BindingDB Reactant_set_id	Ligand SMILES	Ligand InChI	Ligand InChI Key	BindingDB MonomerID	BindingDB Ligand Name	Target Name	Target Source Organism According to Curator or DataSource	Ki (nM)	IC50 (nM)	Kd (nM)	EC50 (nM)	kon (M-1-s-1)	koff (s-1)	pH	Temp (C)	Curation/DataSource	Article DOI	BindingDB Entry DOI	PMID	PubChem AID	Patent Number	Authors	Institution	Link to Ligand in BindingDB	Link to Target in BindingDB	Link to Ligand-Target Pair in BindingDB	Ligand HET ID in PDB	PDB ID(s) for Ligand-Target Complex	PubChem CID of Ligand	PubChem SID of Ligand	ChEBI ID of Ligand	ChEMBL ID of Ligand	DrugBank ID of Ligand	IUPHAR_GRAC ID of Ligand	KEGG ID of Ligand	ZINC ID of Ligand	Number of Protein Chains in Target (>1 implies a multichain complex)	BindingDB Target Chain Sequence	PDB ID(s) of Target Chain	UniProt (SwissProt) Recommended Name of Target Chain	UniProt (SwissProt) Entry Name of Target Chain	UniProt (SwissProt) Primary ID of Target Chain	UniProt (SwissProt) Secondary ID(s) of Target Chain	UniProt (SwissProt) Alternative ID(s) of Target Chain	UniProt (TrEMBL) Submitted Name of Target Chain	UniProt (TrEMBL) Entry Name of Target Chain	UniProt (TrEMBL) Primary ID of Target Chain	UniProt (TrEMBL) Secondary ID(s) of Target Chain	UniProt (TrEMBL) Alternative ID(s) of Target Chain
51056788	CN1C[C@H](Cc2ccccn2)C(=O)C(C1)=Cc1ccccn1	InChI=1S/C18H19N3O/c1-21-12-14(10-16-6-2-4-8-19-16)18(22)15(13-21)11-17-7-3-5-9-20-17/h2-10,15H,11-13H2,1H3/t15-/m0/s1	XNBNPTNODRUPCB-HNNXBMFYSA-N	50431025	CHEMBL2338335	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm4002692	10.7270/Q2SB473Z	23550937			Brown, A; Shi, Q; Moore, TW; Yoon, Y; Prussia, A; Maddox, C; Liotta, DC; Shim, H; Snyder, JP	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431025	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431025&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71720141	164159900		CHEMBL2338335				ZINC95586371	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51056800	CN1C[C@@H](Cc2ccccn2)C(=O)C(C1)=Cc1ccccn1	InChI=1S/C18H19N3O/c1-21-12-14(10-16-6-2-4-8-19-16)18(22)15(13-21)11-17-7-3-5-9-20-17/h2-10,15H,11-13H2,1H3/t15-/m1/s1	XNBNPTNODRUPCB-OAHLLOKOSA-N	50431026	CHEMBL2338334	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm4002692	10.7270/Q2SB473Z	23550937			Brown, A; Shi, Q; Moore, TW; Yoon, Y; Prussia, A; Maddox, C; Liotta, DC; Shim, H; Snyder, JP	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431026	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431026&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71718330	164159901		CHEMBL2338334				ZINC95591932	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51056812	O=C1\C(CSC\C1=C/c1ccccn1)=C\c1ccccn1	InChI=1S/C17H14N2OS/c20-17-13(9-15-5-1-3-7-18-15)11-21-12-14(17)10-16-6-2-4-8-19-16/h1-10H,11-12H2/b13-9+,14-10+	SZUIRPWFHMMLIA-UTLPMFLDSA-N	50431027	CHEMBL2036343	MAP kinase-activated protein kinase 2	Homo sapiens		 16000							ChEMBL	10.1021/jm4002692	10.7270/Q2SB473Z	23550937			Brown, A; Shi, Q; Moore, TW; Yoon, Y; Prussia, A; Maddox, C; Liotta, DC; Shim, H; Snyder, JP	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431027&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56832546	164159902		CHEMBL2036343				ZINC84728698	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51056824	CN1C\C(=C/c2ccccn2)C(=O)\C(C1)=C\c1ccccn1	InChI=1S/C18H17N3O/c1-21-12-14(10-16-6-2-4-8-19-16)18(22)15(13-21)11-17-7-3-5-9-20-17/h2-11H,12-13H2,1H3/b14-10+,15-11+	VCLPNFMJSSBBKX-WFYKWJGLSA-N	50431028	CHEMBL2338333	MAP kinase-activated protein kinase 2	Homo sapiens		 9800							ChEMBL	10.1021/jm4002692	10.7270/Q2SB473Z	23550937			Brown, A; Shi, Q; Moore, TW; Yoon, Y; Prussia, A; Maddox, C; Liotta, DC; Shim, H; Snyder, JP	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431028&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			2132479	164159903		CHEMBL2338333				ZINC33340364	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51056836	O=C1\C(CNC\C1=C/c1ccccn1)=C\c1ccccn1	InChI=1S/C17H15N3O/c21-17-13(9-15-5-1-3-7-19-15)11-18-12-14(17)10-16-6-2-4-8-20-16/h1-10,18H,11-12H2/b13-9+,14-10+	GXFKPANENAOEOK-UTLPMFLDSA-N	50431029	CHEMBL574646	MAP kinase-activated protein kinase 2	Homo sapiens		 6700							ChEMBL	10.1021/jm4002692	10.7270/Q2SB473Z	23550937			Brown, A; Shi, Q; Moore, TW; Yoon, Y; Prussia, A; Maddox, C; Liotta, DC; Shim, H; Snyder, JP	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431029&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16079040	164159904		CHEMBL574646				ZINC35000883	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51056848	Fc1ccccc1\C=C1/CNC\C(=C/c2ccccc2F)C1=O	InChI=1S/C19H15F2NO/c20-17-7-3-1-5-13(17)9-15-11-22-12-16(19(15)23)10-14-6-2-4-8-18(14)21/h1-10,22H,11-12H2/b15-9+,16-10+	NIVYQYSNRUIFIF-KAVGSWPWSA-N	50431030	CHEMBL379849	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm4002692	10.7270/Q2SB473Z	23550937			Brown, A; Shi, Q; Moore, TW; Yoon, Y; Prussia, A; Maddox, C; Liotta, DC; Shim, H; Snyder, JP	Emory University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50431030	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50431030&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9885748	164159905		CHEMBL379849				ZINC34009101	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51057706	CNc1nc(C)c(s1)-c1nc(Nc2cccc(c2)N2CCCNCC2)ncc1C#N	InChI=1S/C21H24N8S/c1-14-19(30-21(23-2)26-14)18-15(12-22)13-25-20(28-18)27-16-5-3-6-17(11-16)29-9-4-7-24-8-10-29/h3,5-6,11,13,24H,4,7-10H2,1-2H3,(H,23,26)(H,25,27,28)	BKOYUSKBPMSUBK-UHFFFAOYSA-N	50425008	CHEMBL2312185	MAP kinase-activated protein kinase 2	Homo sapiens		>5000							ChEMBL	10.1021/jm301475f	10.7270/Q26D5VBB	23301767			Shao, H; Shi, S; Huang, S; Hole, AJ; Abbas, AY; Baumli, S; Liu, X; Lam, F; Foley, DW; Fischer, PM; Noble, M; Endicott, JA; Pepper, C; Wang, S	University of Nottingham	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425008&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	T3C	4BCP,4BCG	71300299	164153883		CHEMBL2312185				ZINC95597277	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55040	Fc1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1	InChI=1S/C17H11FN4O/c18-12-3-1-10(2-4-12)14-7-11(5-6-19-14)15-8-13-16(22-15)20-9-21-17(13)23/h1-9H,(H2,20,21,22,23)	RXGFMJRWVVXOQS-UHFFFAOYSA-N	30309	Pyrrolo-pyrimidone, 2	MAP kinase-activated protein kinase 2	Homo sapiens		 1300					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30309&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119153	85148069						ZINC35285995	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55041	Fc1cccc(c1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1	InChI=1S/C17H11FN4O/c18-12-3-1-2-10(6-12)14-7-11(4-5-19-14)15-8-13-16(22-15)20-9-21-17(13)23/h1-9H,(H2,20,21,22,23)	MRYUNVHMZVASDV-UHFFFAOYSA-N	30310	Pyrrolo-pyrimidone, 3	MAP kinase-activated protein kinase 2	Homo sapiens		 1230					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30310&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119198	85148070						ZINC35286116	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55042	COc1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1	InChI=1S/C18H14N4O2/c1-24-13-4-2-11(3-5-13)15-8-12(6-7-19-15)16-9-14-17(22-16)20-10-21-18(14)23/h2-10H,1H3,(H2,20,21,22,23)	SMKRVAGTVDEXFZ-UHFFFAOYSA-N	30311	Pyrrolo-pyrimidone, 4	MAP kinase-activated protein kinase 2	Homo sapiens		 550					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30311&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44143569	85148071						ZINC40860547	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55043	COc1cccc(c1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1	InChI=1S/C18H14N4O2/c1-24-13-4-2-3-11(7-13)15-8-12(5-6-19-15)16-9-14-17(22-16)20-10-21-18(14)23/h2-10H,1H3,(H2,20,21,22,23)	GARQBBNLFNDLEJ-UHFFFAOYSA-N	30312	Pyrrolo-pyrimidone, 5	MAP kinase-activated protein kinase 2	Homo sapiens		 5200					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30312&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44143570	85148072						ZINC40379035	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55044	O=c1[nH]cnc2[nH]c(cc12)-c1ccnc(c1)-c1ccc(CN2CCOCC2)cc1	InChI=1S/C22H21N5O2/c28-22-18-12-20(26-21(18)24-14-25-22)17-5-6-23-19(11-17)16-3-1-15(2-4-16)13-27-7-9-29-10-8-27/h1-6,11-12,14H,7-10,13H2,(H2,24,25,26,28)	XZRFKEAJVYSCFA-UHFFFAOYSA-N	30313	Pyrrolo-pyrimidone, 6	MAP kinase-activated protein kinase 2	Homo sapiens		 1450					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30313&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119200	85148073						ZINC35286121	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55045	O=C(NC1CCCC1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1	InChI=1S/C23H21N5O2/c29-22(27-17-3-1-2-4-17)15-7-5-14(6-8-15)19-11-16(9-10-24-19)20-12-18-21(28-20)25-13-26-23(18)30/h5-13,17H,1-4H2,(H,27,29)(H2,25,26,28,30)	QMMSIZWXVQDHQO-UHFFFAOYSA-N	30314	Pyrrolo-pyrimidone, 7	MAP kinase-activated protein kinase 2	Homo sapiens		 190					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30314	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30314&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119303	85148074						ZINC35297480	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55046	O=c1[nH]cnc2[nH]c(cc12)-c1ccnc(C=Cc2ccccc2)c1	InChI=1S/C19H14N4O/c24-19-16-11-17(23-18(16)21-12-22-19)14-8-9-20-15(10-14)7-6-13-4-2-1-3-5-13/h1-12H,(H2,21,22,23,24)	OKXVXSCOVXIJDR-UHFFFAOYSA-N	30315	Pyrrolo-pyrimidone, 8	MAP kinase-activated protein kinase 2	Homo sapiens		 170					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30315	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30315&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16042899	85148075						ZINC34886272	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55047	Fc1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1	InChI=1S/C19H13FN4O/c20-14-4-1-12(2-5-14)3-6-15-9-13(7-8-21-15)17-10-16-18(24-17)22-11-23-19(16)25/h1-11H,(H2,22,23,24,25)	MQODTFJRZZFYAA-UHFFFAOYSA-N	30316	Pyrrolo-pyrimidone, 9	MAP kinase-activated protein kinase 2	Homo sapiens		 200					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30316&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119201	85148076						ZINC35286124	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55048	Nc1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1	InChI=1S/C19H15N5O/c20-19-23-17-15(18(25)24-19)11-16(22-17)13-8-9-21-14(10-13)7-6-12-4-2-1-3-5-12/h1-11H,(H4,20,22,23,24,25)	WWABKUDURCHTAK-UHFFFAOYSA-N	30317	Pyrrolo-pyrimidone, 10	MAP kinase-activated protein kinase 2	Homo sapiens		 290					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30317	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30317&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119154	85148077							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55049	FC(F)(F)c1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1	InChI=1S/C20H13F3N4O/c21-20(22,23)19-26-17-15(18(28)27-19)11-16(25-17)13-8-9-24-14(10-13)7-6-12-4-2-1-3-5-12/h1-11H,(H2,25,26,27,28)	LEPAAQFCJAVEQX-UHFFFAOYSA-N	30318	Pyrrolo-pyrimidone, 11	MAP kinase-activated protein kinase 2	Homo sapiens		 1700					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30318	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30318&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119155	85148078						ZINC35286001	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55050	Cc1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1	InChI=1S/C20H16N4O/c1-13-22-19-17(20(25)23-13)12-18(24-19)15-9-10-21-16(11-15)8-7-14-5-3-2-4-6-14/h2-12H,1H3,(H2,22,23,24,25)	LPNYKAPKBFXENX-UHFFFAOYSA-N	30319	Pyrrolo-pyrimidone, 12	MAP kinase-activated protein kinase 2	Homo sapiens		 350					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30319	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30319&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119199	85148079							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55051	CCCCc1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1	InChI=1S/C23H22N4O/c1-2-3-9-21-26-22-19(23(28)27-21)15-20(25-22)17-12-13-24-18(14-17)11-10-16-7-5-4-6-8-16/h4-8,10-15H,2-3,9H2,1H3,(H2,25,26,27,28)	IBFWFBBMKHKMIA-UHFFFAOYSA-N	30320	Pyrrolo-pyrimidone, 13	MAP kinase-activated protein kinase 2	Homo sapiens		 1260					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30320	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30320&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119297	85148080							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55052	O=c1[nH]c(Cc2ccccc2)nc2[nH]c(cc12)-c1ccnc(C=Cc2ccccc2)c1	InChI=1S/C26H20N4O/c31-26-22-17-23(28-25(22)29-24(30-26)15-19-9-5-2-6-10-19)20-13-14-27-21(16-20)12-11-18-7-3-1-4-8-18/h1-14,16-17H,15H2,(H2,28,29,30,31)	BUNJRVUMXKHWBD-UHFFFAOYSA-N	30321	Pyrrolo-pyrimidone, 14	MAP kinase-activated protein kinase 2	Homo sapiens		 340					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30321	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30321&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119298	85148081							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55053	O=C(N1CCOCC1)c1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1	InChI=1S/C24H21N5O3/c30-23-20-14-21(28-22(20)26-15-27-23)18-7-8-25-19(13-18)6-3-16-1-4-17(5-2-16)24(31)29-9-11-32-12-10-29/h1-8,13-15H,9-12H2,(H2,26,27,28,30)	DSHFYIZZAXPSDI-UHFFFAOYSA-N	30322	Pyrrolo-pyrimidone, 15	MAP kinase-activated protein kinase 2	Homo sapiens		 42					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30322	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30322&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119158	85148082						ZINC35286011	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55054	O=c1[nH]cnc2[nH]c(cc12)-c1ccnc(C=Cc2ccc(CN3CCOCC3)cc2)c1	InChI=1S/C24H23N5O2/c30-24-21-14-22(28-23(21)26-16-27-24)19-7-8-25-20(13-19)6-5-17-1-3-18(4-2-17)15-29-9-11-31-12-10-29/h1-8,13-14,16H,9-12,15H2,(H2,26,27,28,30)	AWZFCQRICMFIES-UHFFFAOYSA-N	30323	Pyrrolo-pyrimidone, 16	MAP kinase-activated protein kinase 2	Homo sapiens		 51					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30323	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30323&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119710	85148083						ZINC35298570	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55055	CN(C)CCOc1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1	InChI=1S/C23H23N5O2/c1-28(2)11-12-30-19-7-4-16(5-8-19)3-6-18-13-17(9-10-24-18)21-14-20-22(27-21)25-15-26-23(20)29/h3-10,13-15H,11-12H2,1-2H3,(H2,25,26,27,29)	RLAJOHAIIACFAM-UHFFFAOYSA-N	30324	Pyrrolo-pyrimidone, 17	MAP kinase-activated protein kinase 2	Homo sapiens		 82					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30324	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30324&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119021	85148084							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
55056	CCN(CC)Cc1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1	InChI=1S/C24H25N5O/c1-3-29(4-2)15-18-7-5-17(6-8-18)9-10-20-13-19(11-12-25-20)22-14-21-23(28-22)26-16-27-24(21)30/h5-14,16H,3-4,15H2,1-2H3,(H2,26,27,28,30)	KQJAABRPYRXXCA-UHFFFAOYSA-N	30325	Pyrrolo-pyrimidone, 18	MAP kinase-activated protein kinase 2	Homo sapiens		 150					7.5	22.00 C	Curated from the literature by BindingDB	10.1016/j.bmcl.2008.10.039	10.7270/Q2V40SKW	18945615	aid1799079		Schlapbach, A; Feifel, R; Hawtin, S; Heng, R; Koch, G; Moebitz, H; Revesz, L; Scheufler, C; Velcicky, J; Waelchli, R; Huppertz, C	Novartis	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30325	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30325&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16119156	85148085						ZINC35286004	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54885	O=C1NCCc2[nH]c(cc12)-c1ccncc1	InChI=1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)	DKXHSOUZPMHNIZ-UHFFFAOYSA-N	27344	2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::JMC502647 Compound 8::Pyrrolopyridinone, 1	MAP kinase-activated protein kinase 2	Homo sapiens		 171					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27344&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	0SY	4F9B	11715767	57299053						ZINC16052718	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54886	Clc1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C12H10ClN3O/c13-11-5-7(1-3-14-11)10-6-8-9(16-10)2-4-15-12(8)17/h1,3,5-6,16H,2,4H2,(H,15,17)	JTRXEPCDEVNYPE-UHFFFAOYSA-N	27388	2-(2-chloropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::JMC502647 Compound 7::pyrrolopyridinone scaffold, 10	MAP kinase-activated protein kinase 2	Homo sapiens		 608					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27388&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720432	57299097						ZINC28645388	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54887	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccccc1	InChI=1S/C18H15N3O/c22-18-14-11-17(21-15(14)7-9-20-18)13-6-8-19-16(10-13)12-4-2-1-3-5-12/h1-6,8,10-11,21H,7,9H2,(H,20,22)	NNQMSHWOTYMSDC-UHFFFAOYSA-N	30178	Pyrrolopyridine, 9	MAP kinase-activated protein kinase 2	Homo sapiens		 66					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30178&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719862	85147938						ZINC28645391	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54888	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccncc1	InChI=1S/C17H14N4O/c22-17-13-10-16(21-14(13)4-8-20-17)12-3-7-19-15(9-12)11-1-5-18-6-2-11/h1-3,5-7,9-10,21H,4,8H2,(H,20,22)	OYHOUOHQITXKKO-UHFFFAOYSA-N	30179	Pyrrolopyridine, 10	MAP kinase-activated protein kinase 2	Homo sapiens		 56					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30179&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719968	85147939						ZINC28645394	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54889	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cccnc1	InChI=1S/C17H14N4O/c22-17-13-9-16(21-14(13)4-7-20-17)11-3-6-19-15(8-11)12-2-1-5-18-10-12/h1-3,5-6,8-10,21H,4,7H2,(H,20,22)	FQYJHZDVUMKRTO-UHFFFAOYSA-N	30180	Pyrrolopyridine, 11	MAP kinase-activated protein kinase 2	Homo sapiens		 48					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30180&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719970	85147940						ZINC28645401	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54890	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cncnc1	InChI=1S/C16H13N5O/c22-16-12-6-15(21-13(12)2-4-20-16)10-1-3-19-14(5-10)11-7-17-9-18-8-11/h1,3,5-9,21H,2,4H2,(H,20,22)	PBXJEGAZNPWTKA-UHFFFAOYSA-N	30181	Pyrrolopyridine, 12	MAP kinase-activated protein kinase 2	Homo sapiens		 83					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30181	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30181&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719971	85147941						ZINC28645408	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54891	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccsc1	InChI=1S/C16H13N3OS/c20-16-12-8-15(19-13(12)2-5-18-16)10-1-4-17-14(7-10)11-3-6-21-9-11/h1,3-4,6-9,19H,2,5H2,(H,18,20)	WZGXWJDLVSXDQC-UHFFFAOYSA-N	30182	Pyrrolopyridine, 13	MAP kinase-activated protein kinase 2	Homo sapiens		 76					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30182	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30182&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719973	85147942						ZINC28645422	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54892	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccc2ccccc2c1	InChI=1S/C22H17N3O/c26-22-18-13-21(25-19(18)8-10-24-22)17-7-9-23-20(12-17)16-6-5-14-3-1-2-4-15(14)11-16/h1-7,9,11-13,25H,8,10H2,(H,24,26)	KFKHBBOHNLPMPG-UHFFFAOYSA-N	30183	Pyrrolopyridine, 14	MAP kinase-activated protein kinase 2	Homo sapiens		 52					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30183	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30183&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719974	85147943						ZINC28645428	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54893	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cc2ccccc2s1	InChI=1S/C20H15N3OS/c24-20-14-11-16(23-15(14)6-8-22-20)12-5-7-21-17(9-12)19-10-13-3-1-2-4-18(13)25-19/h1-5,7,9-11,23H,6,8H2,(H,22,24)	AGSGAJGDMUMJNL-UHFFFAOYSA-N	30184	Pyrrolopyridine, 15	MAP kinase-activated protein kinase 2	Homo sapiens		 30					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30184	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30184&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719976	85147944						ZINC28645433	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54894	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cnc2ccccc2c1	InChI=1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)	OWFLADWRSCINST-UHFFFAOYSA-N	30185	CHEMBL226403::Pyrrolopyridine, 16	MAP kinase-activated protein kinase 2	Homo sapiens		 8.5					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30185&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P4O	2JBP,3GOK,3FHR,2JBO,3R2Y,7NRB	10389239	85147945		CHEMBL226403	DB08358			ZINC16052855	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54895	Oc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H15N3O2/c22-17-4-2-1-3-12(17)16-9-11(5-7-19-16)15-10-13-14(21-15)6-8-20-18(13)23/h1-5,7,9-10,21-22H,6,8H2,(H,20,23)	RXYYYEKFDHPCFL-UHFFFAOYSA-N	30186	Pyrrolopyridine, 17	MAP kinase-activated protein kinase 2	Homo sapiens		 410					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30186&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16719977	85147946						ZINC28645443	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54896	Oc1cccc(c1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H15N3O2/c22-13-3-1-2-11(8-13)16-9-12(4-6-19-16)17-10-14-15(21-17)5-7-20-18(14)23/h1-4,6,8-10,21-22H,5,7H2,(H,20,23)	BEJGBKAIVFARDV-UHFFFAOYSA-N	30187	Pyrrolopyridine, 18	MAP kinase-activated protein kinase 2	Homo sapiens		 25					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30187	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30187&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720087	85147947						ZINC28645445	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54897	Oc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H15N3O2/c22-13-3-1-11(2-4-13)16-9-12(5-7-19-16)17-10-14-15(21-17)6-8-20-18(14)23/h1-5,7,9-10,21-22H,6,8H2,(H,20,23)	QONMAHRQVMDAKC-UHFFFAOYSA-N	30188	Pyrrolopyridine, 19	MAP kinase-activated protein kinase 2	Homo sapiens		 21					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30188	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30188&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720088	85147948						ZINC28645450	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54898	Clc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14ClN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	ZNCHVQUSJFJKLF-UHFFFAOYSA-N	30189	Pyrrolopyridine, 20	MAP kinase-activated protein kinase 2	Homo sapiens		 606					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30189&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720090	85147949						ZINC28645452	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54899	Clc1cccc(c1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14ClN3O/c19-13-3-1-2-11(8-13)16-9-12(4-6-20-16)17-10-14-15(22-17)5-7-21-18(14)23/h1-4,6,8-10,22H,5,7H2,(H,21,23)	PHQASTFACIPPJB-UHFFFAOYSA-N	30190	Pyrrolopyridine, 21	MAP kinase-activated protein kinase 2	Homo sapiens		 37					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30190	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30190&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720091	85147950						ZINC28645458	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54900	Clc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14ClN3O/c19-13-3-1-11(2-4-13)16-9-12(5-7-20-16)17-10-14-15(22-17)6-8-21-18(14)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	FCPSNONAHBIVRE-UHFFFAOYSA-N	30191	Pyrrolopyridine, 22	MAP kinase-activated protein kinase 2	Homo sapiens		 32					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30191	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30191&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720093	85147951						ZINC28645465	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54901	Fc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14FN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	XJJYJNMNYDNXNO-UHFFFAOYSA-N	30192	Pyrrolopyridine, 23	MAP kinase-activated protein kinase 2	Homo sapiens		 126					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30192&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	F10	3FXW,2P3G	11992146	85147952			DB07728			ZINC16052794	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54902	Fc1cccc(c1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14FN3O/c19-13-3-1-2-11(8-13)16-9-12(4-6-20-16)17-10-14-15(22-17)5-7-21-18(14)23/h1-4,6,8-10,22H,5,7H2,(H,21,23)	VPOIDAJRXSIWRX-UHFFFAOYSA-N	30193	Pyrrolopyridine, 24	MAP kinase-activated protein kinase 2	Homo sapiens		 30					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30193	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30193&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720095	85147953						ZINC28645470	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54903	Fc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14FN3O/c19-13-3-1-11(2-4-13)16-9-12(5-7-20-16)17-10-14-15(22-17)6-8-21-18(14)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	ZPNSZNWTUQRDST-UHFFFAOYSA-N	30194	Pyrrolopyridine, 25	MAP kinase-activated protein kinase 2	Homo sapiens		 50					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30194	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30194&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720200	85147954						ZINC28645475	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54904	FC(F)(F)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C19H14F3N3O/c20-19(21,22)13-3-1-11(2-4-13)16-9-12(5-7-23-16)17-10-14-15(25-17)6-8-24-18(14)26/h1-5,7,9-10,25H,6,8H2,(H,24,26)	IQFURFKRHVLOTG-UHFFFAOYSA-N	30195	Pyrrolopyridine, 26	MAP kinase-activated protein kinase 2	Homo sapiens		 71					7.5	30.00 C	Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30195	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30195&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720202	85147955						ZINC28645478	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54915	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccc(cc1)C#N	InChI=1S/C19H14N4O/c20-11-12-1-3-13(4-2-12)17-9-14(5-7-21-17)18-10-15-16(23-18)6-8-22-19(15)24/h1-5,7,9-10,23H,6,8H2,(H,22,24)	FJFQQDIWZQOBLI-UHFFFAOYSA-N	30196	Pyrrolopyridine, 27	MAP kinase-activated protein kinase 2	Homo sapiens		 62							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30196&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720203	85147956						ZINC28645482	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54916	CC(=O)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C20H17N3O2/c1-12(24)13-2-4-14(5-3-13)18-10-15(6-8-21-18)19-11-16-17(23-19)7-9-22-20(16)25/h2-6,8,10-11,23H,7,9H2,1H3,(H,22,25)	NXAVJNAINAJWDN-UHFFFAOYSA-N	30197	Pyrrolopyridine, 28	MAP kinase-activated protein kinase 2	Homo sapiens		 51							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30197	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30197&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720205	85147957						ZINC28645487	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54917	COc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C19H17N3O2/c1-24-14-4-2-12(3-5-14)17-10-13(6-8-20-17)18-11-15-16(22-18)7-9-21-19(15)23/h2-6,8,10-11,22H,7,9H2,1H3,(H,21,23)	IEHGEOSPJOSETA-UHFFFAOYSA-N	30198	Pyrrolopyridine, 29	MAP kinase-activated protein kinase 2	Homo sapiens		 55							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30198	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30198&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720207	85147958						ZINC28645490	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54918	Nc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H16N4O/c19-13-3-1-11(2-4-13)16-9-12(5-7-20-16)17-10-14-15(22-17)6-8-21-18(14)23/h1-5,7,9-10,22H,6,8,19H2,(H,21,23)	OVFRSUMNMCYPAW-UHFFFAOYSA-N	30199	Pyrrolopyridine, 30	MAP kinase-activated protein kinase 2	Homo sapiens		 41							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30199	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30199&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720208	85147959						ZINC28645494	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54919	OC(=O)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C19H15N3O3/c23-18-14-10-17(22-15(14)6-8-21-18)13-5-7-20-16(9-13)11-1-3-12(4-2-11)19(24)25/h1-5,7,9-10,22H,6,8H2,(H,21,23)(H,24,25)	IKGYIULYSDTWTQ-UHFFFAOYSA-N	30200	Pyrrolopyridine, 31	MAP kinase-activated protein kinase 2	Homo sapiens		 22							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30200	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30200&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720315	85147960						ZINC28645500	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54920	O=C(NC1CC1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C22H20N4O2/c27-21(25-16-5-6-16)14-3-1-13(2-4-14)19-11-15(7-9-23-19)20-12-17-18(26-20)8-10-24-22(17)28/h1-4,7,9,11-12,16,26H,5-6,8,10H2,(H,24,28)(H,25,27)	DBTKHUDMVFSPSD-UHFFFAOYSA-N	30201	Pyrrolopyridine, 32	MAP kinase-activated protein kinase 2	Homo sapiens		 15							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30201	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30201&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720316	85147961						ZINC28645503	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54921	O=C(NC1CCCC1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C24H24N4O2/c29-23(27-18-3-1-2-4-18)16-7-5-15(6-8-16)21-13-17(9-11-25-21)22-14-19-20(28-22)10-12-26-24(19)30/h5-9,11,13-14,18,28H,1-4,10,12H2,(H,26,30)(H,27,29)	VZGXJTZKPDEJGJ-UHFFFAOYSA-N	30202	Pyrrolopyridine, 33	MAP kinase-activated protein kinase 2	Homo sapiens		 8							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30202	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30202&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10453611	85147962						ZINC28645506	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54922	O=C(NC1CCCCC1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C25H26N4O2/c30-24(28-19-4-2-1-3-5-19)17-8-6-16(7-9-17)22-14-18(10-12-26-22)23-15-20-21(29-23)11-13-27-25(20)31/h6-10,12,14-15,19,29H,1-5,11,13H2,(H,27,31)(H,28,30)	ZJYOMQSNBGAQNB-UHFFFAOYSA-N	30203	Pyrrolopyridine, 34	MAP kinase-activated protein kinase 2	Homo sapiens		 17							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30203	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30203&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720318	85147963						ZINC28645509	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54923	O=C(NCc1ccccc1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C26H22N4O2/c31-25(29-16-17-4-2-1-3-5-17)19-8-6-18(7-9-19)23-14-20(10-12-27-23)24-15-21-22(30-24)11-13-28-26(21)32/h1-10,12,14-15,30H,11,13,16H2,(H,28,32)(H,29,31)	BUYKQYWJELIXQN-UHFFFAOYSA-N	30204	Pyrrolopyridine, 35	MAP kinase-activated protein kinase 2	Homo sapiens		 8							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30204	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30204&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10007353	85147964						ZINC28645515	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54924	O=C(NCCc1ccccc1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C27H24N4O2/c32-26(29-13-10-18-4-2-1-3-5-18)20-8-6-19(7-9-20)24-16-21(11-14-28-24)25-17-22-23(31-25)12-15-30-27(22)33/h1-9,11,14,16-17,31H,10,12-13,15H2,(H,29,32)(H,30,33)	MFPLVKCDUSQJLT-UHFFFAOYSA-N	30205	Pyrrolopyridine, 36	MAP kinase-activated protein kinase 2	Homo sapiens		 46							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30205	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30205&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720319	85147965						ZINC28645519	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
54925	CN(Cc1ccccc1)C(=O)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C27H24N4O2/c1-31(17-18-5-3-2-4-6-18)27(33)20-9-7-19(8-10-20)24-15-21(11-13-28-24)25-16-22-23(30-25)12-14-29-26(22)32/h2-11,13,15-16,30H,12,14,17H2,1H3,(H,29,32)	UXRPOGJSOJZMFZ-UHFFFAOYSA-N	30206	Pyrrolopyridine, 37	MAP kinase-activated protein kinase 2	Homo sapiens		 56							Curated from the literature by BindingDB	10.1021/jm0611004	10.7270/Q2794313	17480064	aid1799071		Anderson, DR; Meyers, MJ; Vernier, WF; Mahoney, MW; Kurumbail, RG; Caspers, N; Poda, GI; Schindler, JF; Reitz, DB; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30206	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30206&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16720542	85147966						ZINC28645528	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
67238	CN[C@H]1C[C@@H]2O[C@](C)([C@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m0/s1	HKSZLNNOFSGOKW-HMWZOHBLSA-N	31096	CHEMBL290084::Staurosporine::cid_451705	MAP kinase-activated protein kinase 2	Homo sapiens			 880000						PubChem		10.7270/Q2348HR1		aid1433		PubChem, PC	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31096&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			451705	242052841		CHEMBL290084		346		ZINC05615681	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
321193	Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-c1ccnc(n1)C(C)(C)O	InChI=1S/C25H22ClF2N5O3/c1-13-10-30-18(17-5-6-29-24(32-17)25(3,4)35)9-20(13)33-14(2)7-21(22(26)23(33)34)36-12-19-16(28)8-15(27)11-31-19/h5-11,35H,12H2,1-4H3	FQPQMJULRZINPV-UHFFFAOYSA-N	175242	US9115089, 49	MAP kinase-activated protein kinase 2	Homo sapiens		 21					7.5		US Patent		10.7270/Q25M64H1		aid1801515	US9115089	Hockerman, SL; Monahan, JB; Selness, SR	Confluence Life Sciences Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=175242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=175242&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86291496	313044016							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
