-15-9-22(10-16-25)21-7-13-24(14-8-21)35-17-20-5-11-23(28)12-6-20/h5-16,18-19,26,32H,17H2,1-4H3,(H,29,31)/t26-/m1/s1 UTCUOTDVVXFCLJ-AREMUKBSSA-N 50294131 (R)-2-(4'-(4-Chlorobenzyloxy)-N-isopropoxybiphenyl-4-ylsulfonamido)-N-hydroxy-3-methylbutanamide::CHEMBL550548 Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1021/jm900261f 10.7270/Q2JW8DXN 19606871 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Cercignani, G; Marinelli, L; La Pietra, V; Novellino, E; Orlandini, E; Nencetti, S; Tuccinardi, T; Martinelli, A; Lim, NH; Visse, R; Nagase, H; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294131&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44220093 104135682 CHEMBL550548 ZINC43018576 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50508415 CC(C)ON(C(C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(cc1)C(C)C InChI=1S/C23H32N2O5S/c1-15(2)18-7-9-19(10-8-18)20-11-13-21(14-12-20)31(28,29)25(30-17(5)6)22(16(3)4)23(26)24-27/h7-17,22,27H,1-6H3,(H,24,26) UMEYNLZNXJZVAP-UHFFFAOYSA-N 50294132 CHEMBL561963::N-hydroxy-2-(N-isopropoxy-4'-isopropylbiphenyl-4-ylsulfonamido)-3-methylbutanamide Disintegrin and metalloproteinase domain-containing protein 17 14000 ChEMBL 10.1021/jm900261f 10.7270/Q2JW8DXN 19606871 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Cercignani, G; Marinelli, L; La Pietra, V; Novellino, E; Orlandini, E; Nencetti, S; Tuccinardi, T; Martinelli, A; Lim, NH; Visse, R; Nagase, H; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294132&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45268787 104135683 CHEMBL561963 ZINC43075520 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50511276 CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(cc21)N1CCOC1=O)C(O)=O InChI=1S/C20H20N2O7S/c1-11(2)18(19(23)24)21-30(26,27)13-4-5-14-15-9-12(22-7-8-28-20(22)25)3-6-16(15)29-17(14)10-13/h3-6,9-11,18,21H,7-8H2,1-2H3,(H,23,24)/t18-/m0/s1 FWPVXLYOKAOERT-SFHVURJKSA-N 50295479 (S)-3-Methyl-2-(8-(2-oxooxazolidin-3-yl)dibenzo[b,d]furan-3-sulfonamido)butanoic Acid::CHEMBL550038 Disintegrin and metalloproteinase domain-containing protein 17 40000 ChEMBL 10.1021/jm900809r 10.7270/Q21J99SW 19725580 Li, W; Li, J; Wu, Y; Rancati, F; Vallese, S; Raveglia, L; Wu, J; Hotchandani, R; Fuller, N; Cunningham, K; Morgan, P; Fish, S; Krykbaev, R; Xu, X; Tam, S; Goldman, SJ; Abraham, W; Williams, C; Sypek, J; Mansour, TS Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295479&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44224245 104137010 CHEMBL550038 ZINC43014500 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504964 ONC(=O)[C@H]1C[C@]1(Cc1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1)C#N InChI=1S/C28H23N3O3/c29-18-28(16-24(28)27(32)31-33)15-19-10-12-22(13-11-19)34-17-21-14-26(20-6-2-1-3-7-20)30-25-9-5-4-8-23(21)25/h1-14,24,33H,15-17H2,(H,31,32)/t24-,28-/m1/s1 PIRLKANLMCDQSE-UFHPHHKVSA-N 50292680 (1S,2R)-2-cyano-N-hydroxy-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide::CHEMBL497769 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292680&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11575995 104134231 CHEMBL497769 ZINC14001968 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504965 ONC(=O)[C@H]1C[C@]1(Cc1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1)C(=O)NCC1CCNCC1 InChI=1S/C34H36N4O4/c39-32(38-41)29-20-34(29,33(40)36-21-24-14-16-35-17-15-24)19-23-10-12-27(13-11-23)42-22-26-18-31(25-6-2-1-3-7-25)37-30-9-5-4-8-28(26)30/h1-13,18,24,29,35,41H,14-17,19-22H2,(H,36,40)(H,38,39)/t29-,34+/m1/s1 LZHATKQUQHRBAF-SJHOIFEDSA-N 50292685 (1R,2S)-N2-hydroxy-1-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)-N1-(piperidin-4-ylmethyl)cyclopropane-1,2-dicarboxamide::CHEMBL452212 Disintegrin and metalloproteinase domain-containing protein 17 0.630000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292685 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292685&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580806 104134236 CHEMBL452212 ZINC44352095 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504966 CN(C)[C@H]1CCN(C1)C(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C34H36N4O4/c1-37(2)26-16-17-38(21-26)33(40)34(20-29(34)32(39)36-41)19-23-12-14-27(15-13-23)42-22-25-18-31(24-8-4-3-5-9-24)35-30-11-7-6-10-28(25)30/h3-15,18,26,29,41H,16-17,19-22H2,1-2H3,(H,36,39)/t26-,29+,34-/m0/s1 QOTFFMOJDUMNES-SSADEFIASA-N 50292686 (1S,2R)-2-((S)-3-(dimethylamino)pyrrolidine-1-carbonyl)-N-hydroxy-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide::CHEMBL467798 Disintegrin and metalloproteinase domain-containing protein 17 0.540000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292686&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580805 104134237 CHEMBL467798 ZINC44406258 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504967 CN(C)[C@@H]1CCN(C1)C(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C34H36N4O4/c1-37(2)26-16-17-38(21-26)33(40)34(20-29(34)32(39)36-41)19-23-12-14-27(15-13-23)42-22-25-18-31(24-8-4-3-5-9-24)35-30-11-7-6-10-28(25)30/h3-15,18,26,29,41H,16-17,19-22H2,1-2H3,(H,36,39)/t26-,29-,34+/m1/s1 QOTFFMOJDUMNES-DKNOKOKBSA-N 50292687 (1S,2R)-2-((R)-3-(dimethylamino)pyrrolidine-1-carbonyl)-N-hydroxy-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide::CHEMBL443884 Disintegrin and metalloproteinase domain-containing protein 17 0.380000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292687 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292687&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580804 104134238 CHEMBL443884 ZINC44281526 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504968 ONC(=O)[C@H]1C[C@]1(Cc1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1)C(=O)N1CC[C@H](O)C1 InChI=1S/C32H31N3O5/c36-24-14-15-35(19-24)31(38)32(18-27(32)30(37)34-39)17-21-10-12-25(13-11-21)40-20-23-16-29(22-6-2-1-3-7-22)33-28-9-5-4-8-26(23)28/h1-13,16,24,27,36,39H,14-15,17-20H2,(H,34,37)/t24-,27+,32-/m0/s1 VDEIWKFFJJYYCN-YWFNMOQXSA-N 50292688 (1S,2R)-N-hydroxy-2-((S)-3-hydroxypyrrolidine-1-carbonyl)-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide::CHEMBL500112 Disintegrin and metalloproteinase domain-containing protein 17 0.250000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292688 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292688&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580803 104134239 CHEMBL500112 ZINC42803930 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504969 OC[C@@H]1CCCN1C(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C33H33N3O5/c37-20-25-9-6-16-36(25)32(39)33(19-28(33)31(38)35-40)18-22-12-14-26(15-13-22)41-21-24-17-30(23-7-2-1-3-8-23)34-29-11-5-4-10-27(24)29/h1-5,7-8,10-15,17,25,28,37,40H,6,9,16,18-21H2,(H,35,38)/t25-,28+,33-/m0/s1 PHCNKOHEKZYJCZ-OYRZRQNVSA-N 50292681 (1S,2R)-N-hydroxy-2-((S)-2-(hydroxymethyl)pyrrolidine-1-carbonyl)-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide::CHEMBL506057 Disintegrin and metalloproteinase domain-containing protein 17 0.300000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292681 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292681&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580802 104134232 CHEMBL506057 ZINC42835627 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504970 CN(C)C(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)c(F)c2)C[C@@H]1C(=O)NO InChI=1S/C30H28FN3O4/c1-34(2)29(36)30(17-23(30)28(35)33-37)16-19-12-13-27(24(31)14-19)38-18-21-15-26(20-8-4-3-5-9-20)32-25-11-7-6-10-22(21)25/h3-15,23,37H,16-18H2,1-2H3,(H,33,35)/t23-,30+/m1/s1 QCSQWZYXJSYMSJ-DJUQAAIZSA-N 50292682 (1R,2S)-1-(3-fluoro-4-((2-phenylquinolin-4-yl)methoxy)benzyl)-N2-hydroxy-N1,N1-dimethylcyclopropane-1,2-dicarboxamide::CHEMBL496309 Disintegrin and metalloproteinase domain-containing protein 17 0.360000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292682 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292682&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580801 104134233 CHEMBL496309 ZINC40974027 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504971 CN(C)C(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C30H29N3O4/c1-33(2)29(35)30(18-25(30)28(34)32-36)17-20-12-14-23(15-13-20)37-19-22-16-27(21-8-4-3-5-9-21)31-26-11-7-6-10-24(22)26/h3-16,25,36H,17-19H2,1-2H3,(H,32,34)/t25-,30+/m1/s1 JJTUZGDFMUDDFR-RNAHPLFWSA-N 50292689 (1R,2S)-N2-hydroxy-N1,N1-dimethyl-1-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropane-1,2-dicarboxamide::CHEMBL524072 Disintegrin and metalloproteinase domain-containing protein 17 0.280000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292689&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44580800 104134240 CHEMBL524072 ZINC40430484 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504972 NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)N3CCOCC3)c(F)c2)C[C@@H]1C(=O)NO InChI=1S/C26H27FN4O5/c27-20-11-16(13-26(25(28)33)14-19(26)24(32)30-34)5-6-22(20)36-15-17-12-23(31-7-9-35-10-8-31)29-21-4-2-1-3-18(17)21/h1-6,11-12,19,34H,7-10,13-15H2,(H2,28,33)(H,30,32)/t19-,26+/m1/s1 MCEIXJWWBPSHMV-BCHFMIIMSA-N 50292690 (1R,2S)-1-(3-fluoro-4-((2-morpholinoquinolin-4-yl)methoxy)benzyl)-N2-hydroxycyclopropane-1,2-dicarboxamide::CHEMBL467747 Disintegrin and metalloproteinase domain-containing protein 17 0.210000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292690 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292690&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581166 104134241 CHEMBL467747 ZINC40874735 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504973 NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)N3CCCC3)c(F)c2)C[C@@H]1C(=O)NO InChI=1S/C26H27FN4O4/c27-20-11-16(13-26(25(28)33)14-19(26)24(32)30-34)7-8-22(20)35-15-17-12-23(31-9-3-4-10-31)29-21-6-2-1-5-18(17)21/h1-2,5-8,11-12,19,34H,3-4,9-10,13-15H2,(H2,28,33)(H,30,32)/t19-,26+/m1/s1 DTDKZQRVEWCQKP-BCHFMIIMSA-N 50292691 (1R,2S)-1-(3-fluoro-4-((2-(pyrrolidin-1-yl)quinolin-4-yl)methoxy)benzyl)-N2-hydroxycyclopropane-1,2-dicarboxamide::CHEMBL468778 Disintegrin and metalloproteinase domain-containing protein 17 0.150000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292691&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581165 104134242 CHEMBL468778 ZINC40893892 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504974 CNc1cc(COc2ccc(C[C@@]3(C[C@@H]3C(=O)NO)C(N)=O)cc2F)c2ccccc2n1 InChI=1S/C23H23FN4O4/c1-26-20-9-14(15-4-2-3-5-18(15)27-20)12-32-19-7-6-13(8-17(19)24)10-23(22(25)30)11-16(23)21(29)28-31/h2-9,16,31H,10-12H2,1H3,(H2,25,30)(H,26,27)(H,28,29)/t16-,23+/m1/s1 QMSQXOQMJJNFQO-MWTRTKDXSA-N 50292692 (1R,2S)-1-(3-fluoro-4-((2-(methylamino)quinolin-4-yl)methoxy)benzyl)-N2-hydroxycyclopropane-1,2-dicarboxamide::CHEMBL468777 Disintegrin and metalloproteinase domain-containing protein 17 0.760000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292692 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292692&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581164 104134243 CHEMBL468777 ZINC40893889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504975 Cn1ccc(n1)-c1cc(COc2ccc(C[C@@]3(C[C@@H]3C(=O)NO)C(N)=O)cc2F)c2ccccc2n1 InChI=1S/C26H24FN5O4/c1-32-9-8-21(30-32)22-11-16(17-4-2-3-5-20(17)29-22)14-36-23-7-6-15(10-19(23)27)12-26(25(28)34)13-18(26)24(33)31-35/h2-11,18,35H,12-14H2,1H3,(H2,28,34)(H,31,33)/t18-,26+/m1/s1 RWXQTLWYBFBYNB-DWXRJYCRSA-N 50292693 (1R,2S)-1-(3-fluoro-4-((2-(1-methyl-1H-pyrazol-3-yl)quinolin-4-yl)methoxy)benzyl)-N2-hydroxycyclopropane-1,2-dicarboxamide::CHEMBL512117 Disintegrin and metalloproteinase domain-containing protein 17 0.150000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292693 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292693&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581163 104134244 CHEMBL512117 ZINC40394727 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504976 NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3cccnc3)c(F)c2)C[C@@H]1C(=O)NO InChI=1S/C27H23FN4O4/c28-21-10-16(12-27(26(29)34)13-20(27)25(33)32-35)7-8-24(21)36-15-18-11-23(17-4-3-9-30-14-17)31-22-6-2-1-5-19(18)22/h1-11,14,20,35H,12-13,15H2,(H2,29,34)(H,32,33)/t20-,27+/m1/s1 YGDNTXRQOGWMGK-HRFSGMKKSA-N 50292694 (1R,2S)-1-(3-fluoro-4-((2-(pyridin-3-yl)quinolin-4-yl)methoxy)benzyl)-N2-hydroxycyclopropane-1,2-dicarboxamide::CHEMBL495569 Disintegrin and metalloproteinase domain-containing protein 17 0.140000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292694 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292694&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581139 104134245 CHEMBL495569 ZINC40429807 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504977 NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)c(F)c2)C[C@@H]1C(=O)NO InChI=1S/C28H24FN3O4/c29-22-12-17(14-28(27(30)34)15-21(28)26(33)32-35)10-11-25(22)36-16-19-13-24(18-6-2-1-3-7-18)31-23-9-5-4-8-20(19)23/h1-13,21,35H,14-16H2,(H2,30,34)(H,32,33)/t21-,28+/m1/s1 ZVRPHGZPZLMEPV-PIKZIKFNSA-N 26524 (1R,2S)-1-({3-fluoro-4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)-2-N-hydroxycyclopropane-1,2-dicarboxamide::hydroxamate-cyclopropyl compound, 1 Disintegrin and metalloproteinase domain-containing protein 17 0.140000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26524 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26524&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25138228 56464961 ZINC40862219 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504978 NC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C28H25N3O4/c29-27(33)28(16-23(28)26(32)31-34)15-18-10-12-21(13-11-18)35-17-20-14-25(19-6-2-1-3-7-19)30-24-9-5-4-8-22(20)24/h1-14,23,34H,15-17H2,(H2,29,33)(H,31,32)/t23-,28+/m1/s1 BKHGWMSYWJIRLD-LXFBAYGMSA-N 26525 (1S,2R)-1-N-hydroxy-2-({4-[(2-phenylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::hydroxamate-cyclopropyl compound, 2 Disintegrin and metalloproteinase domain-containing protein 17 0.180000 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26525 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26525&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 615 3E8R 24978491 56464962 ZINC40393256 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504979 CCc1cc(COc2ccc(C[C@@]3(C[C@@H]3C(=O)NO)C(N)=O)cc2)c2ccccc2n1 InChI=1S/C24H25N3O4/c1-2-17-11-16(19-5-3-4-6-21(19)26-17)14-31-18-9-7-15(8-10-18)12-24(23(25)29)13-20(24)22(28)27-30/h3-11,20,30H,2,12-14H2,1H3,(H2,25,29)(H,27,28)/t20-,24+/m1/s1 CUWRDADPFHLEIY-YKSBVNFPSA-N 50292695 (1R,2S)-1-(4-((2-ethylquinolin-4-yl)methoxy)benzyl)-N2-hydroxycyclopropane-1,2-dicarboxamide::CHEMBL496983 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292695&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581138 104134246 CHEMBL496983 ZINC40975648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504980 Cc1cc(COc2ccc(C[C@@]3(C[C@@H]3C(=O)NO)C(N)=O)cc2)c2ccccc2n1 InChI=1S/C23H23N3O4/c1-14-10-16(18-4-2-3-5-20(18)25-14)13-30-17-8-6-15(7-9-17)11-23(22(24)28)12-19(23)21(27)26-29/h2-10,19,29H,11-13H2,1H3,(H2,24,28)(H,26,27)/t19-,23+/m1/s1 ZWPPXQSIUHCIOD-XXBNENTESA-N 23487 (1S,2R)-1-N-hydroxy-2-({4-[(2-methylquinolin-4-yl)methoxy]phenyl}methyl)cyclopropane-1,2-dicarboxamide::BMCL1954 Compound 3::hydroxamate deriv., 78 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23487 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23487&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24799779 50091749 ZINC29135236 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504981 CCOC(=O)[C@@]1(Cc2ccc(OCc3ccnc(c3)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C26H26N2O5/c1-2-32-25(30)26(16-22(26)24(29)28-31)15-18-8-10-21(11-9-18)33-17-19-12-13-27-23(14-19)20-6-4-3-5-7-20/h3-14,22,31H,2,15-17H2,1H3,(H,28,29)/t22-,26+/m1/s1 JHBDZTRMXYRABN-GJZUVCINSA-N 50292696 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenylpyridin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL496368 Disintegrin and metalloproteinase domain-containing protein 17 37 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292696&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581113 104134247 CHEMBL496368 ZINC40428731 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504982 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3cccnc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C29H27N3O5/c1-2-36-28(34)29(16-24(29)27(33)32-35)15-19-9-11-22(12-10-19)37-18-21-14-26(20-6-5-13-30-17-20)31-25-8-4-3-7-23(21)25/h3-14,17,24,35H,2,15-16,18H2,1H3,(H,32,33)/t24-,29+/m1/s1 BDVFOWBSUKDWDA-GIGWZHCTSA-N 50292697 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-(pyridin-3-yl)quinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL496367 Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292697 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292697&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581112 104134248 CHEMBL496367 ZINC40974529 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504983 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)-c3ccccc3)cc2)C[C@@H]1C(=O)NO InChI=1S/C30H28N2O5/c1-2-36-29(34)30(18-25(30)28(33)32-35)17-20-12-14-23(15-13-20)37-19-22-16-27(21-8-4-3-5-9-21)31-26-11-7-6-10-24(22)26/h3-16,25,35H,2,17-19H2,1H3,(H,32,33)/t25-,30+/m1/s1 OKNJOSGDEWUQIH-RNAHPLFWSA-N 50292683 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL495555 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292683 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292683&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581111 104134234 CHEMBL495555 ZINC40953995 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504984 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(CC(C)C)nc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C28H32N2O5/c1-4-34-27(32)28(16-24(28)26(31)30-33)15-19-9-11-22(12-10-19)35-17-20-14-21(13-18(2)3)29-25-8-6-5-7-23(20)25/h5-12,14,18,24,33H,4,13,15-17H2,1-3H3,(H,30,31)/t24-,28+/m1/s1 QNHYWOQVUXWWKX-YWEHKCAJSA-N 50292698 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-isobutylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL495747 Disintegrin and metalloproteinase domain-containing protein 17 18 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292698 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292698&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581094 104134249 CHEMBL495747 ZINC40431100 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504985 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(CC)nc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C26H28N2O5/c1-3-19-13-18(21-7-5-6-8-23(21)27-19)16-33-20-11-9-17(10-12-20)14-26(25(30)32-4-2)15-22(26)24(29)28-31/h5-13,22,31H,3-4,14-16H2,1-2H3,(H,28,29)/t22-,26+/m1/s1 QAKROBSXHIRVDA-GJZUVCINSA-N 50292699 (1R,2S)-ethyl 1-(4-((2-ethylquinolin-4-yl)methoxy)benzyl)-2-(hydroxycarbamoyl)cyclopropanecarboxylate::CHEMBL495538 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292699 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292699&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581093 104134250 CHEMBL495538 ZINC40430842 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504986 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(nc4ccccc34)C(F)(F)F)cc2)C[C@@H]1C(=O)NO InChI=1S/C25H23F3N2O5/c1-2-34-23(32)24(13-19(24)22(31)30-33)12-15-7-9-17(10-8-15)35-14-16-11-21(25(26,27)28)29-20-6-4-3-5-18(16)20/h3-11,19,33H,2,12-14H2,1H3,(H,30,31)/t19-,24+/m1/s1 GBUGLSYBWAMTLA-DVECYGJZSA-N 50292700 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-(trifluoromethyl)quinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL523892 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292700 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292700&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581092 104134251 CHEMBL523892 ZINC40972657 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504987 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)c(Br)c2)C[C@@H]1C(=O)NO InChI=1S/C25H25BrN2O5/c1-3-32-24(30)25(13-19(25)23(29)28-31)12-16-8-9-22(20(26)11-16)33-14-17-10-15(2)27-21-7-5-4-6-18(17)21/h4-11,19,31H,3,12-14H2,1-2H3,(H,28,29)/t19-,25+/m1/s1 LQKKQRMPHRHYOQ-CLOONOSVSA-N 50292701 (1R,2S)-ethyl 1-(3-bromo-4-((2-methylquinolin-4-yl)methoxy)benzyl)-2-(hydroxycarbamoyl)cyclopropanecarboxylate::CHEMBL495537 Disintegrin and metalloproteinase domain-containing protein 17 381 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292701 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292701&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581091 104134252 CHEMBL495537 ZINC40972393 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504988 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)c(Cl)c2)C[C@@H]1C(=O)NO InChI=1S/C25H25ClN2O5/c1-3-32-24(30)25(13-19(25)23(29)28-31)12-16-8-9-22(20(26)11-16)33-14-17-10-15(2)27-21-7-5-4-6-18(17)21/h4-11,19,31H,3,12-14H2,1-2H3,(H,28,29)/t19-,25+/m1/s1 QDNVXUBEGWVOKL-CLOONOSVSA-N 50292702 (1R,2S)-ethyl 1-(3-chloro-4-((2-methylquinolin-4-yl)methoxy)benzyl)-2-(hydroxycarbamoyl)cyclopropanecarboxylate::CHEMBL496357 Disintegrin and metalloproteinase domain-containing protein 17 158 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292702 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292702&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581073 104134253 CHEMBL496357 ZINC40973767 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504989 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)c(F)c2)C[C@@H]1C(=O)NO InChI=1S/C25H25FN2O5/c1-3-32-24(30)25(13-19(25)23(29)28-31)12-16-8-9-22(20(26)11-16)33-14-17-10-15(2)27-21-7-5-4-6-18(17)21/h4-11,19,31H,3,12-14H2,1-2H3,(H,28,29)/t19-,25+/m1/s1 QORKFWILWPYIJT-CLOONOSVSA-N 50292703 (1R,2S)-ethyl 1-(3-fluoro-4-((2-methylquinolin-4-yl)methoxy)benzyl)-2-(hydroxycarbamoyl)cyclopropanecarboxylate::CHEMBL523930 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292703 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292703&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581072 104134254 CHEMBL523930 ZINC40429306 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50504990 CCOC(=O)[C@@]1(Cc2ccc(OCc3cc(C)nc4ccccc34)cc2)C[C@@H]1C(=O)NO InChI=1S/C25H26N2O5/c1-3-31-24(29)25(14-21(25)23(28)27-30)13-17-8-10-19(11-9-17)32-15-18-12-16(2)26-22-7-5-4-6-20(18)22/h4-12,21,30H,3,13-15H2,1-2H3,(H,27,28)/t21-,25+/m1/s1 YOOJSKRBENNWQY-BWKNWUBXSA-N 50292684 (1R,2S)-ethyl 2-(hydroxycarbamoyl)-1-(4-((2-methylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxylate::CHEMBL497810 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2008.09.045 10.7270/Q2N29WZX 18835710 Mazzola, RD; Zhu, Z; Sinning, L; McKittrick, B; Lavey, B; Spitler, J; Kozlowski, J; Neng-Yang, S; Zhou, G; Guo, Z; Orth, P; Madison, V; Sun, J; Lundell, D; Niu, X Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50292684 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50292684&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44581071 104134235 CHEMBL497810 ZINC40972801 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50548033 Cc1cc(cc(n1)C(=O)NCc1ccc(F)cc1)-c1nnn(C[C@H]2CC[C@@H](CC2)C(O)=O)n1 InChI=1S/C23H25FN6O3/c1-14-10-18(11-20(26-14)22(31)25-12-15-4-8-19(24)9-5-15)21-27-29-30(28-21)13-16-2-6-17(7-3-16)23(32)33/h4-5,8-11,16-17H,2-3,6-7,12-13H2,1H3,(H,25,31)(H,32,33)/t16-,17- KOTGODCEORJYIF-QAQDUYKDSA-N 50305842 CHEMBL603656::trans-4-((5-(2-(4-fluorobenzylcarbamoyl)-6-methylpyridin-4-yl)-2H-tetrazol-2-yl)methyl)cyclohexanecarboxylic acid Disintegrin and metalloproteinase domain-containing protein 17 >25000 ChEMBL 10.1016/j.bmcl.2009.11.081 10.7270/Q2JS9QHB 20005097 Schnute, ME; O'Brien, PM; Nahra, J; Morris, M; Howard Roark, W; Hanau, CE; Ruminski, PG; Scholten, JA; Fletcher, TR; Hamper, BC; Carroll, JN; Patt, WC; Shieh, HS; Collins, B; Pavlovsky, AG; Palmquist, KE; Aston, KW; Hitchcock, J; Rogers, MD; McDonald, J; Johnson, AR; Munie, GE; Wittwer, AJ; Man, CF; Settle, SL; Nemirovskiy, O; Vickery, LE; Agawal, A; Dyer, RD; Sunyer, T Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305842&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 25183768 104160203 CHEMBL603656 ZINC43203228 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50535460 OC(CCc1ccc(cc1)-c1ccccc1)CC(O)=O InChI=1S/C17H18O3/c18-16(12-17(19)20)11-8-13-6-9-15(10-7-13)14-4-2-1-3-5-14/h1-7,9-10,16,18H,8,11-12H2,(H,19,20) ILGSIIFHQGOKKV-UHFFFAOYSA-N 50300465 (+/-)5-(biphenyl-4-yl)-3-hydroxypentanoic acid::5-(biphenyl-4-yl)-3-hydroxypentanoic acid::CHEMBL572982 Disintegrin and metalloproteinase domain-containing protein 17 >98000 ChEMBL 10.1016/j.bmcl.2009.07.155 10.7270/Q2RR1Z91 19703773 Holmes, IP; Gaines, S; Watson, SP; Lorthioir, O; Walker, A; Baddeley, SJ; Herbert, S; Egan, D; Convery, MA; Singh, OM; Gross, JW; Strelow, JM; Smith, RH; Amour, AJ; Brown, D; Martin, SL GSK Medicines Research Centre http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 077 2WO8 11391583 104154826 CHEMBL572982 C03834 ZINC45285504 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566824 ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NS(=O)(=O)c1ccc(cc1)-c1ccccc1C(F)(F)F InChI=1S/C25H20F3N3O6S/c26-25(27,28)20-8-4-3-5-17(20)15-9-11-16(12-10-15)38(36,37)30-21(22(32)29-35)13-14-31-23(33)18-6-1-2-7-19(18)24(31)34/h1-12,21,30,35H,13-14H2,(H,29,32)/t21-/m1/s1 HOKBADYASDUFAM-OAQYLSRUSA-N 50314219 (R)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxy-2-(2'-(trifluoromethyl)biphenyl-4-ylsulfonamido)butanamide::CHEMBL1093689 Disintegrin and metalloproteinase domain-containing protein 17 44000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314219&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45380191 104148580 CHEMBL1093689 ZINC49784763 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566829 CC(=O)NCC[C@@H](NS(=O)(=O)c1ccc(Br)cc1)C(=O)NO InChI=1S/C12H16BrN3O5S/c1-8(17)14-7-6-11(12(18)15-19)16-22(20,21)10-4-2-9(13)3-5-10/h2-5,11,16,19H,6-7H2,1H3,(H,14,17)(H,15,18)/t11-/m1/s1 XXZNXULRAJJTRV-LLVKDONJSA-N 50314220 (R)-4-acetamido-2-(4-bromophenylsulfonamido)-N-hydroxybutanamide::CHEMBL1093690 Disintegrin and metalloproteinase domain-containing protein 17 110 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314220&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378250 104148581 CHEMBL1093690 ZINC49111770 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566834 ONC(=O)[C@@H](CCN1C(=O)c2ccccc2C1=O)NS(=O)(=O)c1ccc(Br)cc1 InChI=1S/C18H16BrN3O6S/c19-11-5-7-12(8-6-11)29(27,28)21-15(16(23)20-26)9-10-22-17(24)13-3-1-2-4-14(13)18(22)25/h1-8,15,21,26H,9-10H2,(H,20,23)/t15-/m1/s1 MTDVSXPXWCWOED-OAHLLOKOSA-N 50314221 (R)-2-(4-bromophenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1092104 Disintegrin and metalloproteinase domain-containing protein 17 210 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314221&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378251 104148582 CHEMBL1092104 ZINC49072373 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566849 CC#CCOc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C26H29N3O7S/c1-4-5-16-36-19-10-12-20(13-11-19)37(34,35)29(17-18(2)3)23(24(30)27-33)14-15-28-25(31)21-8-6-7-9-22(21)26(28)32/h6-13,18,23,33H,14-17H2,1-3H3,(H,27,30)/t23-/m1/s1 WMJKIJLFVOMJDF-HSZRJFAPSA-N 50314224 (R)-2-(4-(but-2-ynyloxy)-N-isobutylphenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1088878 Disintegrin and metalloproteinase domain-containing protein 17 59 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314224&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378254 104148585 CHEMBL1088878 ZINC49126000 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566860 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566869 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566881 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCN1C(=O)c2ccccc2C1=O)C(=O)NO InChI=1S/C22H21N3O7S/c1-2-3-14-32-15-8-10-16(11-9-15)33(30,31)24-19(20(26)23-29)12-13-25-21(27)17-6-4-5-7-18(17)22(25)28/h4-11,19,24,29H,12-14H2,1H3,(H,23,26)/t19-/m1/s1 MWMRJYLEVAWDDL-LJQANCHMSA-N 50314223 (R)-2-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(1,3-dioxoisoindolin-2-yl)-N-hydroxybutanamide::CHEMBL1089843 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378253 104148584 CHEMBL1089843 ZINC49068565 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555481 COc1cccc(c1)N1CCN(CC1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C21H27N3O5S/c1-29-16-5-2-4-15(14-16)23-9-11-24(12-10-23)21(28)19(26)18(25)20(27)22-8-7-17-6-3-13-30-17/h2-6,13-14,18-19,25-26H,7-12H2,1H3,(H,22,27)/t18-,19-/m1/s1 CXOLUGYAQQDOJN-RTBURBONSA-N 50309131 (2R,3R)-2,3-dihydroxy-4-(4-(3-methoxyphenyl)piperazin-1-yl)-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL599173 Disintegrin and metalloproteinase domain-containing protein 17 400 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309131&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11568227 104163492 CHEMBL599173 ZINC35827453 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555482 O[C@H]([C@@H](O)C(=O)N1CCN(CC1)c1ccccc1Cl)C(=O)NCCc1cccs1 InChI=1S/C20H24ClN3O4S/c21-15-5-1-2-6-16(15)23-9-11-24(12-10-23)20(28)18(26)17(25)19(27)22-8-7-14-4-3-13-29-14/h1-6,13,17-18,25-26H,7-12H2,(H,22,27)/t17-,18-/m1/s1 AZEKZZSSVLIPCQ-QZTJIDSGSA-N 50309132 (2R,3R)-4-(4-(2-chlorophenyl)piperazin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::(2R,3R)-4-[4-(2-chlorophenyl)piperazin-1-yl]-2,3-dihydroxy-4-oxo-N-(2-thiophen-2-ylethyl)butanamide::CHEMBL605764 Disintegrin and metalloproteinase domain-containing protein 17 400 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309132&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 403 3KMC 11640694 104163493 CHEMBL605764 ZINC35984497 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555483 O[C@H]([C@@H](O)C(=O)N1CCC(Cc2ccccc2)CC1)C(=O)NCCc1cccs1 InChI=1S/C22H28N2O4S/c25-19(21(27)23-11-8-18-7-4-14-29-18)20(26)22(28)24-12-9-17(10-13-24)15-16-5-2-1-3-6-16/h1-7,14,17,19-20,25-26H,8-13,15H2,(H,23,27)/t19-,20-/m1/s1 DRQJFQZGGDLNBQ-WOJBJXKFSA-N 50309133 (2R,3R)-4-(4-benzylpiperidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL598358 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309133&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230272 104163494 CHEMBL598358 ZINC45355334 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555484 CN(C1CCCCC1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C17H26N2O4S/c1-19(12-6-3-2-4-7-12)17(23)15(21)14(20)16(22)18-10-9-13-8-5-11-24-13/h5,8,11-12,14-15,20-21H,2-4,6-7,9-10H2,1H3,(H,18,22)/t14-,15-/m1/s1 SKGDBEJWKRHJAE-HUUCEWRRSA-N 50309134 (2R,3R)-N1-cyclohexyl-2,3-dihydroxy-N1-methyl-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL597945 Disintegrin and metalloproteinase domain-containing protein 17 1400 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309134&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230317 104163495 CHEMBL597945 ZINC45355256 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555485 O[C@H]([C@@H](O)C(=O)N1CCN(CC1)c1ccccn1)C(=O)NCCc1cccs1 InChI=1S/C19H24N4O4S/c24-16(18(26)21-8-6-14-4-3-13-28-14)17(25)19(27)23-11-9-22(10-12-23)15-5-1-2-7-20-15/h1-5,7,13,16-17,24-25H,6,8-12H2,(H,21,26)/t16-,17-/m1/s1 GQQFYTQVBCYHQX-IAGOWNOFSA-N 50309135 (2R,3R)-2,3-dihydroxy-4-oxo-4-(4-(pyridin-2-yl)piperazin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL597139 Disintegrin and metalloproteinase domain-containing protein 17 2500 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309135 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309135&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230320 104163496 CHEMBL597139 ZINC45366001 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555486 CN(C)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C12H18N2O4S/c1-14(2)12(18)10(16)9(15)11(17)13-6-5-8-4-3-7-19-8/h3-4,7,9-10,15-16H,5-6H2,1-2H3,(H,13,17)/t9-,10-/m1/s1 KTPYHCDQOGGTRF-NXEZZACHSA-N 50309136 (2R,3R)-2,3-dihydroxy-N1,N1-dimethyl-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL597340 Disintegrin and metalloproteinase domain-containing protein 17 1300 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309136&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230321 104163497 CHEMBL597340 ZINC45365531 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555487 CN(Cc1ccccc1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C18H22N2O4S/c1-20(12-13-6-3-2-4-7-13)18(24)16(22)15(21)17(23)19-10-9-14-8-5-11-25-14/h2-8,11,15-16,21-22H,9-10,12H2,1H3,(H,19,23)/t15-,16-/m1/s1 SGWJFPIILMLPGR-HZPDHXFCSA-N 50309137 (2R,3R)-N1-benzyl-2,3-dihydroxy-N1-methyl-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL592294 Disintegrin and metalloproteinase domain-containing protein 17 764 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309137&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11717506 104163498 CHEMBL592294 ZINC34640964 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555488 CN(CCc1ccccc1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C19H24N2O4S/c1-21(12-10-14-6-3-2-4-7-14)19(25)17(23)16(22)18(24)20-11-9-15-8-5-13-26-15/h2-8,13,16-17,22-23H,9-12H2,1H3,(H,20,24)/t16-,17-/m1/s1 CIDXMLVRAFPLQG-IAGOWNOFSA-N 50309138 (2R,3R)-2,3-dihydroxy-N1-methyl-N1-phenethyl-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL592295 Disintegrin and metalloproteinase domain-containing protein 17 1280 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309138&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230364 104163499 CHEMBL592295 ZINC45339494 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555489 CN(Cc1ccco1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C16H20N2O5S/c1-18(10-11-4-2-8-23-11)16(22)14(20)13(19)15(21)17-7-6-12-5-3-9-24-12/h2-5,8-9,13-14,19-20H,6-7,10H2,1H3,(H,17,21)/t13-,14-/m1/s1 QUXVCXBSAQVHTE-ZIAGYGMSSA-N 50309139 (2R,3R)-N1-(furan-2-ylmethyl)-2,3-dihydroxy-N1-methyl-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL604458 Disintegrin and metalloproteinase domain-containing protein 17 1020 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309139&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230365 104163500 CHEMBL604458 ZINC45386474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555490 CN(Cc1cccnc1)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C17H21N3O4S/c1-20(11-12-4-2-7-18-10-12)17(24)15(22)14(21)16(23)19-8-6-13-5-3-9-25-13/h2-5,7,9-10,14-15,21-22H,6,8,11H2,1H3,(H,19,23)/t14-,15-/m1/s1 MCDYFPXMMMPQQB-HUUCEWRRSA-N 50309140 (2R,3R)-2,3-dihydroxy-N1-methyl-N1-(pyridin-3-ylmethyl)-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL600680 Disintegrin and metalloproteinase domain-containing protein 17 943 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309140&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11667693 104163501 CHEMBL600680 ZINC38214860 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555491 C[C@H](N(C)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1)c1ccccc1 InChI=1S/C19H24N2O4S/c1-13(14-7-4-3-5-8-14)21(2)19(25)17(23)16(22)18(24)20-11-10-15-9-6-12-26-15/h3-9,12-13,16-17,22-23H,10-11H2,1-2H3,(H,20,24)/t13-,16+,17+/m0/s1 CJFNWYWHGOFDCX-IAOVAPTHSA-N 50309141 (2R,3R)-2,3-dihydroxy-N1-methyl-N1-((S)-1-phenylethyl)-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL591529 Disintegrin and metalloproteinase domain-containing protein 17 487 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309141&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11682301 104163502 CHEMBL591529 ZINC38238622 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555492 C[C@@H](N(C)C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1)c1ccccc1 InChI=1S/C19H24N2O4S/c1-13(14-7-4-3-5-8-14)21(2)19(25)17(23)16(22)18(24)20-11-10-15-9-6-12-26-15/h3-9,12-13,16-17,22-23H,10-11H2,1-2H3,(H,20,24)/t13-,16-,17-/m1/s1 CJFNWYWHGOFDCX-KBRIMQKVSA-N 50309142 (2R,3R)-2,3-dihydroxy-N1-methyl-N1-((R)-1-phenylethyl)-N4-(2-(thiophen-2-yl)ethyl)succinamide::CHEMBL592721 Disintegrin and metalloproteinase domain-containing protein 17 238 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309142&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11509086 104163503 CHEMBL592721 ZINC34600742 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555493 O[C@H]([C@@H](O)C(=O)N1CCCCC1c1ccccc1)C(=O)NCCc1cccs1 InChI=1S/C21H26N2O4S/c24-18(20(26)22-12-11-16-9-6-14-28-16)19(25)21(27)23-13-5-4-10-17(23)15-7-2-1-3-8-15/h1-3,6-9,14,17-19,24-25H,4-5,10-13H2,(H,22,26)/t17?,18-,19-/m1/s1 CJECZLMWLDBDOZ-OMKBGSMGSA-N 50309143 (2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpiperidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL592722 Disintegrin and metalloproteinase domain-containing protein 17 325 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309143&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230411 104163504 CHEMBL592722 ZINC45340102 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555494 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccn1)C(=O)NCCc1cccs1 InChI=1S/C19H23N3O4S/c23-16(18(25)21-10-8-13-5-4-12-27-13)17(24)19(26)22-11-3-7-15(22)14-6-1-2-9-20-14/h1-2,4-6,9,12,15-17,23-24H,3,7-8,10-11H2,(H,21,25)/t15?,16-,17-/m1/s1 FHGPIBDBYLIJQI-YJEKIOLLSA-N 50309144 (2R,3R)-2,3-dihydroxy-4-oxo-4-(2-(pyridin-2-yl)pyrrolidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL604935 Disintegrin and metalloproteinase domain-containing protein 17 188 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309144&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11531219 104163505 CHEMBL604935 ZINC45375337 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555495 O[C@H]([C@@H](O)C(=O)N1CCCC1c1nccs1)C(=O)NCCc1cccs1 InChI=1S/C17H21N3O4S2/c21-13(15(23)18-6-5-11-3-2-9-25-11)14(22)17(24)20-8-1-4-12(20)16-19-7-10-26-16/h2-3,7,9-10,12-14,21-22H,1,4-6,8H2,(H,18,23)/t12?,13-,14-/m1/s1 FDHFCQQIUWNICS-ILMHWDKJSA-N 50309145 (2R,3R)-2,3-dihydroxy-4-oxo-4-(2-(thiazol-2-yl)pyrrolidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL599156 Disintegrin and metalloproteinase domain-containing protein 17 164 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309145&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230472 104163506 CHEMBL599156 ZINC45366391 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555496 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1Cl)C(=O)NCCc1cccs1 InChI=1S/C20H23ClN2O4S/c21-15-7-2-1-6-14(15)16-8-3-11-23(16)20(27)18(25)17(24)19(26)22-10-9-13-5-4-12-28-13/h1-2,4-7,12,16-18,24-25H,3,8-11H2,(H,22,26)/t16?,17-,18-/m1/s1 PPCRCDGKHOSSFZ-UKKPGEIXSA-N 50309146 (2R,3R)-4-(2-(2-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL590342 Disintegrin and metalloproteinase domain-containing protein 17 323 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309146&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11560876 104163507 CHEMBL590342 ZINC35818307 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555497 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCCc1cccs1 InChI=1S/C20H23ClN2O4S/c21-14-5-1-4-13(12-14)16-7-2-10-23(16)20(27)18(25)17(24)19(26)22-9-8-15-6-3-11-28-15/h1,3-6,11-12,16-18,24-25H,2,7-10H2,(H,22,26)/t16?,17-,18-/m1/s1 LIKQSFURRNSUMR-UKKPGEIXSA-N 50309147 (2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL590343 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309147&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11697504 104163508 CHEMBL590343 ZINC38268845 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555498 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccc(Cl)cc1)C(=O)NCCc1cccs1 InChI=1S/C20H23ClN2O4S/c21-14-7-5-13(6-8-14)16-4-1-11-23(16)20(27)18(25)17(24)19(26)22-10-9-15-3-2-12-28-15/h2-3,5-8,12,16-18,24-25H,1,4,9-11H2,(H,22,26)/t16?,17-,18-/m1/s1 VNSPSLSHFDZIPO-UKKPGEIXSA-N 50309148 (2R,3R)-4-(2-(4-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL600168 Disintegrin and metalloproteinase domain-containing protein 17 755 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309148 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309148&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11683254 104163509 CHEMBL600168 ZINC38239599 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555499 CN(CCc1cccs1)C(=O)[C@H](O)[C@@H](O)C(=O)N1CCCC1c1cccc(C)c1 InChI=1S/C22H28N2O4S/c1-15-6-3-7-16(14-15)18-9-4-11-24(18)22(28)20(26)19(25)21(27)23(2)12-10-17-8-5-13-29-17/h3,5-8,13-14,18-20,25-26H,4,9-12H2,1-2H3/t18?,19-,20-/m1/s1 MNYVUMZYVJSDSO-FXJNCMGBSA-N 50309149 (2R,3R)-2,3-dihydroxy-N-methyl-4-oxo-N-(2-(thiophen-2-yl)ethyl)-4-(2-m-tolylpyrrolidin-1-yl)butanamide::CHEMBL590821 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309149 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309149&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229743 104163510 CHEMBL590821 ZINC45338498 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555500 COc1cccc(c1)C1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N(C)CCc1cccs1 InChI=1S/C22H28N2O5S/c1-23(12-10-17-8-5-13-30-17)21(27)19(25)20(26)22(28)24-11-4-9-18(24)15-6-3-7-16(14-15)29-2/h3,5-8,13-14,18-20,25-26H,4,9-12H2,1-2H3/t18?,19-,20-/m1/s1 NXUUUZSLVWPRDS-FXJNCMGBSA-N 50309150 (2R,3R)-2,3-dihydroxy-4-(2-(3-methoxyphenyl)pyrrolidin-1-yl)-N-methyl-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL590822 Disintegrin and metalloproteinase domain-containing protein 17 33 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309150 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309150&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229744 104163511 CHEMBL590822 ZINC45338502 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555501 CN(C)c1cccc(c1)C1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C22H29N3O4S/c1-24(2)16-7-3-6-15(14-16)18-9-4-12-25(18)22(29)20(27)19(26)21(28)23-11-10-17-8-5-13-30-17/h3,5-8,13-14,18-20,26-27H,4,9-12H2,1-2H3,(H,23,28)/t18?,19-,20-/m1/s1 LYVWDELEASGECE-FXJNCMGBSA-N 50309151 (2R,3R)-4-(2-(3-(dimethylamino)phenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL591535 Disintegrin and metalloproteinase domain-containing protein 17 41 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309151 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309151&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11524821 104163512 CHEMBL591535 ZINC45335815 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555502 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccccc1 InChI=1S/C21H23ClN2O4/c22-16-9-4-8-15(12-16)17-10-5-11-24(17)21(28)19(26)18(25)20(27)23-13-14-6-2-1-3-7-14/h1-4,6-9,12,17-19,25-26H,5,10-11,13H2,(H,23,27)/t17?,18-,19-/m1/s1 UPSOWFNLCOSXGA-OMKBGSMGSA-N 50309152 (2R,3R)-N-benzyl-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL606458 Disintegrin and metalloproteinase domain-containing protein 17 1440 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309152 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309152&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11668526 104163513 CHEMBL606458 ZINC38215758 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555503 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCc1cc2ccccc2o1 InChI=1S/C23H24N2O5/c26-20(22(28)24-14-17-13-16-9-4-5-11-19(16)30-17)21(27)23(29)25-12-6-10-18(25)15-7-2-1-3-8-15/h1-5,7-9,11,13,18,20-21,26-27H,6,10,12,14H2,(H,24,28)/t18?,20-,21-/m1/s1 LRRAUDSVXJEODP-VTVVEXCCSA-N 50309153 (2R,3R)-N-(benzofuran-2-ylmethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL591774 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309153&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11517085 104163514 CHEMBL591774 ZINC45337262 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555504 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCCc1cc(Cc2ccccc2)cs1 InChI=1S/C27H30N2O4S/c30-24(25(31)27(33)29-15-7-12-23(29)21-10-5-2-6-11-21)26(32)28-14-13-22-17-20(18-34-22)16-19-8-3-1-4-9-19/h1-6,8-11,17-18,23-25,30-31H,7,12-16H2,(H,28,32)/t23?,24-,25-/m1/s1 YYPITAAWUASTAE-OPWSDZRHSA-N 50309154 (2R,3R)-N-(2-(4-benzylthiophen-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL602949 Disintegrin and metalloproteinase domain-containing protein 17 66 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309154 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309154&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46184724 104163515 CHEMBL602949 ZINC45389638 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555505 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccc(F)cc1)C(=O)NCc1cc(Cc2ccccc2)cs1 InChI=1S/C26H27FN2O4S/c27-20-10-8-19(9-11-20)22-7-4-12-29(22)26(33)24(31)23(30)25(32)28-15-21-14-18(16-34-21)13-17-5-2-1-3-6-17/h1-3,5-6,8-11,14,16,22-24,30-31H,4,7,12-13,15H2,(H,28,32)/t22?,23-,24-/m1/s1 OZJLYYLVVVZYFG-HEYJASKDSA-N 50309155 (2R,3R)-N-((4-benzylthiophen-2-yl)methyl)-4-(2-(4-fluorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL591590 Disintegrin and metalloproteinase domain-containing protein 17 93 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309155&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229836 104163516 CHEMBL591590 ZINC45336160 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555506 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(Cc2ccccc2)cc1 InChI=1S/C28H29ClN2O4/c29-23-9-4-8-22(17-23)24-10-5-15-31(24)28(35)26(33)25(32)27(34)30-18-21-13-11-20(12-14-21)16-19-6-2-1-3-7-19/h1-4,6-9,11-14,17,24-26,32-33H,5,10,15-16,18H2,(H,30,34)/t24?,25-,26-/m1/s1 OELMDIRJWGQCSO-KPRFIHOGSA-N 50309156 (2R,3R)-N-(4-benzylbenzyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL601735 Disintegrin and metalloproteinase domain-containing protein 17 70 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309156&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229837 104163517 CHEMBL601735 ZINC45372645 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555507 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCCc1nc(Cc2ccccc2)cs1 InChI=1S/C26H29N3O4S/c30-23(24(31)26(33)29-15-7-12-21(29)19-10-5-2-6-11-19)25(32)27-14-13-22-28-20(17-34-22)16-18-8-3-1-4-9-18/h1-6,8-11,17,21,23-24,30-31H,7,12-16H2,(H,27,32)/t21?,23-,24-/m1/s1 SHZDQGUSESIWNW-MXNGKVSJSA-N 50309157 (2R,3R)-N-(2-(4-benzylthiazol-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL591591 Disintegrin and metalloproteinase domain-containing protein 17 48 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309157&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229838 104163518 CHEMBL591591 ZINC45336167 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555508 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCc1nc(Cc2ccccc2)cs1 InChI=1S/C25H27N3O4S/c29-22(23(30)25(32)28-13-7-12-20(28)18-10-5-2-6-11-18)24(31)26-15-21-27-19(16-33-21)14-17-8-3-1-4-9-17/h1-6,8-11,16,20,22-23,29-30H,7,12-15H2,(H,26,31)/t20?,22-,23-/m1/s1 IAGWKUXWVBSITQ-JHRSTNGLSA-N 50309158 (2R,3R)-N-((4-benzylthiazol-2-yl)methyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL592052 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309158 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309158&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229872 104163519 CHEMBL592052 ZINC45339025 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555509 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCCc1nc(Cc2ccccc2)co1 InChI=1S/C26H29N3O5/c30-23(24(31)26(33)29-15-7-12-21(29)19-10-5-2-6-11-19)25(32)27-14-13-22-28-20(17-34-22)16-18-8-3-1-4-9-18/h1-6,8-11,17,21,23-24,30-31H,7,12-16H2,(H,27,32)/t21?,23-,24-/m1/s1 YASVERJBAKMIAZ-MXNGKVSJSA-N 50309159 (2R,3R)-N-(2-(4-benzyloxazol-2-yl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL607026 Disintegrin and metalloproteinase domain-containing protein 17 461 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309159&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229873 104163520 CHEMBL607026 ZINC45384395 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555510 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCc1nc(Cc2ccccc2)co1 InChI=1S/C25H27N3O5/c29-22(23(30)25(32)28-13-7-12-20(28)18-10-5-2-6-11-18)24(31)26-15-21-27-19(16-33-21)14-17-8-3-1-4-9-17/h1-6,8-11,16,20,22-23,29-30H,7,12-15H2,(H,26,31)/t20?,22-,23-/m1/s1 QKTRJHWCZYNJRL-JHRSTNGLSA-N 50309160 (2R,3R)-N-((4-benzyloxazol-2-yl)methyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)butanamide::CHEMBL592053 Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309160&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229874 104163521 CHEMBL592053 ZINC45339030 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555511 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1cc(CC2C=CC=CC2Cl)cs1 InChI=1S/C26H28Cl2N2O4S/c27-19-7-3-6-18(13-19)22-9-4-10-30(22)26(34)24(32)23(31)25(33)29-14-20-12-16(15-35-20)11-17-5-1-2-8-21(17)28/h1-3,5-8,12-13,15,17,21-24,31-32H,4,9-11,14H2,(H,29,33)/t17?,21?,22-,23-,24-/m1/s1 VTFFMDWYMKICTL-KIFKWCHDSA-N 50309161 (2R,3R)-N-((4-((6-chlorocyclohexa-2,4-dienyl)methyl)thiophen-2-yl)methyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL591031 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309161&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229924 104163522 CHEMBL591031 ZINC49746004 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555512 O[C@H]([C@@H](O)C(=S)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1cc(Cc2ccccc2Cl)cs1 InChI=1S/C26H26Cl2N2O3S2/c27-19-7-3-6-18(13-19)22-9-4-10-30(22)26(34)24(32)23(31)25(33)29-14-20-12-16(15-35-20)11-17-5-1-2-8-21(17)28/h1-3,5-8,12-13,15,22-24,31-32H,4,9-11,14H2,(H,29,33)/t22?,23-,24-/m1/s1 BWBDNOPTZINBCC-HEYJASKDSA-N 50309162 (2R,3R)-N-((4-(2-chlorobenzyl)thiophen-2-yl)methyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-thioxobutanamide::CHEMBL602943 Disintegrin and metalloproteinase domain-containing protein 17 1520 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309162&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229925 104163523 CHEMBL602943 ZINC49767011 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555513 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=S)NCc1cc(Cc2ccccc2Cl)cs1 InChI=1S/C26H26Cl2N2O3S2/c27-19-7-3-6-18(13-19)22-9-4-10-30(22)26(33)24(32)23(31)25(34)29-14-20-12-16(15-35-20)11-17-5-1-2-8-21(17)28/h1-3,5-8,12-13,15,22-24,31-32H,4,9-11,14H2,(H,29,34)/t22?,23-,24-/m1/s1 JSIYSTAUNNEYIT-HEYJASKDSA-N 50309163 (2R,3R)-N-((4-(2-chlorobenzyl)thiophen-2-yl)methyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanethioamide::CHEMBL591032 Disintegrin and metalloproteinase domain-containing protein 17 1110 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309163&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229926 104163524 CHEMBL591032 ZINC49746009 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555514 O[C@H]([C@@H](O)c1nccs1)C(=O)NCCc1cccs1 InChI=1S/C12H14N2O3S2/c15-9(10(16)12-14-5-7-19-12)11(17)13-4-3-8-2-1-6-18-8/h1-2,5-7,9-10,15-16H,3-4H2,(H,13,17)/t9-,10-/m1/s1 VAWVEYBFYPKNPQ-NXEZZACHSA-N 50309164 (2R,3R)-2,3-dihydroxy-3-(thiazol-2-yl)-N-(2-(thiophen-2-yl)ethyl)propanamide::CHEMBL590314 Disintegrin and metalloproteinase domain-containing protein 17 5530 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309164&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229976 104163525 CHEMBL590314 ZINC45336913 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555515 Cn1ccnc1[C@H](O)[C@@H](O)C(=O)NCCc1cccs1 InChI=1S/C13H17N3O3S/c1-16-7-6-14-12(16)10(17)11(18)13(19)15-5-4-9-3-2-8-20-9/h2-3,6-8,10-11,17-18H,4-5H2,1H3,(H,15,19)/t10-,11-/m1/s1 ZDHSDBBVHNKWTR-GHMZBOCLSA-N 50309165 (2R,3S)-2,3-dihydroxy-3-(1-methyl-1H-imidazol-2-yl)-N-(2-(thiophen-2-yl)ethyl)propanamide::CHEMBL603133 Disintegrin and metalloproteinase domain-containing protein 17 10600 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309165 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309165&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229977 104163526 CHEMBL603133 ZINC45391439 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555546 O[C@H]([C@@H](O)C(=O)N1CCCC1c1ccccc1)C(=O)NCCc1cccs1 InChI=1S/C20H24N2O4S/c23-17(19(25)21-11-10-15-8-5-13-27-15)18(24)20(26)22-12-4-9-16(22)14-6-2-1-3-7-14/h1-3,5-8,13,16-18,23-24H,4,9-12H2,(H,21,25)/t16?,17-,18-/m1/s1 YOFBZNUFKLZQNH-UKKPGEIXSA-N 50309166 (2R,3R)-2,3-dihydroxy-4-oxo-4-(2-phenylpyrrolidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL609563 Disintegrin and metalloproteinase domain-containing protein 17 96 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309166&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11567255 104163527 CHEMBL609563 ZINC35826385 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555547 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCCc1cccs1 InChI=1S/C20H24N2O4S/c23-17(19(25)21-11-10-15-8-5-13-27-15)18(24)20(26)22-12-4-9-16(22)14-6-2-1-3-7-14/h1-3,5-8,13,16-18,23-24H,4,9-12H2,(H,21,25)/t16-,17-,18-/m1/s1 YOFBZNUFKLZQNH-KZNAEPCWSA-N 50309167 (2R,3R)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL603238 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309167&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230412 104163528 CHEMBL603238 ZINC35826385 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555548 O[C@H]([C@@H](O)C(=O)N1CCC[C@H]1c1ccccc1)C(=O)NCCc1cccs1 InChI=1S/C20H24N2O4S/c23-17(19(25)21-11-10-15-8-5-13-27-15)18(24)20(26)22-12-4-9-16(22)14-6-2-1-3-7-14/h1-3,5-8,13,16-18,23-24H,4,9-12H2,(H,21,25)/t16-,17+,18+/m0/s1 YOFBZNUFKLZQNH-RCCFBDPRSA-N 50309168 (2R,3R)-2,3-dihydroxy-4-oxo-4-((S)-2-phenylpyrrolidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL597719 Disintegrin and metalloproteinase domain-containing protein 17 725 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309168&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230413 104163529 CHEMBL597719 ZINC35826384 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566902 CC(=O)NCC[C@@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)C(=O)NO InChI=1S/C18H21N3O5S/c1-13(22)19-12-11-17(18(23)20-24)21-27(25,26)16-9-7-15(8-10-16)14-5-3-2-4-6-14/h2-10,17,21,24H,11-12H2,1H3,(H,19,22)(H,20,23)/t17-/m1/s1 RLHOCYLKSSHKMW-QGZVFWFLSA-N 50314225 (R)-4-acetamido-2-(biphenyl-4-ylsulfonamido)-N-hydroxybutanamide::CHEMBL1090647 Disintegrin and metalloproteinase domain-containing protein 17 300 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314225&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45380190 104148586 CHEMBL1090647 ZINC49089777 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566908 CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C17H20N2O5S/c1-13(2)24-19(12-17(20)18-21)25(22,23)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,21H,12H2,1-2H3,(H,18,20) PHGLPDURIUEELR-UHFFFAOYSA-N 50161331 2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydroxy-acetamide::CHEMBL181244::N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)acetamide Disintegrin and metalloproteinase domain-containing protein 17 120000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161331 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161331&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10B 4H76,4H3X 10044321 104047647 CHEMBL181244 5140 ZINC03818628 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566913 CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C18H22N2O4S/c1-14(2)12-20(13-18(21)19-22)25(23,24)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14,22H,12-13H2,1-2H3,(H,19,21) PZJJOMPTIHBGHO-UHFFFAOYSA-N 50294119 CHEMBL561625::N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)acetamide Disintegrin and metalloproteinase domain-containing protein 17 53000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294119 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294119&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45269631 104135670 CHEMBL561625 ZINC43073695 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566918 ONC(=O)CNS(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C14H14N2O4S/c17-14(16-18)10-15-21(19,20)13-8-6-12(7-9-13)11-4-2-1-3-5-11/h1-9,15,18H,10H2,(H,16,17) NKGRTRASISLCCZ-UHFFFAOYSA-N 50294120 2-(biphenyl-4-ylsulfonamido)-N-hydroxyacetamide::CHEMBL550148 Disintegrin and metalloproteinase domain-containing protein 17 2400 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50294120 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50294120&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search HS4 3F17 25049753 104135671 CHEMBL550148 ZINC43014847 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566923 COc1ccc(cc1)S(=O)(=O)N(CC(=O)NO)OC(C)C InChI=1S/C12H18N2O6S/c1-9(2)20-14(8-12(15)13-16)21(17,18)11-6-4-10(19-3)5-7-11/h4-7,9,16H,8H2,1-3H3,(H,13,15) ICISPHGVMHWYTI-UHFFFAOYSA-N 50204371 2-{isopropoxy[(4-methoxyphenyl)sulfonyl]amino}-N-hydroxyacetamide::CHEMBL226439::N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonamido)acetamide Disintegrin and metalloproteinase domain-containing protein 17 180000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204371 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204371&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44423677 104083071 CHEMBL226439 ZINC28647443 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566928 COc1ccc(cc1)S(=O)(=O)N(CC(C)C)CC(=O)NO InChI=1S/C13H20N2O5S/c1-10(2)8-15(9-13(16)14-17)21(18,19)12-6-4-11(20-3)5-7-12/h4-7,10,17H,8-9H2,1-3H3,(H,14,16) JIRXORZYIXSWOB-UHFFFAOYSA-N 13080 CGS 27023A Analog 3::N-hydroxy-2-[(4-methoxybenzene)(2-methylpropyl)sulfonamido]acetamide Disintegrin and metalloproteinase domain-containing protein 17 2300 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13080 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13080&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search NGH 1RMZ,4DPE,2JNP,5LAB,4JA1,1Z3J,1Q3A,4G9L,1YCM,2JSD 448002 46513497 DB08271 ZINC03818629 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566933 COc1ccc(cc1)S(=O)(=O)NCC(=O)NO InChI=1S/C9H12N2O5S/c1-16-7-2-4-8(5-3-7)17(14,15)10-6-9(12)11-13/h2-5,10,13H,6H2,1H3,(H,11,12) WLZISXXOYYGJNT-UHFFFAOYSA-N 11328 CHEMBL83508::Hydroxamate 9::N-hydroxy-2-[(4-methoxybenzene)sulfonamido]acetamide Disintegrin and metalloproteinase domain-containing protein 17 1800 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11328 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11328&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search Z79 3LK8,3OHO 10445302 46511873 CHEMBL83508 ZINC10450351 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566938 ONC(=O)CNS(=O)(=O)c1ccc(Br)cc1 InChI=1S/C8H9BrN2O4S/c9-6-1-3-7(4-2-6)16(14,15)10-5-8(12)11-13/h1-4,10,13H,5H2,(H,11,12) AKOBMMAQXVKOJR-UHFFFAOYSA-N 50314226 2-(4-bromophenylsulfonamido)-N-hydroxyacetamide::CHEMBL1090283 Disintegrin and metalloproteinase domain-containing protein 17 3900 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314226&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22004198 104148587 CHEMBL1090283 ZINC49070745 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566943 COc1ccc(cc1)S(=O)(=O)N(OC(C)C)[C@H](C(C)C)C(=O)NO InChI=1S/C15H24N2O6S/c1-10(2)14(15(18)16-19)17(23-11(3)4)24(20,21)13-8-6-12(22-5)7-9-13/h6-11,14,19H,1-5H3,(H,16,18)/t14-/m1/s1 BBUAWDNXWDAMGY-CQSZACIVSA-N 50314227 (R)-N-hydroxy-2-(N-isopropoxy-4-methoxyphenylsulfonamido)-3-methylbutanamide::CHEMBL1090035 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314227&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45380188 104148588 CHEMBL1090035 ZINC28647453 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566948 COc1ccc(cc1)S(=O)(=O)N(CC(C)C)[C@H](C(C)C)C(=O)NO InChI=1S/C16H26N2O5S/c1-11(2)10-18(15(12(3)4)16(19)17-20)24(21,22)14-8-6-13(23-5)7-9-14/h6-9,11-12,15,20H,10H2,1-5H3,(H,17,19)/t15-/m1/s1 KLOYCYLPVRADHA-OAHLLOKOSA-N 50314228 (R)-N-hydroxy-2-(N-isobutyl-4-methoxyphenylsulfonamido)-3-methylbutanamide::CHEMBL1090284 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1021/jm901868z 10.7270/Q26H4HK0 20180536 Nuti, E; Casalini, F; Avramova, SI; Santamaria, S; Fabbi, M; Ferrini, S; Marinelli, L; La Pietra, V; Limongelli, V; Novellino, E; Cercignani, G; Orlandini, E; Nencetti, S; Rossello, A Universit£ di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314228&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45380189 104148589 CHEMBL1090284 ZINC49048822 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555549 O[C@H]([C@@H](O)C(=O)N1CCC(C1)c1ccccc1)C(=O)NCCc1cccs1 InChI=1S/C20H24N2O4S/c23-17(19(25)21-10-8-16-7-4-12-27-16)18(24)20(26)22-11-9-15(13-22)14-5-2-1-3-6-14/h1-7,12,15,17-18,23-24H,8-11,13H2,(H,21,25)/t15?,17-,18-/m1/s1 MXXIVLDAVSWDON-HSFDIDPMSA-N 50309169 (2R,3R)-2,3-dihydroxy-4-oxo-4-(3-phenylpyrrolidin-1-yl)-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL596906 Disintegrin and metalloproteinase domain-containing protein 17 456 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309169&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11710815 104163530 CHEMBL596906 ZINC34635570 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555550 O[C@H]([C@@H](O)C(=O)N1CCc2ccccc2C1)C(=O)NCCc1cccs1 InChI=1S/C19H22N2O4S/c22-16(18(24)20-9-7-15-6-3-11-26-15)17(23)19(25)21-10-8-13-4-1-2-5-14(13)12-21/h1-6,11,16-17,22-23H,7-10,12H2,(H,20,24)/t16-,17-/m1/s1 GFBPBUYOHJVQEQ-IAGOWNOFSA-N 50309170 (2R,3R)-4-(3,4-dihydroisoquinolin-2(1H)-yl)-2,3-dihydroxy-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL599155 Disintegrin and metalloproteinase domain-containing protein 17 91 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309170&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46230471 104163531 CHEMBL599155 ZINC45366385 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50555551 O[C@H]([C@@H](O)C(=O)N1Cc2ccccc2C1)C(=O)NCCc1cccs1 InChI=1S/C18H20N2O4S/c21-15(17(23)19-8-7-14-6-3-9-25-14)16(22)18(24)20-10-12-4-1-2-5-13(12)11-20/h1-6,9,15-16,21-22H,7-8,10-11H2,(H,19,23)/t15-,16-/m1/s1 JSIXTKHHAJBPQT-HZPDHXFCSA-N 50309171 (2R,3R)-2,3-dihydroxy-4-(isoindolin-2-yl)-4-oxo-N-(2-(thiophen-2-yl)ethyl)butanamide::CHEMBL603832 Disintegrin and metalloproteinase domain-containing protein 17 66 ChEMBL 10.1016/j.bmcl.2009.12.004 10.7270/Q2BK1CFB 20022498 Rosner, KE; Guo, Z; Orth, P; Shipps, GW; Belanger, DB; Chan, TY; Curran, PJ; Dai, C; Deng, Y; Girijavallabhan, VM; Hong, L; Lavey, BJ; Lee, JF; Li, D; Liu, Z; Popovici-Muller, J; Ting, PC; Vaccaro, H; Wang, L; Wang, T; Yu, W; Zhou, G; Niu, X; Sun, J; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Arshad Siddiqui, M; Strickland, CO Schering-Plough Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309171&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11566672 104163532 CHEMBL603832 ZINC35825708 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565977 COc1ccc2[nH]n(CC3(C)NC(=O)NC3=O)c(=O)c2c1 InChI=1S/C13H14N4O4/c1-13(11(19)14-12(20)15-13)6-17-10(18)8-5-7(21-2)3-4-9(8)16-17/h3-5,16H,6H2,1-2H3,(H2,14,15,19,20) PIEMRKVLYXWKFP-UHFFFAOYSA-N 50313818 5-((5-methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-methylimidazolidine-2,4-dione::CHEMBL1078396 Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313818&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 724 3L0V 11716217 104148179 CHEMBL1078396 ZINC34639608 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565978 COc1ccc2c(c1)[nH]n(CC1(C)NC(=O)NC1=O)c2=O InChI=1S/C13H14N4O4/c1-13(11(19)14-12(20)15-13)6-17-10(18)8-4-3-7(21-2)5-9(8)16-17/h3-5,16H,6H2,1-2H3,(H2,14,15,19,20) WPXNJYBHOLRDHG-UHFFFAOYSA-N 50313819 5-((6-methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-methylimidazolidine-2,4-dione::CHEMBL1078397 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313819&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11630678 104148180 CHEMBL1078397 ZINC35964104 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565979 CCOc1ccc2[nH]n(CC3(C)NC(=O)NC3=O)c(=O)c2c1 InChI=1S/C14H16N4O4/c1-3-22-8-4-5-10-9(6-8)11(19)18(17-10)7-14(2)12(20)15-13(21)16-14/h4-6,17H,3,7H2,1-2H3,(H2,15,16,20,21) VHMRFOPHQUZVGY-UHFFFAOYSA-N 50313820 5-((5-ethoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-methylimidazolidine-2,4-dione::CHEMBL1078398 Disintegrin and metalloproteinase domain-containing protein 17 209 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313820&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11695181 104148181 CHEMBL1078398 ZINC38265715 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565980 CC1(Cn2[nH]c3ccc(OCc4ccccc4)cc3c2=O)NC(=O)NC1=O InChI=1S/C19H18N4O4/c1-19(17(25)20-18(26)21-19)11-23-16(24)14-9-13(7-8-15(14)22-23)27-10-12-5-3-2-4-6-12/h2-9,22H,10-11H2,1H3,(H2,20,21,25,26) MTMCABVIUPBASP-UHFFFAOYSA-N 50313821 5-((5-(benzyloxy)-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-methylimidazolidine-2,4-dione::CHEMBL1087795 Disintegrin and metalloproteinase domain-containing protein 17 391 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313821&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11552350 104148182 CHEMBL1087795 ZINC35791837 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565981 CC1(Cn2[nH]c3cc(OCc4ccccc4)ccc3c2=O)NC(=O)NC1=O InChI=1S/C19H18N4O4/c1-19(17(25)20-18(26)21-19)11-23-16(24)14-8-7-13(9-15(14)22-23)27-10-12-5-3-2-4-6-12/h2-9,22H,10-11H2,1H3,(H2,20,21,25,26) YLNUUCGXIVYTDQ-UHFFFAOYSA-N 50313822 5-((6-(benzyloxy)-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-methylimidazolidine-2,4-dione::CHEMBL1087291 Disintegrin and metalloproteinase domain-containing protein 17 100 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313822&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11639207 104148183 CHEMBL1087291 ZINC35982893 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565982 COc1cc2[nH]n(CC3(NC(=O)NC3=O)c3ccccc3)c(=O)c2cc1OC InChI=1S/C19H18N4O5/c1-27-14-8-12-13(9-15(14)28-2)22-23(16(12)24)10-19(11-6-4-3-5-7-11)17(25)20-18(26)21-19/h3-9,22H,10H2,1-2H3,(H2,20,21,25,26) SHEYYOPIWRPHLH-UHFFFAOYSA-N 50313823 5-((5,6-dimethoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-phenylimidazolidine-2,4-dione::CHEMBL1087292 Disintegrin and metalloproteinase domain-containing protein 17 53 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313823&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11646633 104148184 CHEMBL1087292 ZINC35996768 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565983 COc1ccc2[nH]n(CC3(NC(=O)NC3=O)c3ccccc3)c(=O)c2c1 InChI=1S/C18H16N4O4/c1-26-12-7-8-14-13(9-12)15(23)22(21-14)10-18(11-5-3-2-4-6-11)16(24)19-17(25)20-18/h2-9,21H,10H2,1H3,(H2,19,20,24,25) OXEVTLWXFDHNQD-UHFFFAOYSA-N 50313824 5-((5-methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-phenylimidazolidine-2,4-dione::CHEMBL1087293 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313824&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 727 3LE9 11566516 104148185 CHEMBL1087293 ZINC35825536 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565984 Fc1ccc(cc1)C1(CN2Cc3ccccc3C2=O)NC(=O)NC1=O InChI=1S/C18H14FN3O3/c19-13-7-5-12(6-8-13)18(16(24)20-17(25)21-18)10-22-9-11-3-1-2-4-14(11)15(22)23/h1-8H,9-10H2,(H2,20,21,24,25) JXRAVILGJNFJFT-UHFFFAOYSA-N 50313825 (+/-)-5-(4-fluorophenyl)-5-((1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1087294 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313825 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313825&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881430 104148186 CHEMBL1087294 ZINC49049004 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565985 Fc1ccc(cc1)C1(CN2Cc3ccccc3S2(=O)=O)NC(=O)NC1=O InChI=1S/C17H14FN3O4S/c18-13-7-5-12(6-8-13)17(15(22)19-16(23)20-17)10-21-9-11-3-1-2-4-14(11)26(21,24)25/h1-8H,9-10H2,(H2,19,20,22,23) NCEBBHOMOAWRPQ-UHFFFAOYSA-N 50313826 (+/-)-5-(1,1-Dioxo-1,3-dihydro-1lambda*6*-benzo[d]isothiazol-2-ylmethyl)-5-(4-fluoro-phenyl)-imidazolidine-2,4-dione::CHEMBL1087930 Disintegrin and metalloproteinase domain-containing protein 17 1048 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313826 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313826&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881486 104148187 CHEMBL1087930 ZINC49050044 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565986 Fc1ccc(cc1)C1(CN2CC3CCCCN3C2=O)NC(=O)NC1=O InChI=1S/C17H19FN4O3/c18-12-6-4-11(5-7-12)17(14(23)19-15(24)20-17)10-21-9-13-3-1-2-8-22(13)16(21)25/h4-7,13H,1-3,8-10H2,(H2,19,20,23,24) UKGIAXIYHPXKEB-UHFFFAOYSA-N 50313827 (+/-)-5-(4-fluorophenyl)-5-((3-oxotetrahydroimidazo[1,5-a]pyridin-2(1H,3H,5H)-yl)methyl)imidazolidine-2,4-dione::CHEMBL1087931 Disintegrin and metalloproteinase domain-containing protein 17 2729 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313827 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313827&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881487 104148188 CHEMBL1087931 ZINC49050529 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565987 Fc1ccc(cc1)C1(CN2CC3CCCN3C2=O)NC(=O)NC1=O InChI=1S/C16H17FN4O3/c17-11-5-3-10(4-6-11)16(13(22)18-14(23)19-16)9-20-8-12-2-1-7-21(12)15(20)24/h3-6,12H,1-2,7-9H2,(H2,18,19,22,23) RAEHZADZKOMXFG-UHFFFAOYSA-N 50313828 (+/-)-5-(4-fluorophenyl)-5-((3-oxo-1H-pyrrolo[1,2-c]imidazol-2(3H,5H,6H,7H,7aH)-yl)methyl)imidazolidine-2,4-dione::CHEMBL1087932 Disintegrin and metalloproteinase domain-containing protein 17 >50000 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313828 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313828&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881488 104148189 CHEMBL1087932 ZINC49126069 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565988 CC1(CN2Cc3cccnc3C2=O)NC(=O)NC1=O InChI=1S/C12H12N4O3/c1-12(10(18)14-11(19)15-12)6-16-5-7-3-2-4-13-8(7)9(16)17/h2-4H,5-6H2,1H3,(H2,14,15,18,19) UJIPOPYBPYUDID-UHFFFAOYSA-N 50313829 (+/-)-5-methyl-5-((7-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methyl)imidazolidine-2,4-dione::CHEMBL1077188 Disintegrin and metalloproteinase domain-containing protein 17 4818 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313829 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313829&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24873166 104148190 CHEMBL1077188 ZINC49525747 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565989 CC1(Cn2cc3[nH]cccc3c2=O)NC(=O)NC1=O InChI=1S/C12H12N4O3/c1-12(10(18)14-11(19)15-12)6-16-5-8-7(9(16)17)3-2-4-13-8/h2-5,13H,6H2,1H3,(H2,14,15,18,19) MMIDLGONVCYQIC-UHFFFAOYSA-N 50313830 (+/-)-5-methyl-5-((5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methyl)imidazolidine-2,4-dione::CHEMBL1087303 Disintegrin and metalloproteinase domain-containing protein 17 24900 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313830 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313830&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881489 104148191 CHEMBL1087303 ZINC49112906 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565990 COc1cc2C(=O)N(CC3(NC(=O)NC3=O)c3ccc(F)cc3)Cc2cn1 InChI=1S/C18H15FN4O4/c1-27-14-6-13-10(7-20-14)8-23(15(13)24)9-18(16(25)21-17(26)22-18)11-2-4-12(19)5-3-11/h2-7H,8-9H2,1H3,(H2,21,22,25,26) IVWBDVJIUHIJFU-UHFFFAOYSA-N 50313831 (+/-)-5-(4-fluorophenyl)-5-((6-methoxy-1-oxo-1H-pyrrolo[3,4-c]pyridin-2(3H)-yl)methyl)imidazolidine-2,4-dione::CHEMBL1087430 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313831 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313831&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24873286 104148192 CHEMBL1087430 ZINC49113227 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565991 COc1ccc2CN(CC3(C)NC(=O)NC3=O)C(=O)c2c1 InChI=1S/C14H15N3O4/c1-14(12(19)15-13(20)16-14)7-17-6-8-3-4-9(21-2)5-10(8)11(17)18/h3-5H,6-7H2,1-2H3,(H2,15,16,19,20) BMHLDTHLHCGSBB-UHFFFAOYSA-N 50313832 (+/-)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-methylimidazolidine-2,4-dione::CHEMBL1088216 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313832 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313832&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24888678 104148193 CHEMBL1088216 ZINC49112047 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565992 CC[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O InChI=1S/C15H17N3O4/c1-3-15(13(20)16-14(21)17-15)8-18-7-9-4-5-10(22-2)6-11(9)12(18)19/h4-6H,3,7-8H2,1-2H3,(H2,16,17,20,21)/t15-/m1/s1 QRPAYWXNSPFKBS-OAHLLOKOSA-N 50313833 (R)-5-ethyl-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1084659 Disintegrin and metalloproteinase domain-containing protein 17 56 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313833 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313833&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881520 104148194 CHEMBL1084659 ZINC49046230 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565993 COc1ccc2CN(C[C@@]3(Cc4ccccc4)NC(=O)NC3=O)C(=O)c2c1 InChI=1S/C20H19N3O4/c1-27-15-8-7-14-11-23(17(24)16(14)9-15)12-20(18(25)21-19(26)22-20)10-13-5-3-2-4-6-13/h2-9H,10-12H2,1H3,(H2,21,22,25,26)/t20-/m1/s1 XQJIQAROKXQYLV-HXUWFJFHSA-N 50313834 (R)-5-benzyl-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1084660 Disintegrin and metalloproteinase domain-containing protein 17 >500 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313834 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313834&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881521 104148195 CHEMBL1084660 ZINC49037166 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565994 COc1ccc2CN(CC3(NC(=O)NC3=O)c3ccccc3)C(=O)c2c1 InChI=1S/C19H17N3O4/c1-26-14-8-7-12-10-22(16(23)15(12)9-14)11-19(13-5-3-2-4-6-13)17(24)20-18(25)21-19/h2-9H,10-11H2,1H3,(H2,20,21,24,25) NNUDSTKYGPKRGA-UHFFFAOYSA-N 50313835 (+/-)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-phenylimidazolidine-2,4-dione::CHEMBL1084661 Disintegrin and metalloproteinase domain-containing protein 17 3.3 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313835 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313835&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881522 104148196 CHEMBL1084661 ZINC49046238 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565995 Oc1ccccc1C1(CN2Cc3ccc(F)cc3C2=O)NC(=O)NC1=O InChI=1S/C18H14FN3O4/c19-11-6-5-10-8-22(15(24)12(10)7-11)9-18(16(25)20-17(26)21-18)13-3-1-2-4-14(13)23/h1-7,23H,8-9H2,(H2,20,21,25,26) JCJNPNRZJNFMTI-UHFFFAOYSA-N 50313836 (+/-)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(2-hydroxyphenyl)imidazolidine-2,4-dione::CHEMBL1084904 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313836 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313836&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881523 104148197 CHEMBL1084904 ZINC49036872 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565996 Oc1cccc(c1)C1(CN2Cc3ccc(Cl)cc3C2=O)NC(=O)NC1=O InChI=1S/C18H14ClN3O4/c19-12-5-4-10-8-22(15(24)14(10)7-12)9-18(16(25)20-17(26)21-18)11-2-1-3-13(23)6-11/h1-7,23H,8-9H2,(H2,20,21,25,26) AKULJWUXTVBMJD-UHFFFAOYSA-N 50313837 (+/-)-5-((6-chloro-1-oxoisoindolin-2-yl)methyl)-5-(3-hydroxyphenyl)imidazolidine-2,4-dione::CHEMBL1090735 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313837 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313837&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881568 104148198 CHEMBL1090735 ZINC49070258 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565997 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(O)cc3)C(=O)c2c1 InChI=1S/C19H17N3O5/c1-27-14-7-2-11-9-22(16(24)15(11)8-14)10-19(17(25)20-18(26)21-19)12-3-5-13(23)6-4-12/h2-8,23H,9-10H2,1H3,(H2,20,21,25,26)/t19-/m0/s1 KYZRENMUIQDTHR-IBGZPJMESA-N 50313838 (R)-5-(4-hydroxyphenyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1090736 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313838 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313838&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881569 104148199 CHEMBL1090736 ZINC49125439 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565998 Fc1ccc(cc1)[C@]1(CN2Cc3ccc(Cl)cc3C2=O)NC(=O)NC1=O InChI=1S/C18H13ClFN3O3/c19-12-4-1-10-8-23(15(24)14(10)7-12)9-18(16(25)21-17(26)22-18)11-2-5-13(20)6-3-11/h1-7H,8-9H2,(H2,21,22,25,26)/t18-/m0/s1 CNUCYIDHDPTDOD-SFHVURJKSA-N 50313839 (R)-5-((6-chloro-1-oxoisoindolin-2-yl)methyl)-5-(4-fluorophenyl)imidazolidine-2,4-dione::CHEMBL1077203 Disintegrin and metalloproteinase domain-containing protein 17 0.400000 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313839 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313839&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46844314 104148200 CHEMBL1077203 ZINC43105138 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50565999 Fc1ccc(c(F)c1)C1(CN2Cc3ccc(Cl)cc3C2=O)NC(=O)NC1=O InChI=1S/C18H12ClF2N3O3/c19-10-2-1-9-7-24(15(25)12(9)5-10)8-18(16(26)22-17(27)23-18)13-4-3-11(20)6-14(13)21/h1-6H,7-8H2,(H2,22,23,26,27) AJJKDXWYFPYPSE-UHFFFAOYSA-N 50313840 (+/-)-5-((6-chloro-1-oxoisoindolin-2-yl)methyl)-5-(2,4-difluorophenyl)imidazolidine-2,4-dione::CHEMBL1089041 Disintegrin and metalloproteinase domain-containing protein 17 5.5 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313840 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313840&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11668295 104148201 CHEMBL1089041 ZINC38215514 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566000 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(F)cc3)C(=O)c2c1 InChI=1S/C19H16FN3O4/c1-27-14-7-2-11-9-23(16(24)15(11)8-14)10-19(17(25)21-18(26)22-19)12-3-5-13(20)6-4-12/h2-8H,9-10H2,1H3,(H2,21,22,25,26)/t19-/m0/s1 YMUVKSFBWOSBKG-IBGZPJMESA-N 50313841 (R)-5-(4-fluorophenyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1089042 Disintegrin and metalloproteinase domain-containing protein 17 0.800000 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313841&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46845559 104148202 CHEMBL1089042 ZINC49066938 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566001 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3cnccn3)C(=O)c2c1 InChI=1S/C17H15N5O4/c1-26-11-3-2-10-8-22(14(23)12(10)6-11)9-17(13-7-18-4-5-19-13)15(24)20-16(25)21-17/h2-7H,8-9H2,1H3,(H2,20,21,24,25)/t17-/m0/s1 NNWAOWAMVGAOSU-KRWDZBQOSA-N 50313842 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(pyrazin-2-yl)imidazolidine-2,4-dione::CHEMBL1077216 Disintegrin and metalloproteinase domain-containing protein 17 0.700000 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313842 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313842&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881608 104148203 CHEMBL1077216 ZINC49525757 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566002 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccco3)C(=O)c2c1 InChI=1S/C17H15N3O5/c1-24-11-5-4-10-8-20(14(21)12(10)7-11)9-17(13-3-2-6-25-13)15(22)18-16(23)19-17/h2-7H,8-9H2,1H3,(H2,18,19,22,23)/t17-/m0/s1 XXKBGJSOWWMEIT-KRWDZBQOSA-N 50313843 (R)-5-(furan-2-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1092505 Disintegrin and metalloproteinase domain-containing protein 17 0.700000 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313843 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313843&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881609 104148204 CHEMBL1092505 ZINC49070648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566003 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3cnn(C)c3)C(=O)c2c1 InChI=1S/C17H17N5O4/c1-21-8-11(6-18-21)17(15(24)19-16(25)20-17)9-22-7-10-3-4-12(26-2)5-13(10)14(22)23/h3-6,8H,7,9H2,1-2H3,(H2,19,20,24,25)/t17-/m0/s1 KFLZPQZYYHUBAI-KRWDZBQOSA-N 50313844 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(1-methyl-1H-pyrazol-4-yl)imidazolidine-2,4-dione::CHEMBL1089727 Disintegrin and metalloproteinase domain-containing protein 17 1.1 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313844 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313844&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881610 104148205 CHEMBL1089727 ZINC49066551 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566004 COc1ccc2C(=O)N(CC3(NC(=O)NC3=O)c3ccccc3)Cc2c1 InChI=1S/C19H17N3O4/c1-26-14-7-8-15-12(9-14)10-22(16(15)23)11-19(13-5-3-2-4-6-13)17(24)20-18(25)21-19/h2-9H,10-11H2,1H3,(H2,20,21,24,25) BBWGZCJZNXEKGH-UHFFFAOYSA-N 50313845 (+/-)-5-((5-methoxy-1-oxoisoindolin-2-yl)methyl)-5-phenylimidazolidine-2,4-dione::CHEMBL1089728 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313845 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313845&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11653224 104148206 CHEMBL1089728 ZINC35790575 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566005 Oc1ccc2C(=O)N(C[C@]3(NC(=O)NC3=O)c3ccc(F)cc3)Cc2c1 InChI=1S/C18H14FN3O4/c19-12-3-1-11(2-4-12)18(16(25)20-17(26)21-18)9-22-8-10-7-13(23)5-6-14(10)15(22)24/h1-7,23H,8-9H2,(H2,20,21,25,26)/t18-/m0/s1 FSTVBTPVQKBNHI-SFHVURJKSA-N 50313846 (R)-5-(4-fluorophenyl)-5-((5-hydroxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1090059 Disintegrin and metalloproteinase domain-containing protein 17 0.500000 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313846 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313846&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881611 104148207 CHEMBL1090059 ZINC43105141 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566006 Fc1ccc(cc1)C1(CN2Cc3cc(Cl)ccc3C2=O)NC(=O)NC1=O InChI=1S/C18H13ClFN3O3/c19-12-3-6-14-10(7-12)8-23(15(14)24)9-18(16(25)21-17(26)22-18)11-1-4-13(20)5-2-11/h1-7H,8-9H2,(H2,21,22,25,26) JBUMSXZQHQQUPH-UHFFFAOYSA-N 50313847 (+/-)-5-((5-chloro-1-oxoisoindolin-2-yl)methyl)-5-(4-fluorophenyl)imidazolidine-2,4-dione::CHEMBL1090748 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313847 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313847&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11675173 104148208 CHEMBL1090748 ZINC38224766 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566007 Fc1ccc(cc1)[C@]1(CN2Cc3cc(OCC4CC4)ccc3C2=O)NC(=O)NC1=O InChI=1S/C22H20FN3O4/c23-16-5-3-15(4-6-16)22(20(28)24-21(29)25-22)12-26-10-14-9-17(30-11-13-1-2-13)7-8-18(14)19(26)27/h3-9,13H,1-2,10-12H2,(H2,24,25,28,29)/t22-/m0/s1 KYVWXXDKKKAVDB-QFIPXVFZSA-N 50313848 (R)-5-((5-(cyclopropylmethoxy)-1-oxoisoindolin-2-yl)methyl)-5-(4-fluorophenyl)imidazolidine-2,4-dione::CHEMBL1090749 Disintegrin and metalloproteinase domain-containing protein 17 2.4 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313848 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313848&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881647 104148209 CHEMBL1090749 ZINC49071360 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566008 Fc1ccc(cc1)C1(CN2Cc3cc(OCc4ccncc4)ccc3C2=O)NC(=O)NC1=O InChI=1S/C24H19FN4O4/c25-18-3-1-17(2-4-18)24(22(31)27-23(32)28-24)14-29-12-16-11-19(5-6-20(16)21(29)30)33-13-15-7-9-26-10-8-15/h1-11H,12-14H2,(H2,27,28,31,32) KUGLIACWEJGELJ-UHFFFAOYSA-N 50313849 (+/-)-5-(4-fluorophenyl)-5-((1-oxo-5-(pyridin-4-ylmethoxy)isoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1091095 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313849 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313849&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881648 104148210 CHEMBL1091095 ZINC49070771 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566009 Fc1ccc(cc1)[C@]1(CN2Cc3cc(OCCC4CCCCC4)ccc3C2=O)NC(=O)NC1=O InChI=1S/C26H28FN3O4/c27-20-8-6-19(7-9-20)26(24(32)28-25(33)29-26)16-30-15-18-14-21(10-11-22(18)23(30)31)34-13-12-17-4-2-1-3-5-17/h6-11,14,17H,1-5,12-13,15-16H2,(H2,28,29,32,33)/t26-/m0/s1 GMMGRUXUJDRCEA-SANMLTNESA-N 50313850 (R)-5-((5-(2-cyclohexylethoxy)-1-oxoisoindolin-2-yl)methyl)-5-(4-fluorophenyl)imidazolidine-2,4-dione::CHEMBL1093392 Disintegrin and metalloproteinase domain-containing protein 17 332 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313850 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313850&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881649 104148211 CHEMBL1093392 ZINC49071532 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50566010 Cc1cc(COc2ccc3C(=O)N(CC4(NC(=O)NC4=O)c4ccc(F)cc4)Cc3c2)c2ccccc2n1 InChI=1S/C29H23FN4O4/c1-17-12-19(23-4-2-3-5-25(23)31-17)15-38-22-10-11-24-18(13-22)14-34(26(24)35)16-29(27(36)32-28(37)33-29)20-6-8-21(30)9-7-20/h2-13H,14-16H2,1H3,(H2,32,33,36,37) CXUFMSGHQOMBDY-UHFFFAOYSA-N 50313851 (+/-)-5-(4-fluorophenyl)-5-((5-((2-methylquinolin-4-yl)methoxy)-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1084412 Disintegrin and metalloproteinase domain-containing protein 17 1.7 ChEMBL 10.1016/j.bmcl.2010.01.148 10.7270/Q2F76CQ9 20172725 Yu, W; Guo, Z; Orth, P; Madison, V; Chen, L; Dai, C; Feltz, RJ; Girijavallabhan, VM; Kim, SH; Kozlowski, JA; Lavey, BJ; Li, D; Lundell, D; Niu, X; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Sun, J; Tong, L; Umland, S; Wong, MK; Yang, DY; Zhou, G Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313851 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313851&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46881694 104148212 CHEMBL1084412 ZINC49035025 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50559557 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(s1)-n1cc(Cl)cn1)C(O)=O InChI=1S/C18H16ClN3O4S2/c1-11-16(12-5-3-2-4-6-12)18(11,17(23)24)21-28(25,26)15-8-7-14(27-15)22-10-13(19)9-20-22/h2-11,16,21H,1H3,(H,23,24)/t11-,16-,18+/m1/s1 GRSFKJZRDUZQPW-ONUMYQOESA-N 50311088 CHEMBL1078281::cis-rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2-sulfonamido)-2-methyl-3-phenylcyclopropanecarboxylic acid Disintegrin and metalloproteinase domain-containing protein 17 4000 ChEMBL 10.1016/j.bmcl.2009.08.093 10.7270/Q2ZS2WMT 19767207 Shiozaki, M; Imai, H; Maeda, K; Miura, T; Yasue, K; Suma, A; Yokota, M; Ogoshi, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311088&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46175170 104145449 CHEMBL1078281 ZINC48999878 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592527 COc1ccc2[nH]n(CC3(NC(=O)NC3=O)c3ccccc3)c(=O)c2c1 InChI=1S/C18H16N4O4/c1-26-12-7-8-14-13(9-12)15(23)22(21-14)10-18(11-5-3-2-4-6-11)16(24)19-17(25)20-18/h2-9,21H,10H2,1H3,(H2,19,20,24,25) OXEVTLWXFDHNQD-UHFFFAOYSA-N 50313824 5-((5-methoxy-3-oxo-1H-indazol-2(3H)-yl)methyl)-5-phenylimidazolidine-2,4-dione::CHEMBL1087293 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313824&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 727 3LE9 11566516 104148185 CHEMBL1087293 ZINC35825536 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592528 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(F)cc3)C(=O)c2c1 InChI=1S/C19H16FN3O4/c1-27-14-7-2-11-9-23(16(24)15(11)8-14)10-19(17(25)21-18(26)22-19)12-3-5-13(20)6-4-12/h2-8H,9-10H2,1H3,(H2,21,22,25,26)/t19-/m0/s1 YMUVKSFBWOSBKG-IBGZPJMESA-N 50313841 (R)-5-(4-fluorophenyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1089042 Disintegrin and metalloproteinase domain-containing protein 17 0.8 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50313841 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50313841&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46845559 104148202 CHEMBL1089042 ZINC49066938 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592529 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(Cl)cc3)C(=O)c2c1 InChI=1S/C25H20ClN3O4/c1-33-20-11-6-17-13-29(22(30)21(17)12-20)14-25(23(31)27-24(32)28-25)18-7-2-15(3-8-18)16-4-9-19(26)10-5-16/h2-12H,13-14H2,1H3,(H2,27,28,31,32)/t25-/m0/s1 VVDYUPNLOYAPRT-VWLOTQADSA-N 50324993 (R)-5-(4'-chlorobiphenyl-4-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1222723 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324993 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324993&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24890899 117646314 CHEMBL1222723 ZINC58591247 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592530 Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(F)cc3F)C(=O)c2c1 InChI=1S/C24H16F3N3O3/c25-16-6-3-14-11-30(21(31)19(14)9-16)12-24(22(32)28-23(33)29-24)15-4-1-13(2-5-15)18-8-7-17(26)10-20(18)27/h1-10H,11-12H2,(H2,28,29,32,33)/t24-/m0/s1 JPEBUILRDDQKEC-DEOSSOPVSA-N 50324994 (R)-5-(2',4'-difluorobiphenyl-4-yl)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1222801 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324994 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324994&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864990 117646315 CHEMBL1222801 ZINC35820821 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592531 Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(cc3)C(F)(F)F)C(=O)c2c1 InChI=1S/C25H17F4N3O3/c26-19-10-5-16-12-32(21(33)20(16)11-19)13-24(22(34)30-23(35)31-24)17-6-1-14(2-7-17)15-3-8-18(9-4-15)25(27,28)29/h1-11H,12-13H2,(H2,30,31,34,35)/t24-/m0/s1 QZJSMMIDRSHMNT-DEOSSOPVSA-N 50324995 (R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4'-(trifluoromethyl)biphenyl-4-yl)imidazolidine-2,4-dione::CHEMBL1222802 Disintegrin and metalloproteinase domain-containing protein 17 18 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324995 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324995&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864991 117646316 CHEMBL1222802 ZINC58591318 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592532 COC(=O)c1ccc(cc1)-c1ccc(cc1)[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O InChI=1S/C27H23N3O6/c1-35-21-12-9-19-14-30(23(31)22(19)13-21)15-27(25(33)28-26(34)29-27)20-10-7-17(8-11-20)16-3-5-18(6-4-16)24(32)36-2/h3-13H,14-15H2,1-2H3,(H2,28,29,33,34)/t27-/m0/s1 JRHJGDPOZXWYCA-MHZLTWQESA-N 50324996 (R)-methyl 4'-(4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)biphenyl-4-carboxylate::CHEMBL1222803 Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324996 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324996&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864992 117646317 CHEMBL1222803 ZINC58591319 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592533 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(cc3)C(N)=O)C(=O)c2c1 InChI=1S/C26H22N4O5/c1-35-20-11-8-18-13-30(23(32)21(18)12-20)14-26(24(33)28-25(34)29-26)19-9-6-16(7-10-19)15-2-4-17(5-3-15)22(27)31/h2-12H,13-14H2,1H3,(H2,27,31)(H2,28,29,33,34)/t26-/m0/s1 AXGTZSDDXHRQLL-SANMLTNESA-N 50324997 (R)-4'-(4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)biphenyl-4-carboxamide::CHEMBL1222804 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324997 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324997&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864993 117646318 CHEMBL1222804 ZINC58583993 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592534 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccccn3)C(=O)c2c1 InChI=1S/C24H20N4O4/c1-32-18-10-7-16-13-28(21(29)19(16)12-18)14-24(22(30)26-23(31)27-24)17-8-5-15(6-9-17)20-4-2-3-11-25-20/h2-12H,13-14H2,1H3,(H2,26,27,30,31)/t24-/m0/s1 JMIRNYQKOOQOBS-DEOSSOPVSA-N 50324998 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyridin-2-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222866 Disintegrin and metalloproteinase domain-containing protein 17 0.5 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324998 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324998&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865044 117646319 CHEMBL1222866 ZINC58590591 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592535 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cccnc3)C(=O)c2c1 InChI=1S/C24H20N4O4/c1-32-19-9-6-17-13-28(21(29)20(17)11-19)14-24(22(30)26-23(31)27-24)18-7-4-15(5-8-18)16-3-2-10-25-12-16/h2-12H,13-14H2,1H3,(H2,26,27,30,31)/t24-/m0/s1 XMSHNXONZBWQTA-DEOSSOPVSA-N 50324999 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyridin-3-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222867 Disintegrin and metalloproteinase domain-containing protein 17 0.77 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50324999 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50324999&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46934000 117646320 CHEMBL1222867 ZINC58468653 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592536 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccncc3)C(=O)c2c1 InChI=1S/C24H20N4O4/c1-32-19-7-4-17-13-28(21(29)20(17)12-19)14-24(22(30)26-23(31)27-24)18-5-2-15(3-6-18)16-8-10-25-11-9-16/h2-12H,13-14H2,1H3,(H2,26,27,30,31)/t24-/m0/s1 UNCBVXXZWZQBOV-DEOSSOPVSA-N 50325000 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyridin-4-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222868 Disintegrin and metalloproteinase domain-containing protein 17 0.6 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325000 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325000&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865045 117646321 CHEMBL1222868 ZINC58590510 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592537 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccnc(N)c3)C(=O)c2c1 InChI=1S/C24H21N5O4/c1-33-18-7-4-16-12-29(21(30)19(16)11-18)13-24(22(31)27-23(32)28-24)17-5-2-14(3-6-17)15-8-9-26-20(25)10-15/h2-11H,12-13H2,1H3,(H2,25,26)(H2,27,28,31,32)/t24-/m0/s1 BLBSVSQAGPCYLR-DEOSSOPVSA-N 50325001 (R)-5-(4-(2-aminopyridin-4-yl)phenyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1222869 Disintegrin and metalloproteinase domain-containing protein 17 1.4 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325001 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325001&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865046 117646322 CHEMBL1222869 ZINC58590512 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592538 Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(=O)[nH]c3)C(=O)c2c1 InChI=1S/C23H17FN4O4/c24-17-7-3-15-11-28(20(30)18(15)9-17)12-23(21(31)26-22(32)27-23)16-5-1-13(2-6-16)14-4-8-19(29)25-10-14/h1-10H,11-12H2,(H,25,29)(H2,26,27,31,32)/t23-/m0/s1 NLIDMRJVJJLMCT-QHCPKHFHSA-N 50325002 (R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4-(6-oxo-1,6-dihydropyridin-3-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222941 Disintegrin and metalloproteinase domain-containing protein 17 0.2 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325002 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325002&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46933693 117646323 CHEMBL1222941 ZINC58590594 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592539 Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3c[nH]c(=O)c(Cl)c3)C(=O)c2c1 InChI=1S/C23H16ClFN4O4/c24-18-7-14(9-26-19(18)30)12-1-4-15(5-2-12)23(21(32)27-22(33)28-23)11-29-10-13-3-6-16(25)8-17(13)20(29)31/h1-9H,10-11H2,(H,26,30)(H2,27,28,32,33)/t23-/m0/s1 HAVNLPXQZUUFQA-QHCPKHFHSA-N 50325003 (R)-5-(4-(5-chloro-6-oxo-1,6-dihydropyridin-3-yl)phenyl)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1222942 Disintegrin and metalloproteinase domain-containing protein 17 0.1 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325003 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325003&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46933999 117646324 CHEMBL1222942 ZINC34662589 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592540 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cncnc3)C(=O)c2c1 InChI=1S/C23H19N5O4/c1-32-18-7-4-15-11-28(20(29)19(15)8-18)12-23(21(30)26-22(31)27-23)17-5-2-14(3-6-17)16-9-24-13-25-10-16/h2-10,13H,11-12H2,1H3,(H2,26,27,30,31)/t23-/m0/s1 WYDYTZMGSQLLBJ-QHCPKHFHSA-N 50325004 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyrimidin-5-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222943 Disintegrin and metalloproteinase domain-containing protein 17 0.9 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325004 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325004&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865107 117646325 CHEMBL1222943 ZINC58655412 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592541 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3nccs3)C(=O)c2c1 InChI=1S/C22H18N4O4S/c1-30-16-7-4-14-11-26(19(27)17(14)10-16)12-22(20(28)24-21(29)25-22)15-5-2-13(3-6-15)18-23-8-9-31-18/h2-10H,11-12H2,1H3,(H2,24,25,28,29)/t22-/m0/s1 UIYHETGIGOJOLX-QFIPXVFZSA-N 50325005 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(thiazol-2-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222944 Disintegrin and metalloproteinase domain-containing protein 17 0.6 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325005 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325005&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865108 117646326 CHEMBL1222944 ZINC58582995 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592542 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cnccn3)C(=O)c2c1 InChI=1S/C23H19N5O4/c1-32-17-7-4-15-12-28(20(29)18(15)10-17)13-23(21(30)26-22(31)27-23)16-5-2-14(3-6-16)19-11-24-8-9-25-19/h2-11H,12-13H2,1H3,(H2,26,27,30,31)/t23-/m0/s1 MTFUHJWNZKKUJR-QHCPKHFHSA-N 50325006 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyrazin-2-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223004 Disintegrin and metalloproteinase domain-containing protein 17 1.2 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325006 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325006&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865165 117646327 CHEMBL1223004 ZINC58582862 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592543 Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cccnc3)C(=O)c2c1 InChI=1S/C23H17FN4O3/c24-18-8-5-16-12-28(20(29)19(16)10-18)13-23(21(30)26-22(31)27-23)17-6-3-14(4-7-17)15-2-1-9-25-11-15/h1-11H,12-13H2,(H2,26,27,30,31)/t23-/m0/s1 OWSBNVAFVUJPAH-QHCPKHFHSA-N 50325007 (R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyridin-3-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223005 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325007 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325007&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865166 117646328 CHEMBL1223005 ZINC35817838 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592544 Cc1noc(C)c1-c1ccc(cc1)[C@]1(CN2Cc3ccc(F)cc3C2=O)NC(=O)NC1=O InChI=1S/C23H19FN4O4/c1-12-19(13(2)32-27-12)14-3-6-16(7-4-14)23(21(30)25-22(31)26-23)11-28-10-15-5-8-17(24)9-18(15)20(28)29/h3-9H,10-11H2,1-2H3,(H2,25,26,30,31)/t23-/m0/s1 VGUBUIARGUEDGV-QHCPKHFHSA-N 50325008 (R)-5-(4-(3,5-dimethylisoxazol-4-yl)phenyl)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1223006 Disintegrin and metalloproteinase domain-containing protein 17 0.5 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325008&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865167 117646329 CHEMBL1223006 ZINC35970330 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592545 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cnn(C)c3)C(=O)c2c1 InChI=1S/C23H21N5O4/c1-27-11-16(10-24-27)14-3-6-17(7-4-14)23(21(30)25-22(31)26-23)13-28-12-15-5-8-18(32-2)9-19(15)20(28)29/h3-11H,12-13H2,1-2H3,(H2,25,26,30,31)/t23-/m0/s1 JHADKVOWWKZBNS-QHCPKHFHSA-N 50325009 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223007 Disintegrin and metalloproteinase domain-containing protein 17 0.88 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325009 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325009&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865168 117646330 CHEMBL1223007 ZINC58583204 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592546 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccnc(C)c3)C(=O)c2c1 InChI=1S/C25H22N4O4/c1-15-11-17(9-10-26-15)16-3-6-19(7-4-16)25(23(31)27-24(32)28-25)14-29-13-18-5-8-20(33-2)12-21(18)22(29)30/h3-12H,13-14H2,1-2H3,(H2,27,28,31,32)/t25-/m0/s1 HGPPYGXNQCWPLJ-VWLOTQADSA-N 50325010 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(2-methylpyridin-4-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223075 Disintegrin and metalloproteinase domain-containing protein 17 0.5 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325010 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325010&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46933694 117646331 CHEMBL1223075 ZINC58592435 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592547 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)C3(C)NC(=O)NC3=O)C(=O)c2c1 InChI=1S/C23H21N5O6/c1-22(18(30)24-20(32)26-22)13-4-6-14(7-5-13)23(19(31)25-21(33)27-23)11-28-10-12-3-8-15(34-2)9-16(12)17(28)29/h3-9H,10-11H2,1-2H3,(H2,24,26,30,32)(H2,25,27,31,33)/t22?,23-/m0/s1 VSLRQFPPNAAJGK-WCSIJFPASA-N 50325011 (5R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(4-methyl-2,5-dioxoimidazolidin-4-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223076 Disintegrin and metalloproteinase domain-containing protein 17 2.6 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325011 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325011&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865223 117646332 CHEMBL1223076 ZINC62224953 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592548 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc4cn(C)nc4c3)C(=O)c2c1 InChI=1S/C27H23N5O4/c1-31-13-19-4-3-17(11-23(19)30-31)16-5-8-20(9-6-16)27(25(34)28-26(35)29-27)15-32-14-18-7-10-21(36-2)12-22(18)24(32)33/h3-13H,14-15H2,1-2H3,(H2,28,29,34,35)/t27-/m0/s1 ILWKYNOKRNHWCN-MHZLTWQESA-N 50325012 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(2-methyl-2H-indazol-6-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223077 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325012 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325012&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865224 117646333 CHEMBL1223077 ZINC58583238 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592549 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cnc4n(C)ccc4c3)C(=O)c2c1 InChI=1S/C27H23N5O4/c1-31-10-9-17-11-19(13-28-23(17)31)16-3-6-20(7-4-16)27(25(34)29-26(35)30-27)15-32-14-18-5-8-21(36-2)12-22(18)24(32)33/h3-13H,14-15H2,1-2H3,(H2,29,30,34,35)/t27-/m0/s1 PAQYCNQIRSCTLV-MHZLTWQESA-N 50325013 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(1-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223078 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325013 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325013&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865225 117646334 CHEMBL1223078 ZINC58583539 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592550 Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc4ncccc4c3)C(=O)c2c1 InChI=1S/C27H19FN4O3/c28-21-9-5-19-14-32(24(33)22(19)13-21)15-27(25(34)30-26(35)31-27)20-7-3-16(4-8-20)17-6-10-23-18(12-17)2-1-11-29-23/h1-13H,14-15H2,(H2,30,31,34,35)/t27-/m0/s1 MSAVYVGBRRGZOA-MHZLTWQESA-N 50325014 (R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4-(quinolin-6-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223153 Disintegrin and metalloproteinase domain-containing protein 17 0.8 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325014 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325014&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865286 117646335 CHEMBL1223153 ZINC58582660 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592551 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3ccc(cc3)-c3cc[nH]n3)C(=O)c2c1 InChI=1S/C28H23N5O4/c1-37-22-11-8-20-15-33(25(34)23(20)14-22)16-28(26(35)30-27(36)31-28)21-9-6-18(7-10-21)17-2-4-19(5-3-17)24-12-13-29-32-24/h2-14H,15-16H2,1H3,(H,29,32)(H2,30,31,35,36)/t28-/m0/s1 SMFXJQFOJPRACG-NDEPHWFRSA-N 50325015 (R)-5-(4'-(1H-pyrazol-3-yl)biphenyl-4-yl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1223154 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325015 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325015&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865287 117646336 CHEMBL1223154 ZINC58583135 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592552 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cccc(c3)-c3csc(C)n3)C(=O)c2c1 InChI=1S/C29H24N4O4S/c1-17-30-25(15-38-17)20-5-3-4-19(12-20)18-6-9-22(10-7-18)29(27(35)31-28(36)32-29)16-33-14-21-8-11-23(37-2)13-24(21)26(33)34/h3-13,15H,14,16H2,1-2H3,(H2,31,32,35,36)/t29-/m0/s1 SSTRFTZNDZPMLC-LJAQVGFWSA-N 50325016 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(3'-(2-methylthiazol-4-yl)biphenyl-4-yl)imidazolidine-2,4-dione::CHEMBL1223155 Disintegrin and metalloproteinase domain-containing protein 17 31 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325016 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325016&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865288 117646337 CHEMBL1223155 ZINC58583137 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592553 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)-c3cc(no3)-c3ccccc3)C(=O)c2c1 InChI=1S/C28H22N4O5/c1-36-21-12-9-19-15-32(25(33)22(19)13-21)16-28(26(34)29-27(35)30-28)20-10-7-18(8-11-20)24-14-23(31-37-24)17-5-3-2-4-6-17/h2-14H,15-16H2,1H3,(H2,29,30,34,35)/t28-/m0/s1 NVWXOYMJYWFJGW-NDEPHWFRSA-N 50325017 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(3-phenylisoxazol-5-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1223223 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325017&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865338 117646338 CHEMBL1223223 ZINC58590673 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592554 Cn1nnnc1-c1ccccc1-c1ccc(cc1)[C@]1(CN2Cc3ccc(F)cc3C2=O)NC(=O)NC1=O InChI=1S/C26H20FN7O3/c1-33-22(30-31-32-33)20-5-3-2-4-19(20)15-6-9-17(10-7-15)26(24(36)28-25(37)29-26)14-34-13-16-8-11-18(27)12-21(16)23(34)35/h2-12H,13-14H2,1H3,(H2,28,29,36,37)/t26-/m0/s1 AQOFRQLPFVJDJX-SANMLTNESA-N 50325018 (5R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(2'-(1-methyl-1H-tetrazol-5-yl)biphenyl-4-yl)imidazolidine-2,4-dione::CHEMBL1223224 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325018&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49865339 117646339 CHEMBL1223224 ZINC58590945 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592555 Fc1ccc2CN(CC3(NC(=O)NC3=O)c3ccccc3Oc3ccccc3)C(=O)c2c1 InChI=1S/C24H18FN3O4/c25-16-11-10-15-13-28(21(29)18(15)12-16)14-24(22(30)26-23(31)27-24)19-8-4-5-9-20(19)32-17-6-2-1-3-7-17/h1-12H,13-14H2,(H2,26,27,30,31) BZUYBPJHIORQOF-UHFFFAOYSA-N 50325019 (+/-)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(2-phenoxyphenyl)imidazolidine-2,4-dione::CHEMBL1222721 Disintegrin and metalloproteinase domain-containing protein 17 29 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325019 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325019&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864940 117646340 CHEMBL1222721 ZINC62224955 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592556 Fc1ccc2CN(CC3(NC(=O)NC3=O)c3cccc(Oc4ccccc4)c3)C(=O)c2c1 InChI=1S/C24H18FN3O4/c25-17-10-9-15-13-28(21(29)20(15)12-17)14-24(22(30)26-23(31)27-24)16-5-4-8-19(11-16)32-18-6-2-1-3-7-18/h1-12H,13-14H2,(H2,26,27,30,31) ZQEAQUSWNZXSRY-UHFFFAOYSA-N 50325020 (+/-)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(3-phenoxyphenyl)imidazolidine-2,4-dione::CHEMBL1222722 Disintegrin and metalloproteinase domain-containing protein 17 27 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325020 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325020&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864941 117646341 CHEMBL1222722 ZINC62224959 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592557 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(OC4CCCC4)cc3)C(=O)c2c1 InChI=1S/C24H25N3O5/c1-31-19-9-6-15-13-27(21(28)20(15)12-19)14-24(22(29)25-23(30)26-24)16-7-10-18(11-8-16)32-17-4-2-3-5-17/h6-12,17H,2-5,13-14H2,1H3,(H2,25,26,29,30)/t24-/m0/s1 NIDIGSMSQOBKBC-DEOSSOPVSA-N 50325021 (R)-5-(4-(cyclopentyloxy)phenyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1222588 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864868 117646342 CHEMBL1222588 ZINC58583463 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592558 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(Oc4ccncc4)cc3)C(=O)c2c1 InChI=1S/C24H20N4O5/c1-32-19-5-2-15-13-28(21(29)20(15)12-19)14-24(22(30)26-23(31)27-24)16-3-6-17(7-4-16)33-18-8-10-25-11-9-18/h2-12H,13-14H2,1H3,(H2,26,27,30,31)/t24-/m0/s1 LBNRJKNNQUPQBH-DEOSSOPVSA-N 50325022 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyridin-4-yloxy)phenyl)imidazolidine-2,4-dione::CHEMBL1222652 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325022&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864904 117646343 CHEMBL1222652 ZINC58592423 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592559 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(Oc4ccc5cnccc5c4)cc3)C(=O)c2c1 InChI=1S/C28H22N4O5/c1-36-22-6-3-19-15-32(25(33)24(19)13-22)16-28(26(34)30-27(35)31-28)20-4-8-21(9-5-20)37-23-7-2-18-14-29-11-10-17(18)12-23/h2-14H,15-16H2,1H3,(H2,30,31,34,35)/t28-/m0/s1 OYHZLHWZRAXZTL-NDEPHWFRSA-N 50325023 (R)-5-(4-(isoquinolin-6-yloxy)phenyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1222653 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325023 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325023&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864905 117646344 CHEMBL1222653 ZINC58582647 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592560 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)N3CCOCC3)C(=O)c2c1 InChI=1S/C23H24N4O5/c1-31-18-7-2-15-13-27(20(28)19(15)12-18)14-23(21(29)24-22(30)25-23)16-3-5-17(6-4-16)26-8-10-32-11-9-26/h2-7,12H,8-11,13-14H2,1H3,(H2,24,25,29,30)/t23-/m0/s1 BTJKVNPETLTKDC-QHCPKHFHSA-N 50325024 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-morpholinophenyl)imidazolidine-2,4-dione::CHEMBL1222654 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325024&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864906 117646345 CHEMBL1222654 ZINC58584031 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592561 Fc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)N3CCCC3=O)C(=O)c2c1 InChI=1S/C22H19FN4O4/c23-15-6-3-13-11-26(19(29)17(13)10-15)12-22(20(30)24-21(31)25-22)14-4-7-16(8-5-14)27-9-1-2-18(27)28/h3-8,10H,1-2,9,11-12H2,(H2,24,25,30,31)/t22-/m0/s1 ZYKDRBDNKSNCHT-QFIPXVFZSA-N 50325025 (R)-5-((6-fluoro-1-oxoisoindolin-2-yl)methyl)-5-(4-(2-oxopyrrolidin-1-yl)phenyl)imidazolidine-2,4-dione::CHEMBL1222655 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325025&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11546305 