BindingDB Reactant_set_id Ligand SMILES Ligand InChI Ligand InChI Key BindingDB MonomerID BindingDB Ligand Name Target Name Target Source Organism According to Curator or DataSource Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) kon (M-1-s-1) koff (s-1) pH Temp (C) Curation/DataSource Article DOI BindingDB Entry DOI PMID PubChem AID Patent Number Authors Institution Link to Ligand in BindingDB Link to Target in BindingDB Link to Ligand-Target Pair in BindingDB Ligand HET ID in PDB PDB ID(s) for Ligand-Target Complex PubChem CID of Ligand PubChem SID of Ligand ChEBI ID of Ligand ChEMBL ID of Ligand DrugBank ID of Ligand IUPHAR_GRAC ID of Ligand KEGG ID of Ligand ZINC ID of Ligand Number of Protein Chains in Target (>1 implies a multichain complex) BindingDB Target Chain Sequence PDB ID(s) of Target Chain UniProt (SwissProt) Recommended Name of Target Chain UniProt (SwissProt) Entry Name of Target Chain UniProt (SwissProt) Primary ID of Target Chain UniProt (SwissProt) Secondary ID(s) of Target Chain UniProt (SwissProt) Alternative ID(s) of Target Chain UniProt (TrEMBL) Submitted Name of Target Chain UniProt (TrEMBL) Entry Name of Target Chain UniProt (TrEMBL) Primary ID of Target Chain UniProt (TrEMBL) Secondary ID(s) of Target Chain UniProt (TrEMBL) Alternative ID(s) of Target Chain 44473 OS([O-])(=O)=c1ccc2[nH+]c(=O)\c(=N/Nc3ccccc3[N+]([O-])=O)c2c1 InChI=1S/C14H10N4O6S/c19-14-13(17-16-11-3-1-2-4-12(11)18(20)21)9-7-8(25(22,23)24)5-6-10(9)15-14/h1-7,16H,(H2,22,23,24)/b17-13- DBZVQMFKEAHTKX-LGMDPLHJSA-N 24531 (3Z)-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonic acid::NSC-117199::NSC117199 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 46800 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24531 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24531&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 91896009 56269483 ZINC13099299 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44474 OC(=O)c1ccc2NC(=O)C(=NNc3ccccc3C(O)=O)c2c1 InChI=1S/C16H11N3O5/c20-14-13(10-7-8(15(21)22)5-6-11(10)17-14)19-18-12-4-2-1-3-9(12)16(23)24/h1-7,18H,(H,21,22)(H,23,24)(H,17,19,20) CUGFLOKHGAUBLN-UHFFFAOYSA-N 24533 (3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid::Oxindole scaffold, 14a Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 800 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24533 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24533&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971250 56269484 ZINC40425072 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44475 OC(=O)c1ccc2NC(=O)C(=NNc3cccc(c3)C(O)=O)c2c1 InChI=1S/C16H11N3O5/c20-14-13(11-7-9(16(23)24)4-5-12(11)17-14)19-18-10-3-1-2-8(6-10)15(21)22/h1-7,18H,(H,21,22)(H,23,24)(H,17,19,20) REBFVIFMSLOFLE-UHFFFAOYSA-N 24534 (3Z)-3-[2-(3-carboxyphenyl)hydrazin-1-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-carboxylic acid::Oxindole scaffold, 14b Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 15800 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24534 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24534&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971251 56269485 ZINC40974622 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44476 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)C(=O)NCc2ccc(Cl)cc2)c1 InChI=1S/C23H17ClN4O4/c24-16-7-4-13(5-8-16)12-25-21(29)14-6-9-19-18(11-14)20(22(30)26-19)28-27-17-3-1-2-15(10-17)23(31)32/h1-11,27H,12H2,(H,25,29)(H,31,32)(H,26,28,30) SFONGWMOKJNSOO-UHFFFAOYSA-N 24535 3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 16 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 22300 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24535 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24535&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971252 56269486 ZINC40974624 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44477 CC(C)NS(=O)(=O)c1ccc2NC(=O)C(=NNc3cccc(c3)C(O)=O)c2c1 InChI=1S/C18H18N4O5S/c1-10(2)22-28(26,27)13-6-7-15-14(9-13)16(17(23)19-15)21-20-12-5-3-4-11(8-12)18(24)25/h3-10,20,22H,1-2H3,(H,24,25)(H,19,21,23) UHEDDJMRJJHKNO-UHFFFAOYSA-N 24536 3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10a Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 