412032	Nc1ccc(cn1)-c1ccc2ncc3c(n(-c4cccc(c4)C(F)(F)F)c(=O)[nH]c3=O)c2n1	InChI=1S/C22H13F3N6O2/c23-22(24,25)12-2-1-3-13(8-12)31-19-14(20(32)30-21(31)33)10-27-16-6-5-15(29-18(16)19)11-4-7-17(26)28-9-11/h1-10H,(H2,26,28)(H,30,32,33)	OIOOKLQHEDGJOE-UHFFFAOYSA-N	236557	US9365572, 5	MAP kinase-activated protein kinase 2	Homo sapiens		>10000					7.5	28.00 C	US Patent		10.7270/Q20C4TNC		aid1803088	US9365572	Wu, F; Shu, C	Xuanzhu Pharma Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=236557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=236557&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			129012341	340130144							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50072314	CC(C)N1CCN(CC1)C(=O)c1ccc(NC(=O)Nc2ccc(cc2)-c2nc(nc(n2)N2C3CCC2COC3)C2CCOCC2)cc1	InChI=1S/C35H44N8O4/c1-23(2)41-15-17-42(18-16-41)33(44)26-5-9-28(10-6-26)37-35(45)36-27-7-3-24(4-8-27)31-38-32(25-13-19-46-20-14-25)40-34(39-31)43-29-11-12-30(43)22-47-21-29/h3-10,23,25,29-30H,11-22H2,1-2H3,(H2,36,37,45)	QUBPQLLMMSZSGD-UHFFFAOYSA-N	50315069	1-(4-(4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)-6-(tetrahydro-2H-pyran-4-yl)-1,3,5-triazin-2-yl)phenyl)-3-(4-(4-isopropylpiperazine-1-carbonyl)phenyl)urea::CHEMBL1091356	MAP kinase-activated protein kinase 2	Homo sapiens		<50000							ChEMBL	10.1016/j.bmcl.2010.02.031	10.7270/Q2DZ08GK	20223663			Verheijen, JC; Richard, DJ; Curran, K; Kaplan, J; Yu, K; Zask, A	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50315069	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50315069&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46866604	104149430		CHEMBL1091356				ZINC49792996	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50092238	Cc1c(NC(=O)c2ccc(cc2)C(C)(C)C)cccc1-c1nc(Nc2ccc(cc2)C(=O)N2CCOCC2)c2nc[nH]c2n1	InChI=1S/C34H35N7O3/c1-21-26(6-5-7-27(21)38-32(42)22-8-12-24(13-9-22)34(2,3)4)29-39-30-28(35-20-36-30)31(40-29)37-25-14-10-23(11-15-25)33(43)41-16-18-44-19-17-41/h5-15,20H,16-19H2,1-4H3,(H,38,42)(H2,35,36,37,39,40)	IGXJXMLDIIGDNE-UHFFFAOYSA-N	50012060	CHEMBL3263640	MAP kinase-activated protein kinase 2	Homo sapiens		 13330							ChEMBL	10.1016/j.bmcl.2014.02.075	10.7270/Q2K075TC	24685542			Shi, Q; Tebben, A; Dyckman, AJ; Li, H; Liu, C; Lin, J; Spergel, S; Burke, JR; McIntyre, KW; Olini, GC; Strnad, J; Surti, N; Muckelbauer, JK; Chang, C; An, Y; Cheng, L; Ruan, Q; Leftheris, K; Carter, PH; Tino, J; De Lucca, GV	Bristol-Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50012060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50012060&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53356518	242057988		CHEMBL3263640					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50109536	CC(C)(C)CNC(=O)CC1CNC(=O)c2cc(cn12)-c1ccsc1	InChI=1S/C18H23N3O2S/c1-18(2,3)11-20-16(22)7-14-8-19-17(23)15-6-13(9-21(14)15)12-4-5-24-10-12/h4-6,9-10,14H,7-8,11H2,1-3H3,(H,19,23)(H,20,22)	PNMQDIXULZYDDT-UHFFFAOYSA-N	50021626	CHEMBL3298400	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2013.09.054	10.7270/Q23F4R7S	24139169			Casuscelli, F; Ardini, E; Avanzi, N; Casale, E; Cervi, G; D'Anello, M; Donati, D; Faiardi, D; Ferguson, RD; Fogliatto, G; Galvani, A; Marsiglio, A; Mirizzi, DG; Montemartini, M; Orrenius, C; Papeo, G; Piutti, C; Salom, B; Felder, ER	Nerviano Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021626&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	UGX	4BZN	90645194	103932324		CHEMBL3298400				ZINC26498864	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50109538	CN1CCN(C[C@@H](NC(=O)C[C@H]2CNC(=O)c3cc(cn23)-c2cccc(Cl)c2)C2CCCCC2)CC1	InChI=1S/C28H38ClN5O2/c1-32-10-12-33(13-11-32)19-25(20-6-3-2-4-7-20)31-27(35)16-24-17-30-28(36)26-15-22(18-34(24)26)21-8-5-9-23(29)14-21/h5,8-9,14-15,18,20,24-25H,2-4,6-7,10-13,16-17,19H2,1H3,(H,30,36)(H,31,35)/t24-,25+/m0/s1	UKZRGBUTBINTPD-LOSJGSFVSA-N	50021618	CHEMBL3297762::US9145418, 2	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2013.09.054	10.7270/Q23F4R7S	24139169			Casuscelli, F; Ardini, E; Avanzi, N; Casale, E; Cervi, G; D'Anello, M; Donati, D; Faiardi, D; Ferguson, RD; Fogliatto, G; Galvani, A; Marsiglio, A; Mirizzi, DG; Montemartini, M; Orrenius, C; Papeo, G; Piutti, C; Salom, B; Felder, ER	Nerviano Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50021618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50021618&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71547862	103932316		CHEMBL3297762				ZINC26501564	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50152295	O[C@H]1CC[C@@H](CC1)c1[nH]ncc1-c1ccnc(NC2CCCC2)n1	InChI=1S/C18H25N5O/c24-14-7-5-12(6-8-14)17-15(11-20-23-17)16-9-10-19-18(22-16)21-13-3-1-2-4-13/h9-14,24H,1-8H2,(H,20,23)(H,19,21,22)/t12-,14-	JCJAEEODSKNKTC-MQMHXKEQSA-N	50277910	4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyrazol-3-yl)cyclohexanol::CHEMBL507249	MAP kinase-activated protein kinase 2	Homo sapiens		 13000							ChEMBL	10.1016/j.bmcl.2009.03.023	10.7270/Q26H4H9D	19327989			Humphries, PS; Lafontaine, JA; Agree, CS; Alexander, D; Chen, P; Do, QQ; Li, LY; Lunney, EA; Rajapakse, RJ; Siegel, K; Timofeevski, SL; Wang, T; Wilhite, DM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50277910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50277910&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44591740	104120373		CHEMBL507249				ZINC40379254	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50165651	CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1	BMGQWWVMWDBQGC-IIFHNQTCSA-N	50326053	CHEMBL608533::PKC-412	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1182/blood-2009-05-222034	10.7270/Q2PN95V2	19654408			Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326053&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	2K2	4NCT	9829523	123105168	63452	CHEMBL608533					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50166969	C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4C(=O)NCc4c4c5ccccc5n2c4c13	InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1	UIARLYUEJFELEN-LROUJFHJSA-N	50308060	16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaen-3-one::CEP-701::CHEMBL603469::US11370779, Compound CEP-701	MAP kinase-activated protein kinase 2	Homo sapiens			 230						ChEMBL	10.1182/blood-2009-05-222034	10.7270/Q2PN95V2	19654408			Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308060&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	2V9	5WNJ,4OTG	126565	104162421		CHEMBL603469		5672		ZINC03781738	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50181484	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	MAP kinase-activated protein kinase 2	Homo sapiens			 880						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50182717	C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4C(=O)NCc4c4c5ccccc5n2c4c13	InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1	UIARLYUEJFELEN-LROUJFHJSA-N	50308060	16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaen-3-one::CEP-701::CHEMBL603469::US11370779, Compound CEP-701	MAP kinase-activated protein kinase 2	Homo sapiens			 230						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50308060	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50308060&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	2V9	5WNJ,4OTG	126565	104162421		CHEMBL603469		5672		ZINC03781738	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50188381	COC(=O)c1ccc2\C(=C(\Nc3ccc(cc3)N(C)C(=O)CN3CCN(C)CC3)c3ccccc3)C(=O)Nc2c1	InChI=1S/C31H33N5O4/c1-34-15-17-36(18-16-34)20-27(37)35(2)24-12-10-23(11-13-24)32-29(21-7-5-4-6-8-21)28-25-14-9-22(31(39)40-3)19-26(25)33-30(28)38/h4-14,19,32H,15-18,20H2,1-3H3,(H,33,38)/b29-28-	XZXHXSATPCNXJR-ZIADKAODSA-N	50026612	BIBF-1120::Nintedanib::US10981896, Compound Nintedanib::US11046672, Nintedanib::US11208381, Nintedanib::Vargatef	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50026612	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50026612&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	XIN	5MAF,6NEC,3C7Q,5TE0	9809715	277286638							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50181014	CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1	BMGQWWVMWDBQGC-IIFHNQTCSA-N	50326053	CHEMBL608533::PKC-412	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326053&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	2K2	4NCT	9829523	123105168	63452	CHEMBL608533					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50176057	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2CCC(=C)[C@H]1\C=C\C1=CC(=O)OC1O	InChI=1S/C25H36O3/c1-16-7-10-20-24(4,18(16)9-8-17-15-21(26)28-22(17)27)14-11-19-23(2,3)12-6-13-25(19,20)5/h8-9,15,18-20,22,27H,1,6-7,10-14H2,2-5H3/b9-8+/t18-,19+,20+,22?,24+,25+/m1/s1	YFUNKUDHWJXNSX-GSDHUERBSA-N	50269815	25-hydroxy-13(24),15,17-cheilanthatrien-19,25-olide::CHEMBL478798	MAP kinase-activated protein kinase 2	Homo sapiens		 90000							ChEMBL	10.1021/np0004597	10.7270/Q2HT2P3X	11277743			Buchanan, MS; Edser, A; King, G; Whitmore, J; Quinn, RJ	AstraZeneca R&D Griffith University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269815&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11632412	104115281		CHEMBL478798				ZINC35967637	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50176061	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)[C@H](CC(O)C3=CC(=O)OC3O)C(=C)CC[C@H]21	InChI=1S/C25H38O4/c1-15-7-8-20-24(4,12-9-19-23(2,3)10-6-11-25(19,20)5)17(15)14-18(26)16-13-21(27)29-22(16)28/h13,17-20,22,26,28H,1,6-12,14H2,2-5H3/t17-,18?,19+,20+,22?,24+,25+/m1/s1	LWTIZOHDKCIZPP-XHEWZUHNSA-N	50269822	16,25-dihydroxy-13(24),17-cheilanthadien-19,25-olide::CHEMBL476479	MAP kinase-activated protein kinase 2	Homo sapiens		 90000							ChEMBL	10.1021/np0004597	10.7270/Q2HT2P3X	11277743			Buchanan, MS; Edser, A; King, G; Whitmore, J; Quinn, RJ	AstraZeneca R&D Griffith University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269822&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			21590534	104115284		CHEMBL476479				ZINC40405881	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50176062	CC1(C)CCC[C@@]2(C)[C@H]1CC[C@@]1(C)[C@H](CC3OC(=O)C=C3CO)C(=C)CC[C@H]21	InChI=1S/C25H38O3/c1-16-7-8-21-24(4,18(16)14-19-17(15-26)13-22(27)28-19)12-9-20-23(2,3)10-6-11-25(20,21)5/h13,18-21,26H,1,6-12,14-15H2,2-5H3/t18-,19?,20+,21+,24+,25+/m1/s1	IDZSBARYKPRHAX-TWTOBAAQSA-N	50269821	25-hydroxy-13(24),17-cheilanthadien-16,19-olide::CHEMBL515940	MAP kinase-activated protein kinase 2	Homo sapiens		 90000							ChEMBL	10.1021/np0004597	10.7270/Q2HT2P3X	11277743			Buchanan, MS; Edser, A; King, G; Whitmore, J; Quinn, RJ	AstraZeneca R&D Griffith University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269821&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			21590533	104115283		CHEMBL515940				ZINC40918608	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50176063	C[C@]12CC[C@H]3[C@@](C)(CC[C@H]4C(C)(C)CCC[C@]34C)[C@@H]1C[C@@H](O2)C1=CC(=O)OC1O	InChI=1S/C25H38O4/c1-22(2)9-6-10-23(3)17(22)7-11-24(4)18(23)8-12-25(5)19(24)14-16(29-25)15-13-20(26)28-21(15)27/h13,16-19,21,27H,6-12,14H2,1-5H3/t16-,17+,18-,19+,21?,23+,24-,25+/m1/s1	NSNPNVMHENRPQH-BPXGIISOSA-N	50269820	13,16-epoxy-25-hydroxy-17-cheilanthen-19,25-olide::CHEMBL476478	MAP kinase-activated protein kinase 2	Homo sapiens		 90000							ChEMBL	10.1021/np0004597	10.7270/Q2HT2P3X	11277743			Buchanan, MS; Edser, A; King, G; Whitmore, J; Quinn, RJ	AstraZeneca R&D Griffith University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50269820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50269820&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10621161	104115282		CHEMBL476478				ZINC38838149	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50197570	[O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1ccc(F)cc1Cl	InChI=1S/C20H10Cl3FN2O/c21-15-2-1-3-16(22)18(15)20-19-14(7-9-26(20)27)12(6-8-25-19)13-5-4-11(24)10-17(13)23/h1-10H	AUZOBOALIFKXNA-UHFFFAOYSA-N	50357884	CHEMBL1916359	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm200975u	10.7270/Q2MW2HKR	21999461			Lumeras, W; Vidal, L; Vidal, B; Balague, C; Orellana, A; Maldonado, M; Dominguez, M; Segarra, V; Caturla, F	Rh&#244;ne-Poulenc Rorer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357884&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24896769	136961908		CHEMBL1916359				ZINC73162320	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50212049	C[C@@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N	InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1	UJLAWZDWDVHWOW-YPMHNXCESA-N	50193995	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile::CHEMBL221959::CP-690550::TOFACITINIB CITRATE::Tofacitinib::Tofacitinib citrate (1)::US10112907, Example 00035::US10399979, Compound Tofacitinib::US10766894, Compound TABLE 1.20::US10875847, Compound Tofacitinib::US11078206, Example Tofacitinib::US11203595, TABLE 1.20::US11339167, Example Tofacitinib	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1126/science.1087061	10.7270/Q22Z16FK	14593182			Changelian, PS; Flanagan, ME; Ball, DJ; Kent, CR; Magnuson, KS; Martin, WH; Rizzuti, BJ; Sawyer, PS; Perry, BD; Brissette, WH; McCurdy, SP; Kudlacz, EM; Conklyn, MJ; Elliott, EA; Koslov, ER; Fisher, MB; Strelevitz, TJ; Yoon, K; Whipple, DA; Sun, J; Munchhof, MJ; Doty, JL; Casavant, JM; Blumenkopf, TA; Hines, M; Brown, MF; Lillie, BM; Subramanyam, C; Shang-Poa, C; Milici, AJ; Beckius, GE; Moyer, JD; Su, C; Woodworth, TG; Gaweco, AS; Beals, CR; Littman, BH; Fisher, DA; Smith, JF; Zagouras, P; Magna, HA; Saltarelli, MJ; Johnson, KS; Nelms, LF; Des Etages, SG; Hayes, LS; Kawabata, TT; Finco-Kent, D; Baker, DL; Larson, M; Si, MS; Paniagua, R; Higgins, J; Holm, B; Reitz, B; Zhou, YJ; Morris, RE; O'Shea, JJ; Borie, DC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193995&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MI1	3LXK,3LXN,4OTI,3EYG,3FUP	9926791	104076339	71200	CHEMBL221959	DB08183	5677		ZINC03818808	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216061	COc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H23N3O3/c1-27-19-8-2-16(3-9-19)20-10-11-21(28-20)22(26)24-17-4-6-18(7-5-17)25-14-12-23-13-15-25/h2-11,23H,12-15H2,1H3,(H,24,26)	DYJGGYMCCGHJMT-UHFFFAOYSA-N	50380293	CHEMBL2017447	MAP kinase-activated protein kinase 2	Homo sapiens		 22000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380293&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689580	160859376		CHEMBL2017447				ZINC84617209	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216062	FC(F)(F)c1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H20F3N3O2/c23-22(24,25)16-3-1-15(2-4-16)19-9-10-20(30-19)21(29)27-17-5-7-18(8-6-17)28-13-11-26-12-14-28/h1-10,26H,11-14H2,(H,27,29)	FRYRKVNSTORMGJ-UHFFFAOYSA-N	50380292	CHEMBL2017446	MAP kinase-activated protein kinase 2	Homo sapiens		 20000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380292&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691710	160859375		CHEMBL2017446				ZINC84617207	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216063	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	CAIGVNVLJGDZSF-UHFFFAOYSA-N	50362169	CHEMBL1938680	MAP kinase-activated protein kinase 2	Homo sapiens		 5500							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362169&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401151	136966231		CHEMBL1938680				ZINC73224553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216064	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216065	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	CAIGVNVLJGDZSF-UHFFFAOYSA-N	50362169	CHEMBL1938680	MAP kinase-activated protein kinase 2	Homo sapiens				 2000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362169&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401151	136966231		CHEMBL1938680				ZINC73224553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216066	FC(F)(F)c1cc(ccc1NC(=O)c1ccc(o1)-c1ccc(Cl)cc1)N1CCNCC1	InChI=1S/C22H19ClF3N3O2/c23-15-3-1-14(2-4-15)19-7-8-20(31-19)21(30)28-18-6-5-16(13-17(18)22(24,25)26)29-11-9-27-10-12-29/h1-8,13,27H,9-12H2,(H,28,30)	XMDGCSWRCZWUON-UHFFFAOYSA-N	50380296	CHEMBL2017450	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380296&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70687521	160859379		CHEMBL2017450				ZINC84617210	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216067	Fc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)ccc1N1CCNCC1	InChI=1S/C21H19ClFN3O2/c22-15-3-1-14(2-4-15)19-7-8-20(28-19)21(27)25-16-5-6-18(17(23)13-16)26-11-9-24-10-12-26/h1-8,13,24H,9-12H2,(H,25,27)	IMZWHTLABIYNHC-UHFFFAOYSA-N	50380295	CHEMBL2017449	MAP kinase-activated protein kinase 2	Homo sapiens		 6700							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380295&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685386	160859378		CHEMBL2017449				ZINC84636070	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216068	Clc1ccc(s1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C19H18ClN3O2S/c20-18-8-7-17(26-18)15-5-6-16(25-15)19(24)22-13-1-3-14(4-2-13)23-11-9-21-10-12-23/h1-8,21H,9-12H2,(H,22,24)	RMSJFISUQPTNAQ-UHFFFAOYSA-N	50380294	CHEMBL2017448	MAP kinase-activated protein kinase 2	Homo sapiens		 6900							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380294&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689581	160859377		CHEMBL2017448				ZINC84619457	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216070	Clc1ccc(cc1)-c1nc(cs1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C20H19ClN4OS/c21-15-3-1-14(2-4-15)20-24-18(13-27-20)19(26)23-16-5-7-17(8-6-16)25-11-9-22-10-12-25/h1-8,13,22H,9-12H2,(H,23,26)	QGNVFBKITUGHJH-UHFFFAOYSA-N	50380301	CHEMBL2017455	MAP kinase-activated protein kinase 2	Homo sapiens		 9500							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380301&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685387	160859384		CHEMBL2017455				ZINC84596668	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216071	Clc1ccc(cc1)-c1ccc(s1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3OS/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	FEMAFCHAYMYMMA-UHFFFAOYSA-N	50380300	CHEMBL2017454	MAP kinase-activated protein kinase 2	Homo sapiens		 9000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380300&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70681191	160859383		CHEMBL2017454				ZINC84586647	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216072	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)C1=CCNCC1	InChI=1S/C22H19ClN2O2/c23-18-5-1-17(2-6-18)20-9-10-21(27-20)22(26)25-19-7-3-15(4-8-19)16-11-13-24-14-12-16/h1-11,24H,12-14H2,(H,25,26)	CKDXGBVERZNORW-UHFFFAOYSA-N	50380298	CHEMBL2017452	MAP kinase-activated protein kinase 2	Homo sapiens		 2100							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380298&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691711	160859381		CHEMBL2017452				ZINC84635037	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216073	Clc1ccc(cc1)-c1cccc(n1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H21ClN4O/c23-17-6-4-16(5-7-17)20-2-1-3-21(26-20)22(28)25-18-8-10-19(11-9-18)27-14-12-24-13-15-27/h1-11,24H,12-15H2,(H,25,28)	PDVROLFZQHGTNZ-UHFFFAOYSA-N	50380303	CHEMBL2017457	MAP kinase-activated protein kinase 2	Homo sapiens				 3900					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380303&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70695897	160859386		CHEMBL2017457				ZINC84635929	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216074	CN1CCN(CC1)c1ccc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1	InChI=1S/C22H22ClN3O2/c1-25-12-14-26(15-13-25)19-8-6-18(7-9-19)24-22(27)21-11-10-20(28-21)16-2-4-17(23)5-3-16/h2-11H,12-15H2,1H3,(H,24,27)	QONRQALSXOAURD-UHFFFAOYSA-N	51932	5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide::5-(4-chlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide::5-(4-chlorophenyl)-N-[4-(4-methylpiperazino)phenyl]-2-furamide::CHEMBL1392696::MLS001125449::SMR000665983::cid_1494312	MAP kinase-activated protein kinase 2	Homo sapiens				 20000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51932&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			1494312	252632089		CHEMBL1392696				ZINC13124188	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216075	Clc1ccc(cc1)-c1cc(no1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C20H19ClN4O2/c21-15-3-1-14(2-4-15)19-13-18(24-27-19)20(26)23-16-5-7-17(8-6-16)25-11-9-22-10-12-25/h1-8,13,22H,9-12H2,(H,23,26)	NQRMAIQQUZVZOY-UHFFFAOYSA-N	50380302	CHEMBL2017456	MAP kinase-activated protein kinase 2	Homo sapiens				 1900					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380302&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689582	160859385		CHEMBL2017456				ZINC84616903	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216079	Cc1cc(Cl)ccc1-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H22ClN3O2/c1-15-14-16(23)2-7-19(15)20-8-9-21(28-20)22(27)25-17-3-5-18(6-4-17)26-12-10-24-11-13-26/h2-9,14,24H,10-13H2,1H3,(H,25,27)	JBPZEDJNSIAVPF-UHFFFAOYSA-N	50380291	CHEMBL2017445	MAP kinase-activated protein kinase 2	Homo sapiens		 5900							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380291&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691709	160859374		CHEMBL2017445				ZINC84587309	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216080	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccncc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-22-3-1-21(2-4-22)25-9-10-26(34-25)27(33)32(19-20-11-13-29-14-12-20)24-7-5-23(6-8-24)31-17-15-30-16-18-31/h1-14,30H,15-19H2	MTGHRYOPMOQODT-UHFFFAOYSA-N	50380310	CHEMBL2017619	MAP kinase-activated protein kinase 2	Homo sapiens				 530					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380310&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689597	160859393		CHEMBL2017619				ZINC84596044	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216081	Cn1ccnc1CN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C26H26ClN5O2/c1-30-15-14-29-25(30)18-32(22-8-6-21(7-9-22)31-16-12-28-13-17-31)26(33)24-11-10-23(34-24)19-2-4-20(27)5-3-19/h2-11,14-15,28H,12-13,16-18H2,1H3	XBEPLNIHFRVFRL-UHFFFAOYSA-N	50380309	CHEMBL2017463	MAP kinase-activated protein kinase 2	Homo sapiens				 4000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380309&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70687522	160859392		CHEMBL2017463				ZINC84634034	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216082	CCCCN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C25H28ClN3O2/c1-2-3-16-29(22-10-8-21(9-11-22)28-17-14-27-15-18-28)25(30)24-13-12-23(31-24)19-4-6-20(26)7-5-19/h4-13,27H,2-3,14-18H2,1H3	RWGDJQOBAYWTBP-UHFFFAOYSA-N	50380308	CHEMBL2017462	MAP kinase-activated protein kinase 2	Homo sapiens				 1800					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380308&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691713	160859391		CHEMBL2017462				ZINC84633523	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216083	Clc1ccc(-c2ccc(o2)C(=O)Nc2ccc(cc2)N2CCNCC2)c(Cl)c1	InChI=1S/C21H19Cl2N3O2/c22-14-1-6-17(18(23)13-14)19-7-8-20(28-19)21(27)25-15-2-4-16(5-3-15)26-11-9-24-10-12-26/h1-8,13,24H,9-12H2,(H,25,27)	GJQZQVRIRSQPIP-UHFFFAOYSA-N	50380290	CHEMBL2017444	MAP kinase-activated protein kinase 2	Homo sapiens		 7600							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380290&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70687520	160859373		CHEMBL2017444				ZINC84617753	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216084	CC(C)N(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C24H26ClN3O2/c1-17(2)28(21-9-7-20(8-10-21)27-15-13-26-14-16-27)24(29)23-12-11-22(30-23)18-3-5-19(25)6-4-18/h3-12,17,26H,13-16H2,1-2H3	YFRABOFOMDNCOG-UHFFFAOYSA-N	50380307	CHEMBL2017461	MAP kinase-activated protein kinase 2	Homo sapiens				 2700					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380307&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685388	160859390		CHEMBL2017461				ZINC84633522	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216085	Clc1cccc(c1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-2-15(14-16)19-8-9-20(27-19)21(26)24-17-4-6-18(7-5-17)25-12-10-23-11-13-25/h1-9,14,23H,10-13H2,(H,24,26)	PPDZWHVZYSPBOB-UHFFFAOYSA-N	50380289	CHEMBL2017443	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380289&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691708	160859372		CHEMBL2017443				ZINC84619537	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216086	CCCN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C24H26ClN3O2/c1-2-15-28(21-9-7-20(8-10-21)27-16-13-26-14-17-27)24(29)23-12-11-22(30-23)18-3-5-19(25)6-4-18/h3-12,26H,2,13-17H2,1H3	KASPOQKBLGLGBP-UHFFFAOYSA-N	50380306	CHEMBL2017460	MAP kinase-activated protein kinase 2	Homo sapiens				 3000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380306&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691712	160859389		CHEMBL2017460				ZINC84596801	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216087	Clc1ccccc1-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-18-4-2-1-3-17(18)19-9-10-20(27-19)21(26)24-15-5-7-16(8-6-15)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	OAWGNEGVOIDOJR-UHFFFAOYSA-N	50380288	CHEMBL2017442	MAP kinase-activated protein kinase 2	Homo sapiens		 8000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380288&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685385	160859371		CHEMBL2017442				ZINC84587306	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216088	CCN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C23H24ClN3O2/c1-2-27(20-9-7-19(8-10-20)26-15-13-25-14-16-26)23(28)22-12-11-21(29-22)17-3-5-18(24)6-4-17/h3-12,25H,2,13-16H2,1H3	ZQXYAXCRCBTDIH-UHFFFAOYSA-N	50380305	CHEMBL2017459	MAP kinase-activated protein kinase 2	Homo sapiens				 800					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380305&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70695898	160859388		CHEMBL2017459				ZINC84596616	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50216089	CN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C22H22ClN3O2/c1-25(18-6-8-19(9-7-18)26-14-12-24-13-15-26)22(27)21-11-10-20(28-21)16-2-4-17(23)5-3-16/h2-11,24H,12-15H2,1H3	VVLMVMQNQKVXTF-UHFFFAOYSA-N	50380304	CHEMBL2017458	MAP kinase-activated protein kinase 2	Homo sapiens				 9000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380304&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689583	160859387		CHEMBL2017458				ZINC84635931	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50229758	CCN(CC)CC=Cc1[nH]c(=O)c2c3n(C)c(Nc4c(Cl)cccc4Cl)nc3ccc2c1C	InChI=1S/C25H27Cl2N5O/c1-5-32(6-2)14-8-11-19-15(3)16-12-13-20-23(21(16)24(33)28-19)31(4)25(29-20)30-22-17(26)9-7-10-18(22)27/h7-13H,5-6,14H2,1-4H3,(H,28,33)(H,29,30)	BPLTVYXMXOYIBK-UHFFFAOYSA-N	50126732	2-(2,6-Dichloro-phenylamino)-7-(3-diethylamino-propenyl)-1,6-dimethyl-1,8-dihydro-imidazo[4,5-h]isoquinolin-9-one::CHEMBL281957	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL	10.1021/jm020446l	10.7270/Q2DN44FW	12672234			Goldberg, DR; Butz, T; Cardozo, MG; Eckner, RJ; Hammach, A; Huang, J; Jakes, S; Kapadia, S; Kashem, M; Lukas, S; Morwick, TM; Panzenbeck, M; Patel, U; Pav, S; Peet, GW; Peterson, JD; Prokopowicz, AS; Snow, RJ; Sellati, R; Takahashi, H; Tan, J; Tschantz, MA; Wang, XJ; Wang, Y; Wolak, J; Xiong, P; Moss, N	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126732	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126732&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9869943	104018806		CHEMBL281957				ZINC01494202	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50230907	NC(=O)c1cc([nH]c1-c1ccccc1)-c1ccnc(N)n1	InChI=1S/C15H13N5O/c16-14(21)10-8-12(11-6-7-18-15(17)20-11)19-13(10)9-4-2-1-3-5-9/h1-8,19H,(H2,16,21)(H2,17,18,20)	VOQXQYXTZZHYBF-UHFFFAOYSA-N	50329427	5-(2-Amino-pyrimidin-4-yl)-2-phenyl-1H-pyrrole-3-carboxamide::CHEMBL1270230::US9670191, U1	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm100504d	10.7270/Q24T6JM3	20873740			Menichincheri, M; Albanese, C; Alli, C; Ballinari, D; Bargiotti, A; Caldarelli, M; Ciavolella, A; Cirla, A; Colombo, M; Colotta, F; Croci, V; D'Alessio, R; D'Anello, M; Ermoli, A; Fiorentini, F; Forte, B; Galvani, A; Giordano, P; Isacchi, A; Martina, K; Molinari, A; Moll, JK; Montagnoli, A; Orsini, P; Orzi, F; Pesenti, E; Pillan, A; Roletto, F; Scolaro, A; Tato, M; Tibolla, M; Valsasina, B; Varasi, M; Vianello, P; Volpi, D; Santocanale, C; Vanotti, E	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50329427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50329427&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24809764	123108542		CHEMBL1270230				ZINC64528488	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50227882	CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1	BMGQWWVMWDBQGC-IIFHNQTCSA-N	50326053	CHEMBL608533::PKC-412	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326053	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326053&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	2K2	4NCT	9829523	123105168	63452	CHEMBL608533					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50230337	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	MAP kinase-activated protein kinase 2	Homo sapiens			 880						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50274751	Nc1nc2c3c(F)cccc3nc(Cc3ccc4OCOc4c3)n2n1	InChI=1S/C17H12FN5O2/c18-10-2-1-3-11-15(10)16-21-17(19)22-23(16)14(20-11)7-9-4-5-12-13(6-9)25-8-24-12/h1-6H,7-8H2,(H2,19,22)	OWLAKERMHYDWTB-UHFFFAOYSA-N	50048357	CHEMBL3309990	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2014.05.056	10.7270/Q2S46TMD	24980703			Casale, E; Amboldi, N; Brasca, MG; Caronni, D; Colombo, N; Dalvit, C; Felder, ER; Fogliatto, G; Galvani, A; Isacchi, A; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Casuscelli, F	Nerviano Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048357	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048357&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	HAJ	4CWR	51037112	313068942		CHEMBL3309990					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50274752	Nc1nc2c3ccc(N)cc3nc(Cc3ccc4OCOc4c3)n2n1	InChI=1S/C17H14N6O2/c18-10-2-3-11-12(7-10)20-15(23-16(11)21-17(19)22-23)6-9-1-4-13-14(5-9)25-8-24-13/h1-5,7H,6,8,18H2,(H2,19,22)	FGNQVZZMORDWIZ-UHFFFAOYSA-N	50048362	CHEMBL3309995	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2014.05.056	10.7270/Q2S46TMD	24980703			Casale, E; Amboldi, N; Brasca, MG; Caronni, D; Colombo, N; Dalvit, C; Felder, ER; Fogliatto, G; Galvani, A; Isacchi, A; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Casuscelli, F	Nerviano Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048362&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			51036677	313068947		CHEMBL3309995					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50274753	OCCCNc1ccc2c3ncnn3c(nc2c1)-c1ccc2OCOc2c1	InChI=1S/C19H17N5O3/c25-7-1-6-20-13-3-4-14-15(9-13)23-18(24-19(14)21-10-22-24)12-2-5-16-17(8-12)27-11-26-16/h2-5,8-10,20,25H,1,6-7,11H2	GIAVVFIPFBOBRR-UHFFFAOYSA-N	50048364	CHEMBL3309997	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2014.05.056	10.7270/Q2S46TMD	24980703			Casale, E; Amboldi, N; Brasca, MG; Caronni, D; Colombo, N; Dalvit, C; Felder, ER; Fogliatto, G; Galvani, A; Isacchi, A; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Casuscelli, F	Nerviano Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048364	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048364&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118706214	313068949		CHEMBL3309997					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50274754	Nc1nc2c3ccc(NCCO)cc3nc(Cc3ccc4OCOc4c3)n2n1	InChI=1S/C19H18N6O3/c20-19-23-18-13-3-2-12(21-5-6-26)9-14(13)22-17(25(18)24-19)8-11-1-4-15-16(7-11)28-10-27-15/h1-4,7,9,21,26H,5-6,8,10H2,(H2,20,24)	QPVNTDBWWRFMIC-UHFFFAOYSA-N	50048365	CHEMBL3309998	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2014.05.056	10.7270/Q2S46TMD	24980703			Casale, E; Amboldi, N; Brasca, MG; Caronni, D; Colombo, N; Dalvit, C; Felder, ER; Fogliatto, G; Galvani, A; Isacchi, A; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Casuscelli, F	Nerviano Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048365	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048365&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	G3R	4CWS	50938552	313068950		CHEMBL3309998					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50274755	CN1CCN(CC1)c1cc(F)c2c3nc(N)nn3c(Cc3ccc4OCOc4c3)nc2c1	InChI=1S/C22H22FN7O2/c1-28-4-6-29(7-5-28)14-10-15(23)20-16(11-14)25-19(30-21(20)26-22(24)27-30)9-13-2-3-17-18(8-13)32-12-31-17/h2-3,8,10-11H,4-7,9,12H2,1H3,(H2,24,27)	QUYGYUVUHYMMRW-UHFFFAOYSA-N	50048374	CHEMBL3310151	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2014.05.056	10.7270/Q2S46TMD	24980703			Casale, E; Amboldi, N; Brasca, MG; Caronni, D; Colombo, N; Dalvit, C; Felder, ER; Fogliatto, G; Galvani, A; Isacchi, A; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Casuscelli, F	Nerviano Medical Sciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50048374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50048374&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			51037948	313068959		CHEMBL3310151					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268468	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)N1CCNCC1	InChI=1S/C23H21ClN4O/c24-18-3-1-17(2-4-18)21-9-10-22(29-21)23-26-13-16-28(23)20-7-5-19(6-8-20)27-14-11-25-12-15-27/h1-10,13,16,25H,11-12,14-15H2	SLLRTLCGZRODTB-UHFFFAOYSA-N	50045370	CHEMBL3314140	MAP kinase-activated protein kinase 2	Homo sapiens		 2139							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045370&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91971978	103976419		CHEMBL3314140				ZINC13282471	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268505	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3cncnc3)C(=O)c2o1)N1CCNCC1	InChI=1S/C33H28ClN5O2/c34-27-7-5-22(6-8-27)31-17-25-15-24-16-28(38-13-11-35-12-14-38)9-10-30(24)39(33(40)32(25)41-31)20-23-3-1-2-4-29(23)26-18-36-21-37-19-26/h1-10,16-19,21,35H,11-15,20H2	DUPVSFMZABNMJA-UHFFFAOYSA-N	50434489	CHEMBL2385547	MAP kinase-activated protein kinase 2	Homo sapiens		 5.7							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434489&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251322	175446806		CHEMBL2385547				ZINC72314982	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268506	OC1(CCNCC1)c1ccc(cc1)-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C25H22N4O2/c26-17-18-1-3-19(4-2-18)22-9-10-23(31-22)24-28-15-16-29(24)21-7-5-20(6-8-21)25(30)11-13-27-14-12-25/h1-10,15-16,27,30H,11-14H2	DJUWCEOXGPITNM-UHFFFAOYSA-N	50045371	CHEMBL3315292	MAP kinase-activated protein kinase 2	Homo sapiens		 26							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045371	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045371&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708087	103976420		CHEMBL3315292				ZINC26646047	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268507	FC1(CCNCC1)c1ccc(cc1)-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C25H21FN4O/c26-25(11-13-28-14-12-25)20-5-7-21(8-6-20)30-16-15-29-24(30)23-10-9-22(31-23)19-3-1-18(17-27)2-4-19/h1-10,15-16,28H,11-14H2	SLXIIOZKZIKSPV-UHFFFAOYSA-N	50045373	CHEMBL3315291	MAP kinase-activated protein kinase 2	Homo sapiens		 25							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045373	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045373&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708086	103976422		CHEMBL3315291					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268508	OC1(CCNCC1)c1ccc(cc1)-n1ccnc1-c1ccc(o1)-c1ccc(Cl)cc1	InChI=1S/C24H22ClN3O2/c25-19-5-1-17(2-6-19)21-9-10-22(30-21)23-27-15-16-28(23)20-7-3-18(4-8-20)24(29)11-13-26-14-12-24/h1-10,15-16,26,29H,11-14H2	VUGGMXYOWPIBND-UHFFFAOYSA-N	50045374	CHEMBL3315290	MAP kinase-activated protein kinase 2	Homo sapiens		 26							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045374	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045374&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708085	103976423		CHEMBL3315290				ZINC01587126	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268509	FC1(CCNCC1)c1ccc(cc1)-n1ccnc1-c1ccc(o1)-c1ccc(Cl)cc1	InChI=1S/C24H21ClFN3O/c25-19-5-1-17(2-6-19)21-9-10-22(30-21)23-28-15-16-29(23)20-7-3-18(4-8-20)24(26)11-13-27-14-12-24/h1-10,15-16,27H,11-14H2	BPDRSYOIAMRYHS-UHFFFAOYSA-N	50045385	CHEMBL3315289	MAP kinase-activated protein kinase 2	Homo sapiens		 67							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045385&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708084	103976434		CHEMBL3315289				ZINC05140055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268510	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)[C@@H]1CNCCO1	InChI=1S/C23H20ClN3O2/c24-18-5-1-16(2-6-18)20-9-10-21(29-20)23-26-11-13-27(23)19-7-3-17(4-8-19)22-15-25-12-14-28-22/h1-11,13,22,25H,12,14-15H2/t22-/m0/s1	VOXIZJRMQQYLLS-QFIPXVFZSA-N	50045394	CHEMBL3315288	MAP kinase-activated protein kinase 2	Homo sapiens		 75							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045394&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708083	103976443		CHEMBL3315288				ZINC35572125	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268511	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)[C@H]1CNCCO1	InChI=1S/C23H20ClN3O2/c24-18-5-1-16(2-6-18)20-9-10-21(29-20)23-26-11-13-27(23)19-7-3-17(4-8-19)22-15-25-12-14-28-22/h1-11,13,22,25H,12,14-15H2/t22-/m1/s1	