117646346 CHEMBL1222655 ZINC34661543 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50592562 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)c3ccc(cc3)C(=O)N3CCCC3)C(=O)c2c1 InChI=1S/C24H24N4O5/c1-33-18-9-6-16-13-28(21(30)19(16)12-18)14-24(22(31)25-23(32)26-24)17-7-4-15(5-8-17)20(29)27-10-2-3-11-27/h4-9,12H,2-3,10-11,13-14H2,1H3,(H2,25,26,31,32)/t24-/m0/s1 RSQXOJGRSJDUMV-DEOSSOPVSA-N 50325026 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(4-(pyrrolidine-1-carbonyl)phenyl)imidazolidine-2,4-dione::CHEMBL1222720 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2010.06.134 10.7270/Q26W9B8K 20663669 Yu, W; Tong, L; Kim, SH; Wong, MK; Chen, L; Yang, DY; Shankar, BB; Lavey, BJ; Zhou, G; Kosinski, A; Rizvi, R; Li, D; Feltz, RJ; Piwinski, JJ; Rosner, KE; Shih, NY; Siddiqui, MA; Guo, Z; Orth, P; Shah, H; Sun, J; Umland, S; Lundell, DJ; Niu, X; Kozlowski, JA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50325026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50325026&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 49864939 117646347 CHEMBL1222720 ZINC58592861 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015629 COc1cc(Oc2ccc(cc2)S(=O)(=O)CC(C)C(=O)NO)cc(OC)c1OC InChI=1S/C19H23NO8S/c1-12(19(21)20-22)11-29(23,24)15-7-5-13(6-8-15)28-14-9-16(25-2)18(27-4)17(10-14)26-3/h5-10,12,22H,11H2,1-4H3,(H,20,21) LUOBAMXDTNOZAD-UHFFFAOYSA-N 50106017 CHEMBL421009::N-Hydroxy-2-methyl-3-[4-(3,4,5-trimethoxy-phenoxy)-benzenesulfonyl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 6.5 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106017 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106017&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910282 104001597 CHEMBL421009 ZINC26739689 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015630 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3cc(C)cc(c3)C(C)C)C(=O)N1)C(=O)NO)cc2 InChI=1S/C31H43N3O5/c1-20(2)24-17-21(3)16-23(18-24)8-7-10-26-27(30(36)34-38)9-5-6-15-39-25-13-11-22(12-14-25)19-28(31(37)32-4)33-29(26)35/h11-14,16-18,20,26-28,38H,5-10,15,19H2,1-4H3,(H,32,37)(H,33,35)(H,34,36)/t26-,27+,28+/m1/s1 YINOLIYDTHQXKP-PKTNWEFCSA-N 50106021 (7S,8R,11S)-8-[3-(3-isopropyl-5-methyl-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL99283 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44329943 104001601 CHEMBL99283 ZINC26732261 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625243 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2ccc(F)cc2C(F)(F)F)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C25H31F5N4O4S/c1-17(23-31-13-21(27)14-32-23)12-24(2,34(36)16-35)15-39(37,38)33-9-7-18(8-10-33)3-4-19-5-6-20(26)11-22(19)25(28,29)30/h5-6,11,13-14,16-18,36H,3-4,7-10,12,15H2,1-2H3/t17-,24-/m0/s1 JGAIDLBSMBNOAG-XDHUDOTRSA-N 50337731 CHEMBL1683453::N-((2S,4S)-1-(4-(4-fluoro-2-(trifluoromethyl)phenethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8e Disintegrin and metalloproteinase domain-containing protein 17 19 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337731 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337731&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53321542 125087833 CHEMBL1683453 ZINC66079903 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625245 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2ccc(F)cc2C)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C25H34F2N4O4S/c1-18-12-22(26)7-6-21(18)5-4-20-8-10-30(11-9-20)36(34,35)16-25(3,31(33)17-32)13-19(2)24-28-14-23(27)15-29-24/h6-7,12,14-15,17,19-20,33H,4-5,8-11,13,16H2,1-3H3/t19-,25-/m0/s1 IXKRFERDVUXQLW-DFBJGRDBSA-N 50337721 CHEMBL1683454::N-((2S,4S)-1-(4-(4-fluoro-2-methylphenethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8g Disintegrin and metalloproteinase domain-containing protein 17 21 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337721 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337721&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53318911 125087823 CHEMBL1683454 ZINC66079906 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625246 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2cc(C)ccc2C)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C26H37FN4O4S/c1-19-5-6-20(2)23(13-19)8-7-22-9-11-30(12-10-22)36(34,35)17-26(4,31(33)18-32)14-21(3)25-28-15-24(27)16-29-25/h5-6,13,15-16,18,21-22,33H,7-12,14,17H2,1-4H3/t21-,26-/m0/s1 NYJKRUFCTNREQN-LVXARBLLSA-N 50337727 CHEMBL1683457::N-((2S,4S)-1-(4-(2,5-dimethylphenethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8j Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337727 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337727&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53318912 125087829 CHEMBL1683457 ZINC66074978 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625255 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2cc(C)ncc2C)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C25H36FN5O4S/c1-18(24-28-14-23(26)15-29-24)12-25(4,31(33)17-32)16-36(34,35)30-9-7-21(8-10-30)5-6-22-11-20(3)27-13-19(22)2/h11,13-15,17-18,21,33H,5-10,12,16H2,1-4H3/t18-,25-/m0/s1 SOTNGZPOQMJOPI-BVZFJXPGSA-N 50337724 CHEMBL1683458::N-((2S,4S)-1-(4-(2-(2,5-dimethylpyridin-4-yl)ethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8k Disintegrin and metalloproteinase domain-containing protein 17 230 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337724 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337724&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53325499 125087826 CHEMBL1683458 ZINC66074979 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625256 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2c(C)noc2C)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C23H34FN5O5S/c1-16(22-25-12-20(24)13-26-22)11-23(4,29(31)15-30)14-35(32,33)28-9-7-19(8-10-28)5-6-21-17(2)27-34-18(21)3/h12-13,15-16,19,31H,5-11,14H2,1-4H3/t16-,23-/m0/s1 UAGAABCJKYADIR-HJPURHCSSA-N 50337735 CHEMBL1615187::N-[(2S,4S)-1-({4-[2-(3,5-dimethyl-1,2-oxazol-4-yl)ethyl]piperidin-1-yl}sulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl]-N-hydroxyformamide::US10322143, Compound 8m Disintegrin and metalloproteinase domain-containing protein 17 250 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337735 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337735&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search QHF 3Q2H 50990921 125087837 CHEMBL1615187 ZINC64744200 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625263 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2ccc(cc2C)C(F)(F)F)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C26H34F4N4O4S/c1-18-12-22(26(28,29)30)7-6-21(18)5-4-20-8-10-33(11-9-20)39(37,38)16-25(3,34(36)17-35)13-19(2)24-31-14-23(27)15-32-24/h6-7,12,14-15,17,19-20,36H,4-5,8-11,13,16H2,1-3H3/t19-,25-/m0/s1 AYZCFZMCYDMFMY-DFBJGRDBSA-N 50337736 CHEMBL1683455::N-((2S,4S)-4-(5-fluoropyrimidin-2-yl)-2-methyl-1-(4-(2-methyl-4-(trifluoromethyl)phenethyl)piperidin-1-ylsulfonyl)pentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8h Disintegrin and metalloproteinase domain-containing protein 17 420 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337736 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337736&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53320225 125087838 CHEMBL1683455 ZINC66098546 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625272 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2cc(C)cnc2C)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C25H36FN5O4S/c1-18-11-22(20(3)27-13-18)6-5-21-7-9-30(10-8-21)36(34,35)16-25(4,31(33)17-32)12-19(2)24-28-14-23(26)15-29-24/h11,13-15,17,19,21,33H,5-10,12,16H2,1-4H3/t19-,25-/m0/s1 PQEGPXRQOCZFEH-DFBJGRDBSA-N 50337737 CHEMBL1683459::N-((2S,4S)-1-(4-(2-(2,5-dimethylpyridin-3-yl)ethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8l Disintegrin and metalloproteinase domain-containing protein 17 1400 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337737&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53322877 125087839 CHEMBL1683459 ZINC66080165 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625283 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2cc(C)nn2C)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C23H35FN6O4S/c1-17(22-25-13-20(24)14-26-22)12-23(3,30(32)16-31)15-35(33,34)29-9-7-19(8-10-29)5-6-21-11-18(2)27-28(21)4/h11,13-14,16-17,19,32H,5-10,12,15H2,1-4H3/t17-,23-/m0/s1 PDHFGTGPEOIGCF-SBUREZEXSA-N 50337742 CHEMBL1683465::N-((2S,4S)-1-(4-(2-(1,3-dimethyl-1H-pyrazol-5-yl)ethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8r Disintegrin and metalloproteinase domain-containing protein 17 2800 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337742&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53324260 125087844 CHEMBL1683465 ZINC66078967 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625284 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2cnc(C)cc2C)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C25H36FN5O4S/c1-18-11-20(3)27-13-22(18)6-5-21-7-9-30(10-8-21)36(34,35)16-25(4,31(33)17-32)12-19(2)24-28-14-23(26)15-29-24/h11,13-15,17,19,21,33H,5-10,12,16H2,1-4H3/t19-,25-/m0/s1 ICCQWMPCYVXIPA-DFBJGRDBSA-N 50337739 CHEMBL1683461::N-((2S,4S)-1-(4-(2-(4,6-dimethylpyridin-3-yl)ethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8n Disintegrin and metalloproteinase domain-containing protein 17 3000 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337739 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337739&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53322879 125087841 CHEMBL1683461 ZINC66077842 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625285 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2ccc(cc2C2CC2)C(F)(F)F)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C28H36F4N4O4S/c1-19(26-33-15-24(29)16-34-26)14-27(2,36(38)18-37)17-41(39,40)35-11-9-20(10-12-35)3-4-21-7-8-23(28(30,31)32)13-25(21)22-5-6-22/h7-8,13,15-16,18-20,22,38H,3-6,9-12,14,17H2,1-2H3/t19-,27-/m0/s1 HUWMGZNULSXXSW-PPHZAIPVSA-N 50337743 CHEMBL1683456::N-((2S,4S)-1-(4-(2-cyclopropyl-4-(trifluoromethyl)phenethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8i Disintegrin and metalloproteinase domain-containing protein 17 3200 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337743 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337743&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53325498 125087845 CHEMBL1683456 ZINC66074977 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625291 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2ccc(cc2Cl)S(C)(=O)=O)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C25H34ClFN4O6S2/c1-18(24-28-14-21(27)15-29-24)13-25(2,31(33)17-32)16-39(36,37)30-10-8-19(9-11-30)4-5-20-6-7-22(12-23(20)26)38(3,34)35/h6-7,12,14-15,17-19,33H,4-5,8-11,13,16H2,1-3H3/t18-,25-/m0/s1 BWHNAQMOABQLDB-BVZFJXPGSA-N 50337734 CHEMBL1683464::N-((2S,4S)-1-(4-(2-chloro-4-(methylsulfonyl)phenethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8q Disintegrin and metalloproteinase domain-containing protein 17 5500 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337734 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337734&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53320227 125087836 CHEMBL1683464 ZINC66078486 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611964 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccccc3)C(=O)c2c1 InChI=1S/C21H17N3O4/c1-28-16-8-7-15-12-24(18(25)17(15)11-16)13-21(19(26)22-20(27)23-21)10-9-14-5-3-2-4-6-14/h2-8,11H,12-13H2,1H3,(H2,22,23,26,27)/t21-/m1/s1 LBDNRBQSFVHTLL-OAQYLSRUSA-N 50332262 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(phenylethynyl)imidazolidine-2,4-dione::CHEMBL1287998 Disintegrin and metalloproteinase domain-containing protein 17 0.140000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332262 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332262&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52948549 123111377 CHEMBL1287998 ZINC64559315 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611965 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(F)cc3)C(=O)c2c1 InChI=1S/C21H16FN3O4/c1-29-16-7-4-14-11-25(18(26)17(14)10-16)12-21(19(27)23-20(28)24-21)9-8-13-2-5-15(22)6-3-13/h2-7,10H,11-12H2,1H3,(H2,23,24,27,28)/t21-/m1/s1 AOGLMYLOFXJKAD-OAQYLSRUSA-N 50332263 (R)-5-((4-fluorophenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288028 Disintegrin and metalloproteinase domain-containing protein 17 0.260000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332263 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332263&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17754304 123111378 CHEMBL1288028 ZINC64549270 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611966 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccc(F)c3)C(=O)c2c1 InChI=1S/C21H16FN3O4/c1-29-16-6-5-14-11-25(18(26)17(14)10-16)12-21(19(27)23-20(28)24-21)8-7-13-3-2-4-15(22)9-13/h2-6,9-10H,11-12H2,1H3,(H2,23,24,27,28)/t21-/m1/s1 GMRHTWNZRNDTLI-OAQYLSRUSA-N 50332264 (R)-5-((3-fluorophenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288029 Disintegrin and metalloproteinase domain-containing protein 17 0.200000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332264 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332264&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17754779 123111379 CHEMBL1288029 ZINC64549271 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611967 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccccc3F)C(=O)c2c1 InChI=1S/C21H16FN3O4/c1-29-15-7-6-14-11-25(18(26)16(14)10-15)12-21(19(27)23-20(28)24-21)9-8-13-4-2-3-5-17(13)22/h2-7,10H,11-12H2,1H3,(H2,23,24,27,28)/t21-/m1/s1 LZAWUKXXZFCEMY-OAQYLSRUSA-N 50332265 (R)-5-((2-fluorophenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288059 Disintegrin and metalloproteinase domain-containing protein 17 0.130000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332265 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332265&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52942483 123111380 CHEMBL1288059 ZINC64559457 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611968 COc1ccc(cc1)C#C[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O InChI=1S/C22H19N3O5/c1-29-16-6-3-14(4-7-16)9-10-22(20(27)23-21(28)24-22)13-25-12-15-5-8-17(30-2)11-18(15)19(25)26/h3-8,11H,12-13H2,1-2H3,(H2,23,24,27,28)/t22-/m1/s1 VRGMRKNAXIYVGL-JOCHJYFZSA-N 50332266 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-((4-methoxyphenyl)ethynyl)imidazolidine-2,4-dione::CHEMBL1288060 Disintegrin and metalloproteinase domain-containing protein 17 0.410000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332266 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332266&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52947338 123111381 CHEMBL1288060 ZINC64559458 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611969 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccc(c3)C(C)C)C(=O)c2c1 InChI=1S/C24H23N3O4/c1-15(2)17-6-4-5-16(11-17)9-10-24(22(29)25-23(30)26-24)14-27-13-18-7-8-19(31-3)12-20(18)21(27)28/h4-8,11-12,15H,13-14H2,1-3H3,(H2,25,26,29,30)/t24-/m1/s1 LFJWTKGLUHCQQL-XMMPIXPASA-N 50332267 (R)-5-((3-isopropylphenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288090 Disintegrin and metalloproteinase domain-containing protein 17 0.500000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332267 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332267&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52941256 123111382 CHEMBL1288090 ZINC64560309 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611970 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccc(C)c3)C(=O)c2c1 InChI=1S/C22H19N3O4/c1-14-4-3-5-15(10-14)8-9-22(20(27)23-21(28)24-22)13-25-12-16-6-7-17(29-2)11-18(16)19(25)26/h3-7,10-11H,12-13H2,1-2H3,(H2,23,24,27,28)/t22-/m1/s1 LUWQGOYLKPARQB-JOCHJYFZSA-N 50332268 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(m-tolylethynyl)imidazolidine-2,4-dione::CHEMBL1288091 Disintegrin and metalloproteinase domain-containing protein 17 0.720000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332268 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332268&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52949779 123111383 CHEMBL1288091 ZINC64560311 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611971 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccccc3C)C(=O)c2c1 InChI=1S/C22H19N3O4/c1-14-5-3-4-6-15(14)9-10-22(20(27)23-21(28)24-22)13-25-12-16-7-8-17(29-2)11-18(16)19(25)26/h3-8,11H,12-13H2,1-2H3,(H2,23,24,27,28)/t22-/m1/s1 QCVXMNJEVPBACX-JOCHJYFZSA-N 50332269 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(o-tolylethynyl)imidazolidine-2,4-dione::CHEMBL1288121 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332269 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332269&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52946125 123111384 CHEMBL1288121 ZINC64560580 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611972 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccc(c3)C#N)C(=O)c2c1 InChI=1S/C22H16N4O4/c1-30-17-6-5-16-12-26(19(27)18(16)10-17)13-22(20(28)24-21(29)25-22)8-7-14-3-2-4-15(9-14)11-23/h2-6,9-10H,12-13H2,1H3,(H2,24,25,28,29)/t22-/m1/s1 WVQWBJZMWQUZLL-JOCHJYFZSA-N 50332270 (R)-3-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)ethynyl)benzonitrile::CHEMBL1288122 Disintegrin and metalloproteinase domain-containing protein 17 0.060000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332270 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332270&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17754781 123111385 CHEMBL1288122 ZINC64560581 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611973 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccc(c3)C(N)=O)C(=O)c2c1 InChI=1S/C22H18N4O5/c1-31-16-6-5-15-11-26(19(28)17(15)10-16)12-22(20(29)24-21(30)25-22)8-7-13-3-2-4-14(9-13)18(23)27/h2-6,9-10H,11-12H2,1H3,(H2,23,27)(H2,24,25,29,30)/t22-/m1/s1 WVNBFDNHAXDOOB-JOCHJYFZSA-N 50332271 (R)-3-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)ethynyl)benzamide::CHEMBL1288151 Disintegrin and metalloproteinase domain-containing protein 17 0.850000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332271 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332271&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52947372 123111386 CHEMBL1288151 ZINC64560773 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611974 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)C(N)=O)C(=O)c2c1 InChI=1S/C22H18N4O5/c1-31-16-7-6-15-11-26(19(28)17(15)10-16)12-22(20(29)24-21(30)25-22)9-8-13-2-4-14(5-3-13)18(23)27/h2-7,10H,11-12H2,1H3,(H2,23,27)(H2,24,25,29,30)/t22-/m1/s1 KSSYTEDVQNYYGE-JOCHJYFZSA-N 50332272 (R)-4-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)ethynyl)benzamide::CHEMBL1288152 Disintegrin and metalloproteinase domain-containing protein 17 0.560000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332272 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332272&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52942509 123111387 CHEMBL1288152 ZINC64573147 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611975 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccccc3C(N)=O)C(=O)c2c1 InChI=1S/C22H18N4O5/c1-31-15-7-6-14-11-26(19(28)17(14)10-15)12-22(20(29)24-21(30)25-22)9-8-13-4-2-3-5-16(13)18(23)27/h2-7,10H,11-12H2,1H3,(H2,23,27)(H2,24,25,29,30)/t22-/m1/s1 NWWNIDJIHDZVFT-JOCHJYFZSA-N 50332273 (R)-2-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)ethynyl)benzamide::CHEMBL1288182 Disintegrin and metalloproteinase domain-containing protein 17 2.8 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332273 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332273&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52941292 123111388 CHEMBL1288182 ZINC64573641 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611976 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)C(=O)NC3CC3)C(=O)c2c1 InChI=1S/C25H22N4O5/c1-34-19-9-6-17-13-29(22(31)20(17)12-19)14-25(23(32)27-24(33)28-25)11-10-15-2-4-16(5-3-15)21(30)26-18-7-8-18/h2-6,9,12,18H,7-8,13-14H2,1H3,(H,26,30)(H2,27,28,32,33)/t25-/m1/s1 XMKMZXIRNBFMBB-RUZDIDTESA-N 50332274 (R)-N-cyclopropyl-4-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)ethynyl)benzamide::CHEMBL1288183 Disintegrin and metalloproteinase domain-containing protein 17 2.6 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332274 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332274&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52943705 123111389 CHEMBL1288183 ZINC64573643 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611977 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(CC(N)=O)cc3)C(=O)c2c1 InChI=1S/C23H20N4O5/c1-32-17-7-6-16-12-27(20(29)18(16)11-17)13-23(21(30)25-22(31)26-23)9-8-14-2-4-15(5-3-14)10-19(24)28/h2-7,11H,10,12-13H2,1H3,(H2,24,28)(H2,25,26,30,31)/t23-/m1/s1 CIMXKGKYBNXAKQ-HSZRJFAPSA-N 102890 CHEMBL1288211::US8541572, 2283 Disintegrin and metalloproteinase domain-containing protein 17 0.420000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102890 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102890&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52949816 172098181 CHEMBL1288211 ZINC96173806 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611978 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)C(C)=O)C(=O)c2c1 InChI=1S/C23H19N3O5/c1-14(27)16-5-3-15(4-6-16)9-10-23(21(29)24-22(30)25-23)13-26-12-17-7-8-18(31-2)11-19(17)20(26)28/h3-8,11H,12-13H2,1-2H3,(H2,24,25,29,30)/t23-/m1/s1 WJCXDUFRUQUBIL-HSZRJFAPSA-N 50332276 (R)-5-((4-acetylphenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288212 Disintegrin and metalloproteinase domain-containing protein 17 0.500000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332276 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332276&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52944923 123111391 CHEMBL1288212 ZINC64560749 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611979 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)[C@H](C)N)C(=O)c2c1 InChI=1S/C23H22N4O4/c1-14(24)16-5-3-15(4-6-16)9-10-23(21(29)25-22(30)26-23)13-27-12-17-7-8-18(31-2)11-19(17)20(27)28/h3-8,11,14H,12-13,24H2,1-2H3,(H2,25,26,29,30)/t14-,23+/m0/s1 JLSSUXZVBDSGFX-LFVRLGFBSA-N 50332277 (R)-5-((4-((S)-1-aminoethyl)phenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288240 Disintegrin and metalloproteinase domain-containing protein 17 2.4 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332277 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332277&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52950115 123111392 CHEMBL1288240 ZINC64573041 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611980 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc4[nH]ccc4c3)C(=O)c2c1 InChI=1S/C23H18N4O4/c1-31-17-4-3-16-12-27(20(28)18(16)11-17)13-23(21(29)25-22(30)26-23)8-6-14-2-5-19-15(10-14)7-9-24-19/h2-5,7,9-11,24H,12-13H2,1H3,(H2,25,26,29,30)/t23-/m1/s1 JVSTYSFDPAVLLJ-HSZRJFAPSA-N 50332278 (R)-5-((1H-indol-5-yl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288241 Disintegrin and metalloproteinase domain-containing protein 17 0.170000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332278 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332278&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52941303 123111393 CHEMBL1288241 ZINC64573408 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611981 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc4cc[nH]c4c3)C(=O)c2c1 InChI=1S/C23H18N4O4/c1-31-17-5-4-16-12-27(20(28)18(16)11-17)13-23(21(29)25-22(30)26-23)8-6-14-2-3-15-7-9-24-19(15)10-14/h2-5,7,9-11,24H,12-13H2,1H3,(H2,25,26,29,30)/t23-/m1/s1 QBBIIQFBUDNRQD-HSZRJFAPSA-N 50332279 (R)-5-((1H-indol-6-yl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288267 Disintegrin and metalloproteinase domain-containing protein 17 0.190000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332279 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332279&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52942531 123111394 CHEMBL1288267 ZINC64559039 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611982 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc4cnn(C)c4c3)C(=O)c2c1 InChI=1S/C23H19N5O4/c1-27-19-9-14(3-4-15(19)11-24-27)7-8-23(21(30)25-22(31)26-23)13-28-12-16-5-6-17(32-2)10-18(16)20(28)29/h3-6,9-11H,12-13H2,1-2H3,(H2,25,26,30,31)/t23-/m1/s1 XMCBWYSBKLBUDX-HSZRJFAPSA-N 50332280 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-((1-methyl-1H-indazol-6-yl)ethynyl)imidazolidine-2,4-dione::CHEMBL1288268 Disintegrin and metalloproteinase domain-containing protein 17 0.520000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332280 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332280&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17754605 123111395 CHEMBL1288268 ZINC64559040 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611983 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc4nc[nH]c4c3)C(=O)c2c1 InChI=1S/C22H17N5O4/c1-31-15-4-3-14-10-27(19(28)16(14)9-15)11-22(20(29)25-21(30)26-22)7-6-13-2-5-17-18(8-13)24-12-23-17/h2-5,8-9,12H,10-11H2,1H3,(H,23,24)(H2,25,26,29,30)/t22-/m1/s1 RYWQUAWGPJFTEM-JOCHJYFZSA-N 50332281 (R)-5-((1H-benzo[d]imidazol-5-yl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288295 Disintegrin and metalloproteinase domain-containing protein 17 0.600000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332281 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332281&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52947420 123111396 CHEMBL1288295 ZINC64549047 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611984 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc4[nH]c(=O)[nH]c4c3)C(=O)c2c1 InChI=1S/C22H17N5O5/c1-32-14-4-3-13-10-27(18(28)15(13)9-14)11-22(19(29)25-21(31)26-22)7-6-12-2-5-16-17(8-12)24-20(30)23-16/h2-5,8-9H,10-11H2,1H3,(H2,23,24,30)(H2,25,26,29,31)/t22-/m1/s1 HIGAESVQLVHANA-JOCHJYFZSA-N 50332282 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)ethynyl)imidazolidine-2,4-dione::CHEMBL1288296 Disintegrin and metalloproteinase domain-containing protein 17 0.530000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332282 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332282&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52945321 123111397 CHEMBL1288296 ZINC64549442 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611985 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cccnc3)C(=O)c2c1 InChI=1S/C20H16N4O4/c1-28-15-5-4-14-11-24(17(25)16(14)9-15)12-20(18(26)22-19(27)23-20)7-6-13-3-2-8-21-10-13/h2-5,8-10H,11-12H2,1H3,(H2,22,23,26,27)/t20-/m1/s1 FYZPCUXRTDXRBF-HXUWFJFHSA-N 50332283 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-(pyridin-3-ylethynyl)imidazolidine-2,4-dione::CHEMBL1287851 Disintegrin and metalloproteinase domain-containing protein 17 0.620000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332283 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332283&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17754305 123111398 CHEMBL1287851 ZINC64559287 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611986 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3cnc4nc[nH]c4c3)C(=O)c2c1 InChI=1S/C21H16N6O4/c1-31-14-3-2-13-9-27(18(28)15(13)7-14)10-21(19(29)25-20(30)26-21)5-4-12-6-16-17(22-8-12)24-11-23-16/h2-3,6-8,11H,9-10H2,1H3,(H,22,23,24)(H2,25,26,29,30)/t21-/m1/s1 JXDVPBBUPYQRGT-OAQYLSRUSA-N 50332284 (R)-5-((3H-imidazo[4,5-b]pyridin-6-yl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1287852 Disintegrin and metalloproteinase domain-containing protein 17 0.920000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332284 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332284&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52941225 123111399 CHEMBL1287852 ZINC64559288 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611987 CCN1CCN(Cc2ccc(cc2)C#C[C@]2(CN3Cc4ccc(OC)cc4C3=O)NC(=O)NC2=O)CC1 InChI=1S/C28H31N5O4/c1-3-31-12-14-32(15-13-31)17-21-6-4-20(5-7-21)10-11-28(26(35)29-27(36)30-28)19-33-18-22-8-9-23(37-2)16-24(22)25(33)34/h4-9,16H,3,12-15,17-19H2,1-2H3,(H2,29,30,35,36)/t28-/m1/s1 SISZTYKGUNKWOD-MUUNZHRXSA-N 50332285 (R)-5-((4-((4-ethylpiperazin-1-yl)methyl)phenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1287881::US8541572, 515 Disintegrin and metalloproteinase domain-containing protein 17 0.290000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332285 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332285&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52947303 123111400 CHEMBL1287881 ZINC64559000 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611988 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)N3CCNCC3)C(=O)c2c1 InChI=1S/C25H25N5O4/c1-34-20-7-4-18-15-30(22(31)21(18)14-20)16-25(23(32)27-24(33)28-25)9-8-17-2-5-19(6-3-17)29-12-10-26-11-13-29/h2-7,14,26H,10-13,15-16H2,1H3,(H2,27,28,32,33)/t25-/m1/s1 PYTXPVHJIDYQEO-RUZDIDTESA-N 102773 CHEMBL1287882::US8541572, 2203 Disintegrin and metalloproteinase domain-containing protein 17 0.610000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102773 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102773&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52949743 172098064 CHEMBL1287882 ZINC96173672 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611989 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(CC4CCN(C)CC4)nc3)C(=O)c2c1 InChI=1S/C27H29N5O4/c1-31-11-8-18(9-12-31)13-21-5-3-19(15-28-21)7-10-27(25(34)29-26(35)30-27)17-32-16-20-4-6-22(36-2)14-23(20)24(32)33/h3-6,14-15,18H,8-9,11-13,16-17H2,1-2H3,(H2,29,30,34,35)/t27-/m1/s1 ATUIUMZYBUFUGD-HHHXNRCGSA-N 50332287 (R)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-5-((6-((1-methylpiperidin-4-yl)methyl)pyridin-3-yl)ethynyl)imidazolidine-2,4-dione::CHEMBL1287908::US8541572, 739 Disintegrin and metalloproteinase domain-containing protein 17 0.470000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332287 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332287&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52944849 123111402 CHEMBL1287908 ZINC64559389 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611990 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(CN=O)cc3)C(=O)c2c1 InChI=1S/C22H18N4O5/c1-31-17-7-6-16-12-26(19(27)18(16)10-17)13-22(20(28)24-21(29)25-22)9-8-14-2-4-15(5-3-14)11-23-30/h2-7,10H,11-13H2,1H3,(H2,24,25,28,29)/t22-/m1/s1 NHJFUEUFHUNKDT-JOCHJYFZSA-N 50332288 (R)-4-((4-((6-methoxy-1-oxoisoindolin-2-yl)methyl)-2,5-dioxoimidazolidin-4-yl)ethynyl)benzaldehyde oxime::CHEMBL1287909 Disintegrin and metalloproteinase domain-containing protein 17 0.160000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332288 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332288&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 91933622 123111403 CHEMBL1287909 ZINC64559390 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611991 CCN1CCN(CC1)C(=NO)c1ccc(cc1)C#C[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O InChI=1S/C28H30N6O5/c1-3-32-12-14-33(15-13-32)24(31-38)20-6-4-19(5-7-20)10-11-28(26(36)29-27(37)30-28)18-34-17-21-8-9-22(39-2)16-23(21)25(34)35/h4-9,16,38H,3,12-15,17-18H2,1-2H3,(H2,29,30,36,37)/t28-/m1/s1 FUKIDORAYBVNQH-MUUNZHRXSA-N 50332289 (R)-5-((4-((4-ethylpiperazin-1-yl)(hydroxyimino)methyl)phenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1287939 Disintegrin and metalloproteinase domain-containing protein 17 0.160000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332289 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332289&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52943632 123111404 CHEMBL1287939 ZINC64559336 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611992 CCN1CCN(CC1)C(=NO)c1ccc(cn1)C#C[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O InChI=1S/C27H29N7O5/c1-3-32-10-12-33(13-11-32)23(31-38)22-7-4-18(15-28-22)8-9-27(25(36)29-26(37)30-27)17-34-16-19-5-6-20(39-2)14-21(19)24(34)35/h4-7,14-15,38H,3,10-13,16-17H2,1-2H3,(H2,29,30,36,37)/t27-/m1/s1 WFCALHCUTXXTKL-HHHXNRCGSA-N 50332290 (R)-5-((6-((4-ethylpiperazin-1-yl)(hydroxyimino)methyl)pyridin-3-yl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1287969 Disintegrin and metalloproteinase domain-containing protein 17 0.180000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332290 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332290&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52943659 123111405 CHEMBL1287969 ZINC64548861 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611993 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)C(=NO)N3CCN(C)CC3)C(=O)c2c1 InChI=1S/C27H28N6O5/c1-31-11-13-32(14-12-31)23(30-37)19-5-3-18(4-6-19)9-10-27(25(35)28-26(36)29-27)17-33-16-20-7-8-21(38-2)15-22(20)24(33)34/h3-8,15,37H,11-14,16-17H2,1-2H3,(H2,28,29,35,36)/t27-/m1/s1 KOKJKBHDHWXBDP-HHHXNRCGSA-N 50332291 (R)-5-((4-((hydroxyimino)(4-methylpiperazin-1-yl)methyl)phenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1287999 Disintegrin and metalloproteinase domain-containing protein 17 0.220000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332291 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332291&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52942472 123111406 CHEMBL1287999 ZINC64559316 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611994 COc1ccc2CN(C[C@]3(NC(=O)NC3=O)C#Cc3ccc(cc3)-c3ncccc3O)C(=O)c2c1 InChI=1S/C26H20N4O5/c1-35-19-9-8-18-14-30(23(32)20(18)13-19)15-26(24(33)28-25(34)29-26)11-10-16-4-6-17(7-5-16)22-21(31)3-2-12-27-22/h2-9,12-13,31H,14-15H2,1H3,(H2,28,29,33,34)/t26-/m1/s1 AUWCRYUPRHMNCJ-AREMUKBSSA-N 50332292 (R)-5-((4-(3-hydroxypyridin-2-yl)phenyl)ethynyl)-5-((6-methoxy-1-oxoisoindolin-2-yl)methyl)imidazolidine-2,4-dione::CHEMBL1288000::US8541572, 934 Disintegrin and metalloproteinase domain-containing protein 17 0.070000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332292 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332292&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52941250 123111407 CHEMBL1288000 ZINC64559146 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50611995 CCN1CCN(CC1)c1ccc(O)c(n1)-c1ccc(cc1F)C#C[C@]1(CN2Cc3ccc(OC)cc3C2=O)NC(=O)NC1=O InChI=1S/C32H31FN6O5/c1-3-37-12-14-38(15-13-37)27-9-8-26(40)28(34-27)23-7-4-20(16-25(23)33)10-11-32(30(42)35-31(43)36-32)19-39-18-21-5-6-22(44-2)17-24(21)29(39)41/h4-9,16-17,40H,3,12-15,18-19H2,1-2H3,(H2,35,36,42,43)/t32-/m1/s1 NSKDLLYTWJVRPJ-JGCGQSQUSA-N 102669 CHEMBL1288726::US8541572, 976 Disintegrin and metalloproteinase domain-containing protein 17 0.100000 ChEMBL 10.1016/j.bmcl.2010.10.081 10.7270/Q2Z89CP0 21106451 Girijavallabhan, VM; Chen, L; Dai, C; Feltz, RJ; Firmansjah, L; Li, D; Kim, SH; Kozlowski, JA; Lavey, BJ; Kosinski, A; Piwinski, JJ; Popovici-Muller, J; Rizvi, R; Rosner, KE; Shankar, BB; Shih, NY; Siddiqui, MA; Tong, L; Wong, MK; Yang, DY; Yang, L; Yu, W; Zhou, G; Guo, Z; Orth, P; Madison, V; Bian, H; Lundell, D; Niu, X; Shah, H; Sun, J; Umland, S Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=102669 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=102669&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46199152 172097960 CHEMBL1288726 ZINC96173555 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625302 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2ncc(cc2C)C(F)(F)F)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C25H33F4N5O4S/c1-17-10-20(25(27,28)29)12-30-22(17)5-4-19-6-8-33(9-7-19)39(37,38)15-24(3,34(36)16-35)11-18(2)23-31-13-21(26)14-32-23/h10,12-14,16,18-19,36H,4-9,11,15H2,1-3H3/t18-,24-/m0/s1 SVXOKXGEZUGFFS-UUOWRZLLSA-N 50337740 CHEMBL1683463::N-((2S,4S)-4-(5-fluoropyrimidin-2-yl)-2-methyl-1-(4-(2-(3-methyl-5-(trifluoromethyl)pyridin-2-yl)ethyl)piperidin-1-ylsulfonyl)pentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8p Disintegrin and metalloproteinase domain-containing protein 17 24000 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337740 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337740&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53326761 125087842 CHEMBL1683463 ZINC66078484 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50625305 C[C@@H](C[C@@](C)(CS(=O)(=O)N1CCC(CCc2ncc(cc2Cl)C(F)(F)F)CC1)N(O)C=O)c1ncc(F)cn1 InChI=1S/C24H30ClF4N5O4S/c1-16(22-31-12-19(26)13-32-22)10-23(2,34(36)15-35)14-39(37,38)33-7-5-17(6-8-33)3-4-21-20(25)9-18(11-30-21)24(27,28)29/h9,11-13,15-17,36H,3-8,10,14H2,1-2H3/t16-,23-/m0/s1 WTIUPHRWVGHPRH-HJPURHCSSA-N 50337741 CHEMBL1683462::N-((2S,4S)-1-(4-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)ethyl)piperidin-1-ylsulfonyl)-4-(5-fluoropyrimidin-2-yl)-2-methylpentan-2-yl)-N-hydroxyformamide::US10322143, Compound 8o Disintegrin and metalloproteinase domain-containing protein 17 27000 ChEMBL 10.1016/j.bmcl.2011.01.036 10.7270/Q2DV1K5M 21300546 De Savi, C; Pape, A; Cumming, JG; Ting, A; Smith, PD; Burrows, JN; Mills, M; Davies, C; Lamont, S; Milne, D; Cook, C; Moore, P; Sawyer, Y; Gerhardt, S AstraZeneca http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50337741 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50337741&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53320226 125087843 CHEMBL1683462 ZINC66077844 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612323 Cc1ccc2oc(=O)c(CC(CCc3ccc(O)cc3)C(=O)NO)cc2c1 InChI=1S/C21H21NO5/c1-13-2-9-19-16(10-13)12-17(21(25)27-19)11-15(20(24)22-26)6-3-14-4-7-18(23)8-5-14/h2,4-5,7-10,12,15,23,26H,3,6,11H2,1H3,(H,22,24) OKJLVTXXSSQVIG-UHFFFAOYSA-N 50332470 CHEMBL1630100::N-Hydroxy-4-(4-hydroxyphenyl)-2-((6-methyl-2-oxo-2H-chromen-3-yl)methyl)butan-amide Disintegrin and metalloproteinase domain-containing protein 17 0.300000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332470 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332470&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986115 125082572 CHEMBL1630100 ZINC34851466 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612324 Cc1ccc2oc(=O)c(CC(Cc3ccc(OCCN4CCCCC4)cc3)C(=O)NO)cc2c1 InChI=1S/C27H32N2O5/c1-19-5-10-25-21(15-19)17-23(27(31)34-25)18-22(26(30)28-32)16-20-6-8-24(9-7-20)33-14-13-29-11-3-2-4-12-29/h5-10,15,17,22,32H,2-4,11-14,16,18H2,1H3,(H,28,30) ARCRXGOGDAPKEY-UHFFFAOYSA-N 50332471 3-(6-Methyl-2-oxo-2H-chromen-3-yl)-2-(4-(2-(piperidin-1-yl)ethoxy)benzyl)propanoic acid hydroxyamide::CHEMBL1630101 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332471 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332471&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986512 125082573 CHEMBL1630101 ZINC34852263 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612325 Cc1ccc2oc(=O)c(CC(Cc3cccc(OCCN4CCCCC4)c3)C(=O)NO)cc2c1 InChI=1S/C27H32N2O5/c1-19-8-9-25-21(14-19)17-23(27(31)34-25)18-22(26(30)28-32)15-20-6-5-7-24(16-20)33-13-12-29-10-3-2-4-11-29/h5-9,14,16-17,22,32H,2-4,10-13,15,18H2,1H3,(H,28,30) IJISOXVPVQWLAY-UHFFFAOYSA-N 50332472 3-(6-Methyl-2-oxo-2H-chromen-3-yl)-2-(3-(2-(piperidin-1-yl)ethoxy)benzyl)propanoic acid hydroxyamide::CHEMBL1630102 Disintegrin and metalloproteinase domain-containing protein 17 1.1 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986703 125082574 CHEMBL1630102 ZINC34852705 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612326 Cc1ccc2oc(=O)c(CC(CCc3ccc(OCCN4CCCCC4)cc3)C(=O)NO)cc2c1 InChI=1S/C28H34N2O5/c1-20-5-12-26-23(17-20)19-24(28(32)35-26)18-22(27(31)29-33)9-6-21-7-10-25(11-8-21)34-16-15-30-13-3-2-4-14-30/h5,7-8,10-12,17,19,22,33H,2-4,6,9,13-16,18H2,1H3,(H,29,31) GOUYMPANMMVPFE-UHFFFAOYSA-N 50332473 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-4-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-butanoic acid hydroxyamide::CHEMBL1630103 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332473 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332473&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986607 125082575 CHEMBL1630103 ZINC34852490 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612327 Cc1ccc2oc(=O)c(CC(CCc3cccc(OCCN4CCCCC4)c3)C(=O)NO)cc2c1 InChI=1S/C28H34N2O5/c1-20-8-11-26-23(16-20)19-24(28(32)35-26)18-22(27(31)29-33)10-9-21-6-5-7-25(17-21)34-15-14-30-12-3-2-4-13-30/h5-8,11,16-17,19,22,33H,2-4,9-10,12-15,18H2,1H3,(H,29,31) MYFAXYOWANOMSJ-UHFFFAOYSA-N 50332474 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-4-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-butanoic acid hydroxyamide::CHEMBL1630104 Disintegrin and metalloproteinase domain-containing protein 17 0.900000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332474 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332474&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53316692 125082576 CHEMBL1630104 ZINC66260208 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612328 Cc1ccc2oc(=O)c(CC(CCCc3ccc(OCCN4CCCCC4)cc3)C(=O)NO)cc2c1 InChI=1S/C29H36N2O5/c1-21-8-13-27-24(18-21)20-25(29(33)36-27)19-23(28(32)30-34)7-5-6-22-9-11-26(12-10-22)35-17-16-31-14-3-2-4-15-31/h8-13,18,20,23,34H,2-7,14-17,19H2,1H3,(H,30,32) JAZDDPKAAYCQHV-UHFFFAOYSA-N 50332475 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-5-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-pentanoic acid hydroxyamide::CHEMBL1630105 Disintegrin and metalloproteinase domain-containing protein 17 1.1 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332475 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332475&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986869 125082577 CHEMBL1630105 ZINC34853085 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612329 Cc1ccc2oc(=O)c(CC(CCCc3cccc(OCCN4CCCCC4)c3)C(=O)NO)cc2c1 InChI=1S/C29H36N2O5/c1-21-11-12-27-24(17-21)20-25(29(33)36-27)19-23(28(32)30-34)9-5-7-22-8-6-10-26(18-22)35-16-15-31-13-3-2-4-14-31/h6,8,10-12,17-18,20,23,34H,2-5,7,9,13-16,19H2,1H3,(H,30,32) RSUMJYYMCXRSNU-UHFFFAOYSA-N 50332476 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-5-(3-(2-(piperidin-1-yl)ethoxy)phenyl)-pentanoic acid hydroxyamide::CHEMBL1630106 Disintegrin and metalloproteinase domain-containing protein 17 0.270 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332476&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986873 125082578 CHEMBL1630106 ZINC34853100 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612330 CN(C)CCOc1ccc(CCC(Cc2cc3cc(C)ccc3oc2=O)C(=O)NO)cc1 InChI=1S/C25H30N2O5/c1-17-4-11-23-20(14-17)16-21(25(29)32-23)15-19(24(28)26-30)8-5-18-6-9-22(10-7-18)31-13-12-27(2)3/h4,6-7,9-11,14,16,19,30H,5,8,12-13,15H2,1-3H3,(H,26,28) WRLLSTLVYRVAEC-UHFFFAOYSA-N 50332477 4-(4-(2-(Dimethylamino)ethoxy)phenyl)-2-((6-methyl-2-oxo-2H-chromen-3-yl)-methyl)butanoic acid hydroxyamide::CHEMBL1630088 Disintegrin and metalloproteinase domain-containing protein 17 0.660 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332477&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986256 125082579 CHEMBL1630088 ZINC34851710 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612331 CCN(CC)CCOc1ccc(CCC(Cc2cc3cc(C)ccc3oc2=O)C(=O)NO)cc1 InChI=1S/C27H34N2O5/c1-4-29(5-2)14-15-33-24-11-8-20(9-12-24)7-10-21(26(30)28-32)17-23-18-22-16-19(3)6-13-25(22)34-27(23)31/h6,8-9,11-13,16,18,21,32H,4-5,7,10,14-15,17H2,1-3H3,(H,28,30) QJCRHWHXKZBHCY-UHFFFAOYSA-N 50332478 4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((6-methyl-2-oxo-2H-chromen-3-yl)-methyl)-butanoic acid hydroxyamide::CHEMBL1630089 Disintegrin and metalloproteinase domain-containing protein 17 0.530000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332478 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332478&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986257 125082580 CHEMBL1630089 ZINC34851713 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612332 CCN(CC)CCOc1ccc(CCC(Cc2cc3ccc(F)cc3oc2=O)C(=O)NO)cc1 InChI=1S/C26H31FN2O5/c1-3-29(4-2)13-14-33-23-11-6-18(7-12-23)5-8-20(25(30)28-32)16-21-15-19-9-10-22(27)17-24(19)34-26(21)31/h6-7,9-12,15,17,20,32H,3-5,8,13-14,16H2,1-2H3,(H,28,30) FESDJRXXBUYBLT-UHFFFAOYSA-N 50332479 4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-fluoro-2-oxo-2H-chromen-3-yl)methyl)-butanoic acid hydroxyamide::CHEMBL1630090 Disintegrin and metalloproteinase domain-containing protein 17 0.460000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332479 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332479&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53320636 125082581 CHEMBL1630090 ZINC66252832 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612333 CCN(CC)CCOc1ccc(CCC(Cc2cc3ccc(C)cc3oc2=O)C(=O)NO)cc1 InChI=1S/C27H34N2O5/c1-4-29(5-2)14-15-33-24-12-8-20(9-13-24)7-11-22(26(30)28-32)18-23-17-21-10-6-19(3)16-25(21)34-27(23)31/h6,8-10,12-13,16-17,22,32H,4-5,7,11,14-15,18H2,1-3H3,(H,28,30) UNOIUBNRWWBQDJ-UHFFFAOYSA-N 50332480 4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-2-oxo-2H-chromen-3-yl)methyl)-butanoic acid hydroxyamide::CHEMBL1630091 Disintegrin and metalloproteinase domain-containing protein 17 0.280000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332480 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332480&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986261 125082582 CHEMBL1630091 ZINC34851725 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612354 CC(C)[C@@H](N1CC[C@](N)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C26H30N4O4/c1-16(2)23(24(31)29-33)30-13-12-26(27,25(30)32)19-8-10-20(11-9-19)34-15-18-14-17(3)28-22-7-5-4-6-21(18)22/h4-11,14,16,23,33H,12-13,15,27H2,1-3H3,(H,29,31)/t23-,26-/m1/s1 VINTZLVANMVXOH-ZEQKJWHPSA-N 50332481 (R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-3-methylbutanamide::CHEMBL1630098 Disintegrin and metalloproteinase domain-containing protein 17 0.100 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332481 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332481&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53320639 125082583 CHEMBL1630098 ZINC38842829 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612355 Cc1ccc2oc(=O)c(CC(Cc3ccccc3)C(=O)NO)cc2c1 InChI=1S/C20H19NO4/c1-13-7-8-18-15(9-13)11-17(20(23)25-18)12-16(19(22)21-24)10-14-5-3-2-4-6-14/h2-9,11,16,24H,10,12H2,1H3,(H,21,22) UOINUECLJZQMHR-UHFFFAOYSA-N 50224961 2-benzyl-N-hydroxy-3-(6-methyl-2-oxo-2H-chromen-3-yl)-propionamide::CHEMBL402030 Disintegrin and metalloproteinase domain-containing protein 17 0.500000 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986113 104096474 CHEMBL402030 ZINC28979017 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50612356 Cc1ccc2oc(=O)c(CC(CCCCc3ccccc3)C(=O)NO)cc2c1 InChI=1S/C23H25NO4/c1-16-11-12-21-19(13-16)15-20(23(26)28-21)14-18(22(25)24-27)10-6-5-9-17-7-3-2-4-8-17/h2-4,7-8,11-13,15,18,27H,5-6,9-10,14H2,1H3,(H,24,25) OORDDBSQINIMJU-UHFFFAOYSA-N 50332482 2-((6-Methyl-2-oxo-2H-chromen-3-yl)methyl)-6-phenylhexanoicacid hydroxyamide::CHEMBL1630099 Disintegrin and metalloproteinase domain-containing protein 17 33 ChEMBL 10.1016/j.bmc.2010.10.006 10.7270/Q2NV9JHW 21078557 Yang, JS; Chun, K; Park, JE; Cho, M; Seo, J; Song, D; Yoon, H; Park, CH; Joe, BY; Choi, JH; Kim, MH; Han, G Yonsei University http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332482 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332482&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15986108 125082584 CHEMBL1630099 ZINC34851448 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637626 CNc1nc(cs1)[C@@H]1N(Cc2ccccc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C27H28N6O4S/c1-16(17-8-10-19(11-9-17)33-13-5-12-29-33)30-25(36)23(34)24(35)26(37)32-14-18-6-3-4-7-20(18)22(32)21-15-38-27(28-2)31-21/h3-13,15-16,22-24,34-35H,14H2,1-2H3,(H,28,31)(H,30,36)/t16-,22-,23-,24-/m1/s1 LOTUNSOIIWVNBG-JUJUEEDWSA-N 50342959 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-1-(2-(methylamino)thiazol-4-yl)isoindolin-2-yl)-4-oxobutanamide::CHEMBL1770826 Disintegrin and metalloproteinase domain-containing protein 17 416 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342959&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587769 131345895 CHEMBL1770826 ZINC43101626 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637627 CNc1nc(cs1)[C@@H]1N(Cc2ccc(F)cc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C27H27FN6O4S/c1-15(16-5-8-19(9-6-16)34-11-3-10-30-34)31-25(37)23(35)24(36)26(38)33-13-17-4-7-18(28)12-20(17)22(33)21-14-39-27(29-2)32-21/h3-12,14-15,22-24,35-36H,13H2,1-2H3,(H,29,32)(H,31,37)/t15-,22-,23-,24-/m1/s1 BPGLVRHHHRCXIG-DVSNZQAGSA-N 50342960 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-6-fluoro-1-(2-(methylamino)thiazol-4-yl)isoindolin-2-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770827 Disintegrin and metalloproteinase domain-containing protein 17 384 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342960&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54585754 131345896 CHEMBL1770827 ZINC71341474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637628 CNc1nc(cs1)[C@@H]1N(Cc2cc(F)ccc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C27H27FN6O4S/c1-15(16-4-7-19(8-5-16)34-11-3-10-30-34)31-25(37)23(35)24(36)26(38)33-13-17-12-18(28)6-9-20(17)22(33)21-14-39-27(29-2)32-21/h3-12,14-15,22-24,35-36H,13H2,1-2H3,(H,29,32)(H,31,37)/t15-,22-,23-,24-/m1/s1 WFIQWYDIJVTQMA-DVSNZQAGSA-N 50342961 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-5-fluoro-1-(2-(methylamino)thiazol-4-yl)isoindolin-2-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770828 Disintegrin and metalloproteinase domain-containing protein 17 288 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586738 131345897 CHEMBL1770828 ZINC71340427 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637629 CCNc1nc(cs1)[C@@H]1N(Cc2nc(N)ncc12)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C26H29N9O4S/c1-3-28-26-33-19(13-40-26)20-17-11-29-25(27)32-18(17)12-34(20)24(39)22(37)21(36)23(38)31-14(2)15-5-7-16(8-6-15)35-10-4-9-30-35/h4-11,13-14,20-22,36-37H,3,12H2,1-2H3,(H,28,33)(H,31,38)(H2,27,29,32)/t14-,20-,21-,22-/m1/s1 XQIHPCLYRSFCFS-ISQWPPNESA-N 50342962 (2R,3R)-4-((R)-2-amino-5-(2-(ethylamino)thiazol-4-yl)-5H-pyrrolo[3,4-d]pyrimidin-6(7H)-yl)-N-((R)-1-(4-(cyclopenta-2,4-dienyl)phenyl)ethyl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770829 Disintegrin and metalloproteinase domain-containing protein 17 257 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342962&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233128 131345898 CHEMBL1770829 ZINC71340487 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637653 COc1cc2CCN(C[C@@H](c3ccccc3)c2cc1OC)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C33H36N4O6/c1-21(22-10-12-25(13-11-22)37-16-7-15-34-37)35-32(40)30(38)31(39)33(41)36-17-14-24-18-28(42-2)29(43-3)19-26(24)27(20-36)23-8-5-4-6-9-23/h4-13,15-16,18-19,21,27,30-31,38-39H,14,17,20H2,1-3H3,(H,35,40)/t21-,27+,30-,31-/m1/s1 JSAOVNMPWWFGKA-ZHPCLXNJSA-N 50342964 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-7,8-dimethoxy-2-phenyl-4,5-dihydro-1H-benzo[d]azepin-3(2H)-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770639 Disintegrin and metalloproteinase domain-containing protein 17 38 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342964&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583814 131345900 CHEMBL1770639 ZINC71332213 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637654 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCCC1c1ccccc1)c1ccc(cc1)-n1cccn1 InChI=1S/C26H30N4O4/c1-18(19-11-13-21(14-12-19)30-17-7-15-27-30)28-25(33)23(31)24(32)26(34)29-16-6-5-10-22(29)20-8-3-2-4-9-20/h2-4,7-9,11-15,17-18,22-24,31-32H,5-6,10,16H2,1H3,(H,28,33)/t18-,22?,23-,24-/m1/s1 ZOKQJQBCYOXVPM-XBMUXEHLSA-N 50342965 CHEMBL1770636::rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-oxo-4-(2-phenylpiperidin-1-yl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342965&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582811 131345901 CHEMBL1770636 ZINC71333801 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637655 COc1cc2CCN(C(c3ccccc3)c2cc1OC)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C32H34N4O6/c1-20(21-10-12-24(13-11-21)36-16-7-15-33-36)34-31(39)29(37)30(38)32(40)35-17-14-23-18-26(41-2)27(42-3)19-25(23)28(35)22-8-5-4-6-9-22/h4-13,15-16,18-20,28-30,37-38H,14,17H2,1-3H3,(H,34,39)/t20-,28?,29-,30-/m1/s1 LWPLUEZJXCPLQV-UHQYVANJSA-N 50342966 CHEMBL1770638::rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-(6,7-dimethoxy-1-phenyl-3,4-dihydroisoquinolin-2(1H)-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 0.900000 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342966&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581885 131345902 CHEMBL1770638 ZINC71341296 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637656 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCCC1c1ccc(Cl)cc1)c1ccc(cc1)-n1cccn1 InChI=1S/C26H29ClN4O4/c1-17(18-8-12-21(13-9-18)31-16-4-14-28-31)29-25(34)23(32)24(33)26(35)30-15-3-2-5-22(30)19-6-10-20(27)11-7-19/h4,6-14,16-17,22-24,32-33H,2-3,5,15H2,1H3,(H,29,34)/t17-,22?,23-,24-/m1/s1 JSERLHVWMSVIHR-WRJCVHQSSA-N 50342967 CHEMBL1770635::rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-(2-(4-chlorophenyl)piperidin-1-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342967&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587743 131345903 CHEMBL1770635 ZINC71341969 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637657 COc1cc2CCN([C@@H](c3ccc(Cl)cc3)c2cc1OC)C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C32H33ClN4O6/c1-19(20-7-11-24(12-8-20)37-15-4-14-34-37)35-31(40)29(38)30(39)32(41)36-16-13-22-17-26(42-2)27(43-3)18-25(22)28(36)21-5-9-23(33)10-6-21/h4-12,14-15,17-19,28-30,38-39H,13,16H2,1-3H3,(H,35,40)/t19-,28+,29-,30-/m1/s1 LELQFMOAGQJJJA-CDAGOOBWSA-N 50342968 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((S)-1-(4-chlorophenyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770637 Disintegrin and metalloproteinase domain-containing protein 17 2.6 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342968&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587744 131345904 CHEMBL1770637 ZINC71333844 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637658 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCCCC1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 InChI=1S/C26H29ClN4O4/c1-17(18-9-11-21(12-10-18)31-15-5-13-28-31)29-25(34)23(32)24(33)26(35)30-14-3-2-8-22(30)19-6-4-7-20(27)16-19/h4-7,9-13,15-17,22-24,32-33H,2-3,8,14H2,1H3,(H,29,34)/t17-,22?,23-,24-/m1/s1 JOZFAGBSZGGXDH-WRJCVHQSSA-N 50342969 CHEMBL1770634::rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-(2-(3-chlorophenyl)piperidin-1-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 87 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342969&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587742 131345905 CHEMBL1770634 ZINC71341680 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637659 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1C[C@H](O)CC1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 