4500 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24536 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24536&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971253 56269487 ZINC40975289 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44478 CC(C)NS(=O)(=O)c1ccc2NC(=O)C(=NNc3ccc(cc3)C(O)=O)c2c1 InChI=1S/C18H18N4O5S/c1-10(2)22-28(26,27)13-7-8-15-14(9-13)16(17(23)19-15)21-20-12-5-3-11(4-6-12)18(24)25/h3-10,20,22H,1-2H3,(H,24,25)(H,19,21,23) ZEQXXXUTJHQJPV-UHFFFAOYSA-N 24537 4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10b Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 4500 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24537 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24537&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971254 56269488 ZINC40975291 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44479 NS(=O)(=O)c1ccc2NC(=O)C(=NNc3ccccc3[N+]([O-])=O)c2c1 InChI=1S/C14H11N5O5S/c15-25(23,24)8-5-6-10-9(7-8)13(14(20)16-10)18-17-11-3-1-2-4-12(11)19(21)22/h1-7,17H,(H2,15,23,24)(H,16,18,20) DVBRTLAFUYOZLB-UHFFFAOYSA-N 24538 (3Z)-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide::Oxindole scaffold, 10c Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 11900 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24538 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24538&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971255 56269489 ZINC40834621 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44480 [O-][N+](=O)c1ccccc1NN=C1C(=O)Nc2ccc(cc12)S(=O)(=O)NCc1ccc(Cl)cc1 InChI=1S/C21H16ClN5O5S/c22-14-7-5-13(6-8-14)12-23-33(31,32)15-9-10-17-16(11-15)20(21(28)24-17)26-25-18-3-1-2-4-19(18)27(29)30/h1-11,23,25H,12H2,(H,24,26,28) AVRGOCDNYXWVMM-UHFFFAOYSA-N 24539 (3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide::Oxindole scaffold, 10d Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 4400 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24539 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24539&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971256 56269490 ZINC40424365 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44481 Cc1ccc(CNS(=O)(=O)c2ccc3NC(=O)C(=NNc4cccc(c4)C(O)=O)c3c2)cc1 InChI=1S/C23H20N4O5S/c1-14-5-7-15(8-6-14)13-24-33(31,32)18-9-10-20-19(12-18)21(22(28)25-20)27-26-17-4-2-3-16(11-17)23(29)30/h2-12,24,26H,13H2,1H3,(H,29,30)(H,25,27,28) WRQDXFZZWXWYFK-UHFFFAOYSA-N 24540 3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10e Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 5000 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24540 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24540&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971257 56269491 ZINC40425173 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44482 OC(=O)c1ccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccccc2)cc1 InChI=1S/C22H18N4O5S/c27-21-20(26-25-16-8-6-15(7-9-16)22(28)29)18-12-17(10-11-19(18)24-21)32(30,31)23-13-14-4-2-1-3-5-14/h1-12,23,25H,13H2,(H,28,29)(H,24,26,27) UHUQVKYMAAMVNN-UHFFFAOYSA-N 24541 4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10f Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 1300 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24541 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24541&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971258 56269492 ZINC40980226 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44483 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2cccc(Cl)c2)c1 InChI=1S/C22H17ClN4O5S/c23-15-5-1-3-13(9-15)12-24-33(31,32)17-7-8-19-18(11-17)20(21(28)25-19)27-26-16-6-2-4-14(10-16)22(29)30/h1-11,24,26H,12H2,(H,29,30)(H,25,27,28) VWMZDCPNRXSTKQ-UHFFFAOYSA-N 24542 3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10g Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 3800 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24542 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24542&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971259 56269493 ZINC40980228 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44484 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(Cl)cc2)c1 