VOXIZJRMQQYLLS-JOCHJYFZSA-N	50045399	CHEMBL3315287	MAP kinase-activated protein kinase 2	Homo sapiens		 55							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045399&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708082	103976448		CHEMBL3315287				ZINC03794510	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268512	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)C1CNCC=C1	InChI=1S/C24H20ClN3O/c25-20-7-3-18(4-8-20)22-11-12-23(29-22)24-27-14-15-28(24)21-9-5-17(6-10-21)19-2-1-13-26-16-19/h1-12,14-15,19,26H,13,16H2	GTLIFCLVWKLWKI-UHFFFAOYSA-N	50045404	CHEMBL3315286	MAP kinase-activated protein kinase 2	Homo sapiens		 65							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045404&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708081	313068403		CHEMBL3315286					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268513	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)-c1cccnc1	InChI=1S/C24H16ClN3O/c25-20-7-3-18(4-8-20)22-11-12-23(29-22)24-27-14-15-28(24)21-9-5-17(6-10-21)19-2-1-13-26-16-19/h1-16H	OSKPTBJTSBEKJH-UHFFFAOYSA-N	50045405	CHEMBL3315285	MAP kinase-activated protein kinase 2	Homo sapiens		 3390							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045405&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118708080	313068404		CHEMBL3315285					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268514	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)-c1ccncc1	InChI=1S/C24H16ClN3O/c25-20-5-1-19(2-6-20)22-9-10-23(29-22)24-27-15-16-28(24)21-7-3-17(4-8-21)18-11-13-26-14-12-18/h1-16H	AJMLIFIYLIPWOM-UHFFFAOYSA-N	50045406	CHEMBL3314158	MAP kinase-activated protein kinase 2	Homo sapiens		 3730							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045406&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707430	313068405		CHEMBL3314158					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268515	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)C1CCCCN1	InChI=1S/C24H22ClN3O/c25-19-8-4-18(5-9-19)22-12-13-23(29-22)24-27-15-16-28(24)20-10-6-17(7-11-20)21-3-1-2-14-26-21/h4-13,15-16,21,26H,1-3,14H2	AYOKKAGQVOATKD-UHFFFAOYSA-N	50045407	CHEMBL3314157	MAP kinase-activated protein kinase 2	Homo sapiens		 160							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045407	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045407&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707429	313068406		CHEMBL3314157					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268516	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)C1CCCNC1	InChI=1S/C24H22ClN3O/c25-20-7-3-18(4-8-20)22-11-12-23(29-22)24-27-14-15-28(24)21-9-5-17(6-10-21)19-2-1-13-26-16-19/h3-12,14-15,19,26H,1-2,13,16H2	UUIIAYHWTPAHPU-UHFFFAOYSA-N	50045409	CHEMBL3314156	MAP kinase-activated protein kinase 2	Homo sapiens		 26							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045409&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707428	313068407		CHEMBL3314156					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268517	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)C1CCNCC1	InChI=1S/C24H22ClN3O/c25-20-5-1-19(2-6-20)22-9-10-23(29-22)24-27-15-16-28(24)21-7-3-17(4-8-21)18-11-13-26-14-12-18/h1-10,15-16,18,26H,11-14H2	XFSLOTUELHMEQA-UHFFFAOYSA-N	50045410	CHEMBL3314155	MAP kinase-activated protein kinase 2	Homo sapiens		 37							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045410&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707427	313068408		CHEMBL3314155					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268518	Brc1cc(ccc1N1CCNCC1)-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C24H20BrN5O/c25-20-15-19(5-6-21(20)29-12-9-27-10-13-29)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	PMEWPGUEJBPVBO-UHFFFAOYSA-N	50045411	CHEMBL3314154	MAP kinase-activated protein kinase 2	Homo sapiens		 36							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045411&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707426	313068409		CHEMBL3314154					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268519	Clc1cc(ccc1N1CCNCC1)-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C24H20ClN5O/c25-20-15-19(5-6-21(20)29-12-9-27-10-13-29)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	NZOZJWYMJYUXGF-UHFFFAOYSA-N	50045412	CHEMBL3314153	MAP kinase-activated protein kinase 2	Homo sapiens		 7.7							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045412&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707425	313068410		CHEMBL3314153					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268520	N#Cc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1-c1cncnc1)N1CCNCC1	InChI=1S/C28H23N7O/c29-16-20-1-3-21(4-2-20)26-7-8-27(36-26)28-33-11-14-35(28)25-6-5-23(34-12-9-30-10-13-34)15-24(25)22-17-31-19-32-18-22/h1-8,11,14-15,17-19,30H,9-10,12-13H2	RBQJMWUFXRARTJ-UHFFFAOYSA-N	50045413	CHEMBL3314152	MAP kinase-activated protein kinase 2	Homo sapiens		 44							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045413&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707424	313068411		CHEMBL3314152					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268521	FC(F)(F)c1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C25H20F3N5O/c26-25(27,28)20-15-19(32-12-9-30-10-13-32)5-6-21(20)33-14-11-31-24(33)23-8-7-22(34-23)18-3-1-17(16-29)2-4-18/h1-8,11,14-15,30H,9-10,12-13H2	ZNCDIMHJRBNKSQ-UHFFFAOYSA-N	50045414	CHEMBL3314151	MAP kinase-activated protein kinase 2	Homo sapiens		 31							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045414&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707423	313068412		CHEMBL3314151					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268522	Brc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C24H20BrN5O/c25-20-15-19(29-12-9-27-10-13-29)5-6-21(20)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	ZNOLHBSIGVMJEF-UHFFFAOYSA-N	50045415	CHEMBL3314150	MAP kinase-activated protein kinase 2	Homo sapiens		 22							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045415&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707422	313068413		CHEMBL3314150					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268523	Cc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C25H23N5O/c1-18-16-21(29-13-10-27-11-14-29)6-7-22(18)30-15-12-28-25(30)24-9-8-23(31-24)20-4-2-19(17-26)3-5-20/h2-9,12,15-16,27H,10-11,13-14H2,1H3	DVSQGESVOWVAQI-UHFFFAOYSA-N	50045416	CHEMBL3314149	MAP kinase-activated protein kinase 2	Homo sapiens		 17							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045416&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707421	313068414		CHEMBL3314149					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268524	Clc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C24H20ClN5O/c25-20-15-19(29-12-9-27-10-13-29)5-6-21(20)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	HUWBRFWESKZLQX-UHFFFAOYSA-N	50045417	CHEMBL3314148	MAP kinase-activated protein kinase 2	Homo sapiens		 13							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045417&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707420	313068415		CHEMBL3314148					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268525	Fc1cc(ccc1-n1ccnc1-c1ccc(o1)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C24H20FN5O/c25-20-15-19(29-12-9-27-10-13-29)5-6-21(20)30-14-11-28-24(30)23-8-7-22(31-23)18-3-1-17(16-26)2-4-18/h1-8,11,14-15,27H,9-10,12-13H2	BQPDWFAZEVCHPR-UHFFFAOYSA-N	50045418	CHEMBL3314147	MAP kinase-activated protein kinase 2	Homo sapiens		 16							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045418&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707419	313068416		CHEMBL3314147					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268526	Clc1ccc(cc1)-c1ccc(o1)-c1nc2ccccc2n1-c1ccc(cc1)N1CCNCC1	InChI=1S/C27H23ClN4O/c28-20-7-5-19(6-8-20)25-13-14-26(33-25)27-30-23-3-1-2-4-24(23)32(27)22-11-9-21(10-12-22)31-17-15-29-16-18-31/h1-14,29H,15-18H2	AAOLMRSBCMGWDX-UHFFFAOYSA-N	50045419	CHEMBL3314146	MAP kinase-activated protein kinase 2	Homo sapiens		 95							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045419&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707418	313068417		CHEMBL3314146					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268527	N#Cc1ccc(cc1)-c1ccc(o1)-c1nnnn1-c1ccc(cc1)N1CCNCC1	InChI=1S/C22H19N7O/c23-15-16-1-3-17(4-2-16)20-9-10-21(30-20)22-25-26-27-29(22)19-7-5-18(6-8-19)28-13-11-24-12-14-28/h1-10,24H,11-14H2	TZHVCEXCAKDTMC-UHFFFAOYSA-N	50045420	CHEMBL3314145	MAP kinase-activated protein kinase 2	Homo sapiens		 450							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045420&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707417	313068418		CHEMBL3314145					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268528	Clc1ccc(cc1)-c1ccc(o1)-c1ncnn1-c1ccc(cc1)N1CCNCC1	InChI=1S/C22H20ClN5O/c23-17-3-1-16(2-4-17)20-9-10-21(29-20)22-25-15-26-28(22)19-7-5-18(6-8-19)27-13-11-24-12-14-27/h1-10,15,24H,11-14H2	JFJJUGQSEOKEKC-UHFFFAOYSA-N	50045421	CHEMBL3314144	MAP kinase-activated protein kinase 2	Homo sapiens		 157							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045421&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707416	313068419		CHEMBL3314144					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268529	N#Cc1ccc(cc1)-c1ccc(o1)-c1nncn1-c1ccc(cc1)N1CCNCC1	InChI=1S/C23H20N6O/c24-15-17-1-3-18(4-2-17)21-9-10-22(30-21)23-27-26-16-29(23)20-7-5-19(6-8-20)28-13-11-25-12-14-28/h1-10,16,25H,11-14H2	SGQPFUFLNQMOHW-UHFFFAOYSA-N	50045422	CHEMBL3314143	MAP kinase-activated protein kinase 2	Homo sapiens		 23							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045422&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707415	313068420		CHEMBL3314143					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268530	Clc1ccc(cc1)-c1ccc(o1)-c1nncn1-c1ccc(cc1)N1CCNCC1	InChI=1S/C22H20ClN5O/c23-17-3-1-16(2-4-17)20-9-10-21(29-20)22-26-25-15-28(22)19-7-5-18(6-8-19)27-13-11-24-12-14-27/h1-10,15,24H,11-14H2	PHEIMVBULOHDAM-UHFFFAOYSA-N	50045423	CHEMBL3314142	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045423&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707414	313068421		CHEMBL3314142					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268531	N#Cc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)N1CCNCC1	InChI=1S/C24H21N5O/c25-17-18-1-3-19(4-2-18)22-9-10-23(30-22)24-27-13-16-29(24)21-7-5-20(6-8-21)28-14-11-26-12-15-28/h1-10,13,16,26H,11-12,14-15H2	GCFIVUQAQNZDRN-UHFFFAOYSA-N	50045425	CHEMBL3314141	MAP kinase-activated protein kinase 2	Homo sapiens		 85							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045425&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118707413	313068422		CHEMBL3314141					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50268532	Clc1ccc(cc1)-c1ccc(o1)-c1nccn1-c1ccc(cc1)N1CCNCC1	InChI=1S/C23H21ClN4O/c24-18-3-1-17(2-4-18)21-9-10-22(29-21)23-26-13-16-28(23)20-7-5-19(6-8-20)27-14-11-25-12-15-27/h1-10,13,16,25H,11-12,14-15H2	SLLRTLCGZRODTB-UHFFFAOYSA-N	50045370	CHEMBL3314140	MAP kinase-activated protein kinase 2	Homo sapiens		 26							ChEMBL	10.1016/j.bmcl.2014.05.024	10.7270/Q2F47QR7	24913714			Xiao, D; Zhu, X; Sofolarides, M; Degrado, S; Shao, N; Rao, A; Chen, X; Aslanian, R; Fossetta, J; Tian, F; Trivedi, P; Lundell, D; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50045370	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50045370&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91971978	103976419		CHEMBL3314140				ZINC13282471	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50291055	CC1=CC[C@H]2[C@@](C)(CC[C@H]3C(C)(C)CCC[C@]23C)[C@@H]1Cc1cc(ccc1O)C(O)=O	InChI=1S/C27H38O3/c1-17-7-10-23-26(4,14-11-22-25(2,3)12-6-13-27(22,23)5)20(17)16-19-15-18(24(29)30)8-9-21(19)28/h7-9,15,20,22-23,28H,6,10-14,16H2,1-5H3,(H,29,30)/t20-,22+,23+,26+,27+/m1/s1	VIOMEESUKISOEL-XDEZJFBHSA-N	50242186	(+)-Makassaric acid::CHEMBL454582	MAP kinase-activated protein kinase 2	Homo sapiens		 20000							ChEMBL	10.1021/np049808d	10.7270/Q2WQ03JB	15620270			Williams, DE; Telliez, JB; Liu, J; Tahir, A; van Soest, R; Andersen, RJ	University of British Columbia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242186	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242186&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11292790	104098977	66654	CHEMBL454582				ZINC34451458	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50291056	C\C(CCC1=C(C)CC[C@H]2C(C)(C)CCC[C@]12C)=C/Cc1cc(ccc1O)C(O)=O	InChI=1S/C27H38O3/c1-18(7-10-20-17-21(25(29)30)11-13-23(20)28)8-12-22-19(2)9-14-24-26(3,4)15-6-16-27(22,24)5/h7,11,13,17,24,28H,6,8-10,12,14-16H2,1-5H3,(H,29,30)/b18-7+/t24-,27+/m0/s1	RIYHRKNIDKXDII-UEKCLBEQSA-N	50242189	(+)-subersic acid::CHEMBL455101	MAP kinase-activated protein kinase 2	Homo sapiens		 9600							ChEMBL	10.1021/np049808d	10.7270/Q2WQ03JB	15620270			Williams, DE; Telliez, JB; Liu, J; Tahir, A; van Soest, R; Andersen, RJ	University of British Columbia	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242189	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242189&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11361892	104098980	66532	CHEMBL455101				ZINC14718345	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50288102	CONC(=O)c1ccc(C)c(Nc2nc(nc(n2)N2CCCN(C)CC2)N(C)CC(C)(C)C)c1	InChI=1S/C24H38N8O2/c1-17-9-10-18(20(33)29-34-7)15-19(17)25-21-26-22(31(6)16-24(2,3)4)28-23(27-21)32-12-8-11-30(5)13-14-32/h9-10,15H,8,11-14,16H2,1-7H3,(H,29,33)(H,25,26,27,28)	CFXVMISMBBBSCO-UHFFFAOYSA-N	16316	3-({4-[(2,2-dimethylpropyl)(methyl)amino]-6-(4-methyl-1,4-diazepan-1-yl)-1,3,5-triazin-2-yl}amino)-N-methoxy-4-methylbenzamide::CHEMBL225088::triaminotriazine aniline amide inhibitor, 1	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm049521d	10.7270/Q2WS8SR1	15566298			Leftheris, K; Ahmed, G; Chan, R; Dyckman, AJ; Hussain, Z; Ho, K; Hynes, J; Letourneau, J; Li, W; Lin, S; Metzger, A; Moriarty, KJ; Riviello, C; Shimshock, Y; Wen, J; Wityak, J; Wrobleski, ST; Wu, H; Wu, J; Desai, M; Gillooly, KM; Lin, TH; Loo, D; McIntyre, KW; Pitt, S; Shen, DR; Shuster, DJ; Zhang, R; Diller, D; Doweyko, A; Sack, J; Baldwin, J; Barrish, J; Dodd, J; Henderson, I; Kanner, S; Schieven, GL; Webb, M	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16316&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11454205	46516557		CHEMBL225088				ZINC13586099	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50290565	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1021/jm049486a	10.7270/Q2ZG6RRC	15615512			Lombardo, LJ; Lee, FY; Chen, P; Norris, D; Barrish, JC; Behnia, K; Castaneda, S; Cornelius, LA; Das, J; Doweyko, AM; Fairchild, C; Hunt, JT; Inigo, I; Johnston, K; Kamath, A; Kan, D; Klei, H; Marathe, P; Pang, S; Peterson, R; Pitt, S; Schieven, GL; Schmidt, RJ; Tokarski, J; Wen, ML; Wityak, J; Borzilleri, RM	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299931	CCNC1=C(C#N)C(CC2Oc3cc(O)c(O)cc3CC12)=NCC	InChI=1S/C18H21N3O3/c1-3-20-13-7-17-11(18(21-4-2)12(13)9-19)5-10-6-14(22)15(23)8-16(10)24-17/h6,8,11,17,21-23H,3-5,7H2,1-2H3	HJAILSWFRFAYEF-UHFFFAOYSA-N	50162630	1,3-Bis-ethylamino-6,7-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL181870	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162630&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936685	104048788		CHEMBL181870				ZINC40533215	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299932	COc1ccc2C(C(C#N)C#N)C3C(CC(=N)C(C#N)=C3N)Oc2c1	InChI=1S/C18H15N5O2/c1-24-10-2-3-11-14(4-10)25-15-5-13(22)12(8-21)18(23)17(15)16(11)9(6-19)7-20/h2-4,9,15-17,22H,5,23H2,1H3	OIRIQBOXUOLTAA-UHFFFAOYSA-N	50162629	2-(1,3-Diamino-2-cyano-6-methoxy-9,9a-dihydro-4aH-xanthen-9-yl)-malononitrile::CHEMBL180505	MAP kinase-activated protein kinase 2	Homo sapiens		 1940							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162629&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936684	104048787		CHEMBL180505				ZINC34804481	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299933	NC1=C(C#N)C(=N)CC2Oc3ccc(Br)cc3C(C(C#N)C#N)C12	InChI=1S/C17H12BrN5O/c18-9-1-2-13-10(3-9)15(8(5-19)6-20)16-14(24-13)4-12(22)11(7-21)17(16)23/h1-3,8,14-16,22H,4,23H2	SZGOYXNOXDRKCQ-UHFFFAOYSA-N	50162628	2-(1,3-Diamino-7-bromo-2-cyano-9,9a-dihydro-4aH-xanthen-9-yl)-malononitrile::CHEMBL179784	MAP kinase-activated protein kinase 2	Homo sapiens		 4220							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162628&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936683	104048786		CHEMBL179784				ZINC34804362	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299934	CCNC1=C(C#N)C(=N)CC2Oc3cc(O)c(O)cc3CC12	InChI=1S/C16H17N3O3/c1-2-19-16-9-3-8-4-12(20)13(21)6-14(8)22-15(9)5-11(18)10(16)7-17/h4,6,9,15,18-21H,2-3,5H2,1H3	FWGQASWHWIZGQS-UHFFFAOYSA-N	50162631	3-Amino-1-ethylamino-6,7-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL182439	MAP kinase-activated protein kinase 2	Homo sapiens		 419.0							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162631&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936686	104048789		CHEMBL182439				ZINC34804516	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299935	CCOc1cc2OC3CC(=N)C(C#N)=C(N)C3Cc2cc1O	InChI=1S/C16H17N3O3/c1-2-21-15-6-13-8(4-12(15)20)3-9-14(22-13)5-11(18)10(7-17)16(9)19/h4,6,9,14,18,20H,2-3,5,19H2,1H3	JNUOMCNGLYMZLA-UHFFFAOYSA-N	50162633	1,3-Diamino-6-ethoxy-7-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL360764	MAP kinase-activated protein kinase 2	Homo sapiens		 770							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162633&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936688	104048791		CHEMBL360764				ZINC34804329	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299936	NC1=C(C#N)C(=N)CC2Oc3cc(O)c(O)cc3CC12	InChI=1S/C14H13N3O3/c15-5-8-9(16)3-13-7(14(8)17)1-6-2-10(18)11(19)4-12(6)20-13/h2,4,7,13,16,18-19H,1,3,17H2	PREPNWXJQOKJTB-UHFFFAOYSA-N	50162634	1,3-Diamino-6,7-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL181212	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162634&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936689	104048792		CHEMBL181212				ZINC34804430	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299937	NC1=C(C#N)C(=N)CC2Oc3cc(C4COCCO4)c(O)cc3CC12	InChI=1S/C18H19N3O4/c19-7-12-13(20)6-16-11(18(12)21)3-9-4-14(22)10(5-15(9)25-16)17-8-23-1-2-24-17/h4-5,11,16-17,20,22H,1-3,6,8,21H2	WGBIXNYWULDFON-UHFFFAOYSA-N	50162637	1,3-Diamino-6-[1,4]dioxan-2-yl-7-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL178413	MAP kinase-activated protein kinase 2	Homo sapiens		 620							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162637&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936692	104048795		CHEMBL178413				ZINC34804308	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299938	NC1=C(C#N)C(=N)CC2Oc3c(CC12)ccc(O)c3O	InChI=1S/C14H13N3O3/c15-5-8-9(16)4-11-7(12(8)17)3-6-1-2-10(18)13(19)14(6)20-11/h1-2,7,11,16,18-19H,3-4,17H2	NEMMVEATRRXURO-UHFFFAOYSA-N	50162638	1,3-Diamino-5,6-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180362	MAP kinase-activated protein kinase 2	Homo sapiens		 850.0							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162638&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936693	104048796		CHEMBL180362				ZINC34804417	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299939	COc1ccc2C(C3C(CC(=N)C(C#N)=C3N)Oc2c1)c1ccccc1	InChI=1S/C21H19N3O2/c1-25-13-7-8-14-17(9-13)26-18-10-16(23)15(11-22)21(24)20(18)19(14)12-5-3-2-4-6-12/h2-9,18-20,23H,10,24H2,1H3	IHGPFBSASYMLRH-UHFFFAOYSA-N	50162640	1,3-Diamino-6-methoxy-9-phenyl-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL446938	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162640&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936695	104048798		CHEMBL446938				ZINC40834488	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299940	NC1=C(C#N)C(=N)CC2Oc3ccccc3CC12	InChI=1S/C14H13N3O/c15-7-10-11(16)6-13-9(14(10)17)5-8-3-1-2-4-12(8)18-13/h1-4,9,13,16H,5-6,17H2	QFGYTMRQASRUDP-UHFFFAOYSA-N	50162639	1,3-Diamino-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180054	MAP kinase-activated protein kinase 2	Homo sapiens		 560.0							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162639&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936694	104048797		CHEMBL180054				ZINC34804339	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299941	NC1=C(C#N)C(=N)CC2Oc3c(O)cccc3CC12	InChI=1S/C14H13N3O2/c15-6-9-10(16)5-12-8(13(9)17)4-7-2-1-3-11(18)14(7)19-12/h1-3,8,12,16,18H,4-5,17H2	MXZDHJJEZKVATA-UHFFFAOYSA-N	50162641	1,3-Diamino-5-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL182091	MAP kinase-activated protein kinase 2	Homo sapiens		 460							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162641&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936696	104048799		CHEMBL182091				ZINC34804387	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299942	Nc1nc2c(Cc3ccccc3S2(=O)=O)c(N)c1C#N	InChI=1S/C13H10N4O2S/c14-6-9-11(15)8-5-7-3-1-2-4-10(7)20(18,19)13(8)17-12(9)16/h1-4H,5H2,(H4,15,16,17)	WBZHPHDVFVKTCK-UHFFFAOYSA-N	50162642	2,4-Diamino-10,10-dioxo-5,10-dihydro-10lambda*6*-thiochromeno[2,3-b]pyridine-3-carbonitrile::CHEMBL180574	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162642&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9971229	104048800		CHEMBL180574				ZINC28124611	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299943	NC1=C(C#N)C(=N)CC2Oc3cc(O)ccc3C(C(C#N)C#N)C12	InChI=1S/C17H13N5O2/c18-5-8(6-19)15-10-2-1-9(23)3-13(10)24-14-4-12(21)11(7-20)17(22)16(14)15/h1-3,8,14-16,21,23H,4,22H2	FXTLPHXEAUTXLU-UHFFFAOYSA-N	50162643	2-(1,3-Diamino-2-cyano-6-hydroxy-9,9a-dihydro-4aH-xanthen-9-yl)-malononitrile::CHEMBL369332	MAP kinase-activated protein kinase 2	Homo sapiens		 12800							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162643&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936697	104048801		CHEMBL369332				ZINC40752667	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299944	Nc1nc2Sc3ccccc3Cc2c(N)c1C#N	InChI=1S/C13H10N4S/c14-6-9-11(15)8-5-7-3-1-2-4-10(7)18-13(8)17-12(9)16/h1-4H,5H2,(H4,15,16,17)	OVYQRAGJYYWTCW-UHFFFAOYSA-N	50162644	2,4-Diamino-5H-thiochromeno[2,3-b]pyridine-3-carbonitrile::CHEMBL178952	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162644&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10467496	104048802		CHEMBL178952				ZINC28124606	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299945	NC1=C(C#N)C(=N)CC2Oc3ccc(O)cc3CC12	InChI=1S/C14H13N3O2/c15-6-10-11(16)5-13-9(14(10)17)4-7-3-8(18)1-2-12(7)19-13/h1-3,9,13,16,18H,4-5,17H2	PJOMLFPVVDPQMV-UHFFFAOYSA-N	50162627	1,3-Diamino-7-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180959	MAP kinase-activated protein kinase 2	Homo sapiens		 470							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162627&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936682	104048785		CHEMBL180959				ZINC34804504	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299946	NC1=C(C#N)C(=N)CC2Oc3cc(OCN4CCCC4)ccc3CC12	InChI=1S/C19H22N4O2/c20-10-15-16(21)9-18-14(19(15)22)7-12-3-4-13(8-17(12)25-18)24-11-23-5-1-2-6-23/h3-4,8,14,18,21H,1-2,5-7,9,11,22H2	VYKFPPSJVIFFTC-UHFFFAOYSA-N	50162635	1,3-Diamino-6-(pyrrolidin-1-ylmethoxy)-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180510	MAP kinase-activated protein kinase 2	Homo sapiens		 1680							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936690	104048793		CHEMBL180510				ZINC34804528	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299947	OCCNC1=C(C#N)C(=N)CC2Oc3cc(O)c(O)cc3CC12	InChI=1S/C16H17N3O4/c17-7-10-11(18)5-15-9(16(10)19-1-2-20)3-8-4-12(21)13(22)6-14(8)23-15/h4,6,9,15,18-22H,1-3,5H2	WHKGFGSOXUPIAT-UHFFFAOYSA-N	50162647	3-Amino-6,7-dihydroxy-1-(2-hydroxy-ethylamino)-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180690	MAP kinase-activated protein kinase 2	Homo sapiens		 237							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162647&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936700	104048805		CHEMBL180690				ZINC34804457	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299948	CN1c2ccccc2Cc2c(N)c(C#N)c(N)nc12	InChI=1S/C14H13N5/c1-19-11-5-3-2-4-8(11)6-9-12(16)10(7-15)13(17)18-14(9)19/h2-5H,6H2,1H3,(H4,16,17,18)	HGOFWZOTBBXXJI-UHFFFAOYSA-N	50162650	2,4-Diamino-10-methyl-5,10-dihydro-benzo[b][1,8]naphthyridine-3-carbonitrile::CHEMBL360278	MAP kinase-activated protein kinase 2	Homo sapiens		 70000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162650	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162650&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10106198	104048808		CHEMBL360278				ZINC28121297	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299949	COc1cc2CC3C(CC(=N)C(C#N)=C3N)Oc2cc1OC	InChI=1S/C16H17N3O3/c1-20-14-4-8-3-9-13(22-12(8)6-15(14)21-2)5-11(18)10(7-17)16(9)19/h4,6,9,13,18H,3,5,19H2,1-2H3	VVVYJVDWAJHXEB-UHFFFAOYSA-N	50162632	1,3-Diamino-6,7-dimethoxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL182090	MAP kinase-activated protein kinase 2	Homo sapiens		 330							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162632&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936687	104048790		CHEMBL182090				ZINC34804376	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299950	NC1=C(C#N)C(=N)CC2Oc3ccc(O)cc3C(C(C#N)C#N)C12	InChI=1S/C17H13N5O2/c18-5-8(6-19)15-10-3-9(23)1-2-13(10)24-14-4-12(21)11(7-20)17(22)16(14)15/h1-3,8,14-16,21,23H,4,22H2	BNZGAHZHACLVEA-UHFFFAOYSA-N	50162645	2-(1,3-Diamino-2-cyano-7-hydroxy-9,9a-dihydro-4aH-xanthen-9-yl)-malononitrile::CHEMBL179336	MAP kinase-activated protein kinase 2	Homo sapiens		 3800							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162645&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936698	104048803		CHEMBL179336				ZINC34804296	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299951	CCCNC1=C(C#N)C(=N)CC2Oc3cc(O)c(O)cc3CC12	InChI=1S/C17H19N3O3/c1-2-3-20-17-10-4-9-5-13(21)14(22)7-15(9)23-16(10)6-12(19)11(17)8-18/h5,7,10,16,19-22H,2-4,6H2,1H3	JPXHHRHNZKNSRP-UHFFFAOYSA-N	50162649	3-Amino-6,7-dihydroxy-1-propylamino-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL183288	MAP kinase-activated protein kinase 2	Homo sapiens		 403							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162649	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162649&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936702	104048807		CHEMBL183288				ZINC34804443	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299952	NC1=C(C#N)C(=N)CC2Oc3cc(O)ccc3C(C12)c1ccccc1	InChI=1S/C20H17N3O2/c21-10-14-15(22)9-17-19(20(14)23)18(11-4-2-1-3-5-11)13-7-6-12(24)8-16(13)25-17/h1-8,17-19,22,24H,9,23H2	QCYGMIMYVDIWAD-UHFFFAOYSA-N	50162651	1,3-Diamino-6-hydroxy-9-phenyl-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL182088	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162651	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162651&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936703	104048809		CHEMBL182088				ZINC40533272	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299953	NC1=C(C#N)C(=N)CC2Oc3ccc(N)cc3CC12	InChI=1S/C14H14N4O/c15-6-10-11(17)5-13-9(14(10)18)4-7-3-8(16)1-2-12(7)19-13/h1-3,9,13,17H,4-5,16,18H2	SAAJAIYEZJEWQD-UHFFFAOYSA-N	50162648	1,3,7-Triamino-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180884	MAP kinase-activated protein kinase 2	Homo sapiens		 530							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162648&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936701	104048806		CHEMBL180884				ZINC34804403	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299954	COc1ccc2OC3CC(=N)C(C#N)=C(N)C3C(C(C#N)C#N)c2c1	InChI=1S/C18H15N5O2/c1-24-10-2-3-14-11(4-10)16(9(6-19)7-20)17-15(25-14)5-13(22)12(8-21)18(17)23/h2-4,9,15-17,22H,5,23H2,1H3	PJEOCYBRQUOHCH-UHFFFAOYSA-N	50162652	2-(1,3-Diamino-2-cyano-7-methoxy-9,9a-dihydro-4aH-xanthen-9-yl)-malononitrile::CHEMBL180490	MAP kinase-activated protein kinase 2	Homo sapiens		 6180							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162652	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162652&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936704	104048810		CHEMBL180490				ZINC34804469	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299955	NC1=C(C#N)C(=N)CC2Oc3cc(O)cc(O)c3CC12	InChI=1S/C14H13N3O3/c15-5-9-10(16)4-13-8(14(9)17)3-7-11(19)1-6(18)2-12(7)20-13/h1-2,8,13,16,18-19H,3-4,17H2	FZKBQQASNIQQIE-UHFFFAOYSA-N	50162636	1,3-Diamino-6,8-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL360551	MAP kinase-activated protein kinase 2	Homo sapiens		 690.0							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162636&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936691	104048794		CHEMBL360551				ZINC34804319	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299956	NC1=C(C#N)C(=N)CC2Oc3cc4OCCOc4cc3CC12	InChI=1S/C16H15N3O3/c17-7-10-11(18)5-13-9(16(10)19)3-8-4-14-15(6-12(8)22-13)21-2-1-20-14/h4,6,9,13,18H,1-3,5,19H2	RJQQQHQJELURRA-UHFFFAOYSA-N	50162646	8,10-Diamino-2,3,10a,11-tetrahydro-6aH-1,4,6-trioxa-naphthacene-9-carbonitrile::CHEMBL181069	MAP kinase-activated protein kinase 2	Homo sapiens		 490.0							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162646&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936699	104048804		CHEMBL181069				ZINC34804351	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50299957	NC1=C(C#N)C(=N)CC2Oc3cc(O)ccc3CC12	InChI=1S/C14H13N3O2/c15-6-10-11(16)5-13-9(14(10)17)3-7-1-2-8(18)4-12(7)19-13/h1-2,4,9,13,16,18H,3,5,17H2	DQVHGTZZFYOEQW-UHFFFAOYSA-N	50162653	1,3-Diamino-6-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL361425	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162653&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936705	104048811		CHEMBL361425				ZINC34804492	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50317600	CCc1c(NC(=O)OCCn2ccnc2)cn2ncnc(Nc3ccc4n(Cc5ccccc5)ncc4c3)c12	InChI=1S/C28H27N9O2/c1-2-23-24(34-28(38)39-13-12-35-11-10-29-19-35)17-37-26(23)27(30-18-32-37)33-22-8-9-25-21(14-22)15-31-36(25)16-20-6-4-3-5-7-20/h3-11,14-15,17-19H,2,12-13,16H2,1H3,(H,34,38)(H,30,32,33)	VTLGISZPEUFMGV-UHFFFAOYSA-N	13923	2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}carbamate::CHEMBL412367::pyrrolo[2,1-f][1,2,4]triazine analog 9b	MAP kinase-activated protein kinase 2	Homo sapiens		>25000							ChEMBL	10.1016/j.bmcl.2005.07.027	10.7270/Q2XD1172	16111887			Fink, BE; Vite, GD; Mastalerz, H; Kadow, JF; Kim, SH; Leavitt, KJ; Du, K; Crews, D; Mitt, T; Wong, TW; Hunt, JT; Vyas, DM; Tokarski, JS	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13923&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9871380	46514300		CHEMBL412367				ZINC03917624	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50321078	N#Cc1cnc2cnc(NCCN3CCOCC3)cc2c1Nc1ccc(Sc2ccccc2)cc1	InChI=1S/C27H26N6OS/c28-17-20-18-30-25-19-31-26(29-10-11-33-12-14-34-15-13-33)16-24(25)27(20)32-21-6-8-23(9-7-21)35-22-4-2-1-3-5-22/h1-9,16,18-19H,10-15H2,(H,29,31)(H,30,32)	HIASHEATKNRFJC-UHFFFAOYSA-N	50173833	6-(2-morpholinoethylamino)-4-(4-(phenylthio)phenylamino)-1,7-naphthyridine-3-carbonitrile::CHEMBL199210	MAP kinase-activated protein kinase 2	Homo sapiens		>400000							ChEMBL	10.1016/j.bmcl.2005.08.029	10.7270/Q2JS9Q0M	16165349			Gavrin, LK; Green, N; Hu, Y; Janz, K; Kaila, N; Li, HQ; Tam, SY; Thomason, JR; Gopalsamy, A; Ciszewski, G; Cuozzo, JW; Hall, JP; Hsu, S; Telliez, JB; Lin, LL	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173833&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16085320	104059696		CHEMBL199210				ZINC28529567	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50321099	N#Cc1cnc2cnc(NCCN3CCOCC3)cc2c1Nc1ccc(Oc2ccccc2)cc1	InChI=1S/C27H26N6O2/c28-17-20-18-30-25-19-31-26(29-10-11-33-12-14-34-15-13-33)16-24(25)27(20)32-21-6-8-23(9-7-21)35-22-4-2-1-3-5-22/h1-9,16,18-19H,10-15H2,(H,29,31)(H,30,32)	YUYWSKXPXLUJNA-UHFFFAOYSA-N	50173837	6-(2-morpholinoethylamino)-4-(4-phenoxyphenylamino)-1,7-naphthyridine-3-carbonitrile::6-[(2-morpholin-4-ylethyl)amino]-4-[(4-phenoxyphenyl)amino]-[1,7]naphthyridine-3-carbonitrile::CHEMBL371095	MAP kinase-activated protein kinase 2	Homo sapiens		>400000							ChEMBL	10.1016/j.bmcl.2005.08.029	10.7270/Q2JS9Q0M	16165349			Gavrin, LK; Green, N; Hu, Y; Janz, K; Kaila, N; Li, HQ; Tam, SY; Thomason, JR; Gopalsamy, A; Ciszewski, G; Cuozzo, JW; Hall, JP; Hsu, S; Telliez, JB; Lin, LL	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173837&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44405504	104059700		CHEMBL371095				ZINC28529954	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50321104	Fc1ccc(Nc2c(cnc3cnc(NCCN4CCOCC4)cc23)C#N)cc1Cl	InChI=1S/C21H20ClFN6O/c22-17-9-15(1-2-18(17)23)28-21-14(11-24)12-26-19-13-27-20(10-16(19)21)25-3-4-29-5-7-30-8-6-29/h1-2,9-10,12-13H,3-8H2,(H,25,27)(H,26,28)	IXQLEZDNYJWUTR-UHFFFAOYSA-N	29896	1,7-naphthyridine-3-carbonitrile, 1::CHEMBL197538	MAP kinase-activated protein kinase 2	Homo sapiens		>400000							ChEMBL	10.1016/j.bmcl.2005.08.029	10.7270/Q2JS9Q0M	16165349			Gavrin, LK; Green, N; Hu, Y; Janz, K; Kaila, N; Li, HQ; Tam, SY; Thomason, JR; Gopalsamy, A; Ciszewski, G; Cuozzo, JW; Hall, JP; Hsu, S; Telliez, JB; Lin, LL	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=29896	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=29896&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44143344	85147660		CHEMBL197538				ZINC28529863	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50321105	N#Cc1cnc2cnc(NCCN3CCOCC3)cc2c1Nc1ccc(Cc2ccccc2)cc1	InChI=1S/C28H28N6O/c29-18-23-19-31-26-20-32-27(30-10-11-34-12-14-35-15-13-34)17-25(26)28(23)33-24-8-6-22(7-9-24)16-21-4-2-1-3-5-21/h1-9,17,19-20H,10-16H2,(H,30,32)(H,31,33)	PXRDIWAVNLQFBI-UHFFFAOYSA-N	50173838	4-(4-benzylphenylamino)-6-(2-morpholinoethylamino)-1,7-naphthyridine-3-carbonitrile::CHEMBL371658	MAP kinase-activated protein kinase 2	Homo sapiens		>400000							ChEMBL	10.1016/j.bmcl.2005.08.029	10.7270/Q2JS9Q0M	16165349			Gavrin, LK; Green, N; Hu, Y; Janz, K; Kaila, N; Li, HQ; Tam, SY; Thomason, JR; Gopalsamy, A; Ciszewski, G; Cuozzo, JW; Hall, JP; Hsu, S; Telliez, JB; Lin, LL	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173838&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11496376	104059701		CHEMBL371658				ZINC28529865	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50321116	Fc1ccc(Nc2c(cnc3cnc(NCc4cccnc4)cc23)C#N)cc1Cl	InChI=1S/C21H14ClFN6/c22-17-6-15(3-4-18(17)23)29-21-14(8-24)11-26-19-12-28-20(7-16(19)21)27-10-13-2-1-5-25-9-13/h1-7,9,11-12H,10H2,(H,26,29)(H,27,28)	NMEUKWOOQOHUNA-UHFFFAOYSA-N	50173832	4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-1,7-naphthyridine-3-carbonitrile::4-(3-chloro-4-fluorophenylamino)-6-(pyridin-3-ylmethylamino)-[1,7]naphthyridine-3-carbonitrile::4-[(3-chloro-4-fluorophenyl)amino]-6-{[(1R)-1-phenylethyl]amino}-[1,7]naphthyridine-3-carbonitril::CHEMBL200381	MAP kinase-activated protein kinase 2	Homo sapiens		 110000							ChEMBL	10.1016/j.bmcl.2005.08.029	10.7270/Q2JS9Q0M	16165349			Gavrin, LK; Green, N; Hu, Y; Janz, K; Kaila, N; Li, HQ; Tam, SY; Thomason, JR; Gopalsamy, A; Ciszewski, G; Cuozzo, JW; Hall, JP; Hsu, S; Telliez, JB; Lin, LL	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50173832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50173832&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9549300	104059695		CHEMBL200381		6051		ZINC20148981	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50317954	CCCc1cc(O)c2c(O)cccc2c1-c1cc(O)cc(=O)o1	InChI=1S/C18H16O5/c1-2-4-10-7-14(21)18-12(5-3-6-13(18)20)17(10)15-8-11(19)9-16(22)23-15/h3,5-9,19-21H,2,4H2,1H3	XGGZRXUATHGLQU-UHFFFAOYSA-N	50241926	CHEMBL487190::Phaeochromycins A	MAP kinase-activated protein kinase 2	Homo sapiens		 39000							ChEMBL	10.1021/np0500629	10.7270/Q2BR8RXJ	16124774			Graziani, EI; Ritacco, FV; Bernan, VS; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241926&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54694607	104098905		CHEMBL487190				ZINC14650427	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50317955	