InChI=1S/C25H27ClN4O5/c1-15(16-6-8-19(9-7-16)30-11-3-10-27-30)28-24(34)22(32)23(33)25(35)29-14-20(31)13-21(29)17-4-2-5-18(26)12-17/h2-12,15,20-23,31-33H,13-14H2,1H3,(H,28,34)/t15-,20-,21?,22-,23-/m1/s1 LCAPTPZGZUFLDO-SGJWMDMVSA-N 50342970 CHEMBL1770633::rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((4R)-2-(3-chlorophenyl)-4-hydroxypyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 7.6 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342970&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54584787 131345906 CHEMBL1770633 ZINC71342076 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637660 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC[C@H](O)C1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 InChI=1S/C25H27ClN4O5/c1-15(16-6-8-19(9-7-16)30-12-3-11-27-30)28-24(34)22(32)23(33)25(35)29-13-10-20(31)21(29)17-4-2-5-18(26)14-17/h2-9,11-12,14-15,20-23,31-33H,10,13H2,1H3,(H,28,34)/t15-,20+,21?,22-,23-/m1/s1 ZONDWYRVJNIZDM-GWSXGMLESA-N 50342971 CHEMBL1770632::rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((3S)-2-(3-chlorophenyl)-3-hydroxypyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 6.7 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583813 131345907 CHEMBL1770632 ZINC71332882 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637661 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CC=C[C@@H]1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 InChI=1S/C25H25ClN4O4/c1-16(17-8-10-20(11-9-17)30-14-4-12-27-30)28-24(33)22(31)23(32)25(34)29-13-3-7-21(29)18-5-2-6-19(26)15-18/h2-12,14-16,21-23,31-32H,13H2,1H3,(H,28,33)/t16-,21-,22-,23-/m1/s1 GZGYPOLQWKTPLV-HKDUHGGJSA-N 50342972 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(3-chlorophenyl)-2,5-dihydro-1H-pyrrol-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770631 Disintegrin and metalloproteinase domain-containing protein 17 0.500000 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582810 131345908 CHEMBL1770631 ZINC43101620 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637662 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@]1(C)c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 InChI=1S/C26H29ClN4O4/c1-17(18-8-10-21(11-9-18)31-15-5-13-28-31)29-24(34)22(32)23(33)25(35)30-14-4-12-26(30,2)19-6-3-7-20(27)16-19/h3,5-11,13,15-17,22-23,32-33H,4,12,14H2,1-2H3,(H,29,34)/t17-,22-,23-,26-/m1/s1 PSWJMXOVKOAUDH-VLYKXWEESA-N 50342973 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-methyl-2-phenylpyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770630 Disintegrin and metalloproteinase domain-containing protein 17 0.400000 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342973&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586703 131345909 CHEMBL1770630 ZINC71341486 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637663 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 InChI=1S/C25H27ClN4O4/c1-16(17-8-10-20(11-9-17)30-14-4-12-27-30)28-24(33)22(31)23(32)25(34)29-13-3-7-21(29)18-5-2-6-19(26)15-18/h2,4-6,8-12,14-16,21-23,31-32H,3,7,13H2,1H3,(H,28,33)/t16-,21-,22-,23-/m1/s1 IIBLNMYMPDUKOQ-HKDUHGGJSA-N 50342963 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770629 Disintegrin and metalloproteinase domain-containing protein 17 0.800000 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46856241 131345899 CHEMBL1770629 ZINC68247404 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637664 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccn[nH]1)c1ccc(cc1)-n1cccn1 InChI=1S/C22H26N6O4/c1-14(15-5-7-16(8-6-15)28-13-3-10-24-28)25-21(31)19(29)20(30)22(32)27-12-2-4-18(27)17-9-11-23-26-17/h3,5-11,13-14,18-20,29-30H,2,4,12H2,1H3,(H,23,26)(H,25,31)/t14-,18-,19-,20-/m1/s1 MFBZIXAIGOTFGJ-LMFCIFFHSA-N 50342974 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(1H-pyrazol-3-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770640 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342974&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54584788 131345910 CHEMBL1770640 ZINC71418538 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637665 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccn(C)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C23H28N6O4/c1-15(16-6-8-17(9-7-16)29-13-4-11-24-29)25-22(32)20(30)21(31)23(33)28-12-3-5-19(28)18-10-14-27(2)26-18/h4,6-11,13-15,19-21,30-31H,3,5,12H2,1-2H3,(H,25,32)/t15-,19-,20-,21-/m1/s1 RJLCFLKZMDBPQD-NMSZZDKCSA-N 50342975 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(1-methyl-1H-pyrazol-3-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770641 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583815 131345911 CHEMBL1770641 ZINC71335290 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637666 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1nccs1)c1ccc(cc1)-n1cccn1 InChI=1S/C22H25N5O4S/c1-14(15-5-7-16(8-6-15)27-12-3-9-24-27)25-20(30)18(28)19(29)22(31)26-11-2-4-17(26)21-23-10-13-32-21/h3,5-10,12-14,17-19,28-29H,2,4,11H2,1H3,(H,25,30)/t14-,17-,18-,19-/m1/s1 FPFGKLJJFZLDHL-UTRMSSBJSA-N 50342976 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-oxo-4-((R)-2-(thiazol-2-yl)pyrrolidin-1-yl)butanamide::CHEMBL1770642 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342976&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583816 131345912 CHEMBL1770642 ZINC71341754 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637667 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(C)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C23H27N5O4S/c1-14(16-6-8-17(9-7-16)28-12-4-10-24-28)25-22(31)20(29)21(30)23(32)27-11-3-5-19(27)18-13-33-15(2)26-18/h4,6-10,12-14,19-21,29-30H,3,5,11H2,1-2H3,(H,25,31)/t14-,19-,20-,21-/m1/s1 GJMGFBGQFASNQQ-AVQSHMDHSA-N 50342977 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-methylthiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770643 Disintegrin and metalloproteinase domain-containing protein 17 10 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342977&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586704 131345913 CHEMBL1770643 ZINC71332221 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637668 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(N)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C22H26N6O4S/c1-13(14-5-7-15(8-6-14)28-11-3-9-24-28)25-20(31)18(29)19(30)21(32)27-10-2-4-17(27)16-12-33-22(23)26-16/h3,5-9,11-13,17-19,29-30H,2,4,10H2,1H3,(H2,23,26)(H,25,31)/t13-,17-,18-,19-/m1/s1 HSIRPRQAXKBTSI-BYNBJNPRSA-N 50342940 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-aminothiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770644 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342940 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342940&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586705 131345876 CHEMBL1770644 ZINC71341545 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637669 CNc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C23H28N6O4S/c1-14(15-6-8-16(9-7-15)29-12-4-10-25-29)26-21(32)19(30)20(31)22(33)28-11-3-5-18(28)17-13-34-23(24-2)27-17/h4,6-10,12-14,18-20,30-31H,3,5,11H2,1-2H3,(H,24,27)(H,26,32)/t14-,18-,19-,20-/m1/s1 XOYUIYPTVVQFBX-LMFCIFFHSA-N 50342941 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770645 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342941 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342941&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53232907 131345877 CHEMBL1770645 ZINC71418524 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637670 CCNc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H30N6O4S/c1-3-25-24-28-18(14-35-24)19-6-4-12-29(19)23(34)21(32)20(31)22(33)27-15(2)16-7-9-17(10-8-16)30-13-5-11-26-30/h5,7-11,13-15,19-21,31-32H,3-4,6,12H2,1-2H3,(H,25,28)(H,27,33)/t15-,19-,20-,21-/m1/s1 AZHITYDBWVREAF-NMSZZDKCSA-N 50342942 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(ethylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770646 Disintegrin and metalloproteinase domain-containing protein 17 7 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342942 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342942&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53232908 131345878 CHEMBL1770646 ZINC71332298 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637671 CCCNc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C25H32N6O4S/c1-3-11-26-25-29-19(15-36-25)20-6-4-13-30(20)24(35)22(33)21(32)23(34)28-16(2)17-7-9-18(10-8-17)31-14-5-12-27-31/h5,7-10,12,14-16,20-22,32-33H,3-4,6,11,13H2,1-2H3,(H,26,29)(H,28,34)/t16-,20-,21-,22-/m1/s1 OJMXNABFAINMBJ-XUFNMVPLSA-N 50342943 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-oxo-4-((R)-2-(2-(propylamino)thiazol-4-yl)pyrrolidin-1-yl)butanamide::CHEMBL1770647 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342943 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342943&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233013 131345879 CHEMBL1770647 ZINC71332309 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637672 CC(C)Nc1nc(cs1)[C@H]1CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C25H32N6O4S/c1-15(2)27-25-29-19(14-36-25)20-6-4-12-30(20)24(35)22(33)21(32)23(34)28-16(3)17-7-9-18(10-8-17)31-13-5-11-26-31/h5,7-11,13-16,20-22,32-33H,4,6,12H2,1-3H3,(H,27,29)(H,28,34)/t16-,20-,21-,22-/m1/s1 SLXFUJBJUAFMPC-XUFNMVPLSA-N 50342944 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(isopropylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770648 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342944 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342944&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233014 131345880 CHEMBL1770648 ZINC71341956 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637673 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(NC2CC2)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C25H30N6O4S/c1-15(16-5-9-18(10-6-16)31-13-3-11-26-31)27-23(34)21(32)22(33)24(35)30-12-2-4-20(30)19-14-36-25(29-19)28-17-7-8-17/h3,5-6,9-11,13-15,17,20-22,32-33H,2,4,7-8,12H2,1H3,(H,27,34)(H,28,29)/t15-,20-,21-,22-/m1/s1 PRUCBZGVKSTGBL-FPHUIIFBSA-N 50342945 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(cyclopropylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770649 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342945 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342945&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233015 131345881 CHEMBL1770649 ZINC71331693 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637674 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(NC2CCC2)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C26H32N6O4S/c1-16(17-8-10-19(11-9-17)32-14-4-12-27-32)28-24(35)22(33)23(34)25(36)31-13-3-7-21(31)20-15-37-26(30-20)29-18-5-2-6-18/h4,8-12,14-16,18,21-23,33-34H,2-3,5-7,13H2,1H3,(H,28,35)(H,29,30)/t16-,21-,22-,23-/m1/s1 RIKDCTFOLNLMSX-HKDUHGGJSA-N 50342946 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(cyclobutylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770650 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342946 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342946&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 53233016 131345882 CHEMBL1770650 ZINC71341271 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637675 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(Nc2ccccc2F)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C28H29FN6O4S/c1-17(18-9-11-19(12-10-18)35-15-5-13-30-35)31-26(38)24(36)25(37)27(39)34-14-4-8-23(34)22-16-40-28(33-22)32-21-7-3-2-6-20(21)29/h2-3,5-7,9-13,15-17,23-25,36-37H,4,8,14H2,1H3,(H,31,38)(H,32,33)/t17-,23-,24-,25-/m1/s1 QRDIQZQQVWIMMN-LRGWBYFTSA-N 50342947 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(2-fluorophenylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770651 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587745 131345883 CHEMBL1770651 ZINC71341708 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637676 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(Nc2cccnc2)n1)c1ccc(cc1)-n1cccn1 InChI=1S/C27H29N7O4S/c1-17(18-7-9-20(10-8-18)34-14-4-12-29-34)30-25(37)23(35)24(36)26(38)33-13-3-6-22(33)21-16-39-27(32-21)31-19-5-2-11-28-15-19/h2,4-5,7-12,14-17,22-24,35-36H,3,6,13H2,1H3,(H,30,37)(H,31,32)/t17-,22-,23-,24-/m1/s1 ZAHVPBWMKQVFIS-SFUZCSOBSA-N 50342948 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-oxo-4-((R)-2-(2-(pyridin-3-ylamino)thiazol-4-yl)pyrrolidin-1-yl)butanamide::CHEMBL1770652 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342948 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342948&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581886 131345884 CHEMBL1770652 ZINC71341871 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637677 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(n1)N(C)C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H30N6O4S/c1-15(16-7-9-17(10-8-16)30-13-5-11-25-30)26-22(33)20(31)21(32)23(34)29-12-4-6-19(29)18-14-35-24(27-18)28(2)3/h5,7-11,13-15,19-21,31-32H,4,6,12H2,1-3H3,(H,26,33)/t15-,19-,20-,21-/m1/s1 KNMKWKQDFDIRKE-NMSZZDKCSA-N 50342978 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(2-(dimethylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770653 Disintegrin and metalloproteinase domain-containing protein 17 65 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342978&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582812 131345914 CHEMBL1770653 ZINC71342036 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637678 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1csc(n1)N1CCCCC1)c1ccc(cc1)-n1cccn1 InChI=1S/C27H34N6O4S/c1-18(19-8-10-20(11-9-19)33-16-6-12-28-33)29-25(36)23(34)24(35)26(37)32-15-5-7-22(32)21-17-38-27(30-21)31-13-3-2-4-14-31/h6,8-12,16-18,22-24,34-35H,2-5,7,13-15H2,1H3,(H,29,36)/t18-,22-,23-,24-/m1/s1 PXCHESJMUGWIGT-RKNIQEAPSA-N 50342979 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-oxo-4-((R)-2-(2-(piperidin-1-yl)thiazol-4-yl)pyrrolidin-1-yl)butanamide::CHEMBL1770654 Disintegrin and metalloproteinase domain-containing protein 17 39 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342979&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586706 131345915 CHEMBL1770654 ZINC71333745 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637679 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(C)s1 InChI=1S/C24H30N6O4S/c1-14(16-7-9-17(10-8-16)30-13-5-11-26-30)27-22(33)20(31)21(32)23(34)29-12-4-6-18(29)19-15(2)35-24(25-3)28-19/h5,7-11,13-14,18,20-21,31-32H,4,6,12H2,1-3H3,(H,25,28)(H,27,33)/t14-,18-,20-,21-/m1/s1 MPAFFZGRAQCJND-CVDLLHPYSA-N 50342949 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(5-methyl-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1770816 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342949&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586736 131345885 CHEMBL1770816 ZINC71341517 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637680 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)C1CC1 InChI=1S/C26H32N6O4S/c1-15(16-8-10-18(11-9-16)32-14-4-12-28-32)29-24(35)21(33)22(34)25(36)31-13-3-5-19(31)20-23(17-6-7-17)37-26(27-2)30-20/h4,8-12,14-15,17,19,21-22,33-34H,3,5-7,13H2,1-2H3,(H,27,30)(H,29,35)/t15-,19-,21-,22-/m1/s1 RBUWEWRCEBYIGA-BDRMCPCVSA-N 50342950 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(5-cyclopropyl-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770817 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342950&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586737 131345886 CHEMBL1770817 ZINC71341453 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637681 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)-c1ccc(F)cc1 InChI=1S/C29H31FN6O4S/c1-17(18-8-12-21(13-9-18)36-16-4-14-32-36)33-27(39)24(37)25(38)28(40)35-15-3-5-22(35)23-26(41-29(31-2)34-23)19-6-10-20(30)11-7-19/h4,6-14,16-17,22,24-25,37-38H,3,5,15H2,1-2H3,(H,31,34)(H,33,39)/t17-,22-,24-,25-/m1/s1 BBNUOLZUSOKOOD-WOVIWESZSA-N 50342951 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(5-(4-fluorophenyl)-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770818 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342951&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582833 131345887 CHEMBL1770818 ZINC71341657 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637682 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)C#N InChI=1S/C24H27N7O4S/c1-14(15-6-8-16(9-7-15)31-12-4-10-27-31)28-22(34)20(32)21(33)23(35)30-11-3-5-17(30)19-18(13-25)36-24(26-2)29-19/h4,6-10,12,14,17,20-21,32-33H,3,5,11H2,1-2H3,(H,26,29)(H,28,34)/t14-,17-,20-,21-/m1/s1 HMIRYGSNGVROMG-HZNDTHDVSA-N 50342952 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(5-cyano-2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770819 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342952&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582834 131345888 CHEMBL1770819 ZINC71340485 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637683 CNc1nc([C@H]2CCCN2C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c2ccc(cc2)-n2cccn2)c(s1)S(C)(=O)=O InChI=1S/C24H30N6O6S2/c1-14(15-7-9-16(10-8-15)30-13-5-11-26-30)27-21(33)19(31)20(32)22(34)29-12-4-6-17(29)18-23(38(3,35)36)37-24(25-2)28-18/h5,7-11,13-14,17,19-20,31-32H,4,6,12H2,1-3H3,(H,25,28)(H,27,33)/t14-,17-,19-,20-/m1/s1 QFHBCQAIZQPRLF-SJFSSXKUSA-N 50342953 (2R,3R)-2,3-dihydroxy-4-{(2R)-2-[2-(methylamino)-5-(methylsulfonyl)-1,3-thiazol-4-yl]pyrrolidin-1-yl}-4-oxo-N-{(1R)-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}butanamide::(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(methylamino)-5-(methylsulfonyl)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide::CHEMBL1738754 Disintegrin and metalloproteinase domain-containing protein 17 0.400000 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342953&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 786 3O64 51035425 131345889 CHEMBL1738754 ZINC43101616 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637684 CNc1nc(cs1)C1(C)CCCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H30N6O4S/c1-15(16-6-8-17(9-7-16)30-13-5-11-26-30)27-21(33)19(31)20(32)22(34)29-12-4-10-24(29,2)18-14-35-23(25-3)28-18/h5-9,11,13-15,19-20,31-32H,4,10,12H2,1-3H3,(H,25,28)(H,27,33)/t15-,19-,20-,24?/m1/s1 UVUCYVLTGAIXNQ-MQWYCCBPSA-N 50342954 CHEMBL1770820::Rac-(2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-(2-methyl-2-(2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342954&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583850 131345890 CHEMBL1770820 ZINC71341235 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637685 CCNc1nc(cs1)[C@H]1C[C@@H](C)CN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C25H32N6O4S/c1-4-26-25-29-19(14-36-25)20-12-15(2)13-30(20)24(35)22(33)21(32)23(34)28-16(3)17-6-8-18(9-7-17)31-11-5-10-27-31/h5-11,14-16,20-22,32-33H,4,12-13H2,1-3H3,(H,26,29)(H,28,34)/t15-,16-,20-,21-,22-/m1/s1 SCBKQDHXBDGKCY-ZMWUJFKZSA-N 50342955 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((2R,4R)-2-(2-(ethylamino)thiazol-4-yl)-4-methylpyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770821 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342955&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581923 131345891 CHEMBL1770821 ZINC71341526 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637686 CNc1nc(cs1)[C@H]1CC(F)(F)CN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C23H26F2N6O4S/c1-13(14-4-6-15(7-5-14)31-9-3-8-27-31)28-20(34)18(32)19(33)21(35)30-12-23(24,25)10-17(30)16-11-36-22(26-2)29-16/h3-9,11,13,17-19,32-33H,10,12H2,1-2H3,(H,26,29)(H,28,34)/t13-,17-,18-,19-/m1/s1 ZFHLPUYUQKYDTJ-BYNBJNPRSA-N 50342956 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-4,4-difluoro-2-(2-(methylamino)thiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770822 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581924 131345892 CHEMBL1770822 ZINC71341916 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637687 CNc1nc(cs1)[C@H]1C=CCN1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C23H26N6O4S/c1-14(15-6-8-16(9-7-15)29-12-4-10-25-29)26-21(32)19(30)20(31)22(33)28-11-3-5-18(28)17-13-34-23(24-2)27-17/h3-10,12-14,18-20,30-31H,11H2,1-2H3,(H,24,27)(H,26,32)/t14-,18-,19-,20-/m1/s1 FHKSWOLIQBUJCL-LMFCIFFHSA-N 50342957 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((R)-2-(2-(methylamino)thiazol-4-yl)-2,5-dihydro-1H-pyrrol-1-yl)-4-oxobutanamide::CHEMBL1770823 Disintegrin and metalloproteinase domain-containing protein 17 0.600000 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582835 131345893 CHEMBL1770823 ZINC71405081 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637688 CNc1nc(cs1)[C@H]1C[C@H]2C[C@H]2N1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H28N6O4S/c1-13(14-4-6-16(7-5-14)29-9-3-8-26-29)27-22(33)20(31)21(32)23(34)30-18-10-15(18)11-19(30)17-12-35-24(25-2)28-17/h3-9,12-13,15,18-21,31-32H,10-11H2,1-2H3,(H,25,28)(H,27,33)/t13-,15-,18-,19-,20-,21-/m1/s1 MGJFSYHPCJKUCF-BMSGLIPJSA-N 50342958 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((1R,3R,5R)-3-(2-(methylamino)thiazol-4-yl)-2-azabicyclo[3.1.0]hexan-2-yl)-4-oxobutanamide::CHEMBL1770824 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342958&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582836 131345894 CHEMBL1770824 ZINC71341768 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50637689 CNc1nc(cs1)[C@H]1C[C@@H]2C[C@@H]2N1C(=O)[C@H](O)[C@@H](O)C(=O)N[C@H](C)c1ccc(cc1)-n1cccn1 InChI=1S/C24H28N6O4S/c1-13(14-4-6-16(7-5-14)29-9-3-8-26-29)27-22(33)20(31)21(32)23(34)30-18-10-15(18)11-19(30)17-12-35-24(25-2)28-17/h3-9,12-13,15,18-21,31-32H,10-11H2,1-2H3,(H,25,28)(H,27,33)/t13-,15+,18+,19-,20-,21-/m1/s1 MGJFSYHPCJKUCF-RJCGINTCSA-N 50342980 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-2,3-dihydroxy-4-((1S,3R,5S)-3-(2-(methylamino)thiazol-4-yl)-2-azabicyclo[3.1.0]hexan-2-yl)-4-oxobutanamide::CHEMBL1770825 Disintegrin and metalloproteinase domain-containing protein 17 531 ChEMBL 10.1016/j.bmcl.2011.01.002 10.7270/Q28P60T1 21458257 Dai, C; Li, D; Popovici-Muller, J; Zhao, L; Girijavallabhan, VM; Rosner, KE; Lavey, BJ; Rizvi, R; Shankar, BB; Wong, MK; Guo, Z; Orth, P; Strickland, CO; Sun, J; Niu, X; Chen, S; Kozlowski, JA; Lundell, DJ; Piwinski, JJ; Shih, NY; Siddiqui, MA Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342980&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54584805 131345916 CHEMBL1770825 ZINC71341923 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640331 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1ccncc1C#N InChI=1S/C27H26N4O4/c28-15-21-17-29-13-12-22(21)19-10-8-18(9-11-19)16-30-26(34)24(32)25(33)27(35)31-14-4-7-23(31)20-5-2-1-3-6-20/h1-3,5-6,8-13,17,23-25,32-33H,4,7,14,16H2,(H,30,34)/t23-,24-,25-/m1/s1 SJQXVRGUEYPOEU-UBFVSLLYSA-N 50343949 (2R,3R)-N-(4-(3-cyanopyridin-4-yl)benzyl)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779621 Disintegrin and metalloproteinase domain-containing protein 17 5 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343949 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343949&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581565 131346885 CHEMBL1779621 ZINC71341607 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640332 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1cccs1 InChI=1S/C25H26N2O4S/c28-22(23(29)25(31)27-14-4-8-20(27)18-6-2-1-3-7-18)24(30)26-16-17-10-12-19(13-11-17)21-9-5-15-32-21/h1-3,5-7,9-13,15,20,22-23,28-29H,4,8,14,16H2,(H,26,30)/t20-,22-,23-/m1/s1 CBXDOGJFBOSHAQ-YMPZKCBVSA-N 50343950 (2R,3R)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)-N-(4-(thiophen-2-yl)benzyl)butanamide::CHEMBL1779622 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343950 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343950&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54584509 131346886 CHEMBL1779622 ZINC71334257 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640333 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1ccsc1 InChI=1S/C25H26N2O4S/c28-22(23(29)25(31)27-13-4-7-21(27)19-5-2-1-3-6-19)24(30)26-15-17-8-10-18(11-9-17)20-12-14-32-16-20/h1-3,5-6,8-12,14,16,21-23,28-29H,4,7,13,15H2,(H,26,30)/t21-,22-,23-/m1/s1 NKWXCGAGOWWEKI-DNVJHFABSA-N 50343951 (2R,3R)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)-N-(4-(thiophen-3-yl)benzyl)butanamide::CHEMBL1779623 Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343951 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343951&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583529 131346887 CHEMBL1779623 ZINC71340576 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640334 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1ccsc1C#N InChI=1S/C26H25N3O4S/c27-15-22-20(12-14-34-22)18-10-8-17(9-11-18)16-28-25(32)23(30)24(31)26(33)29-13-4-7-21(29)19-5-2-1-3-6-19/h1-3,5-6,8-12,14,21,23-24,30-31H,4,7,13,16H2,(H,28,32)/t21-,23-,24-/m1/s1 XSCNNNHNWAMXEJ-GMKZXUHWSA-N 50343952 (2R,3R)-N-(4-(2-cyanothiophen-3-yl)benzyl)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779624 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343952 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343952&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582564 131346888 CHEMBL1779624 ZINC71334197 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640335 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1ccon1 InChI=1S/C24H25N3O5/c28-21(22(29)24(31)27-13-4-7-20(27)18-5-2-1-3-6-18)23(30)25-15-16-8-10-17(11-9-16)19-12-14-32-26-19/h1-3,5-6,8-12,14,20-22,28-29H,4,7,13,15H2,(H,25,30)/t20-,21-,22-/m1/s1 QPPFZYFEMYRULM-YPAWHYETSA-N 50343953 (2R,3R)-2,3-dihydroxy-N-(4-(isoxazol-3-yl)benzyl)-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779625 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343953 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343953&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54584510 131346889 CHEMBL1779625 ZINC71331182 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640336 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(cc1)-c1csnn1 InChI=1S/C23H23ClN4O4S/c24-17-4-1-3-16(11-17)19-5-2-10-28(19)23(32)21(30)20(29)22(31)25-12-14-6-8-15(9-7-14)18-13-33-27-26-18/h1,3-4,6-9,11,13,19-21,29-30H,2,5,10,12H2,(H,25,31)/t19?,20-,21-/m1/s1 SPQHREUOQGSXDC-RWLBOTFQSA-N 50343954 CHEMBL1777832::rac-(2R,3R)-N-(4-(1,2,3-thiadiazol-4-yl)benzyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343954 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343954&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583579 131346890 CHEMBL1777832 ZINC71332463 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640337 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(cc1)-c1cscn1 InChI=1S/C24H24ClN3O4S/c25-18-4-1-3-17(11-18)20-5-2-10-28(20)24(32)22(30)21(29)23(31)26-12-15-6-8-16(9-7-15)19-13-33-14-27-19/h1,3-4,6-9,11,13-14,20-22,29-30H,2,5,10,12H2,(H,26,31)/t20?,21-,22-/m1/s1 BPPYDGBKCQJTDJ-HRUVVLKGSA-N 50343955 CHEMBL1779626::rac-(2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(4-(thiazol-4-yl)benzyl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 18 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343955 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343955&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587442 131346891 CHEMBL1779626 ZINC71334773 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640338 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(cc1)-c1nccs1 InChI=1S/C24H24ClN3O4S/c25-18-4-1-3-17(13-18)19-5-2-11-28(19)24(32)21(30)20(29)22(31)27-14-15-6-8-16(9-7-15)23-26-10-12-33-23/h1,3-4,6-10,12-13,19-21,29-30H,2,5,11,14H2,(H,27,31)/t19?,20-,21-/m1/s1 UPMBREJNUQUXSR-RWLBOTFQSA-N 50343956 CHEMBL1779627::rac-(2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-(4-(thiazol-2-yl)benzyl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 74 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343956 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343956&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582565 131346892 CHEMBL1779627 ZINC71341622 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640339 Cc1nc2ccccc2n1-c1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccc(Cl)c2)cc1 InChI=1S/C29H29ClN4O4/c1-18-32-23-8-2-3-9-25(23)34(18)22-13-11-19(12-14-22)17-31-28(37)26(35)27(36)29(38)33-15-5-10-24(33)20-6-4-7-21(30)16-20/h2-4,6-9,11-14,16,24,26-27,35-36H,5,10,15,17H2,1H3,(H,31,37)/t24?,26-,27-/m1/s1 RYVDXBBSZXFYKP-HUHKAINZSA-N 50343957 CHEMBL1779628::rac-(2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-N-(4-(2-methyl-1H-benzo[d]imidazol-1-yl)benzyl)-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 296 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343957 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343957&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54584511 131346893 CHEMBL1779628 ZINC71341124 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640340 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(cc1)-n1ccnc1 InChI=1S/C24H25ClN4O4/c25-18-4-1-3-17(13-18)20-5-2-11-29(20)24(33)22(31)21(30)23(32)27-14-16-6-8-19(9-7-16)28-12-10-26-15-28/h1,3-4,6-10,12-13,15,20-22,30-31H,2,5,11,14H2,(H,27,32)/t20?,21-,22-/m1/s1 NYBABYXZJXGVBV-HRUVVLKGSA-N 50343958 CHEMBL1779629::rac-(2R,3R)-N-(4-(1H-imidazol-1-yl)benzyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 270 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343958 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343958&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586423 131346894 CHEMBL1779629 ZINC71332719 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640341 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(cc1)-n1cccn1 InChI=1S/C24H25ClN4O4/c25-18-5-1-4-17(14-18)20-6-2-12-28(20)24(33)22(31)21(30)23(32)26-15-16-7-9-19(10-8-16)29-13-3-11-27-29/h1,3-5,7-11,13-14,20-22,30-31H,2,6,12,15H2,(H,26,32)/t20?,21-,22-/m1/s1 BXLWVAKSQMYQKF-HRUVVLKGSA-N 50343959 CHEMBL1779630::rac-(2R,3R)-N-(4-(1H-pyrazol-1-yl)benzyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343959 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343959&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46919610 131346895 CHEMBL1779630 ZINC71341353 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640350 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1ccc(Cc2ccccc2Cl)s1 InChI=1S/C26H26Cl2N2O4S/c27-18-7-3-6-17(13-18)22-9-4-12-30(22)26(34)24(32)23(31)25(33)29-15-20-11-10-19(35-20)14-16-5-1-2-8-21(16)28/h1-3,5-8,10-11,13,22-24,31-32H,4,9,12,14-15H2,(H,29,33)/t22-,23-,24-/m1/s1 QJJJSNAMXUUQGO-WXFUMESZSA-N 50343960 (2R,3R)-N-((5-(2-chlorobenzyl)thiophen-2-yl)methyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1779595 Disintegrin and metalloproteinase domain-containing protein 17 9.3 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343960 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343960&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583526 131346896 CHEMBL1779595 ZINC71340858 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640351 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1ccc(Cc2cccc(Cl)c2)s1 InChI=1S/C26H26Cl2N2O4S/c27-18-6-1-4-16(12-18)13-20-9-10-21(35-20)15-29-25(33)23(31)24(32)26(34)30-11-3-8-22(30)17-5-2-7-19(28)14-17/h1-2,4-7,9-10,12,14,22-24,31-32H,3,8,11,13,15H2,(H,29,33)/t22-,23-,24-/m1/s1 RDUHYELMPPBCIZ-WXFUMESZSA-N 50343961 (2R,3R)-N-((5-(3-chlorobenzyl)thiophen-2-yl)methyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1779596 Disintegrin and metalloproteinase domain-containing protein 17 48 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343961 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343961&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54585452 131346897 CHEMBL1779596 ZINC71334142 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640352 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1ccc(Cc2ccc(Cl)cc2)s1 InChI=1S/C26H26Cl2N2O4S/c27-18-8-6-16(7-9-18)13-20-10-11-21(35-20)15-29-25(33)23(31)24(32)26(34)30-12-2-5-22(30)17-3-1-4-19(28)14-17/h1,3-4,6-11,14,22-24,31-32H,2,5,12-13,15H2,(H,29,33)/t22-,23-,24-/m1/s1 XLNMIZGBZLNWEW-WXFUMESZSA-N 50343962 (2R,3R)-N-((5-(4-chlorobenzyl)thiophen-2-yl)methyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1779597 Disintegrin and metalloproteinase domain-containing protein 17 37 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343962 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343962&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582559 131346898 CHEMBL1779597 ZINC71331765 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640353 COc1ccccc1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCC[C@@H]2c2cccc(Cl)c2)s1 InChI=1S/C27H29ClN2O5S/c1-35-23-10-3-2-6-18(23)15-20-11-12-21(36-20)16-29-26(33)24(31)25(32)27(34)30-13-5-9-22(30)17-7-4-8-19(28)14-17/h2-4,6-8,10-12,14,22,24-25,31-32H,5,9,13,15-16H2,1H3,(H,29,33)/t22-,24-,25-/m1/s1 NZPYWYNYKTVXIG-QLBJFCOMSA-N 50343963 (2R,3R)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-N-((5-(2-methoxybenzyl)thiophen-2-yl)methyl)-4-oxobutanamide::CHEMBL1779598 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586417 131346899 CHEMBL1779598 ZINC71333638 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640354 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1ccc(Cc2ccsc2)s1 InChI=1S/C24H25ClN2O4S2/c25-17-4-1-3-16(12-17)20-5-2-9-27(20)24(31)22(29)21(28)23(30)26-13-19-7-6-18(33-19)11-15-8-10-32-14-15/h1,3-4,6-8,10,12,14,20-22,28-29H,2,5,9,11,13H2,(H,26,30)/t20-,21-,22-/m1/s1 JYOSRYVNCDIZDP-YPAWHYETSA-N 50343964 (2R,3R)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-((5-(thiophen-3-ylmethyl)thiophen-2-yl)methyl)butanamide::CHEMBL1779599 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343964 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343964&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586418 131346900 CHEMBL1779599 ZINC71333686 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640355 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1ccc(Cn2ccnc2)s1 InChI=1S/C23H25ClN4O4S/c24-16-4-1-3-15(11-16)19-5-2-9-28(19)23(32)21(30)20(29)22(31)26-12-17-6-7-18(33-17)13-27-10-8-25-14-27/h1,3-4,6-8,10-11,14,19-21,29-30H,2,5,9,12-13H2,(H,26,31)/t19-,20-,21-/m1/s1 YKRFVVAVWAADJP-NJDAHSKKSA-N 50343965 (2R,3R)-N-((5-((1H-imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1779600 Disintegrin and metalloproteinase domain-containing protein 17 37 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343965 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343965&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582560 131346901 CHEMBL1779600 ZINC71333580 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640356 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCC[C@@H]2c2cccc(Cl)c2)s1 InChI=1S/C28H29ClN4O4S/c1-17-31-22-8-2-3-9-24(22)33(17)16-21-12-11-20(38-21)15-30-27(36)25(34)26(35)28(37)32-13-5-10-23(32)18-6-4-7-19(29)14-18/h2-4,6-9,11-12,14,23,25-26,34-35H,5,10,13,15-16H2,1H3,(H,30,36)/t23-,25-,26-/m1/s1 FYWKHBUXBKRZTF-LGPLSSKUSA-N 50343966 (2R,3R)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxobutanamide::CHEMBL1779602 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343966 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343966&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586419 131346902 CHEMBL1779602 ZINC71340924 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640357 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1ccc(Cn2c(nc3ccccc23)C(F)(F)F)s1 InChI=1S/C28H26ClF3N4O4S/c29-17-6-3-5-16(13-17)21-9-4-12-35(21)26(40)24(38)23(37)25(39)33-14-18-10-11-19(41-18)15-36-22-8-2-1-7-20(22)34-27(36)28(30,31)32/h1-3,5-8,10-11,13,21,23-24,37-38H,4,9,12,14-15H2,(H,33,39)/t21-,23-,24-/m1/s1 JSNHRUZOJTYCCL-GMKZXUHWSA-N 50343967 (2R,3R)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-((5-((2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)butanamide::(2R,3R)-4-[(2R)-2-(3-chlorophenyl)pyrrolidin-1-yl]-2,3-dihydroxy-4-oxo-N-[(5-{[2-(trifluoromethyl)-1H-benzimidazol-1-yl]methyl}thiophen-2-yl)methyl]butanamide::CHEMBL1230339 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343967 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343967&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 50X 3LGP 46829300 131346903 CHEMBL1230339 ZINC58639042 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640358 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1cc(Cc2ccccc2)cs1 InChI=1S/C26H27ClN2O4S/c27-20-9-4-8-19(14-20)22-10-5-11-29(22)26(33)24(31)23(30)25(32)28-15-21-13-18(16-34-21)12-17-6-2-1-3-7-17/h1-4,6-9,13-14,16,22-24,30-31H,5,10-12,15H2,(H,28,32)/t22?,23-,24-/m1/s1 DKSGYTMSPMXKJU-HEYJASKDSA-N 50343968 (2R,3R)-N-((4-benzylthiophen-2-yl)methyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1779631 Disintegrin and metalloproteinase domain-containing protein 17 45 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343968 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343968&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587443 131346904 CHEMBL1779631 ZINC71410689 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640359 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)C(=O)NCc1ccc(Cc2ccccc2)s1 InChI=1S/C26H27ClN2O4S/c27-19-9-4-8-18(15-19)22-10-5-13-29(22)26(33)24(31)23(30)25(32)28-16-21-12-11-20(34-21)14-17-6-2-1-3-7-17/h1-4,6-9,11-12,15,22-24,30-31H,5,10,13-14,16H2,(H,28,32)/t22-,23-,24-/m1/s1 IHEGKZYHPRGYTG-WXFUMESZSA-N 50343969 (2R,3R)-N-((5-benzylthiophen-2-yl)methyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1779594 Disintegrin and metalloproteinase domain-containing protein 17 20 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343969 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343969&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587440 131346905 CHEMBL1779594 ZINC71333130 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640360 C[C@@H](NC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1cccc(Cl)c1)c1ccc(cc1)-n1cccn1 InChI=1S/C25H27ClN4O4/c1-16(17-8-10-20(11-9-17)30-14-4-12-27-30)28-24(33)22(31)23(32)25(34)29-13-3-7-21(29)18-5-2-6-19(26)15-18/h2,4-6,8-12,14-16,21-23,31-32H,3,7,13H2,1H3,(H,28,33)/t16-,21-,22-,23-/m1/s1 IIBLNMYMPDUKOQ-HKDUHGGJSA-N 50342963 (2R,3R)-N-((R)-1-(4-(1H-pyrazol-1-yl)phenyl)ethyl)-4-((R)-2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL1770629 Disintegrin and metalloproteinase domain-containing protein 17 0.860000 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50342963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50342963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46856241 131345899 CHEMBL1770629 ZINC68247404 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640368 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccnc2)s1 InChI=1S/C27H29N5O4S/c1-17-30-21-7-2-3-8-23(21)32(17)16-20-11-10-19(37-20)15-29-26(35)24(33)25(34)27(36)31-13-5-9-22(31)18-6-4-12-28-14-18/h2-4,6-8,10-12,14,22,24-25,33-34H,5,9,13,15-16H2,1H3,(H,29,35)/t22?,24-,25-/m1/s1 VLPUVRSYGZOYBD-QJBRXVLMSA-N 50343970 CHEMBL1779603::rac-(2R,3R)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxo-4-(2-(pyridin-3-yl)pyrrolidin-1-yl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343970 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343970&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54585453 131346906 CHEMBL1779603 ZINC71340682 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640369 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccncc2)s1 InChI=1S/C27H29N5O4S/c1-17-30-21-5-2-3-6-23(21)32(17)16-20-9-8-19(37-20)15-29-26(35)24(33)25(34)27(36)31-14-4-7-22(31)18-10-12-28-13-11-18/h2-3,5-6,8-13,22,24-25,33-34H,4,7,14-16H2,1H3,(H,29,35)/t22?,24-,25-/m1/s1 CYDLJEATMMSHLH-QJBRXVLMSA-N 50343971 CHEMBL1779604::rac-(2R,3R)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxo-4-(2-(pyridin-4-yl)pyrrolidin-1-yl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 36 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343971 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343971&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582561 131346907 CHEMBL1779604 ZINC71341139 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640370 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2ccccn2)s1 InChI=1S/C27H29N5O4S/c1-17-30-21-8-2-3-9-23(21)32(17)16-19-12-11-18(37-19)15-29-26(35)24(33)25(34)27(36)31-14-6-10-22(31)20-7-4-5-13-28-20/h2-5,7-9,11-13,22,24-25,33-34H,6,10,14-16H2,1H3,(H,29,35)/t22?,24-,25-/m1/s1 VUWGWIHIMXGVLJ-QJBRXVLMSA-N 50343972 CHEMBL1779605::rac-(2R,3R)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxo-4-(2-(pyridin-2-yl)pyrrolidin-1-yl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343972 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343972&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54580563 131346908 CHEMBL1779605 ZINC71341406 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640371 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2cccs2)s1 InChI=1S/C26H28N4O4S2/c1-16-28-19-6-2-3-7-20(19)30(16)15-18-11-10-17(36-18)14-27-25(33)23(31)24(32)26(34)29-12-4-8-21(29)22-9-5-13-35-22/h2-3,5-7,9-11,13,21,23-24,31-32H,4,8,12,14-15H2,1H3,(H,27,33)/t21?,23-,24-/m1/s1 BKRSALHFUQRNDH-MXNGKVSJSA-N 50343973 CHEMBL1779606::rac-(2R,3R)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxo-4-(2-(thiophen-2-yl)pyrrolidin-1-yl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343973 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343973&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586420 131346909 CHEMBL1779606 ZINC71332025 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640372 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCCC2c2nccs2)s1 InChI=1S/C25H27N5O4S2/c1-15-28-18-5-2-3-6-19(18)30(15)14-17-9-8-16(36-17)13-27-23(33)21(31)22(32)25(34)29-11-4-7-20(29)24-26-10-12-35-24/h2-3,5-6,8-10,12,20-22,31-32H,4,7,11,13-14H2,1H3,(H,27,33)/t20?,21-,22-/m1/s1 UHOWMAXXCAHFSD-HRUVVLKGSA-N 50343974 CHEMBL1779607::rac-(2R,3R)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxo-4-(2-(thiazol-2-yl)pyrrolidin-1-yl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 9 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343974 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343974&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54580564 131346910 CHEMBL1779607 ZINC71333917 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640373 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2CCC[C@@H]2c2csc(N)n2)s1 InChI=1S/C25H28N6O4S2/c1-14-28-17-5-2-3-6-19(17)31(14)12-16-9-8-15(37-16)11-27-23(34)21(32)22(33)24(35)30-10-4-7-20(30)18-13-36-25(26)29-18/h2-3,5-6,8-9,13,20-22,32-33H,4,7,10-12H2,1H3,(H2,26,29)(H,27,34)/t20-,21-,22-/m1/s1 QPCJRMTVZKFMEM-YPAWHYETSA-N 50343975 (2R,3R)-4-((R)-2-(2-aminothiazol-4-yl)pyrrolidin-1-yl)-2,3-dihydroxy-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxobutanamide::CHEMBL1779608 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343975 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343975&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583527 131346911 CHEMBL1779608 ZINC71340335 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640374 Cc1nc2ccccc2n1Cc1ccc(CNC(=O)[C@H](O)[C@@H](O)C(=O)N2Cc3ccccc3C2)s1 InChI=1S/C26H26N4O4S/c1-16-28-21-8-4-5-9-22(21)30(16)15-20-11-10-19(35-20)12-27-25(33)23(31)24(32)26(34)29-13-17-6-2-3-7-18(17)14-29/h2-11,23-24,31-32H,12-15H2,1H3,(H,27,33)/t23-,24-/m1/s1 JTTWBGCNSJRKAJ-DNQXCXABSA-N 50343976 (2R,3R)-2,3-dihydroxy-4-(isoindolin-2-yl)-N-((5-((2-methyl-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)-4-oxobutanamide::CHEMBL1779609 Disintegrin and metalloproteinase domain-containing protein 17 0.500000 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343976 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343976&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54587441 131346912 CHEMBL1779609 ZINC43101623 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640375 O[C@H]([C@@H](O)C(=O)N1Cc2ccccc2C1)C(=O)NCc1ccc(Cn2c(nc3ccccc23)C(F)(F)F)s1 InChI=1S/C26H23F3N4O4S/c27-26(28,29)25-31-19-7-3-4-8-20(19)33(25)14-18-10-9-17(38-18)11-30-23(36)21(34)22(35)24(37)32-12-15-5-1-2-6-16(15)13-32/h1-10,21-22,34-35H,11-14H2,(H,30,36)/t21-,22-/m1/s1 WUYPHGYWSOTGQB-FGZHOGPDSA-N 50343977 (2R,3R)-2,3-dihydroxy-4-(isoindolin-2-yl)-4-oxo-N-((5-((2-(trifluoromethyl)-1H-benzo[d]imidazol-1-yl)methyl)thiophen-2-yl)methyl)butanamide::CHEMBL1779610 Disintegrin and metalloproteinase domain-containing protein 17 0.200000 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343977 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343977&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54580565 131346913 CHEMBL1779610 ZINC71334588 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640376 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(Cc2ccccc2)cc1 InChI=1S/C28H29ClN2O4/c29-23-9-4-8-22(17-23)24-10-5-15-31(24)28(35)26(33)25(32)27(34)30-18-21-13-11-20(12-14-21)16-19-6-2-1-3-7-19/h1-4,6-9,11-14,17,24-26,32-33H,5,10,15-16,18H2,(H,30,34)/t24?,25-,26-/m1/s1 OELMDIRJWGQCSO-KPRFIHOGSA-N 50309156 (2R,3R)-N-(4-benzylbenzyl)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxobutanamide::CHEMBL601735 Disintegrin and metalloproteinase domain-containing protein 17 70 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309156 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309156&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46229837 104163517 CHEMBL601735 ZINC45372645 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640377 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1ccccc1 InChI=1S/C27H28N2O4/c30-24(25(31)27(33)29-17-7-12-23(29)22-10-5-2-6-11-22)26(32)28-18-19-13-15-21(16-14-19)20-8-3-1-4-9-20/h1-6,8-11,13-16,23-25,30-31H,7,12,17-18H2,(H,28,32)/t23-,24-,25-/m1/s1 PSJYOQDMBWMKPS-UBFVSLLYSA-N 50343978 (2R,3R)-N-(biphenyl-4-ylmethyl)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779611 Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343978 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343978&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586421 131346914 CHEMBL1779611 ZINC38210619 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640378 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1ccccc1C#N InChI=1S/C28H27N3O4/c29-17-22-9-4-5-10-23(22)20-14-12-19(13-15-20)18-30-27(34)25(32)26(33)28(35)31-16-6-11-24(31)21-7-2-1-3-8-21/h1-5,7-10,12-15,24-26,32-33H,6,11,16,18H2,(H,30,34)/t24-,25-,26-/m1/s1 WUEANMGDSFAGIX-TWJOJJKGSA-N 50343979 (2R,3R)-N-((2'-cyanobiphenyl-4-yl)methyl)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779612 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343979 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343979&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54584508 131346915 CHEMBL1779612 ZINC71341103 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640379 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(cn1)-c1ccccc1 InChI=1S/C26H26ClN3O4/c27-20-9-4-8-18(14-20)22-10-5-13-30(22)26(34)24(32)23(31)25(33)29-16-21-12-11-19(15-28-21)17-6-2-1-3-7-17/h1-4,6-9,11-12,14-15,22-24,31-32H,5,10,13,16H2,(H,29,33)/t22?,23-,24-/m1/s1 VHLJYOGZTWEPBQ-HEYJASKDSA-N 50343980 CHEMBL1779613::rac-(2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-((5-phenylpyridin-2-yl)methyl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343980 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343980&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581562 131346916 CHEMBL1779613 ZINC71341100 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640380 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCc1ccc(nc1)-c1ccccc1 InChI=1S/C26H26ClN3O4/c27-20-9-4-8-19(14-20)22-10-5-13-30(22)26(34)24(32)23(31)25(33)29-16-17-11-12-21(28-15-17)18-6-2-1-3-7-18/h1-4,6-9,11-12,14-15,22-24,31-32H,5,10,13,16H2,(H,29,33)/t22?,23-,24-/m1/s1 KFPKPRXWALTBIY-HEYJASKDSA-N 50343981 CHEMBL1779614::rac-(2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-2,3-dihydroxy-4-oxo-N-((6-phenylpyridin-3-yl)methyl)butanamide Disintegrin and metalloproteinase domain-containing protein 17 307 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343981 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343981&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54580566 131346917 CHEMBL1779614 ZINC71333351 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640381 O[C@H]([C@@H](O)C(=O)N1CCCC1c1cccc(Cl)c1)C(=O)NCC1CCN(CC1)c1ccccc1C#N InChI=1S/C27H31ClN4O4/c28-21-7-3-6-19(15-21)23-9-4-12-32(23)27(36)25(34)24(33)26(35)30-17-18-10-13-31(14-11-18)22-8-2-1-5-20(22)16-29/h1-3,5-8,15,18,23-25,33-34H,4,9-14,17H2,(H,30,35)/t23?,24-,25-/m1/s1 VLLNFQMALDCSKE-OPWSDZRHSA-N 50343982 CHEMBL1779615::rac-(2R,3R)-4-(2-(3-chlorophenyl)pyrrolidin-1-yl)-N-((1-(2-cyanophenyl)piperidin-4-yl)methyl)-2,3-dihydroxy-4-oxobutanamide Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343982 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343982&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54586422 131346918 CHEMBL1779615 ZINC71334988 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640382 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCC1C2CN(CC12)c1ccccc1C#N InChI=1S/C27H30N4O4/c28-13-18-9-4-5-10-22(18)30-15-20-19(21(20)16-30)14-29-26(34)24(32)25(33)27(35)31-12-6-11-23(31)17-7-2-1-3-8-17/h1-5,7-10,19-21,23-25,32-33H,6,11-12,14-16H2,(H,29,34)/t19?,20?,21?,23-,24-,25-/m1/s1 FYCCRMRLTSEKNW-BFBAZJPSSA-N 50343983 (2R,3R)-N-((3-(2-cyanophenyl)-3-azabicyclo[3.1.0]hexan-6-yl)methyl)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779616 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343983 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343983&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54583528 131346919 CHEMBL1779616 ZINC71334811 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640383 C[C@@H]1CN(CCC1CNC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccccc1C#N InChI=1S/C28H34N4O4/c1-19-18-31(23-11-6-5-10-21(23)16-29)15-13-22(19)17-30-27(35)25(33)26(34)28(36)32-14-7-12-24(32)20-8-3-2-4-9-20/h2-6,8-11,19,22,24-26,33-34H,7,12-15,17-18H2,1H3,(H,30,35)/t19-,22?,24-,25-,26-/m1/s1 IAOSMUWRBDUJHV-IPGFOAOFSA-N 50343984 (2R,3R)-N-(((3S)-1-(2-cyanophenyl)-3-methylpiperidin-4-yl)methyl)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779617 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343984 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343984&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582562 131346920 CHEMBL1779617 ZINC71331581 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640384 C[C@H]1CN(CCC1CNC(=O)[C@H](O)[C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)c1ccccc1C#N InChI=1S/C28H34N4O4/c1-19-18-31(23-11-6-5-10-21(23)16-29)15-13-22(19)17-30-27(35)25(33)26(34)28(36)32-14-7-12-24(32)20-8-3-2-4-9-20/h2-6,8-11,19,22,24-26,33-34H,7,12-15,17-18H2,1H3,(H,30,35)/t19-,22?,24+,25+,26+/m0/s1 IAOSMUWRBDUJHV-PBTBAKQDSA-N 50343985 (2R,3R)-N-(((3R)-1-(2-cyanophenyl)-3-methylpiperidin-4-yl)methyl)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)butanamide::CHEMBL1779618 Disintegrin and metalloproteinase domain-containing protein 17 315 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343985 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343985&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54582563 131346921 CHEMBL1779618 ZINC71340566 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640385 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1cccnc1 InChI=1S/C26H27N3O4/c30-23(24(31)26(33)29-15-5-9-22(29)20-6-2-1-3-7-20)25(32)28-16-18-10-12-19(13-11-18)21-8-4-14-27-17-21/h1-4,6-8,10-14,17,22-24,30-31H,5,9,15-16H2,(H,28,32)/t22-,23-,24-/m1/s1 BJJLXZDUELMSPM-WXFUMESZSA-N 50343986 (2R,3R)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)-N-(4-(pyridin-3-yl)benzyl)butanamide::CHEMBL1779619 Disintegrin and metalloproteinase domain-containing protein 17 36 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343986 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343986&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581563 131346922 CHEMBL1779619 ZINC71333141 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50640386 O[C@H]([C@@H](O)C(=O)N1CCC[C@@H]1c1ccccc1)C(=O)NCc1ccc(cc1)-c1ccncc1 InChI=1S/C26H27N3O4/c30-23(24(31)26(33)29-16-4-7-22(29)21-5-2-1-3-6-21)25(32)28-17-18-8-10-19(11-9-18)20-12-14-27-15-13-20/h1-3,5-6,8-15,22-24,30-31H,4,7,16-17H2,(H,28,32)/t22-,23-,24-/m1/s1 VKDMDRYKYJWDCY-WXFUMESZSA-N 50343987 (2R,3R)-2,3-dihydroxy-4-oxo-4-((R)-2-phenylpyrrolidin-1-yl)-N-(4-(pyridin-4-yl)benzyl)butanamide::CHEMBL1779620 Disintegrin and metalloproteinase domain-containing protein 17 15 ChEMBL 10.1016/j.bmcl.2010.06.104 10.7270/Q2GX4BWK 20638281 Li, D; Popovici-Muller, J; Belanger, DB; Caldwell, J; Dai, C; David, M; Girijavallabhan, VM; Lavey, BJ; Lee, JF; Liu, Z; Mazzola, R; Rizvi, R; Rosner, KE; Shankar, B; Spitler, J; Ting, PC; Vaccaro, H; Yu, W; Zhou, G; Zhu, Z; Niu, X; Sun, J; Guo, Z; Orth, P; Chen, S; Kozlowski, JA; Lundell, DJ; Madison, V; McKittrick, B; Piwinski, JJ; Shih, NY; Shipps, GW; Siddiqui, MA; Strickland, CO Merck Research Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343987 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343987&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54581564 131346923 CHEMBL1779620 ZINC71340522 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634741 ONC(=O)[C@@H](NCC1CC1)[C@@H](Cc1cccc(O)c1)C(=O)N[C@@H]1[C@H](O)Cc2ccccc12 InChI=1S/C24H29N3O5/c28-17-6-3-4-15(10-17)11-19(22(24(31)27-32)25-13-14-8-9-14)23(30)26-21-18-7-2-1-5-16(18)12-20(21)29/h1-7,10,14,19-22,25,28-29,32H,8-9,11-13H2,(H,26,30)(H,27,31)/t19-,20-,21+,22+/m1/s1 UACUZULRKJKTHE-CZYKHXBRSA-N 50104963 (2S,3R)-2-(cyclopropylmethylamino)-N1-hydroxy-N4-((1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl)-3-(3-hydroxybenzyl)succinamide::(3R)-N~2~-(cyclopropylmethyl)-N~1~-hydroxy-3-(3-hydroxybenzyl)-N~4~-[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-L-aspartamide::(R)-2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydroxy-benzyl)-N*4*-((3S,3aR)-2-hydroxy-indan-1-yl)-succinamide::2-(Cyclopropylmethyl-amino)-N*1*-hydroxy-3-(3-hydroxy-benzyl)-N*4*-(2-hydroxy-indan-1-yl)-succinamide::CHEMBL24398 Disintegrin and metalloproteinase domain-containing protein 17 430 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50104963 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50104963&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 098 3HY9 9954867 104000760 CHEMBL24398 ZINC52957190 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634742 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(s1)-n1cc(Cl)cn1)C(O)=O InChI=1S/C18H16ClN3O4S2/c1-11-16(12-5-3-2-4-6-12)18(11,17(23)24)21-28(25,26)15-8-7-14(27-15)22-10-13(19)9-20-22/h2-11,16,21H,1H3,(H,23,24)/t11-,16-,18+/m1/s1 GRSFKJZRDUZQPW-ONUMYQOESA-N 50311088 CHEMBL1078281::cis-rac-1-(5-(4-chloro-1H-pyrazol-1-yl)thiophene-2-sulfonamido)-2-methyl-3-phenylcyclopropanecarboxylic acid Disintegrin and metalloproteinase domain-containing protein 17 4000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311088 