InChI=1S/C22H17ClN4O5S/c23-15-6-4-13(5-7-15)12-24-33(31,32)17-8-9-19-18(11-17)20(21(28)25-19)27-26-16-3-1-2-14(10-16)22(29)30/h1-11,24,26H,12H2,(H,29,30)(H,25,27,28) BGWIPJLWWIUCRL-UHFFFAOYSA-N 24543 3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10h Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 1400 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24543 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24543&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971260 56269494 ZINC40979992 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44485 OC(=O)c1ccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(Cl)cc2)cc1 InChI=1S/C22H17ClN4O5S/c23-15-5-1-13(2-6-15)12-24-33(31,32)17-9-10-19-18(11-17)20(21(28)25-19)27-26-16-7-3-14(4-8-16)22(29)30/h1-11,24,26H,12H2,(H,29,30)(H,25,27,28) GKKSQUYQCFCXJQ-UHFFFAOYSA-N 24544 4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10i Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 5900 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24544 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24544&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971261 56269495 ZINC40428996 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44486 OC(=O)c1ccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccccc2Cl)cc1 InChI=1S/C22H17ClN4O5S/c23-18-4-2-1-3-14(18)12-24-33(31,32)16-9-10-19-17(11-16)20(21(28)25-19)27-26-15-7-5-13(6-8-15)22(29)30/h1-11,24,26H,12H2,(H,29,30)(H,25,27,28) NNCLDJYKDAGUFL-UHFFFAOYSA-N 24545 4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10j Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 7400 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24545 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24545&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971262 56269496 ZINC40424207 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44487 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccccc2Cl)c1 InChI=1S/C22H17ClN4O5S/c23-18-7-2-1-4-14(18)12-24-33(31,32)16-8-9-19-17(11-16)20(21(28)25-19)27-26-15-6-3-5-13(10-15)22(29)30/h1-11,24,26H,12H2,(H,29,30)(H,25,27,28) SCQIMLUPUGVXDD-UHFFFAOYSA-N 24546 3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10k Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 5500 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24546 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24546&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971263 56269497 ZINC40979980 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44488 OC(=O)c1ccccc1NN=C1C(=O)Nc2ccc(cc12)S(=O)(=O)NCc1ccc(Cl)c(c1)C(F)(F)F InChI=1S/C23H16ClF3N4O5S/c24-17-7-5-12(9-16(17)23(25,26)27)11-28-37(35,36)13-6-8-18-15(10-13)20(21(32)29-18)31-30-19-4-2-1-3-14(19)22(33)34/h1-10,28,30H,11H2,(H,33,34)(H,29,31,32) MOCRGBDKBGUDGC-UHFFFAOYSA-N 24547 2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl]methyl}sulfamoyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10l Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 22900 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24547 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24547&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971264 56269498 ZINC42920155 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44489 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(F)cc2)c1 InChI=1S/C22H17FN4O5S/c23-15-6-4-13(5-7-15)12-24-33(31,32)17-8-9-19-18(11-17)20(21(28)25-19)27-26-16-3-1-2-14(10-16)22(29)30/h1-11,24,26H,12H2,(H,29,30)(H,25,27,28) ABVSYWGFUNXYAC-UHFFFAOYSA-N 24548 3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10m Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 1000 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24548 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24548&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971265 56269499 ZINC40980202 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44490 OC(=O)c1ccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(F)cc2)cc1 InChI=1S/C22H17FN4O5S/c23-15-5-1-13(2-6-15)12-24-33(31,32)17-9-10-19-18(11-17)20(21(28)25-19)27-26-16-7-3-14(4-8-16)22(29)30/h1-11,24,26H,12H2,(H,29,30)(H,25,27,28) DKJVMTDWMHMIDC-UHFFFAOYSA-N 24549 