CCCc1cc(=O)c2c(Cc3cc(O)cc(=O)o3)cccc2o1	InChI=1S/C18H16O5/c1-2-4-13-10-15(20)18-11(5-3-6-16(18)22-13)7-14-8-12(19)9-17(21)23-14/h3,5-6,8-10,19H,2,4,7H2,1H3	YZGLIUQOWSOKBY-UHFFFAOYSA-N	50241927	CHEMBL487191::Phaeochromycin C	MAP kinase-activated protein kinase 2	Homo sapiens		 130000							ChEMBL	10.1021/np0500629	10.7270/Q2BR8RXJ	16124774			Graziani, EI; Ritacco, FV; Bernan, VS; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50241927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50241927&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54697518	104098906		CHEMBL487191				ZINC14650433	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323776	COc1cc(ccc1NC(=O)c1cc2ccccc2n1C)-c1nn([C@H]2CC[C@@H](CC2)N2CCN(CC2)C(C)=O)c2ncnc(N)c12	InChI=1S/C34H39N9O3/c1-21(44)41-14-16-42(17-15-41)24-9-11-25(12-10-24)43-33-30(32(35)36-20-37-33)31(39-43)23-8-13-26(29(19-23)46-3)38-34(45)28-18-22-6-4-5-7-27(22)40(28)2/h4-8,13,18-20,24-25H,9-12,14-17H2,1-3H3,(H,38,45)(H2,35,36,37)/t24-,25-	ZMNWFTYYYCSSTF-SOAUALDESA-N	50175196	A-770041::CHEMBL197603::N-(4-(1-(4-(4-acetylpiperazin-1-yl)cyclohexyl)-4-amino-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2-carboxamide::N-(4-{1-[4-(4-ACETYLPIPERAZIN-1-YL)-TRANS-CYCLOHEXYL]-4-AMINO-1H-PYRAZOLO[3,4-D]PYRIMIDIN-3-YL}-2-METHOXYPHENYL)-1-METHYL-1H-INDOLE-2-CARBOXAMIDE	MAP kinase-activated protein kinase 2	Homo sapiens		>25000							ChEMBL	10.1016/j.bmcl.2005.09.039	10.7270/Q22F7N07	16216497			Burchat, A; Borhani, DW; Calderwood, DJ; Hirst, GC; Li, B; Stachlewitz, RF	Abbott Bioresearch Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175196	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175196&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	L2G	2C0O	9549184	104060935		CHEMBL197603				ZINC14210723	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323880	Cc1n[nH]c2sc(cc12)C(=O)NCc1ccccc1	InChI=1S/C14H13N3OS/c1-9-11-7-12(19-14(11)17-16-9)13(18)15-8-10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H,15,18)(H,16,17)	KASGWSVWRRHWBU-UHFFFAOYSA-N	50175243	CHEMBL373001::N-benzyl-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175243	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175243&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44405941	104060982		CHEMBL373001				ZINC28564935	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323883	O=C(NCCc1ccccc1)c1cc2c(n[nH]c2s1)-c1ccccc1	InChI=1S/C20H17N3OS/c24-19(21-12-11-14-7-3-1-4-8-14)17-13-16-18(22-23-20(16)25-17)15-9-5-2-6-10-15/h1-10,13H,11-12H2,(H,21,24)(H,22,23)	COQMBZDAQWGIGH-UHFFFAOYSA-N	50175234	CHEMBL197923::N-phenethyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175234	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175234&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44406013	104060973		CHEMBL197923				ZINC28565097	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323909	Cc1n[nH]c2sc(cc12)C(=O)NC1CCCCC1	InChI=1S/C13H17N3OS/c1-8-10-7-11(18-13(10)16-15-8)12(17)14-9-5-3-2-4-6-9/h7,9H,2-6H2,1H3,(H,14,17)(H,15,16)	SGCQJCPNXKHNPH-UHFFFAOYSA-N	50175240	CHEMBL199951::N-cyclohexyl-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175240	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175240&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44405940	104060979		CHEMBL199951				ZINC28564933	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323911	COc1ccc(CNC(=O)c2cc3c(n[nH]c3s2)-c2ccccc2)cc1	InChI=1S/C20H17N3O2S/c1-25-15-9-7-13(8-10-15)12-21-19(24)17-11-16-18(22-23-20(16)26-17)14-5-3-2-4-6-14/h2-11H,12H2,1H3,(H,21,24)(H,22,23)	OJLPXQRQXJPIKO-UHFFFAOYSA-N	50175241	CHEMBL199383::N-(4-methoxybenzyl)-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		 16000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175241	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175241&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44406014	104060980		CHEMBL199383				ZINC28564987	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323941	CN1CCN(CC1)C(=O)c1cc2c(n[nH]c2s1)-c1ccccc1	InChI=1S/C17H18N4OS/c1-20-7-9-21(10-8-20)17(22)14-11-13-15(18-19-16(13)23-14)12-5-3-2-4-6-12/h2-6,11H,7-10H2,1H3,(H,18,19)	UJXSEZDSHGPMOE-UHFFFAOYSA-N	50175232	(4-methylpiperazin-1-yl)(3-phenyl-1H-thieno[2,3-c]pyrazol-5-yl)methanone::CHEMBL371239	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175232	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175232&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44406018	104060971		CHEMBL371239				ZINC28565109	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323942	O=C(NCc1ccccc1)c1cc2c(n[nH]c2s1)-c1ccccc1	InChI=1S/C19H15N3OS/c23-18(20-12-13-7-3-1-4-8-13)16-11-15-17(21-22-19(15)24-16)14-9-5-2-6-10-14/h1-11H,12H2,(H,20,23)(H,21,22)	CNVFENCTUFMYBP-UHFFFAOYSA-N	50175247	CHEMBL200499::N-benzyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		 17000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175247	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175247&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11359538	104060986		CHEMBL200499				ZINC28564965	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323959	CCCCN(C)C(=O)c1cc2c(C)n[nH]c2s1	InChI=1S/C12H17N3OS/c1-4-5-6-15(3)12(16)10-7-9-8(2)13-14-11(9)17-10/h7H,4-6H2,1-3H3,(H,13,14)	ORWCFWCLFTZXTR-UHFFFAOYSA-N	50175242	CHEMBL200657::N-butyl-N,3-dimethyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175242	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175242&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44405939	104060981		CHEMBL200657				ZINC28564931	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323967	O=C(NC1CCCCC1)c1cc2c(n[nH]c2s1)-c1ccccc1	InChI=1S/C18H19N3OS/c22-17(19-13-9-5-2-6-10-13)15-11-14-16(20-21-18(14)23-15)12-7-3-1-4-8-12/h1,3-4,7-8,11,13H,2,5-6,9-10H2,(H,19,22)(H,20,21)	MLSDGZDBIVDXEE-UHFFFAOYSA-N	50175239	CHEMBL199755::N-cyclohexyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175239	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175239&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44406074	104060978		CHEMBL199755				ZINC28565132	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323973	CCCCNC(=O)c1cc2c(C)n[nH]c2s1	InChI=1S/C11H15N3OS/c1-3-4-5-12-10(15)9-6-8-7(2)13-14-11(8)16-9/h6H,3-5H2,1-2H3,(H,12,15)(H,13,14)	MNXLTLCOWQQAKN-UHFFFAOYSA-N	50175249	CHEMBL371242::N-butyl-3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175249	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175249&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44405938	104060988		CHEMBL371242				ZINC28564782	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50323992	CCCCN(C)C(=O)c1cc2c(n[nH]c2s1)-c1ccccc1	InChI=1S/C17H19N3OS/c1-3-4-10-20(2)17(21)14-11-13-15(18-19-16(13)22-14)12-8-6-5-7-9-12/h5-9,11H,3-4,10H2,1-2H3,(H,18,19)	DCRJMZNHTPDFNQ-UHFFFAOYSA-N	50175237	CHEMBL199528::N-butyl-N-methyl-3-phenyl-1H-thieno[2,3-c]pyrazole-5-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175237	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175237&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11645322	104060976		CHEMBL199528				ZINC28564943	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50324005	Cc1n[nH]c2sc(cc12)C(N)=O	InChI=1S/C7H7N3OS/c1-3-4-2-5(6(8)11)12-7(4)10-9-3/h2H,1H3,(H2,8,11)(H,9,10)	MELHJKUYOBXOER-UHFFFAOYSA-N	50175238	3-methyl-1H-thieno[2,3-c]pyrazole-5-carboxamide::CHEMBL198022	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2005.09.042	10.7270/Q2JH3KRS	16216502			Akritopoulou-Zanze, I; Darczak, D; Sarris, K; Phelan, KM; Huth, JR; Song, D; Johnson, EF; Jia, Y; Djuric, SW	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50175238	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50175238&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44405988	104060977		CHEMBL198022				ZINC28565047	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50361578	Nc1ncc(-c2cccc(c2)S(N)(=O)=O)c2scc(-c3ccc(F)c(Cl)c3)c12	InChI=1S/C19H13ClFN3O2S2/c20-15-7-11(4-5-16(15)21)14-9-27-18-13(8-24-19(22)17(14)18)10-2-1-3-12(6-10)28(23,25)26/h1-9H,(H2,22,24)(H2,23,25,26)	PILHXMMEJPSZLL-UHFFFAOYSA-N	50195879	3-(4-amino-3-(3-chloro-4-fluorophenyl)thieno[3,2-c]pyridin-7-yl)benzenesulfonamide::CHEMBL241517	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2006.09.050	10.7270/Q2SB45D5	17027260			Miyazaki, Y; Nakano, M; Sato, H; Truesdale, AT; Stuart, JD; Nartey, EN; Hightower, KE; Kane-Carson, L	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195879&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11281930	104077826		CHEMBL241517				ZINC28884841	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50361605	Nc1ncc(-c2cccc(c2)S(N)(=O)=O)c2occ(-c3ccc(NC(=O)Nc4cc(ccc4F)C(F)(F)F)cc3)c12	InChI=1S/C27H19F4N5O4S/c28-21-9-6-16(27(29,30)31)11-22(21)36-26(37)35-17-7-4-14(5-8-17)20-13-40-24-19(12-34-25(32)23(20)24)15-2-1-3-18(10-15)41(33,38)39/h1-13H,(H2,32,34)(H2,33,38,39)(H2,35,36,37)	CASSAPBDIVDPCC-UHFFFAOYSA-N	50195876	3-(4-amino-3-{4-[3-(2-fluoro-5-trifluoromethyl-phenyl)-ureido]-phenyl}-furo[3,2-c]pyridin-7-yl)-benzenesulfonamide::CHEMBL241682	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2006.09.050	10.7270/Q2SB45D5	17027260			Miyazaki, Y; Nakano, M; Sato, H; Truesdale, AT; Stuart, JD; Nartey, EN; Hightower, KE; Kane-Carson, L	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50195876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50195876&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9938299	104077823		CHEMBL241682				ZINC28884886	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50350864	Fc1cc(F)c(cc1NCc1cnc(Nc2ccccn2)s1)C(=O)NC1CC1	InChI=1S/C19H17F2N5OS/c20-14-8-15(21)16(7-13(14)18(27)25-11-4-5-11)23-9-12-10-24-19(28-12)26-17-3-1-2-6-22-17/h1-3,6-8,10-11,23H,4-5,9H2,(H,25,27)(H,22,24,26)	CUPLTRAPYIXFAX-UHFFFAOYSA-N	50189603	CHEMBL377734::N-cyclopropyl-2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5-yl)methylamino)benzamide	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1021/jm060347y	10.7270/Q2PG1RBM	16789733			Borzilleri, RM; Bhide, RS; Barrish, JC; D'Arienzo, CJ; Derbin, GM; Fargnoli, J; Hunt, JT; Jeyaseelan, R; Kamath, A; Kukral, DW; Marathe, P; Mortillo, S; Qian, L; Tokarski, JS; Wautlet, BS; Zheng, X; Lombardo, LJ	Bristol-Myers Squibb Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50189603	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50189603&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11632737	104073124		CHEMBL377734				ZINC34802943	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50374076	O[C@H]1CC[C@@H](CC1)NC(=O)c1ccc-2c(Cc3c(n[nH]c-23)-c2ccc(cc2)-c2ccc(O)cc2)c1	InChI=1S/C29H27N3O3/c33-23-10-5-18(6-11-23)17-1-3-19(4-2-17)27-26-16-21-15-20(7-14-25(21)28(26)32-31-27)29(35)30-22-8-12-24(34)13-9-22/h1-7,10-11,14-15,22,24,33-34H,8-9,12-13,16H2,(H,30,35)(H,31,32)/t22-,24-	VKPCXCHYSBVEMW-HCGLCNNCSA-N	50204694	3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL)-1,4-DIHYDROINDENO[1,2-C]PYRAZOLE-6-CARBOXAMIDE::3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,2-c]pyrazole-6-carboxylic acid (trans-4-hydroxycyclohexyl)-amide::3-(4'-hydroxybiphenyl-4-yl)-N-((1r,4r)-4-hydroxycyclohexyl)-1,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide::3-(4'-hydroxybiphenyl-4-yl)-N-(trans-4-hydroxycyclohexyl)-2,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide::CHEMBL438485	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmc.2007.01.012	10.7270/Q2XS5V22	17287122			Tong, Y; Claiborne, A; Stewart, KD; Park, C; Kovar, P; Chen, Z; Credo, RB; Gu, WZ; Gwaltney, SL; Judge, RA; Zhang, H; Rosenberg, SH; Sham, HL; Sowin, TJ; Lin, NH	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50204694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50204694&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	76A	2E9N	10050156	104083250		CHEMBL438485				ZINC28714095	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390169	COc1ccc2[nH]c3C(NC(C)Cc3c2c1)C(O)=O	InChI=1S/C14H16N2O3/c1-7-5-10-9-6-8(19-2)3-4-11(9)16-12(10)13(15-7)14(17)18/h3-4,6-7,13,15-16H,5H2,1-2H3,(H,17,18)	DTUVSOPBLDVLBG-UHFFFAOYSA-N	50215482	6-methoxy-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL247707	MAP kinase-activated protein kinase 2	Homo sapiens		 7100							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215482&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441140	104090076		CHEMBL247707				ZINC28948169	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390172	COc1ccc2[nH]c3C(N(Cc4ccccc4)CCc3c2c1)C(O)=O	InChI=1S/C20H20N2O3/c1-25-14-7-8-17-16(11-14)15-9-10-22(12-13-5-3-2-4-6-13)19(20(23)24)18(15)21-17/h2-8,11,19,21H,9-10,12H2,1H3,(H,23,24)	CLGPNUZMVDNNOW-UHFFFAOYSA-N	50215484	2-benzyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL248164	MAP kinase-activated protein kinase 2	Homo sapiens		 130000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215484&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441128	104090078		CHEMBL248164				ZINC28948095	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390173	COc1ccc2[nH]c3C(CO)NCCc3c2c1	InChI=1S/C13H16N2O2/c1-17-8-2-3-11-10(6-8)9-4-5-14-12(7-16)13(9)15-11/h2-3,6,12,14-16H,4-5,7H2,1H3	RAKVABWPDBXVLB-UHFFFAOYSA-N	50215486	(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)methanol::CHEMBL395133	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215486&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441131	104090080		CHEMBL395133				ZINC28948110	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390175	COc1ccc2n(C)c3C(NCCc3c2c1)C(O)=O	InChI=1S/C14H16N2O3/c1-16-11-4-3-8(19-2)7-10(11)9-5-6-15-12(13(9)16)14(17)18/h3-4,7,12,15H,5-6H2,1-2H3,(H,17,18)	NRPLCLTXPHCVMM-UHFFFAOYSA-N	50215487	6-methoxy-9-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL248512	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215487&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441135	104090081		CHEMBL248512				ZINC28948132	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390177	OC(=O)C1NCCc2c1[nH]c1ccc(O)cc21	InChI=1S/C12H12N2O3/c15-6-1-2-9-8(5-6)7-3-4-13-11(12(16)17)10(7)14-9/h1-2,5,11,13-15H,3-4H2,(H,16,17)	KDTKEEBTTHBVSR-UHFFFAOYSA-N	50215489	6-hydroxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL246099	MAP kinase-activated protein kinase 2	Homo sapiens		 4500							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215489&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			176962	104090083		CHEMBL246099				ZINC06094158	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390179	COc1ccc2[nH]c3C(NCCc3c2c1C)C(O)=O	InChI=1S/C14H16N2O3/c1-7-10(19-2)4-3-9-11(7)8-5-6-15-13(14(17)18)12(8)16-9/h3-4,13,15-16H,5-6H2,1-2H3,(H,17,18)	UIQKABTUCCDDMG-UHFFFAOYSA-N	50215490	6-methoxy-5-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL247344	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215490&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441115	104090084		CHEMBL247344				ZINC28948048	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390181	NC(=O)c1ccc2[nH]c3C(NCCc3c2c1)C(O)=O	InChI=1S/C13H13N3O3/c14-12(17)6-1-2-9-8(5-6)7-3-4-15-11(13(18)19)10(7)16-9/h1-2,5,11,15-16H,3-4H2,(H2,14,17)(H,18,19)	CZZFXDNDIRRHMO-UHFFFAOYSA-N	50215491	6-carbamoyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL246309	MAP kinase-activated protein kinase 2	Homo sapiens		 28000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215491&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441119	104090085		CHEMBL246309				ZINC28948065	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390182	COc1ccc2c3CCNC(C(O)=O)c3[nH]c2c1	InChI=1S/C13H14N2O3/c1-18-7-2-3-8-9-4-5-14-12(13(16)17)11(9)15-10(8)6-7/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	HVXBPEBYKAQAIV-UHFFFAOYSA-N	50215493	7-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL247342	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215493&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441112	104090087		CHEMBL247342				ZINC28948036	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390184	CCOC(=O)C1N2CCC(C2)c2c1[nH]c1ccc(OC)cc21	InChI=1S/C17H20N2O3/c1-3-22-17(20)16-15-14(10-6-7-19(16)9-10)12-8-11(21-2)4-5-13(12)18-15/h4-5,8,10,16,18H,3,6-7,9H2,1-2H3	RFZWVABYIIVIJU-UHFFFAOYSA-N	50215492	CHEMBL394125::ethyl 5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-2(10),3,5,7-tetraene-11-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		 29300							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215492&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441151	104090086		CHEMBL394125				ZINC40776029	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390186	COc1ccc2[nH]c3C(NC(Cc3c2c1)C(F)(F)F)C(O)=O	InChI=1S/C14H13F3N2O3/c1-22-6-2-3-9-7(4-6)8-5-10(14(15,16)17)19-12(13(20)21)11(8)18-9/h2-4,10,12,18-19H,5H2,1H3,(H,20,21)	HLJKZFNSLBKVMZ-UHFFFAOYSA-N	50215495	6-methoxy-3-(trifluoromethyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL397330	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215495&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441142	104090089		CHEMBL397330				ZINC28948188	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390188	COc1ccc2[nH]c3C(NC(CN(C)C)Cc3c2c1)C(O)=O	InChI=1S/C16H21N3O3/c1-19(2)8-9-6-12-11-7-10(22-3)4-5-13(11)18-14(12)15(17-9)16(20)21/h4-5,7,9,15,17-18H,6,8H2,1-3H3,(H,20,21)	MESXODUBVZGQCV-UHFFFAOYSA-N	50215494	3-((dimethylamino)methyl)-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL245461	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441146	104090088		CHEMBL245461				ZINC28948214	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390190	COc1ccc2[nH]c3c(nccc3c2c1)C(O)=O	InChI=1S/C13H10N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-6,15H,1H3,(H,16,17)	HIHIFVIUXJFFLO-UHFFFAOYSA-N	50215496	6-Methoxy-9H-beta-carboline-1-carboxylic acid::6-methoxy-9H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL280224	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215496&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44269421	104090090		CHEMBL280224				ZINC13587052	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390192	COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(=O)OCc1ccccc1	InChI=1S/C22H22N2O3/c1-26-16-7-8-18-17(11-16)19-15-9-10-24(12-15)21(20(19)23-18)22(25)27-13-14-5-3-2-4-6-14/h2-8,11,15,21,23H,9-10,12-13H2,1H3	GJRDOKLPYMRLFW-UHFFFAOYSA-N	50215485	CHEMBL245661::benzyl 5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-2(10),3,5,7-tetraene-11-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		 7090							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215485&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441152	104090079		CHEMBL245661				ZINC34804547	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390193	COC(=O)C1NCCc2c1[nH]c1ccc(OC)cc21	InChI=1S/C14H16N2O3/c1-18-8-3-4-11-10(7-8)9-5-6-15-13(12(9)16-11)14(17)19-2/h3-4,7,13,15-16H,5-6H2,1-2H3	SJRIQOGRDDWTOZ-UHFFFAOYSA-N	50215498	CHEMBL395132::methyl 6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		 47000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215498&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441129	104090092		CHEMBL395132				ZINC28948101	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390194	COc1ccc2[nH]c3C(NCCc3c2c1)C(N)=O	InChI=1S/C13H15N3O2/c1-18-7-2-3-10-9(6-7)8-4-5-15-12(13(14)17)11(8)16-10/h2-3,6,12,15-16H,4-5H2,1H3,(H2,14,17)	RKPJMNDWLLIELL-UHFFFAOYSA-N	50215500	6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxamide::CHEMBL245704	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215500&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441130	104090094		CHEMBL245704				ZINC28948107	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390196	COc1ccc2[nH]c3C(CC(O)=O)NCCc3c2c1	InChI=1S/C14H16N2O3/c1-19-8-2-3-11-10(6-8)9-4-5-15-12(7-13(17)18)14(9)16-11/h2-3,6,12,15-16H,4-5,7H2,1H3,(H,17,18)	WGEZCJVHMGEZOR-UHFFFAOYSA-N	50215505	2-(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)acetic acid::CHEMBL248511	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215505&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			4274924	104090099		CHEMBL248511				ZINC03155132	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390197	COc1ccc2[nH]c3C(NCC(C)c3c2c1)C(O)=O	InChI=1S/C14H16N2O3/c1-7-6-15-13(14(17)18)12-11(7)9-5-8(19-2)3-4-10(9)16-12/h3-5,7,13,15-16H,6H2,1-2H3,(H,17,18)	IGCZCYUOHYYYTG-UHFFFAOYSA-N	50215502	6-methoxy-4-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL248110	MAP kinase-activated protein kinase 2	Homo sapiens		 2200							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215502&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441136	104090096		CHEMBL248110				ZINC28948139	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390198	CCC1CNC(C(O)=O)c2[nH]c3ccc(OC)cc3c12	InChI=1S/C15H18N2O3/c1-3-8-7-16-14(15(18)19)13-12(8)10-6-9(20-2)4-5-11(10)17-13/h4-6,8,14,16-17H,3,7H2,1-2H3,(H,18,19)	DCTRZVSCCZUQGX-UHFFFAOYSA-N	50215503	4-ethyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL248316	MAP kinase-activated protein kinase 2	Homo sapiens		 2200							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215503&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441137	104090097		CHEMBL248316				ZINC28948148	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390199	OC(=O)C1NCCc2c1[nH]c1ccc(OCC(=O)c3ccccc3)cc21	InChI=1S/C20H18N2O4/c23-17(12-4-2-1-3-5-12)11-26-13-6-7-16-15(10-13)14-8-9-21-19(20(24)25)18(14)22-16/h1-7,10,19,21-22H,8-9,11H2,(H,24,25)	KXZSOVFOFVXVTM-UHFFFAOYSA-N	50215501	6-(2-oxo-2-phenyl-ethoxy)-2,3,4,9-tetrahydro-1H-beta-carboline-1-carboxylic acid::CHEMBL245296	MAP kinase-activated protein kinase 2	Homo sapiens		 1100							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215501&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441121	104090095		CHEMBL245296				ZINC28948073	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390200	COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(=O)OCC=C	InChI=1S/C18H20N2O3/c1-3-8-23-18(21)17-16-15(11-6-7-20(17)10-11)13-9-12(22-2)4-5-14(13)19-16/h3-5,9,11,17,19H,1,6-8,10H2,2H3	TVXIQDYFBFLLAC-UHFFFAOYSA-N	50215506	CHEMBL245862::prop-2-en-1-yl 5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-2(10),3,5,7-tetraene-11-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		 3270							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215506&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441155	104090100		CHEMBL245862				ZINC34804553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390201	COc1ccc2[nH]c3C(NCCc3c2c1)C(=O)NO	InChI=1S/C13H15N3O3/c1-19-7-2-3-10-9(6-7)8-4-5-14-12(11(8)15-10)13(17)16-18/h2-3,6,12,14-15,18H,4-5H2,1H3,(H,16,17)	SCXVVNHSRQFVBH-UHFFFAOYSA-N	50215499	CHEMBL248312::N-hydroxy-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		 88000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215499&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441133	104090093		CHEMBL248312				ZINC28948118	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390202	COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(=O)OC(C)c1ccccc1	InChI=1S/C23H24N2O3/c1-14(15-6-4-3-5-7-15)28-23(26)22-21-20(16-10-11-25(22)13-16)18-12-17(27-2)8-9-19(18)24-21/h3-9,12,14,16,22,24H,10-11,13H2,1-2H3	QOYBOGLFRNMXIM-UHFFFAOYSA-N	50215488	1-phenylethyl 5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-2(10),3,5,7-tetraene-11-carboxylate::CHEMBL395352	MAP kinase-activated protein kinase 2	Homo sapiens		 13000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215488&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441158	104090082		CHEMBL395352				ZINC40781692	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390205	COc1ccc2[nH]c3C(CCCc3c2c1)C(O)=O	InChI=1S/C14H15NO3/c1-18-8-5-6-12-11(7-8)9-3-2-4-10(14(16)17)13(9)15-12/h5-7,10,15H,2-4H2,1H3,(H,16,17)	LFQOVKSZZBTUJG-UHFFFAOYSA-N	50215507	6-methoxy-2,3,4,9-tetrahydro-1H-carbazole-1-carboxylic acid::CHEMBL245502	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215507&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			21399939	104090101		CHEMBL245502				ZINC11948696	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390206	CCCOC(=O)C1N2CCC(C2)c2c1[nH]c1ccc(OC)cc21	InChI=1S/C18H22N2O3/c1-3-8-23-18(21)17-16-15(11-6-7-20(17)10-11)13-9-12(22-2)4-5-14(13)19-16/h4-5,9,11,17,19H,3,6-8,10H2,1-2H3	PLLMARXCWGFAJQ-UHFFFAOYSA-N	50215504	CHEMBL245662::propyl 5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-2(10),3,5,7-tetraene-11-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		 10100							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215504&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			23661565	104090098		CHEMBL245662				ZINC40605935	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390207	OC(=O)C1NCCc2c1[nH]c1ccc(Cl)cc21	InChI=1S/C12H11ClN2O2/c13-6-1-2-9-8(5-6)7-3-4-14-11(12(16)17)10(7)15-9/h1-2,5,11,14-15H,3-4H2,(H,16,17)	CMQSGMXGIWWFHN-UHFFFAOYSA-N	50215511	6-chloro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL246102	MAP kinase-activated protein kinase 2	Homo sapiens		 19000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215511&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441118	104090105		CHEMBL246102				ZINC28948061	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390208	OC(=O)C1NCCc2c1[nH]c1ccc(F)cc21	InChI=1S/C12H11FN2O2/c13-6-1-2-9-8(5-6)7-3-4-14-11(12(16)17)10(7)15-9/h1-2,5,11,14-15H,3-4H2,(H,16,17)	VCTDIQKAMVWQFS-UHFFFAOYSA-N	50215512	6-fluoro-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL391830	MAP kinase-activated protein kinase 2	Homo sapiens		 26000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215512&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			12773710	104090106		CHEMBL391830				ZINC28948058	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390209	CCN1CCc2c([nH]c3ccc(OC)cc23)C1C(O)=O	InChI=1S/C15H18N2O3/c1-3-17-7-6-10-11-8-9(20-2)4-5-12(11)16-13(10)14(17)15(18)19/h4-5,8,14,16H,3,6-7H2,1-2H3,(H,18,19)	RZWSTRMPTUDUIU-UHFFFAOYSA-N	50215508	2-ethyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL245505	MAP kinase-activated protein kinase 2	Homo sapiens		 5800							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215508&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441126	104090102		CHEMBL245505				ZINC28948088	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390210	COc1ccc2[nH]c3C(OCCc3c2c1)C(O)=O	InChI=1S/C13H13NO4/c1-17-7-2-3-10-9(6-7)8-4-5-18-12(13(15)16)11(8)14-10/h2-3,6,12,14H,4-5H2,1H3,(H,15,16)	ZENNAQZPBNWPLL-UHFFFAOYSA-N	50215509	6-methoxy-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-carboxylic acid::CHEMBL245503	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215509&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441123	104090103		CHEMBL245503				ZINC28948079	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390211	COc1ccc2[nH]c3C(NC(CO)Cc3c2c1)C(O)=O	InChI=1S/C14H16N2O4/c1-20-8-2-3-11-9(5-8)10-4-7(6-17)15-13(14(18)19)12(10)16-11/h2-3,5,7,13,15-17H,4,6H2,1H3,(H,18,19)	KVSKWDSWCLDDMU-UHFFFAOYSA-N	50215510	3-(hydroxymethyl)-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL392665	MAP kinase-activated protein kinase 2	Homo sapiens		 3000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215510&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441143	104090104		CHEMBL392665				ZINC28948195	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390212	OC(=O)C1NCCc2c1[nH]c1ccccc21	InChI=1S/C12H12N2O2/c15-12(16)11-10-8(5-6-13-11)7-3-1-2-4-9(7)14-10/h1-4,11,13-14H,5-6H2,(H,15,16)	XGCIVVYTCDKDLC-UHFFFAOYSA-N	50215516	2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL246101	MAP kinase-activated protein kinase 2	Homo sapiens		 87000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215516&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			145879	104090110		CHEMBL246101				ZINC00038350	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390213	COc1ccc2[nH]c3C(CN)NCCc3c2c1	InChI=1S/C13H17N3O/c1-17-8-2-3-11-10(6-8)9-4-5-15-12(7-14)13(9)16-11/h2-3,6,12,15-16H,4-5,7,14H2,1H3	VGUFUCJGTJBSQU-UHFFFAOYSA-N	50215514	(6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)methanamine::CHEMBL245705	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215514&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441132	104090108		CHEMBL245705				ZINC28948114	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390214	CC(=O)Oc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O	InChI=1S/C14H14N2O4/c1-7(17)20-8-2-3-11-10(6-8)9-4-5-15-13(14(18)19)12(9)16-11/h2-3,6,13,15-16H,4-5H2,1H3,(H,18,19)	SRJUZPVSILDPCI-UHFFFAOYSA-N	50215515	6-acetoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL437554	MAP kinase-activated protein kinase 2	Homo sapiens		 170000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215515&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441117	104090109		CHEMBL437554				ZINC28948055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390215	COc1cccc2c3CCNC(C(O)=O)c3[nH]c12	InChI=1S/C13H14N2O3/c1-18-9-4-2-3-7-8-5-6-14-12(13(16)17)11(8)15-10(7)9/h2-4,12,14-15H,5-6H2,1H3,(H,16,17)	DQLQUXWGVFYHBF-UHFFFAOYSA-N	50215519	8-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL395409	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215519&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441113	104090113		CHEMBL395409				ZINC28948040	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390216	COC(=O)c1nccc2c3cc(OC)ccc3[nH]c12	InChI=1S/C14H12N2O3/c1-18-8-3-4-11-10(7-8)9-5-6-15-13(12(9)16-11)14(17)19-2/h3-7,16H,1-2H3	XWJJYUDWDGAUPR-UHFFFAOYSA-N	50215518	CHEMBL396163::methyl 6-methoxy-9H-pyrido[3,4-b]indole-1-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215518&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441122	104090112		CHEMBL396163				ZINC28948075	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390217	OC(=O)C1NCCc2c1[nH]c1ccc(OCc3ccccc3)cc21	InChI=1S/C19H18N2O3/c22-19(23)18-17-14(8-9-20-18)15-10-13(6-7-16(15)21-17)24-11-12-4-2-1-3-5-12/h1-7,10,18,20-21H,8-9,11H2,(H,22,23)	MYJRDKWIBPANCM-UHFFFAOYSA-N	50215513	6-(benzyloxy)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL396314	MAP kinase-activated protein kinase 2	Homo sapiens		 12000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215513&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441120	104090107		CHEMBL396314				ZINC28948069	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390218	COc1ccc2[nH]c3C(N4CCCC(C4)c3c2c1)C(O)=O	InChI=1S/C16H18N2O3/c1-21-10-4-5-12-11(7-10)13-9-3-2-6-18(8-9)15(16(19)20)14(13)17-12/h4-5,7,9,15,17H,2-3,6,8H2,1H3,(H,19,20)	BDRAYCVSLZSFNY-UHFFFAOYSA-N	50215497	5-methoxy-9,12-diazatetracyclo[10.3.1.0^{2,10}.0^{3,8}]hexadeca-2(10),3,5,7-tetraene-11-carboxylic acid::CHEMBL394124	MAP kinase-activated protein kinase 2	Homo sapiens		 5100							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215497&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441149	104090091		CHEMBL394124				ZINC34804540	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390219	COc1ccc2[nH]c3C(N4CCC(C4)c3c2c1)C(O)=O	InChI=1S/C15H16N2O3/c1-20-9-2-3-11-10(6-9)12-8-4-5-17(7-8)14(15(18)19)13(12)16-11/h2-3,6,8,14,16H,4-5,7H2,1H3,(H,18,19)	YRWZXBDQPAUWNA-UHFFFAOYSA-N	50215481	5-methoxy-9,12-diazatetracyclo[10.2.1.0^{2,10}.0^{3,8}]pentadeca-2(10),3,5,7-tetraene-11-carboxylic acid::CHEMBL392876	MAP kinase-activated protein kinase 2	Homo sapiens		 290							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215481&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			23661564	104090075		CHEMBL392876				ZINC34804535	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390220	COc1cccc2[nH]c3C(NCCc3c12)C(O)=O	InChI=1S/C13H14N2O3/c1-18-9-4-2-3-8-10(9)7-5-6-14-12(13(16)17)11(7)15-8/h2-4,12,14-15H,5-6H2,1H3,(H,16,17)	DRQGUKDLNGJXQY-UHFFFAOYSA-N	50215522	5-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL247138	MAP kinase-activated protein kinase 2	Homo sapiens		 42000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215522&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			17881612	104090116		CHEMBL247138				ZINC28948032	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390222	COc1ccc2[nH]c3C(NCCc3c2c1)c1nnn[nH]1	InChI=1S/C13H14N6O/c1-20-7-2-3-10-9(6-7)8-4-5-14-12(11(8)15-10)13-16-18-19-17-13/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17,18,19)	YWNLRZBLSYMZRG-UHFFFAOYSA-N	50215521	6-methoxy-1-(2H-tetrazol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole::CHEMBL248313	MAP kinase-activated protein kinase 2	Homo sapiens		 130000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215521&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441134	104090115		CHEMBL248313				ZINC28948123	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390223	COc1ccc2[nH]c3C(NCCc3c2c1)C(O)=O	InChI=1S/C13H14N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)	GHEBCEHFQAHKRP-UHFFFAOYSA-N	50215483	6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL395157	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215483&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			3848929	104090077		CHEMBL395157				ZINC00120368	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390224	COc1ccc2[nH]c3C(N(C)CCc3c2c1)C(O)=O	InChI=1S/C14H16N2O3/c1-16-6-5-9-10-7-8(19-2)3-4-11(10)15-12(9)13(16)14(17)18/h3-4,7,13,15H,5-6H2,1-2H3,(H,17,18)	LWNPZWRKYQSJQW-UHFFFAOYSA-N	50215517	6-methoxy-2-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL397649	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215517&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441124	104090111		CHEMBL397649				ZINC28948082	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390225	COC(=O)c1ccc2[nH]c3C(NCCc3c2c1)C(O)=O	InChI=1S/C14H14N2O4/c1-20-14(19)7-2-3-10-9(6-7)8-4-5-15-12(13(17)18)11(8)16-10/h2-3,6,12,15-16H,4-5H2,1H3,(H,17,18)	VRMZLVYUAXEGCT-UHFFFAOYSA-N	50215520	6-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL246100	MAP kinase-activated protein kinase 2	Homo sapiens		 6600							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215520&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441116	104090114		CHEMBL246100				ZINC28948051	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390226	COc1ccc2[nH]c3C(NC(CN)Cc3c2c1)C(O)=O	InChI=1S/C14H17N3O3/c1-20-8-2-3-11-9(5-8)10-4-7(6-15)16-13(14(18)19)12(10)17-11/h2-3,5,7,13,16-17H,4,6,15H2,1H3,(H,18,19)	YBHDENBEEJTMON-UHFFFAOYSA-N	50215523	3-(aminomethyl)-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL248525	MAP kinase-activated protein kinase 2	Homo sapiens		 5900							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215523&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441144	104090117		CHEMBL248525				ZINC28948203	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390227	COc1cc2c3CCNC(C(O)=O)c3[nH]c2cc1O	InChI=1S/C13H14N2O4/c1-19-10-4-7-6-2-3-14-12(13(17)18)11(6)15-8(7)5-9(10)16/h4-5,12,14-16H,2-3H2,1H3,(H,17,18)	IYQLUTFBWWAEID-UHFFFAOYSA-N	50215525	7-hydroxy-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL247343	MAP kinase-activated protein kinase 2	Homo sapiens		 53000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215525&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441114	104090119		CHEMBL247343				ZINC28948044	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390228	COc1ccc2[nH]c3C(N(CCc3c2c1)C(C)C)C(O)=O	InChI=1S/C16H20N2O3/c1-9(2)18-7-6-11-12-8-10(21-3)4-5-13(12)17-14(11)15(18)16(19)20/h4-5,8-9,15,17H,6-7H2,1-3H3,(H,19,20)	XXOITNYOVMAEAC-UHFFFAOYSA-N	50215527	2-isopropyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL437766	MAP kinase-activated protein kinase 2	Homo sapiens		 170000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215527&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441127	104090121		CHEMBL437766				ZINC28948091	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390229	COc1ccc2[nH]c3c(CCNC3(C)C(O)=O)c2c1	InChI=1S/C14H16N2O3/c1-14(13(17)18)12-9(5-6-15-14)10-7-8(19-2)3-4-11(10)16-12/h3-4,7,15-16H,5-6H2,1-2H3,(H,17,18)	BETCVGLWCYMGME-UHFFFAOYSA-N	50215526	6-methoxy-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL396151	