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311088&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46175170 104145449 CHEMBL1078281 ZINC48999878 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634743 COc1cnn(c1)-c1ccc(s1)S(=O)(=O)N[C@]1([C@H](C)[C@@H]1c1ccccc1)C(O)=O InChI=1S/C19H19N3O5S2/c1-12-17(13-6-4-3-5-7-13)19(12,18(23)24)21-29(25,26)16-9-8-15(28-16)22-11-14(27-2)10-20-22/h3-12,17,21H,1-2H3,(H,23,24)/t12-,17-,19+/m1/s1 DSLRBIQFKOUGKT-LLSQANQASA-N 50341816 (1S,2R,3R)-1-[5-(4-Methoxypyrazol-1-yl)thiophene-2-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766899 Disintegrin and metalloproteinase domain-containing protein 17 1600 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341816 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341816&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951967 131344752 CHEMBL1766899 ZINC71319453 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634744 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(s1)-n1cc(C)cn1)C(O)=O InChI=1S/C19H19N3O4S2/c1-12-10-20-22(11-12)15-8-9-16(27-15)28(25,26)21-19(18(23)24)13(2)17(19)14-6-4-3-5-7-14/h3-11,13,17,21H,1-2H3,(H,23,24)/t13-,17-,19+/m1/s1 OJPRZTDTKMGAMY-XVSDVWIESA-N 50341824 (1S,2R,3R)-2-Methyl-1-[5-(4-methylpyrazol-1-yl)thiophene-2-sulfonylamino]-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766900 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341824 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341824&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951968 131344760 CHEMBL1766900 ZINC71316905 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634745 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1ccc(s1)-c1ccc(Cl)cc1)C(O)=O InChI=1S/C21H18ClNO4S2/c1-13-19(15-5-3-2-4-6-15)21(13,20(24)25)23-29(26,27)18-12-11-17(28-18)14-7-9-16(22)10-8-14/h2-13,19,23H,1H3,(H,24,25)/t13-,19-,21+/m1/s1 AHXGZLJBINZPQZ-DYHNYNMBSA-N 50311085 (1S,2R,3R)-1-(5-(4-chlorophenyl)thiophene-2-sulfonamido)-2-methyl-3-phenylcyclopropanecarboxylic acid::CHEMBL1078279 Disintegrin and metalloproteinase domain-containing protein 17 2700 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311085 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311085&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 46882679 104145446 CHEMBL1078279 ZINC49785403 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634746 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2nc3cc(Cl)ccn3c2s1)C(O)=O InChI=1S/C20H16ClN3O4S2/c1-11-17(12-5-3-2-4-6-12)20(11,19(25)26)23-30(27,28)16-10-14-18(29-16)24-8-7-13(21)9-15(24)22-14/h2-11,17,23H,1H3,(H,25,26)/t11-,17-,20+/m1/s1 KFOJCCXBEQXGOL-JSZUHDFRSA-N 50341817 (1S,2R,3R)-1-(6-Chlorothieno[3',2':4,5]imidazo[1,2-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766901 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341817 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341817&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951969 131344753 CHEMBL1766901 ZINC71330287 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634747 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2nn3cc(Cl)ccc3c2s1)C(O)=O InChI=1S/C20H16ClN3O4S2/c1-11-17(12-5-3-2-4-6-12)20(11,19(25)26)23-30(27,28)16-9-14-18(29-16)15-8-7-13(21)10-24(15)22-14/h2-11,17,23H,1H3,(H,25,26)/t11-,17-,20+/m1/s1 QVFLVOHFXMNIFB-JSZUHDFRSA-N 50341818 (1S,2R,3R)-1-(7-Chlorothieno[3',2':3,4]pyrazolo[1,5-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766902 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341818&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951970 131344754 CHEMBL1766902 ZINC71316923 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634748 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2[nH]c3cc(Cl)ccc3c2s1)C(O)=O InChI=1S/C21H17ClN2O4S2/c1-11-18(12-5-3-2-4-6-12)21(11,20(25)26)24-30(27,28)17-10-16-19(29-17)14-8-7-13(22)9-15(14)23-16/h2-11,18,23-24H,1H3,(H,25,26)/t11-,18-,21+/m1/s1 DNSIVPJNRUSHDP-USVHUCMKSA-N 50341819 (1S,2R,3R)-1-(6-Chloro-4H-thieno[3,2-b]indole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766903 Disintegrin and metalloproteinase domain-containing protein 17 3800 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341819 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341819&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951971 131344755 CHEMBL1766903 ZINC71296792 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634749 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2[nH]c3cc(F)ccc3c2s1)C(O)=O InChI=1S/C21H17FN2O4S2/c1-11-18(12-5-3-2-4-6-12)21(11,20(25)26)24-30(27,28)17-10-16-19(29-17)14-8-7-13(22)9-15(14)23-16/h2-11,18,23-24H,1H3,(H,25,26)/t11-,18-,21+/m1/s1 PENUDEJHXUSMIL-USVHUCMKSA-N 50341820 (1S,2R,3R)-1-(6-Fluoro-4H-thieno[3,2-b]indole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766904 Disintegrin and metalloproteinase domain-containing protein 17 1100 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341820 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341820&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951972 131344756 CHEMBL1766904 ZINC71318415 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634750 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)c1cc2[nH]c3ccc(F)cc3c2s1)C(O)=O InChI=1S/C21H17FN2O4S2/c1-11-18(12-5-3-2-4-6-12)21(11,20(25)26)24-30(27,28)17-10-16-19(29-17)14-9-13(22)7-8-15(14)23-16/h2-11,18,23-24H,1H3,(H,25,26)/t11-,18-,21+/m1/s1 FTPFWQRREQUXLQ-USVHUCMKSA-N 50341821 (1S,2R,3R)-1-(7-Fluoro-4H-thieno[3,2-b]indole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766905 Disintegrin and metalloproteinase domain-containing protein 17 1900 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341821&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952074 131344757 CHEMBL1766905 ZINC71318782 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634751 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN(CC1)c1ccc(Cl)cc1)C(O)=O InChI=1S/C21H24ClN3O4S/c1-15-19(16-5-3-2-4-6-16)21(15,20(26)27)23-30(28,29)25-13-11-24(12-14-25)18-9-7-17(22)8-10-18/h2-10,15,19,23H,11-14H2,1H3,(H,26,27)/t15-,19-,21+/m1/s1 GCYXMFHUCWJAKI-VMRPVKRXSA-N 50341822 (1S,2R,3R)-1-[4-(4-Chlorophenyl)piperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766906 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341822 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341822&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952075 131344758 CHEMBL1766906 ZINC71329150 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634752 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCC(=CC1)c1ccc(Cl)cc1)C(O)=O InChI=1S/C22H23ClN2O4S/c1-15-20(18-5-3-2-4-6-18)22(15,21(26)27)24-30(28,29)25-13-11-17(12-14-25)16-7-9-19(23)10-8-16/h2-11,15,20,24H,12-14H2,1H3,(H,26,27)/t15-,20-,22+/m1/s1 XWUCDOCUSPAHFU-QPJICYPMSA-N 50341823 (1S,2R,3R)-1-[4-(4-Chlorophenyl)-1,2,3,6-tetrahydropyridine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766907 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341823 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341823&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952076 131344759 CHEMBL1766907 ZINC71329416 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634753 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(Cl)cc1)C(O)=O InChI=1S/C22H26ClN3O4S/c1-15-14-25(12-13-26(15)19-10-8-18(23)9-11-19)31(29,30)24-22(21(27)28)16(2)20(22)17-6-4-3-5-7-17/h3-11,15-16,20,24H,12-14H2,1-2H3,(H,27,28)/t15-,16-,20-,22+/m1/s1 STTHHFYKRNBSEX-AJYGTSELSA-N 50341786 (1S,2R,3R)-1-[(R)-4-(4-Chlorophenyl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766908 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341786&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952077 131344722 CHEMBL1766908 ZINC71317302 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634754 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@@H](C)C1)c1ccc(Cl)cc1)C(O)=O InChI=1S/C22H26ClN3O4S/c1-15-14-25(12-13-26(15)19-10-8-18(23)9-11-19)31(29,30)24-22(21(27)28)16(2)20(22)17-6-4-3-5-7-17/h3-11,15-16,20,24H,12-14H2,1-2H3,(H,27,28)/t15-,16+,20+,22-/m0/s1 STTHHFYKRNBSEX-LZWBKRQXSA-N 50341787 (1S,2R,3R)-1-[(S)-4-(4-Chlorophenyl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766909 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341787&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952078 131344723 CHEMBL1766909 ZINC71319199 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634755 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(F)cc1)C(O)=O InChI=1S/C22H26FN3O4S/c1-15-14-25(12-13-26(15)19-10-8-18(23)9-11-19)31(29,30)24-22(21(27)28)16(2)20(22)17-6-4-3-5-7-17/h3-11,15-16,20,24H,12-14H2,1-2H3,(H,27,28)/t15-,16-,20-,22+/m1/s1 GDLNLDAXSYMNKX-AJYGTSELSA-N 50341791 (1S,2R,3R)-1-[(R)-4-(4-Fluorophenyl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766913 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341791 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341791&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952273 131344727 CHEMBL1766913 ZINC71315802 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634756 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(s1)C#N)C(O)=O InChI=1S/C21H24N4O4S2/c1-14-13-24(10-11-25(14)18-9-8-17(12-22)30-18)31(28,29)23-21(20(26)27)15(2)19(21)16-6-4-3-5-7-16/h3-9,14-15,19,23H,10-11,13H2,1-2H3,(H,26,27)/t14-,15-,19-,21+/m1/s1 POBFTZWPMIMUSM-HLBGSYOWSA-N 50341793 (1S,2R,3R)-1-[(R)-4-(5-Cyanothiophen-2-yl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766915 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341793 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341793&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952274 131344729 CHEMBL1766915 ZINC71317625 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634757 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1cc(on1)C(F)F)C(O)=O InChI=1S/C20H24F2N4O5S/c1-12-11-25(8-9-26(12)16-10-15(18(21)22)31-23-16)32(29,30)24-20(19(27)28)13(2)17(20)14-6-4-3-5-7-14/h3-7,10,12-13,17-18,24H,8-9,11H2,1-2H3,(H,27,28)/t12-,13-,17-,20+/m1/s1 CZQXANJDCCAOHA-KGIZBLLCSA-N 50341794 (1S,2R,3R)-1-[(R)-4-(5-Difluoromethylisoxazol-3-yl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766916 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341794 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341794&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952275 131344730 CHEMBL1766916 ZINC71296798 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634758 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1cc(on1)C(C)(F)F)C(O)=O InChI=1S/C21H26F2N4O5S/c1-13-12-26(9-10-27(13)17-11-16(32-24-17)20(3,22)23)33(30,31)25-21(19(28)29)14(2)18(21)15-7-5-4-6-8-15/h4-8,11,13-14,18,25H,9-10,12H2,1-3H3,(H,28,29)/t13-,14-,18-,21+/m1/s1 WQDCDSSZTJOWCF-PHAJSTNCSA-N 50341795 (1S,2R,3R)-1-{(R)-4-[5-(1,1-Difluoroethyl)isoxazol-3-yl]-3-methylpiperazine-1-sulfonylamino}-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766917 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341795 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341795&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952276 131344731 CHEMBL1766917 ZINC71330325 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634759 COCc1cc(no1)N1CCN(C[C@H]1C)S(=O)(=O)N[C@]1([C@H](C)[C@@H]1c1ccccc1)C(O)=O InChI=1S/C21H28N4O6S/c1-14-12-24(9-10-25(14)18-11-17(13-30-3)31-22-18)32(28,29)23-21(20(26)27)15(2)19(21)16-7-5-4-6-8-16/h4-8,11,14-15,19,23H,9-10,12-13H2,1-3H3,(H,26,27)/t14-,15-,19-,21+/m1/s1 IUIQYGWNHACUOZ-HLBGSYOWSA-N 50341796 (1S,2R,3R)-1-[(R)-4-(5-Methoxymethylisoxazol-3-yl)-3-methylpiperazine-1-sulfonylamino]-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766918 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341796 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341796&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952277 131344732 CHEMBL1766918 ZINC71318416 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634760 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)cc1cc(Cl)ccc21)C(O)=O InChI=1S/C22H22ClN3O4S/c1-14-20(15-5-3-2-4-6-15)22(14,21(27)28)24-31(29,30)25-9-10-26-18(13-25)12-16-11-17(23)7-8-19(16)26/h2-8,11-12,14,20,24H,9-10,13H2,1H3,(H,27,28)/t14-,20-,22+/m1/s1 NVERRANKYVTEPN-ZFGLAFRWSA-N 50341797 (1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrazino[1,2-a]indole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766919 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341797 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341797&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952388 131344733 CHEMBL1766919 ZINC71296317 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634761 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1cc(Cl)ccc21)C(O)=O InChI=1S/C21H21ClN4O4S/c1-13-19(14-5-3-2-4-6-14)21(13,20(27)28)24-31(29,30)25-9-10-26-17-8-7-15(22)11-16(17)23-18(26)12-25/h2-8,11,13,19,24H,9-10,12H2,1H3,(H,27,28)/t13-,19-,21+/m1/s1 CBZOKXRPUYLLBY-DYHNYNMBSA-N 50341798 (1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766920 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341798 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341798&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951589 131344734 CHEMBL1766920 ZINC71329134 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634762 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(C1)nc1cc(Cl)ccn21)C(O)=O InChI=1S/C21H21ClN4O4S/c1-13-19(14-5-3-2-4-6-14)21(13,20(27)28)24-31(29,30)25-9-8-17-16(12-25)23-18-11-15(22)7-10-26(17)18/h2-7,10-11,13,19,24H,8-9,12H2,1H3,(H,27,28)/t13-,19-,21+/m1/s1 OTCWHHBFFQOWCU-DYHNYNMBSA-N 50341799 (1S,2R,3R)-1-(8-Chloro-1,2,3,4-tetrahydropyrido[3',4':4,5]imidazo[1,2-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766921 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341799 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341799&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952389 131344735 CHEMBL1766921 ZINC71316868 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634763 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)cc1cc(Cl)sc21)C(O)=O InChI=1S/C20H20ClN3O4S2/c1-12-17(13-5-3-2-4-6-13)20(12,19(25)26)22-30(27,28)23-7-8-24-15(11-23)9-14-10-16(21)29-18(14)24/h2-6,9-10,12,17,22H,7-8,11H2,1H3,(H,25,26)/t12-,17-,20+/m1/s1 UWKSANSSQRUVAR-XSXHMXBXSA-N 50341800 (1S,2R,3R)-1-(2-Chloro-5,6,7,8-tetrahydrothieno[3',2':4,5]pyrrolo[1,2-a]pyrazine-7-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1766922 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341800 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341800&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952390 131344736 CHEMBL1766922 ZINC71318400 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634764 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1Cc2nc3cc(Cl)ccn3c2C1)C(O)=O InChI=1S/C20H19ClN4O4S/c1-12-18(13-5-3-2-4-6-13)20(12,19(26)27)23-30(28,29)24-10-15-16(11-24)25-8-7-14(21)9-17(25)22-15/h2-9,12,18,23H,10-11H2,1H3,(H,26,27)/t12-,18-,20+/m1/s1 CPYCKLJBTHKVRT-LIUKBUMOSA-N 50341801 (1S,2R,3R)-1-(6-Chloro-2,3-dihydro-1H-pyrrolo[3',4':4,5]imidazo[1,2-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylic Acid::CHEMBL1767003 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341801 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341801&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951710 131344737 CHEMBL1767003 ZINC71329054 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634765 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1ccccc21)C(O)=O InChI=1S/C21H22N4O4S/c1-14-19(15-7-3-2-4-8-15)21(14,20(26)27)23-30(28,29)24-11-12-25-17-10-6-5-9-16(17)22-18(25)13-24/h2-10,14,19,23H,11-13H2,1H3,(H,26,27)/t14-,19-,21+/m1/s1 OGCHVEMYHSXDJE-MMACOIQUSA-N 50341802 (1S,2R,3R)-2-Methyl-3-phenyl-1-(1,2,3,4-tetrahydropyrazino-[1,2-a]benzimidazole-2-sulfonylamino)cyclopropanecarboxylicAcid::CHEMBL1767004 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341802 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341802&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951473 131344738 CHEMBL1767004 ZINC71329152 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634766 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1cc(F)ccc21)C(O)=O InChI=1S/C21H21FN4O4S/c1-13-19(14-5-3-2-4-6-14)21(13,20(27)28)24-31(29,30)25-9-10-26-17-8-7-15(22)11-16(17)23-18(26)12-25/h2-8,11,13,19,24H,9-10,12H2,1H3,(H,27,28)/t13-,19-,21+/m1/s1 SHSGVWNTSAKSFC-DYHNYNMBSA-N 50341803 (1S,2R,3R)-1-(8-Fluoro-1,2,3,4-tetrahydropyrazino[1,2-a]-benzimidazole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767005 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341803 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341803&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951591 131344739 CHEMBL1767005 ZINC71296776 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634767 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1ccc(F)cc21)C(O)=O InChI=1S/C21H21FN4O4S/c1-13-19(14-5-3-2-4-6-14)21(13,20(27)28)24-31(29,30)25-9-10-26-17-11-15(22)7-8-16(17)23-18(26)12-25/h2-8,11,13,19,24H,9-10,12H2,1H3,(H,27,28)/t13-,19-,21+/m1/s1 HTBWAVKWLNLFGD-DYHNYNMBSA-N 50341804 (1S,2R,3R)-1-(7-Fluoro-1,2,3,4-tetrahydropyrazino[1,2-a]-benzimidazole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767006 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341804&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951593 131344740 CHEMBL1767006 ZINC71316883 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634768 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1cc(ccc21)C#N)C(O)=O InChI=1S/C22H21N5O4S/c1-14-20(16-5-3-2-4-6-16)22(14,21(28)29)25-32(30,31)26-9-10-27-18-8-7-15(12-23)11-17(18)24-19(27)13-26/h2-8,11,14,20,25H,9-10,13H2,1H3,(H,28,29)/t14-,20-,22+/m1/s1 HVPBZXDEMBWXRX-ZFGLAFRWSA-N 50341805 (1S,2R,3R)-1-(8-Cyano-1,2,3,4-tetrahydropyrazino[1,2-a]-benzimidazole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767007 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341805&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951596 131344741 CHEMBL1767007 ZINC71318067 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634769 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1cc(C)ccc21)C(O)=O InChI=1S/C22H24N4O4S/c1-14-8-9-18-17(12-14)23-19-13-25(10-11-26(18)19)31(29,30)24-22(21(27)28)15(2)20(22)16-6-4-3-5-7-16/h3-9,12,15,20,24H,10-11,13H2,1-2H3,(H,27,28)/t15-,20-,22+/m1/s1 LSRFXDADRHAGGZ-QPJICYPMSA-N 50341806 (1S,2R,3R)-2-Methyl-1-(8-methyl-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-2-sulfonylamino)-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767008 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341806&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952492 131344742 CHEMBL1767008 ZINC71318008 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634770 COc1ccc2n3CCN(Cc3nc2c1)S(=O)(=O)N[C@]1([C@H](C)[C@@H]1c1ccccc1)C(O)=O InChI=1S/C22H24N4O5S/c1-14-20(15-6-4-3-5-7-15)22(14,21(27)28)24-32(29,30)25-10-11-26-18-9-8-16(31-2)12-17(18)23-19(26)13-25/h3-9,12,14,20,24H,10-11,13H2,1-2H3,(H,27,28)/t14-,20-,22+/m1/s1 WNPVOXQIWJVANA-ZFGLAFRWSA-N 50341807 (1S,2R,3R)-1-(8-Methoxy-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767009 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341807 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341807&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52951712 131344743 CHEMBL1767009 ZINC71316600 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634771 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(C1)nc1cc(F)ccn21)C(O)=O InChI=1S/C21H21FN4O4S/c1-13-19(14-5-3-2-4-6-14)21(13,20(27)28)24-31(29,30)25-9-8-17-16(12-25)23-18-11-15(22)7-10-26(17)18/h2-7,10-11,13,19,24H,8-9,12H2,1H3,(H,27,28)/t13-,19-,21+/m1/s1 HKMCNRZPOCVMKL-DYHNYNMBSA-N 50341808 (1S,2R,3R)-1-(8-Fluoro-1,2,3,4-tetrahydropyrido[3',4':4,5]imidazo[1,2-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767010 Disintegrin and metalloproteinase domain-containing protein 17 6300 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341808 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341808&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952493 131344744 CHEMBL1767010 ZINC71330376 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634772 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(C1)nn1cc(F)ccc21)C(O)=O InChI=1S/C21H21FN4O4S/c1-13-19(14-5-3-2-4-6-14)21(13,20(27)28)24-31(29,30)25-10-9-16-17(12-25)23-26-11-15(22)7-8-18(16)26/h2-8,11,13,19,24H,9-10,12H2,1H3,(H,27,28)/t13-,19-,21+/m1/s1 KIMAXDZENSBFAC-DYHNYNMBSA-N 50341809 (1S,2R,3R)-1-(7-Fluoro-1,2,3,4-tetrahydropyrido[3'4':3,4]pyrazolo[1,5-a]pyridine-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767011 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341809 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341809&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952597 131344745 CHEMBL1767011 ZINC71329051 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634773 C[C@@H]1[C@H](c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(C1)[nH]c1cc(F)ccc21)C(O)=O InChI=1S/C22H22FN3O4S/c1-13-20(14-5-3-2-4-6-14)22(13,21(27)28)25-31(29,30)26-10-9-17-16-8-7-15(23)11-18(16)24-19(17)12-26/h2-8,11,13,20,24-25H,9-10,12H2,1H3,(H,27,28)/t13-,20-,22+/m1/s1 VFXFWORULVVRDM-YIKPVDIZSA-N 50341810 (1S,2R,3R)-1-(7-Fluoro-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-2-sulfonylamino)-2-methyl-3-phenylcyclopropanecarboxylicAcid::CHEMBL1767012 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341810 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341810&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952598 131344746 CHEMBL1767012 ZINC71319171 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634774 C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCn2c(C1)nc1cc(F)ccc21)C(O)=O InChI=1S/C22H23FN4O4S/c1-14-21(2,15-6-4-3-5-7-15)22(14,20(28)29)25-32(30,31)26-10-11-27-18-9-8-16(23)12-17(18)24-19(27)13-26/h3-9,12,14,25H,10-11,13H2,1-2H3,(H,28,29)/t14-,21-,22-/m1/s1 COXUXHHGASUMFC-KHIBUBOWSA-N 50341811 (1S,2R,3R)-2,3-Dimethyl-1-(8-fluoro-1,2,3,4-tetrahydropyrazino[1,2-a]benzimidazole-2-sulfonylamino)-2-phenylcyclopropanecarboxylicAcid::CHEMBL1767013 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341811 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341811&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952599 131344747 CHEMBL1767013 ZINC71329894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634775 C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(C1)nc1cc(F)ccn21)C(O)=O InChI=1S/C22H23FN4O4S/c1-14-21(2,15-6-4-3-5-7-15)22(14,20(28)29)25-32(30,31)26-10-9-18-17(13-26)24-19-12-16(23)8-11-27(18)19/h3-8,11-12,14,25H,9-10,13H2,1-2H3,(H,28,29)/t14-,21-,22-/m1/s1 RDRCRROFSMSFED-KHIBUBOWSA-N 50341812 (1S,2R,3R)-2.3-Dimethyl-1-(8-fluoro-1,2,3,4-tetrahydropyrido[3',4':4,5]imidazo[1,2-a]pyridine-2-sulfonylamino)-2-phenylcyclopropanecarboxylic Acid::CHEMBL1767014 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341812 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341812&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 50941549 131344748 CHEMBL1767014 ZINC71296734 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634776 C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCc2c(C1)nn1cc(F)ccc21)C(O)=O InChI=1S/C22H23FN4O4S/c1-14-21(2,15-6-4-3-5-7-15)22(14,20(28)29)25-32(30,31)26-11-10-17-18(13-26)24-27-12-16(23)8-9-19(17)27/h3-9,12,14,25H,10-11,13H2,1-2H3,(H,28,29)/t14-,21-,22-/m1/s1 LVVFVQDWLWATBO-KHIBUBOWSA-N 50341813 (1S,2R,3R)-2,3-Dimethyl-1-(7-fluoro-1,2,3,4-tetrahydropyrido[3',4':3,4]pyrazolo[1,5-a]pyridine-2-sulfonylamino)-2-phenylcyclopropanecarboxylic Acid::CHEMBL1767015 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341813 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341813&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952600 131344749 CHEMBL1767015 ZINC71317235 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634777 C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1ccc(s1)C#N)C(O)=O InChI=1S/C22H26N4O4S2/c1-15-14-25(11-12-26(15)19-10-9-18(13-23)31-19)32(29,30)24-22(20(27)28)16(2)21(22,3)17-7-5-4-6-8-17/h4-10,15-16,24H,11-12,14H2,1-3H3,(H,27,28)/t15-,16-,21-,22-/m1/s1 HOFOGNHCTQAGAM-AHWCRGGASA-N 50341814 (1S,2R,3R)-1-[(R)-4-(5-Cyanothiophen-2-yl)-3-methylpiperazine-1-sulfonylamino]-2,3-dimethyl-2-phenylcyclopropanecarboxylicAcid::CHEMBL1767016 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341814 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341814&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952601 131344750 CHEMBL1767016 ZINC71318373 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50634778 C[C@@H]1[C@](C)(c2ccccc2)[C@]1(NS(=O)(=O)N1CCN([C@H](C)C1)c1cc(on1)C(F)F)C(O)=O InChI=1S/C21H26F2N4O5S/c1-13-12-26(9-10-27(13)17-11-16(18(22)23)32-24-17)33(30,31)25-21(19(28)29)14(2)20(21,3)15-7-5-4-6-8-15/h4-8,11,13-14,18,25H,9-10,12H2,1-3H3,(H,28,29)/t13-,14-,20-,21-/m1/s1 IMBIYJRGLQMLSC-VMHCRYLRSA-N 50341815 (1S,2R,3R)-1-[(R)-4-(5-Difluoromethylisoxazol-3-yl)-3-methylpiperazine--sulfonylamino]-2,3-dimethyl-2-phenylcyclopropanecarboxylicAcid::CHEMBL1767017 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm101609j 10.7270/Q2N87B3D 21417219 Shiozaki, M; Maeda, K; Miura, T; Kotoku, M; Yamasaki, T; Matsuda, I; Aoki, K; Yasue, K; Imai, H; Ubukata, M; Suma, A; Yokota, M; Hotta, T; Tanaka, M; Hase, Y; Haas, J; Fryer, AM; Laird, ER; Littmann, NM; Andrews, SW; Josey, JA; Mimura, T; Shinozaki, Y; Yoshiuchi, H; Inaba, T Central Pharmaceutical Research Institute http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50341815 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50341815&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 52952602 131344751 CHEMBL1767017 ZINC71315850 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50665829 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cn2c(nc3ccccc23)C(F)(F)F)cc1 InChI=1S/C22H21F3N4O4/c23-22(24,25)21-27-17-3-1-2-4-18(17)29(21)11-13-5-7-14(8-6-13)19(30)26-16-9-10-33-12-15(16)20(31)28-32/h1-8,15-16,32H,9-12H2,(H,26,30)(H,28,31)/t15-,16+/m0/s1 PGVYYPZKXKGBLD-JKSUJKDBSA-N 26806 (3R,4R)-3-N-hydroxy-4-N-(4-{[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]methyl}benzene)oxane-3,4-diamido::CHEMBL253275::benzimidazole analog., 32 Disintegrin and metalloproteinase domain-containing protein 17 130 ChEMBL 10.1016/j.ejmech.2011.09.018 10.7270/Q2JQ11FF 21963348 Sengupta, P; Puri, CS; Chokshi, HA; Sheth, CK; Midha, AS; Chitturi, TR; Thennati, R; Murumkar, PR; Yadav, MR Sun Pharma Advanced Research Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26806&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11294179 57298518 CHEMBL253275 ZINC13982474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50665830 Cc1nc2ccccc2n1Cc1ccc(cn1)C(=O)N[C@@H]1CCOC[C@@H]1C(=O)NO InChI=1S/C21H23N5O4/c1-13-23-18-4-2-3-5-19(18)26(13)11-15-7-6-14(10-22-15)20(27)24-17-8-9-30-12-16(17)21(28)25-29/h2-7,10,16-17,29H,8-9,11-12H2,1H3,(H,24,27)(H,25,28)/t16-,17+/m0/s1 DASDTNQBONOUKS-DLBZAZTESA-N 50355458 CHEMBL1835555 Disintegrin and metalloproteinase domain-containing protein 17 80 ChEMBL 10.1016/j.ejmech.2011.09.018 10.7270/Q2JQ11FF 21963348 Sengupta, P; Puri, CS; Chokshi, HA; Sheth, CK; Midha, AS; Chitturi, TR; Thennati, R; Murumkar, PR; Yadav, MR Sun Pharma Advanced Research Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355458 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355458&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56665352 136362144 CHEMBL1835555 ZINC72127898 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50665831 ONC(=O)[C@H]1COCC[C@H]1NC(=O)c1ccc(Cn2c(nc3ccccc23)C(F)(F)F)nc1 InChI=1S/C21H20F3N5O4/c22-21(23,24)20-27-16-3-1-2-4-17(16)29(20)10-13-6-5-12(9-25-13)18(30)26-15-7-8-33-11-14(15)19(31)28-32/h1-6,9,14-15,32H,7-8,10-11H2,(H,26,30)(H,28,31)/t14-,15+/m0/s1 GOTHOSMNYBPXSQ-LSDHHAIUSA-N 50355459 CHEMBL1835556 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1016/j.ejmech.2011.09.018 10.7270/Q2JQ11FF 21963348 Sengupta, P; Puri, CS; Chokshi, HA; Sheth, CK; Midha, AS; Chitturi, TR; Thennati, R; Murumkar, PR; Yadav, MR Sun Pharma Advanced Research Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355459 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355459&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56678961 136362145 CHEMBL1835556 ZINC72127899 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50665832 Cc1nc2ccccc2n1Cc1ccc(cn1)C(=O)N[C@@H]1CCCC[C@@H]1C(=O)NO InChI=1S/C22H25N5O3/c1-14-24-19-8-4-5-9-20(19)27(14)13-16-11-10-15(12-23-16)21(28)25-18-7-3-2-6-17(18)22(29)26-30/h4-5,8-12,17-18,30H,2-3,6-7,13H2,1H3,(H,25,28)(H,26,29)/t17-,18+/m0/s1 LHYOTWUSFMELDU-ZWKOTPCHSA-N 50355460 CHEMBL1835557 Disintegrin and metalloproteinase domain-containing protein 17 126 ChEMBL 10.1016/j.ejmech.2011.09.018 10.7270/Q2JQ11FF 21963348 Sengupta, P; Puri, CS; Chokshi, HA; Sheth, CK; Midha, AS; Chitturi, TR; Thennati, R; Murumkar, PR; Yadav, MR Sun Pharma Advanced Research Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355460 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355460&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56678962 136362146 CHEMBL1835557 ZINC72128691 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50665833 ONC(=O)[C@H]1CCCC[C@H]1NC(=O)c1ccc(Cn2c(nc3ccccc23)C(F)(F)F)nc1 InChI=1S/C22H22F3N5O3/c23-22(24,25)21-28-17-7-3-4-8-18(17)30(21)12-14-10-9-13(11-26-14)19(31)27-16-6-2-1-5-15(16)20(32)29-33/h3-4,7-11,15-16,33H,1-2,5-6,12H2,(H,27,31)(H,29,32)/t15-,16+/m0/s1 FZWNXIRLUBTKJY-JKSUJKDBSA-N 50355461 CHEMBL1835558 Disintegrin and metalloproteinase domain-containing protein 17 280 ChEMBL 10.1016/j.ejmech.2011.09.018 10.7270/Q2JQ11FF 21963348 Sengupta, P; Puri, CS; Chokshi, HA; Sheth, CK; Midha, AS; Chitturi, TR; Thennati, R; Murumkar, PR; Yadav, MR Sun Pharma Advanced Research Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355461 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355461&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56661881 136362147 CHEMBL1835558 ZINC72127911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50665834 Cc1nc2ccccc2n1Cc1ccc(cn1)C(=O)N[C@@H]1CCC[C@@H]1C(=O)NO InChI=1S/C21H23N5O3/c1-13-23-18-6-2-3-8-19(18)26(13)12-15-10-9-14(11-22-15)20(27)24-17-7-4-5-16(17)21(28)25-29/h2-3,6,8-11,16-17,29H,4-5,7,12H2,1H3,(H,24,27)(H,25,28)/t16-,17+/m0/s1 JKXLDQBQCXALPZ-DLBZAZTESA-N 50355462 CHEMBL1835559 Disintegrin and metalloproteinase domain-containing protein 17 70 ChEMBL 10.1016/j.ejmech.2011.09.018 10.7270/Q2JQ11FF 21963348 Sengupta, P; Puri, CS; Chokshi, HA; Sheth, CK; Midha, AS; Chitturi, TR; Thennati, R; Murumkar, PR; Yadav, MR Sun Pharma Advanced Research Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355462 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355462&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56678963 136362148 CHEMBL1835559 ZINC72142879 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50665835 ONC(=O)[C@H]1CCC[C@H]1NC(=O)c1ccc(Cn2c(nc3ccccc23)C(F)(F)F)nc1 InChI=1S/C21H20F3N5O3/c22-21(23,24)20-27-16-5-1-2-7-17(16)29(20)11-13-9-8-12(10-25-13)18(30)26-15-6-3-4-14(15)19(31)28-32/h1-2,5,7-10,14-15,32H,3-4,6,11H2,(H,26,30)(H,28,31)/t14-,15+/m0/s1 AHNMTSUUYUMNIJ-LSDHHAIUSA-N 50355463 CHEMBL1835560 Disintegrin and metalloproteinase domain-containing protein 17 74 ChEMBL 10.1016/j.ejmech.2011.09.018 10.7270/Q2JQ11FF 21963348 Sengupta, P; Puri, CS; Chokshi, HA; Sheth, CK; Midha, AS; Chitturi, TR; Thennati, R; Murumkar, PR; Yadav, MR Sun Pharma Advanced Research Company Ltd http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355463&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56678964 136362149 CHEMBL1835560 ZINC72127875 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50711769 COc1ccc(cc1)S(=O)(=O)N1CC(=O)N(O)C(=O)[C@H]1C(C)C InChI=1S/C14H18N2O6S/c1-9(2)13-14(18)16(19)12(17)8-15(13)23(20,21)11-6-4-10(22-3)5-7-11/h4-7,9,13,19H,8H2,1-3H3/t13-/m1/s1 FTRCUXMVUJZMHT-CYBMUJFWSA-N 50361599 CHEMBL1939844 Disintegrin and metalloproteinase domain-containing protein 17 33000 ChEMBL 10.1021/jm200593b 10.7270/Q2MP53QN 22017477 Marques, SM; Tuccinardi, T; Nuti, E; Santamaria, S; Andre, V; Rossello, A; Martinelli, A; Santos, MA Instituto Superior T£cnico http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361599 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361599&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56835169 136965661 CHEMBL1939844 ZINC73157513 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50711770 CC(C)[C@H]1N(CC(=O)N(O)C1=O)S(=O)(=O)c1ccc(cc1)-c1ccccc1 InChI=1S/C19H20N2O5S/c1-13(2)18-19(23)21(24)17(22)12-20(18)27(25,26)16-10-8-15(9-11-16)14-6-4-3-5-7-14/h3-11,13,18,24H,12H2,1-2H3/t18-/m1/s1 JVBFGGAYMSJQBZ-GOSISDBHSA-N 50361600 CHEMBL1939845 Disintegrin and metalloproteinase domain-containing protein 17 16000 ChEMBL 10.1021/jm200593b 10.7270/Q2MP53QN 22017477 Marques, SM; Tuccinardi, T; Nuti, E; Santamaria, S; Andre, V; Rossello, A; Martinelli, A; Santos, MA Instituto Superior T£cnico http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361600&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56835168 136965662 CHEMBL1939845 ZINC73165037 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50711771 CC(C)[C@H]1N(CC(=O)N(O)C1=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C19H20N2O6S/c1-13(2)18-19(23)21(24)17(22)12-20(18)28(25,26)16-10-8-15(9-11-16)27-14-6-4-3-5-7-14/h3-11,13,18,24H,12H2,1-2H3/t18-/m1/s1 RQCBSNJRFVZHOS-GOSISDBHSA-N 50361601 CHEMBL1939846 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/jm200593b 10.7270/Q2MP53QN 22017477 Marques, SM; Tuccinardi, T; Nuti, E; Santamaria, S; Andre, V; Rossello, A; Martinelli, A; Santos, MA Instituto Superior T£cnico http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361601&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 56835167 136965663 CHEMBL1939846 ZINC73221760 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50711772 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1021/jm200593b 10.7270/Q2MP53QN 22017477 Marques, SM; Tuccinardi, T; Nuti, E; Santamaria, S; Andre, V; Rossello, A; Martinelli, A; Santos, MA Instituto Superior T£cnico http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733265 Cc1cc(C)c(N(Cc2ccccc2)S(=O)(=O)c2ccc(OCc3ccccc3)cc2)c(c1)C(=O)NO InChI=1S/C29H28N2O5S/c1-21-17-22(2)28(27(18-21)29(32)30-33)31(19-23-9-5-3-6-10-23)37(34,35)26-15-13-25(14-16-26)36-20-24-11-7-4-8-12-24/h3-18,33H,19-20H2,1-2H3,(H,30,32) LSGQQGGAWBOKIB-UHFFFAOYSA-N 50103155 2-[Benzyl-(4-benzyloxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide::CHEMBL70207 Disintegrin and metalloproteinase domain-containing protein 17 429 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103155 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103155&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310756 103999499 CHEMBL70207 ZINC26273146 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733266 CCOc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(C)cc(C)cc1C(=O)NO InChI=1S/C24H26N2O5S/c1-4-31-20-10-12-21(13-11-20)32(29,30)26(16-19-8-6-5-7-9-19)23-18(3)14-17(2)15-22(23)24(27)25-28/h5-15,28H,4,16H2,1-3H3,(H,25,27) RGJXGQMBVWRXCQ-UHFFFAOYSA-N 50103153 2-[Benzyl-(4-ethoxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide::CHEMBL70957 Disintegrin and metalloproteinase domain-containing protein 17 173 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103153 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103153&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310757 103999497 CHEMBL70957 ZINC26290446 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733271 Cc1cc(C)c(N(Cc2ccccc2)S(=O)(=O)c2ccc(OCCc3ccccc3)cc2)c(c1)C(=O)NO InChI=1S/C30H30N2O5S/c1-22-19-23(2)29(28(20-22)30(33)31-34)32(21-25-11-7-4-8-12-25)38(35,36)27-15-13-26(14-16-27)37-18-17-24-9-5-3-6-10-24/h3-16,19-20,34H,17-18,21H2,1-2H3,(H,31,33) QVIMBPCQZGHONM-UHFFFAOYSA-N 50103157 2-[Benzyl-(4-phenethyloxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide::CHEMBL71007 Disintegrin and metalloproteinase domain-containing protein 17 467 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103157 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103157&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 22338710 103999501 CHEMBL71007 ZINC26291266 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733284 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2cccnc2)cc1 InChI=1S/C27H24BrN3O5S/c1-18-14-22(28)15-25(27(32)30-33)26(18)31(2)37(34,35)24-11-7-21(8-12-24)20-5-9-23(10-6-20)36-17-19-4-3-13-29-16-19/h3-16,33H,17H2,1-2H3,(H,30,32) AQCACFZZOGNMPR-UHFFFAOYSA-N 50103166 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(pyridin-3-ylmethoxy)-biphenyl-4-sulfonyl]-amino}-benzamide::CHEMBL305499 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103166 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103166&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309577 103999510 CHEMBL305499 ZINC26269643 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733286 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccccc2)cc1 InChI=1S/C28H25BrN2O5S/c1-19-16-23(29)17-26(28(32)30-33)27(19)31(2)37(34,35)25-14-10-22(11-15-25)21-8-12-24(13-9-21)36-18-20-6-4-3-5-7-20/h3-17,33H,18H2,1-2H3,(H,30,32) FJRQWHSKVHCEKG-UHFFFAOYSA-N 50103167 2-[(4'-Benzyloxy-biphenyl-4-sulfonyl)-methyl-amino]-5-bromo-N-hydroxy-3-methyl-benzamide::CHEMBL67590 Disintegrin and metalloproteinase domain-containing protein 17 57 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103167 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103167&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309533 103999511 CHEMBL67590 ZINC26276192 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733288 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)N(C)C InChI=1S/C23H26N4O5S/c1-16-12-18(26(2)3)13-21(23(28)25-29)22(16)27(15-17-6-5-11-24-14-17)33(30,31)20-9-7-19(32-4)8-10-20/h5-14,29H,15H2,1-4H3,(H,25,28) WYWAKLNLTJVWAB-UHFFFAOYSA-N 50103159 5-Dimethylamino-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::CHEMBL419995 Disintegrin and metalloproteinase domain-containing protein 17 633 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103159 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103159&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309879 103999503 CHEMBL419995 ZINC26278115 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733290 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2nccs2)cc1 InChI=1S/C25H22BrN3O5S2/c1-16-13-19(26)14-22(25(30)28-31)24(16)29(2)36(32,33)21-9-5-18(6-10-21)17-3-7-20(8-4-17)34-15-23-27-11-12-35-23/h3-14,31H,15H2,1-2H3,(H,28,30) PYSVMZGECWVLOT-UHFFFAOYSA-N 50103163 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiazol-2-ylmethoxy)-biphenyl-4-sulfonyl]-amino}-benzamide::CHEMBL71227 Disintegrin and metalloproteinase domain-containing protein 17 23 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103163 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103163&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309863 103999507 CHEMBL71227 ZINC26288691 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733296 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 231 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733301 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C21H20BrN3O5S/c1-14-10-16(22)11-19(21(26)24-27)20(14)25(13-15-4-3-9-23-12-15)31(28,29)18-7-5-17(30-2)6-8-18/h3-12,27H,13H2,1-2H3,(H,24,26) CZYVJSTWDMVAFM-UHFFFAOYSA-N 50103160 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::CHEMBL71725 Disintegrin and metalloproteinase domain-containing protein 17 43 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103160 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103160&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9914147 103999504 CHEMBL71725 ZINC26285988 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733304 CCCCOc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(C)cc(C)cc1C(=O)NO InChI=1S/C26H30N2O5S/c1-4-5-15-33-22-11-13-23(14-12-22)34(31,32)28(18-21-9-7-6-8-10-21)25-20(3)16-19(2)17-24(25)26(29)27-30/h6-14,16-17,30H,4-5,15,18H2,1-3H3,(H,27,29) VZKDMHBTNFCZIW-UHFFFAOYSA-N 50103173 2-[Benzyl-(4-butoxy-benzenesulfonyl)-amino]-N-hydroxy-3,5-dimethyl-benzamide::CHEMBL307990 Disintegrin and metalloproteinase domain-containing protein 17 377 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103173 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103173&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310984 103999517 CHEMBL307990 ZINC26290438 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733306 CN(c1c(C)cc(C)cc1C(=O)NO)S(=O)(=O)c1ccc(Sc2ccccc2)cc1 InChI=1S/C22H22N2O4S2/c1-15-13-16(2)21(20(14-15)22(25)23-26)24(3)30(27,28)19-11-9-18(10-12-19)29-17-7-5-4-6-8-17/h4-14,26H,1-3H3,(H,23,25) RRSNDPJAXNKWJB-UHFFFAOYSA-N 50103168 CHEMBL71686::N-Hydroxy-3,5-dimethyl-2-[methyl-(4-phenylsulfanyl-benzenesulfonyl)-amino]-benzamide Disintegrin and metalloproteinase domain-containing protein 17 727 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103168 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103168&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309550 103999512 CHEMBL71686 ZINC26281525 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733308 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1ccc2ccccc2c1 InChI=1S/C31H27N3O5S/c1-21-16-26(25-10-9-23-7-3-4-8-24(23)17-25)18-29(31(35)33-36)30(21)34(20-22-6-5-15-32-19-22)40(37,38)28-13-11-27(39-2)12-14-28/h3-19,36H,20H2,1-2H3,(H,33,35) PCSKPZLQCNGMCY-UHFFFAOYSA-N 50103162 CHEMBL68542::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-5-naphthalen-2-yl-benzamide Disintegrin and metalloproteinase domain-containing protein 17 194 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103162 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103162&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309329 103999506 CHEMBL68542 ZINC01494170 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733320 Cc1cc(Br)cc(C(=O)NO)c1N(Cc1ccccc1)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccccc2)cc1 InChI=1S/C34H29BrN2O5S/c1-24-20-29(35)21-32(34(38)36-39)33(24)37(22-25-8-4-2-5-9-25)43(40,41)31-18-14-28(15-19-31)27-12-16-30(17-13-27)42-23-26-10-6-3-7-11-26/h2-21,39H,22-23H2,1H3,(H,36,38) ZDRROEWAOPXRJQ-UHFFFAOYSA-N 50103170 2-[(4-Benzo[1,3]dioxol-5-yl-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL69569 Disintegrin and metalloproteinase domain-containing protein 17 285 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103170 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103170&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309482 103999514 CHEMBL69569 ZINC26268687 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733325 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cccc1C(=O)NO InChI=1S/C21H21N3O5S/c1-15-5-3-7-19(21(25)23-26)20(15)24(14-16-6-4-12-22-13-16)30(27,28)18-10-8-17(29-2)9-11-18/h3-13,26H,14H2,1-2H3,(H,23,25) AINJYWXKBKRQSX-UHFFFAOYSA-N 50096463 CHEMBL70176::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-benzamide::N-hydroxy-2-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-3-methylbenzamide Disintegrin and metalloproteinase domain-containing protein 17 231 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096463 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096463&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search WAY 1FM1,1FLS 4368 103993979 CHEMBL70176 DB02071 ZINC00602968 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733330 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1ccccc1 InChI=1S/C27H25N3O5S/c1-19-15-22(21-8-4-3-5-9-21)16-25(27(31)29-32)26(19)30(18-20-7-6-14-28-17-20)36(33,34)24-12-10-23(35-2)11-13-24/h3-17,32H,18H2,1-2H3,(H,29,31) MWNWUYJAANVQLN-UHFFFAOYSA-N 50103169 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL303666 Disintegrin and metalloproteinase domain-containing protein 17 64 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103169 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103169&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309437 103999513 CHEMBL303666 ZINC01494169 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733332 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccccc1)C(=O)NO InChI=1S/C27H25N3O5S/c1-19-15-24(21-8-4-3-5-9-21)26(25(16-19)27(31)29-32)30(18-20-7-6-14-28-17-20)36(33,34)23-12-10-22(35-2)11-13-23/h3-17,32H,18H2,1-2H3,(H,29,31) MQDWBVIPJPRWIJ-UHFFFAOYSA-N 50103164 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL68271 Disintegrin and metalloproteinase domain-containing protein 17 133 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103164 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103164&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309662 103999508 CHEMBL68271 ZINC26277793 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733338 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(cc1C(=O)NO)-c1cccc(c1)C(F)(F)F InChI=1S/C28H24F3N3O5S/c1-18-13-21(20-6-3-7-22(14-20)28(29,30)31)15-25(27(35)33-36)26(18)34(17-19-5-4-12-32-16-19)40(37,38)24-10-8-23(39-2)9-11-24/h3-16,36H,17H2,1-2H3,(H,33,35) RMZUAMXVNUZHBB-UHFFFAOYSA-N 50103171 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-3'-trifluoromethyl-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL304730 Disintegrin and metalloproteinase domain-containing protein 17 294 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103171 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103171&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309330 103999515 CHEMBL304730 ZINC26270973 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733343 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(C)cc(C)cc1C(=O)NO InChI=1S/C22H23N3O5S/c1-15-11-16(2)21(20(12-15)22(26)24-27)25(14-17-5-4-10-23-13-17)31(28,29)19-8-6-18(30-3)7-9-19/h4-13,27H,14H2,1-3H3,(H,24,26) CBLOGBROLDHLEE-UHFFFAOYSA-N 50103177 CHEMBL307079::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethyl-benzamide Disintegrin and metalloproteinase domain-containing protein 17 70 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103177 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103177&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310829 103999521 CHEMBL307079 ZINC26284152 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733346 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cc(C)cc1-c1ccco1)C(=O)NO InChI=1S/C25H23N3O6S/c1-17-13-21(23-6-4-12-34-23)24(22(14-17)25(29)27-30)28(16-18-5-3-11-26-15-18)35(31,32)20-9-7-19(33-2)8-10-20/h3-15,30H,16H2,1-2H3,(H,27,29) CBKKHHSQVZVIBM-UHFFFAOYSA-N 50103161 3-Furan-2-yl-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-5-methyl-benzamide::CHEMBL69268 Disintegrin and metalloproteinase domain-containing protein 17 61 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103161 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103161&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310790 103999505 CHEMBL69268 ZINC26277777 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733349 CN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccc(OCc2ccsc2)cc1 InChI=1S/C26H23BrN2O5S2/c1-17-13-21(27)14-24(26(30)28-31)25(17)29(2)36(32,33)23-9-5-20(6-10-23)19-3-7-22(8-4-19)34-15-18-11-12-35-16-18/h3-14,16,31H,15H2,1-2H3,(H,28,30) MLRVULAXCZJAAN-UHFFFAOYSA-N 50103176 5-Bromo-N-hydroxy-3-methyl-2-{methyl-[4'-(thiophen-3-ylmethoxy)-biphenyl-4-sulfonyl]-amino}-benzamide::CHEMBL71436 Disintegrin and metalloproteinase domain-containing protein 17 56 ChEMBL 10.1016/s0960-894x(01)00419-x 10.7270/Q2154HK0 11514167 Levin, JI; Chen, J; Du, M; Hogan, M; Kincaid, S; Nelson, FC; Venkatesan, AM; Wehr, T; Zask, A; DiJoseph, J; Killar, LM; Skala, S; Sung, A; Sharr, M; Roth, C; Jin, G; Cowling, R; Mohler, KM; Black, RA; March, CJ; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50103176 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50103176&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44309901 103999520 CHEMBL71436 ZINC26282329 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733884 COC(=O)c1cccc(C(=O)NO)c1N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C22H21N3O7S/c1-31-16-8-10-17(11-9-16)33(29,30)25(14-15-5-4-12-23-13-15)20-18(21(26)24-28)6-3-7-19(20)22(27)32-2/h3-13,28H,14H2,1-2H3,(H,24,26) WUQMFARMJJXJMN-UHFFFAOYSA-N 50096468 CHEMBL76974::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-isophthalamic acid methyl ester::methyl 3-(hydroxycarbamoyl)-2-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)benzoate Disintegrin and metalloproteinase domain-containing protein 17 38 ChEMBL 10.1016/s0960-894x(00)00642-9 10.7270/Q2TH8N78 11206467 Levin, JI; Du, MT; DiJoseph, JF; Killar, LM; Sung, A; Walter, T; Sharr, MA; Roth, CE; Moy, FJ; Powers, R; Jin, G; Cowling, R; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096468 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096468&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44316157 103993984 CHEMBL76974 ZINC26403485 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733886 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OCC(=O)NO)cccc1C(=O)NO InChI=1S/C23H23N3O8S/c1-33-17-10-12-18(13-11-17)35(31,32)26(14-16-6-3-2-4-7-16)22-19(23(28)25-30)8-5-9-20(22)34-15-21(27)24-29/h2-13,29-30H,14-15H2,1H3,(H,24,27)(H,25,28) CBMKHOZXSARYNG-UHFFFAOYSA-N 50096472 2-(N-benzyl-4-methoxyphenylsulfonamido)-N-hydroxy-3-(2-(hydroxyamino)-2-oxoethoxy)benzamide::2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-3-hydroxycarbamoylmethoxy-benzamide::CHEMBL80272 Disintegrin and metalloproteinase domain-containing protein 17 81 ChEMBL 10.1016/s0960-894x(00)00642-9 10.7270/Q2TH8N78 11206467 Levin, JI; Du, MT; DiJoseph, JF; Killar, LM; Sung, A; Walter, T; Sharr, MA; Roth, CE; Moy, FJ; Powers, R; Jin, G; Cowling, R; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096472 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096472&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44316333 103993988 CHEMBL80272 ZINC26472016 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50733935 COc1ccc(cc1)S(=O)(=O)N(Cc1ccccc1)c1c(OC)nc(OC)cc1C(=O)NO InChI=1S/C22H23N3O7S/c1-30-16-9-11-17(12-10-16)33(28,29)25(14-15-7-5-4-6-8-15)20-18(21(26)24-27)13-19(31-2)23-22(20)32-3/h4-13,27H,14H2,1-3H3,(H,24,26) XFKRGURHEZYQDK-UHFFFAOYSA-N 50096477 3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-2,6-dimethoxy-isonicotinamide::CHEMBL421699 Disintegrin and metalloproteinase domain-containing protein 17 294 ChEMBL 10.1016/s0960-894x(00)00644-2 10.7270/Q2PR7WHJ 11206468 Levin, JI; Gu, Y; Nelson, FC; Zask, A; DiJoseph, JF; Sharr, MA; Sung, A; Jin, G; Cowling, R; Chanda, P; Cosmi, S; Hsiao, CL; Edris, W; Wilhelm, J; Killar, LM; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50096477 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50096477&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9891009 103993993 CHEMBL421699 ZINC26475953 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50720543 C[C@@](CCc1ccc(cc1)-c1ccccc1)(C(=O)NO)S(C)(=O)=O InChI=1S/C18H21NO4S/c1-18(17(20)19-21,24(2,22)23)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)/t18-/m1/s1 GDYIQUFNICPYHF-GOSISDBHSA-N 50365344 CHEMBL1956115 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm2014748 10.7270/Q2VX0H0W 22175825 Brown, MF; Reilly, U; Abramite, JA; Arcari, JT; Oliver, R; Barham, RA; Che, Y; Chen, JM; Collantes, EM; Chung, SW; Desbonnet, C; Doty, J; Doroski, M; Engtrakul, JJ; Harris, TM; Huband, M; Knafels, JD; Leach, KL; Liu, S; Marfat, A; Marra, A; McElroy, E; Melnick, M; Menard, CA; Montgomery, JI; Mullins, L; Noe, MC; O'Donnell, J; Penzien, J; Plummer, MS; Price, LM; Shanmugasundaram, V; Thoma, C; Uccello, DP; Warmus, JS; Wishka, DG Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50365344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50365344&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 51355576 136969406 CHEMBL1956115 ZINC73311685 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734327 CCN(CC)CC#CCN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C23H28BrN3O5S/c1-5-26(6-2)13-7-8-14-27(33(30,31)20-11-9-19(32-4)10-12-20)22-17(3)15-18(24)16-21(22)23(28)25-29/h9-12,15-16,29H,5-6,13-14H2,1-4H3,(H,25,28) AWDZLFOJMUGNPS-UHFFFAOYSA-N 50106132 5-Bromo-2-[(4-diethylamino-but-2-ynyl)-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL100134 Disintegrin and metalloproteinase domain-containing protein 17 36 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106132&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44332313 104001712 CHEMBL100134 ZINC26816670 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734329 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 231 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734333 COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(CN(C)C)cc1)c1c(C)cccc1C(=O)NO InChI=1S/C25H29N3O5S/c1-18-6-5-7-23(25(29)26-30)24(18)28(17-20-10-8-19(9-11-20)16-27(2)3)34(31,32)22-14-12-21(33-4)13-15-22/h5-15,30H,16-17H2,1-4H3,(H,26,29) LYVGWVHFXOYMDJ-UHFFFAOYSA-N 50106138 2-[(4-Dimethylaminomethyl-benzyl)-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL100950 Disintegrin and metalloproteinase domain-containing protein 17 243 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106138 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106138&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310753 104001718 CHEMBL100950 ZINC26751530 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734335 CN(c1c(CN2CCN(C)CC2)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C26H28BrClN4O5S/c1-30-11-13-32(14-12-30)17-18-15-19(27)16-24(26(33)29-34)25(18)31(2)38(35,36)23-9-7-22(8-10-23)37-21-5-3-20(28)4-6-21/h3-10,15-16,34H,11-14,17H2,1-2H3,(H,29,33) LGVIBWRSRHZDQG-UHFFFAOYSA-N 50106133 5-Bromo-2-{[4-(4-chloro-phenoxy)-benzenesulfonyl]-methyl-amino}-N-hydroxy-3-(4-methyl-piperazin-1-ylmethyl)-benzamide::CHEMBL101612 Disintegrin and metalloproteinase domain-containing protein 17 80 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106133&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44332107 104001713 CHEMBL101612 ZINC26745756 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734338 CCN(CC)Cc1cccc(C(=O)NO)c1N(C)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C20H27N3O5S/c1-5-23(6-2)14-15-8-7-9-18(20(24)21-25)19(15)22(3)29(26,27)17-12-10-16(28-4)11-13-17/h7-13,25H,5-6,14H2,1-4H3,(H,21,24) CNEKWCSJAXATCC-UHFFFAOYSA-N 50106139 3-Diethylaminomethyl-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-benzamide::CHEMBL101981 Disintegrin and metalloproteinase domain-containing protein 17 210 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106139 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106139&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310789 104001719 CHEMBL101981 ZINC26744106 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734346 COc1ccc(cc1)S(=O)(=O)N(C)c1c(Cn2ccnc2)cccc1C(=O)NO