4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10n Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 6300 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24549 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24549&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971266 56269500 ZINC40424764 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44491 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(F)c(Cl)c2)c1 InChI=1S/C22H16ClFN4O5S/c23-17-8-12(4-6-18(17)24)11-25-34(32,33)15-5-7-19-16(10-15)20(21(29)26-19)28-27-14-3-1-2-13(9-14)22(30)31/h1-10,25,27H,11H2,(H,30,31)(H,26,28,29) LFNWLAPCMNMILF-UHFFFAOYSA-N 24550 3-{2-[(3Z)-5-{[(3-chloro-4-fluorophenyl)methyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10o Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 4800 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24550 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24550&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971267 56269501 ZINC40980204 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44492 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCCc2ccc(Cl)cc2Cl)c1 InChI=1S/C23H18Cl2N4O5S/c24-15-5-4-13(19(25)11-15)8-9-26-35(33,34)17-6-7-20-18(12-17)21(22(30)27-20)29-28-16-3-1-2-14(10-16)23(31)32/h1-7,10-12,26,28H,8-9H2,(H,31,32)(H,27,29,30) PNKGHZHTFNVNJN-UHFFFAOYSA-N 24551 3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10p Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 5200 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24551 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24551&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971268 56269502 ZINC42806607 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44493 OC(=O)c1ccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(Cl)c(c2)C(F)(F)F)cc1 InChI=1S/C23H16ClF3N4O5S/c24-18-7-1-12(9-17(18)23(25,26)27)11-28-37(35,36)15-6-8-19-16(10-15)20(21(32)29-19)31-30-14-4-2-13(3-5-14)22(33)34/h1-10,28,30H,11H2,(H,33,34)(H,29,31,32) VAMIHNZRXGILMF-UHFFFAOYSA-N 24552 4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl]methyl}sulfamoyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10q Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 8300 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24552 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24552&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971269 56269503 ZINC49888655 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 44494 OC(=O)c1cccc(NN=C2C(=O)Nc3ccc(cc23)S(=O)(=O)NCc2ccc(Cl)c(c2)C(F)(F)F)c1 InChI=1S/C23H16ClF3N4O5S/c24-18-6-4-12(8-17(18)23(25,26)27)11-28-37(35,36)15-5-7-19-16(10-15)20(21(32)29-19)31-30-14-3-1-2-13(9-14)22(33)34/h1-10,28,30H,11H2,(H,33,34)(H,29,31,32) FLSQMBDKSLKOPK-UHFFFAOYSA-N 24553 3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl]methyl}sulfamoyl)-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid::Oxindole scaffold, 10r Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 10600 7 22.00 C Curated from the literature by BindingDB 10.1021/jm8002526 10.7270/Q2XD0ZZ8 18680359 aid1798441 Lawrence, HR; Pireddu, R; Chen, L; Luo, Y; Sung, SS; Szymanski, AM; Yip, ML; Guida, WC; Sebti, SM; Wu, J; Lawrence, NJ Moffitt Cancer Center http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24553 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24553&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 24971270 56269504 ZINC49888752 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45522 OC(=O)\C=C\c1ccc(c(Cl)c1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2 InChI=1S/C25H25ClO3/c26-22-10-15(2-6-24(28)29)1-4-20(22)19-3-5-23(27)21(11-19)25-12-16-7-17(13-25)9-18(8-16)14-25/h1-6,10-11,16-18,27H,7-9,12-14H2,(H,28,29)/b6-2+ ZUIMAMHUQKPCBR-QHHAFSJGSA-N 25122 (2E)-3-{4-[3-(adamantan-1-yl)-4-hydroxyphenyl]-3-chlorophenyl}prop-2-enoic acid::(E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid::3-Cl-AHPC Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 2100 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25122 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25122&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 9866186 56374264 ZINC03816491 