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215526&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			612268	104090120		CHEMBL396151				ZINC28948128	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390230	CCC1Cc2c([nH]c3ccc(OC)cc23)C(N1)C(O)=O	InChI=1S/C15H18N2O3/c1-3-8-6-11-10-7-9(20-2)4-5-12(10)17-13(11)14(16-8)15(18)19/h4-5,7-8,14,16-17H,3,6H2,1-2H3,(H,18,19)	XYWKVJOWOSIIEX-UHFFFAOYSA-N	50215528	3-ethyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL247911	MAP kinase-activated protein kinase 2	Homo sapiens		 64000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215528&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441141	104090122		CHEMBL247911				ZINC28948176	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50390231	COc1ccc2[nH]c3C(NCC(Cc4ccccc4)c3c2c1)C(O)=O	InChI=1S/C20H20N2O3/c1-25-14-7-8-16-15(10-14)17-13(9-12-5-3-2-4-6-12)11-21-19(20(23)24)18(17)22-16/h2-8,10,13,19,21-22H,9,11H2,1H3,(H,23,24)	VIDXROHEPRSMEA-UHFFFAOYSA-N	50215524	4-benzyl-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid::CHEMBL248317	MAP kinase-activated protein kinase 2	Homo sapiens		 16000							ChEMBL	10.1016/j.bmcl.2007.05.070	10.7270/Q2PR7VPC	17570666			Trujillo, JI; Meyers, MJ; Anderson, DR; Hegde, S; Mahoney, MW; Vernier, WF; Buchler, IP; Wu, KK; Yang, S; Yang, S; Hartmann, SJ; Reitz, DB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50215524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50215524&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44441139	104090118		CHEMBL248317				ZINC28948158	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50399488	Fc1ccc(Nc2c(cnc3c(Cl)cc(NCc4cnc[nH]4)cc23)C#N)cc1Cl	InChI=1S/C20H13Cl2FN6/c21-16-4-12(1-2-18(16)23)29-19-11(6-24)7-27-20-15(19)3-13(5-17(20)22)26-9-14-8-25-10-28-14/h1-5,7-8,10,26H,9H2,(H,25,28)(H,27,29)	ONXROKMQGCSOMG-UHFFFAOYSA-N	21898	8-chloro-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol-4-ylmethyl)amino]quinoline-3-carbonitrile::CHEMBL436817::Cyanoquinoline, 11	MAP kinase-activated protein kinase 2	Homo sapiens		 48000							ChEMBL	10.1074/jbc.M703694200	10.7270/Q2KS6RBP	17848581			Hall, JP; Kurdi, Y; Hsu, S; Cuozzo, J; Liu, J; Telliez, JB; Seidl, KJ; Winkler, A; Hu, Y; Green, N; Askew, GR; Tam, S; Clark, JD; Lin, LL	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21898	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21898&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			17759555	49701002		CHEMBL436817				ZINC14977346	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50398771	NC(=O)c1cc(F)cc2CN(C3CCN(CC3)C3CCC(F)(F)CC3)C(=O)c12	InChI=1S/C20H24F3N3O2/c21-13-9-12-11-26(19(28)17(12)16(10-13)18(24)27)15-3-7-25(8-4-15)14-1-5-20(22,23)6-2-14/h9-10,14-15H,1-8,11H2,(H2,24,27)	ARYVAQSYRLZVQD-UHFFFAOYSA-N	138348	US8877944, 99	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.5b00680	10.7270/Q2JD4ZKF	26222319			Papeo, G; Posteri, H; Borghi, D; Busel, AA; Caprera, F; Casale, E; Ciomei, M; Cirla, A; Corti, E; D'Anello, M; Fasolini, M; Forte, B; Galvani, A; Isacchi, A; Khvat, A; Krasavin, MY; Lupi, R; Orsini, P; Perego, R; Pesenti, E; Pezzetta, D; Rainoldi, S; Riccardi-Sirtori, F; Scolaro, A; Sola, F; Zuccotto, F; Felder, ER; Donati, D; Montagnoli, A	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=138348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=138348&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	D7N	4ZZY,5A00	49843531	249815573							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50411131	NC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1	InChI=1S/C27H27F2N7O3/c28-19-3-1-17(2-4-19)13-24(37)34-27(38)33-21-5-6-23(22(29)14-21)39-26-25-18(7-12-36(25)32-16-31-26)15-35-10-8-20(30)9-11-35/h1-7,12,14,16,20H,8-11,13,15,30H2,(H2,33,34,37,38)	YQQFRBUHZZNTGY-UHFFFAOYSA-N	50235544	1-(4-(5-((4-aminopiperidin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-yloxy)-3-fluorophenyl)-3-(2-(4-fluorophenyl)acetyl)urea::CHEMBL253881::N-{[4-({5-[(4-aminopiperidin-1-yl)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-yl}oxy)-3-fluorophenyl]carbamoyl}-2-(4-fluorophenyl)acetamide	MAP kinase-activated protein kinase 2	Homo sapiens		>5000							ChEMBL	10.1016/j.bmcl.2008.01.121	10.7270/Q2125SFV	18289854			Schroeder, GM; Chen, XT; Williams, DK; Nirschl, DS; Cai, ZW; Wei, D; Tokarski, JS; An, Y; Sack, J; Chen, Z; Huynh, T; Vaccaro, W; Poss, M; Wautlet, B; Gullo-Brown, J; Kellar, K; Manne, V; Hunt, JT; Wong, TW; Lombardo, LJ; Fargnoli, J; Borzilleri, RM	Bristol-Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50235544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50235544&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	CKK	3C1X	21081523	104056093		CHEMBL253881				ZINC24970265	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50404809	Nc1nc2Oc3cc(O)c(O)cc3Cc2c(N)c1C#N	InChI=1S/C13H10N4O3/c14-4-7-11(15)6-1-5-2-8(18)9(19)3-10(5)20-13(6)17-12(7)16/h2-3,18-19H,1H2,(H4,15,16,17)	XIQLPJBFPQIUDK-UHFFFAOYSA-N	50225787	2,4-diamino-6,7-dihydroxy-10H-9-oxa-1-aza-anthracene-3-carbonitrile; TFA::CHEMBL1185204::CHEMBL397819	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2007.10.036	10.7270/Q2W095P4	17964780			Davis, T; Bagley, MC; Dix, MC; Murziani, PG; Rokicki, MJ; Widdowson, CS; Zayed, JM; Bachler, MA; Kipling, D	Cardiff University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225787	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225787&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9821424	104096860		CHEMBL1185204CHEMBL397819				ZINC28824806	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50422644	Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12	InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	CRPUDAVZTZIKMJ-QPJJXVBHSA-N	50263132	4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile::CHEMBL477817	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2008.06.040	10.7270/Q2WS8T2G	18606543			Nathan Tumey, L; Boschelli, DH; Lee, J; Chaudhary, D	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50263132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50263132&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24766030	104111594		CHEMBL477817				ZINC40412843	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50430448	Oc1cccc2cnccc12	InChI=1S/C9H7NO/c11-9-3-1-2-7-6-10-5-4-8(7)9/h1-6,11H	CSNXUYRHPXGSJD-UHFFFAOYSA-N	50240538	CHEMBL57481::Isoquinolin-5-ol	MAP kinase-activated protein kinase 2	Homo sapiens		 85000							ChEMBL	10.1021/jm800747w	10.7270/Q2JM29GJ	18771253			Constantine, KL; Mueller, L; Metzler, WJ; McDonnell, PA; Todderud, G; Goldfarb, V; Fan, Y; Newitt, JA; Kiefer, SE; Gao, M; Tortolani, D; Vaccaro, W; Tokarski, J	Bristol Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50240538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50240538&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	5SG	5EWH	30386	104098352		CHEMBL57481				ZINC00404427	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50430449	O=C1NCCc2[nH]c(cc12)-c1ccnc(\C=C\c2ccccc2)c1	InChI=1S/C20H17N3O/c24-20-17-13-19(23-18(17)9-11-22-20)15-8-10-21-16(12-15)7-6-14-4-2-1-3-5-14/h1-8,10,12-13,23H,9,11H2,(H,22,24)/b7-6+	RJZDECGDCKOHBV-VOTSOKGWSA-N	50253633	2-(2-styrylpyridin-4-yl)-6,7-dihydro-1H-pyrrolo[3,2-c]pyridin-4(5H)-one::CHEMBL510545	MAP kinase-activated protein kinase 2	Homo sapiens		 49							ChEMBL	10.1021/jm800747w	10.7270/Q2JM29GJ	18771253			Constantine, KL; Mueller, L; Metzler, WJ; McDonnell, PA; Todderud, G; Goldfarb, V; Fan, Y; Newitt, JA; Kiefer, SE; Gao, M; Tortolani, D; Vaccaro, W; Tokarski, J	Bristol Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50253633&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10313607	104106113		CHEMBL510545				ZINC38482297	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50430450	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cnc2ccccc2c1	InChI=1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)	OWFLADWRSCINST-UHFFFAOYSA-N	30185	CHEMBL226403::Pyrrolopyridine, 16	MAP kinase-activated protein kinase 2	Homo sapiens		 8.5							ChEMBL	10.1021/jm800747w	10.7270/Q2JM29GJ	18771253			Constantine, KL; Mueller, L; Metzler, WJ; McDonnell, PA; Todderud, G; Goldfarb, V; Fan, Y; Newitt, JA; Kiefer, SE; Gao, M; Tortolani, D; Vaccaro, W; Tokarski, J	Bristol Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30185&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P4O	2JBP,3GOK,3FHR,2JBO,3R2Y,7NRB	10389239	85147945		CHEMBL226403	DB08358			ZINC16052855	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50430451	Oc1cccc2ccccc12	InChI=1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H	KJCVRFUGPWSIIH-UHFFFAOYSA-N	23450	1-Naphthalenol::1-Naphthol::CHEMBL122617::Naphth-1-ol, 9::alpha-naphthol::naphthalen-1-ol	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm800747w	10.7270/Q2JM29GJ	18771253			Constantine, KL; Mueller, L; Metzler, WJ; McDonnell, PA; Todderud, G; Goldfarb, V; Fan, Y; Newitt, JA; Kiefer, SE; Gao, M; Tortolani, D; Vaccaro, W; Tokarski, J	Bristol Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=23450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=23450&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	1NP	7NNY,2ZVQ,7ZY5,6EKX,6EKY,4B33	7005	50091713	51138	CHEMBL122617			C11714	ZINC04292977	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429433	Nc1ncc(Cl)nc1CNC(=O)Nc1ccc(cc1)N(C(=O)c1ccccc1)c1ccccc1	InChI=1S/C25H21ClN6O2/c26-22-16-28-23(27)21(31-22)15-29-25(34)30-18-11-13-20(14-12-18)32(19-9-5-2-6-10-19)24(33)17-7-3-1-4-8-17/h1-14,16H,15H2,(H2,27,28)(H2,29,30,34)	TXIIAOIUVITEJC-UHFFFAOYSA-N	50127667	CHEMBL3629334	MAP kinase-activated protein kinase 2	Homo sapiens		 14500							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127667	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127667&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194215	321902601		CHEMBL3629334					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429434	Nc1ncc(nc1CNC(=O)Nc1ccc(cc1)N(C(=O)c1ccccc1)c1ccccc1)C1CC1	InChI=1S/C28H26N6O2/c29-26-25(33-24(17-30-26)19-11-12-19)18-31-28(36)32-21-13-15-23(16-14-21)34(22-9-5-2-6-10-22)27(35)20-7-3-1-4-8-20/h1-10,13-17,19H,11-12,18H2,(H2,29,30)(H2,31,32,36)	ILWJRPMCZWTTKF-UHFFFAOYSA-N	50127668	CHEMBL3629333	MAP kinase-activated protein kinase 2	Homo sapiens		 16200							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127668	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127668&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194214	321902602		CHEMBL3629333					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429626	CCCc1cnc(N)c(CNC(=O)Nc2ccccc2Cl)n1	InChI=1S/C15H18ClN5O/c1-2-5-10-8-18-14(17)13(20-10)9-19-15(22)21-12-7-4-3-6-11(12)16/h3-4,6-8H,2,5,9H2,1H3,(H2,17,18)(H2,19,21,22)	LNIXLGLODRSESM-UHFFFAOYSA-N	50127669	CHEMBL3629332	MAP kinase-activated protein kinase 2	Homo sapiens		 19000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127669	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127669&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194213	321902603		CHEMBL3629332					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429627	CCCc1cnc(N)c(CNC(=O)Nc2ccc(cc2)N(C(=O)c2ccccc2)c2ccccc2)n1	InChI=1S/C28H28N6O2/c1-2-9-22-18-30-26(29)25(32-22)19-31-28(36)33-21-14-16-24(17-15-21)34(23-12-7-4-8-13-23)27(35)20-10-5-3-6-11-20/h3-8,10-18H,2,9,19H2,1H3,(H2,29,30)(H2,31,33,36)	HWQIJOHSRCTRBK-UHFFFAOYSA-N	50127670	CHEMBL3629331	MAP kinase-activated protein kinase 2	Homo sapiens		 20000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127670	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127670&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194212	321902604		CHEMBL3629331					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429628	CCCc1cnc(N)c(CNC(=O)Nc2ccc(NC(=O)OCc3ccccc3)cc2)n1	InChI=1S/C23H26N6O3/c1-2-6-19-13-25-21(24)20(27-19)14-26-22(30)28-17-9-11-18(12-10-17)29-23(31)32-15-16-7-4-3-5-8-16/h3-5,7-13H,2,6,14-15H2,1H3,(H2,24,25)(H,29,31)(H2,26,28,30)	AULVFNOBRXHQKC-UHFFFAOYSA-N	50127671	CHEMBL3629330	MAP kinase-activated protein kinase 2	Homo sapiens		 8000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127671	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127671&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194211	321902605		CHEMBL3629330					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429629	CCCc1cnc(N)c(CNC(=O)Nc2ccc(NC(=O)OC)cc2)n1	InChI=1S/C17H22N6O3/c1-3-4-13-9-19-15(18)14(21-13)10-20-16(24)22-11-5-7-12(8-6-11)23-17(25)26-2/h5-9H,3-4,10H2,1-2H3,(H2,18,19)(H,23,25)(H2,20,22,24)	HCZMRLWHKKHZOF-UHFFFAOYSA-N	50127672	CHEMBL3629329	MAP kinase-activated protein kinase 2	Homo sapiens		 11800							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127672	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127672&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194210	321902606		CHEMBL3629329					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429630	CCCc1cnc(N)c(CNC(=O)Nc2ccc(NC(=O)Nc3ccccc3)cc2)n1	InChI=1S/C22H25N7O2/c1-2-6-18-13-24-20(23)19(26-18)14-25-21(30)27-16-9-11-17(12-10-16)29-22(31)28-15-7-4-3-5-8-15/h3-5,7-13H,2,6,14H2,1H3,(H2,23,24)(H2,25,27,30)(H2,28,29,31)	MDKVCJIYHPCGLG-UHFFFAOYSA-N	50127673	CHEMBL3629328	MAP kinase-activated protein kinase 2	Homo sapiens		 19000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127673&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194209	321902607		CHEMBL3629328					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429631	CCCc1cnc(N)c(CNC(=O)Nc2ccc(OC(=O)OC(C)(C)C)cc2)n1	InChI=1S/C20H27N5O4/c1-5-6-14-11-22-17(21)16(24-14)12-23-18(26)25-13-7-9-15(10-8-13)28-19(27)29-20(2,3)4/h7-11H,5-6,12H2,1-4H3,(H2,21,22)(H2,23,25,26)	PXWJOMRZSGEMDN-UHFFFAOYSA-N	50127674	CHEMBL3629327	MAP kinase-activated protein kinase 2	Homo sapiens		 11000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127674	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127674&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194208	321902608		CHEMBL3629327					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429632	CCCc1cnc(N)c(CNC(=O)Nc2ccc(NC(=O)OC(C)(C)C)cc2)n1	InChI=1S/C20H28N6O3/c1-5-6-15-11-22-17(21)16(24-15)12-23-18(27)25-13-7-9-14(10-8-13)26-19(28)29-20(2,3)4/h7-11H,5-6,12H2,1-4H3,(H2,21,22)(H,26,28)(H2,23,25,27)	RSUFAXFNHNJFQK-UHFFFAOYSA-N	50127675	CHEMBL3629326	MAP kinase-activated protein kinase 2	Homo sapiens		 6700							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127675&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194207	321902609		CHEMBL3629326					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429633	CCCc1cnc(N)c(CNC(=O)Nc2ccc3[nH]c(=O)oc3c2)n1	InChI=1S/C16H18N6O3/c1-2-3-10-7-18-14(17)12(20-10)8-19-15(23)21-9-4-5-11-13(6-9)25-16(24)22-11/h4-7H,2-3,8H2,1H3,(H2,17,18)(H,22,24)(H2,19,21,23)	PUZYXJOZGPCZLV-UHFFFAOYSA-N	50127676	CHEMBL3629325	MAP kinase-activated protein kinase 2	Homo sapiens		 750							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127676&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194206	321902610		CHEMBL3629325					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429634	Nc1ncc(nc1CNC(=O)Nc1ccc2[nH]c(=O)oc2c1)C1CC1	InChI=1S/C16H16N6O3/c17-14-12(21-11(6-18-14)8-1-2-8)7-19-15(23)20-9-3-4-10-13(5-9)25-16(24)22-10/h3-6,8H,1-2,7H2,(H2,17,18)(H,22,24)(H2,19,20,23)	HCIBULBZMPTKQO-UHFFFAOYSA-N	50127677	CHEMBL3629324	MAP kinase-activated protein kinase 2	Homo sapiens		 2200							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127677	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127677&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194205	321902611		CHEMBL3629324					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429635	Nc1ncc(Cl)nc1CNC(=O)Nc1ccc2[nH]c(=O)oc2c1	InChI=1S/C13H11ClN6O3/c14-10-5-16-11(15)8(19-10)4-17-12(21)18-6-1-2-7-9(3-6)23-13(22)20-7/h1-3,5H,4H2,(H2,15,16)(H,20,22)(H2,17,18,21)	GCDWFURQXDBRHS-UHFFFAOYSA-N	50127678	CHEMBL3629323	MAP kinase-activated protein kinase 2	Homo sapiens		 4500							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127678&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194204	321902612		CHEMBL3629323					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429636	CC(C)(C)OC(=O)Nc1ccc(NC(=O)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C17H21ClN6O3/c1-17(2,3)27-16(26)23-11-6-4-10(5-7-11)22-15(25)21-8-12-14(19)20-9-13(18)24-12/h4-7,9H,8H2,1-3H3,(H2,19,20)(H,23,26)(H2,21,22,25)	IGUQAVVGGTUNQG-UHFFFAOYSA-N	50127679	CHEMBL3629322	MAP kinase-activated protein kinase 2	Homo sapiens		 32000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127679&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194203	321902613		CHEMBL3629322					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429637	CCCc1cnc(N)c(CN\C(Nc2ccc3[nH]c(=O)oc3c2)=N/C(=O)c2ccccc2)n1	InChI=1S/C23H23N7O3/c1-2-6-16-12-25-20(24)18(27-16)13-26-22(30-21(31)14-7-4-3-5-8-14)28-15-9-10-17-19(11-15)33-23(32)29-17/h3-5,7-12H,2,6,13H2,1H3,(H2,24,25)(H,29,32)(H2,26,28,30,31)	TYVMBANLUDFYSH-UHFFFAOYSA-N	50127680	CHEMBL3629155	MAP kinase-activated protein kinase 2	Homo sapiens		 8000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127680&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194073	321902614		CHEMBL3629155					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429638	COc1ccc(cc1)C(=O)\N=C(/NCc1nc(cnc1N)C1CC1)Nc1ccc2[nH]c(=O)oc2c1	InChI=1S/C24H23N7O4/c1-34-16-7-4-14(5-8-16)22(32)31-23(28-15-6-9-17-20(10-15)35-24(33)30-17)27-12-19-21(25)26-11-18(29-19)13-2-3-13/h4-11,13H,2-3,12H2,1H3,(H2,25,26)(H,30,33)(H2,27,28,31,32)	UCWNBLQIZGARNK-UHFFFAOYSA-N	50127681	CHEMBL3629154	MAP kinase-activated protein kinase 2	Homo sapiens		 10000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127681&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194072	321902615		CHEMBL3629154					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429639	Nc1ncc(nc1CN\C(Nc1ccc2[nH]c(=O)oc2c1)=N/C(=O)c1ccc(Cl)cc1)C1CC1	InChI=1S/C23H20ClN7O3/c24-14-5-3-13(4-6-14)21(32)31-22(28-15-7-8-16-19(9-15)34-23(33)30-16)27-11-18-20(25)26-10-17(29-18)12-1-2-12/h3-10,12H,1-2,11H2,(H2,25,26)(H,30,33)(H2,27,28,31,32)	KIWJXOXYQFQNQS-UHFFFAOYSA-N	50127682	CHEMBL3629153	MAP kinase-activated protein kinase 2	Homo sapiens		 1900							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127682&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194071	321902616		CHEMBL3629153					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429640	Cc1ccc(cc1)C(=O)\N=C(/NCc1nc(cnc1N)C1CC1)Nc1ccc2[nH]c(=O)oc2c1	InChI=1S/C24H23N7O3/c1-13-2-4-15(5-3-13)22(32)31-23(28-16-8-9-17-20(10-16)34-24(33)30-17)27-12-19-21(25)26-11-18(29-19)14-6-7-14/h2-5,8-11,14H,6-7,12H2,1H3,(H2,25,26)(H,30,33)(H2,27,28,31,32)	HURMRSSQGFVMFK-UHFFFAOYSA-N	50127683	CHEMBL3629152	MAP kinase-activated protein kinase 2	Homo sapiens		 2400							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127683&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194070	321902617		CHEMBL3629152					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429641	CCOC(=O)\N=C(/NCc1nc(cnc1N)C1CC1)Nc1ccc2[nH]c(=O)oc2c1	InChI=1S/C19H21N7O4/c1-2-29-18(27)26-17(23-11-5-6-12-15(7-11)30-19(28)25-12)22-9-14-16(20)21-8-13(24-14)10-3-4-10/h5-8,10H,2-4,9H2,1H3,(H2,20,21)(H,25,28)(H2,22,23,26,27)	NWKDCIRLXNUAMQ-UHFFFAOYSA-N	50127684	CHEMBL3629151	MAP kinase-activated protein kinase 2	Homo sapiens		 7800							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127684&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194069	321902618		CHEMBL3629151					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429642	CC(C)(C)OC(=O)Nc1ccc(N\C(NCc2nc(Cl)cnc2N)=N\C(=O)c2ccccc2)cc1	InChI=1S/C24H26ClN7O3/c1-24(2,3)35-23(34)30-17-11-9-16(10-12-17)29-22(32-21(33)15-7-5-4-6-8-15)28-13-18-20(26)27-14-19(25)31-18/h4-12,14H,13H2,1-3H3,(H2,26,27)(H,30,34)(H2,28,29,32,33)	BRKDUUZCHIMSCW-UHFFFAOYSA-N	50127685	CHEMBL3629150	MAP kinase-activated protein kinase 2	Homo sapiens		 36000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127685&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194068	321902619		CHEMBL3629150					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429643	CCCc1cnc(N)c(CN\C(Nc2ccc(cc2)N(C(=O)c2ccccc2)c2ccccc2)=N/C#N)n1	InChI=1S/C29H28N8O/c1-2-9-23-18-32-27(31)26(35-23)19-33-29(34-20-30)36-22-14-16-25(17-15-22)37(24-12-7-4-8-13-24)28(38)21-10-5-3-6-11-21/h3-8,10-18H,2,9,19H2,1H3,(H2,31,32)(H2,33,34,36)	GTKZWAFUWVQNCJ-UHFFFAOYSA-N	50127686	CHEMBL3629148	MAP kinase-activated protein kinase 2	Homo sapiens		 6900							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127686&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194066	321902620		CHEMBL3629148					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429644	CCCc1cnc(N)c(CN\C(Nc2ccc3[nH]c(=O)oc3c2)=N/C#N)n1	InChI=1S/C17H18N8O2/c1-2-3-11-7-20-15(19)13(23-11)8-21-16(22-9-18)24-10-4-5-12-14(6-10)27-17(26)25-12/h4-7H,2-3,8H2,1H3,(H2,19,20)(H,25,26)(H2,21,22,24)	QSSWEWIMNPALFZ-UHFFFAOYSA-N	50127688	CHEMBL3629147	MAP kinase-activated protein kinase 2	Homo sapiens		 1700							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127688&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194065	321902621		CHEMBL3629147					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429645	CC(C)(C)OC(=O)Nc1ccc(N\C(NCc2nc(cnc2N)C2CC2)=N\C#N)cc1	InChI=1S/C21H26N8O2/c1-21(2,3)31-20(30)28-15-8-6-14(7-9-15)27-19(26-12-22)25-11-17-18(23)24-10-16(29-17)13-4-5-13/h6-10,13H,4-5,11H2,1-3H3,(H2,23,24)(H,28,30)(H2,25,26,27)	WIBNZLWPVAVXKF-UHFFFAOYSA-N	50127689	CHEMBL3629146	MAP kinase-activated protein kinase 2	Homo sapiens		 3300							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127689&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194064	321902622		CHEMBL3629146					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429646	Cc1cnc(N)c(CN\C(Nc2ccc(NC(=O)OC(C)(C)C)cc2)=N/C#N)n1	InChI=1S/C19H24N8O2/c1-12-9-22-16(21)15(25-12)10-23-17(24-11-20)26-13-5-7-14(8-6-13)27-18(28)29-19(2,3)4/h5-9H,10H2,1-4H3,(H2,21,22)(H,27,28)(H2,23,24,26)	AXSDPQNHGXRWSS-UHFFFAOYSA-N	50127691	CHEMBL3629145	MAP kinase-activated protein kinase 2	Homo sapiens		 31000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127691&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194063	321902623		CHEMBL3629145					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429647	CC(C)(C)OC(=O)Nc1ccc(N\C(NCc2nc(Cl)cnc2N)=N\C#N)cc1	InChI=1S/C18H21ClN8O2/c1-18(2,3)29-17(28)26-12-6-4-11(5-7-12)25-16(24-10-20)23-8-13-15(21)22-9-14(19)27-13/h4-7,9H,8H2,1-3H3,(H2,21,22)(H,26,28)(H2,23,24,25)	KOYCAXGCKHRQDL-UHFFFAOYSA-N	50127692	CHEMBL3628993	MAP kinase-activated protein kinase 2	Homo sapiens		 27000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127692&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122193927	321902624		CHEMBL3628993					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429648	Nc1ncc(Cl)nc1CN\C(Nc1ccccc1)=N/C#N	InChI=1S/C13H12ClN7/c14-11-7-17-12(16)10(21-11)6-18-13(19-8-15)20-9-4-2-1-3-5-9/h1-5,7H,6H2,(H2,16,17)(H2,18,19,20)	RTEBIVSOCWILBW-UHFFFAOYSA-N	50127693	CHEMBL3628992	MAP kinase-activated protein kinase 2	Homo sapiens		 26000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127693&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122193926	104019536		CHEMBL3628992				ZINC13489775	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429649	CO\N=C(/NCc1nc(Cl)cnc1N)Nc1ccc(cc1)N(C(=O)c1ccccc1)c1ccccc1	InChI=1S/C26H24ClN7O2/c1-36-33-26(30-16-22-24(28)29-17-23(27)32-22)31-19-12-14-21(15-13-19)34(20-10-6-3-7-11-20)25(35)18-8-4-2-5-9-18/h2-15,17H,16H2,1H3,(H2,28,29)(H2,30,31,33)	WARRIGNVGDVHIN-UHFFFAOYSA-N	50127694	CHEMBL3628991	MAP kinase-activated protein kinase 2	Homo sapiens		 3600							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127694&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122193925	104019537		CHEMBL3628991				ZINC01691583	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429650	CO\N=C(/NCc1nc(Cl)cnc1N)Nc1ccc(NC(=O)OC(C)(C)C)cc1	InChI=1S/C18H24ClN7O3/c1-18(2,3)29-17(27)24-12-7-5-11(6-8-12)23-16(26-28-4)22-9-13-15(20)21-10-14(19)25-13/h5-8,10H,9H2,1-4H3,(H2,20,21)(H,24,27)(H2,22,23,26)	FESLGTJKXVKQJN-UHFFFAOYSA-N	50127695	CHEMBL3628990	MAP kinase-activated protein kinase 2	Homo sapiens		 4200							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127695&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122193924	104019538		CHEMBL3628990				ZINC00388334	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429651	CC(C)(C)OC(=O)Nc1ccc(N\C(NCc2nc(cnc2N)C2CC2)=N\S(C)(=O)=O)cc1	InChI=1S/C21H29N7O4S/c1-21(2,3)32-20(29)26-15-9-7-14(8-10-15)25-19(28-33(4,30)31)24-12-17-18(22)23-11-16(27-17)13-5-6-13/h7-11,13H,5-6,12H2,1-4H3,(H2,22,23)(H,26,29)(H2,24,25,28)	ADFZEDXBJYDMPS-UHFFFAOYSA-N	50127696	CHEMBL3629157	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127696&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194075	104019539		CHEMBL3629157				ZINC00157017	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429652	CCCc1cnc(N)c(CN\C(Nc2ccc(cc2)N(C(=O)c2ccccc2)c2ccccc2)=N/C(=O)c2ccc(Cl)cc2)n1	InChI=1S/C35H32ClN7O2/c1-2-9-28-22-38-32(37)31(40-28)23-39-35(42-33(44)24-14-16-26(36)17-15-24)41-27-18-20-30(21-19-27)43(29-12-7-4-8-13-29)34(45)25-10-5-3-6-11-25/h3-8,10-22H,2,9,23H2,1H3,(H2,37,38)(H2,39,41,42,44)	GOCHRDPQCUPVEC-UHFFFAOYSA-N	50127698	CHEMBL3629156	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127698&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194074	104019541		CHEMBL3629156				ZINC13489765	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50429653	CC(=O)\N=C(/NCc1nc(Cl)cnc1N)Nc1ccc(NC(=O)OC(C)(C)C)cc1	InChI=1S/C19H24ClN7O3/c1-11(28)24-17(23-9-14-16(21)22-10-15(20)27-14)25-12-5-7-13(8-6-12)26-18(29)30-19(2,3)4/h5-8,10H,9H2,1-4H3,(H2,21,22)(H,26,29)(H2,23,24,25,28)	KKECJRBZFARAMT-UHFFFAOYSA-N	50127699	CHEMBL3629149	MAP kinase-activated protein kinase 2	Homo sapiens		>40000							ChEMBL	10.1016/j.bmcl.2015.09.016	10.7270/Q28C9Z2S	26403928			Lin, S; Malkani, S; Lombardo, M; Yang, L; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Hale, JJ	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50127699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50127699&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			122194067	104019542		CHEMBL3629149				ZINC13489770	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50434146	CCN1CCN(CC\C=C\c2ccc3c(Nc4ccc(Sc5nccn5C)c(Cl)c4)c(cnc3c2)C#N)CC1	InChI=1S/C30H32ClN7S/c1-3-37-14-16-38(17-15-37)12-5-4-6-22-7-9-25-27(18-22)34-21-23(20-32)29(25)35-24-8-10-28(26(31)19-24)39-30-33-11-13-36(30)2/h4,6-11,13,18-19,21H,3,5,12,14-17H2,1-2H3,(H,34,35)/b6-4+	OYAMULIHRWEUAR-GQCTYLIASA-N	50274385	4-({3-Chloro-4-[(1-methyl-1H-imidazol-2-yl)thio]phenyl}-amino)-7-[(1E)-4-(4-ethylpiperazin-1-yl)but-1-enyl]quinoline-3-carbonitrile::CHEMBL489058	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2008.09.009	10.7270/Q2DJ5FGD	18815050			Berger, DM; Dutia, M; Powell, D; Floyd, MB; Torres, N; Mallon, R; Wojciechowicz, D; Kim, S; Feldberg, L; Collins, K; Chaudhary, I	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50274385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50274385&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25211064	104118179		CHEMBL489058				ZINC49877677	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50446120	COc1ccc(CN(C)C)c(c1)-c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N	InChI=1S/C27H25N5OS/c1-16-20-9-10-29-24(20)8-7-23(16)31-26-18(13-28)14-30-27-22(26)12-25(34-27)21-11-19(33-4)6-5-17(21)15-32(2)3/h5-12,14,29H,15H2,1-4H3,(H,30,31)	ZZARJEJPLRJJQO-UHFFFAOYSA-N	50255367	2-(2-((dimethylamino)methyl)-5-methoxyphenyl)-4-(4-methyl-1H-indol-5-ylamino)thieno[2,3-b]pyridine-5-carbonitrile::CHEMBL479835	MAP kinase-activated protein kinase 2	Homo sapiens		>5000							ChEMBL	10.1016/j.bmcl.2008.12.021	10.7270/Q2KW5FX7	19111463			Wu, B; Boschelli, DH; Lee, J; Yang, X; Chaudhary, D	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50255367	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50255367&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44570884	104107322		CHEMBL479835				ZINC40414253	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50447586	Cn1c2nc(Nc3ccc4[nH]ccc4c3)ncc2cc(c1=O)S(=O)(=O)c1ccc(F)cc1F	InChI=1S/C22H15F2N5O3S/c1-29-20-13(9-19(21(29)30)33(31,32)18-5-2-14(23)10-16(18)24)11-26-22(28-20)27-15-3-4-17-12(8-15)6-7-25-17/h2-11,25H,1H3,(H,26,27,28)	ZEHBZHZMQSHZFI-UHFFFAOYSA-N	50135286	CHEMBL3745885	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2015.11.045	10.7270/Q24Q7WT8	26762835			Reddy, MV; Akula, B; Jatiani, S; Vasquez-Del Carpio, R; Billa, VK; Mallireddigari, MR; Cosenza, SC; Venkata Subbaiah, DR; Bharathi, EV; Pallela, VR; Ramkumar, P; Jain, R; Aggarwal, AK; Reddy, EP	Icahn School of Medicine at Mount Sinai	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50135286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50135286&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			67240318	336951802		CHEMBL3745885					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50455516	Oc1cc(CNC=C2C(=O)NC(=O)c3ccc(I)cc23)ccc1-c1ccoc1	InChI=1S/C21H15IN2O4/c22-14-2-4-16-17(8-14)18(21(27)24-20(16)26)10-23-9-12-1-3-15(19(25)7-12)13-5-6-28-11-13/h1-8,10-11,23,25H,9H2,(H,24,26,27)	CUISPPCDYZFGCY-UHFFFAOYSA-N	50267255	4-[(4-Furan-3-yl-3-hydroxy-benzylamino)-methylene]-6-iodo-4Hisoquinoline-1,3-dione::CHEMBL504547	MAP kinase-activated protein kinase 2	Homo sapiens		 19000							ChEMBL	10.1021/jm801026e	10.7270/Q27H1JG7	19317452			Tsou, HR; Liu, X; Birnberg, G; Kaplan, J; Otteng, M; Tran, T; Kutterer, K; Tang, Z; Suayan, R; Zask, A; Ravi, M; Bretz, A; Grillo, M; McGinnis, JP; Rabindran, SK; Ayral-Kaloustian, S; Mansour, TS	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50267255	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50267255&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42625986	104114157		CHEMBL504547				ZINC40981103	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50453733	NC[C@H](Cc1cccc(F)c1)NC(=O)c1cc(Br)c(s1)-c1ccnc2[nH]ccc12	InChI=1S/C21H18BrFN4OS/c22-17-10-18(29-19(17)15-4-6-25-20-16(15)5-7-26-20)21(28)27-14(11-24)9-12-2-1-3-13(23)8-12/h1-8,10,14H,9,11,24H2,(H,25,26)(H,27,28)/t14-/m0/s1	KEBMSGAJMPWLNS-AWEZNQCLSA-N	50278836	CHEMBL523586::N-((S)-1-amino-3-(3-fluorophenyl)propan-2-yl)-4-bromo-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2009.02.094	10.7270/Q24X57PX	19285393			Seefeld, MA; Rouse, MB; McNulty, KC; Sun, L; Wang, J; Yamashita, DS; Luengo, JI; Zhang, S; Minthorn, EA; Concha, NO; Heerding, DA	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50278836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50278836&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44592504	104120975		CHEMBL523586				ZINC40429080	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458202	C[C@@H](Nc1c(Nc2cccnc2)c(=O)c1=O)c1ccccc1	InChI=1S/C17H15N3O2/c1-11(12-6-3-2-4-7-12)19-14-15(17(22)16(14)21)20-13-8-5-9-18-10-13/h2-11,19-20H,1H3/t11-/m1/s1	IEAWZSGFVGPNOH-LLVKDONJSA-N	50259567	(R)-3-(1-phenylethylamino)-4-(pyridin-3-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL505335	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259567&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575025	104109830		CHEMBL505335				ZINC49563699	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458203	C[C@@H](Nc1c(Nc2ccncn2)c(=O)c1=O)c1ccccc1	InChI=1S/C16H14N4O2/c1-10(11-5-3-2-4-6-11)19-13-14(16(22)15(13)21)20-12-7-8-17-9-18-12/h2-10,19H,1H3,(H,17,18,20)/t10-/m1/s1	OLCPSDXSIOYXHG-SNVBAGLBSA-N	50259568	3-{[(1R)-1-Phenylethyl]amino}-4-(pyrimidin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL512454	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259568&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25207350	104109831		CHEMBL512454				ZINC40877254	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458204	C[C@@H](Nc1c(Nc2ccn[nH]2)c(=O)c1=O)c1ccccc1	InChI=1S/C15H14N4O2/c1-9(10-5-3-2-4-6-10)17-12-13(15(21)14(12)20)18-11-7-8-16-19-11/h2-9,17H,1H3,(H2,16,18,19)/t9-/m1/s1	MTSGTWVVCJFRLJ-SECBINFHSA-N	50259598	3-{[(1R)-1-Phenylethyl]amino}-4-(1H-pyrazol-3-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL524472	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259598	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259598&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25207352	104109847		CHEMBL524472				ZINC49576957	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458205	C[C@@H](Nc1c(Nc2ccnc(Cl)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C17H14ClN3O2/c1-10(11-5-3-2-4-6-11)20-14-15(17(23)16(14)22)21-12-7-8-19-13(18)9-12/h2-10,20H,1H3,(H,19,21)/t10-/m1/s1	NWOJEWCSLUDKPM-SNVBAGLBSA-N	50259599	3-[(2-Chloropyridin-4-yl)amino]-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL468321	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259599	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259599&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25207353	104109848		CHEMBL468321				ZINC40876829	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458206	C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccccc2)c(=O)c1=O)c1ccccc1	InChI=1S/C23H19N3O2/c1-15(16-8-4-2-5-9-16)25-20-21(23(28)22(20)27)26-18-12-13-24-19(14-18)17-10-6-3-7-11-17/h2-15,25H,1H3,(H,24,26)/t15-/m1/s1	KDSILWKEQMVTNF-OAHLLOKOSA-N	50259600	3-{[(1R)-1-Phenylethyl]amino}-4-[(2-phenylpyridin-4-yl)amino]cyclobut-3-ene-1,2-dione::CHEMBL511419	MAP kinase-activated protein kinase 2	Homo sapiens		 2600							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259600	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259600&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575072	104109849		CHEMBL511419				ZINC49567176	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458207	C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccccc2F)c(=O)c1=O)c1ccccc1	InChI=1S/C23H18FN3O2/c1-14(15-7-3-2-4-8-15)26-20-21(23(29)22(20)28)27-16-11-12-25-19(13-16)17-9-5-6-10-18(17)24/h2-14,26H,1H3,(H,25,27)/t14-/m1/s1	QORWVTRTDZBDNT-CQSZACIVSA-N	50259601	3-{[2-(2-Fluorophenyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL468125	MAP kinase-activated protein kinase 2	Homo sapiens		 5800							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259601	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259601&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575073	104109850		CHEMBL468125				ZINC49538634	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458208	C[C@@H](Nc1c(Nc2ccnc(c2)-c2cccc(F)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C23H18FN3O2/c1-14(15-6-3-2-4-7-15)26-20-21(23(29)22(20)28)27-18-10-11-25-19(13-18)16-8-5-9-17(24)12-16/h2-14,26H,1H3,(H,25,27)/t14-/m1/s1	KFGIOHZBOIRNRH-CQSZACIVSA-N	50259602	3-{[2-(3-Fluorophenyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL449692	MAP kinase-activated protein kinase 2	Homo sapiens		 6600							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259602	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259602&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575074	104109851		CHEMBL449692				ZINC49841165	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458209	COc1cccc(c1)-c1cc(Nc2c(N[C@H](C)c3ccccc3)c(=O)c2=O)ccn1	InChI=1S/C24H21N3O3/c1-15(16-7-4-3-5-8-16)26-21-22(24(29)23(21)28)27-18-11-12-25-20(14-18)17-9-6-10-19(13-17)30-2/h3-15,26H,1-2H3,(H,25,27)/t15-/m1/s1	NQDNWDAHTHBILR-OAHLLOKOSA-N	50259635	3-{[2-(3-Methoxyphenyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL479290	MAP kinase-activated protein kinase 2	Homo sapiens		 3700							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575124	104109866		CHEMBL479290				ZINC49552081	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458210	C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C22H18N4O2/c1-14(15-5-3-2-4-6-15)25-19-20(22(28)21(19)27)26-17-9-12-24-18(13-17)16-7-10-23-11-8-16/h2-14,25H,1H3,(H,24,26)/t14-/m1/s1	NXGZIQMPMGIFQK-CQSZACIVSA-N	50259636	3-(2,40-Bipyridin-4-ylamino)-4-{[(1R)-1-phenylethyl]-amino}-cyclobut-3-ene-1,2-dione::CHEMBL469490	