InChI=1S/C19H20N4O5S/c1-22(29(26,27)16-8-6-15(28-2)7-9-16)18-14(12-23-11-10-20-13-23)4-3-5-17(18)19(24)21-25/h3-11,13,25H,12H2,1-2H3,(H,21,24) AJXYMDJBIXFLCO-UHFFFAOYSA-N 50106134 CHEMBL101413::N-Hydroxy-3-imidazol-1-ylmethyl-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-benzamide Disintegrin and metalloproteinase domain-containing protein 17 157 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106134 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106134&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310851 104001714 CHEMBL101413 ZINC26748275 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734347 COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(cc1)N1CCN(C)CC1)c1c(C)cccc1C(=O)NO InChI=1S/C27H32N4O5S/c1-20-5-4-6-25(27(32)28-33)26(20)31(37(34,35)24-13-11-23(36-3)12-14-24)19-21-7-9-22(10-8-21)30-17-15-29(2)16-18-30/h4-14,33H,15-19H2,1-3H3,(H,28,32) SDPZKVFCJYXZLE-UHFFFAOYSA-N 50106142 CHEMBL318922::N-Hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(4-methyl-piperazin-1-yl)-benzyl]-amino}-3-methyl-benzamide Disintegrin and metalloproteinase domain-containing protein 17 146 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106142 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106142&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17866459 104001722 CHEMBL318922 ZINC26745086 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734352 COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(C)CC2)cc(cc1C(=O)NO)-c1ccc(OC(F)(F)F)cc1 InChI=1S/C28H31F3N4O6S/c1-33-12-14-35(15-13-33)18-21-16-20(19-4-6-23(7-5-19)41-28(29,30)31)17-25(27(36)32-37)26(21)34(2)42(38,39)24-10-8-22(40-3)9-11-24/h4-11,16-17,37H,12-15,18H2,1-3H3,(H,32,36) CLPQPSHMBDAYLR-UHFFFAOYSA-N 50106141 4-[(4-Methoxy-benzenesulfonyl)-methyl-amino]-5-(4-methyl-piperazin-1-ylmethyl)-4'-trifluoromethoxy-biphenyl-3-carboxylic acid hydroxyamide::CHEMBL102057 Disintegrin and metalloproteinase domain-containing protein 17 210 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106141 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106141&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44331984 104001721 CHEMBL102057 ZINC26745233 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734355 COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(C)CC2)cccc1C(=O)NO InChI=1S/C21H28N4O5S/c1-23-11-13-25(14-12-23)15-16-5-4-6-19(21(26)22-27)20(16)24(2)31(28,29)18-9-7-17(30-3)8-10-18/h4-10,27H,11-15H2,1-3H3,(H,22,26) YIIGCCOQJNYBNF-UHFFFAOYSA-N 50106130 CHEMBL100512::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-(4-methyl-piperazin-1-ylmethyl)-benzamide Disintegrin and metalloproteinase domain-containing protein 17 154 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106130&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17866675 104001710 CHEMBL100512 ZINC26744958 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734358 COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(OCCN2CCCCC2)cc1)c1c(C)cccc1C(=O)NO InChI=1S/C29H35N3O6S/c1-22-7-6-8-27(29(33)30-34)28(22)32(39(35,36)26-15-13-24(37-2)14-16-26)21-23-9-11-25(12-10-23)38-20-19-31-17-4-3-5-18-31/h6-16,34H,3-5,17-21H2,1-2H3,(H,30,33) QDBZCMIHMMMYES-UHFFFAOYSA-N 50106128 CHEMBL100081::N-Hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-amino}-3-methyl-benzamide Disintegrin and metalloproteinase domain-containing protein 17 277 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106128&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15551877 104001708 CHEMBL100081 ZINC26752239 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734360 COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(CC2)C(=O)OC(C)(C)C)cc(Br)cc1C(=O)NO InChI=1S/C25H33BrN4O7S/c1-25(2,3)37-24(32)30-12-10-29(11-13-30)16-17-14-18(26)15-21(23(31)27-33)22(17)28(4)38(34,35)20-8-6-19(36-5)7-9-20/h6-9,14-15,33H,10-13,16H2,1-5H3,(H,27,31) FMQWWPFJFLUCHZ-UHFFFAOYSA-N 50106140 4-{5-Bromo-3-hydroxycarbamoyl-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-benzyl}-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL101210 Disintegrin and metalloproteinase domain-containing protein 17 63 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106140 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106140&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44332161 104001720 CHEMBL101210 ZINC26745731 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734361 COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(CC2)c2ccccc2)cc(Br)cc1C(=O)NO InChI=1S/C26H29BrN4O5S/c1-29(37(34,35)23-10-8-22(36-2)9-11-23)25-19(16-20(27)17-24(25)26(32)28-33)18-30-12-14-31(15-13-30)21-6-4-3-5-7-21/h3-11,16-17,33H,12-15,18H2,1-2H3,(H,28,32) JIYWMQDJGOAJMD-UHFFFAOYSA-N 50106144 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-(4-phenyl-piperazin-1-ylmethyl)-benzamide::CHEMBL319902 Disintegrin and metalloproteinase domain-containing protein 17 87 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106144 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106144&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44331932 104001724 CHEMBL319902 ZINC26817146 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734363 COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCOCC2)cccc1C(=O)NO InChI=1S/C20H25N3O6S/c1-22(30(26,27)17-8-6-16(28-2)7-9-17)19-15(14-23-10-12-29-13-11-23)4-3-5-18(19)20(24)21-25/h3-9,25H,10-14H2,1-2H3,(H,21,24) WGMQZHYPIKBUML-UHFFFAOYSA-N 50106137 CHEMBL100280::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-morpholin-4-ylmethyl-benzamide Disintegrin and metalloproteinase domain-containing protein 17 174 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106137 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106137&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310824 104001717 CHEMBL100280 ZINC26750413 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734382 COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(C)CC2)cc(Br)cc1C(=O)NO InChI=1S/C21H27BrN4O5S/c1-24-8-10-26(11-9-24)14-15-12-16(22)13-19(21(27)23-28)20(15)25(2)32(29,30)18-6-4-17(31-3)5-7-18/h4-7,12-13,28H,8-11,14H2,1-3H3,(H,23,27) DPCXVXNEMYTZOE-UHFFFAOYSA-N 50106147 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-(4-methyl-piperazin-1-ylmethyl)-benzamide::CHEMBL101864 Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106147 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106147&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9936712 104001727 CHEMBL101864 ZINC26747346 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734387 COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(OCCN2CCCCC2)cc1)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C29H34BrN3O6S/c1-21-18-23(30)19-27(29(34)31-35)28(21)33(40(36,37)26-12-10-24(38-2)11-13-26)20-22-6-8-25(9-7-22)39-17-16-32-14-4-3-5-15-32/h6-13,18-19,35H,3-5,14-17,20H2,1-2H3,(H,31,34) KSLUOGMHCJCRLQ-UHFFFAOYSA-N 50106145 5-Bromo-N-hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-amino}-3-methyl-benzamide::CHEMBL99745 Disintegrin and metalloproteinase domain-containing protein 17 108 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106145 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106145&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17866387 104001725 CHEMBL99745 ZINC26750874 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734391 COc1ccc(cc1)S(=O)(=O)N(C)c1c(CN2CCN(C)CC2)cc(cc1C(=O)NO)-c1ccc2ccccc2c1 InChI=1S/C31H34N4O5S/c1-33-14-16-35(17-15-33)21-26-19-25(24-9-8-22-6-4-5-7-23(22)18-24)20-29(31(36)32-37)30(26)34(2)41(38,39)28-12-10-27(40-3)11-13-28/h4-13,18-20,37H,14-17,21H2,1-3H3,(H,32,36) QAFRSDWNZLQCBN-UHFFFAOYSA-N 50106131 CHEMBL100777::N-Hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-(4-methyl-piperazin-1-ylmethyl)-5-naphthalen-2-yl-benzamide Disintegrin and metalloproteinase domain-containing protein 17 49 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106131&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44331983 104001711 CHEMBL100777 ZINC26745223 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734393 CCN(CC)CC#CCN(c1c(C)cccc1C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C23H29N3O5S/c1-5-25(6-2)16-7-8-17-26(22-18(3)10-9-11-21(22)23(27)24-28)32(29,30)20-14-12-19(31-4)13-15-20/h9-15,28H,5-6,16-17H2,1-4H3,(H,24,27) IPNPHTJFPPPVQA-UHFFFAOYSA-N 50106146 2-[(4-Diethylamino-but-2-ynyl)-(4-methoxy-benzenesulfonyl)-amino]-N-hydroxy-3-methyl-benzamide::CHEMBL320383 Disintegrin and metalloproteinase domain-containing protein 17 218 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106146 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106146&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 21310751 104001726 CHEMBL320383 ZINC26744615 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734401 COC(=O)C1CCCN1Cc1cccc(C(=O)NO)c1N(C)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C22H27N3O7S/c1-24(33(29,30)17-11-9-16(31-2)10-12-17)20-15(6-4-7-18(20)21(26)23-28)14-25-13-5-8-19(25)22(27)32-3/h4,6-7,9-12,19,28H,5,8,13-14H2,1-3H3,(H,23,26) CFEKPCYWRLBSBI-UHFFFAOYSA-N 50106143 1-{3-Hydroxycarbamoyl-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-benzyl}-pyrrolidine-2-carboxylic acid methyl ester::CHEMBL100564 Disintegrin and metalloproteinase domain-containing protein 17 200 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106143 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106143&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44332003 104001723 CHEMBL100564 ZINC26744967 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734411 COc1ccc(cc1)S(=O)(=O)N(CC#CCN1CCN(C)CC1)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C24H29BrN4O5S/c1-18-16-19(25)17-22(24(30)26-31)23(18)29(11-5-4-10-28-14-12-27(2)13-15-28)35(32,33)21-8-6-20(34-3)7-9-21/h6-9,16-17,31H,10-15H2,1-3H3,(H,26,30) HEYGZWVOCCBCPY-UHFFFAOYSA-N 50106129 5-Bromo-N-hydroxy-2-{(4-methoxy-benzenesulfonyl)-[4-(4-methyl-piperazin-1-yl)-but-2-ynyl]-amino}-3-methyl-benzamide::CHEMBL319887 Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106129&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44331976 104001709 CHEMBL319887 ZINC26744110 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50734412 CN(c1c(CN2CCN(C)CC2)cccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C26H29ClN4O5S/c1-29-14-16-31(17-15-29)18-19-4-3-5-24(26(32)28-33)25(19)30(2)37(34,35)23-12-10-22(11-13-23)36-21-8-6-20(27)7-9-21/h3-13,33H,14-18H2,1-2H3,(H,28,32) YYZDREAOBMTNAP-UHFFFAOYSA-N 50106136 2-{[4-(4-Chloro-phenoxy)-benzenesulfonyl]-methyl-amino}-N-hydroxy-3-(4-methyl-piperazin-1-ylmethyl)-benzamide::CHEMBL319341 Disintegrin and metalloproteinase domain-containing protein 17 122 ChEMBL 10.1016/s0960-894x(01)00601-1 10.7270/Q2125T64 11677139 Levin, JI; Chen, JM; Du, MT; Nelson, FC; Wehr, T; DiJoseph, JF; Killar, LM; Skala, S; Sung, A; Sharr, MA; Roth, CE; Jin, G; Cowling, R; Di, L; Sherman, M; Xu, ZB; March, CJ; Mohler, KM; Black, RA; Skotnicki, JS Wyeth-Ayerst Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106136 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106136&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10076090 104001716 CHEMBL319341 ZINC22450147 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50584820 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2cccc(F)c2)cc1 InChI=1S/C19H21FN2O6S/c20-14-3-1-2-13(10-14)12-28-16-4-6-17(7-5-16)29(26,27)22-9-8-15(23)11-18(22)19(24)21-25/h1-7,10,15,18,23,25H,8-9,11-12H2,(H,21,24)/t15-,18+/m0/s1 GPJUMXDCOLWYIL-MAUKXSAKSA-N 50113043 (2R,4S)-1-[4-(3-Fluoro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28299 Disintegrin and metalloproteinase domain-containing protein 17 9000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113043 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113043&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278424 104007394 CHEMBL28299 ZINC13441609 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809739 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(Oc2ccc(N)cc2)cc1 InChI=1S/C24H26N3O5P/c1-2-31-33(30,22-13-11-21(12-14-22)32-20-9-7-19(25)8-10-20)27-16-18-6-4-3-5-17(18)15-23(27)24(28)26-29/h3-14,23,29H,2,15-16,25H2,1H3,(H,26,28) BJNHISLNENZLDD-UHFFFAOYSA-N 50109621 CHEMBL425316::[4-(4-Amino-phenoxy)-phenyl]-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester Disintegrin and metalloproteinase domain-containing protein 17 21.7 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109621 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109621&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383786 104004561 CHEMBL425316 ZINC28009001 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809745 CCOP(=O)(N1Cc2[nH]c3ccccc3c2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C21H24N3O5P/c1-3-29-30(27,15-10-8-14(28-2)9-11-15)24-13-19-17(12-20(24)21(25)23-26)16-6-4-5-7-18(16)22-19/h4-11,20,22,26H,3,12-13H2,1-2H3,(H,23,25) OHBFRMUALPHZIT-UHFFFAOYSA-N 50109633 (3-Hydroxycarbamoyl-1,3,4,9-tetrahydro-beta-carbolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL172249 Disintegrin and metalloproteinase domain-containing protein 17 2.2 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109633 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109633&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384395 104004573 CHEMBL172249 ZINC28014430 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809755 COc1ccc(cc1)P(=O)(OCCc1ccc(cc1)-c1ccccc1)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C31H31N2O5P/c1-37-28-15-17-29(18-16-28)39(36,33-22-27-10-6-5-9-26(27)21-30(33)31(34)32-35)38-20-19-23-11-13-25(14-12-23)24-7-3-2-4-8-24/h2-18,30,35H,19-22H2,1H3,(H,32,34) PCAPSCAFNCUGDE-UHFFFAOYSA-N 50109617 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-biphenyl-4-yl-ethyl ester::CHEMBL173754 Disintegrin and metalloproteinase domain-containing protein 17 90.20 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109617&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383847 104004557 CHEMBL173754 ZINC28007074 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809763 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccncc1 InChI=1S/C17H20N3O4P/c1-2-24-25(23,15-7-9-18-10-8-15)20-12-14-6-4-3-5-13(14)11-16(20)17(21)19-22/h3-10,16,22H,2,11-12H2,1H3,(H,19,21) RLVHPDACJUGNSL-UHFFFAOYSA-N 50109638 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-pyridin-4-yl-phosphinic acid ethyl ester::CHEMBL171986 Disintegrin and metalloproteinase domain-containing protein 17 777 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109638 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109638&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384005 104004578 CHEMBL171986 ZINC27998008 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809765 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(Oc2ccccc2)cc1 InChI=1S/C24H25N2O5P/c1-2-30-32(29,22-14-12-21(13-15-22)31-20-10-4-3-5-11-20)26-17-19-9-7-6-8-18(19)16-23(26)24(27)25-28/h3-15,23,28H,2,16-17H2,1H3,(H,25,27) QSFJZGINKPYVRC-UHFFFAOYSA-N 50109635 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-phenoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL355797 Disintegrin and metalloproteinase domain-containing protein 17 7.89 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109635 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109635&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383747 104004575 CHEMBL355797 ZINC28012042 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809794 COc1ccc(cc1)P(=O)(OCC1CCCCC1)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C24H31N2O5P/c1-30-21-11-13-22(14-12-21)32(29,31-17-18-7-3-2-4-8-18)26-16-20-10-6-5-9-19(20)15-23(26)24(27)25-28/h5-6,9-14,18,23,28H,2-4,7-8,15-17H2,1H3,(H,25,27) KMYAHTGTYRRWEK-UHFFFAOYSA-N 50109622 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid cyclohexylmethyl ester::CHEMBL173846 Disintegrin and metalloproteinase domain-containing protein 17 15.5 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109622 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109622&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383849 104004562 CHEMBL173846 ZINC28007094 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809798 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(C)cc1 InChI=1S/C19H23N2O4P/c1-3-25-26(24,17-10-8-14(2)9-11-17)21-13-16-7-5-4-6-15(16)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22) USYXNFCQBGQYRW-UHFFFAOYSA-N 50109636 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-p-tolyl-phosphinic acid ethyl ester::CHEMBL172886 Disintegrin and metalloproteinase domain-containing protein 17 500 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109636 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109636&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384591 104004576 CHEMBL172886 ZINC28013135 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809801 COc1ccc(cc1)P(=O)(OCCc1ccccc1)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C25H27N2O5P/c1-31-22-11-13-23(14-12-22)33(30,32-16-15-19-7-3-2-4-8-19)27-18-21-10-6-5-9-20(21)17-24(27)25(28)26-29/h2-14,24,29H,15-18H2,1H3,(H,26,28) AIBDPCDNFOFGFS-UHFFFAOYSA-N 50109618 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid phenethyl ester::CHEMBL174315 Disintegrin and metalloproteinase domain-containing protein 17 42.2 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109618 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109618&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383801 104004558 CHEMBL174315 ZINC13472481 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812462 CCCCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C22H27ClN2O5S/c1-2-3-14-25-15-12-22(13-16-25,21(26)24-27)31(28,29)20-10-8-19(9-11-20)30-18-6-4-17(23)5-7-18/h4-11,27H,2-3,12-16H2,1H3,(H,24,26) DTPBPOWGEIFZGM-UHFFFAOYSA-N 50128668 1-Butyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide::1-butyl-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL311357 Disintegrin and metalloproteinase domain-containing protein 17 301 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128668 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128668&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9890733 104020431 CHEMBL311357 ZINC13521089 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812467 CCC(CC)Oc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccccc2)CC1)C(=O)NO InChI=1S/C24H32N2O5S/c1-3-20(4-2)31-21-10-12-22(13-11-21)32(29,30)24(23(27)25-28)14-16-26(17-15-24)18-19-8-6-5-7-9-19/h5-13,20,28H,3-4,14-18H2,1-2H3,(H,25,27) KHORRYDPPCADSY-UHFFFAOYSA-N 50128664 1-Benzyl-4-[4-(1-ethyl-propoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL80321 Disintegrin and metalloproteinase domain-containing protein 17 39 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128664 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128664&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44317086 104020427 CHEMBL80321 ZINC26472376 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812478 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(Cl)c(Cl)c2)CC1)C(=O)NO InChI=1S/C20H22Cl2N2O5S/c1-29-15-3-5-16(6-4-15)30(27,28)20(19(25)23-26)8-10-24(11-9-20)13-14-2-7-17(21)18(22)12-14/h2-7,12,26H,8-11,13H2,1H3,(H,23,25) NPFGSGCFKYSLPI-UHFFFAOYSA-N 50128672 1-(3,4-Dichloro-benzyl)-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-(3,4-dichlorobenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::CHEMBL78962 Disintegrin and metalloproteinase domain-containing protein 17 115 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128672 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128672&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9869441 104020435 CHEMBL78962 ZINC13520960 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812479 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(cc2)-c2ccccc2)CC1)C(=O)NO InChI=1S/C26H28N2O5S/c1-33-23-11-13-24(14-12-23)34(31,32)26(25(29)27-30)15-17-28(18-16-26)19-20-7-9-22(10-8-20)21-5-3-2-4-6-21/h2-14,30H,15-19H2,1H3,(H,27,29) UTDYWIPXAVCYCE-UHFFFAOYSA-N 50128650 1-Biphenyl-4-ylmethyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL76137 Disintegrin and metalloproteinase domain-containing protein 17 610 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128650 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128650&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9956833 104020413 CHEMBL76137 ZINC13520975 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812484 COc1ccc(cc1)S(=O)(=O)C1(CCN(CCOc2ccccc2)CC1)C(=O)NO InChI=1S/C21H26N2O6S/c1-28-17-7-9-19(10-8-17)30(26,27)21(20(24)22-25)11-13-23(14-12-21)15-16-29-18-5-3-2-4-6-18/h2-10,25H,11-16H2,1H3,(H,22,24) YJOSMOCGEMCNLK-UHFFFAOYSA-N 50128676 4-(4-Methoxy-benzenesulfonyl)-1-(2-phenoxy-ethyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL76847::N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(2-phenoxyethyl)piperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 293 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128676&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9954604 104020439 CHEMBL76847 ZINC13521056 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812487 CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C20H23ClN2O5S/c1-2-23-13-11-20(12-14-23,19(24)22-25)29(26,27)18-9-7-17(8-10-18)28-16-5-3-15(21)4-6-16/h3-10,25H,2,11-14H2,1H3,(H,22,24) AUWOIDNULNLPBA-UHFFFAOYSA-N 50128651 4-(4-(4-chlorophenoxy)phenylsulfonyl)-1-ethyl-N-hydroxypiperidine-4-carboxamide::4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL78549 Disintegrin and metalloproteinase domain-containing protein 17 413 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128651 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128651&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9803207 104020414 CHEMBL78549 ZINC13521084 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812494 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(OCCN3CCCCC3)cc2)CC1)C(=O)NO InChI=1S/C27H37N3O6S/c1-35-23-9-11-25(12-10-23)37(33,34)27(26(31)28-32)13-17-30(18-14-27)21-22-5-7-24(8-6-22)36-20-19-29-15-3-2-4-16-29/h5-12,32H,2-4,13-21H2,1H3,(H,28,31) PRBMKJZQAUSBQV-UHFFFAOYSA-N 50128670 1-(4-(2-(piperidin-1-yl)ethoxy)benzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-Methoxy-benzenesulfonyl)-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL76836 Disintegrin and metalloproteinase domain-containing protein 17 386 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128670 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128670&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9849957 104020433 CHEMBL76836 ZINC03820512 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812495 ONC(=O)C1(CCN(Cc2ccccc2)CC1)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C25H25ClN2O5S/c26-20-6-8-21(9-7-20)33-22-10-12-23(13-11-22)34(31,32)25(24(29)27-30)14-16-28(17-15-25)18-19-4-2-1-3-5-19/h1-13,30H,14-18H2,(H,27,29) IMKDKHQDFFLOKK-UHFFFAOYSA-N 50128648 1-Benzyl-4-[4-(4-chloro-phenoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL79433 Disintegrin and metalloproteinase domain-containing protein 17 301 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128648 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128648&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9957653 104020411 CHEMBL79433 ZINC03818184 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812503 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(OCCN3CCCCC3)cc2)CC1)C(=O)NO InChI=1S/C30H43N3O6S/c1-2-3-22-38-27-11-13-28(14-12-27)40(36,37)30(29(34)31-35)15-19-33(20-16-30)24-25-7-9-26(10-8-25)39-23-21-32-17-5-4-6-18-32/h7-14,35H,2-6,15-24H2,1H3,(H,31,34) GQEYBNSJJQDDLY-UHFFFAOYSA-N 50128645 1-(4-(2-(piperidin-1-yl)ethoxy)benzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-(4-Butoxy-benzenesulfonyl)-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL78798 Disintegrin and metalloproteinase domain-containing protein 17 581 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128645 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128645&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9851086 104020408 CHEMBL78798 ZINC26476514 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812507 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(CCOc2ccccc2)CC1)C(=O)NO InChI=1S/C24H32N2O6S/c1-2-3-18-31-21-9-11-22(12-10-21)33(29,30)24(23(27)25-28)13-15-26(16-14-24)17-19-32-20-7-5-4-6-8-20/h4-12,28H,2-3,13-19H2,1H3,(H,25,27) GMRJGTBNERTZIB-UHFFFAOYSA-N 50128671 4-(4-Butoxy-benzenesulfonyl)-1-(2-phenoxy-ethyl)-piperidine-4-carboxylic acid hydroxyamide::4-(4-butoxyphenylsulfonyl)-N-hydroxy-1-(2-phenoxyethyl)piperidine-4-carboxamide::CHEMBL306617 Disintegrin and metalloproteinase domain-containing protein 17 270 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128671 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128671&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9869598 104020434 CHEMBL306617 ZINC13521060 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812509 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(cc2)-c2ccccn2)CC1)C(=O)NO InChI=1S/C25H27N3O5S/c1-33-21-9-11-22(12-10-21)34(31,32)25(24(29)27-30)13-16-28(17-14-25)18-19-5-7-20(8-6-19)23-4-2-3-15-26-23/h2-12,15,30H,13-14,16-18H2,1H3,(H,27,29) UYOSMJLYSRXRLI-UHFFFAOYSA-N 50128641 1-(4-(pyridin-2-yl)benzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-Methoxy-benzenesulfonyl)-1-(4-pyridin-2-yl-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL80798 Disintegrin and metalloproteinase domain-containing protein 17 298 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128641 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128641&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10277568 104020404 CHEMBL80798 ZINC03820514 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812510 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc3ccccc3c2)CC1)C(=O)NO InChI=1S/C24H26N2O5S/c1-31-21-8-10-22(11-9-21)32(29,30)24(23(27)25-28)12-14-26(15-13-24)17-18-6-7-19-4-2-3-5-20(19)16-18/h2-11,16,28H,12-15,17H2,1H3,(H,25,27) GNNAXEPAOIUDTH-UHFFFAOYSA-N 50128663 4-(4-Methoxy-benzenesulfonyl)-1-naphthalen-2-ylmethyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL312429::N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(naphthalen-2-ylmethyl)piperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 170 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128663 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128663&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9868577 104020426 CHEMBL312429 ZINC13520969 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812514 CN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C19H21ClN2O5S/c1-22-12-10-19(11-13-22,18(23)21-24)28(25,26)17-8-6-16(7-9-17)27-15-4-2-14(20)3-5-15/h2-9,24H,10-13H2,1H3,(H,21,23) WUWBMHSDQYCLTI-UHFFFAOYSA-N 50128674 4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxy-1-methylpiperidine-4-carboxamide::4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-methyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL78337 Disintegrin and metalloproteinase domain-containing protein 17 270 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128674 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128674&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9932167 104020437 CHEMBL78337 ZINC13521080 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812516 COc1ccc(cc1)S(=O)(=O)C1(CCN(CCCc2ccccc2)CC1)C(=O)NO InChI=1S/C22H28N2O5S/c1-29-19-9-11-20(12-10-19)30(27,28)22(21(25)23-26)13-16-24(17-14-22)15-5-8-18-6-3-2-4-7-18/h2-4,6-7,9-12,26H,5,8,13-17H2,1H3,(H,23,25) FTWZRZIOCFAVKU-UHFFFAOYSA-N 50128660 4-(4-Methoxy-benzenesulfonyl)-1-(3-phenyl-propyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL312770::N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(3-phenylpropyl)piperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 503 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128660 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128660&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9954513 104020423 CHEMBL312770 ZINC13520987 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812517 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccccc2)CC1)C(=O)NO InChI=1S/C20H24N2O5S/c1-27-17-7-9-18(10-8-17)28(25,26)20(19(23)21-24)11-13-22(14-12-20)15-16-5-3-2-4-6-16/h2-10,24H,11-15H2,1H3,(H,21,23) NZSGHPOSLLMCJS-UHFFFAOYSA-N 50128652 1-Benzyl-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::CHEMBL80969 Disintegrin and metalloproteinase domain-containing protein 17 229 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128652 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128652&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9865936 104020415 CHEMBL80969 ZINC13520952 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812521 ONC(=O)C1(CCN(Cc2ccccc2)CC1)S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C26H28N2O5S/c29-25(27-30)26(15-17-28(18-16-26)19-21-7-3-1-4-8-21)34(31,32)24-13-11-23(12-14-24)33-20-22-9-5-2-6-10-22/h1-14,30H,15-20H2,(H,27,29) ATFPFLNWBZIBTJ-UHFFFAOYSA-N 50128654 1-Benzyl-4-(4-benzyloxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-Benzyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-4-(4-(benzyloxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL78369 Disintegrin and metalloproteinase domain-containing protein 17 416 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128654&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9913053 104020417 CHEMBL78369 ZINC13521077 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812524 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(C)CC1)C(=O)NO InChI=1S/C17H26N2O5S/c1-3-4-13-24-14-5-7-15(8-6-14)25(22,23)17(16(20)18-21)9-11-19(2)12-10-17/h5-8,21H,3-4,9-13H2,1-2H3,(H,18,20) NLPICQLAIKGJBE-UHFFFAOYSA-N 50128665 4-(4-Butoxy-benzenesulfonyl)-1-methyl-piperidine-4-carboxylic acid hydroxyamide::4-(4-butoxyphenylsulfonyl)-N-hydroxy-1-methylpiperidine-4-carboxamide::CHEMBL419648 Disintegrin and metalloproteinase domain-containing protein 17 594 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128665 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128665&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9820708 104020428 CHEMBL419648 ZINC13521064 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812532 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2cccc(OC)c2)CC1)C(=O)NO InChI=1S/C24H32N2O6S/c1-3-4-16-32-20-8-10-22(11-9-20)33(29,30)24(23(27)25-28)12-14-26(15-13-24)18-19-6-5-7-21(17-19)31-2/h5-11,17,28H,3-4,12-16,18H2,1-2H3,(H,25,27) ZBDXZEGIXHCDMC-UHFFFAOYSA-N 50128673 1-(3-methoxybenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-(4-Butoxy-benzenesulfonyl)-1-(3-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL309311 Disintegrin and metalloproteinase domain-containing protein 17 272 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128673 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128673&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9805016 104020436 CHEMBL309311 ZINC13521106 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809804 CCOP(=O)(N1CCN(CC1C(=O)NO)C(=O)OCc1ccccc1)c1ccc(OC)cc1 InChI=1S/C22H28N3O7P/c1-3-32-33(29,19-11-9-18(30-2)10-12-19)25-14-13-24(15-20(25)21(26)23-28)22(27)31-16-17-7-5-4-6-8-17/h4-12,20,28H,3,13-16H2,1-2H3,(H,23,26) LXKHXLQQHKRMFP-UHFFFAOYSA-N 50109637 4-[Ethoxy-(4-methoxy-phenyl)-phosphinoyl]-3-hydroxycarbamoyl-piperazine-1-carboxylic acid benzyl ester::CHEMBL173235 Disintegrin and metalloproteinase domain-containing protein 17 7.99 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109637&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384755 104004577 CHEMBL173235 ZINC28014064 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809806 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(cc1)-c1ccccc1 InChI=1S/C24H25N2O4P/c1-2-30-31(29,22-14-12-19(13-15-22)18-8-4-3-5-9-18)26-17-21-11-7-6-10-20(21)16-23(26)24(27)25-28/h3-15,23,28H,2,16-17H2,1H3,(H,25,27) PTSHMCCZVCAMNJ-UHFFFAOYSA-N 50109626 Biphenyl-4-yl-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester::CHEMBL539171 Disintegrin and metalloproteinase domain-containing protein 17 50 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109626 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109626&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384761 104004566 CHEMBL539171 ZINC28006713 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809810 CCOCCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C21H27N2O6P/c1-3-28-12-13-29-30(26,19-10-8-18(27-2)9-11-19)23-15-17-7-5-4-6-16(17)14-20(23)21(24)22-25/h4-11,20,25H,3,12-15H2,1-2H3,(H,22,24) GMNFREWQYNXZAF-UHFFFAOYSA-N 50109634 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-ethoxy-ethyl ester::CHEMBL368857 Disintegrin and metalloproteinase domain-containing protein 17 18.9 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109634 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109634&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384650 104004574 CHEMBL368857 ZINC28019857 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809811 CCOP(=O)(N1CCCC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C14H21N2O5P/c1-3-21-22(19,12-8-6-11(20-2)7-9-12)16-10-4-5-13(16)14(17)15-18/h6-9,13,18H,3-5,10H2,1-2H3,(H,15,17) MDDQQIMYYBMNMU-UHFFFAOYSA-N 50109619 (2-Hydroxycarbamoyl-pyrrolidin-1-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL172181 Disintegrin and metalloproteinase domain-containing protein 17 >780 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109619 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109619&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384455 104004559 CHEMBL172181 ZINC28013289 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809816 CCO[P@@](=O)(N1Cc2ccccc2C[C@H]1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H23N2O5P/c1-3-26-27(24,17-10-8-16(25-2)9-11-17)21-13-15-7-5-4-6-14(15)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22)/t18-,27+/m0/s1 RBLCSCFFNCADJO-XRHLQHRESA-N 50370190 CHEMBL174014 Disintegrin and metalloproteinase domain-containing protein 17 >780 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370190&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11014626 160849292 CHEMBL174014 ZINC13472472 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809826 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccccc1 InChI=1S/C18H21N2O4P/c1-2-24-25(23,16-10-4-3-5-11-16)20-13-15-9-7-6-8-14(15)12-17(20)18(21)19-22/h3-11,17,22H,2,12-13H2,1H3,(H,19,21) MXGYLPKHTGTZKG-UHFFFAOYSA-N 50109628 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenyl-phosphinic acid ethyl ester::CHEMBL172548 Disintegrin and metalloproteinase domain-containing protein 17 11.2 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109628 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109628&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384649 104004568 CHEMBL172548 ZINC28013497 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809830 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(N)cc1 InChI=1S/C18H22N3O4P/c1-2-25-26(24,16-9-7-15(19)8-10-16)21-12-14-6-4-3-5-13(14)11-17(21)18(22)20-23/h3-10,17,23H,2,11-12,19H2,1H3,(H,20,22) XRIFBRFEZLXEFP-UHFFFAOYSA-N 50109623 (4-Amino-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester::CHEMBL436049 Disintegrin and metalloproteinase domain-containing protein 17 75.8 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109623 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109623&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384004 104004563 CHEMBL436049 ZINC28005614 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809836 CCOP(=O)(N1Cc2ccsc2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C17H21N2O5PS/c1-3-24-25(22,14-6-4-13(23-2)5-7-14)19-11-12-8-9-26-16(12)10-15(19)17(20)18-21/h4-9,15,21H,3,10-11H2,1-2H3,(H,18,20) CDUNTBSHRUTDFM-UHFFFAOYSA-N 50109624 (6-Hydroxycarbamoyl-6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL173316 Disintegrin and metalloproteinase domain-containing protein 17 6.45 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109624 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109624&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384756 104004564 CHEMBL173316 ZINC28014068 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809837 CCO[P@](=O)(N1Cc2ccccc2C[C@H]1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H23N2O5P/c1-3-26-27(24,17-10-8-16(25-2)9-11-17)21-13-15-7-5-4-6-14(15)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22)/t18-,27-/m0/s1 RBLCSCFFNCADJO-MYUZEXMDSA-N 50370192 CHEMBL418655 Disintegrin and metalloproteinase domain-containing protein 17 >780 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370192 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370192&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10916140 160849294 CHEMBL418655 ZINC13472471 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809847 CCCCCCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C23H31N2O5P/c1-3-4-5-8-15-30-31(28,21-13-11-20(29-2)12-14-21)25-17-19-10-7-6-9-18(19)16-22(25)23(26)24-27/h6-7,9-14,22,27H,3-5,8,15-17H2,1-2H3,(H,24,26) FITSVZFOIGFQQI-UHFFFAOYSA-N 50109639 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid hexyl ester::CHEMBL170429 Disintegrin and metalloproteinase domain-containing protein 17 32.7 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109639 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109639&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384814 104004579 CHEMBL170429 ZINC28006821 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809849 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1cccs1 InChI=1S/C16H19N2O4PS/c1-2-22-23(21,15-8-5-9-24-15)18-11-13-7-4-3-6-12(13)10-14(18)16(19)17-20/h3-9,14,20H,2,10-11H2,1H3,(H,17,19) HFCXLBPJFPHTAN-UHFFFAOYSA-N 50109640 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-thiophen-2-yl-phosphinic acid ethyl ester::CHEMBL367710 Disintegrin and metalloproteinase domain-containing protein 17 59.6 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109640&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384003 104004580 CHEMBL367710 ZINC28010293 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809851 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1cccc(F)c1 InChI=1S/C18H20FN2O4P/c1-2-25-26(24,16-9-5-8-15(19)11-16)21-12-14-7-4-3-6-13(14)10-17(21)18(22)20-23/h3-9,11,17,23H,2,10,12H2,1H3,(H,20,22) KADFIIKJGHEHDF-UHFFFAOYSA-N 50109632 (3-Fluoro-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester::CHEMBL172415 Disintegrin and metalloproteinase domain-containing protein 17 22.8 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109632&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384357 104004572 CHEMBL172415 ZINC28015180 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809852 COc1ccc(cc1)P(=O)(OCCc1ccccn1)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C24H26N3O5P/c1-31-21-9-11-22(12-10-21)33(30,32-15-13-20-8-4-5-14-25-20)27-17-19-7-3-2-6-18(19)16-23(27)24(28)26-29/h2-12,14,23,29H,13,15-17H2,1H3,(H,26,28) TZNUGSCRBFBAFR-UHFFFAOYSA-N 50109631 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-pyridin-2-yl-ethyl ester::CHEMBL173027 Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109631&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384542 104004571 CHEMBL173027 ZINC28020191 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809858 CCOP(=O)(\C=C\c1ccccc1)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C20H23N2O4P/c1-2-26-27(25,13-12-16-8-4-3-5-9-16)22-15-18-11-7-6-10-17(18)14-19(22)20(23)21-24/h3-13,19,24H,2,14-15H2,1H3,(H,21,23)/b13-12+ IAZFWEJODMHVIO-OUKQBFOZSA-N 50109611 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-styryl-phosphinic acid ethyl ester::CHEMBL172722 Disintegrin and metalloproteinase domain-containing protein 17 37.40 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109611&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384592 104004551 CHEMBL172722 ZINC28017108 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50799370 CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)[C@H](CSCC#C)C(=O)NO InChI=1S/C22H31N3O4S/c1-5-11-30-14-18(21(27)25-29)17(12-15(2)3)20(26)24-19(22(28)23-4)13-16-9-7-6-8-10-16/h1,6-10,15,17-19,29H,11-14H2,2-4H3,(H,23,28)(H,24,26)(H,25,27)/t17-,18+,19+/m1/s1 FVTCRHGTLFGMDE-QYZOEREBSA-N 50084689 CHEMBL430888::N*4*-Hydroxy-2-isobutyl-N*1*-(1-methylcarbamoyl-2-phenyl-ethyl)-3-prop-2-ynylsulfanylmethyl-succinamide Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm990412m 10.7270/Q2JD4XH4 10669559 Leung, D; Abbenante, G; Fairlie, DP University of Queensland http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50084689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50084689&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44342378 103984219 CHEMBL430888 ZINC03821457 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812250 COc1ccc(cc1)S(=O)(=O)C(Cc1ccc2ccccc2c1)C(=O)NO InChI=1S/C20H19NO5S/c1-26-17-8-10-18(11-9-17)27(24,25)19(20(22)21-23)13-14-6-7-15-4-2-3-5-16(15)12-14/h2-12,19,23H,13H2,1H3,(H,21,22) JRBJMWFZOMECPK-UHFFFAOYSA-N 50128606 CHEMBL307252::N-Hydroxy-2-(4-methoxy-benzenesulfonyl)-3-naphthalen-2-yl-propionamide::N-hydroxy-2-(4-methoxyphenylsulfonyl)-3-(naphthalen-2-yl)propanamide Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128606&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11014504 104020369 CHEMBL307252 ZINC13520752 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812260 CCCCCCCCC(Cc1cccnc1)(C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C23H32N2O5S/c1-3-4-5-6-7-8-15-23(22(26)25-27,17-19-10-9-16-24-18-19)31(28,29)21-13-11-20(30-2)12-14-21/h9-14,16,18,27H,3-8,15,17H2,1-2H3,(H,25,26) IQNGGJYKFADFHE-UHFFFAOYSA-N 50128612 (R)-N-hydroxy-2-(4-methoxyphenylsulfonyl)-2-(pyridin-3-ylmethyl)decanamide::2-(4-Methoxy-benzenesulfonyl)-2-pyridin-3-ylmethyl-decanoic acid hydroxyamide::CHEMBL77425 Disintegrin and metalloproteinase domain-containing protein 17 669 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128612&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10275589 104020375 CHEMBL77425 ZINC34801919 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812278 COc1ccc(cc1)S(=O)(=O)C(C)(CC1CCCCC1)C(=O)NO InChI=1S/C17H25NO5S/c1-17(16(19)18-20,12-13-6-4-3-5-7-13)24(21,22)15-10-8-14(23-2)9-11-15/h8-11,13,20H,3-7,12H2,1-2H3,(H,18,19) VEUYFZWVWBJLBT-UHFFFAOYSA-N 50128600 (S)-3-cyclohexyl-N-hydroxy-2-(4-methoxyphenylsulfonyl)-2-methylpropanamide::3-Cyclohexyl-N-hydroxy-2-(4-methoxy-benzenesulfonyl)-2-methyl-propionamide::CHEMBL80361 Disintegrin and metalloproteinase domain-containing protein 17 180 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128600 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128600&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9924798 104020363 CHEMBL80361 ZINC13520808 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812292 COc1ccc(cc1)S(=O)(=O)C(C)(CC=C(C)C)C(=O)NO InChI=1S/C15H21NO5S/c1-11(2)9-10-15(3,14(17)16-18)22(19,20)13-7-5-12(21-4)6-8-13/h5-9,18H,10H2,1-4H3,(H,16,17) COEXRWHXVMMHEF-UHFFFAOYSA-N 50128620 2-(4-Methoxy-benzenesulfonyl)-2-methyl-4-methylene-hex-5-enoic acid hydroxyamide::CHEMBL311304 Disintegrin and metalloproteinase domain-containing protein 17 626 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128620 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128620&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9840355 104020383 CHEMBL311304 ZINC13520771 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812314 COc1ccc(cc1)S(=O)(=O)C(CC=C(C)C)(CC=C(C)C)C(=O)NO InChI=1S/C19H27NO5S/c1-14(2)10-12-19(18(21)20-22,13-11-15(3)4)26(23,24)17-8-6-16(25-5)7-9-17/h6-11,22H,12-13H2,1-5H3,(H,20,21) XGMBTNMILCXDFB-UHFFFAOYSA-N 50128610 2-(4-Methoxy-benzenesulfonyl)-4-methylene-2-(2-methylene-but-3-enyl)-hex-5-enoic acid hydroxyamide::CHEMBL310688 Disintegrin and metalloproteinase domain-containing protein 17 805 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128610&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11825105 104020373 CHEMBL310688 ZINC03820502 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812318 COc1ccc(cc1)S(=O)(=O)C(CC=C(C)C)(Cc1cccnc1)C(=O)NO InChI=1S/C20H24N2O5S/c1-15(2)10-11-20(19(23)22-24,13-16-5-4-12-21-14-16)28(25,26)18-8-6-17(27-3)7-9-18/h4-10,12,14,24H,11,13H2,1-3H3,(H,22,23) QDJTVBZWIYKRMZ-UHFFFAOYSA-N 50128617 2-(4-Methoxy-benzenesulfonyl)-4-methylene-2-pyridin-3-ylmethyl-hex-5-enoic acid hydroxyamide::CHEMBL76888 Disintegrin and metalloproteinase domain-containing protein 17 203 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128617 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128617&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 17897285 104020380 CHEMBL76888 ZINC13520822 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812321 CCCCC(Cc1cccnc1)(C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C19H24N2O5S/c1-3-4-11-19(18(22)21-23,13-15-6-5-12-20-14-15)27(24,25)17-9-7-16(26-2)8-10-17/h5-10,12,14,23H,3-4,11,13H2,1-2H3,(H,21,22) KDSNJNDUIRTNNR-UHFFFAOYSA-N 50128602 (R)-N-hydroxy-2-(4-methoxyphenylsulfonyl)-2-(pyridin-3-ylmethyl)hexanamide::2-(4-Methoxy-benzenesulfonyl)-2-pyridin-3-ylmethyl-hexanoic acid hydroxyamide::CHEMBL309530 Disintegrin and metalloproteinase domain-containing protein 17 764 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128602 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128602&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10200532 104020365 CHEMBL309530 ZINC13520845 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812335 CCCCCCCCCCCCC(C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 InChI=1S/C21H35NO5S/c1-3-4-5-6-7-8-9-10-11-12-13-20(21(23)22-24)28(25,26)19-16-14-18(27-2)15-17-19/h14-17,20,24H,3-13H2,1-2H3,(H,22,23) ZGEUEQMPAIUHSM-UHFFFAOYSA-N 50128625 2-(4-Methoxy-benzenesulfonyl)-tetradecanoic acid hydroxyamide::CHEMBL77207::N-hydroxy-2-(4-methoxyphenylsulfonyl)tetradecanamide Disintegrin and metalloproteinase domain-containing protein 17 942 ChEMBL 10.1021/jm0205548 10.7270/Q2RR1ZZJ 12773041 Aranapakam, V; Grosu, GT; Davis, JM; Hu, B; Ellingboe, J; Baker, JL; Skotnicki, JS; Zask, A; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128625&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11101735 104020388 CHEMBL77207 ZINC34801934 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812355 CC(C)CCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccccc2)CC1)C(=O)NO InChI=1S/C24H32N2O5S/c1-19(2)12-17-31-21-8-10-22(11-9-21)32(29,30)24(23(27)25-28)13-15-26(16-14-24)18-20-6-4-3-5-7-20/h3-11,19,28H,12-18H2,1-2H3,(H,25,27) CXFQYPXLXLPGNM-UHFFFAOYSA-N 50128630 1-Benzyl-4-[4-(3-methyl-butoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-N-hydroxy-4-(4-(isopentyloxy)phenylsulfonyl)piperidine-4-carboxamide::CHEMBL78508 Disintegrin and metalloproteinase domain-containing protein 17 565 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128630&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9847092 104020393 CHEMBL78508 ZINC13521097 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812357 COc1ccc(CN2CCC(CC2)(C(=O)NO)S(=O)(=O)c2ccc(OC)cc2)cc1 InChI=1S/C21H26N2O6S/c1-28-17-5-3-16(4-6-17)15-23-13-11-21(12-14-23,20(24)22-25)30(26,27)19-9-7-18(29-2)8-10-19/h3-10,25H,11-15H2,1-2H3,(H,22,24) KLYIBVBIKFMTRO-UHFFFAOYSA-N 50128632 1-(4-methoxybenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-Methoxy-benzenesulfonyl)-1-(4-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL76856 Disintegrin and metalloproteinase domain-containing protein 17 197 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128632 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128632&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9889128 104020395 CHEMBL76856 ZINC13521030 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812360 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)[C@H](C(C)C)C(=O)NO InChI=1S/C18H23N3O5S/c1-13(2)17(18(22)20-23)21(12-14-5-4-10-19-11-14)27(24,25)16-8-6-15(26-3)7-9-16/h4-11,13,17,23H,12H2,1-3H3,(H,20,22)/t17-/m1/s1 BSIZUMJRKYHEBR-QGZVFWFLSA-N 8465 (2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylmethyl)sulfonamido]-3-methylbutanamide::BMCL16311 Compound 1a::CGS 27023::CGS 27023A::CHEMBL514138::hydroxamate analogue 1 Disintegrin and metalloproteinase domain-containing protein 17 231 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=8465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=8465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search CGS 4AYK,1JIZ,2W0D,3AYK 446504 11109211 CHEMBL514138 DB07556 ZINC06302114 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812361 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(C)cc2)CC1)C(=O)NO InChI=1S/C21H26N2O5S/c1-16-3-5-17(6-4-16)15-23-13-11-21(12-14-23,20(24)22-25)29(26,27)19-9-7-18(28-2)8-10-19/h3-10,25H,11-15H2,1-2H3,(H,22,24) CWVWYGJTCDBSIW-UHFFFAOYSA-N 50128637 4-(4-Methoxy-benzenesulfonyl)-1-(4-methyl-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL77176 Disintegrin and metalloproteinase domain-containing protein 17 222 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128637 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128637&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9888280 104020400 CHEMBL77176 ZINC13520965 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812368 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(cc2)-c2cccs2)CC1)C(=O)NO InChI=1S/C24H26N2O5S2/c1-31-20-8-10-21(11-9-20)33(29,30)24(23(27)25-28)12-14-26(15-13-24)17-18-4-6-19(7-5-18)22-3-2-16-32-22/h2-11,16,28H,12-15,17H2,1H3,(H,25,27) RHTOEITZKIINCY-UHFFFAOYSA-N 50128642 1-(4-(thiophen-2-yl)benzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-Methoxy-benzenesulfonyl)-1-(4-thiophen-2-yl-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL80183 Disintegrin and metalloproteinase domain-containing protein 17 273 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128642 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128642&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9913301 104020405 CHEMBL80183 ZINC13521110 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812374 COc1ccc(cc1)S(=O)(=O)C1(CCN(CCc2ccccc2)CC1)C(=O)NO InChI=1S/C21H26N2O5S/c1-28-18-7-9-19(10-8-18)29(26,27)21(20(24)22-25)12-15-23(16-13-21)14-11-17-5-3-2-4-6-17/h2-10,25H,11-16H2,1H3,(H,22,24) KASLMAICRUMQME-UHFFFAOYSA-N 50128646 4-(4-Methoxy-benzenesulfonyl)-1-phenethyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL310057::N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-phenethylpiperidine-4-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 470 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128646 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128646&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9953817 104020409 CHEMBL310057 ZINC13521039 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812375 Cc1ccc(CN2CCC(CC2)(C(=O)NO)S(=O)(=O)c2ccc(OCc3ccc(Cl)cc3)cc2)cc1 InChI=1S/C27H29ClN2O5S/c1-20-2-4-21(5-3-20)18-30-16-14-27(15-17-30,26(31)29-32)36(33,34)25-12-10-24(11-13-25)35-19-22-6-8-23(28)9-7-22/h2-13,32H,14-19H2,1H3,(H,29,31) GWQPVXKPORBEIM-UHFFFAOYSA-N 50128647 4-[4-(4-chloro-benzyloxy)-benzenesulfonyl]-1-(4-methyl-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL312432 Disintegrin and metalloproteinase domain-containing protein 17 421 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128647 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128647&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9958604 104020410 CHEMBL312432 ZINC13521118 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812376 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(CCCOc2ccccc2)CC1)C(=O)NO InChI=1S/C25H34N2O6S/c1-2-3-19-32-22-10-12-23(13-11-22)34(30,31)25(24(28)26-29)14-17-27(18-15-25)16-7-20-33-21-8-5-4-6-9-21/h4-6,8-13,29H,2-3,7,14-20H2,1H3,(H,26,28) WWVKBGIBCFSFOJ-UHFFFAOYSA-N 50128631 4-(4-Butoxy-benzenesulfonyl)-1-(3-phenoxy-propyl)-piperidine-4-carboxylic acid hydroxyamide::4-(4-butoxyphenylsulfonyl)-N-hydroxy-1-(3-phenoxypropyl)piperidine-4-carboxamide::CHEMBL78611 Disintegrin and metalloproteinase domain-containing protein 17 631 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128631 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128631&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9913489 104020394 CHEMBL78611 ZINC13521052 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809698 CCOP(=O)(N1Cc2cc(N)ccc2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H24N3O5P/c1-3-27-28(25,17-8-6-16(26-2)7-9-17)22-12-14-10-15(20)5-4-13(14)11-18(22)19(23)21-24/h4-10,18,24H,3,11-12,20H2,1-2H3,(H,21,23) DPQCHTZYBRQXQC-UHFFFAOYSA-N 50109610 (7-Amino-3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL171962 Disintegrin and metalloproteinase domain-containing protein 17 37.40 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109610 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109610&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384343 104004550 CHEMBL171962 ZINC28019233 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809701 CCOP(=O)(CCc1ccccc1)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C20H25N2O4P/c1-2-26-27(25,13-12-16-8-4-3-5-9-16)22-15-18-11-7-6-10-17(18)14-19(22)20(23)21-24/h3-11,19,24H,2,12-15H2,1H3,(H,21,23) DWFUVVZGNJNHKO-UHFFFAOYSA-N 50109613 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phenethyl-phosphinic acid ethyl ester::CHEMBL175164 Disintegrin and metalloproteinase domain-containing protein 17 14.2 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109613&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384972 104004553 CHEMBL175164 ZINC28090011 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809702 CCOCCOc1ccc(cc1)P(=O)(OCC)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C22H29N2O6P/c1-3-28-13-14-29-19-9-11-20(12-10-19)31(27,30-4-2)24-16-18-8-6-5-7-17(18)15-21(24)22(25)23-26/h5-12,21,26H,3-4,13-16H2,1-2H3,(H,23,25) SQYRXZTYDRVAMZ-UHFFFAOYSA-N 50109614 CHEMBL353536::[4-(2-Ethoxy-ethoxy)-phenyl]-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester Disintegrin and metalloproteinase domain-containing protein 17 2.98 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109614 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109614&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384762 104004554 CHEMBL353536 ZINC13438454 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809704 CCOP(=O)(N1Cc2nccnc2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C17H21N4O5P/c1-3-26-27(24,13-6-4-12(25-2)5-7-13)21-11-15-14(18-8-9-19-15)10-16(21)17(22)20-23/h4-9,16,23H,3,10-11H2,1-2H3,(H,20,22) JFMSSTVXWKCAJH-UHFFFAOYSA-N 50109616 (7-Hydroxycarbamoyl-7,8-dihydro-5H-pyrido[3,4-b]pyrazin-6-yl)-(4-methoxy-phenyl)-phosphinic acid ethyl ester::CHEMBL177072 Disintegrin and metalloproteinase domain-containing protein 17 13.7 