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45523 CC(=O)Nc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C27H28ClNO3/c1-16(30)29-25-6-4-21(22-5-2-17(11-24(22)28)3-7-26(31)32)12-23(25)27-13-18-8-19(14-27)10-20(9-18)15-27/h2-7,11-12,18-20H,8-10,13-15H2,1H3,(H,29,30)(H,31,32)/b7-3+ WAHJESODRLFYLI-XVNBXDOJSA-N 25123 (2E)-3-{4-[3-(adamantan-1-yl)-4-acetamidophenyl]-3-chlorophenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 2 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 4550 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25123 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25123&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 25023777 56374265 ZINC40393710 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45524 Nc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C25H26ClNO2/c26-22-10-15(2-6-24(28)29)1-4-20(22)19-3-5-23(27)21(11-19)25-12-16-7-17(13-25)9-18(8-16)14-25/h1-6,10-11,16-18H,7-9,12-14,27H2,(H,28,29)/b6-2+ MDZHCLVOVABFGD-QHHAFSJGSA-N 25124 (2E)-3-{4-[3-(adamantan-1-yl)-4-aminophenyl]-3-chlorophenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 3 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 1830 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25124 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25124&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 25023778 56374266 ZINC40874312 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45525 OC(=O)\C=C\c1ccc(c(Cl)c1)-c1ccc(F)c(c1)C12CC3CC(CC(C3)C1)C2 InChI=1S/C25H24ClFO2/c26-22-10-15(2-6-24(28)29)1-4-20(22)19-3-5-23(27)21(11-19)25-12-16-7-17(13-25)9-18(8-16)14-25/h1-6,10-11,16-18H,7-9,12-14H2,(H,28,29)/b6-2+ PMDPBRYUGWJNJE-QHHAFSJGSA-N 25125 (2E)-3-{4-[3-(adamantan-1-yl)-4-fluorophenyl]-3-chlorophenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 4 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 2110 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25125 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25125&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 25023779 56374267 ZINC40393508 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45526 OC(=O)\C=C\c1ccc(c(Cl)c1)-c1ccc(F)cc1 InChI=1S/C15H10ClFO2/c16-14-9-10(2-8-15(18)19)1-7-13(14)11-3-5-12(17)6-4-11/h1-9H,(H,18,19)/b8-2+ FDYYVCWZNRFURU-KRXBUXKQSA-N 25126 (2E)-3-[3-chloro-4-(4-fluorophenyl)phenyl]prop-2-enoic acid::3-Cl-AHPC analogue, 5 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 500000 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25126 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25126&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 25023780 56374268 ZINC40862402 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45527 CC(C)(C)C#Cc1cc(ccc1O)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C21H19ClO3/c1-21(2,3)11-10-16-13-15(6-8-19(16)23)17-7-4-14(12-18(17)22)5-9-20(24)25/h4-9,12-13,23H,1-3H3,(H,24,25)/b9-5+ VWCJLBHQLMBOFA-WEVVVXLNSA-N 25127 (2E)-3-{3-chloro-4-[3-(3,3-dimethylbut-1-yn-1-yl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 6 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 450 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25127 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25127&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 23577109 56374269 ZINC40862712 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45528 Cc1cccc(C)c1-c1cc(ccc1O)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C23H19ClO3/c1-14-4-3-5-15(2)23(14)19-13-17(8-10-21(19)25)18-9-6-16(12-20(18)24)7-11-22(26)27/h3-13,25H,1-2H3,(H,26,27)/b11-7+ JXUBWICOZTWTTM-YRNVUSSQSA-N 25128 (2E)-3-{3-chloro-4-[3-(2,6-dimethylphenyl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 7 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 19900 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25128 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25128&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 23577108 56374270 ZINC40393604 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45529 OC(=O)\C=C\c1ccc(c(Cl)c1)-c1ccc(O)c(c1)C12CC3CC1CC(C2)C3 InChI=1S/C24H23ClO3/c25-21-10-14(2-6-23(27)28)1-4-19(21)17-3-5-22(26)20(11-17)24-12-15-7-16(13-24)9-18(24)8-15/h1-6,10-11,15-16,18,26H,7-9,12-13H2,(H,27,28)/b6-2+ VJTNQFZAJSEDRX-QHHAFSJGSA-N 25129 (2E)-3-[3-chloro-4-(4-hydroxy-3-{tricyclo[3.3.1.0^{3,7}]nonan-3-yl}phenyl)phenyl]prop-2-enoic acid::3-Cl-AHPC analogue, 8 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 3910 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25129 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25129&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 25023781 56374271 ZINC40862714 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45530 CC1(CCCCC1)c1cc(ccc1O)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C22H23ClO3/c1-22(11-3-2-4-12-22)18-14-16(7-9-20(18)24)17-8-5-15(13-19(17)23)6-10-21(25)26/h5-10,13-14,24H,2-4,11-12H2,1H3,(H,25,26)/b10-6+ SPCYQAVBCOCHLI-UXBLZVDNSA-N 25130 (2E)-3-{3-chloro-4-[4-hydroxy-3-(1-methylcyclohexyl)phenyl]phenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 9 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 6400 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25130 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25130&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 25023782 56374272 ZINC40392617 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45531 CC12CC3CC(C)(C1)CC(C3)(C2)c1cc(ccc1O)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C27H29ClO3/c1-25-11-18-12-26(2,14-25)16-27(13-18,15-25)21-10-19(5-7-23(21)29)20-6-3-17(9-22(20)28)4-8-24(30)31/h3-10,18,29H,11-16H2,1-2H3,(H,30,31)/b8-4+ DIXYWCRPNNUEHU-XBXARRHUSA-N 25131 (2E)-3-{3-chloro-4-[3-(3,5-dimethyladamantan-1-yl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 10 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 2270 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25131 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25131&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 23577110 56374273 ZINC40863867 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45532 CC1(SCCCS1)c1cc(ccc1O)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C20H19ClO3S2/c1-20(25-9-2-10-26-20)16-12-14(5-7-18(16)22)15-6-3-13(11-17(15)21)4-8-19(23)24/h3-8,11-12,22H,2,9-10H2,1H3,(H,23,24)/b8-4+ VNFDEGDKIVKVNJ-XBXARRHUSA-N 25132 (2E)-3-{3-chloro-4-[4-hydroxy-3-(2-methyl-1,3-dithian-2-yl)phenyl]phenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 11 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 10200 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25132 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25132&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 25023783 56374274 ZINC40392943 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7 45533 CCC(CC)(CC)c1cc(ccc1O)-c1ccc(\C=C\C(O)=O)cc1Cl InChI=1S/C22H25ClO3/c1-4-22(5-2,6-3)18-14-16(9-11-20(18)24)17-10-7-15(13-19(17)23)8-12-21(25)26/h7-14,24H,4-6H2,1-3H3,(H,25,26)/b12-8+ APBISRKAAZZLPB-XYOKQWHBSA-N 25133 (2E)-3-{3-chloro-4-[3-(3-ethylpentan-3-yl)-4-hydroxyphenyl]phenyl}prop-2-enoic acid::3-Cl-AHPC analogue, 12 Tyrosine-protein phosphatase non-receptor type 11 [205-593] Homo sapiens 5370 6 30.00 C Curated from the literature by BindingDB 10.1021/jm800456k 10.7270/Q24T6GNQ 18759424 aid1798517 Dawson, MI; Xia, Z; Jiang, T; Ye, M; Fontana, JA; Farhana, L; Patel, B; Xue, LP; Bhuiyan, M; Pellicciari, R; Macchiarulo, A; Nuti, R; Zhang, XK; Han, YH; Tautz, L; Hobbs, PD; Jong, L; Waleh, N; Chao, WR; Feng, GS; Pang, Y; Su, Y Burnham Institute for Medical Research http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25133 http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=2620&target=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25133&enzyme=Tyrosine-protein+phosphatase+non-receptor+type+11+%5B205-593%5D&column=ki&startPg=0&Increment=50&submit=Search 23577107 56374275 ZINC40864884 1 TLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEPVSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEVERGKSKCVKYWPDEYALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVWQYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILIDIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSKRKGHEYTNIKYSLADQTSGDQSPLPPCTPTPPCAEMREDSARVYENVGLMQQQ 3B7O Tyrosine-protein phosphatase non-receptor type 11 PTN11_HUMAN Q06124 A8K1D9 Q96HD7