MAP kinase-activated protein kinase 2	Homo sapiens		 3600							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259636&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575125	104109867		CHEMBL469490				ZINC49538653	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458211	C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccco2)c(=O)c1=O)c1ccccc1	InChI=1S/C21H17N3O3/c1-13(14-6-3-2-4-7-14)23-18-19(21(26)20(18)25)24-15-9-10-22-16(12-15)17-8-5-11-27-17/h2-13,23H,1H3,(H,22,24)/t13-/m1/s1	WSGJNLVHAHAWQS-CYBMUJFWSA-N	50259637	3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL519113	MAP kinase-activated protein kinase 2	Homo sapiens		 5300							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259637&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575126	104109868		CHEMBL519113				ZINC49573652	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458212	C[C@@H](Nc1c(Nc2ccnc(c2)-c2ccsc2)c(=O)c1=O)c1ccccc1	InChI=1S/C21H17N3O2S/c1-13(14-5-3-2-4-6-14)23-18-19(21(26)20(18)25)24-16-7-9-22-17(11-16)15-8-10-27-12-15/h2-13,23H,1H3,(H,22,24)/t13-/m1/s1	IHKOUBVQGUHCQJ-CYBMUJFWSA-N	50259638	3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL481248	MAP kinase-activated protein kinase 2	Homo sapiens		 5400							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259638&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575127	104109869		CHEMBL481248				ZINC40412531	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458213	C[C@@H](Nc1c(Nc2ccnc(Nc3ccccc3)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C23H20N4O2/c1-15(16-8-4-2-5-9-16)25-20-21(23(29)22(20)28)27-18-12-13-24-19(14-18)26-17-10-6-3-7-11-17/h2-15,25H,1H3,(H2,24,26,27)/t15-/m1/s1	YWUUUUILIRAHAZ-OAHLLOKOSA-N	50259639	3-[(2-Anilinopyridin-4-yl)amino]-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL481249	MAP kinase-activated protein kinase 2	Homo sapiens		 9100							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259639&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575128	104109870		CHEMBL481249				ZINC40934566	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458214	C[C@@H](Nc1c(Nc2ccnc(Nc3cccc(c3)C(N)=O)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C24H21N5O3/c1-14(15-6-3-2-4-7-15)27-20-21(23(31)22(20)30)29-18-10-11-26-19(13-18)28-17-9-5-8-16(12-17)24(25)32/h2-14,27H,1H3,(H2,25,32)(H2,26,28,29)/t14-/m1/s1	MIBQVKWORSUIKS-CQSZACIVSA-N	50258906	3-({4-[(3,4-Dioxo-2-{[(1R)-1-phenylethyl]amino}-cyclobut-1-en-1-yl)amino]pyridin-2-yl}amino)benzamide::CHEMBL513870	MAP kinase-activated protein kinase 2	Homo sapiens		 2400							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258906	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258906&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574421	104109467		CHEMBL513870				ZINC49567441	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458215	C[C@@H](Nc1c(Nc2ccnc(Nc3ccncn3)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C21H18N6O2/c1-13(14-5-3-2-4-6-14)25-18-19(21(29)20(18)28)26-15-7-10-23-17(11-15)27-16-8-9-22-12-24-16/h2-13,25H,1H3,(H2,22,23,24,26,27)/t13-/m1/s1	QIARVAMRJALGOD-CYBMUJFWSA-N	50258907	3-{[(1R)-1-Phenylethyl]amino}-4-{[2-(pyrimidin-4-ylamino)pyridin-4-yl]amino}cyclobut-3-ene-1,2-dione::CHEMBL469124	MAP kinase-activated protein kinase 2	Homo sapiens		 670							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258907	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258907&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574422	104109468		CHEMBL469124				ZINC40394286	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458216	C[C@@H](Nc1c(Nc2ccnc(Nc3cnccn3)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C21H18N6O2/c1-13(14-5-3-2-4-6-14)25-18-19(21(29)20(18)28)26-15-7-8-23-16(11-15)27-17-12-22-9-10-24-17/h2-13,25H,1H3,(H2,23,24,26,27)/t13-/m1/s1	UINFNCTZTORHRM-CYBMUJFWSA-N	50258908	3-{[(1R)-1-Phenylethyl]amino}-4-{[2-(pyrazin-2-ylamino)pyridin-4-yl]amino}cyclobut-3-ene-1,2-dione::CHEMBL525927	MAP kinase-activated protein kinase 2	Homo sapiens		 1600							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258908	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258908&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574423	104109469		CHEMBL525927				ZINC49917639	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458217	C[C@@H](Nc1c(Nc2ccnc(Nc3ncccn3)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C21H18N6O2/c1-13(14-6-3-2-4-7-14)25-17-18(20(29)19(17)28)26-15-8-11-22-16(12-15)27-21-23-9-5-10-24-21/h2-13,25H,1H3,(H2,22,23,24,26,27)/t13-/m1/s1	QBJIOCUFCVQFQI-CYBMUJFWSA-N	50258909	3-{[(1R)-1-Phenylethyl]amino}-4-{[2-(pyrimidin-2-ylamino)pyridin-4-yl]amino}cyclobut-3-ene-1,2-dione::CHEMBL466009	MAP kinase-activated protein kinase 2	Homo sapiens		 2300							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258909&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574424	104109470		CHEMBL466009				ZINC49538491	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458218	C[C@@H](Nc1c(Nc2ccnc(NC(C)=O)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C19H18N4O3/c1-11(13-6-4-3-5-7-13)21-16-17(19(26)18(16)25)23-14-8-9-20-15(10-14)22-12(2)24/h3-11,21H,1-2H3,(H2,20,22,23,24)/t11-/m1/s1	YEUZJEJCUQVIFH-LLVKDONJSA-N	50258910	CHEMBL468292::N-{4-[(3,4-Dioxo-2-{[(1R)-1-phenylethyl]amino}-cyclobut-1-en-1-yl)amino]pyridin-2-yl}acetamidedione	MAP kinase-activated protein kinase 2	Homo sapiens		 3800							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258910&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574425	104109471		CHEMBL468292				ZINC49538642	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458219	C[C@@H](Nc1c(Nc2ccnc(NC(=O)c3cccnc3)c2)c(=O)c1=O)c1ccccc1	InChI=1S/C23H19N5O3/c1-14(15-6-3-2-4-7-15)26-19-20(22(30)21(19)29)27-17-9-11-25-18(12-17)28-23(31)16-8-5-10-24-13-16/h2-14,26H,1H3,(H2,25,27,28,31)/t14-/m1/s1	MAIPYHWPCVNDJP-CQSZACIVSA-N	50258950	CHEMBL468322::N-{4-[(3,4-Dioxo-2-{[(1R)-1-phenylethyl]amino}-cyclobut-1-en-1-yl)amino]pyridin-2-yl}nicotinamide	MAP kinase-activated protein kinase 2	Homo sapiens		 1300							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258950	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258950&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574469	104109476		CHEMBL468322				ZINC49538633	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458230	C[C@@H](Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C17H15N3O2/c1-11(12-5-3-2-4-6-12)19-14-15(17(22)16(14)21)20-13-7-9-18-10-8-13/h2-11,19H,1H3,(H,18,20)/t11-/m1/s1	MCBPNFWHHNJTGN-LLVKDONJSA-N	50259376	3-((R)-1-Phenyl-ethylamino)-4-(pyridin-4-ylamino)-cyclobut-3-ene-1,2-dione::3-{[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL466496	MAP kinase-activated protein kinase 2	Homo sapiens		 8900							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259376	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259376&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	793	3FPM	15295578	104109674		CHEMBL466496	DB07234			ZINC49538482	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458231	C[C@H](Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C17H15N3O2/c1-11(12-5-3-2-4-6-12)19-14-15(17(22)16(14)21)20-13-7-9-18-10-8-13/h2-11,19H,1H3,(H,18,20)/t11-/m0/s1	MCBPNFWHHNJTGN-NSHDSACASA-N	50259377	3-{[(1S)-1-Phenylethyl]amino}-4-(pyridin-4-ylamino)-cyclobut-3-ene-1,2-dione::CHEMBL512784	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259377	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259377&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574873	104109675		CHEMBL512784				ZINC49567225	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458232	O=c1c(NCc2ccccc2)c(Nc2ccncc2)c1=O	InChI=1S/C16H13N3O2/c20-15-13(18-10-11-4-2-1-3-5-11)14(16(15)21)19-12-6-8-17-9-7-12/h1-9,18H,10H2,(H,17,19)	YFNYENFUDVWQQF-UHFFFAOYSA-N	50259378	3-(Benzylamino)-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL466700	MAP kinase-activated protein kinase 2	Homo sapiens		 88000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259378&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25205757	104109676		CHEMBL466700				ZINC40876555	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458233	CC(C)(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C18H17N3O2/c1-18(2,12-6-4-3-5-7-12)21-15-14(16(22)17(15)23)20-13-8-10-19-11-9-13/h3-11,21H,1-2H3,(H,19,20)	PISFELLVHSVOPU-UHFFFAOYSA-N	50259379	3-[(1-Methyl-1-phenylethyl)amino]-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL504830	MAP kinase-activated protein kinase 2	Homo sapiens		 2300							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259379&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25207519	104109677		CHEMBL504830				ZINC49563600	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458234	C[C@@H](Nc1c(Nc2ccncc2)c(=O)c1=O)C1CCCCC1	InChI=1S/C17H21N3O2/c1-11(12-5-3-2-4-6-12)19-14-15(17(22)16(14)21)20-13-7-9-18-10-8-13/h7-12,19H,2-6H2,1H3,(H,18,20)/t11-/m1/s1	KBRJIBFRLFVYJL-LLVKDONJSA-N	50259380	3-{[(1R)-1-Cyclohexylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL466701	MAP kinase-activated protein kinase 2	Homo sapiens		 65000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259380&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25207355	104109678		CHEMBL466701				ZINC49538481	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458235	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1nccs1	InChI=1S/C14H12N4O2S/c1-8(14-16-6-7-21-14)17-10-11(13(20)12(10)19)18-9-2-4-15-5-3-9/h2-8,17H,1H3,(H,15,18)	VEEIJXOIIPWFLM-UHFFFAOYSA-N	50259478	3-(Pyridin-4-ylamino)-4-{[1-(1,3-thiazol-2-yl)ethyl]-amino}cyclobut-3-ene-1,2-dione::CHEMBL467729	MAP kinase-activated protein kinase 2	Homo sapiens		 81000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259478&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574928	104109759		CHEMBL467729				ZINC49538647	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458236	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1F	InChI=1S/C17H14FN3O2/c1-10(12-4-2-3-5-13(12)18)20-14-15(17(23)16(14)22)21-11-6-8-19-9-7-11/h2-10,20H,1H3,(H,19,21)	UXUWXYVYMSXPBA-UHFFFAOYSA-N	50259479	3-{[1-(2-Fluorophenyl)ethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL467730	MAP kinase-activated protein kinase 2	Homo sapiens		 9300							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259479&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574929	104109760		CHEMBL467730				ZINC49768101	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458237	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1O	InChI=1S/C17H15N3O3/c1-10(12-4-2-3-5-13(12)21)19-14-15(17(23)16(14)22)20-11-6-8-18-9-7-11/h2-10,19,21H,1H3,(H,18,20)	QFVMABQAPDBPMA-UHFFFAOYSA-N	50259480	3-{[1-(2-Hydroxyphenyl)ethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL513154	MAP kinase-activated protein kinase 2	Homo sapiens		 33000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574930	104109761		CHEMBL513154				ZINC49567328	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458238	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1cccc(C)c1	InChI=1S/C18H17N3O2/c1-11-4-3-5-13(10-11)12(2)20-15-16(18(23)17(15)22)21-14-6-8-19-9-7-14/h3-10,12,20H,1-2H3,(H,19,21)	TURNIBWUQGWPMB-UHFFFAOYSA-N	50259481	3-{[1-(3-Methylphenyl)ethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL467731	MAP kinase-activated protein kinase 2	Homo sapiens		 49000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259481&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574931	104109762		CHEMBL467731				ZINC49538649	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458239	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1cccc(N)c1	InChI=1S/C17H16N4O2/c1-10(11-3-2-4-12(18)9-11)20-14-15(17(23)16(14)22)21-13-5-7-19-8-6-13/h2-10,20H,18H2,1H3,(H,19,21)	QAQZEGFCIMHNPC-UHFFFAOYSA-N	50259482	3-{[1-(3-Aminophenyl)ethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL467732	MAP kinase-activated protein kinase 2	Homo sapiens		 14000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259482&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574932	104109763		CHEMBL467732				ZINC49538650	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458240	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1cccc(O)c1	InChI=1S/C17H15N3O3/c1-10(11-3-2-4-13(21)9-11)19-14-15(17(23)16(14)22)20-12-5-7-18-8-6-12/h2-10,19,21H,1H3,(H,18,20)	CYMBWEFLCHYQDR-UHFFFAOYSA-N	50259483	3-{[1-(3-Hydroxyphenyl)ethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL467532	MAP kinase-activated protein kinase 2	Homo sapiens		 380							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259483&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574933	104109764		CHEMBL467532				ZINC49538487	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458241	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1cccc(NC(C)=O)c1	InChI=1S/C19H18N4O3/c1-11(13-4-3-5-15(10-13)22-12(2)24)21-16-17(19(26)18(16)25)23-14-6-8-20-9-7-14/h3-11,21H,1-2H3,(H,20,23)(H,22,24)	XYZXHSASVDSJGS-UHFFFAOYSA-N	50259528	CHEMBL452699::N-[3-(1-{[3,4-Dioxo-2-(pyridin-4-ylamino)cyclobut-1-en-1-yl]amino}ethyl)phenyl]acetamide	MAP kinase-activated protein kinase 2	Homo sapiens		 5500							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259528&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574982	104109799		CHEMBL452699				ZINC40835613	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458242	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1cccc(NS(C)(=O)=O)c1	InChI=1S/C18H18N4O4S/c1-11(12-4-3-5-14(10-12)22-27(2,25)26)20-15-16(18(24)17(15)23)21-13-6-8-19-9-7-13/h3-11,20,22H,1-2H3,(H,19,21)	XIZCVYOKGCPBNX-UHFFFAOYSA-N	50259529	CHEMBL511219::N-[3-(1-{[3,4-Dioxo-2-(pyridin-4-ylamino)cyclobut-1-en-1-yl]amino}ethyl)phenyl]methanesulfonamide	MAP kinase-activated protein kinase 2	Homo sapiens		 24000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259529&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44574983	104109800		CHEMBL511219				ZINC49567173	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458243	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccc(F)cc1	InChI=1S/C17H14FN3O2/c1-10(11-2-4-12(18)5-3-11)20-14-15(17(23)16(14)22)21-13-6-8-19-9-7-13/h2-10,20H,1H3,(H,19,21)	VQWUXYUJLOWNIP-UHFFFAOYSA-N	50259530	3-{[1-(4-Fluorophenyl)ethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL467078	MAP kinase-activated protein kinase 2	Homo sapiens		 8200							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259530&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25205591	104109801		CHEMBL467078				ZINC49538470	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458244	CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccc(O)cc1	InChI=1S/C17H15N3O3/c1-10(11-2-4-13(21)5-3-11)19-14-15(17(23)16(14)22)20-12-6-8-18-9-7-12/h2-10,19,21H,1H3,(H,18,20)	RMWUQCYBKQXWFK-UHFFFAOYSA-N	50259531	3-{[1-(4-hydroxyphenyl)ethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL512791	MAP kinase-activated protein kinase 2	Homo sapiens		 5000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259531&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25206391	104109802		CHEMBL512791				ZINC49567254	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458245	NC(=O)C(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C17H14N4O3/c18-17(24)12(10-4-2-1-3-5-10)21-14-13(15(22)16(14)23)20-11-6-8-19-9-7-11/h1-9,12,21H,(H2,18,24)(H,19,20)	SOUYYRXENUITFU-UHFFFAOYSA-N	50259532	2-{[3,4-Dioxo-2-(pyridin-4-ylamino)cyclobut-1-en-1-yl]amino}-2-phenylacetamide::CHEMBL467079	MAP kinase-activated protein kinase 2	Homo sapiens		 4500							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259532&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25206064	104109803		CHEMBL467079				ZINC49538472	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458246	NC(=O)C(Nc1c(Nc2ccncc2)c(=O)c1=O)c1cccc(O)c1	InChI=1S/C17H14N4O4/c18-17(25)12(9-2-1-3-11(22)8-9)21-14-13(15(23)16(14)24)20-10-4-6-19-7-5-10/h1-8,12,21-22H,(H2,18,25)(H,19,20)	GPXKVULNYYNGDP-UHFFFAOYSA-N	50259563	2-{[3,4-Dioxo-2-(pyridin-4-ylamino)cyclobut-1-en-1-yl]amino}-2-(3-hydroxyphenyl)acetamide::CHEMBL511410	MAP kinase-activated protein kinase 2	Homo sapiens		 390							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259563&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25207521	104109826		CHEMBL511410				ZINC49567144	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458247	OCC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C17H15N3O3/c21-10-13(11-4-2-1-3-5-11)20-15-14(16(22)17(15)23)19-12-6-8-18-9-7-12/h1-9,13,20-21H,10H2,(H,18,19)	DAGJEDQAVYEPNE-UHFFFAOYSA-N	50259564	3-{[(1S)-2-Hydroxy-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL467911	MAP kinase-activated protein kinase 2	Homo sapiens		 5300							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259564&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44575024	104109827		CHEMBL467911				ZINC49538495	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458248	C[C@@H](N(C)c1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C18H17N3O2/c1-12(13-6-4-3-5-7-13)21(2)16-15(17(22)18(16)23)20-14-8-10-19-11-9-14/h3-12H,1-2H3,(H,19,20)/t12-/m1/s1	MGQAPAVFPDBGHB-GFCCVEGCSA-N	50259565	3-{Methyl[(1R)-1-phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione::CHEMBL467912	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259565&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25206065	104109828		CHEMBL467912				ZINC40401864	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50458249	C[C@@H](Nc1c(N(C)c2ccncc2)c(=O)c1=O)c1ccccc1	InChI=1S/C18H17N3O2/c1-12(13-6-4-3-5-7-13)20-15-16(18(23)17(15)22)21(2)14-8-10-19-11-9-14/h3-12,20H,1-2H3/t12-/m1/s1	KXRUGBLLVWDJAY-GFCCVEGCSA-N	50259566	3-[Methyl(pyridin-4-yl)amino]-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione::CHEMBL467913	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmc.2009.03.041	10.7270/Q2WW7HK4	19364658			Lovering, F; Kirincich, S; Wang, W; Combs, K; Resnick, L; Sabalski, JE; Butera, J; Liu, J; Parris, K; Telliez, JB	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50259566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50259566&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25207516	104109829		CHEMBL467913				ZINC49538496	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50460386	CN1CCN(CCOc2ccc(cc2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1	InChI=1S/C28H30N6O/c1-20-24-9-10-31-27(24)8-7-26(20)32-28-22(17-29)18-30-19-25(28)21-3-5-23(6-4-21)35-16-15-34-13-11-33(2)12-14-34/h3-10,18-19,31H,11-16H2,1-2H3,(H,30,32)	LTGPAFCQBMWTBC-UHFFFAOYSA-N	50258822	4-(4-methyl-1H-indol-5-ylamino)-5-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)nicotinonitrile::CHEMBL467069	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2009.04.126	10.7270/Q29W0FD4	19447612			Boschelli, DH; Wang, D; Prashad, AS; Subrath, J; Wu, B; Niu, C; Lee, J; Yang, X; Brennan, A; Chaudhary, D	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50258822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50258822&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24825721	104109416		CHEMBL467069				ZINC40891505	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50456137	O[C@H]1CC[C@@H](CC1)c1[nH]ncc1-c1ccnc(NC2CCCC2)n1	InChI=1S/C18H25N5O/c24-14-7-5-12(6-8-14)17-15(11-20-23-17)16-9-10-19-18(22-16)21-13-3-1-2-4-13/h9-14,24H,1-8H2,(H,20,23)(H,19,21,22)/t12-,14-	JCJAEEODSKNKTC-MQMHXKEQSA-N	50277910	4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyrazol-3-yl)cyclohexanol::CHEMBL507249	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2009.03.023	10.7270/Q26H4H9D	19327989			Humphries, PS; Lafontaine, JA; Agree, CS; Alexander, D; Chen, P; Do, QQ; Li, LY; Lunney, EA; Rajapakse, RJ; Siegel, K; Timofeevski, SL; Wang, T; Wilhite, DM	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50277910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50277910&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44591740	104120373		CHEMBL507249				ZINC40379254	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50486079	Nc1ncnc2n(cc(-c3cccc(OC[C@@H]4CCCO4)c3)c12)[C@@H]1C[C@H](CN2CCC2)C1	InChI=1S/C25H31N5O2/c26-24-23-22(18-4-1-5-20(12-18)32-15-21-6-2-9-31-21)14-30(25(23)28-16-27-24)19-10-17(11-19)13-29-7-3-8-29/h1,4-5,12,14,16-17,19,21H,2-3,6-11,13,15H2,(H2,26,27,28)/t17-,19+,21-/m0/s1	UYHKCQAFCWYUAF-DSKINZAPSA-N	50157881	CHEMBL3787614	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2016.02.075	10.7270/Q29K4D4J	26951753			Fairhurst, RA; Marsilje, TH; Stutz, S; Boos, A; Niklaus, M; Chen, B; Jiang, S; Lu, W; Furet, P; McCarthy, C; Stauffer, F; Guagnano, V; Vaupel, A; Michellys, PY; Schnell, C; Jeay, S	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157881&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			67035556	340134184		CHEMBL3787614					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50486120	Nc1ncnc2n(cc(-c3cccc(OCC45CCC(CC4)O5)c3)c12)[C@@H]1C[C@H](CN2CCC2)C1	InChI=1S/C27H33N5O2/c28-25-24-23(19-3-1-4-22(13-19)33-16-27-7-5-21(34-27)6-8-27)15-32(26(24)30-17-29-25)20-11-18(12-20)14-31-9-2-10-31/h1,3-4,13,15,17-18,20-21H,2,5-12,14,16H2,(H2,28,29,30)/t18-,20+,21?,27?	LYOCYPVMXHFJAK-YFHMBBFDSA-N	50158429	CHEMBL3785500	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2016.02.075	10.7270/Q29K4D4J	26951753			Fairhurst, RA; Marsilje, TH; Stutz, S; Boos, A; Niklaus, M; Chen, B; Jiang, S; Lu, W; Furet, P; McCarthy, C; Stauffer, F; Guagnano, V; Vaupel, A; Michellys, PY; Schnell, C; Jeay, S	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50158429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50158429&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			67035106	340134290		CHEMBL3785500					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50493774	C[C@@H](N1c2cc(ccc2C(=O)NC1(C)C)-n1c2cccnc2[nH]c1=O)c1ccccc1	InChI=1S/C24H23N5O2/c1-15(16-8-5-4-6-9-16)29-20-14-17(11-12-18(20)22(30)27-24(29,2)3)28-19-10-7-13-25-21(19)26-23(28)31/h4-15H,1-3H3,(H,27,30)(H,25,26,31)/t15-/m1/s1	WNYKGJHEQVIFGL-OAHLLOKOSA-N	50166588	CHEMBL3798011	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL	10.1016/j.bmc.2016.04.008	10.7270/Q27W6F29	27117263			Katoh, T; Takai, T; Yukawa, T; Tsukamoto, T; Watanabe, E; Mototani, H; Arita, T; Hayashi, H; Nakagawa, H; Klein, MG; Zou, H; Sang, BC; Snell, G; Nakada, Y	Takeda Pharmaceutical Co., Ltd	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50166588	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50166588&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91933875	341097853		CHEMBL3798011					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50486387	Nc1ncnc2n(cc(-c3cccc(O)c3)c12)[C@@H]1C[C@H](CN2CCC2)C1	InChI=1S/C20H23N5O/c21-19-18-17(14-3-1-4-16(26)9-14)11-25(20(18)23-12-22-19)15-7-13(8-15)10-24-5-2-6-24/h1,3-4,9,11-13,15,26H,2,5-8,10H2,(H2,21,22,23)/t13-,15+	BETBNWGUKZUUAX-OTVXOJSOSA-N	50157880	CHEMBL3787112	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2016.02.075	10.7270/Q29K4D4J	26951753			Fairhurst, RA; Marsilje, TH; Stutz, S; Boos, A; Niklaus, M; Chen, B; Jiang, S; Lu, W; Furet, P; McCarthy, C; Stauffer, F; Guagnano, V; Vaupel, A; Michellys, PY; Schnell, C; Jeay, S	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157880&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			67035086	340134183		CHEMBL3787112					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50486644	Nc1ncnc2n(cc(-c3cccc(OCc4ccccc4)c3)c12)[C@@H]1C[C@H](CN2CCC2)C1	InChI=1S/C27H29N5O/c28-26-25-24(21-8-4-9-23(14-21)33-17-19-6-2-1-3-7-19)16-32(27(25)30-18-29-26)22-12-20(13-22)15-31-10-5-11-31/h1-4,6-9,14,16,18,20,22H,5,10-13,15,17H2,(H2,28,29,30)/t20-,22+	AECDBHGVIIRMOI-GRGXKFILSA-N	50157879	CHEMBL1614712	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2016.02.075	10.7270/Q29K4D4J	26951753			Fairhurst, RA; Marsilje, TH; Stutz, S; Boos, A; Niklaus, M; Chen, B; Jiang, S; Lu, W; Furet, P; McCarthy, C; Stauffer, F; Guagnano, V; Vaupel, A; Michellys, PY; Schnell, C; Jeay, S	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157879&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	66A	5HZN	11476171	340134182		CHEMBL1614712					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50486770	CC(=O)N1CCN(CC1)[C@H]1C[C@H](C1)n1cc(-c2cccc(OC[C@@H]3CCCO3)c2F)c2c(N)ncnc12	InChI=1S/C27H33FN6O3/c1-17(35)32-7-9-33(10-8-32)18-12-19(13-18)34-14-22(24-26(29)30-16-31-27(24)34)21-5-2-6-23(25(21)28)37-15-20-4-3-11-36-20/h2,5-6,14,16,18-20H,3-4,7-13,15H2,1H3,(H2,29,30,31)/t18-,19+,20-/m0/s1	KJDKBIYPTUYYHT-ZCNNSNEGSA-N	50157628	CHEMBL3786167	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2016.02.075	10.7270/Q29K4D4J	26951753			Fairhurst, RA; Marsilje, TH; Stutz, S; Boos, A; Niklaus, M; Chen, B; Jiang, S; Lu, W; Furet, P; McCarthy, C; Stauffer, F; Guagnano, V; Vaupel, A; Michellys, PY; Schnell, C; Jeay, S	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50157628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50157628&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			68293660	340134090		CHEMBL3786167					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50486772	CC(=O)N1CCN(CC1)[C@H]1C[C@H](C1)n1cc(-c2cc(OC[C@@H]3CCCO3)ccc2F)c2c(N)ncnc12	InChI=1S/C27H33FN6O3/c1-17(35)32-6-8-33(9-7-32)18-11-19(12-18)34-14-23(25-26(29)30-16-31-27(25)34)22-13-20(4-5-24(22)28)37-15-21-3-2-10-36-21/h4-5,13-14,16,18-19,21H,2-3,6-12,15H2,1H3,(H2,29,30,31)/t18-,19+,21-/m0/s1	YXLQJZQRBVGUCM-ZVDOUQERSA-N	50156383	CHEMBL3785951	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2016.02.075	10.7270/Q29K4D4J	26951753			Fairhurst, RA; Marsilje, TH; Stutz, S; Boos, A; Niklaus, M; Chen, B; Jiang, S; Lu, W; Furet, P; McCarthy, C; Stauffer, F; Guagnano, V; Vaupel, A; Michellys, PY; Schnell, C; Jeay, S	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50156383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50156383&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			68293638	340133906		CHEMBL3785951					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50496453	CN1CCN(CC1)c1ccc(C(=O)Nc2n[nH]c3ccc(Cc4cc(F)cc(F)c4)cc23)c(NC2CCOCC2)c1	InChI=1S/C31H34F2N6O2/c1-38-8-10-39(11-9-38)25-3-4-26(29(19-25)34-24-6-12-41-13-7-24)31(40)35-30-27-17-20(2-5-28(27)36-37-30)14-21-15-22(32)18-23(33)16-21/h2-5,15-19,24,34H,6-14H2,1H3,(H2,35,36,37,40)	HAYYBYPASCDWEQ-UHFFFAOYSA-N	158154	US10081622, Compound 11::US10370379, Entrectinib::US11059827, Compound Entrectinib::US11267806, Compound T-12::US9029356, 11::US9255087, 11::US9616059, 11	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.6b00064	10.7270/Q27M09TG	27003761			Menichincheri, M; Ardini, E; Magnaghi, P; Avanzi, N; Banfi, P; Bossi, R; Buffa, L; Canevari, G; Ceriani, L; Colombo, M; Corti, L; Donati, D; Fasolini, M; Felder, E; Fiorelli, C; Fiorentini, F; Galvani, A; Isacchi, A; Borgia, AL; Marchionni, C; Nesi, M; Orrenius, C; Panzeri, A; Pesenti, E; Rusconi, L; Saccardo, MB; Vanotti, E; Perrone, E; Orsini, P	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=158154	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=158154&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	YMX	5KVT,5FTO	74394320	254815348							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50497638	CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O	InChI=1S/C98H171N37O26/c1-45(2)41-68(84(150)115-44-72(139)135-73(47(5)6)93(159)124-50(9)76(142)125-57(16)94(160)161)134-91(157)67(33-35-71(102)138)132-90(156)65(27-22-40-114-98(109)110)130-81(147)55(14)123-92(158)69(42-46(3)4)133-82(148)56(15)121-85(151)61(23-17-18-36-99)126-79(145)53(12)120-87(153)63(25-20-38-112-96(105)106)128-80(146)54(13)122-88(154)66(32-34-70(101)137)131-89(155)64(26-21-39-113-97(107)108)129-77(143)51(10)117-74(140)48(7)116-75(141)49(8)119-86(152)62(24-19-37-111-95(103)104)127-78(144)52(11)118-83(149)60(100)43-58-28-30-59(136)31-29-58/h28-31,45-57,60-69,73,136H,17-27,32-44,99-100H2,1-16H3,(H2,101,137)(H2,102,138)(H,115,150)(H,116,141)(H,117,140)(H,118,149)(H,119,152)(H,120,153)(H,121,151)(H,122,154)(H,123,158)(H,124,159)(H,125,142)(H,126,145)(H,127,144)(H,128,146)(H,129,143)(H,130,147)(H,131,155)(H,132,156)(H,133,148)(H,134,157)(H,135,139)(H,160,161)(H4,103,104,111)(H4,105,106,112)(H4,107,108,113)(H4,109,110,114)/t48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,73-/m0/s1	NXUWTKIOMJSLSV-DEEZXRHXSA-N	50172064	CHEMBL3809901	MAP kinase-activated protein kinase 2	Homo sapiens		 22000							ChEMBL	10.1021/acs.jmedchem.5b01457	10.7270/Q2D50PW0	26502061			Fiore, M; Forli, S; Manetti, F	Universit&#163; di Siena	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172064	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172064&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			127043567	104058217		CHEMBL3809901				ZINC28528957	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50497639	CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O	InChI=1S/C99H172N38O27/c1-45(2)40-67(84(152)117-44-73(142)137-74(47(5)6)94(162)125-50(9)77(145)126-56(15)95(163)164)135-91(159)66(32-34-71(103)140)133-90(158)64(26-21-39-116-99(111)112)131-93(161)69(43-72(104)141)136-92(160)68(41-46(3)4)134-82(150)55(14)123-85(153)60(22-16-17-35-100)127-80(148)53(12)122-87(155)62(24-19-37-114-97(107)108)129-81(149)54(13)124-88(156)65(31-33-70(102)139)132-89(157)63(25-20-38-115-98(109)110)130-78(146)51(10)119-75(143)48(7)118-76(144)49(8)121-86(154)61(23-18-36-113-96(105)106)128-79(147)52(11)120-83(151)59(101)42-57-27-29-58(138)30-28-57/h27-30,45-56,59-69,74,138H,16-26,31-44,100-101H2,1-15H3,(H2,102,139)(H2,103,140)(H2,104,141)(H,117,152)(H,118,144)(H,119,143)(H,120,151)(H,121,154)(H,122,155)(H,123,153)(H,124,156)(H,125,162)(H,126,145)(H,127,148)(H,128,147)(H,129,149)(H,130,146)(H,131,161)(H,132,157)(H,133,158)(H,134,150)(H,135,159)(H,136,160)(H,137,142)(H,163,164)(H4,105,106,113)(H4,107,108,114)(H4,109,110,115)(H4,111,112,116)/t48-,49-,50-,51-,52-,53-,54-,55-,56-,59-,60-,61-,62-,63-,64-,65-,66-,67-,68-,69-,74-/m0/s1	MHOAPEXIEMFANF-RJLOIDLMSA-N	50172065	CHEMBL3809381	MAP kinase-activated protein kinase 2	Homo sapiens		 5800							ChEMBL	10.1021/acs.jmedchem.5b01457	10.7270/Q2D50PW0	26502061			Fiore, M; Forli, S; Manetti, F	Universit&#163; di Siena	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172065	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172065&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			127044221	104058218		CHEMBL3809381				ZINC28528130	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50497640	CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](C)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)[C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(O)=O	InChI=1S/C128H218N44O26/c1-19-69(13)100(121(195)162-82(38-25-27-47-129)107(181)152-72(16)103(177)164-91(55-65(5)6)117(191)169-95(60-97(133)174)119(193)160-86(42-31-51-146-126(138)139)111(185)161-89(45-46-96(132)173)112(186)167-90(54-64(3)4)106(180)151-63-98(175)170-99(68(11)12)120(194)154-71(15)102(176)155-74(18)123(197)198)172-114(188)88(44-33-53-148-128(142)143)157-110(184)85(41-30-50-145-125(136)137)159-116(190)93(57-67(9)10)168-118(192)94(59-76-62-150-81-37-24-22-35-78(76)81)165-104(178)73(17)153-108(182)83(39-26-28-48-130)163-122(196)101(70(14)20-2)171-113(187)87(43-32-52-147-127(140)141)156-109(183)84(40-29-49-144-124(134)135)158-115(189)92(56-66(7)8)166-105(179)79(131)58-75-61-149-80-36-23-21-34-77(75)80/h21-24,34-37,61-62,64-74,79,82-95,99-101,149-150H,19-20,25-33,38-60,63,129-131H2,1-18H3,(H2,132,173)(H2,133,174)(H,151,180)(H,152,181)(H,153,182)(H,154,194)(H,155,176)(H,156,183)(H,157,184)(H,158,189)(H,159,190)(H,160,193)(H,161,185)(H,162,195)(H,163,196)(H,164,177)(H,165,178)(H,166,179)(H,167,186)(H,168,192)(H,169,191)(H,170,175)(H,171,187)(H,172,188)(H,197,198)(H4,134,135,144)(H4,136,137,145)(H4,138,139,146)(H4,140,141,147)(H4,142,143,148)/t69-,70-,71-,72-,73-,74-,79-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,99-,100-,101-/m0/s1	IKVGNKZJRMCCFZ-PVAFRFBUSA-N	50172066	CHEMBL3808687	MAP kinase-activated protein kinase 2	Homo sapiens		 740							ChEMBL	10.1021/acs.jmedchem.5b01457	10.7270/Q2D50PW0	26502061			Fiore, M; Forli, S; Manetti, F	Universit&#163; di Siena	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50172066	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50172066&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			127043735	104058219		CHEMBL3808687				ZINC28528421	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50497641	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)nc2)C(=O)N1	InChI=1S/C21H18N4OS/c1-11-3-4-13(10-22-11)15-6-5-14-16(25-15)7-8-17-18(14)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1	CMWRPDHVGMHLSZ-GFCCVEGCSA-N	50395272	CHEMBL1231206	MAP kinase-activated protein kinase 2	Homo sapiens		 201							ChEMBL	10.1021/acs.jmedchem.5b01457	10.7270/Q2D50PW0	26502061			Fiore, M; Forli, S; Manetti, F	Universit&#163; di Siena	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395272&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B97	3FYJ,6T8X,7NRY	44631903	163344296		CHEMBL1231206	DB07430			ZINC39258365	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515278	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cccnc2)C(=O)N1	InChI=1S/C20H16N4OS/c1-11-9-22-18-17-13-4-5-14(12-3-2-8-21-10-12)24-15(13)6-7-16(17)26-19(18)20(25)23-11/h2-8,10-11,22H,9H2,1H3,(H,23,25)/t11-/m1/s1	TYUFCPFOZWXAQL-LLVKDONJSA-N	50297113	(R)-10-Methyl-3-pyridin-3-yl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL560075	MAP kinase-activated protein kinase 2	Homo sapiens		 220							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297113&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267583	104138644		CHEMBL560075				ZINC43119914	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515279	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cncnc2)C(=O)N1	InChI=1S/C19H15N5OS/c1-10-6-22-17-16-12-2-3-13(11-7-20-9-21-8-11)24-14(12)4-5-15(16)26-18(17)19(25)23-10/h2-5,7-10,22H,6H2,1H3,(H,23,25)/t10-/m1/s1	BOGPCCOCPGCUAT-SNVBAGLBSA-N	50297114	(R)-10-Methyl-3-pyrimidin-5-yl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL549585	MAP kinase-activated protein kinase 2	Homo sapiens		 640							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297114&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45270159	104138645		CHEMBL549585				ZINC43011202	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515280	COc1ccccc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H19N3O2S/c1-12-11-23-20-19-14-7-8-15(13-5-3-4-6-17(13)27-2)25-16(14)9-10-18(19)28-21(20)22(26)24-12/h3-10,12,23H,11H2,1-2H3,(H,24,26)/t12-/m1/s1	QZLQDTLFMZLLHY-GFCCVEGCSA-N	50297115	(R)-3-(2-Methoxy-phenyl)-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL562137	MAP kinase-activated protein kinase 2	Homo sapiens		 1040							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297115&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268471	104138646		CHEMBL562137				ZINC43079900	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515281	COc1cccc(c1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H19N3O2S/c1-12-11-23-20-19-15-6-7-16(13-4-3-5-14(10-13)27-2)25-17(15)8-9-18(19)28-21(20)22(26)24-12/h3-10,12,23H,11H2,1-2H3,(H,24,26)/t12-/m1/s1	IKAZZNSWVQMULP-GFCCVEGCSA-N	50297116	(R)-3-(3-Methoxy-phenyl)-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL563307	MAP kinase-activated protein kinase 2	Homo sapiens		 690							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297116&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269326	104138647		CHEMBL563307				ZINC43073077	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515282	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccccc2F)C(=O)N1	InChI=1S/C21H16FN3OS/c1-11-10-23-19-18-13-6-7-15(12-4-2-3-5-14(12)22)25-16(13)8-9-17(18)27-20(19)21(26)24-11/h2-9,11,23H,10H2,1H3,(H,24,26)/t11-/m1/s1	TXYQKEJLINYOCR-LLVKDONJSA-N	50297117	(R)-3-(2-Fluoro-phenyl)-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL554286	MAP kinase-activated protein kinase 2	Homo sapiens		 930							