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109616 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109616&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11731926 104004556 CHEMBL177072 ZINC28090126 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809714 CCO[P@](=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H23N2O5P/c1-3-26-27(24,17-10-8-16(25-2)9-11-17)21-13-15-7-5-4-6-14(15)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22)/t18?,27-/m0/s1 RBLCSCFFNCADJO-UEEDVJNSSA-N 50370191 CHEMBL366478 Disintegrin and metalloproteinase domain-containing protein 17 7.15 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370191 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370191&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10949166 160849293 CHEMBL366478 ZINC13472471 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809715 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccccc1F InChI=1S/C18H20FN2O4P/c1-2-25-26(24,17-10-6-5-9-15(17)19)21-12-14-8-4-3-7-13(14)11-16(21)18(22)20-23/h3-10,16,23H,2,11-12H2,1H3,(H,20,22) PIHNCDLSZQOOPU-UHFFFAOYSA-N 50109612 (2-Fluoro-phenyl)-(3-hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-phosphinic acid ethyl ester::CHEMBL173326 Disintegrin and metalloproteinase domain-containing protein 17 73.60 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109612 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109612&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44384173 104004552 CHEMBL173326 ZINC28008603 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809717 CCN(CC)CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C23H32N3O5P/c1-4-25(5-2)14-15-31-32(29,21-12-10-20(30-3)11-13-21)26-17-19-9-7-6-8-18(19)16-22(26)23(27)24-28/h6-13,22,28H,4-5,14-17H2,1-3H3,(H,24,27) NQUUIXIBNFFYTG-UHFFFAOYSA-N 50109615 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid 2-diethylamino-ethyl ester::CHEMBL171292 Disintegrin and metalloproteinase domain-containing protein 17 33.2 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109615&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383704 104004555 CHEMBL171292 ZINC28007297 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809719 CCOP(=O)(N1Cc2ccccc2CC1C(=O)NO)c1ccc(Oc2ccncc2)cc1 InChI=1S/C23H24N3O5P/c1-2-30-32(29,21-9-7-19(8-10-21)31-20-11-13-24-14-12-20)26-16-18-6-4-3-5-17(18)15-22(26)23(27)25-28/h3-14,22,28H,2,15-16H2,1H3,(H,25,27) IBUXWZOBVVWCHD-UHFFFAOYSA-N 50109625 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-[4-(pyridin-4-yloxy)-phenyl]-phosphinic acid ethyl ester::CHEMBL173686 Disintegrin and metalloproteinase domain-containing protein 17 13.8 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109625 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109625&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383829 104004565 CHEMBL173686 ZINC28012883 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809730 CCO[P@@](=O)(N1Cc2ccccc2C[C@H]1C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H23N2O5P/c1-3-26-27(24,17-10-8-16(25-2)9-11-17)21-13-15-7-5-4-6-14(15)12-18(21)19(22)20-23/h4-11,18,23H,3,12-13H2,1-2H3,(H,20,22)/t18-,27+/m0/s1 RBLCSCFFNCADJO-XRHLQHRESA-N 50370190 CHEMBL174014 Disintegrin and metalloproteinase domain-containing protein 17 >780 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50370190 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50370190&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11014626 160849292 CHEMBL174014 ZINC13472472 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50809736 COc1ccc(cc1)P(=O)(OC)N1Cc2ccccc2CC1C(=O)NO InChI=1S/C18H21N2O5P/c1-24-15-7-9-16(10-8-15)26(23,25-2)20-12-14-6-4-3-5-13(14)11-17(20)18(21)19-22/h3-10,17,22H,11-12H2,1-2H3,(H,19,21) RTKNMWBYPISZDZ-UHFFFAOYSA-N 50109630 (3-Hydroxycarbamoyl-3,4-dihydro-1H-isoquinolin-2-yl)-(4-methoxy-phenyl)-phosphinic acid methyl ester::CHEMBL170315 Disintegrin and metalloproteinase domain-containing protein 17 8.92 ChEMBL 10.1021/jm0103211 10.7270/Q2XK8G9Q 11831904 Sawa, M; Kiyoi, T; Kurokawa, K; Kumihara, H; Yamamoto, M; Miyasaka, T; Ito, Y; Hirayama, R; Inoue, T; Kirii, Y; Nishiwaki, E; Ohmoto, H; Maeda, Y; Ishibushi, E; Inoue, Y; Yoshino, K; Kondo, H Nippon Organon K.K. http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50109630 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50109630&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44383789 104004570 CHEMBL170315 ZINC28005890 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812385 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(OC)cc2)CC1)C(=O)NO InChI=1S/C24H32N2O6S/c1-3-4-17-32-21-9-11-22(12-10-21)33(29,30)24(23(27)25-28)13-15-26(16-14-24)18-19-5-7-20(31-2)8-6-19/h5-12,28H,3-4,13-18H2,1-2H3,(H,25,27) NAXMTMYDSBOGMZ-UHFFFAOYSA-N 50128643 1-(4-methoxybenzyl)-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-(4-Butoxy-benzenesulfonyl)-1-(4-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL78478 Disintegrin and metalloproteinase domain-containing protein 17 208 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128643 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128643&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9826275 104020406 CHEMBL78478 ZINC13521044 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812392 ONC(=O)C1(CS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CCOCC1 InChI=1S/C19H20ClNO6S/c20-14-1-3-15(4-2-14)27-16-5-7-17(8-6-16)28(24,25)13-19(18(22)21-23)9-11-26-12-10-19/h1-8,23H,9-13H2,(H,21,22) ROSNVSQTEGHUKU-UHFFFAOYSA-N 11863 4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N-hydroxyoxane-4-carboxamide::CHEMBL440498::RS 130830::RS-130,830::alpha-tetrahydropyran beta-sulfone 1B Disintegrin and metalloproteinase domain-containing protein 17 176 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11863 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11863&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search RS1 830C 3342298 46512375 CHEMBL440498 DB08490 ZINC01488366 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812394 ONC(=O)C1(CCNCC1)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1 InChI=1S/C18H19ClN2O5S/c19-13-1-3-14(4-2-13)26-15-5-7-16(8-6-15)27(24,25)18(17(22)21-23)9-11-20-12-10-18/h1-8,20,23H,9-12H2,(H,21,22) HHLQXXSIVVEBOY-UHFFFAOYSA-N 50128656 4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL80732 Disintegrin and metalloproteinase domain-containing protein 17 848 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128656 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128656&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10938505 104020419 CHEMBL80732 ZINC13521093 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812395 ONC(=O)C1(CCN(Cc2ccccc2)CC1)S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C26H28N2O5S/c29-25(27-30)26(15-17-28(18-16-26)19-21-7-3-1-4-8-21)34(31,32)24-13-11-23(12-14-24)33-20-22-9-5-2-6-10-22/h1-14,30H,15-20H2,(H,27,29) ATFPFLNWBZIBTJ-UHFFFAOYSA-N 50128654 1-Benzyl-4-(4-benzyloxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-Benzyl-4-(4-phenoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-4-(4-(benzyloxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL78369 Disintegrin and metalloproteinase domain-containing protein 17 416 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128654 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128654&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9913053 104020417 CHEMBL78369 ZINC13521077 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812403 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO InChI=1S/C16H23NO6S/c1-2-3-10-23-13-4-6-14(7-5-13)24(20,21)16(15(18)17-19)8-11-22-12-9-16/h4-7,19H,2-3,8-12H2,1H3,(H,17,18) MIMMUUIYLKITIG-UHFFFAOYSA-N 50128659 4-(4-Butoxy-benzenesulfonyl)-tetrahydro-pyran-4-carboxylic acid hydroxyamide::CHEMBL310340 Disintegrin and metalloproteinase domain-containing protein 17 177 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128659 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128659&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11142863 104020422 CHEMBL310340 ZINC26470828 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812404 COc1ccc(CN2CCC(CC2)(C(=O)NO)S(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)cc1 InChI=1S/C26H27ClN2O6S/c1-34-21-6-2-19(3-7-21)18-29-16-14-26(15-17-29,25(30)28-31)36(32,33)24-12-10-23(11-13-24)35-22-8-4-20(27)5-9-22/h2-13,31H,14-18H2,1H3,(H,28,30) WZTNVCMELDPHHH-UHFFFAOYSA-N 50128649 1-(4-methoxybenzyl)-4-(4-(4-chlorophenoxy)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-(4-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL78909 Disintegrin and metalloproteinase domain-containing protein 17 492 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128649 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128649&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11734162 104020412 CHEMBL78909 ZINC26481270 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812417 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2cccc(OC)c2)CC1)C(=O)NO InChI=1S/C21H26N2O6S/c1-28-17-6-8-19(9-7-17)30(26,27)21(20(24)22-25)10-12-23(13-11-21)15-16-4-3-5-18(14-16)29-2/h3-9,14,25H,10-13,15H2,1-2H3,(H,22,24) LCQNQVIUMDNDJS-UHFFFAOYSA-N 50128657 1-(3-methoxybenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::4-(4-Methoxy-benzenesulfonyl)-1-(3-methoxy-benzyl)-piperidine-4-carboxylic acid hydroxyamide::CHEMBL276119 Disintegrin and metalloproteinase domain-containing protein 17 213 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128657 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128657&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9954605 104020420 CHEMBL276119 ZINC13520956 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812423 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccccc2)CC1)C(=O)NO InChI=1S/C23H30N2O5S/c1-2-3-17-30-20-9-11-21(12-10-20)31(28,29)23(22(26)24-27)13-15-25(16-14-23)18-19-7-5-4-6-8-19/h4-12,27H,2-3,13-18H2,1H3,(H,24,26) SRPXVKQVZQEPFT-UHFFFAOYSA-N 50128667 1-Benzyl-4-(4-butoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-4-(4-butoxyphenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL309492 Disintegrin and metalloproteinase domain-containing protein 17 154 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128667 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128667&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9846418 104020430 CHEMBL309492 ZINC13521017 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812425 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2cccc(OCCN3CCOCC3)c2)CC1)C(=O)NO InChI=1S/C29H41N3O7S/c1-2-3-18-38-25-7-9-27(10-8-25)40(35,36)29(28(33)30-34)11-13-32(14-12-29)23-24-5-4-6-26(22-24)39-21-17-31-15-19-37-20-16-31/h4-10,22,34H,2-3,11-21,23H2,1H3,(H,30,33) DDHYHOSBNZTEDO-UHFFFAOYSA-N 50128640 4-(4-Butoxy-benzenesulfonyl)-1-[3-(2-morpholin-4-yl-ethoxy)-benzyl]-piperidine-4-carboxylic acid hydroxyamide::CHEMBL80911 Disintegrin and metalloproteinase domain-containing protein 17 506 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128640 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128640&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10886343 104020403 CHEMBL80911 ZINC26470175 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812426 ONC(=O)C1(CCN(Cc2ccccc2)CC1)S(=O)(=O)c1ccc(cc1)-c1ccco1 InChI=1S/C23H24N2O5S/c26-22(24-27)23(12-14-25(15-13-23)17-18-5-2-1-3-6-18)31(28,29)20-10-8-19(9-11-20)21-7-4-16-30-21/h1-11,16,27H,12-15,17H2,(H,24,26) JZKQUJKQSKTEON-UHFFFAOYSA-N 50128658 1-Benzyl-4-(4-furan-2-yl-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-benzyl-4-(4-(furan-2-yl)phenylsulfonyl)-N-hydroxypiperidine-4-carboxamide::CHEMBL311436 Disintegrin and metalloproteinase domain-containing protein 17 416 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128658 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128658&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11112993 104020421 CHEMBL311436 ZINC13521122 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812428 CCCCOc1ccc(cc1)S(=O)(=O)C1(CCN(CCCC)CC1)C(=O)NO InChI=1S/C20H32N2O5S/c1-3-5-13-22-14-11-20(12-15-22,19(23)21-24)28(25,26)18-9-7-17(8-10-18)27-16-6-4-2/h7-10,24H,3-6,11-16H2,1-2H3,(H,21,23) HUTRBECWDORHKF-UHFFFAOYSA-N 50128666 4-(4-Butoxy-benzenesulfonyl)-1-butyl-piperidine-4-carboxylic acid hydroxyamide::4-(4-butoxyphenylsulfonyl)-1-butyl-N-hydroxypiperidine-4-carboxamide::CHEMBL420023 Disintegrin and metalloproteinase domain-containing protein 17 880 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128666 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128666&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9931505 104020429 CHEMBL420023 ZINC13521073 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50812430 COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(F)cc2)CC1)C(=O)NO InChI=1S/C20H23FN2O5S/c1-28-17-6-8-18(9-7-17)29(26,27)20(19(24)22-25)10-12-23(13-11-20)14-15-2-4-16(21)5-3-15/h2-9,25H,10-14H2,1H3,(H,22,24) HYZDHISHDZBYBQ-UHFFFAOYSA-N 50128655 1-(4-Fluoro-benzyl)-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-(4-fluorobenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::CHEMBL309416 Disintegrin and metalloproteinase domain-containing protein 17 250 ChEMBL 10.1021/jm0205550 10.7270/Q2N0178C 12773042 Aranapakam, V; Davis, JM; Grosu, GT; Baker, J; Ellingboe, J; Zask, A; Levin, JI; Sandanayaka, VP; Du, M; Skotnicki, JS; DiJoseph, JF; Sung, A; Sharr, MA; Killar, LM; Walter, T; Jin, G; Cowling, R; Tillett, J; Zhao, W; McDevitt, J; Xu, ZB Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128655 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128655&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9888485 104020418 CHEMBL309416 ZINC13521021 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50857585 N[C@@H]1CCCC[C@H]1NC(=O)P(O)(O)=O InChI=1S/C7H15N2O4P/c8-5-3-1-2-4-6(5)9-7(10)14(11,12)13/h5-6H,1-4,8H2,(H,9,10)(H2,11,12,13)/t5-,6-/m1/s1 XHCXISPZIHYKQD-PHDIDXHHSA-N 50372742 CHEMBL270296 Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1021/jm701087n 10.7270/Q2H70GN0 18257543 Hoffman, A; Qadri, B; Frant, J; Katz, Y; Bhusare, SR; Breuer, E; Hadar, R; Reich, R The Hebrew University of Jerusalem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50372742 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50372742&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 24807817 160851843 CHEMBL270296 ZINC29134636 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50857591 N[C@H]1CCCC[C@H]1NC(=O)P(O)(O)=O InChI=1S/C7H15N2O4P/c8-5-3-1-2-4-6(5)9-7(10)14(11,12)13/h5-6H,1-4,8H2,(H,9,10)(H2,11,12,13)/t5-,6+/m0/s1 XHCXISPZIHYKQD-NTSWFWBYSA-N 50234465 CHEMBL270083::cis-2-aminocyclohexylcarbamoylphosphonic acid Disintegrin and metalloproteinase domain-containing protein 17 >100000 ChEMBL 10.1021/jm701087n 10.7270/Q2H70GN0 18257543 Hoffman, A; Qadri, B; Frant, J; Katz, Y; Bhusare, SR; Breuer, E; Hadar, R; Reich, R The Hebrew University of Jerusalem http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50234465 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50234465&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44457233 104055923 CHEMBL270083 ZINC29134634 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877910 COc1ccc(cc1)-c1ccc(CN2C(CCS2(=O)=O)C(=O)NO)cc1 InChI=1S/C18H20N2O5S/c1-25-16-8-6-15(7-9-16)14-4-2-13(3-5-14)12-20-17(18(21)19-22)10-11-26(20,23)24/h2-9,17,22H,10-12H2,1H3,(H,19,21) RNCWXNOSFWYLTA-UHFFFAOYSA-N 11548 CHEMBL100570::N-hydroxy-2-[(4-methoxy-1,1-biphenyl-4-yl)methyl]isothiazolidine-3-carboxamide 1,1-dioxide::N-hydroxy-2-{[4-(4-methoxyphenyl)phenyl]methyl}-1,1-dioxo-1,2-thiazolidine-3-carboxamide::Sultam Hydroxamate 15a Disintegrin and metalloproteinase domain-containing protein 17 >1000 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=11548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=11548&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10156375 46512081 CHEMBL100570 ZINC13579358 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877911 Cc1cc(COc2ccc(cc2)N2C(CCCS2(=O)=O)C(=O)NO)c2ccccc2n1 InChI=1S/C22H23N3O5S/c1-15-13-16(19-5-2-3-6-20(19)23-15)14-30-18-10-8-17(9-11-18)25-21(22(26)24-27)7-4-12-31(25,28)29/h2-3,5-6,8-11,13,21,27H,4,7,12,14H2,1H3,(H,24,26) XVLVIDNHSWHJBN-UHFFFAOYSA-N 50177315 2-[4-(2-Methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-1lambda*6*-[1,2]thiazinane-3-carboxylic acid hydroxyamide::2-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-1,1-dioxo-[1,2]thiazinane-3-carboxylic acid hydroxyamide::CHEMBL203160 Disintegrin and metalloproteinase domain-containing protein 17 3.7 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50177315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50177315&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10225319 104062783 CHEMBL203160 ZINC28570889 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877912 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(11-12-27-18)28(24,25)15-5-3-13(4-6-15)26-14-7-9-19-10-8-14/h3-10,16,23H,11-12H2,1-2H3,(H,20,22)/t16-/m0/s1 YKPYIPVDTNNYCN-INIZCTEOSA-N 50082556 (S)-2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::(S)-N-hydroxy-2,2-dimethyl-4-(4-(pyridin-4-yloxy)phenylsulfonyl)thiomorpholine-3-carboxamide::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(AG 3340)::2,2-Dimethyl-4-[4-(pyridin-4-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide(prinomastat)::AG-3340::CHEMBL75094::Prinomastat Disintegrin and metalloproteinase domain-containing protein 17 22 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50082556 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50082556&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search PN0 3QM4,3TDA,6CSD 466151 103982334 CHEMBL75094 6505 ZINC00580328 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877913 CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)[C@H](O)C(=O)NO)C(C)(C)C InChI=1S/C15H29N3O5/c1-8(2)7-9(10(19)13(21)18-23)12(20)17-11(14(22)16-6)15(3,4)5/h8-11,19,23H,7H2,1-6H3,(H,16,22)(H,17,20)(H,18,21)/t9-,10+,11-/m1/s1 OCSMOTCMPXTDND-OUAUKWLOSA-N 50063917 (2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl]-N(1),2-dihydroxy-3-(2-methylpropyl)butanediamide::CHEMBL279785::cid_119031::marimastat Disintegrin and metalloproteinase domain-containing protein 17 3.8 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50063917 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50063917&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 097 1R55,3HY7,2JIH 119031 103959089 50662 CHEMBL279785 DB00786 5220 ZINC01544157 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877916 CNC(=O)[C@@H](NC(=O)[C@@H]([C@H](CO)C(=O)NO)c1ccc(OC)cc1)C(C)(C)C InChI=1S/C19H29N3O6/c1-19(2,3)15(18(26)20-4)21-17(25)14(13(10-23)16(24)22-27)11-6-8-12(28-5)9-7-11/h6-9,13-15,23,27H,10H2,1-5H3,(H,20,26)(H,21,25)(H,22,24)/t13-,14+,15+/m0/s1 IOLRUMINDIUCLJ-RRFJBIMHSA-N 50183784 (2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-3-(hydroxymethyl)-2-(4-methoxyphenyl)succinamide::(2S,3R)-N4-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N1-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide::CHEMBL72511::N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide::PKF-242-484::TNF-484 Disintegrin and metalloproteinase domain-containing protein 17 56 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183784&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9886977 104068215 CHEMBL72511 ZINC13473801 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877917 CNC(=O)[C@@H](NC(=O)[C@@H]([C@H](CO)C(=O)NO)c1ccc(C)cc1)C(C)(C)C InChI=1S/C19H29N3O5/c1-11-6-8-12(9-7-11)14(13(10-23)16(24)22-27)17(25)21-15(18(26)20-5)19(2,3)4/h6-9,13-15,23,27H,10H2,1-5H3,(H,20,26)(H,21,25)(H,22,24)/t13-,14+,15+/m0/s1 KNCYWVRUUBOHGE-RRFJBIMHSA-N 50240611 (2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-3-(hydroxymethyl)-2-p-tolylsuccinamide::CHEMBL306090::N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-2-hydroxymethyl-3-p-tolyl-succinamide::PKF-241-466 Disintegrin and metalloproteinase domain-containing protein 17 141 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240611 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240611&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9907830 104098376 CHEMBL306090 ZINC13473800 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877918 CC(C)C[C@H]([C@H](CC=Cc1ccccc1)C(=O)NO)C(=O)NN(CC(C)C)S(C)(=O)=O InChI=1S/C22H35N3O5S/c1-16(2)14-20(21(26)23-25(15-17(3)4)31(5,29)30)19(22(27)24-28)13-9-12-18-10-7-6-8-11-18/h6-12,16-17,19-20,28H,13-15H2,1-5H3,(H,23,26)(H,24,27)/t19-,20+/m0/s1 BACZSFOSMGICGM-VQTJNVASSA-N 50247804 (2S,3R)-2-cinnamyl-N-hydroxy-3-(2-isobutyl-2-(methylsulfonyl)hydrazinecarbonyl)-5-methylhexanamide::CHEMBL474339::Ro-32-7315 Disintegrin and metalloproteinase domain-containing protein 17 3 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247804 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247804&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9955564 104102601 CHEMBL474339 ZINC03820345 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877919 CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)[C@H](C(C)C)N(O)C=O)C(=O)Nc1ccccn1 InChI=1S/C22H36N4O4/c1-7-16(6)19(22(29)24-18-10-8-9-11-23-18)25-21(28)17(12-14(2)3)20(15(4)5)26(30)13-27/h8-11,13-17,19-20,30H,7,12H2,1-6H3,(H,25,28)(H,23,24,29)/t16-,17+,19-,20-/m0/s1 SMZPWUUYPYYHIV-HNJRGHQBSA-N 50247805 (2R,3S)-3-(N-hydroxyformamido)-2-isobutyl-4-methyl-N-((2S,3S)-3-methyl-1-oxo-1-(pyridin-2-ylamino)pentan-2-yl)pentanamide::CHEMBL514958::GW-3333 Disintegrin and metalloproteinase domain-containing protein 17 40 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247805 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247805&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 216470 104102602 CHEMBL514958 ZINC03820356 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877922 COc1ccc(cc1)S(=O)(=O)N(C)c1c(C)cc(Br)cc1C(=O)NO InChI=1S/C16H17BrN2O5S/c1-10-8-11(17)9-14(16(20)18-21)15(10)19(2)25(22,23)13-6-4-12(24-3)5-7-13/h4-9,21H,1-3H3,(H,18,20) JXCARHJPSZBVFH-UHFFFAOYSA-N 50111695 5-Bromo-N-hydroxy-2-[(4-methoxy-benzenesulfonyl)-methyl-amino]-3-methyl-benzamide::5-bromo-N-hydroxy-2-(4-methoxy-N-methylphenylsulfonamido)-3-methylbenzamide::CHEMBL18614 Disintegrin and metalloproteinase domain-containing protein 17 32 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50111695 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50111695&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 23506783 104006220 CHEMBL18614 ZINC13440690 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877924 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(ccc(Br)c1C(=O)NO)N1CCN(C)CC1 InChI=1S/C23H27BrN4O5S/c1-4-5-16-33-17-6-8-18(9-7-17)34(31,32)27(3)22-20(28-14-12-26(2)13-15-28)11-10-19(24)21(22)23(29)25-30/h6-11,30H,12-16H2,1-3H3,(H,25,29) AVPJZTNLOKMJMG-UHFFFAOYSA-N 50247821 6-bromo-2-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-3-(4-methylpiperazin-1-yl)benzamide::CHEMBL474140 Disintegrin and metalloproteinase domain-containing protein 17 25 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247821 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247821&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44564406 104102613 CHEMBL474140 ZINC44430326 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877925 CC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC(C)(C)[C@@H]1C(=O)NO InChI=1S/C17H22N2O5S2/c1-4-5-11-24-13-6-8-14(9-7-13)26(22,23)19-10-12-25-17(2,3)15(19)16(20)18-21/h6-9,15,21H,10-12H2,1-3H3,(H,18,20)/t15-/m0/s1 CVZIHNYAZLXRRS-HNNXBMFYSA-N 23498 (3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL207729::TMI-1 Disintegrin and metalloproteinase domain-containing protein 17 8.4 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23498 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23498&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search IH6 1ZXC 5288615 50091760 CHEMBL207729 DB07964 ZINC03817227 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877929 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCC#CCO)cc1 InChI=1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21)/t15-/m0/s1 MAVDNGWEBZTACC-HNNXBMFYSA-N 50181008 (S)-N-hydroxy-4-(4-(4-hydroxybut-2-ynyloxy)phenylsulfonyl)-2,2-dimethylthiomorpholine-3-carboxamide::CHEMBL206815::TMI-05::US9266848, Apratastat::US9365529, Apratastat Disintegrin and metalloproteinase domain-containing protein 17 440 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50181008 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50181008&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11452716 104065867 CHEMBL206815 6482 ZINC28571311 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877930 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(cccc12)-c1ccccc1)C(=O)NO InChI=1S/C29H24N4O5S/c1-38-22-12-14-23(15-13-22)39(36,37)33(19-20-7-6-16-30-17-20)28-25-11-5-10-24(21-8-3-2-4-9-21)27(25)31-18-26(28)29(34)32-35/h2-18,35H,19H2,1H3,(H,32,34) JRKVJTDYMGJJAK-UHFFFAOYSA-N 50126605 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-8-phenyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL290952::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-8-phenylquinoline-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126605&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10187181 104018680 CHEMBL290952 ZINC29306629 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877932 COc1cccc2c(N(C)S(=O)(=O)c3ccc(OCC#CC)cc3)c(cnc12)C(=O)NO InChI=1S/C22H21N3O6S/c1-4-5-13-31-15-9-11-16(12-10-15)32(28,29)25(2)21-17-7-6-8-19(30-3)20(17)23-14-18(21)22(26)24-27/h6-12,14,27H,13H2,1-3H3,(H,24,26) DWBZTKJXPJGGSU-UHFFFAOYSA-N 50126615 4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-8-methoxyquinoline-3-carboxamide::4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-8-methoxy-quinoline-3-carboxylic acid hydroxyamide::CHEMBL288671 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126615 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126615&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9825237 104018690 CHEMBL288671 ZINC03820770 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877936 Cc1cc(COc2ccc(cc2)C(=O)NC2(C)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C23H20N4O5/c1-13-11-15(17-5-3-4-6-18(17)24-13)12-32-16-9-7-14(8-10-16)19(28)27-23(2)20(29)25-22(31)26-21(23)30/h3-11H,12H2,1-2H3,(H,27,28)(H2,25,26,29,30,31) VXTCOPDBGATGEE-UHFFFAOYSA-N 50195927 CHEMBL391851::N-(5-methyl-2,4,6-trioxo-hexahydropyrimidin-5-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide::N-(5-methyl-2,4,6-trioxohexahydropyrimidin-5-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide Disintegrin and metalloproteinase domain-containing protein 17 0.026 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195927 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195927&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44439848 104077874 CHEMBL391851 ZINC28892530 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877937 Cc1cc(COc2ccc(cc2)C2(C)C(=O)NC(=O)NC2=O)c2ccccc2n1 InChI=1S/C22H19N3O4/c1-13-11-14(17-5-3-4-6-18(17)23-13)12-29-16-9-7-15(8-10-16)22(2)19(26)24-21(28)25-20(22)27/h3-11H,12H2,1-2H3,(H2,24,25,26,27,28) QKXIBRKQCXPSEK-UHFFFAOYSA-N 50167485 5-Methyl-5-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-pyrimidine-2,4,6-trione::5-methyl-5-(4-((2-methylquinolin-4-yl)methoxy)phenyl)pyrimidine-2,4,6(1H,3H,5H)-trione::CHEMBL193316 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50167485 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50167485&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10237492 104052720 CHEMBL193316 ZINC13980708 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877939 CCOP(=O)(N[C@@H](CC(C)C)C(=O)NO)c1ccc(OC)cc1 InChI=1S/C15H25N2O5P/c1-5-22-23(20,13-8-6-12(21-4)7-9-13)17-14(10-11(2)3)15(18)16-19/h6-9,11,14,19H,5,10H2,1-4H3,(H,16,18)(H,17,20)/t14-,23?/m0/s1 KTCRMROJXXSPQJ-JRQMZCAUSA-N 50129021 CHEMBL291361::ethyl N-(S)-1-(hydroxyamino)-4-methyl-1-oxopentan-2-yl-P-(4-methoxyphenyl)phosphonamidate::ethyl N-{(1s)-1-[(hydroxyamino)carbonyl]-3-methylbutyl}-P-(4-methoxyphenyl)phosphonamidoate Disintegrin and metalloproteinase domain-containing protein 17 76 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50129021 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50129021&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44304355 104020693 CHEMBL291361 ZINC26162518 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877940 ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 InChI=1S/C18H20N2O8S/c21-14-10-20(15(18(24)19-25)17(23)16(14)22)29(26,27)13-8-6-12(7-9-13)28-11-4-2-1-3-5-11/h1-9,14-17,21-23,25H,10H2,(H,19,24)/t14-,15+,16+,17+/m0/s1 WLWNRAWQDZRXMB-YLFCFFPRSA-N 50131385 (2R,3R,4R,5S)-3,4,5-Trihydroxy-1-(4-phenoxy-benzenesulfonyl)-piperidine-2-carboxylic acid hydroxyamide::(2R,3R,4R,5S)-N,3,4,5-tetrahydroxy-1-(4-phenoxyphenylsulfonyl)piperidine-2-carboxamide::CHEMBL61193 Disintegrin and metalloproteinase domain-containing protein 17 2.3 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131385 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131385&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910222 104022557 CHEMBL61193 6514 ZINC13537266 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877942 CCCCCCC(C(=O)NO)S(=O)c1ccc(OCC#CC)cc1 InChI=1S/C18H25NO4S/c1-3-5-7-8-9-17(18(20)19-21)24(22)16-12-10-15(11-13-16)23-14-6-4-2/h10-13,17,21H,3,5,7-9,14H2,1-2H3,(H,19,20) RBRFAUFMZOIMMS-UHFFFAOYSA-N 50156712 (S)-2-[(R)-4-but-2-ynyloxyphenylsulfinyl)octanoic Acid hydroxamide::(S)-2-[(S)-4-but-2-ynyloxyphenylsulfinyl)octanoic acid hydroxamide::2-(4-(but-2-ynyloxy)phenylsulfinyl)-N-hydroxyoctanamide::CHEMBL374219 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156712 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156712&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18324856 104043821 CHEMBL374219 ZINC13585940 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877943 C\C=C\C=C\C=C1/COC(=O)C(CCC(=O)NO)=C1 InChI=1S/C14H17NO4/c1-2-3-4-5-6-11-9-12(14(17)19-10-11)7-8-13(16)15-18/h2-6,9,18H,7-8,10H2,1H3,(H,15,16)/b3-2+,5-4+,11-6- LCTLPROJUJRGOK-FOZCRLHDSA-N 50247704 3-(5-(hexa-2,4-dienylidene)-2-oxo-5,6-dihydro-2H-pyran-3-yl)-N-hydroxypropanamide::CHEMBL455409 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247704 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247704&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44564180 104102523 CHEMBL455409 ZINC40380480 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877949 COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2onc(C)c12)C(=O)NO InChI=1S/C21H19N5O6S/c1-13-18-19(17(20(27)24-28)11-23-21(18)32-25-13)26(12-14-4-3-9-22-10-14)33(29,30)16-7-5-15(31-2)6-8-16/h3-11,28H,12H2,1-2H3,(H,24,27) ZZVSRSRVYMQUCW-UHFFFAOYSA-N 50126613 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3-methyl-isoxazolo[5,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL34418::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-3-methylisoxazolo[5,4-b]pyridine-5-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 147 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126613 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126613&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10116042 104018688 CHEMBL34418 ZINC13489442 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877950 CC#CCOc1ccc(cc1)S(=O)(=O)N(C)c1c(cnc2onc(C)c12)C(=O)NO InChI=1S/C19H18N4O6S/c1-4-5-10-28-13-6-8-14(9-7-13)30(26,27)23(3)17-15(18(24)21-25)11-20-19-16(17)12(2)22-29-19/h6-9,11,25H,10H2,1-3H3,(H,21,24) FHAJCDXKKGQJQW-UHFFFAOYSA-N 50126601 4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-3-methylisoxazolo[5,4-b]pyridine-5-carboxamide::4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-3-methyl-isoxazolo[5,4-b]pyridine-5-carboxylic acid hydroxyamide::CHEMBL36309 Disintegrin and metalloproteinase domain-containing protein 17 6 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126601 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126601&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9910544 104018676 CHEMBL36309 ZINC03924184 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877951 CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2ccc(CO)cc2N(CC1C(=O)NO)C(C)=O InChI=1S/C23H25N3O7S/c1-3-4-11-33-19-7-9-20(10-8-19)34(31,32)26-13-18-6-5-17(15-27)12-21(18)25(16(2)28)14-22(26)23(29)24-30/h5-10,12,22,27,30H,11,13-15H2,1-2H3,(H,24,29) JQGYJNKTRDAQCV-UHFFFAOYSA-N 50150246 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-8-hydroxymethyl-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::1-acetyl-4-(4-(but-2-ynyloxy)phenylsulfonyl)-N-hydroxy-8-(hydroxymethyl)-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxamide::CHEMBL183924 Disintegrin and metalloproteinase domain-containing protein 17 12 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50150246 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50150246&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10435554 104038737 CHEMBL183924 ZINC28378894 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877953 ONC(=O)[C@@H]1CC[C@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2I)cc1 InChI=1S/C19H21IN2O6S/c20-17-4-2-1-3-13(17)12-28-15-6-8-16(9-7-15)29(26,27)22-11-14(23)5-10-18(22)19(24)21-25/h1-4,6-9,14,18,23,25H,5,10-12H2,(H,21,24)/t14-,18-/m0/s1 SRINAMXXQPXTRO-KSSFIOAISA-N 50247895 (2S,5S)-N,5-dihydroxy-1-(4-(2-iodobenzyloxy)phenylsulfonyl)piperidine-2-carboxamide::CHEMBL491286 Disintegrin and metalloproteinase domain-containing protein 17 110000 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247895 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247895&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44564504 104102654 CHEMBL491286 ZINC49878113 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877955 C[C@@H]1[C@H](N(CCN1C(C)=O)S(=O)(=O)c1ccc(OCc2ccc(C)cc2)cc1)C(=O)NOCC=C InChI=1S/C25H31N3O6S/c1-5-16-34-26-25(30)24-19(3)27(20(4)29)14-15-28(24)35(31,32)23-12-10-22(11-13-23)33-17-21-8-6-18(2)7-9-21/h5-13,19,24H,1,14-17H2,2-4H3,(H,26,30)/t19-,24+/m1/s1 DDFFKEPNXVTRCY-DVECYGJZSA-N 50247896 (2S,3R)-4-acetyl-N-(allyloxy)-3-methyl-1-(4-(4-methylbenzyloxy)phenylsulfonyl)piperazine-2-carboxamide::CHEMBL491287 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247896 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247896&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44564505 104102655 CHEMBL491287 ZINC40952138 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877957 CC#CCOc1ccc(cc1)S(=O)(=O)CC1(CCN(CC1)S(=O)(=O)C(C)C)C(=O)NO InChI=1S/C20H28N2O7S2/c1-4-5-14-29-17-6-8-18(9-7-17)30(25,26)15-20(19(23)21-24)10-12-22(13-11-20)31(27,28)16(2)3/h6-9,16,24H,10-15H2,1-3H3,(H,21,23) CEVLUPQNDFOYSI-UHFFFAOYSA-N 23500 4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-N-hydroxy-1-(propane-2-sulfonyl)piperidine-4-carboxamide::CHEMBL209970::beta-sulfonyl hydroxamate analogue, 4 Disintegrin and metalloproteinase domain-containing protein 17 1.5 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23500 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23500&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11634234 50091761 CHEMBL209970 ZINC06718474 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877958 CC(C)Cc1ccc(cc1)[C@]1(C)CCN([C@H](C)C(=O)NO)C1=O InChI=1S/C18H26N2O3/c1-12(2)11-14-5-7-15(8-6-14)18(4)9-10-20(17(18)22)13(3)16(21)19-23/h5-8,12-13,23H,9-11H2,1-4H3,(H,19,21)/t13-,18+/m1/s1 NIUYUCAJYPRIRB-ACJLOTCBSA-N 50120686 (R)-N-hydroxy-2-((S)-3-(4-isobutylphenyl)-3-methyl-2-oxopyrrolidin-1-yl)propanamide::CHEMBL148118::N-Hydroxy-2-[3-(4-isobutyl-phenyl)-3-methyl-2-oxo-pyrrolidin-1-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120686 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120686&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10914151 104013728 CHEMBL148118 ZINC13491923 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877959 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)cc1)C(=O)NO InChI=1S/C23H22F6N2O4/c1-13(19(32)30-34)31-8-7-21(2,20(31)33)15-3-5-18(6-4-15)35-12-14-9-16(22(24,25)26)11-17(10-14)23(27,28)29/h3-6,9-11,13,34H,7-8,12H2,1-2H3,(H,30,32)/t13-,21+/m1/s1 WTYPBULLPNGNTN-ASSNKEHSSA-N 50120689 (R)-2-((S)-3-(4-(3,5-bis(trifluoromethyl)benzyloxy)phenyl)-3-methyl-2-oxopyrrolidin-1-yl)-N-hydroxypropanamide::2-{3-[4-(3,5-Bis-trifluoromethyl-benzyloxy)-phenyl]-3-methyl-2-oxo-pyrrolidin-1-yl}-N-hydroxy-propionamide::CHEMBL144320 Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120689 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120689&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11733862 104013731 CHEMBL144320 ZINC13491934 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877960 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO InChI=1S/C20H22N2O4/c1-14(18(23)21-25)22-13-12-20(2,19(22)24)15-8-10-17(11-9-15)26-16-6-4-3-5-7-16/h3-11,14,25H,12-13H2,1-2H3,(H,21,23)/t14-,20+/m1/s1 ADBJQPXZUYOOEQ-VLIAUNLRSA-N 50120691 (R)-N-hydroxy-2-((S)-3-methyl-2-oxo-3-(4-phenoxyphenyl)pyrrolidin-1-yl)propanamide::CHEMBL144049::N-Hydroxy-2-[3-methyl-2-oxo-3-(4-phenoxy-phenyl)-pyrrolidin-1-yl]-propionamide Disintegrin and metalloproteinase domain-containing protein 17 185 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120691 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120691&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10948209 104013733 CHEMBL144049 ZINC13491928 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877961 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(cc1)-c1ccccc1)C(=O)NO InChI=1S/C20H22N2O3/c1-14(18(23)21-25)22-13-12-20(2,19(22)24)17-10-8-16(9-11-17)15-6-4-3-5-7-15/h3-11,14,25H,12-13H2,1-2H3,(H,21,23)/t14-,20+/m1/s1 MCVFKNHXPZRVBQ-VLIAUNLRSA-N 50247572 (R)-2-((S)-3-(biphenyl-4-yl)-3-methyl-2-oxopyrrolidin-1-yl)-N-hydroxypropanamide::CHEMBL515390 Disintegrin and metalloproteinase domain-containing protein 17 13000 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247572 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247572&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10903871 104102462 CHEMBL515390 ZINC13491927 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877962 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2ccccc2)cc1)C(=O)NO InChI=1S/C21H24N2O4/c1-15(19(24)22-26)23-13-12-21(2,20(23)25)17-8-10-18(11-9-17)27-14-16-6-4-3-5-7-16/h3-11,15,26H,12-14H2,1-2H3,(H,22,24)/t15-,21+/m1/s1 BDLXCRNZHKNUCS-VFNWGFHPSA-N 50120696 (R)-2-((S)-3-(4-(benzyloxy)phenyl)-3-methyl-2-oxopyrrolidin-1-yl)-N-hydroxypropanamide::2-[3-(4-Benzyloxy-phenyl)-3-methyl-2-oxo-pyrrolidin-1-yl]-N-hydroxy-propionamide::CHEMBL357675 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50120696 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50120696&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10970628 104013738 CHEMBL357675 ZINC03820388 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877963 C[C@@H](N1CC[C@](C)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H27N3O4/c1-16-14-18(21-6-4-5-7-22(21)26-16)15-32-20-10-8-19(9-11-20)25(3)12-13-28(24(25)30)17(2)23(29)27-31/h4-11,14,17,31H,12-13,15H2,1-3H3,(H,27,29)/t17-,25+/m1/s1 YDMIPBHQKFOFQW-NSYGIPOTSA-N 26526 (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide::BMCL181958 Compound 1::CHEMBL148169::IK682 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26526 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26526&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 541 2FV5 6914621 56464963 40083 CHEMBL148169 DB07145 ZINC03820969 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877964 Cc1cc(COc2ccc(cc2)N2CC[C@](C)(CC(=O)NO)C2=O)c2ccccc2n1 InChI=1S/C24H25N3O4/c1-16-13-17(20-5-3-4-6-21(20)25-16)15-31-19-9-7-18(8-10-19)27-12-11-24(2,23(27)29)14-22(28)26-30/h3-10,13,30H,11-12,14-15H2,1-2H3,(H,26,28)/t24-/m1/s1 SMORGKKVUWCVPK-XMMPIXPASA-N 50247605 (R)-N-hydroxy-2-(3-methyl-1-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-3-yl)acetamide::CHEMBL524092 Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247605 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247605&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44564046 104102483 CHEMBL524092 ZINC42891059 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877965 CC(C)C[C@@H](N1CC[C@](N)(C1=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C27H32N4O4/c1-17(2)14-24(25(32)30-34)31-13-12-27(28,26(31)33)20-8-10-21(11-9-20)35-16-19-15-18(3)29-23-7-5-4-6-22(19)23/h4-11,15,17,24,34H,12-14,16,28H2,1-3H3,(H,30,32)/t24-,27-/m1/s1 QVNZBDLTUKCPGJ-SHQCIBLASA-N 50247606 (R)-2-((R)-3-amino-3-(4-((2-methylquinolin-4-yl)methoxy)phenyl)-2-oxopyrrolidin-1-yl)-N-hydroxy-4-methylpentanamide::BMS-561392::CHEMBL489100 Disintegrin and metalloproteinase domain-containing protein 17 0.2 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247606 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247606&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9847838 104102484 CHEMBL489100 6509 ZINC53178284 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877966 Cc1cc(OCc2ccc(NC(=O)[C@H]3CCCC[C@@H]3C(=O)NO)cc2)c2ccccc2n1 InChI=1S/C25H27N3O4/c1-16-14-23(21-8-4-5-9-22(21)26-16)32-15-17-10-12-18(13-11-17)27-24(29)19-6-2-3-7-20(19)25(30)28-31/h4-5,8-14,19-20,31H,2-3,6-7,15H2,1H3,(H,27,29)(H,28,30)/t19-,20-/m0/s1 VMQGJUBJOLUGES-PMACEKPBSA-N 50247607 (1S,2S)-N1-hydroxy-N2-(4-((2-methylquinolin-4-yloxy)methyl)phenyl)cyclohexane-1,2-dicarboxamide::CHEMBL491084 Disintegrin and metalloproteinase domain-containing protein 17 8 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247607 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247607&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44564047 104102485 CHEMBL491084 ZINC40951866 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877967 CN1CCC[C@@H]([C@H]1C(=O)Nc1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C25H28N4O4/c1-16-14-17(20-6-3-4-8-22(20)26-16)15-33-19-11-9-18(10-12-19)27-25(31)23-21(24(30)28-32)7-5-13-29(23)2/h3-4,6,8-12,14,21,23,32H,5,7,13,15H2,1-2H3,(H,27,31)(H,28,30)/t21-,23-/m0/s1 RJSKOAOWDAMMHR-GMAHTHKFSA-N 50136259 (2S,3S)-1-Methyl-piperidine-2,3-dicarboxylic acid 3-hydroxyamide 2-{[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-amide}::(2S,3S)-N3-hydroxy-1-methyl-N2-(4-((2-methylquinolin-4-yl)methoxy)phenyl)piperidine-2,3-dicarboxamide::CHEMBL134908::IM-491 Disintegrin and metalloproteinase domain-containing protein 17 6.2 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50136259 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50136259&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9889867 104026560 CHEMBL134908 ZINC03817994 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877968 CN1CCC(C1CS(=O)(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO InChI=1S/C24H27N3O5S/c1-16-13-17(20-5-3-4-6-22(20)25-16)14-32-18-7-9-19(10-8-18)33(30,31)15-23-21(24(28)26-29)11-12-27(23)2/h3-10,13,21,23,29H,11-12,14-15H2,1-2H3,(H,26,28) QPQUYVHWOXJEPM-UHFFFAOYSA-N 50152901 1-Methyl-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonylmethyl]-pyrrolidine-3-carboxylic acid hydroxyamide::CHEMBL184885::N-hydroxy-1-methyl-2-((4-((2-methylquinolin-4-yl)methoxy)phenylsulfonyl)methyl)pyrrolidine-3-carboxamide Disintegrin and metalloproteinase domain-containing protein 17 1 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50152901 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50152901&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 18002758 104040908 CHEMBL184885 ZINC36151532 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50877969 Cc1cc(COc2ccc(cc2)C(=O)N[C@@H]2CN(CC#C)C[C@@H]2C(=O)NO)c2ccccc2n1 InChI=1S/C26H26N4O4/c1-3-12-30-14-22(26(32)29-33)24(15-30)28-25(31)18-8-10-20(11-9-18)34-16-19-13-17(2)27-23-7-5-4-6-21(19)23/h1,4-11,13,22,24,33H,12,14-16H2,2H3,(H,28,31)(H,29,32)/t22-,24+/m0/s1 SIICAQVADMFEDB-LADGPHEKSA-N 50229322 (3S,4S)-N-hydroxy-4-(4-((2-methylquinolin-4-yl)methoxy)benzamido)-1-(prop-2-ynyl)pyrrolidine-3-carboxamide::CHEMBL271235 Disintegrin and metalloproteinase domain-containing protein 17 0.14 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50229322 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50229322&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11753905 104098127 CHEMBL271235 ZINC29130116 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50905199 CC[C@H](NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](OC(=O)[C@@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C)[C@@H](C)O)C(=O)N(C)[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OC InChI=1S/C59H97N9O16/c1-17-38(55(77)67(15)43(28-37-22-19-18-20-23-37)56(78)68-25-21-24-42(68)57(79)82-16)61-53(75)47(36(12)69)65-46(72)30-44(70)39(26-31(2)3)62-52(74)41(29-45(60)71)63-51(73)40(27-32(4)5)64-54(76)49(34(8)9)83-59(81)50(35(10)11)84-58(80)48(33(6)7)66(13)14/h18-20,22-23,31-36,38-44,47-50,69-70H,17,21,24-30H2,1-16H3,(H2,60,71)(H,61,75)(H,62,74)(H,63,73)(H,64,76)(H,65,72)/t36-,38+,39+,40+,41+,42+,43-,44+,47+,48+,49-,50+/m1/s1 ICOVQVRWYNMTQP-UXVOKYIZSA-N 50302109 CHEMBL568553::Grassystatin B Disintegrin and metalloproteinase domain-containing protein 17 2230 ChEMBL 10.1021/jm9009394 10.7270/Q2BG2PXP 19715320 Kwan, JC; Eksioglu, EA; Liu, C; Paul, VJ; Luesch, H University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302109 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302109&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44253976 104156470 CHEMBL568553 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50905203 CC[C@H](C)[C@@H](O)C(=O)N[C@@H](CC(C)C)C(=O)N(C)[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)[C@@H](O)CC(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N(C)[C@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)OC InChI=1S/C50H82N8O12/c1-12-31(7)43(46(65)52-28-42(62)56(9)38(26-33-18-15-14-16-19-33)49(68)58-23-17-20-37(58)50(69)70-11)55-41(61)27-39(59)34(24-29(3)4)53-45(64)36(21-22-40(51)60)57(10)48(67)35(25-30(5)6)54-47(66)44(63)32(8)13-2/h14-16,18-19,29-32,34-39,43-44,59,63H,12-13,17,20-28H2,1-11H3,(H2,51,60)(H,52,65)(H,53,64)(H,54,66)(H,55,61)/t31-,32-,34-,35-,36-,37-,38+,39-,43-,44+/m0/s1 CRTPOZWNLFMWPB-YQGVOMCUSA-N 50302108 CHEMBL569445::Grassystatin C Disintegrin and metalloproteinase domain-containing protein 17 28600 ChEMBL 10.1021/jm9009394 10.7270/Q2BG2PXP 19715320 Kwan, JC; Eksioglu, EA; Liu, C; Paul, VJ; Luesch, H University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302108 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302108&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44253975 104156469 CHEMBL569445 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50905207 COC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)N(C)C(=O)[C@H](C)NC(=O)[C@@H](NC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](OC(=O)[C@@H](OC(=O)[C@H](C(C)C)N(C)C)C(C)C)C(C)C)[C@@H](C)O InChI=1S/C58H95N9O16/c1-30(2)25-38(43(69)29-45(71)64-46(36(12)68)52(74)60-35(11)54(76)66(15)42(27-37-21-18-17-19-22-37)55(77)67-24-20-23-41(67)56(78)81-16)61-51(73)40(28-44(59)70)62-50(72)39(26-31(3)4)63-53(75)48(33(7)8)82-58(80)49(34(9)10)83-57(79)47(32(5)6)65(13)14/h17-19,21-22,30-36,38-43,46-49,68-69H,20,23-29H2,1-16H3,(H2,59,70)(H,60,74)(H,61,73)(H,62,72)(H,63,75)(H,64,71)/t35-,36+,38-,39-,40-,41-,42+,43-,46-,47-,48+,49-/m0/s1 JZYWSTGTBRHGTL-BIXXXADNSA-N 50302107 CHEMBL567893::Grassystatin A Disintegrin and metalloproteinase domain-containing protein 17 1230 ChEMBL 10.1021/jm9009394 10.7270/Q2BG2PXP 19715320 Kwan, JC; Eksioglu, EA; Liu, C; Paul, VJ; Luesch, H University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302107 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302107&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44255320 104156468 CHEMBL567893 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50905210 CNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(C)C)CC(=O)NO InChI=1S/C20H28N4O4/c1-12(2)8-13(10-18(25)24-28)19(26)23-17(20(27)21-3)9-14-11-22-16-7-5-4-6-15(14)16/h4-7,11-13,17,22,28H,8-10H2,1-3H3,(H,21,27)(H,23,26)(H,24,25)/t13-,17+/m1/s1 NITYDPDXAAFEIT-DYVFJYSZSA-N 50062351 (R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N*4*-Hydroxy-N*1*-[2-(1H-indol-3-yl)-1-methylcarbamoyl-ethyl]-2-isobutyl-succinamide::(R)-N1-((S)-3-(1H-indol-3-yl)-1-(methylamino)-1-oxopropan-2-yl)-N4-hydroxy-2-isobutylsuccinamide::3-(N-HYDROXYCARBOXAMIDO)-2-ISOBUTYLPROPANOYL-TRP-METHYLAMIDE::CHEMBL19611::Ilomastat::US9487462, ilomastat Disintegrin and metalloproteinase domain-containing protein 17 13 ChEMBL 10.1021/jm9009394 10.7270/Q2BG2PXP 19715320 Kwan, JC; Eksioglu, EA; Liu, C; Paul, VJ; Luesch, H University of Florida http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50062351 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50062351&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search GM6 2DW1,2DW0,1PWU,2ERP,2E3X,4PKW 132519 103957874 CHEMBL19611 DB02255 ZINC03780014 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50942246 Cc1c2CC[C@H](NC(=O)c3cc(nc4ccnn34)C(=O)NCc3ccc4OCC(=O)Nc4c3)c2ccc1C(O)=O InChI=1S/C28H24N6O6/c1-14-16-5-6-19(18(16)4-3-17(14)28(38)39)33-27(37)22-11-21(31-24-8-9-30-34(22)24)26(36)29-12-15-2-7-23-20(10-15)32-25(35)13-40-23/h2-4,7-11,19H,5-6,12-13H2,1H3,(H,29,36)(H,32,35)(H,33,37)(H,38,39)/t19-/m0/s1 DACARRUBIAXSBX-IBGZPJMESA-N 50386430 CHEMBL2047536 Disintegrin and metalloproteinase domain-containing protein 17 >20000 ChEMBL 10.1021/jm201152u 10.7270/Q2668F73 22175799 Gege, C; Bao, B; Bluhm, H; Boer, J; Gallagher, BM; Korniski, B; Powers, TS; Steeneck, C; Taveras, AG; Baragi, VM Alantos Pharmaceuticals AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386430 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386430&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12000718 160865513 CHEMBL2047536 ZINC84758078 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50942247 Cc1c2CC[C@H](NC(=O)c3cc(nc4c(F)cnn34)C(=O)NCc3ccc(F)c(c3)C(F)(F)F)c2ccc1C(O)=O InChI=1S/C27H20F5N5O4/c1-12-14-5-7-20(16(14)4-3-15(12)26(40)41)36-25(39)22-9-21(35-23-19(29)11-34-37(22)23)24(38)33-10-13-2-6-18(28)17(8-13)27(30,31)32/h2-4,6,8-9,11,20H,5,7,10H2,1H3,(H,33,38)(H,36,39)(H,40,41)/t20-/m0/s1 CZRLAOXITNZAJA-FQEVSTJZSA-N 50386429 CHEMBL2047537 Disintegrin and metalloproteinase domain-containing protein 17 >20000 ChEMBL 10.1021/jm201152u 10.7270/Q2668F73 22175799 Gege, C; Bao, B; Bluhm, H; Boer, J; Gallagher, BM; Korniski, B; Powers, TS; Steeneck, C; Taveras, AG; Baragi, VM Alantos Pharmaceuticals AG http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50386429 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50386429&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 12000720 160865512 CHEMBL2047537 ZINC84669115 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50964957 CCCNc1nc(NCc2cn(C)cn2)nc(n1)N1CCC[C@@H]1CNS(=O)(=O)c1ccc(CCC)cc1 InChI=1S/C25H37N9O2S/c1-4-7-19-9-11-22(12-10-19)37(35,36)29-16-21-8-6-14-34(21)25-31-23(26-13-5-2)30-24(32-25)27-15-20-17-33(3)18-28-20/h9-12,17-18,21,29H,4-8,13-16H2,1-3H3,(H2,26,27,30,31,32)/t21-/m1/s1 RNVLUWRPULKASN-OAQYLSRUSA-N 50395675 CHEMBL2164094 Disintegrin and metalloproteinase domain-containing protein 17 7900 ChEMBL 10.1021/jm300449x 10.7270/Q2RX9D6T 22891645 Deng, H; O'Keefe, H; Davie, CP; Lind, KE; Acharya, RA; Franklin, GJ; Larkin, J; Matico, R; Neeb, M; Thompson, MM; Lohr, T; Gross, JW; Centrella, PA; O'Donovan, GK; Bedard, KL; van Vloten, K; Mataruse, S; Skinner, SR; Belyanskaya, SL; Carpenter, TY; Shearer, TW; Clark, MA; Cuozzo, JW; Arico-Muendel, CC; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395675 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395675&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 71453375 163344699 CHEMBL2164094 ZINC95553120 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50964958 CCCc1ccc(cc1)S(=O)(=O)NC[C@H]1CCCN1c1nc(NCCC#N)nc(NCc2csc(n2)-c2ccccc2)n1 InChI=1S/C30H35N9O2S2/c1-2-8-22-12-14-26(15-13-22)43(40,41)34-20-25-11-6-18-39(25)30-37-28(32-17-7-16-31)36-29(38-30)33-19-24-21-42-27(35-24)23-9-4-3-5-10-23/h3-5,9-10,12-15,21,25,34H,2,6-8,11,17-20H2,1H3,(H2,32,33,36,37,38)/t25-/m1/s1 LBWXQSGZOWXNEF-RUZDIDTESA-N 50395676 CHEMBL2164113 Disintegrin and metalloproteinase domain-containing protein 17 19900 ChEMBL 10.1021/jm300449x 10.7270/Q2RX9D6T 22891645 Deng, H; O'Keefe, H; Davie, CP; Lind, KE; Acharya, RA; Franklin, GJ; Larkin, J; Matico, R; Neeb, M; Thompson, MM; Lohr, T; Gross, JW; Centrella, PA; O'Donovan, GK; Bedard, KL; van Vloten, K; Mataruse, S; Skinner, SR; Belyanskaya, SL; Carpenter, TY; Shearer, TW; Clark, MA; Cuozzo, JW; Arico-Muendel, CC; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395676 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395676&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 66560479 163344700 CHEMBL2164113 ZINC95556432 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50964959 CCCc1ccc(cc1)S(=O)(=O)NC[C@H]1CCCN1c1nc(NCc2csc(n2)-c2ccccc2)nc(NC2CC2)n1 InChI=1S/C30H36N8O2S2/c1-2-7-21-11-15-26(16-12-21)42(39,40)32-19-25-10-6-17-38(25)30-36-28(35-29(37-30)34-23-13-14-23)31-18-24-20-41-27(33-24)22-8-4-3-5-9-22/h3-5,8-9,11-12,15-16,20,23,25,32H,2,6-7,10,13-14,17-19H2,1H3,(H2,31,34,35,36,37)/t25-/m1/s1 URLQNGAYIHTGNE-RUZDIDTESA-N 50395677 CHEMBL2164111 Disintegrin and metalloproteinase domain-containing protein 17 12600 ChEMBL 10.1021/jm300449x 10.7270/Q2RX9D6T 22891645 Deng, H; O'Keefe, H; Davie, CP; Lind, KE; Acharya, RA; Franklin, GJ; Larkin, J; Matico, R; Neeb, M; Thompson, MM; Lohr, T; Gross, JW; Centrella, PA; O'Donovan, GK; Bedard, KL; van Vloten, K; Mataruse, S; Skinner, SR; Belyanskaya, SL; Carpenter, TY; Shearer, TW; Clark, MA; Cuozzo, JW; Arico-Muendel, CC; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395677 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395677&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 66560389 163344701 CHEMBL2164111 ZINC95552025 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50964960 C=CCCNc1nc(NCc2csc(n2)-c2cccs2)nc(n1)N1CCC[C@@H]1CNS(=O)(=O)c1ccc2ccccc2c1 InChI=1S/C30H32N8O2S3/c1-2-3-14-31-28-35-29(32-18-23-20-42-27(34-23)26-11-7-16-41-26)37-30(36-28)38-15-6-10-24(38)19-33-43(39,40)25-13-12-21-8-4-5-9-22(21)17-25/h2,4-5,7-9,11-13,16-17,20,24,33H,1,3,6,10,14-15,18-19H2,(H2,31,32,35,36,37)/t24-/m1/s1 MZFVSYXTBIQFNO-XMMPIXPASA-N 50395678 CHEMBL2164122 Disintegrin and metalloproteinase domain-containing protein 17 >50000 ChEMBL 10.1021/jm300449x 10.7270/Q2RX9D6T 22891645 Deng, H; O'Keefe, H; Davie, CP; Lind, KE; Acharya, RA; Franklin, GJ; Larkin, J; Matico, R; Neeb, M; Thompson, MM; Lohr, T; Gross, JW; Centrella, PA; O'Donovan, GK; Bedard, KL; van Vloten, K; Mataruse, S; Skinner, SR; Belyanskaya, SL; Carpenter, TY; Shearer, TW; Clark, MA; Cuozzo, JW; Arico-Muendel, CC; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395678 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395678&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 