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297117&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271854	104138648		CHEMBL554286				ZINC43017521	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515283	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccccc2C)C(=O)N1	InChI=1S/C22H19N3OS/c1-12-5-3-4-6-14(12)16-8-7-15-17(25-16)9-10-18-19(15)20-21(27-18)22(26)24-13(2)11-23-20/h3-10,13,23H,11H2,1-2H3,(H,24,26)/t13-/m1/s1	LFNXZWVZXRCIBL-CYBMUJFWSA-N	50297118	(R)-10-Methyl-3-o-tolyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL562606	MAP kinase-activated protein kinase 2	Homo sapiens		 3360							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297118&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45272713	104138649		CHEMBL562606				ZINC43016705	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515284	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnccc2C)C(=O)N1	InChI=1S/C21H18N4OS/c1-11-7-8-22-10-14(11)16-4-3-13-15(25-16)5-6-17-18(13)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1	XXBIBHJGTXHGJL-GFCCVEGCSA-N	50297119	(R)-10-Methyl-3-(4-methyl-pyridin-3-yl)-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL549915	MAP kinase-activated protein kinase 2	Homo sapiens		 150							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297119&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271859	104138650		CHEMBL549915				ZINC43012280	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515285	COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C13H14N2O2S/c1-7-6-14-11-9-5-8(17-2)3-4-10(9)18-12(11)13(16)15-7/h3-5,7,14H,6H2,1-2H3,(H,15,16)/t7-/m1/s1	QAQKNZRNOQBKRE-SSDOTTSWSA-N	50119298	(R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL99780	MAP kinase-activated protein kinase 2	Homo sapiens		 40							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119298&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512562	104012525		CHEMBL99780				ZINC03647053	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515286	C[C@@H]1CNc2c(sc3ccc4occc4c23)C(=O)N1	InChI=1S/C14H12N2O2S/c1-7-6-15-12-11-8-4-5-18-9(8)2-3-10(11)19-13(12)14(17)16-7/h2-5,7,15H,6H2,1H3,(H,16,17)/t7-/m1/s1	FGQLPUTYZYTKLO-SSDOTTSWSA-N	50297120	(R)-9-Methyl-8,9,10,11-tetrahydro-3-oxa-6-thia-8,11-diaza-cyclohepta[b]-as-indacen-7-one::CHEMBL557318	MAP kinase-activated protein kinase 2	Homo sapiens		 16							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297120&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44517742	104138651		CHEMBL557318				ZINC43061719	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515287	C[C@@H]1CNc2c(sc3ccc4OCCc4c23)C(=O)N1	InChI=1S/C14H14N2O2S/c1-7-6-15-12-11-8-4-5-18-9(8)2-3-10(11)19-13(12)14(17)16-7/h2-3,7,15H,4-6H2,1H3,(H,16,17)/t7-/m1/s1	ZLCBGFVBDKXPBZ-SSDOTTSWSA-N	50297121	(R)-9-Methyl-1,2,8,9,10,11-hexahydro-3-oxa-6-thia-8,11-diaza-cyclohepta[b]-as-indacen-7-one::CHEMBL562754	MAP kinase-activated protein kinase 2	Homo sapiens		 28							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297121&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45272705	104138652		CHEMBL562754				ZINC43021393	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515288	C[C@@H]1CNc2c(sc3ccc4ncccc4c23)C(=O)N1	InChI=1S/C15H13N3OS/c1-8-7-17-13-12-9-3-2-6-16-10(9)4-5-11(12)20-14(13)15(19)18-8/h2-6,8,17H,7H2,1H3,(H,18,19)/t8-/m1/s1	BKMFUDJYEMHEKH-MRVPVSSYSA-N	50297122	(R)-10-Methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL561334	MAP kinase-activated protein kinase 2	Homo sapiens		 1							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297122&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44517741	104138653		CHEMBL561334				ZINC43019267	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515289	C[C@@H]1CNc2c(sc3ccc4oc(cc4c23)-c2ccccc2)C(=O)N1	InChI=1S/C20H16N2O2S/c1-11-10-21-18-17-13-9-15(12-5-3-2-4-6-12)24-14(13)7-8-16(17)25-19(18)20(23)22-11/h2-9,11,21H,10H2,1H3,(H,22,23)/t11-/m1/s1	HJSVRZBFKFCGAZ-LLVKDONJSA-N	50297123	(R)-9-Methyl-2-phenyl-8,9,10,11-tetrahydro-3-oxa-6-thia-8,11-diaza-cyclohepta[b]-as-indacen-7-one::CHEMBL562194	MAP kinase-activated protein kinase 2	Homo sapiens		 150							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297123&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269319	104138654		CHEMBL562194				ZINC43017232	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515290	C[C@@H]1CNc2c(sc3ccc4nc(Cl)ccc4c23)C(=O)N1	InChI=1S/C15H12ClN3OS/c1-7-6-17-13-12-8-2-5-11(16)19-9(8)3-4-10(12)21-14(13)15(20)18-7/h2-5,7,17H,6H2,1H3,(H,18,20)/t7-/m1/s1	OVJIHFBAXJKTRF-SSDOTTSWSA-N	50297124	(R)-3-Chloro-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL556392	MAP kinase-activated protein kinase 2	Homo sapiens		 2							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297124&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267582	104138655		CHEMBL556392				ZINC42966009	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515291	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccccc2)C(=O)N1	InChI=1S/C21H17N3OS/c1-12-11-22-19-18-14-7-8-15(13-5-3-2-4-6-13)24-16(14)9-10-17(18)26-20(19)21(25)23-12/h2-10,12,22H,11H2,1H3,(H,23,25)/t12-/m1/s1	LVKGEKFNCBTKTM-GFCCVEGCSA-N	50297125	(R)-10-Methyl-3-phenyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL564076	MAP kinase-activated protein kinase 2	Homo sapiens		 9							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297125&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271845	104138656		CHEMBL564076				ZINC43061440	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515295	COc1ccccc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H19N3O2S/c1-12-11-23-20-19-14-7-8-15(13-5-3-4-6-17(13)27-2)25-16(14)9-10-18(19)28-21(20)22(26)24-12/h3-10,12,23H,11H2,1-2H3,(H,24,26)/t12-/m1/s1	QZLQDTLFMZLLHY-GFCCVEGCSA-N	50297115	(R)-3-(2-Methoxy-phenyl)-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL562137	MAP kinase-activated protein kinase 2	Homo sapiens		 20							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297115&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268471	104138646		CHEMBL562137				ZINC43079900	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515296	COc1cccc(c1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H19N3O2S/c1-12-11-23-20-19-15-6-7-16(13-4-3-5-14(10-13)27-2)25-17(15)8-9-18(19)28-21(20)22(26)24-12/h3-10,12,23H,11H2,1-2H3,(H,24,26)/t12-/m1/s1	IKAZZNSWVQMULP-GFCCVEGCSA-N	50297116	(R)-3-(3-Methoxy-phenyl)-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL563307	MAP kinase-activated protein kinase 2	Homo sapiens		 41							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297116&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269326	104138647		CHEMBL563307				ZINC43073077	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515297	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccccc2F)C(=O)N1	InChI=1S/C21H16FN3OS/c1-11-10-23-19-18-13-6-7-15(12-4-2-3-5-14(12)22)25-16(13)8-9-17(18)27-20(19)21(26)24-11/h2-9,11,23H,10H2,1H3,(H,24,26)/t11-/m1/s1	TXYQKEJLINYOCR-LLVKDONJSA-N	50297117	(R)-3-(2-Fluoro-phenyl)-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL554286	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297117&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271854	104138648		CHEMBL554286				ZINC43017521	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515298	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccccc2C)C(=O)N1	InChI=1S/C22H19N3OS/c1-12-5-3-4-6-14(12)16-8-7-15-17(25-16)9-10-18-19(15)20-21(27-18)22(26)24-13(2)11-23-20/h3-10,13,23H,11H2,1-2H3,(H,24,26)/t13-/m1/s1	LFNXZWVZXRCIBL-CYBMUJFWSA-N	50297118	(R)-10-Methyl-3-o-tolyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL562606	MAP kinase-activated protein kinase 2	Homo sapiens		 30							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297118&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45272713	104138649		CHEMBL562606				ZINC43016705	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515299	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnccc2C)C(=O)N1	InChI=1S/C21H18N4OS/c1-11-7-8-22-10-14(11)16-4-3-13-15(25-16)5-6-17-18(13)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1	XXBIBHJGTXHGJL-GFCCVEGCSA-N	50297119	(R)-10-Methyl-3-(4-methyl-pyridin-3-yl)-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL549915	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297119&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271859	104138650		CHEMBL549915				ZINC43012280	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515315	COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C13H14N2O2S/c1-7-6-14-11-9-5-8(17-2)3-4-10(9)18-12(11)13(16)15-7/h3-5,7,14H,6H2,1-2H3,(H,15,16)/t7-/m1/s1	QAQKNZRNOQBKRE-SSDOTTSWSA-N	50119298	(R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL99780	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119298&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512562	104012525		CHEMBL99780				ZINC03647053	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515316	C[C@@H]1CNc2c(sc3ccc4occc4c23)C(=O)N1	InChI=1S/C14H12N2O2S/c1-7-6-15-12-11-8-4-5-18-9(8)2-3-10(11)19-13(12)14(17)16-7/h2-5,7,15H,6H2,1H3,(H,16,17)/t7-/m1/s1	FGQLPUTYZYTKLO-SSDOTTSWSA-N	50297120	(R)-9-Methyl-8,9,10,11-tetrahydro-3-oxa-6-thia-8,11-diaza-cyclohepta[b]-as-indacen-7-one::CHEMBL557318	MAP kinase-activated protein kinase 2	Homo sapiens		 90							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297120&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44517742	104138651		CHEMBL557318				ZINC43061719	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515317	C[C@@H]1CNc2c(sc3ccc4OCCc4c23)C(=O)N1	InChI=1S/C14H14N2O2S/c1-7-6-15-12-11-8-4-5-18-9(8)2-3-10(11)19-13(12)14(17)16-7/h2-3,7,15H,4-6H2,1H3,(H,16,17)/t7-/m1/s1	ZLCBGFVBDKXPBZ-SSDOTTSWSA-N	50297121	(R)-9-Methyl-1,2,8,9,10,11-hexahydro-3-oxa-6-thia-8,11-diaza-cyclohepta[b]-as-indacen-7-one::CHEMBL562754	MAP kinase-activated protein kinase 2	Homo sapiens		 260							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297121&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45272705	104138652		CHEMBL562754				ZINC43021393	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515318	C[C@@H]1CNc2c(sc3ccc4ncccc4c23)C(=O)N1	InChI=1S/C15H13N3OS/c1-8-7-17-13-12-9-3-2-6-16-10(9)4-5-11(12)20-14(13)15(19)18-8/h2-6,8,17H,7H2,1H3,(H,18,19)/t8-/m1/s1	BKMFUDJYEMHEKH-MRVPVSSYSA-N	50297122	(R)-10-Methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL561334	MAP kinase-activated protein kinase 2	Homo sapiens		 50							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297122&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44517741	104138653		CHEMBL561334				ZINC43019267	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515319	C[C@@H]1CNc2c(sc3ccc4oc(cc4c23)-c2ccccc2)C(=O)N1	InChI=1S/C20H16N2O2S/c1-11-10-21-18-17-13-9-15(12-5-3-2-4-6-12)24-14(13)7-8-16(17)25-19(18)20(23)22-11/h2-9,11,21H,10H2,1H3,(H,22,23)/t11-/m1/s1	HJSVRZBFKFCGAZ-LLVKDONJSA-N	50297123	(R)-9-Methyl-2-phenyl-8,9,10,11-tetrahydro-3-oxa-6-thia-8,11-diaza-cyclohepta[b]-as-indacen-7-one::CHEMBL562194	MAP kinase-activated protein kinase 2	Homo sapiens		 6800							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297123&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269319	104138654		CHEMBL562194				ZINC43017232	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515320	C[C@@H]1CNc2c(sc3ccc4nc(Cl)ccc4c23)C(=O)N1	InChI=1S/C15H12ClN3OS/c1-7-6-17-13-12-8-2-5-11(16)19-9(8)3-4-10(12)21-14(13)15(20)18-7/h2-5,7,17H,6H2,1H3,(H,18,20)/t7-/m1/s1	OVJIHFBAXJKTRF-SSDOTTSWSA-N	50297124	(R)-3-Chloro-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL556392	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297124&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267582	104138655		CHEMBL556392				ZINC42966009	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515321	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccccc2)C(=O)N1	InChI=1S/C21H17N3OS/c1-12-11-22-19-18-14-7-8-15(13-5-3-2-4-6-13)24-16(14)9-10-17(18)26-20(19)21(25)23-12/h2-10,12,22H,11H2,1H3,(H,23,25)/t12-/m1/s1	LVKGEKFNCBTKTM-GFCCVEGCSA-N	50297125	(R)-10-Methyl-3-phenyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL564076	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297125&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271845	104138656		CHEMBL564076				ZINC43061440	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515322	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccncc2)C(=O)N1	InChI=1S/C20H16N4OS/c1-11-10-22-18-17-13-2-3-14(12-6-8-21-9-7-12)24-15(13)4-5-16(17)26-19(18)20(25)23-11/h2-9,11,22H,10H2,1H3,(H,23,25)/t11-/m1/s1	DIJIJDANNOSBAG-LLVKDONJSA-N	50297126	(R)-10-Methyl-3-pyridin-4-yl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL552339	MAP kinase-activated protein kinase 2	Homo sapiens		 740							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297126&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271846	104138657		CHEMBL552339				ZINC43062269	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515350	CCNC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1	InChI=1S/C15H19N3O2S/c1-3-16-7-9-8-17-13-11-6-10(20-2)4-5-12(11)21-14(13)15(19)18-9/h4-6,9,16-17H,3,7-8H2,1-2H3,(H,18,19)/t9-/m1/s1	XOXRXPXQHFMGSV-SECBINFHSA-N	50297136	(R)-7-Ethylaminomethyl-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL550060	MAP kinase-activated protein kinase 2	Homo sapiens		 21600							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297136&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271022	104138667		CHEMBL550060				ZINC43011721	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515351	CCCNC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1	InChI=1S/C16H21N3O2S/c1-3-6-17-8-10-9-18-14-12-7-11(21-2)4-5-13(12)22-15(14)16(20)19-10/h4-5,7,10,17-18H,3,6,8-9H2,1-2H3,(H,19,20)/t10-/m1/s1	FHYKOYKLHAIARC-SNVBAGLBSA-N	50297137	(R)-3-Methoxy-7-propylaminomethyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL560737	MAP kinase-activated protein kinase 2	Homo sapiens		 450							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297137&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268501	104138668		CHEMBL560737				ZINC42923243	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515353	CCCNC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1	InChI=1S/C16H21N3O2S/c1-3-6-17-8-10-9-18-14-12-7-11(21-2)4-5-13(12)22-15(14)16(20)19-10/h4-5,7,10,17-18H,3,6,8-9H2,1-2H3,(H,19,20)/t10-/m1/s1	FHYKOYKLHAIARC-SNVBAGLBSA-N	50297137	(R)-3-Methoxy-7-propylaminomethyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL560737	MAP kinase-activated protein kinase 2	Homo sapiens		 14900							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297137&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268501	104138668		CHEMBL560737				ZINC42923243	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515354	COc1ccc2sc3c(NC[C@@H](CNCc4ccccc4)NC3=O)c2c1	InChI=1S/C20H21N3O2S/c1-25-15-7-8-17-16(9-15)18-19(26-17)20(24)23-14(12-22-18)11-21-10-13-5-3-2-4-6-13/h2-9,14,21-22H,10-12H2,1H3,(H,23,24)/t14-/m1/s1	UMTQCLJEOZEKRG-CQSZACIVSA-N	50297138	(R)-7-(Benzylamino-methyl)-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL551534	MAP kinase-activated protein kinase 2	Homo sapiens		 570							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297138&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271889	104138669		CHEMBL551534				ZINC43062907	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515356	COc1ccc2sc3c(NC[C@@H](CNCc4ccccc4)NC3=O)c2c1	InChI=1S/C20H21N3O2S/c1-25-15-7-8-17-16(9-15)18-19(26-17)20(24)23-14(12-22-18)11-21-10-13-5-3-2-4-6-13/h2-9,14,21-22H,10-12H2,1H3,(H,23,24)/t14-/m1/s1	UMTQCLJEOZEKRG-CQSZACIVSA-N	50297138	(R)-7-(Benzylamino-methyl)-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL551534	MAP kinase-activated protein kinase 2	Homo sapiens		 21000							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297138&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271889	104138669		CHEMBL551534				ZINC43062907	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515292	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccncc2)C(=O)N1	InChI=1S/C20H16N4OS/c1-11-10-22-18-17-13-2-3-14(12-6-8-21-9-7-12)24-15(13)4-5-16(17)26-19(18)20(25)23-11/h2-9,11,22H,10H2,1H3,(H,23,25)/t11-/m1/s1	DIJIJDANNOSBAG-LLVKDONJSA-N	50297126	(R)-10-Methyl-3-pyridin-4-yl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL552339	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297126&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271846	104138657		CHEMBL552339				ZINC43062269	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515293	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cccnc2)C(=O)N1	InChI=1S/C20H16N4OS/c1-11-9-22-18-17-13-4-5-14(12-3-2-8-21-10-12)24-15(13)6-7-16(17)26-19(18)20(25)23-11/h2-8,10-11,22H,9H2,1H3,(H,23,25)/t11-/m1/s1	TYUFCPFOZWXAQL-LLVKDONJSA-N	50297113	(R)-10-Methyl-3-pyridin-3-yl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL560075	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297113&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267583	104138644		CHEMBL560075				ZINC43119914	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515294	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cncnc2)C(=O)N1	InChI=1S/C19H15N5OS/c1-10-6-22-17-16-12-2-3-13(11-7-20-9-21-8-11)24-14(12)4-5-15(16)26-18(17)19(25)23-10/h2-5,7-10,22H,6H2,1H3,(H,23,25)/t10-/m1/s1	BOGPCCOCPGCUAT-SNVBAGLBSA-N	50297114	(R)-10-Methyl-3-pyrimidin-5-yl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one::CHEMBL549585	MAP kinase-activated protein kinase 2	Homo sapiens		 23							ChEMBL	10.1016/j.bmcl.2009.02.017	10.7270/Q2J38SM7	19616942			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ; Parikh, MD	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297114&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45270159	104138645		CHEMBL549585				ZINC43011202	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515357	COc1ccc2sc3c(NC[C@@H](CN4CCCC4)NC3=O)c2c1	InChI=1S/C17H21N3O2S/c1-22-12-4-5-14-13(8-12)15-16(23-14)17(21)19-11(9-18-15)10-20-6-2-3-7-20/h4-5,8,11,18H,2-3,6-7,9-10H2,1H3,(H,19,21)/t11-/m0/s1	HAYHOUOJSMEPFE-NSHDSACASA-N	50297139	(S)-3-Methoxy-7-pyrrolidin-1-ylmethyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL550260	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297139&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271028	104138670		CHEMBL550260				ZINC43013596	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515358	COc1ccc2sc3c(NC[C@@H](CN4CCOCC4)NC3=O)c2c1	InChI=1S/C17H21N3O3S/c1-22-12-2-3-14-13(8-12)15-16(24-14)17(21)19-11(9-18-15)10-20-4-6-23-7-5-20/h2-3,8,11,18H,4-7,9-10H2,1H3,(H,19,21)/t11-/m0/s1	WYNKVGUYVKMILG-NSHDSACASA-N	50297140	(S)-3-Methoxy-7-morpholin-4-ylmethyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL558162	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297140&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271890	104138671		CHEMBL558162				ZINC43061009	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515359	COc1ccc2sc3c(NC[C@@H](CN(C)Cc4ccccc4)NC3=O)c2c1	InChI=1S/C21H23N3O2S/c1-24(12-14-6-4-3-5-7-14)13-15-11-22-19-17-10-16(26-2)8-9-18(17)27-20(19)21(25)23-15/h3-10,15,22H,11-13H2,1-2H3,(H,23,25)/t15-/m0/s1	DJUGDBUCNZFFNS-HNNXBMFYSA-N	50297141	(S)-7-[(Benzyl-methyl-amino)-methyl]-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL562002	MAP kinase-activated protein kinase 2	Homo sapiens		 1910							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297141&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269365	104138672		CHEMBL562002				ZINC43077781	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515361	COc1ccc2sc3c(NC[C@@H](CN(C)Cc4ccccc4)NC3=O)c2c1	InChI=1S/C21H23N3O2S/c1-24(12-14-6-4-3-5-7-14)13-15-11-22-19-17-10-16(26-2)8-9-18(17)27-20(19)21(25)23-15/h3-10,15,22H,11-13H2,1-2H3,(H,23,25)/t15-/m0/s1	DJUGDBUCNZFFNS-HNNXBMFYSA-N	50297141	(S)-7-[(Benzyl-methyl-amino)-methyl]-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL562002	MAP kinase-activated protein kinase 2	Homo sapiens		 24000							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297141	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297141&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269365	104138672		CHEMBL562002				ZINC43077781	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515362	C[C@@H]1CNc2c(sc3ccc(O)cc23)C(=O)N1	InChI=1S/C12H12N2O2S/c1-6-5-13-10-8-4-7(15)2-3-9(8)17-11(10)12(16)14-6/h2-4,6,13,15H,5H2,1H3,(H,14,16)/t6-/m1/s1	GWODBBFDCZIKBY-ZCFIWIBFSA-N	50297142	(R)-3-Hydroxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL559487	MAP kinase-activated protein kinase 2	Homo sapiens		 190							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297142&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267633	104138673		CHEMBL559487				ZINC42922935	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515364	C[C@@H]1CNc2c(sc3ccc(O)cc23)C(=O)N1	InChI=1S/C12H12N2O2S/c1-6-5-13-10-8-4-7(15)2-3-9(8)17-11(10)12(16)14-6/h2-4,6,13,15H,5H2,1H3,(H,14,16)/t6-/m1/s1	GWODBBFDCZIKBY-ZCFIWIBFSA-N	50297142	(R)-3-Hydroxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL559487	MAP kinase-activated protein kinase 2	Homo sapiens		 3500							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297142	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297142&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267633	104138673		CHEMBL559487				ZINC42922935	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515365	COc1cccc(COc2ccc3sc4c(NC[C@@H](C)NC4=O)c3c2)c1	InChI=1S/C20H20N2O3S/c1-12-10-21-18-16-9-15(6-7-17(16)26-19(18)20(23)22-12)25-11-13-4-3-5-14(8-13)24-2/h3-9,12,21H,10-11H2,1-2H3,(H,22,23)/t12-/m1/s1	URPBNNONUNUVHW-GFCCVEGCSA-N	50297143	(R)-3-(3-Methoxy-benzyloxy)-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL541448	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297143&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269366	104138674		CHEMBL541448				ZINC42967247	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515367	COc1cccc(COc2ccc3sc4c(NC[C@@H](C)NC4=O)c3c2)c1	InChI=1S/C20H20N2O3S/c1-12-10-21-18-16-9-15(6-7-17(16)26-19(18)20(23)22-12)25-11-13-4-3-5-14(8-13)24-2/h3-9,12,21H,10-11H2,1-2H3,(H,22,23)/t12-/m1/s1	URPBNNONUNUVHW-GFCCVEGCSA-N	50297143	(R)-3-(3-Methoxy-benzyloxy)-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL541448	MAP kinase-activated protein kinase 2	Homo sapiens		 4600							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297143	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297143&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269366	104138674		CHEMBL541448				ZINC42967247	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515368	C[C@@H]1CNc2c(sc3ccc(OCC4CC4)cc23)C(=O)N1	InChI=1S/C16H18N2O2S/c1-9-7-17-14-12-6-11(20-8-10-2-3-10)4-5-13(12)21-15(14)16(19)18-9/h4-6,9-10,17H,2-3,7-8H2,1H3,(H,18,19)/t9-/m1/s1	UNTOEJWOGZGOAO-SECBINFHSA-N	50297144	(R)-3-Cyclopropylmethoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL563672	MAP kinase-activated protein kinase 2	Homo sapiens		 1320							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297144	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297144&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268513	104138675		CHEMBL563672				ZINC43020377	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515370	C[C@@H]1CNc2c(sc3ccc(OCC4CC4)cc23)C(=O)N1	InChI=1S/C16H18N2O2S/c1-9-7-17-14-12-6-11(20-8-10-2-3-10)4-5-13(12)21-15(14)16(19)18-9/h4-6,9-10,17H,2-3,7-8H2,1H3,(H,18,19)/t9-/m1/s1	UNTOEJWOGZGOAO-SECBINFHSA-N	50297144	(R)-3-Cyclopropylmethoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL563672	MAP kinase-activated protein kinase 2	Homo sapiens		 27000							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297144	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297144&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268513	104138675		CHEMBL563672				ZINC43020377	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515371	COCCOc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C15H18N2O3S/c1-9-8-16-13-11-7-10(20-6-5-19-2)3-4-12(11)21-14(13)15(18)17-9/h3-4,7,9,16H,5-6,8H2,1-2H3,(H,17,18)/t9-/m1/s1	KCXYHUJEGPMBKM-SECBINFHSA-N	50297145	(R)-3-(2-Methoxy-ethoxy)-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL559411	MAP kinase-activated protein kinase 2	Homo sapiens		 270							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297145&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269376	104138676		CHEMBL559411				ZINC43073965	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515373	COCCOc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C15H18N2O3S/c1-9-8-16-13-11-7-10(20-6-5-19-2)3-4-12(11)21-14(13)15(18)17-9/h3-4,7,9,16H,5-6,8H2,1-2H3,(H,17,18)/t9-/m1/s1	KCXYHUJEGPMBKM-SECBINFHSA-N	50297145	(R)-3-(2-Methoxy-ethoxy)-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL559411	MAP kinase-activated protein kinase 2	Homo sapiens		 3100							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297145	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297145&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269376	104138676		CHEMBL559411				ZINC43073965	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515374	CC(C)COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C16H20N2O2S/c1-9(2)8-20-11-4-5-13-12(6-11)14-15(21-13)16(19)18-10(3)7-17-14/h4-6,9-10,17H,7-8H2,1-3H3,(H,18,19)/t10-/m1/s1	JJQNDXCUJRPPDT-SNVBAGLBSA-N	50297146	(R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL563308	MAP kinase-activated protein kinase 2	Homo sapiens		 30							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297146&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44631900	104138677		CHEMBL563308				ZINC43073971	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515376	CC(C)COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C16H20N2O2S/c1-9(2)8-20-11-4-5-13-12(6-11)14-15(21-13)16(19)18-10(3)7-17-14/h4-6,9-10,17H,7-8H2,1-3H3,(H,18,19)/t10-/m1/s1	JJQNDXCUJRPPDT-SNVBAGLBSA-N	50297146	(R)-3-Isobutoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL563308	MAP kinase-activated protein kinase 2	Homo sapiens		 1800							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297146	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297146&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44631900	104138677		CHEMBL563308				ZINC43073971	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515377	COC(=O)COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C15H16N2O4S/c1-8-6-16-13-10-5-9(21-7-12(18)20-2)3-4-11(10)22-14(13)15(19)17-8/h3-5,8,16H,6-7H2,1-2H3,(H,17,19)/t8-/m1/s1	PCQUNTVDQZZICH-MRVPVSSYSA-N	50297147	((R)-7-Methyl-9-oxo-6,7,8,9-tetrahydro-5H-10-thia-5,8-diaza-benzo[a]azulen-3-yloxy)-acetic acid methyl ester::CHEMBL559881	MAP kinase-activated protein kinase 2	Homo sapiens		 3440							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297147&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267641	104138678		CHEMBL559881				ZINC43076507	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515379	COC(=O)COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C15H16N2O4S/c1-8-6-16-13-10-5-9(21-7-12(18)20-2)3-4-11(10)22-14(13)15(19)17-8/h3-5,8,16H,6-7H2,1-2H3,(H,17,19)/t8-/m1/s1	PCQUNTVDQZZICH-MRVPVSSYSA-N	50297147	((R)-7-Methyl-9-oxo-6,7,8,9-tetrahydro-5H-10-thia-5,8-diaza-benzo[a]azulen-3-yloxy)-acetic acid methyl ester::CHEMBL559881	MAP kinase-activated protein kinase 2	Homo sapiens		 78000							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297147	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297147&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267641	104138678		CHEMBL559881				ZINC43076507	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515380	COc1ccc2sc3c(NCCNC3=O)c2c1	InChI=1S/C12H12N2O2S/c1-16-7-2-3-9-8(6-7)10-11(17-9)12(15)14-5-4-13-10/h2-3,6,13H,4-5H2,1H3,(H,14,15)	YLQOELRYUQBERL-UHFFFAOYSA-N	50119283	3-Methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL319171	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119283&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512549	104012523		CHEMBL319171				ZINC00002980	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515382	COc1ccc2sc3c(NCCNC3=O)c2c1	InChI=1S/C12H12N2O2S/c1-16-7-2-3-9-8(6-7)10-11(17-9)12(15)14-5-4-13-10/h2-3,6,13H,4-5H2,1H3,(H,14,15)	YLQOELRYUQBERL-UHFFFAOYSA-N	50119283	3-Methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL319171	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119283&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512549	104012523		CHEMBL319171				ZINC00002980	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515383	COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C13H14N2O2S/c1-7-6-14-11-9-5-8(17-2)3-4-10(9)18-12(11)13(16)15-7/h3-5,7,14H,6H2,1-2H3,(H,15,16)/t7-/m1/s1	QAQKNZRNOQBKRE-SSDOTTSWSA-N	50119298	(R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL99780	MAP kinase-activated protein kinase 2	Homo sapiens		 40							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119298&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512562	104012525		CHEMBL99780				ZINC03647053	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515385	COc1ccc2sc3c(NC[C@@H](C)NC3=O)c2c1	InChI=1S/C13H14N2O2S/c1-7-6-14-11-9-5-8(17-2)3-4-10(9)18-12(11)13(16)15-7/h3-5,7,14H,6H2,1-2H3,(H,15,16)/t7-/m1/s1	QAQKNZRNOQBKRE-SSDOTTSWSA-N	50119298	(R)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL99780	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119298&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512562	104012525		CHEMBL99780				ZINC03647053	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515386	COc1ccc2sc3c(NC[C@H](C)NC3=O)c2c1	InChI=1S/C13H14N2O2S/c1-7-6-14-11-9-5-8(17-2)3-4-10(9)18-12(11)13(16)15-7/h3-5,7,14H,6H2,1-2H3,(H,15,16)/t7-/m0/s1	QAQKNZRNOQBKRE-ZETCQYMHSA-N	50119279	(S)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL100818	MAP kinase-activated protein kinase 2	Homo sapiens		 300							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119279&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512561	104012522		CHEMBL100818				ZINC03647052	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515388	COc1ccc2sc3c(NC[C@H](C)NC3=O)c2c1	InChI=1S/C13H14N2O2S/c1-7-6-14-11-9-5-8(17-2)3-4-10(9)18-12(11)13(16)15-7/h3-5,7,14H,6H2,1-2H3,(H,15,16)/t7-/m0/s1	QAQKNZRNOQBKRE-ZETCQYMHSA-N	50119279	(S)-3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::3-Methoxy-7-methyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL100818	MAP kinase-activated protein kinase 2	Homo sapiens		 3800							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119279&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			512561	104012522		CHEMBL100818				ZINC03647052	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515389	CCC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1	InChI=1S/C15H18N2O2S/c1-3-4-9-8-16-13-11-7-10(19-2)5-6-12(11)20-14(13)15(18)17-9/h5-7,9,16H,3-4,8H2,1-2H3,(H,17,18)/t9-/m1/s1	XXIHHKWKHPBCOE-SECBINFHSA-N	50297148	(R)-3-Methoxy-7-propyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL539450	MAP kinase-activated protein kinase 2	Homo sapiens		 1520							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297148&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271878	104138679		CHEMBL539450				ZINC42989355	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515390	CCC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1	InChI=1S/C15H18N2O2S/c1-3-4-9-8-16-13-11-7-10(19-2)5-6-12(11)20-14(13)15(18)17-9/h5-7,9,16H,3-4,8H2,1-2H3,(H,17,18)/t9-/m1/s1	XXIHHKWKHPBCOE-SECBINFHSA-N	50297148	(R)-3-Methoxy-7-propyl-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL539450	MAP kinase-activated protein kinase 2	Homo sapiens		 5450							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297148	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297148&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271878	104138679		CHEMBL539450				ZINC42989355	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515391	COc1ccc2sc3c(NC[C@@H](CO)NC3=O)c2c1	InChI=1S/C13H14N2O3S/c1-18-8-2-3-10-9(4-8)11-12(19-10)13(17)15-7(6-16)5-14-11/h2-4,7,14,16H,5-6H2,1H3,(H,15,17)/t7-/m0/s1	DXXJDEVFDVVIGG-ZETCQYMHSA-N	50297149	(S)-7-Hydroxymethyl-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL553397	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297149	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297149&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268500	104138680		CHEMBL553397				ZINC42963744	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515393	COc1ccc2sc3c(NC[C@@H](CO)NC3=O)c2c1	InChI=1S/C13H14N2O3S/c1-18-8-2-3-10-9(4-8)11-12(19-10)13(17)15-7(6-16)5-14-11/h2-4,7,14,16H,5-6H2,1H3,(H,15,17)/t7-/m0/s1	DXXJDEVFDVVIGG-ZETCQYMHSA-N	50297149	(S)-7-Hydroxymethyl-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL553397	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297149	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297149&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45268500	104138680		CHEMBL553397				ZINC42963744	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515394	COc1ccc2sc3c(SCCNC3=O)c2c1	InChI=1S/C12H11NO2S2/c1-15-7-2-3-9-8(6-7)10-11(17-9)12(14)13-4-5-16-10/h2-3,6H,4-5H2,1H3,(H,13,14)	KGMSYXGSYGEHIS-UHFFFAOYSA-N	50119286	3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a]azulen-9-one::CHEMBL319170::PD-146626::kb-NB165-09	MAP kinase-activated protein kinase 2	Homo sapiens		 1090							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119286&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			461195	104012524		CHEMBL319170				ZINC00006473	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515396	COc1ccc2sc3c(SCCNC3=O)c2c1	InChI=1S/C12H11NO2S2/c1-15-7-2-3-9-8(6-7)10-11(17-9)12(14)13-4-5-16-10/h2-3,6H,4-5H2,1H3,(H,13,14)	KGMSYXGSYGEHIS-UHFFFAOYSA-N	50119286	3-Methoxy-7,8-dihydro-6H-5,10-dithia-8-aza-benzo[a]azulen-9-one::CHEMBL319170::PD-146626::kb-NB165-09	MAP kinase-activated protein kinase 2	Homo sapiens		 5500							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50119286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50119286&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			461195	104012524		CHEMBL319170				ZINC00006473	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515397	COc1ccc2sc3c(CCCNC3=O)c2c1	InChI=1S/C13H13NO2S/c1-16-8-4-5-11-10(7-8)9-3-2-6-14-13(15)12(9)17-11/h4-5,7H,2-3,6H2,1H3,(H,14,15)	BZQVWTDKMSTNBU-UHFFFAOYSA-N	50297150	3-Methoxy-5,6,7,8-tetrahydro-10-thia-8-aza-benzo[a]azulen-9-one::CHEMBL571897	MAP kinase-activated protein kinase 2	Homo sapiens		 500							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297150&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271879	104138681		CHEMBL571897				ZINC43022234	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515399	COc1ccc2sc3c(CCCNC3=O)c2c1	InChI=1S/C13H13NO2S/c1-16-8-4-5-11-10(7-8)9-3-2-6-14-13(15)12(9)17-11/h4-5,7H,2-3,6H2,1H3,(H,14,15)	BZQVWTDKMSTNBU-UHFFFAOYSA-N	50297150	3-Methoxy-5,6,7,8-tetrahydro-10-thia-8-aza-benzo[a]azulen-9-one::CHEMBL571897	MAP kinase-activated protein kinase 2	Homo sapiens		 4700							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297150	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297150&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271879	104138681		CHEMBL571897				ZINC43022234	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515400	COc1ccc2sc3c(NC[C@@H](CN)NC3=O)c2c1	InChI=1S/C13H15N3O2S/c1-18-8-2-3-10-9(4-8)11-12(19-10)13(17)16-7(5-14)6-15-11/h2-4,7,15H,5-6,14H2,1H3,(H,16,17)/t7-/m1/s1	TXYKBKYDFZQOCB-SSDOTTSWSA-N	50297151	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one::(R)-7-Aminomethyl-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL555205	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297151&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B98	3FYK,3FZ1	45273683	104138682		