66560022 163344702 CHEMBL2164122 ZINC95557189 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50964961 CCCc1ccc(cc1)S(=O)(=O)NC[C@H]1CCCN1c1nc(NCCC=C)nc(NCc2csc(n2)-c2cccs2)n1 InChI=1S/C29H36N8O2S3/c1-3-5-15-30-27-34-28(31-18-22-20-41-26(33-22)25-10-7-17-40-25)36-29(35-27)37-16-6-9-23(37)19-32-42(38,39)24-13-11-21(8-4-2)12-14-24/h3,7,10-14,17,20,23,32H,1,4-6,8-9,15-16,18-19H2,2H3,(H2,30,31,34,35,36)/t23-/m1/s1 IIXODPXDUIIVAF-HSZRJFAPSA-N 50395679 CHEMBL2164121 Disintegrin and metalloproteinase domain-containing protein 17 >50000 ChEMBL 10.1021/jm300449x 10.7270/Q2RX9D6T 22891645 Deng, H; O'Keefe, H; Davie, CP; Lind, KE; Acharya, RA; Franklin, GJ; Larkin, J; Matico, R; Neeb, M; Thompson, MM; Lohr, T; Gross, JW; Centrella, PA; O'Donovan, GK; Bedard, KL; van Vloten, K; Mataruse, S; Skinner, SR; Belyanskaya, SL; Carpenter, TY; Shearer, TW; Clark, MA; Cuozzo, JW; Arico-Muendel, CC; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395679 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395679&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 66560021 163344703 CHEMBL2164121 ZINC95552862 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50964962 FC(F)(F)c1ccc(cc1)S(=O)(=O)NC[C@H]1CCCN1c1nc(NCCC=C)nc(NCc2csc(n2)-c2cccs2)n1 InChI=1S/C27H29F3N8O2S3/c1-2-3-12-31-24-35-25(32-15-19-17-42-23(34-19)22-7-5-14-41-22)37-26(36-24)38-13-4-6-20(38)16-33-43(39,40)21-10-8-18(9-11-21)27(28,29)30/h2,5,7-11,14,17,20,33H,1,3-4,6,12-13,15-16H2,(H2,31,32,35,36,37)/t20-/m1/s1 ZDDSIQGYVHATQX-HXUWFJFHSA-N 50395680 CHEMBL2164120 Disintegrin and metalloproteinase domain-containing protein 17 >50000 ChEMBL 10.1021/jm300449x 10.7270/Q2RX9D6T 22891645 Deng, H; O'Keefe, H; Davie, CP; Lind, KE; Acharya, RA; Franklin, GJ; Larkin, J; Matico, R; Neeb, M; Thompson, MM; Lohr, T; Gross, JW; Centrella, PA; O'Donovan, GK; Bedard, KL; van Vloten, K; Mataruse, S; Skinner, SR; Belyanskaya, SL; Carpenter, TY; Shearer, TW; Clark, MA; Cuozzo, JW; Arico-Muendel, CC; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395680 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395680&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 66559934 163344704 CHEMBL2164120 ZINC95556049 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50965022 C[C@@]1(O)CCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(OCc2ccc(F)cc2Cl)cc1 InChI=1S/C20H22ClFN2O6S/c1-20(26)9-2-10-24(18(20)19(25)23-27)31(28,29)16-7-5-15(6-8-16)30-12-13-3-4-14(22)11-17(13)21/h3-8,11,18,26-27H,2,9-10,12H2,1H3,(H,23,25)/t18-,20+/m0/s1 LTVIJEFEZVFIST-AZUAARDMSA-N 50168737 (2R,3R)-1-[4-(2-Chloro-4-fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide::CHEMBL187092 Disintegrin and metalloproteinase domain-containing protein 17 1.6 ChEMBL 10.1021/jm300449x 10.7270/Q2RX9D6T 22891645 Deng, H; O'Keefe, H; Davie, CP; Lind, KE; Acharya, RA; Franklin, GJ; Larkin, J; Matico, R; Neeb, M; Thompson, MM; Lohr, T; Gross, JW; Centrella, PA; O'Donovan, GK; Bedard, KL; van Vloten, K; Mataruse, S; Skinner, SR; Belyanskaya, SL; Carpenter, TY; Shearer, TW; Clark, MA; Cuozzo, JW; Arico-Muendel, CC; Morgan, BA GlaxoSmithKline http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50168737 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50168737&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44395506 104053698 CHEMBL187092 ZINC11688142 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079939 Clc1ccc(OCC(=O)NNC(=S)NCCCCC2CCCCC2)cc1 InChI=1S/C19H28ClN3O2S/c20-16-9-11-17(12-10-16)25-14-18(24)22-23-19(26)21-13-5-4-8-15-6-2-1-3-7-15/h9-12,15H,1-8,13-14H2,(H,22,24)(H2,21,23,26) JRAYHZWPXHIVJI-UHFFFAOYSA-N 50441574 CHEMBL2437163 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/j.ejmech.2013.08.027 10.7270/Q2J967TM 24044937 Maingot, L; Elbakali, J; Dumont, J; Bosc, D; Cousaert, N; Urban, A; Deglane, G; Villoutreix, B; Nagase, H; Sperandio, O; Leroux, F; Deprez, B; Deprez-Poulain, R University of Lille http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441574 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441574&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 73349535 175453891 CHEMBL2437163 ZINC96285238 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079036 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 1436 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079037 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 17 845 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079038 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 10000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079039 ONC(=O)[C@@H](CCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C25H25Br2N3O7S/c26-19-12-18(13-20(27)14-19)16-36-21-6-8-22(9-7-21)38(34,35)30-23(24(31)29-33)10-11-28-25(32)37-15-17-4-2-1-3-5-17/h1-9,12-14,23,30,33H,10-11,15-16H2,(H,28,32)(H,29,31)/t23-/m1/s1 TZCXUSWHXSLZNB-HSZRJFAPSA-N 50441214 CHEMBL2431026 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714322 175453531 CHEMBL2431026 ZINC96284910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079040 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H14Br2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) VONWNPCXOBRHMT-UHFFFAOYSA-N 50441215 CHEMBL2431021 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714082 175453532 CHEMBL2431021 ZINC96284911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079041 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 349 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079042 ONC(=O)[C@@H](CCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C25H25Br2N3O7S/c26-19-12-18(13-20(27)14-19)16-36-21-6-8-22(9-7-21)38(34,35)30-23(24(31)29-33)10-11-28-25(32)37-15-17-4-2-1-3-5-17/h1-9,12-14,23,30,33H,10-11,15-16H2,(H,28,32)(H,29,31)/t23-/m1/s1 TZCXUSWHXSLZNB-HSZRJFAPSA-N 50441214 CHEMBL2431026 Disintegrin and metalloproteinase domain-containing protein 17 825 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714322 175453531 CHEMBL2431026 ZINC96284910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079043 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H14Br2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) VONWNPCXOBRHMT-UHFFFAOYSA-N 50441215 CHEMBL2431021 Disintegrin and metalloproteinase domain-containing protein 17 840 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714082 175453532 CHEMBL2431021 ZINC96284911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079044 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 966 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079045 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 17 4272 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079046 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 5641 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079047 ONC(=O)[C@@H](CCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C25H25Br2N3O7S/c26-19-12-18(13-20(27)14-19)16-36-21-6-8-22(9-7-21)38(34,35)30-23(24(31)29-33)10-11-28-25(32)37-15-17-4-2-1-3-5-17/h1-9,12-14,23,30,33H,10-11,15-16H2,(H,28,32)(H,29,31)/t23-/m1/s1 TZCXUSWHXSLZNB-HSZRJFAPSA-N 50441214 CHEMBL2431026 Disintegrin and metalloproteinase domain-containing protein 17 9519 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714322 175453531 CHEMBL2431026 ZINC96284910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079048 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H14Br2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) VONWNPCXOBRHMT-UHFFFAOYSA-N 50441215 CHEMBL2431021 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714082 175453532 CHEMBL2431021 ZINC96284911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079049 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 14 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079050 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 17 58 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079051 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 350 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079052 ONC(=O)[C@@H](CCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C25H25Br2N3O7S/c26-19-12-18(13-20(27)14-19)16-36-21-6-8-22(9-7-21)38(34,35)30-23(24(31)29-33)10-11-28-25(32)37-15-17-4-2-1-3-5-17/h1-9,12-14,23,30,33H,10-11,15-16H2,(H,28,32)(H,29,31)/t23-/m1/s1 TZCXUSWHXSLZNB-HSZRJFAPSA-N 50441214 CHEMBL2431026 Disintegrin and metalloproteinase domain-containing protein 17 2096 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714322 175453531 CHEMBL2431026 ZINC96284910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079053 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H14Br2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) VONWNPCXOBRHMT-UHFFFAOYSA-N 50441215 CHEMBL2431021 Disintegrin and metalloproteinase domain-containing protein 17 5301 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714082 175453532 CHEMBL2431021 ZINC96284911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079054 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 419 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079055 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 17 651 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079056 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 7626 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079057 ONC(=O)[C@@H](CCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C25H25Br2N3O7S/c26-19-12-18(13-20(27)14-19)16-36-21-6-8-22(9-7-21)38(34,35)30-23(24(31)29-33)10-11-28-25(32)37-15-17-4-2-1-3-5-17/h1-9,12-14,23,30,33H,10-11,15-16H2,(H,28,32)(H,29,31)/t23-/m1/s1 TZCXUSWHXSLZNB-HSZRJFAPSA-N 50441214 CHEMBL2431026 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714322 175453531 CHEMBL2431026 ZINC96284910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079058 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H14Br2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) VONWNPCXOBRHMT-UHFFFAOYSA-N 50441215 CHEMBL2431021 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714082 175453532 CHEMBL2431021 ZINC96284911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079059 CC#CCOc1ccc(cc1)S(=O)(=O)N[C@H](CCNC(=O)OCc1ccccc1)C(=O)NO InChI=1S/C22H25N3O7S/c1-2-3-15-31-18-9-11-19(12-10-18)33(29,30)25-20(21(26)24-28)13-14-23-22(27)32-16-17-7-5-4-6-8-17/h4-12,20,25,28H,13-16H2,1H3,(H,23,27)(H,24,26)/t20-/m1/s1 YAYGKNVDBLFWFW-HXUWFJFHSA-N 50314222 (R)-benzyl 3-(4-(but-2-ynyloxy)phenylsulfonamido)-4-(hydroxyamino)-4-oxobutylcarbamate::CHEMBL1089842 Disintegrin and metalloproteinase domain-containing protein 17 26 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 45378252 104148583 CHEMBL1089842 ZINC49068563 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079060 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 17 45 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079061 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 274 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079062 ONC(=O)[C@@H](CCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C25H25Br2N3O7S/c26-19-12-18(13-20(27)14-19)16-36-21-6-8-22(9-7-21)38(34,35)30-23(24(31)29-33)10-11-28-25(32)37-15-17-4-2-1-3-5-17/h1-9,12-14,23,30,33H,10-11,15-16H2,(H,28,32)(H,29,31)/t23-/m1/s1 TZCXUSWHXSLZNB-HSZRJFAPSA-N 50441214 CHEMBL2431026 Disintegrin and metalloproteinase domain-containing protein 17 1391 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714322 175453531 CHEMBL2431026 ZINC96284910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079063 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H14Br2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) VONWNPCXOBRHMT-UHFFFAOYSA-N 50441215 CHEMBL2431021 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714082 175453532 CHEMBL2431021 ZINC96284911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079087 NC(=O)NCCC[C@@H](NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1)C(=O)NO InChI=1S/C19H22Br2N4O6S/c20-13-8-12(9-14(21)10-13)11-31-15-3-5-16(6-4-15)32(29,30)25-17(18(26)24-28)2-1-7-23-19(22)27/h3-6,8-10,17,25,28H,1-2,7,11H2,(H,24,26)(H3,22,23,27)/t17-/m1/s1 QTXVPJOTKLUYMQ-QGZVFWFLSA-N 50441212 CHEMBL2431028 Disintegrin and metalloproteinase domain-containing protein 17 1.9 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441212 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441212&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714324 175453529 CHEMBL2431028 ZINC96284908 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079088 ONC(=O)[C@@H](CCCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C26H27Br2N3O7S/c27-20-13-19(14-21(28)15-20)17-37-22-8-10-23(11-9-22)39(35,36)31-24(25(32)30-34)7-4-12-29-26(33)38-16-18-5-2-1-3-6-18/h1-3,5-6,8-11,13-15,24,31,34H,4,7,12,16-17H2,(H,29,33)(H,30,32)/t24-/m1/s1 HJLAUHYNMNIAAR-XMMPIXPASA-N 50441213 CHEMBL2431027 Disintegrin and metalloproteinase domain-containing protein 17 11 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441213 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441213&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714323 175453530 CHEMBL2431027 ZINC96284909 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079089 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(F)cc(F)c2)cc1 InChI=1S/C15H14F2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) WVHOOIOSMOLBGZ-UHFFFAOYSA-N 50441219 CHEMBL2431020 Disintegrin and metalloproteinase domain-containing protein 17 82 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441219 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441219&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714081 175453536 CHEMBL2431020 ZINC96284915 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079090 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cccc3cccnc23)cc1 InChI=1S/C18H17N3O5S/c22-17(21-23)11-20-27(24,25)16-8-6-15(7-9-16)26-12-14-4-1-3-13-5-2-10-19-18(13)14/h1-10,20,23H,11-12H2,(H,21,22) GPJRFRUTVIKWFY-UHFFFAOYSA-N 50441220 CHEMBL2431019 Disintegrin and metalloproteinase domain-containing protein 17 650 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441220&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713868 175453537 CHEMBL2431019 ZINC96284916 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079091 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cccc(c2)-c2ccccc2)cc1 InChI=1S/C21H20N2O5S/c24-21(23-25)14-22-29(26,27)20-11-9-19(10-12-20)28-15-16-5-4-8-18(13-16)17-6-2-1-3-7-17/h1-13,22,25H,14-15H2,(H,23,24) URIKLEJPYMMEBH-UHFFFAOYSA-N 50441221 CHEMBL2431018 Disintegrin and metalloproteinase domain-containing protein 17 76 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441221&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713867 175453538 CHEMBL2431018 ZINC96284917 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079092 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cccc(OC(F)(F)F)c2)cc1 InChI=1S/C16H15F3N2O6S/c17-16(18,19)27-13-3-1-2-11(8-13)10-26-12-4-6-14(7-5-12)28(24,25)20-9-15(22)21-23/h1-8,20,23H,9-10H2,(H,21,22) RMRVSLSYZNRHKL-UHFFFAOYSA-N 50441222 CHEMBL2431017 Disintegrin and metalloproteinase domain-containing protein 17 280 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713866 175453539 CHEMBL2431017 ZINC96284918 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079093 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cccc(F)c2)cc1 InChI=1S/C15H15FN2O5S/c16-12-3-1-2-11(8-12)10-23-13-4-6-14(7-5-13)24(21,22)17-9-15(19)18-20/h1-8,17,20H,9-10H2,(H,18,19) IVQNYNVXTUYYFR-UHFFFAOYSA-N 50441223 CHEMBL2431016 Disintegrin and metalloproteinase domain-containing protein 17 71 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713865 175453540 CHEMBL2431016 ZINC96284919 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079094 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cccc(Br)c2)cc1 InChI=1S/C15H15BrN2O5S/c16-12-3-1-2-11(8-12)10-23-13-4-6-14(7-5-13)24(21,22)17-9-15(19)18-20/h1-8,17,20H,9-10H2,(H,18,19) YGTYRNSBOZPWFY-UHFFFAOYSA-N 50441224 CHEMBL2431015 Disintegrin and metalloproteinase domain-containing protein 17 104 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441224&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713864 175453541 CHEMBL2431015 ZINC96284920 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079095 ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(cc2)-c2ccccc2)cc1 InChI=1S/C21H20N2O5S/c24-21(23-25)14-22-29(26,27)20-12-10-19(11-13-20)28-15-16-6-8-18(9-7-16)17-4-2-1-3-5-17/h1-13,22,25H,14-15H2,(H,23,24) LGTBURVEOHTXLS-UHFFFAOYSA-N 50441225 CHEMBL2431032 Disintegrin and metalloproteinase domain-containing protein 17 640 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441225&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713863 175453542 CHEMBL2431032 ZINC96284921 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079096 ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(OC(F)(F)F)cc2)cc1 InChI=1S/C16H15F3N2O6S/c17-16(18,19)27-13-3-1-11(2-4-13)10-26-12-5-7-14(8-6-12)28(24,25)20-9-15(22)21-23/h1-8,20,23H,9-10H2,(H,21,22) APPNLLFVKPQJGQ-UHFFFAOYSA-N 50441226 CHEMBL2431031 Disintegrin and metalloproteinase domain-containing protein 17 200 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441226&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713862 175453543 CHEMBL2431031 ZINC96284922 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079097 ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1 InChI=1S/C15H15FN2O5S/c16-12-3-1-11(2-4-12)10-23-13-5-7-14(8-6-13)24(21,22)17-9-15(19)18-20/h1-8,17,20H,9-10H2,(H,18,19) VCASEBIJMMTOBI-UHFFFAOYSA-N 50441227 CHEMBL2431030 Disintegrin and metalloproteinase domain-containing protein 17 145 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441227&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713639 175453544 CHEMBL2431030 ZINC96284923 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079098 ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccc(Br)cc2)cc1 InChI=1S/C15H15BrN2O5S/c16-12-3-1-11(2-4-12)10-23-13-5-7-14(8-6-13)24(21,22)17-9-15(19)18-20/h1-8,17,20H,9-10H2,(H,18,19) QPWBTJDQYIYLND-UHFFFAOYSA-N 50441228 CHEMBL2431029 Disintegrin and metalloproteinase domain-containing protein 17 16 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441228&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72713638 175453545 CHEMBL2431029 ZINC96284924 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079099 ONC(=O)CNS(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C15H16N2O5S/c18-15(17-19)10-16-23(20,21)14-8-6-13(7-9-14)22-11-12-4-2-1-3-5-12/h1-9,16,19H,10-11H2,(H,17,18) ZVJILQAAQQNBOP-UHFFFAOYSA-N 50429818 CHEMBL2337691 Disintegrin and metalloproteinase domain-containing protein 17 590 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50429818 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50429818&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 71652216 164158693 CHEMBL2337691 ZINC95588506 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079100 ONC(=O)[C@@H](CCNC(=O)OCc1ccccc1)NS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C25H25Br2N3O7S/c26-19-12-18(13-20(27)14-19)16-36-21-6-8-22(9-7-21)38(34,35)30-23(24(31)29-33)10-11-28-25(32)37-15-17-4-2-1-3-5-17/h1-9,12-14,23,30,33H,10-11,15-16H2,(H,28,32)(H,29,31)/t23-/m1/s1 TZCXUSWHXSLZNB-HSZRJFAPSA-N 50441214 CHEMBL2431026 Disintegrin and metalloproteinase domain-containing protein 17 43 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441214 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441214&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714322 175453531 CHEMBL2431026 ZINC96284910 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079101 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(c2)-c2cccnc2)cc1 InChI=1S/C20H18BrN3O5S/c21-17-9-14(8-16(10-17)15-2-1-7-22-11-15)13-29-18-3-5-19(6-4-18)30(27,28)23-12-20(25)24-26/h1-11,23,26H,12-13H2,(H,24,25) AACHNFJXJZIPFX-UHFFFAOYSA-N 50441216 CHEMBL2431025 Disintegrin and metalloproteinase domain-containing protein 17 500 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441216 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441216&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72711513 175453533 CHEMBL2431025 ZINC96284912 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079102 COc1ccc(cc1)-c1cc(Br)cc(COc2ccc(cc2)S(=O)(=O)NCC(=O)NO)c1 InChI=1S/C22H21BrN2O6S/c1-30-19-4-2-16(3-5-19)17-10-15(11-18(23)12-17)14-31-20-6-8-21(9-7-20)32(28,29)24-13-22(26)25-27/h2-12,24,27H,13-14H2,1H3,(H,25,26) HPKAGMQWGBOAOT-UHFFFAOYSA-N 50441217 CHEMBL2431024 Disintegrin and metalloproteinase domain-containing protein 17 320 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441217 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441217&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714085 175453534 CHEMBL2431024 ZINC96284913 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079103 OC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H13Br2NO5S/c16-11-5-10(6-12(17)7-11)9-23-13-1-3-14(4-2-13)24(21,22)18-8-15(19)20/h1-7,18H,8-9H2,(H,19,20) QXELZFZRJLTGNV-UHFFFAOYSA-N 50441229 CHEMBL2431023 Disintegrin and metalloproteinase domain-containing protein 17 >50000 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441229&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714084 175453546 CHEMBL2431023 ZINC96284925 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079104 CN(CC(=O)NO)S(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C16H16Br2N2O5S/c1-20(9-16(21)19-22)26(23,24)15-4-2-14(3-5-15)25-10-11-6-12(17)8-13(18)7-11/h2-8,22H,9-10H2,1H3,(H,19,21) JFSQCRNERBWFRT-UHFFFAOYSA-N 50441218 CHEMBL2431022 Disintegrin and metalloproteinase domain-containing protein 17 160 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441218 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441218&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714083 175453535 CHEMBL2431022 ZINC96284914 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079105 CC#CCOc1ccc(cc1)S(=O)(=O)NCC(=O)NO InChI=1S/C12H14N2O5S/c1-2-3-8-19-10-4-6-11(7-5-10)20(17,18)13-9-12(15)14-16/h4-7,13,16H,8-9H2,1H3,(H,14,15) XRLMAIWPTHLVKY-UHFFFAOYSA-N 50131516 2-(4-(but-2-ynyloxy)phenylsulfonamido)-N-hydroxyacetamide::2-(4-But-2-ynyloxy-benzenesulfonylamino)-N-hydroxy-acetamide::CHEMBL94715 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50131516 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50131516&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9966028 104022654 CHEMBL94715 ZINC13537372 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51079106 ONC(=O)CNS(=O)(=O)c1ccc(OCc2cc(Br)cc(Br)c2)cc1 InChI=1S/C15H14Br2N2O5S/c16-11-5-10(6-12(17)7-11)9-24-13-1-3-14(4-2-13)25(22,23)18-8-15(20)19-21/h1-7,18,21H,8-9H2,(H,19,20) VONWNPCXOBRHMT-UHFFFAOYSA-N 50441215 CHEMBL2431021 Disintegrin and metalloproteinase domain-containing protein 17 105 ChEMBL 10.1021/jm4011753 10.7270/Q2DR2WZ0 24044434 Nuti, E; Casalini, F; Santamaria, S; Fabbi, M; Carbotti, G; Ferrini, S; Marinelli, L; La Pietra, V; Novellino, E; Camodeca, C; Orlandini, E; Nencetti, S; Rossello, A Università di Pisa http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50441215 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50441215&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 72714082 175453532 CHEMBL2431021 ZINC96284911 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51087989 CCCC1S\C(NC1=O)=C\c1nc2ccccc2[nH]1 InChI=1S/C14H15N3OS/c1-2-5-11-14(18)17-13(19-11)8-12-15-9-6-3-4-7-10(9)16-12/h3-4,6-8,11H,2,5H2,1H3,(H,15,16)(H,17,18)/b13-8+ VVXZPLQFCWCGBS-MDWZMJQESA-N 50445402 CHEMBL3104658 Disintegrin and metalloproteinase domain-containing protein 17 21000 ChEMBL 10.1016/j.ejmech.2013.10.075 10.7270/Q2F76F15 24316668 Sogame, S; Suenaga, Y; Atobe, M; Kawanishi, M; Tanaka, E; Miyoshi, S Asahi Kasei Pharma Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50445402 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50445402&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 76335569 194943298 CHEMBL3104658 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51087990 OC(=O)CCc1sc(\C=C2/NC(=O)CS2)nc1-c1ccccn1 InChI=1S/C15H13N3O3S2/c19-11-8-22-12(17-11)7-13-18-15(9-3-1-2-6-16-9)10(23-13)4-5-14(20)21/h1-3,6-7H,4-5,8H2,(H,17,19)(H,20,21)/b12-7+ FXCKSJPZDBQRLO-KPKJPENVSA-N 50431947 CHEMBL2348091 Disintegrin and metalloproteinase domain-containing protein 17 >30000 ChEMBL 10.1016/j.ejmech.2013.10.075 10.7270/Q2F76F15 24316668 Sogame, S; Suenaga, Y; Atobe, M; Kawanishi, M; Tanaka, E; Miyoshi, S Asahi Kasei Pharma Corporation http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431947 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431947&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 71554128 164160822 CHEMBL2348091 ZINC95601814 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015632 CC1(C)SCCN([C@H]1C(=O)NO)S(=O)(=O)c1ccc(Oc2cccnc2)cc1 InChI=1S/C18H21N3O5S2/c1-18(2)16(17(22)20-23)21(10-11-27-18)28(24,25)15-7-5-13(6-8-15)26-14-4-3-9-19-12-14/h3-9,12,16,23H,10-11H2,1-2H3,(H,20,22)/t16-/m0/s1 YTRMRJDVKQXSIU-INIZCTEOSA-N 50106026 (S)-2,2-Dimethyl-4-[4-(pyridin-3-yloxy)-benzenesulfonyl]-thiomorpholine-3-carboxylic acid hydroxyamide::CHEMBL318484 Disintegrin and metalloproteinase domain-containing protein 17 7.9 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106026 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106026&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330198 104001606 CHEMBL318484 ZINC26739271 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50015633 CNC(=O)[C@@H]1Cc2ccc(OCCCC[C@@H]([C@@H](CCCc3cc(OC)ccc3OC)C(=O)N1)C(=O)NO)cc2 InChI=1S/C29H39N3O7/c1-30-29(35)25-17-19-10-12-21(13-11-19)39-16-5-4-8-24(28(34)32-36)23(27(33)31-25)9-6-7-20-18-22(37-2)14-15-26(20)38-3/h10-15,18,23-25,36H,4-9,16-17H2,1-3H3,(H,30,35)(H,31,33)(H,32,34)/t23-,24+,25+/m1/s1 LBQUSUPCYKIDFL-DSITVLBTSA-N 50106018 (7S,8R,11S)-8-[3-(2,5-dimethoxy-phenyl)-propyl]-9-oxo-2-oxa-10-aza-bicyclo[11.2.2]heptadeca-1(16),13(17),14-triene-7,11-dicarboxylic acid 7-hydroxyamide 11-methylamide::CHEMBL99120 Disintegrin and metalloproteinase domain-containing protein 17 4100 ChEMBL 10.1016/s0960-894x(01)00603-5 10.7270/Q2C828MX 11677124 Holms, J; Mast, K; Marcotte, P; Elmore, I; Li, J; Pease, L; Glaser, K; Morgan, D; Michaelides, M; Davidsen, S Abbott Laboratories http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50106018 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50106018&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44330094 104001598 CHEMBL99120 ZINC26730827 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985360 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2cccc3ccccc23)cc1 InChI=1S/C23H24N2O6S/c26-18-8-13-22(23(27)24-28)25(14-18)32(29,30)20-11-9-19(10-12-20)31-15-17-6-3-5-16-4-1-2-7-21(16)17/h1-7,9-12,18,22,26,28H,8,13-15H2,(H,24,27)/t18-,22-/m1/s1 FYZJGFHMVNBOIV-XMSQKQJNSA-N 50113025 (2R,5R)-5-Hydroxy-1-[4-(naphthalen-1-ylmethoxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL31315 Disintegrin and metalloproteinase domain-containing protein 17 2000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113025 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113025&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9955696 104007376 CHEMBL31315 ZINC13441652 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985361 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccc(F)cc2)cc1 InChI=1S/C19H21FN2O6S/c20-14-3-1-13(2-4-14)12-28-16-5-7-17(8-6-16)29(26,27)22-10-9-15(23)11-18(22)19(24)21-25/h1-8,15,18,23,25H,9-12H2,(H,21,24)/t15-,18+/m0/s1 FCLQINRREQAAHO-MAUKXSAKSA-N 50113024 (2R,4S)-1-[4-(4-Fluoro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL285591 Disintegrin and metalloproteinase domain-containing protein 17 12000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113024 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113024&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9867022 104007375 CHEMBL285591 ZINC13441607 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985364 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 InChI=1S/C20H21F3N2O6S/c21-20(22,23)17-4-2-1-3-13(17)12-31-15-5-7-16(8-6-15)32(29,30)25-10-9-14(26)11-18(25)19(27)24-28/h1-8,14,18,26,28H,9-12H2,(H,24,27)/t14-,18+/m0/s1 CXDRRXBTMPCKQG-KBXCAEBGSA-N 50113027 (2R,4S)-4-Hydroxy-1-[4-(2-trifluoromethyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL283711 Disintegrin and metalloproteinase domain-containing protein 17 16000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113027 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113027&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10096444 104007378 CHEMBL283711 ZINC13441629 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985367 CC(C)c1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC[C@@H]1C(=O)NO InChI=1S/C22H28N2O6S/c1-15(2)20-6-4-3-5-16(20)14-30-18-8-10-19(11-9-18)31(28,29)24-13-17(25)7-12-21(24)22(26)23-27/h3-6,8-11,15,17,21,25,27H,7,12-14H2,1-2H3,(H,23,26)/t17-,21-/m1/s1 XMCYAYXTCCGUCU-DYESRHJHSA-N 50113039 (2R,5R)-5-Hydroxy-1-[4-(2-isopropyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29068 Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113039 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113039&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278395 104007390 CHEMBL29068 ZINC13441650 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985370 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccc(cc2)C#N)cc1 InChI=1S/C20H21N3O6S/c21-12-14-1-3-15(4-2-14)13-29-17-5-7-18(8-6-17)30(27,28)23-10-9-16(24)11-19(23)20(25)22-26/h1-8,16,19,24,26H,9-11,13H2,(H,22,25)/t16-,19+/m0/s1 CLPSJCJXXQNCHD-QFBILLFUSA-N 50113042 (2R,4S)-1-[4-(4-Cyano-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL414597 Disintegrin and metalloproteinase domain-containing protein 17 77000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113042 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113042&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278532 104007393 CHEMBL414597 ZINC13441630 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985371 Cc1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC[C@@H]1C(=O)NO InChI=1S/C20H24N2O6S/c1-14-4-2-3-5-15(14)13-28-17-7-9-18(10-8-17)29(26,27)22-12-16(23)6-11-19(22)20(24)21-25/h2-5,7-10,16,19,23,25H,6,11-13H2,1H3,(H,21,24)/t16-,19-/m1/s1 RADBGCOAJQAKKE-VQIMIIECSA-N 50113044 (2R,5R)-5-Hydroxy-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL31294 Disintegrin and metalloproteinase domain-containing protein 17 3000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113044 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113044&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278449 104007395 CHEMBL31294 ZINC13441648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985372 CCc1ccccc1COc1ccc(cc1)S(=O)(=O)N1C[C@H](O)CC[C@@H]1C(=O)NO InChI=1S/C21H26N2O6S/c1-2-15-5-3-4-6-16(15)14-29-18-8-10-19(11-9-18)30(27,28)23-13-17(24)7-12-20(23)21(25)22-26/h3-6,8-11,17,20,24,26H,2,7,12-14H2,1H3,(H,22,25)/t17-,20-/m1/s1 XXUCOZXCPFTGGY-YLJYHZDGSA-N 50113045 (2R,5R)-1-[4-(2-Ethyl-benzyloxy)-benzenesulfonyl]-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29069 Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113045 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113045&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278396 104007396 CHEMBL29069 ZINC03820648 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985373 ONC(=O)[C@H]1C[C@@H](O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2Cl)cc1 InChI=1S/C19H21ClN2O6S/c20-17-4-2-1-3-13(17)12-28-15-5-7-16(8-6-15)29(26,27)22-10-9-14(23)11-18(22)19(24)21-25/h1-8,14,18,23,25H,9-12H2,(H,21,24)/t14-,18+/m0/s1 RIYWMJMELHHCTR-KBXCAEBGSA-N 50113022 (2R,4S)-1-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]-4-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28646 Disintegrin and metalloproteinase domain-containing protein 17 40000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113022 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113022&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9932958 104007373 CHEMBL28646 ZINC13441617 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985381 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1 InChI=1S/C19H22N2O6S/c22-15-6-11-18(19(23)20-24)21(12-15)28(25,26)17-9-7-16(8-10-17)27-13-14-4-2-1-3-5-14/h1-5,7-10,15,18,22,24H,6,11-13H2,(H,20,23)/t15-,18-/m1/s1 GIGWICZCQGBJDH-CRAIPNDOSA-N 50113048 (2R,5R)-1-(4-Benzyloxy-benzenesulfonyl)-5-hydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL29007 Disintegrin and metalloproteinase domain-containing protein 17 14000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113048 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113048&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278484 104007399 CHEMBL29007 ZINC13441636 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985382 ONC(=O)[C@H]1CC[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2I)cc1 InChI=1S/C19H21IN2O6S/c20-17-4-2-1-3-13(17)12-28-15-6-8-16(9-7-15)29(26,27)22-11-14(23)5-10-18(22)19(24)21-25/h1-4,6-9,14,18,23,25H,5,10-12H2,(H,21,24)/t14-,18-/m1/s1 SRINAMXXQPXTRO-RDTXWAMCSA-N 50113046 (2R,5R)-5-Hydroxy-1-[4-(2-iodo-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL285272 Disintegrin and metalloproteinase domain-containing protein 17 1000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113046 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113046&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44278705 104007397 CHEMBL285272 ZINC29205554 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50985384 Cc1ccccc1COc1ccc(cc1)S(=O)(=O)N1CC[C@H](O)C[C@@H]1C(=O)NO InChI=1S/C20H24N2O6S/c1-14-4-2-3-5-15(14)13-28-17-6-8-18(9-7-17)29(26,27)22-11-10-16(23)12-19(22)20(24)21-25/h2-9,16,19,23,25H,10-13H2,1H3,(H,21,24)/t16-,19+/m0/s1 KZFRIHIZMZYZCN-QFBILLFUSA-N 50113028 (2R,4S)-4-Hydroxy-1-[4-(2-methyl-benzyloxy)-benzenesulfonyl]-piperidine-2-carboxylic acid hydroxyamide::CHEMBL28358 Disintegrin and metalloproteinase domain-containing protein 17 12000 ChEMBL 10.1016/s0960-894x(02)00183-x 10.7270/Q2GQ6X30 11992783 Letavic, MA; Axt, MZ; Barberia, JT; Carty, TJ; Danley, DE; Geoghegan, KF; Halim, NS; Hoth, LR; Kamath, AV; Laird, ER; Lopresti-Morrow, LL; McClure, KF; Mitchell, PG; Natarajan, V; Noe, MC; Pandit, J; Reeves, L; Schulte, GK; Snow, SL; Sweeney, FJ; Tan, DH; Yu, CH Pfizer Inc http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50113028 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50113028&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 15541747 104007379 CHEMBL28358 ZINC13441623 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51008356 CCC[C@@H]([C@@H](CC(C)C)C(=O)C[C@@H](CCCN\C(N)=N\[N+]([O-])=O)C(=O)Nc1nccs1)N(O)C=O InChI=1S/C21H36N7O6S/c1-4-6-17(27(32)13-29)16(11-14(2)3)18(30)12-15(19(31)25-21-24-9-10-35-21)7-5-8-23-20(22)26-28(33)34/h9-10,13-17,24,32H,4-8,11-12H2,1-3H3,(H,25,31)(H3,22,23,26)/t15-,16-,17+/m1/s1 WXEXAJCZMRRGLB-ZACQAIPSSA-N 50247806 (2R,5R,6S)-6-(N-hydroxyformamido)-N-(3H-1,3-thiazol-2-yl)-5-(2-methylpropyl)-2-[3-(2-nitrocarbamimidamido)propyl]-4-oxononanamide Disintegrin and metalloproteinase domain-containing protein 17 4.3 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50247806 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50247806&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 73346608 104102603 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51008357 Cc1cc(COc2ccc(cc2)S(=O)(=O)CC(C=C2CCC(CC2)N=O)N(O)C=O)c2ccccc2n1 InChI=1S/C27H29N3O6S/c1-19-14-21(26-4-2-3-5-27(26)28-19)16-36-24-10-12-25(13-11-24)37(34,35)17-23(30(33)18-31)15-20-6-8-22(29-32)9-7-20/h2-5,10-15,18,22-23,33H,6-9,16-17H2,1H3/b20-15- WRJBRPUQVWCVQK-HKWRFOASSA-N 50146476 CHEMBL99995::N-Hydroxy-N-{1-(4-hydroxyimino-cyclohexylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide Disintegrin and metalloproteinase domain-containing protein 17 2 ChEMBL 10.1016/j.bmc.2008.11.067 10.7270/Q2WH2QWZ 19095454 DasGupta, S; Murumkar, PR; Giridhar, R; Yadav, MR The M. S. University of Baroda http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50146476 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50146476&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 90925631 104035065 CHEMBL99995 ZINC26736036 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002685 COc1ccc(cc1)[C@H]([C@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)C(=O)N1CCCCC1 InChI=1S/C23H32N4O6/c1-23(2)21(30)27(22(31)25(23)3)14-17(19(28)24-32)18(15-8-10-16(33-4)11-9-15)20(29)26-12-6-5-7-13-26/h8-11,17-18,32H,5-7,12-14H2,1-4H3,(H,24,28)/t17-,18+/m0/s1 MHYRZRJQEBSULL-ZWKOTPCHSA-N 50183782 (2R,3S)-N-hydroxy-3-(4-methoxyphenyl)-4-oxo-4-(piperidin-1-yl)-2-((3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl)butanamide::CHEMBL438964 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183782 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183782&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44411053 104068213 CHEMBL438964 ZINC34801777 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002686 CNC(=O)[C@@H](NC(=O)[C@@H]([C@H](CN1C(=O)N(C)C(C)(C)C1=O)C(=O)NO)c1ccc(OC)cc1)C(C)(C)C InChI=1S/C25H37N5O7/c1-24(2,3)18(21(33)26-6)27-20(32)17(14-9-11-15(37-8)12-10-14)16(19(31)28-36)13-30-22(34)25(4,5)29(7)23(30)35/h9-12,16-18,36H,13H2,1-8H3,(H,26,33)(H,27,32)(H,28,31)/t16-,17+,18+/m0/s1 MWYSQPGMUZLIHV-RCCFBDPRSA-N 50183783 (2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-2-(4-methoxyphenyl)-3-((3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl)succinamide::CHEMBL208181 Disintegrin and metalloproteinase domain-containing protein 17 484 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183783 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183783&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44411052 104068214 CHEMBL208181 ZINC34801776 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002687 CNC(=O)[C@@H](NC(=O)[C@@H]([C@H](CO)C(=O)NO)c1ccc(OC)cc1)C(C)(C)C InChI=1S/C19H29N3O6/c1-19(2,3)15(18(26)20-4)21-17(25)14(13(10-23)16(24)22-27)11-6-8-12(28-5)9-7-11/h6-9,13-15,23,27H,10H2,1-5H3,(H,20,26)(H,21,25)(H,22,24)/t13-,14+,15+/m0/s1 IOLRUMINDIUCLJ-RRFJBIMHSA-N 50183784 (2S,3R)-N1-((S)-3,3-dimethyl-1-(methylamino)-1-oxobutan-2-yl)-N4-hydroxy-3-(hydroxymethyl)-2-(4-methoxyphenyl)succinamide::(2S,3R)-N4-((S)-2,2-dimethyl-1-methylcarbamoyl-propyl)-N1-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide::CHEMBL72511::N*4*-(2,2-Dimethyl-1-methylcarbamoyl-propyl)-N*1*-hydroxy-2-hydroxymethyl-3-(4-methoxy-phenyl)-succinamide::PKF-242-484::TNF-484 Disintegrin and metalloproteinase domain-containing protein 17 48 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183784 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183784&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9886977 104068215 CHEMBL72511 ZINC13473801 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002688 CC[C@@H]([C@H](C(=O)N1CCCC[C@H]1C(=O)NC)c1ccc(OC)cc1)C(=O)NO InChI=1S/C20H29N3O5/c1-4-15(18(24)22-27)17(13-8-10-14(28-3)11-9-13)20(26)23-12-6-5-7-16(23)19(25)21-2/h8-11,15-17,27H,4-7,12H2,1-3H3,(H,21,25)(H,22,24)/t15-,16-,17+/m0/s1 ZQORGANDVNQVJF-YESZJQIVSA-N 50183785 (S)-1-((2S,3S)-3-(hydroxycarbamoyl)-2-(4-methoxyphenyl)pentanoyl)-N-methylpiperidine-2-carboxamide::CHEMBL207756 Disintegrin and metalloproteinase domain-containing protein 17 836 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183785 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183785&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10150649 104068216 CHEMBL207756 ZINC34323223 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002689 CC[C@@H]([C@H](C(=O)N1CCCC[C@H]1C(=O)NC)c1ccc(Cl)cc1)C(=O)NO InChI=1S/C19H26ClN3O4/c1-3-14(17(24)22-27)16(12-7-9-13(20)10-8-12)19(26)23-11-5-4-6-15(23)18(25)21-2/h7-10,14-16,27H,3-6,11H2,1-2H3,(H,21,25)(H,22,24)/t14-,15-,16+/m0/s1 NRCQPJPKKZDRND-HRCADAONSA-N 50183781 (S)-1-((2S,3S)-2-(4-chlorophenyl)-3-(hydroxycarbamoyl)pentanoyl)-N-methylpiperidine-2-carboxamide::CHEMBL382705 Disintegrin and metalloproteinase domain-containing protein 17 316 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183781 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183781&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11603611 104068212 CHEMBL382705 ZINC34801778 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002690 COc1ccc(cc1)[C@H]([C@H](CO)C(=O)NO)C(=O)N1CCCCC1 InChI=1S/C17H24N2O5/c1-24-13-7-5-12(6-8-13)15(14(11-20)16(21)18-23)17(22)19-9-3-2-4-10-19/h5-8,14-15,20,23H,2-4,9-11H2,1H3,(H,18,21)/t14-,15+/m0/s1 ZFXFRRPQPVEFAM-LSDHHAIUSA-N 50183786 (2R,3S)-N-hydroxy-2-(hydroxymethyl)-3-(4-methoxyphenyl)-4-oxo-4-(piperidin-1-yl)butanamide::CHEMBL206875 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183786 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183786&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10125869 104068217 CHEMBL206875 ZINC34269595 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002691 CN1C(=O)N(C[C@@H]([C@@H](CC2CCCC2)C(=O)N2CCCCC2)C(=O)NO)C(=O)C1(C)C InChI=1S/C22H36N4O5/c1-22(2)20(29)26(21(30)24(22)3)14-17(18(27)23-31)16(13-15-9-5-6-10-15)19(28)25-11-7-4-8-12-25/h15-17,31H,4-14H2,1-3H3,(H,23,27)/t16-,17+/m1/s1 GFUITADOEPNRML-SJORKVTESA-N 30344 Cipemastat::Trocade Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30344 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30344&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9824350 85148104 6466 ZINC00600699 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51002692 CNC(=O)[C@@H]1CCCCN1C(=O)[C@@H]([C@H](CO)C(=O)NO)c1ccc(OC)cc1 InChI=1S/C19H27N3O6/c1-20-18(25)15-5-3-4-10-22(15)19(26)16(14(11-23)17(24)21-27)12-6-8-13(28-2)9-7-12/h6-9,14-16,23,27H,3-5,10-11H2,1-2H3,(H,20,25)(H,21,24)/t14-,15-,16+/m0/s1 COUUBDFXGTZTPW-HRCADAONSA-N 50183787 (S)-1-((2S,3R)-4-(hydroxyamino)-3-(hydroxymethyl)-2-(4-methoxyphenyl)-4-oxobutanoyl)-N-methylpiperidine-2-carboxamide::CHEMBL439330 Disintegrin and metalloproteinase domain-containing protein 17 >10000 ChEMBL 10.1016/j.bmcl.2006.02.042 10.7270/Q2JS9Q12 16516469 Janser, P; Neumann, U; Miltz, W; Feifel, R; Buhl, T Novartis Institutes for BioMedical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50183787 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50183787&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10237550 104068218 CHEMBL439330 ZINC34801932 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51003900 COc1ccc(cc1)[C@@H](C(=O)NO)S(=O)c1ccc(OCC#CC)cc1 InChI=1S/C19H19NO5S/c1-3-4-13-25-16-9-11-17(12-10-16)26(23)18(19(21)20-22)14-5-7-15(24-2)8-6-14/h5-12,18,22H,13H2,1-2H3,(H,20,21)/t18-,26?/m0/s1 PCASIOOVBSODBH-MDYZWHIJSA-N 50411312 CHEMBL2096855 Disintegrin and metalloproteinase domain-containing protein 17 48 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411312 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411312&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 57127110 163360336 CHEMBL2096855 ZINC13585984 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51003902 CCCCCC[C@@H](C(=O)NO)[S@@](=O)c1ccc(OC)cc1 InChI=1S/C15H23NO4S/c1-3-4-5-6-7-14(15(17)16-18)21(19)13-10-8-12(20-2)9-11-13/h8-11,14,18H,3-7H2,1-2H3,(H,16,17)/t14-,21-/m0/s1 FROMXYGXLCSILK-QKKBWIMNSA-N 50411314 CHEMBL2096852 Disintegrin and metalloproteinase domain-containing protein 17 375 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411314 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411314&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11483818 163360338 CHEMBL2096852 ZINC13585920 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51003903 CC#CCOc1ccc(cc1)S(=O)[C@@H](C(=O)NO)c1ccccc1 InChI=1S/C18H17NO4S/c1-2-3-13-23-15-9-11-16(12-10-15)24(22)17(18(20)19-21)14-7-5-4-6-8-14/h4-12,17,21H,13H2,1H3,(H,19,20)/t17-,24?/m1/s1 LMLJZJGMFKPKNY-BPNWFJGMSA-N 50411315 CHEMBL2096739 Disintegrin and metalloproteinase domain-containing protein 17 28 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411315 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411315&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9967932 163360339 CHEMBL2096739 ZINC13585972 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51003904 CCCCCC[C@@H](C(=O)NO)S(=O)c1ccc(OCC#CC)cc1 InChI=1S/C18H25NO4S/c1-3-5-7-8-9-17(18(20)19-21)24(22)16-12-10-15(11-13-16)23-14-6-4-2/h10-13,17,21H,3,5,7-9,14H2,1-2H3,(H,19,20)/t17-,24?/m0/s1 RBRFAUFMZOIMMS-KEJDIYNNSA-N 50411313 CHEMBL2096853 Disintegrin and metalloproteinase domain-containing protein 17 4 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411313 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411313&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 9884836 163360337 CHEMBL2096853 ZINC13585936 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51003905 CCCCCC[C@@H](C(=O)NO)[S@](=O)c1ccc(OC)cc1 InChI=1S/C15H23NO4S/c1-3-4-5-6-7-14(15(17)16-18)21(19)13-10-8-12(20-2)9-11-13/h8-11,14,18H,3-7H2,1-2H3,(H,16,17)/t14-,21+/m0/s1 FROMXYGXLCSILK-LHSJRXKWSA-N 50411316 CHEMBL2096738 Disintegrin and metalloproteinase domain-containing protein 17 30 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411316 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411316&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11449819 163360340 CHEMBL2096738 ZINC13585922 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51003906 COc1ccc(cc1)[C@H](C(=O)NO)S(=O)c1ccc(OCC#CC)cc1 InChI=1S/C19H19NO5S/c1-3-4-13-25-16-9-11-17(12-10-16)26(23)18(19(21)20-22)14-5-7-15(24-2)8-6-14/h5-12,18,22H,13H2,1-2H3,(H,20,21)/t18-,26?/m1/s1 PCASIOOVBSODBH-QOBPCVTDSA-N 50411317 CHEMBL2096740 Disintegrin and metalloproteinase domain-containing protein 17 17 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411317 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411317&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 54181369 163360341 CHEMBL2096740 ZINC13585989 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 51003907 CC#CCOc1ccc(cc1)S(=O)[C@H](C(=O)NO)c1ccccc1 InChI=1S/C18H17NO4S/c1-2-3-13-23-15-9-11-16(12-10-15)24(22)17(18(20)19-21)14-7-5-4-6-8-14/h4-12,17,21H,13H2,1H3,(H,19,20)/t17-,24?/m0/s1 LMLJZJGMFKPKNY-KEJDIYNNSA-N 50411318 CHEMBL2096854 Disintegrin and metalloproteinase domain-containing protein 17 74 ChEMBL 10.1021/jm040086x 10.7270/Q21J9985 15566296 Venkatesan, AM; Davis, JM; Grosu, GT; Baker, J; Zask, A; Levin, JI; Ellingboe, J; Skotnicki, JS; Dijoseph, JF; Sung, A; Jin, G; Xu, W; McCarthy, DJ; Barone, D Wyeth Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411318 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411318&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10291146 163360342 CHEMBL2096854 ZINC13585968 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997533 CC(C)C[C@@H]1[C@H](CCCOC(=O)NCCCC[C@H](NC1=O)C(=O)Nc1ccccc1)C(=O)NO InChI=1S/C24H36N4O6/c1-16(2)15-19-18(22(30)28-33)11-8-14-34-24(32)25-13-7-6-12-20(27-21(19)29)23(31)26-17-9-4-3-5-10-17/h3-5,9-10,16,18-20,33H,6-8,11-15H2,1-2H3,(H,25,32)(H,26,31)(H,27,29)(H,28,30)/t18-,19+,20-/m0/s1 TUXNXHXUXJGQEC-ZCNNSNEGSA-N 50409220 CHEMBL89755 Disintegrin and metalloproteinase domain-containing protein 17 280 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409220 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409220&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10961787 163358244 CHEMBL89755 ZINC26579090 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997534 CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)NCC(=O)N(C)C)cc2)C(=O)NO InChI=1S/C24H36N4O6/c1-15(2)12-19-18(23(31)27-33)6-5-11-34-17-9-7-16(8-10-17)13-20(26-22(19)30)24(32)25-14-21(29)28(3)4/h7-10,15,18-20,33H,5-6,11-14H2,1-4H3,(H,25,32)(H,26,30)(H,27,31)/t18-,19+,20-/m0/s1 UFOMEAYFPTWMDE-ZCNNSNEGSA-N 50409221 CHEMBL92535 Disintegrin and metalloproteinase domain-containing protein 17 400 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409221 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409221&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10939716 163358245 CHEMBL92535 ZINC26637374 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997535 CC(C)C[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)NCC(F)(F)F)cc2)C(=O)NO InChI=1S/C22H30F3N3O5/c1-13(2)10-17-16(20(30)28-32)4-3-9-33-15-7-5-14(6-8-15)11-18(27-19(17)29)21(31)26-12-22(23,24)25/h5-8,13,16-18,32H,3-4,9-12H2,1-2H3,(H,26,31)(H,27,29)(H,28,30)/t16-,17+,18-/m0/s1 PNLMWJPYDPWVER-KSZLIROESA-N 50409222 CHEMBL314427 Disintegrin and metalloproteinase domain-containing protein 17 680 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409222 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409222&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11113492 163358246 CHEMBL314427 ZINC26579985 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997536 CNC(=O)CNC(=O)[C@@H]1CCCCNC(=O)OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO InChI=1S/C21H37N5O7/c1-13(2)11-15-14(19(29)26-32)7-6-10-33-21(31)23-9-5-4-8-16(25-18(15)28)20(30)24-12-17(27)22-3/h13-16,32H,4-12H2,1-3H3,(H,22,27)(H,23,31)(H,24,30)(H,25,28)(H,26,29)/t14-,15+,16-/m0/s1 FFSKLCWTHQRGRX-XHSDSOJGSA-N 50409223 CHEMBL90332 Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409223 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409223&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11027103 163358247 CHEMBL90332 ZINC26578055 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997537 CC(C)C[C@@H]1[C@H](CCCOC(=O)N(C)CCCC[C@H](NC1=O)C(=O)NCC(=O)N1CCN(C)CC1)C(=O)NO InChI=1S/C26H46N6O7/c1-18(2)16-20-19(24(35)29-38)8-7-15-39-26(37)31(4)10-6-5-9-21(28-23(20)34)25(36)27-17-22(33)32-13-11-30(3)12-14-32/h18-21,38H,5-17H2,1-4H3,(H,27,36)(H,28,34)(H,29,35)/t19-,20+,21-/m0/s1 BXSRLPPMIBAUNG-HBMCJLEFSA-N 50409224 CHEMBL431008 Disintegrin and metalloproteinase domain-containing protein 17 120 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409224 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409224&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11124523 163358248 CHEMBL431008 ZINC26579939 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997538 CC(C)C[C@@H]1[C@H](CCCOC(=O)N(C)CCCC[C@H](NC1=O)C(=O)NCC(=O)N1CCC(O)CC1)C(=O)NO InChI=1S/C26H45N5O8/c1-17(2)15-20-19(24(35)29-38)7-6-14-39-26(37)30(3)11-5-4-8-21(28-23(20)34)25(36)27-16-22(33)31-12-9-18(32)10-13-31/h17-21,32,38H,4-16H2,1-3H3,(H,27,36)(H,28,34)(H,29,35)/t19-,20+,21-/m0/s1 MKVUXIPUESAOLW-HBMCJLEFSA-N 50409225 CHEMBL327831 Disintegrin and metalloproteinase domain-containing protein 17 300 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409225 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409225&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10896969 163358249 CHEMBL327831 ZINC26648022 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997539 CCOC(=O)N1CCN(CC1)C(=O)CNC(=O)[C@@H]1CCCCNC(=O)OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO InChI=1S/C27H46N6O9/c1-4-41-27(39)33-13-11-32(12-14-33)22(34)17-29-25(37)21-9-5-6-10-28-26(38)42-15-7-8-19(24(36)31-40)20(16-18(2)3)23(35)30-21/h18-21,40H,4-17H2,1-3H3,(H,28,38)(H,29,37)(H,30,35)(H,31,36)/t19-,20+,21-/m0/s1 DHMSFVZDNDGURH-HBMCJLEFSA-N 50409226 CHEMBL312972 Disintegrin and metalloproteinase domain-containing protein 17 130 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409226 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409226&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11103972 163358250 CHEMBL312972 ZINC26579781 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997540 CNC(=O)[C@H](NC(=O)[C@@H]1Cc2ccc(OCCC[C@@H]([C@@H](CC(C)C)C(=O)N1)C(=O)NO)cc2)C(C)C InChI=1S/C26H40N4O6/c1-15(2)13-20-19(24(32)30-35)7-6-12-36-18-10-8-17(9-11-18)14-21(28-23(20)31)25(33)29-22(16(3)4)26(34)27-5/h8-11,15-16,19-22,35H,6-7,12-14H2,1-5H3,(H,27,34)(H,28,31)(H,29,33)(H,30,32)/t19-,20+,21-,22+/m0/s1 OXSZNRBMYYYAOO-LNRXMEIDSA-N 50409227 CHEMBL313376 Disintegrin and metalloproteinase domain-containing protein 17 1510 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409227 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409227&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 44322917 163358251 CHEMBL313376 ZINC26636939 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997541 CCCCCC[C@@H]1[C@H](CCCOc2ccc(C[C@H](NC1=O)C(=O)NCC(=O)NC)cc2)C(=O)NO InChI=1S/C25H38N4O6/c1-3-4-5-6-8-19-20(24(32)29-34)9-7-14-35-18-12-10-17(11-13-18)15-21(28-23(19)31)25(33)27-16-22(30)26-2/h10-13,19-21,34H,3-9,14-16H2,1-2H3,(H,26,30)(H,27,33)(H,28,31)(H,29,32)/t19-,20+,21+/m1/s1 HPASCPXTBGYAPJ-HKBOAZHASA-N 50409228 CHEMBL88134 Disintegrin and metalloproteinase domain-containing protein 17 550 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409228 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409228&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 10973015 163358252 CHEMBL88134 ZINC26579643 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase domain-containing protein 17 ADA17_HUMAN P78536 O60226 50997542 CC(C)C[C@@H]1[C@H](CCCOC(=O)NCCCC[C@H](NC1=O)C(=O)NCc1cccnc1)C(=O)NO InChI=1S/C24H37N5O6/c1-16(2)13-19-18(22(31)29-34)8-6-12-35-24(33)26-11-4-3-9-20(28-21(19)30)23(32)27-15-17-7-5-10-25-14-17/h5,7,10,14,16,18-20,34H,3-4,6,8-9,11-13,15H2,1-2H3,(H,26,33)(H,27,32)(H,28,30)(H,29,31)/t18-,19+,20-/m0/s1 RCOCLHFWXFEYJP-ZCNNSNEGSA-N 50409229 CHEMBL89179 Disintegrin and metalloproteinase domain-containing protein 17 500 ChEMBL 10.1021/jm010127e 10.7270/Q2FB53NR 11472217 Xue, CB; Voss, ME; Nelson, DJ; Duan, JJ; Cherney, RJ; Jacobson, IC; He, X; Roderick, J; Chen, L; Corbett, RL; Wang, L; Meyer, DT; Kennedy, K; DeGradodagger, WF; Hardman, KD; Teleha, CA; Jaffee, BD; Liu, RQ; Copeland, RA; Covington, MB; Christ, DD; Trzaskos, JM; Newton, RC; Magolda, RL; Wexler, RR; Decicco, CP DuPont Pharmaceuticals Company http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50409229 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=110&target=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50409229&enzyme=Disintegrin+and+metalloproteinase+domain-containing+protein+17&column=ki&startPg=0&Increment=50&submit=Search 11730692 163358253 CHEMBL89179 ZINC26578057 1 MRQSLLFLTSVVPFVLAPRPPDDPGFGPHQRLEKLDSLLSDYDILSLSNIQQHSVRKRDLQTSTHVETLLTFSALKRHFKLYLTSSTERFSQNFKVVVVDGKNESEYTVKWQDFFTGHVVGEPDSRVLAHIRDDDVIIRINTDGAEYNIEPLWRFVNDTKDKRMLVYKSEDIKNVSRLQSPKVCGYLKVDNEELLPKGLVDREPPEELVHRVKRRADPDPMKNTCKLLVVADHRFYRYMGRGEESTTTNYLIELIDRVDDIYRNTSWDNAGFKGYGIQIEQIRILKSPQEVKPGEKHYNMAKSYPNEEKDAWDVKMLLEQFSFDIAEEASKVCLAHLFTYQDFDMGTLGLAYVGSPRANSHGGVCPKAYYSPVGKKNIYLNSGLTSTKNYGKTILTKEADLVTTHELGHNFGAEHDPDGLAECAPNEDQGGKYVMYPIAVSGDHENNKMFSNCSKQSIYKTIESKAQECFQERSNKVCGNSRVDEGEECDPGIMYLNNDTCCNSDCTLKEGVQCSDRNSPCCKNCQFETAQKKCQEAINATCKGVSYCTGNSSECPPPGNAEDDTVCLDLGKCKDGKCIPFCEREQQLESCACNETDNSCKVCCRDLSGRCVPYVDAEQKNLFLRKGKPCTVGFCDMNGKCEKRVQDVIERFWDFIDQLSINTFGKFLADNIVGSVLVFSLIFWIPFSILVHCVDKKLDKQYESLSLFHPSNVEMLSSMDSASVRIIKPFPAPQTPGRLQPAPVIPSAPAAPKLDHQRMDTIQEDPSTDSHMDEDGFEKDPFPNSSTAAKSFEDLTDHPVTRSEKAASFKLQRQNRVDSKETEC 2M2F Disintegrin and metalloproteinase do