CHEMBL555205	DB07431			ZINC39258537	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515402	COc1ccc2sc3c(NC[C@@H](CN)NC3=O)c2c1	InChI=1S/C13H15N3O2S/c1-18-8-2-3-10-9(4-8)11-12(19-10)13(17)16-7(5-14)6-15-11/h2-4,7,15H,5-6,14H2,1H3,(H,16,17)/t7-/m1/s1	TXYKBKYDFZQOCB-SSDOTTSWSA-N	50297151	(3R)-3-(aminomethyl)-9-methoxy-1,2,3,4-tetrahydro-5H-[1]benzothieno[3,2-e][1,4]diazepin-5-one::(R)-7-Aminomethyl-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL555205	MAP kinase-activated protein kinase 2	Homo sapiens		 2600							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297151	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297151&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B98	3FYK,3FZ1	45273683	104138682		CHEMBL555205	DB07431			ZINC39258537	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50515403	CCNC[C@@H]1CNc2c(sc3ccc(OC)cc23)C(=O)N1	InChI=1S/C15H19N3O2S/c1-3-16-7-9-8-17-13-11-6-10(20-2)4-5-12(11)21-14(13)15(19)18-9/h4-6,9,16-17H,3,7-8H2,1-2H3,(H,18,19)/t9-/m1/s1	XOXRXPXQHFMGSV-SECBINFHSA-N	50297136	(R)-7-Ethylaminomethyl-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one::CHEMBL550060	MAP kinase-activated protein kinase 2	Homo sapiens		 570							ChEMBL	10.1016/j.bmcl.2009.02.015	10.7270/Q28K795K	19616945			Anderson, DR; Meyers, MJ; Kurumbail, RG; Caspers, N; Poda, GI; Long, SA; Pierce, BS; Mahoney, MW; Mourey, RJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50297136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50297136&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45271022	104138667		CHEMBL550060				ZINC43011721	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50512174	O[C@@H]1Cn2c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n(C[C@@H]1O)c4c23	InChI=1S/C24H19N3O3/c28-17-10-26-15-7-3-1-5-12(15)19-14-9-25-24(30)21(14)20-13-6-2-4-8-16(13)27(11-18(17)29)23(20)22(19)26/h1-8,17-18,28-29H,9-11H2,(H,25,30)/t17-,18+/m1/s1	BZSUCLDZAQTFQJ-MSOLQXFVSA-N	50295809	12,13-(2,3-Cis-dihyroxy-1,4-butyl)-6,7,12,13-tetrahydro-5-oxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole::CHEMBL559787	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL	10.1016/j.bmcl.2009.04.039	10.7270/Q2ZK5GQ8	19427203			Wilson, LJ; Malaviya, R; Yang, C; Argentieri, R; Wang, B; Chen, X; Murray, WV; Cavender, D	Johnson & Johnson Pharmaceutical Research & Development LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295809&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45269074	104137340		CHEMBL559787				ZINC43120444	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50512200	CC(=O)C1=CCn2c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n(C1)c4c23	InChI=1S/C26H17N3O3/c1-13(30)14-10-11-28-17-8-4-2-6-15(17)19-21-22(26(32)27-25(21)31)20-16-7-3-5-9-18(16)29(12-14)24(20)23(19)28/h2-10H,11-12H2,1H3,(H,27,31,32)	NYZNNKMKRXQWHA-UHFFFAOYSA-N	50295810	12,13-[2-carbomethoxy-1,4-but-cis-2-enyl]-6,7,12,13-tetrahyhydro-5,7-dioxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole::CHEMBL557101	MAP kinase-activated protein kinase 2	Homo sapiens		 540							ChEMBL	10.1016/j.bmcl.2009.04.039	10.7270/Q2ZK5GQ8	19427203			Wilson, LJ; Malaviya, R; Yang, C; Argentieri, R; Wang, B; Chen, X; Murray, WV; Cavender, D	Johnson & Johnson Pharmaceutical Research & Development LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295810&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45273358	104137341		CHEMBL557101				ZINC42989957	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50512201	COC(=O)[C@]1(O)Cn2c3ccccc3c3c4C(=O)NC(=O)c4c4c5ccccc5n(C[C@H]1O)c4c23	InChI=1S/C26H19N3O6/c1-35-25(33)26(34)11-29-15-9-5-3-7-13(15)18-20-19(23(31)27-24(20)32)17-12-6-2-4-8-14(12)28(10-16(26)30)21(17)22(18)29/h2-9,16,30,34H,10-11H2,1H3,(H,27,31,32)/t16-,26+/m1/s1	DMECWJSRBVZTGX-DXPJPUQTSA-N	50295811	12,13-[2-carboxymethyl-cis-2,3-dihydroxy)-1,4-butyl]-6,7,12,13-tetrahyhydro-5,7-dioxo-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole::CHEMBL564940	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL	10.1016/j.bmcl.2009.04.039	10.7270/Q2ZK5GQ8	19427203			Wilson, LJ; Malaviya, R; Yang, C; Argentieri, R; Wang, B; Chen, X; Murray, WV; Cavender, D	Johnson & Johnson Pharmaceutical Research & Development LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50295811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50295811&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45267327	104137342		CHEMBL564940				ZINC43011572	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546276	Nc1nccc(Nc2ccc3[nH]ncc3c2)n1	InChI=1S/C11H10N6/c12-11-13-4-3-10(16-11)15-8-1-2-9-7(5-8)6-14-17-9/h1-6H,(H,14,17)(H3,12,13,15,16)	NPMHMBDYTAGTEV-UHFFFAOYSA-N	50304991	CHEMBL584423::N4-(1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 24000							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304991&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224689	104159352		CHEMBL584423				ZINC45303323	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546277	Nc1nccc(Nc2ccc3[nH]nc(I)c3c2)n1	InChI=1S/C11H9IN6/c12-10-7-5-6(1-2-8(7)17-18-10)15-9-3-4-14-11(13)16-9/h1-5H,(H,17,18)(H3,13,14,15,16)	PRGFYUBQSMZPNY-UHFFFAOYSA-N	50304992	CHEMBL584617::N4-(3-iodo-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 14000							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304992&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224694	104159353		CHEMBL584617				ZINC45315378	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546278	Nc1nccc(Nc2cc(-c3ccsc3)c3[nH]ncc3c2)n1	InChI=1S/C15H12N6S/c16-15-17-3-1-13(20-15)19-11-5-10-7-18-21-14(10)12(6-11)9-2-4-22-8-9/h1-8H,(H,18,21)(H3,16,17,19,20)	PJTADZPJMSFJHE-UHFFFAOYSA-N	50304993	CHEMBL591328::N4-(7-(thiophen-3-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 5400							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304993&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224700	104159354		CHEMBL591328				ZINC45336989	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546279	Nc1nccc(Nc2cc(-c3ccc4ccccc4c3)c3[nH]ncc3c2)n1	InChI=1S/C21H16N6/c22-21-23-8-7-19(26-21)25-17-10-16-12-24-27-20(16)18(11-17)15-6-5-13-3-1-2-4-14(13)9-15/h1-12H,(H,24,27)(H3,22,23,25,26)	QFBSSUZRFADVOK-UHFFFAOYSA-N	50304994	CHEMBL589650::N4-(7-(naphthalen-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 720							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304994&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224666	104159355		CHEMBL589650				ZINC45337612	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546280	Nc1nccc(Nc2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)n1	InChI=1S/C19H14N6S/c20-19-21-6-5-17(24-19)23-13-7-12-10-22-25-18(12)14(9-13)16-8-11-3-1-2-4-15(11)26-16/h1-10H,(H,22,25)(H3,20,21,23,24)	XWCMINXOFGQDEA-UHFFFAOYSA-N	50304995	CHEMBL591305::N4-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 1600							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304995&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224674	104159356		CHEMBL591305				ZINC45339224	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546281	Nc1nccc(Nc2cc(-c3cc4ccccc4o3)c3[nH]ncc3c2)n1	InChI=1S/C19H14N6O/c20-19-21-6-5-17(24-19)23-13-7-12-10-22-25-18(12)14(9-13)16-8-11-3-1-2-4-15(11)26-16/h1-10H,(H,22,25)(H3,20,21,23,24)	IQDDLNJTLVXFQA-UHFFFAOYSA-N	50304996	CHEMBL590110::N4-(7-(benzofuran-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine::N~4~-[7-(1-benzofuran-2-yl)-1H-indazol-5-yl]pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 1300							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304996&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MK2	3KC3	44543658	104159357		CHEMBL590110				ZINC44460337	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546282	Nc1nccc(Nc2cc(I)c3[nH]ncc3c2)n1	InChI=1S/C11H9IN6/c12-8-4-7(3-6-5-15-18-10(6)8)16-9-1-2-14-11(13)17-9/h1-5H,(H,15,18)(H3,13,14,16,17)	FOIYZNZAROTCFF-UHFFFAOYSA-N	50304997	CHEMBL585958::N4-(7-iodo-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 9100							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304997&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224686	104159358		CHEMBL585958				ZINC45335028	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546283	Nc1nccc(Nc2ccc3[nH]nc(-c4ccsc4)c3c2)n1	InChI=1S/C15H12N6S/c16-15-17-5-3-13(19-15)18-10-1-2-12-11(7-10)14(21-20-12)9-4-6-22-8-9/h1-8H,(H,20,21)(H3,16,17,18,19)	HGKSWPMTSBTIJQ-UHFFFAOYSA-N	50304998	CHEMBL589626::N4-(3-(thiophen-3-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 3400							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304998	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304998&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224690	104159359		CHEMBL589626				ZINC45335944	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546284	Nc1nccc(Nc2ccc3[nH]nc(-c4ccc5ccccc5c4)c3c2)n1	InChI=1S/C21H16N6/c22-21-23-10-9-19(25-21)24-16-7-8-18-17(12-16)20(27-26-18)15-6-5-13-3-1-2-4-14(13)11-15/h1-12H,(H,26,27)(H3,22,23,24,25)	IZXPFVIQVFQGBQ-UHFFFAOYSA-N	50304999	CHEMBL590834::N4-(3-(naphthalen-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 310							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50304999	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50304999&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224682	104159360		CHEMBL590834				ZINC45339421	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546285	Nc1nccc(Nc2ccc3[nH]nc(-c4cc5ccccc5s4)c3c2)n1	InChI=1S/C19H14N6S/c20-19-21-8-7-17(23-19)22-12-5-6-14-13(10-12)18(25-24-14)16-9-11-3-1-2-4-15(11)26-16/h1-10H,(H,24,25)(H3,20,21,22,23)	LKOUCBSSBZXDFY-UHFFFAOYSA-N	50305000	CHEMBL600081::N4-(3-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 160							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305000&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224695	104159361		CHEMBL600081				ZINC45371518	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546286	Nc1nccc(Nc2ccc3[nH]nc(-c4ccc[nH]4)c3c2)n1	InChI=1S/C15H13N7/c16-15-18-7-5-13(20-15)19-9-3-4-11-10(8-9)14(22-21-11)12-2-1-6-17-12/h1-8,17H,(H,21,22)(H3,16,18,19,20)	GUCGAGSVDISAAV-UHFFFAOYSA-N	50305001	CHEMBL592288::N4-(3-(1H-pyrrol-2-yl)-1H-indazol-5-yl)pyrimidine-2,4-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		 160							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305001&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224667	104159362		CHEMBL592288				ZINC45339490	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546287	Nc1ncc2[nH]cc(-c3ccc4n[nH]cc4c3)c2n1	InChI=1S/C13H10N6/c14-13-16-6-11-12(18-13)9(5-15-11)7-1-2-10-8(3-7)4-17-19-10/h1-6,15H,(H,17,19)(H2,14,16,18)	YUOAHRDCBUETRH-UHFFFAOYSA-N	50305002	7-(1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL591071	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305002&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224671	104159363		CHEMBL591071				ZINC45338971	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546288	Nc1ncc2[nH]cc(-c3cc(-c4cc5ccccc5s4)c4n[nH]cc4c3)c2n1	InChI=1S/C21H14N6S/c22-21-24-10-16-20(26-21)15(9-23-16)12-5-13-8-25-27-19(13)14(6-12)18-7-11-3-1-2-4-17(11)28-18/h1-10,23H,(H,25,27)(H2,22,24,26)	UFEDSAVXRGQCQV-UHFFFAOYSA-N	50305003	7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL591797	MAP kinase-activated protein kinase 2	Homo sapiens		 56							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305003&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224696	104159364		CHEMBL591797				ZINC45338811	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546289	Nc1ncc2ccn(-c3ccc4[nH]ncc4c3)c2n1	InChI=1S/C13H10N6/c14-13-15-6-8-3-4-19(12(8)17-13)10-1-2-11-9(5-10)7-16-18-11/h1-7H,(H,16,18)(H2,14,15,17)	ZSWJIMAKJQWETI-UHFFFAOYSA-N	50305004	7-(1H-indazol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine::CHEMBL584640	MAP kinase-activated protein kinase 2	Homo sapiens		 49000							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305004&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224703	104159365		CHEMBL584640				ZINC45318557	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546290	Cn1cc(-c2ccc3[nH]ncc3c2)c2nc(N)ncc12	InChI=1S/C14H12N6/c1-20-7-10(13-12(20)6-16-14(15)18-13)8-2-3-11-9(4-8)5-17-19-11/h2-7H,1H3,(H,17,19)(H2,15,16,18)	KFTQIFQTWCAPPQ-UHFFFAOYSA-N	50305005	7-(1H-indazol-5-yl)-5-methyl-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL589853	MAP kinase-activated protein kinase 2	Homo sapiens		 1900							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305005&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224675	104159366		CHEMBL589853				ZINC45339597	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546291	NCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc12	InChI=1S/C23H19N7S/c24-5-6-30-12-17(22-18(30)11-26-23(25)28-22)14-7-15-10-27-29-21(15)16(8-14)20-9-13-3-1-2-4-19(13)31-20/h1-4,7-12H,5-6,24H2,(H,27,29)(H2,25,26,28)	JPOSFPUHBHRUAX-UHFFFAOYSA-N	50305006	5-(2-aminoethyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL590109	MAP kinase-activated protein kinase 2	Homo sapiens		 19							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305006&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224684	104159367		CHEMBL590109				ZINC45335993	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546292	NCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc12	InChI=1S/C24H21N7S/c25-6-3-7-31-13-18(23-19(31)12-27-24(26)29-23)15-8-16-11-28-30-22(16)17(9-15)21-10-14-4-1-2-5-20(14)32-21/h1-2,4-5,8-13H,3,6-7,25H2,(H,28,30)(H2,26,27,29)	LRZYYIZFBXFSJB-UHFFFAOYSA-N	50305007	5-(3-aminopropyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL592030	MAP kinase-activated protein kinase 2	Homo sapiens		 35							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305007&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224697	104159368		CHEMBL592030				ZINC45338837	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546293	NCCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc12	InChI=1S/C25H23N7S/c26-7-3-4-8-32-14-19(24-20(32)13-28-25(27)30-24)16-9-17-12-29-31-23(17)18(10-16)22-11-15-5-1-2-6-21(15)33-22/h1-2,5-6,9-14H,3-4,7-8,26H2,(H,29,31)(H2,27,28,30)	GVHJLQKEXAWMLD-UHFFFAOYSA-N	50305008	5-(4-aminobutyl)-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL591329	MAP kinase-activated protein kinase 2	Homo sapiens		 260							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305008&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224701	104159369		CHEMBL591329				ZINC45336991	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546294	Nc1ncc2n(CCC3CCNCC3)cc(-c3cc(-c4cc5ccccc5s4)c4[nH]ncc4c3)c2n1	InChI=1S/C28H27N7S/c29-28-31-15-23-27(33-28)22(16-35(23)10-7-17-5-8-30-9-6-17)19-11-20-14-32-34-26(20)21(12-19)25-13-18-3-1-2-4-24(18)36-25/h1-4,11-17,30H,5-10H2,(H,32,34)(H2,29,31,33)	USFSEVLTPLUQBS-UHFFFAOYSA-N	50305009	7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-(2-(piperidin-4-yl)ethyl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL592031	MAP kinase-activated protein kinase 2	Homo sapiens		 960							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305009&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224698	104159370		CHEMBL592031				ZINC45338839	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546295	Nc1ncc2n(CCCO)cc(-c3cc(-c4cc5ccccc5s4)c4[nH]ncc4c3)c2n1	InChI=1S/C24H20N6OS/c25-24-26-12-19-23(28-24)18(13-30(19)6-3-7-31)15-8-16-11-27-29-22(16)17(9-15)21-10-14-4-1-2-5-20(14)32-21/h1-2,4-5,8-13,31H,3,6-7H2,(H,27,29)(H2,25,26,28)	HWXHSZQIVLBJNL-UHFFFAOYSA-N	50305010	3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)propan-1-ol::CHEMBL590612	MAP kinase-activated protein kinase 2	Homo sapiens		 37							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305010&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224704	104159371		CHEMBL590612				ZINC45336692	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546296	COCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc12	InChI=1S/C25H22N6OS/c1-32-8-4-7-31-14-19(24-20(31)13-27-25(26)29-24)16-9-17-12-28-30-23(17)18(10-16)22-11-15-5-2-3-6-21(15)33-22/h2-3,5-6,9-14H,4,7-8H2,1H3,(H,28,30)(H2,26,27,29)	JMTSNXAVVBUXPQ-UHFFFAOYSA-N	50305011	7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-(3-methoxypropyl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL591783	MAP kinase-activated protein kinase 2	Homo sapiens		 820							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305011&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46224679	104159372		CHEMBL591783				ZINC45337743	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546297	Nc1ncc2n(CC(O)=O)cc(-c3cc(-c4cc5ccccc5s4)c4[nH]ncc4c3)c2n1	InChI=1S/C23H16N6O2S/c24-23-25-9-17-22(27-23)16(10-29(17)11-20(30)31)13-5-14-8-26-28-21(14)15(6-13)19-7-12-3-1-2-4-18(12)32-19/h1-10H,11H2,(H,26,28)(H,30,31)(H2,24,25,27)	GTYGWZPPLHEGPU-UHFFFAOYSA-N	50305012	2-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)acetic acid::CHEMBL596588	MAP kinase-activated protein kinase 2	Homo sapiens		 1900							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305012&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46226037	104159373		CHEMBL596588				ZINC45367454	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546298	Nc1ncc2n(CCC(O)=O)cc(-c3cc(-c4cc5ccccc5s4)c4[nH]ncc4c3)c2n1	InChI=1S/C24H18N6O2S/c25-24-26-11-18-23(28-24)17(12-30(18)6-5-21(31)32)14-7-15-10-27-29-22(15)16(8-14)20-9-13-3-1-2-4-19(13)33-20/h1-4,7-12H,5-6H2,(H,27,29)(H,31,32)(H2,25,26,28)	VLYGLHMZWHBDED-UHFFFAOYSA-N	50305013	3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)propanoic acid::CHEMBL594090	MAP kinase-activated protein kinase 2	Homo sapiens		 20							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305013&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46226047	104159374		CHEMBL594090				ZINC45348371	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546299	NC(=O)CCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc12	InChI=1S/C24H19N7OS/c25-21(32)5-6-31-12-17(23-18(31)11-27-24(26)29-23)14-7-15-10-28-30-22(15)16(8-14)20-9-13-3-1-2-4-19(13)33-20/h1-4,7-12H,5-6H2,(H2,25,32)(H,28,30)(H2,26,27,29)	ZVWDYPREWNIILN-UHFFFAOYSA-N	50305014	3-(2-amino-7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5H-pyrrolo[3,2-d]pyrimidin-5-yl)propanamide::CHEMBL603322	MAP kinase-activated protein kinase 2	Homo sapiens		 41							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305014&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46226048	104159375		CHEMBL603322				ZINC45375205	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546300	Nc1ncc2n(cc(-c3cc(-c4cc5ccccc5s4)c4[nH]ncc4c3)c2n1)C1C=CC=C1	InChI=1S/C26H18N6S/c27-26-28-13-21-25(30-26)20(14-32(21)18-6-2-3-7-18)16-9-17-12-29-31-24(17)19(10-16)23-11-15-5-1-4-8-22(15)33-23/h1-14,18H,(H,29,31)(H2,27,28,30)	PFDRBOSPJOVHCV-UHFFFAOYSA-N	50305015	7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-(cyclopenta-2,4-dienyl)-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL605922	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305015&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46226031	104159376		CHEMBL605922				ZINC45386618	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546301	CC(C)n1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc12	InChI=1S/C24H20N6S/c1-13(2)30-12-18(23-19(30)11-26-24(25)28-23)15-7-16-10-27-29-22(16)17(8-15)21-9-14-5-3-4-6-20(14)31-21/h3-13H,1-2H3,(H,27,29)(H2,25,26,28)	PHVKYRWCTDTIMS-UHFFFAOYSA-N	50305016	7-(7-(benzo[b]thiophen-2-yl)-1H-indazol-5-yl)-5-isopropyl-5H-pyrrolo[3,2-d]pyrimidin-2-amine::CHEMBL595933	MAP kinase-activated protein kinase 2	Homo sapiens		 490							ChEMBL	10.1016/j.bmcl.2009.10.103	10.7270/Q2VD6ZJJ	19926477			Harris, CM; Ericsson, AM; Argiriadi, MA; Barberis, C; Borhani, DW; Burchat, A; Calderwood, DJ; Cunha, GA; Dixon, RW; Frank, KE; Johnson, EF; Kamens, J; Kwak, S; Li, B; Mullen, KD; Perron, DC; Wang, L; Wishart, N; Wu, X; Zhang, X; Zmetra, TR; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50305016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50305016&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46226038	104159377		CHEMBL595933				ZINC45349698	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50551769	CC(=O)N1CCC(CC1)Nc1ncc2CCc3c(nn(C)c3-c2n1)C(N)=O	InChI=1S/C18H23N7O2/c1-10(26)25-7-5-12(6-8-25)21-18-20-9-11-3-4-13-15(17(19)27)23-24(2)16(13)14(11)22-18/h9,12H,3-8H2,1-2H3,(H2,19,27)(H,20,21,22)	CQWBHMMWZICZRH-UHFFFAOYSA-N	50307535	8-[(1-Acetylpiperidin-4-yl)amino]-1-methyl-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide::CHEMBL599224	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm901710h	10.7270/Q2N879W9	20141146			Traquandi, G; Ciomei, M; Ballinari, D; Casale, E; Colombo, N; Croci, V; Fiorentini, F; Isacchi, A; Longo, A; Mercurio, C; Panzeri, A; Pastori, W; Pevarello, P; Volpi, D; Roussel, P; Vulpetti, A; Brasca, MG	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307535&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45139989	104161896		CHEMBL599224				ZINC45356657	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50551771	Cn1nc(C(N)=O)c2CCc3cnc(NC4CCN(CC4)C(=O)c4ccccc4)nc3-c12	InChI=1S/C23H25N7O2/c1-29-20-17(19(28-29)21(24)31)8-7-15-13-25-23(27-18(15)20)26-16-9-11-30(12-10-16)22(32)14-5-3-2-4-6-14/h2-6,13,16H,7-12H2,1H3,(H2,24,31)(H,25,26,27)	DIASEXMEBNQQHZ-UHFFFAOYSA-N	50307506	1-Methyl-8-{[1-(phenylcarbonyl)piperidin-4-yl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide::CHEMBL599428	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm901710h	10.7270/Q2N879W9	20141146			Traquandi, G; Ciomei, M; Ballinari, D; Casale, E; Colombo, N; Croci, V; Fiorentini, F; Isacchi, A; Longo, A; Mercurio, C; Panzeri, A; Pastori, W; Pevarello, P; Volpi, D; Roussel, P; Vulpetti, A; Brasca, MG	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307506&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45139991	104161867		CHEMBL599428				ZINC45373710	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50538044	CN1CCN(Cc2ccc(o2)-c2cccc(C#C)c2Cc2ccc3CC=Cc3c2C)CC1	InChI=1S/C29H30N2O/c1-4-22-7-5-10-27(28(22)19-24-12-11-23-8-6-9-26(23)21(24)2)29-14-13-25(32-29)20-31-17-15-30(3)16-18-31/h1,5-7,9-14H,8,15-20H2,2-3H3	OLTHFAIHFDAJGG-UHFFFAOYSA-N	50301686	1-((5-(3-ethynyl-2-((4-methyl-1H-inden-5-yl)methyl)phenyl)furan-2-yl)methyl)-4-methylpiperazine::CHEMBL570865	MAP kinase-activated protein kinase 2	Homo sapiens		>5000							ChEMBL	10.1016/j.bmcl.2009.07.109	10.7270/Q2V69JPF	19682896			Subrath, J; Wang, D; Wu, B; Niu, C; Boschelli, DH; Lee, J; Yang, X; Brennan, A; Chaudhary, D	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50301686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50301686&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45487634	104156047		CHEMBL570865				ZINC53122853	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50539819	CN1CCN(CCOc2cccc(\C=C\c3cncc(C#N)c3Nc3ccc4[nH]ccc4c3C)c2)CC1	InChI=1S/C30H32N6O/c1-22-27-10-11-33-29(27)9-8-28(22)34-30-24(20-32-21-25(30)19-31)7-6-23-4-3-5-26(18-23)37-17-16-36-14-12-35(2)13-15-36/h3-11,18,20-21,33H,12-17H2,1-2H3,(H,32,34)/b7-6+	TUKOILYAIRACKC-VOTSOKGWSA-N	50302507	4-(4-methyl-1H-indol-5-ylamino)-5-(3-(2-(4-methylpiperazin-1-yl)ethoxy)styryl)nicotinonitrile::CHEMBL567124	MAP kinase-activated protein kinase 2	Homo sapiens		>8000							ChEMBL	10.1016/j.bmcl.2009.08.086	10.7270/Q2ZS2WKC	19762237			Niu, C; Boschelli, DH; Tumey, LN; Bhagirath, N; Subrath, J; Shim, J; Wang, Y; Wu, B; Eid, C; Lee, J; Yang, X; Brennan, A; Chaudhary, D	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302507&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45485083	104156868		CHEMBL567124				ZINC45244917	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50551679	CNC(=O)c1nn(C)c-2c1CCc1cnc(NC3CCN(CC3)C(=O)C3CCN(CC3)S(C)(=O)=O)nc-21	InChI=1S/C24H34N8O4S/c1-25-22(33)20-18-5-4-16-14-26-24(28-19(16)21(18)30(2)29-20)27-17-8-10-31(11-9-17)23(34)15-6-12-32(13-7-15)37(3,35)36/h14-15,17H,4-13H2,1-3H3,(H,25,33)(H,26,27,28)	KOLSEKSFVMGHDV-UHFFFAOYSA-N	50307507	CHEMBL597754::N-1-Dimethyl-8-{[1-(methylsulfonyl)piperidin-4-yl]amino}-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm901710h	10.7270/Q2N879W9	20141146			Traquandi, G; Ciomei, M; Ballinari, D; Casale, E; Colombo, N; Croci, V; Fiorentini, F; Isacchi, A; Longo, A; Mercurio, C; Panzeri, A; Pastori, W; Pevarello, P; Volpi, D; Roussel, P; Vulpetti, A; Brasca, MG	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307507&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46233287	104161868		CHEMBL597754				ZINC45356449	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50568386	Cc1ccc(cc1-c1cc2cnn(-c3ccc(F)cc3F)c2n(C)c1=O)C(=O)NC1CC1	InChI=1S/C24H20F2N4O2/c1-13-3-4-14(22(31)28-17-6-7-17)9-18(13)19-10-15-12-27-30(23(15)29(2)24(19)32)21-8-5-16(25)11-20(21)26/h3-5,8-12,17H,6-7H2,1-2H3,(H,28,31)	XQRUWZMHPKNIDA-UHFFFAOYSA-N	50314780	CHEMBL1091199::N-Cyclopropyl-3-(1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-4-methylbenzamide::N-cyclopropyl-3-[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl]-4-methylbenzamide	MAP kinase-activated protein kinase 2	Homo sapiens		 5.7							ChEMBL	10.1021/jm100095x	10.7270/Q2FX79MD	20218619			Pettus, LH; Wurz, RP; Xu, S; Herberich, B; Henkle, B; Liu, Q; McBride, HJ; Mu, S; Plant, MH; Saris, CJ; Sherman, L; Wong, LM; Chmait, S; Lee, MR; Mohr, C; Hsieh, F; Tasker, AS	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314780&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	LHJ	3LHJ	25118220	104149141		CHEMBL1091199				ZINC43200944	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50568387	Cc1ccc(cc1-c1cc2cnn(-c3c(F)cccc3F)c2n(C)c1=O)C(=O)NC1CC1	InChI=1S/C24H20F2N4O2/c1-13-6-7-14(22(31)28-16-8-9-16)10-17(13)18-11-15-12-27-30(23(15)29(2)24(18)32)21-19(25)4-3-5-20(21)26/h3-7,10-12,16H,8-9H2,1-2H3,(H,28,31)	BTFCCPKDGZFGPR-UHFFFAOYSA-N	50314776	CHEMBL1089865::N-Cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)-4-methylbenzamide	MAP kinase-activated protein kinase 2	Homo sapiens		 4.3							ChEMBL	10.1021/jm100095x	10.7270/Q2FX79MD	20218619			Pettus, LH; Wurz, RP; Xu, S; Herberich, B; Henkle, B; Liu, Q; McBride, HJ; Mu, S; Plant, MH; Saris, CJ; Sherman, L; Wong, LM; Chmait, S; Lee, MR; Mohr, C; Hsieh, F; Tasker, AS	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314776&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25052767	104149137		CHEMBL1089865				ZINC43200943	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50568388	Cn1c2n(ncc2cc(-c2cc(ccc2Cl)C(=O)NC2CC2)c1=O)-c1c(F)cccc1F	InChI=1S/C23H17ClF2N4O2/c1-29-22-13(11-27-30(22)20-18(25)3-2-4-19(20)26)10-16(23(29)32)15-9-12(5-8-17(15)24)21(31)28-14-6-7-14/h2-5,8-11,14H,6-7H2,1H3,(H,28,31)	SBVVPLRDGQGTMO-UHFFFAOYSA-N	50314784	4-Chloro-N-cyclopropyl-3-(1-(2,6-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1H-pyrazolo[3,4-b]pyridin-5-yl)benzamide::CHEMBL1091928	MAP kinase-activated protein kinase 2	Homo sapiens		 7							ChEMBL	10.1021/jm100095x	10.7270/Q2FX79MD	20218619			Pettus, LH; Wurz, RP; Xu, S; Herberich, B; Henkle, B; Liu, Q; McBride, HJ; Mu, S; Plant, MH; Saris, CJ; Sherman, L; Wong, LM; Chmait, S; Lee, MR; Mohr, C; Hsieh, F; Tasker, AS	Amgen Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314784&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25119291	104149145		CHEMBL1091928				ZINC43200945	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50561605	CN1CCN(CC1)S(=O)(=O)c1cccc(\C=C\c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)c1	InChI=1S/C28H28N6O2S/c1-20-25-10-11-31-27(25)9-8-26(20)32-28-22(18-30-19-23(28)17-29)7-6-21-4-3-5-24(16-21)37(35,36)34-14-12-33(2)13-15-34/h3-11,16,18-19,31H,12-15H2,1-2H3,(H,30,32)/b7-6+	GMQQMSKNSNVPOW-VOTSOKGWSA-N	50311953	4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile::CHEMBL1080994	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.10.031	10.7270/Q2KD1Z1F	19854645			Shim, J; Eid, C; Lee, J; Liu, E; Chaudhary, D; Boschelli, DH	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311953&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45375865	104146314		CHEMBL1080994				ZINC49032648	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50561606	CN1CCN(CC1)S(=O)(=O)c1cccc(\C=C\c2c(C)ncc(C#N)c2Nc2ccc3[nH]ccc3c2C)c1	InChI=1S/C29H30N6O2S/c1-20-25-11-12-31-28(25)10-9-27(20)33-29-23(18-30)19-32-21(2)26(29)8-7-22-5-4-6-24(17-22)38(36,37)35-15-13-34(3)14-16-35/h4-12,17,19,31H,13-16H2,1-3H3,(H,32,33)/b8-7+	KRMLZRDHQHQPJW-BQYQJAHWSA-N	50311954	6-methyl-4-(4-methyl-1H-indol-5-ylamino)-5-(3-(4-methylpiperazin-1-ylsulfonyl)styryl)nicotinonitrile::CHEMBL1080995	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.10.031	10.7270/Q2KD1Z1F	19854645			Shim, J; Eid, C; Lee, J; Liu, E; Chaudhary, D; Boschelli, DH	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311954&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45375866	104146315		CHEMBL1080995				ZINC49089321	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50558803	CC(C)=CCC\C(C)=C\C[C@]12C[C@@H](CC=C(C)C)C(C)(C)[C@](C\C=C(/C)CCC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)C1=O)C2=O	InChI=1S/C43H58O6/c1-27(2)13-11-15-30(7)21-23-42-26-33(19-17-29(5)6)41(9,10)43(40(42)49,24-22-31(8)16-12-14-28(3)4)39(48)36(38(42)47)37(46)32-18-20-34(44)35(45)25-32/h13-14,17-18,20-22,25,33,36,44-45H,11-12,15-16,19,23-24,26H2,1-10H3/b30-21+,31-22+/t33-,36?,42+,43-/m1/s1	NEGBRCKFFGMDMF-TWQCNMJASA-N	50310785	CHEMBL1078219::guttiferone O	MAP kinase-activated protein kinase 2	Homo sapiens		 22000							ChEMBL	10.1021/np900246t	10.7270/Q2X0675D	19681589			Carroll, AR; Suraweera, L; King, G; Rali, T; Quinn, RJ	Griffith University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310785&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91937018	104145146		CHEMBL1078219					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50558804	CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	HKSZLNNOFSGOKW-ZGQXJOJZSA-N	50059889	(staurosporine)3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::12-[3-methoxy-2,6-dimethyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::12-[3-methoxy-6-methyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::15,16-dimethoxy-15-methyl-17-methylamino-(15S)-4,14,20-triazaheptacyclo[12.12.2.02,6.07,28.08,13.020,27.021,26]octacosa-1(27),2(6),7(28),8(13),9,11,21(26),22,24-nonaen-3-one::2-Amino-4-(2-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one(Staurosporine)::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-::AM-2282::CHEMBL162::Indolocarbazole nitrogen derivative::Isoindolinone Urea derivative::staurosporin	MAP kinase-activated protein kinase 2	Homo sapiens		 150							ChEMBL	10.1021/np900246t	10.7270/Q2X0675D	19681589			Carroll, AR; Suraweera, L; King, G; Rali, T; Quinn, RJ	Griffith University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44299148	103955664		CHEMBL162			C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50558805	CC(C)=CCC\C(C)=C\C[C@]12C[C@@H](CC=C(C)C)[C@](C)(CCC=C(C)C)[C@](CC=C(C)C)(C(=O)C(C(=O)c3ccc(O)c(O)c3)C1=O)C2=O	InChI=1S/C43H58O6/c1-27(2)13-11-15-31(9)21-23-42-26-33(18-16-29(5)6)41(10,22-12-14-28(3)4)43(40(42)49,24-20-30(7)8)39(48)36(38(42)47)37(46)32-17-19-34(44)35(45)25-32/h13-14,16-17,19-21,25,33,36,44-45H,11-12,15,18,22-24,26H2,1-10H3/b31-21+/t33-,36?,41+,42+,43-/m1/s1	VXBWNOKLYLOZDB-VGHCTATHSA-N	50310786	CHEMBL1078220::guttiferone P	MAP kinase-activated protein kinase 2	Homo sapiens		 22000							ChEMBL	10.1021/np900246t	10.7270/Q2X0675D	19681589			Carroll, AR; Suraweera, L; King, G; Rali, T; Quinn, RJ	Griffith University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310786&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91937019	104145147		CHEMBL1078220					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50561667	CN1C[C@@H]2C[C@H]1CN2c1ccc(cc1)-c1ccnc2c(c(nn12)-c1ccncc1)-c1cccc(O)c1	InChI=1S/C29H26N6O/c1-33-17-24-16-23(33)18-34(24)22-7-5-19(6-8-22)26-11-14-31-29-27(21-3-2-4-25(36)15-21)28(32-35(26)29)20-9-12-30-13-10-20/h2-15,23-24,36H,16-18H2,1H3/t23-,24-/m0/s1	MZPDPRITYJNRSG-ZEQRLZLVSA-N	50311985	3-(7-(4-((1S,4S)-5-methyl-2,5-diazabicyclo[2.2.1]heptan-2-yl)phenyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-3-yl)phenol::CHEMBL1087650	MAP kinase-activated protein kinase 2	Homo sapiens		 17100							ChEMBL	10.1016/j.bmcl.2009.10.030	10.7270/Q29Z9510	19854649			Wang, X; Berger, DM; Salaski, EJ; Torres, N; Hu, Y; Levin, JI; Powell, D; Wojciechowicz, D; Collins, K; Frommer, E	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50311985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50311985&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46880136	104146346		CHEMBL1087650				ZINC49112081	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50567308	Cn1cc(\C=C2/Oc3cccc(O)c3C2=O)c2c(ccnc12)-c1ccc(cc1)C(=O)NCCO	InChI=1S/C26H21N3O5/c1-29-14-17(13-21-24(32)23-19(31)3-2-4-20(23)34-21)22-18(9-10-27-25(22)29)15-5-7-16(8-6-15)26(33)28-11-12-30/h2-10,13-14,30-31H,11-12H2,1H3,(H,28,33)/b21-13-	YDELNSXADYPQGS-BKUYFWCQSA-N	50314344	4-(3-((4-hydroxy-3-oxobenzofuran-2(3H)-ylidene)methyl)-1-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl)-N-(2-hydroxyethyl)benzamide::CHEMBL1092754	MAP kinase-activated protein kinase 2	Homo sapiens		 6.5							ChEMBL	10.1016/j.bmcl.2010.01.135	10.7270/Q2PK0G82	20188552			Tsou, HR; MacEwan, G; Birnberg, G; Grosu, G; Bursavich, MG; Bard, J; Brooijmans, N; Toral-Barza, L; Hollander, I; Mansour, TS; Ayral-Kaloustian, S; Yu, K	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314344&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44541014	104148705		CHEMBL1092754			C04080	ZINC49072078	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50576475	COc1ccc(cc1Nc1ncc2CCc3c(nn(C)c3-c2n1)C(N)=O)N1CCN(C)CC1	InChI=1S/C22H19F3N4O4/c1-12-16(13(2)33-28-12)10-29-17-5-4-15(7-18(17)32-11-20(29)30)21(31)27-9-14-3-6-19(26-8-14)22(23,24)25/h3-8H,9-11H2,1-2H3,(H,27,31)	IZHDJXVLMSZONH-UHFFFAOYSA-N	41575	CHEMBL1094408::US8614220, A85B1C1Z	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm901713n	10.7270/Q2RF5V5D	20397705			Beria, I; Ballinari, D; Bertrand, JA; Borghi, D; Bossi, RT; Brasca, MG; Cappella, P; Caruso, M; Ceccarelli, W; Ciavolella, A; Cristiani, C; Croci, V; De Ponti, A; Fachin, G; Ferguson, RD; Lansen, J; Moll, JK; Pesenti, E; Posteri, H; Perego, R; Rocchetti, M; Storici, P; Volpi, D; Valsasina, B	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=41575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=41575&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	071	3KB7	24993189	251974447		CHEMBL1094408				ZINC70725351	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50561820	CN(C)Cc1ccc(cc1)-c1cnn2c(ccnc12)-c1cccc(NC(=O)c2cccc(c2)C(F)(F)F)c1	InChI=1S/C29H24F3N5O/c1-36(2)18-19-9-11-20(12-10-19)25-17-34-37-26(13-14-33-27(25)37)21-5-4-8-24(16-21)35-28(38)22-6-3-7-23(15-22)29(30,31)32/h3-17H,18H2,1-2H3,(H,35,38)	AIWJVLQNYNCDSL-UHFFFAOYSA-N	50312057	CHEMBL1087397::N-(3-(3-(4-((dimethylamino)methyl)phenyl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide::N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	MAP kinase-activated protein kinase 2	Homo sapiens		>2000							ChEMBL	10.1016/j.bmcl.2009.10.049	10.7270/Q2SX6DC7	19864136			Berger, DM; Torres, N; Dutia, M; Powell, D; Ciszewski, G; Gopalsamy, A; Levin, JI; Kim, KH; Xu, W; Wilhelm, J; Hu, Y; Collins, K; Feldberg, L; Kim, S; Frommer, E; Wojciechowicz, D; Mallon, R	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50312057	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50312057&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	831	3II5	24884503	104146418		CHEMBL1087397				ZINC44669088	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557882	CS(=O)(=O)Nc1cccc(c1)-c1cccc(c1)-n1cc(c(N)n1)-c1ccc2C(=O)NCCc2c1	InChI=1S/C25H23N5O3S/c1-34(32,33)29-20-6-2-4-16(13-20)17-5-3-7-21(14-17)30-15-23(24(26)28-30)18-8-9-22-19(12-18)10-11-27-25(22)31/h2-9,12-15,29H,10-11H2,1H3,(H2,26,28)(H,27,31)	HZUITUDYFLHNAZ-UHFFFAOYSA-N	50310341	CHEMBL605125::N-(3'-(3-amino-4-(1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl)-1H-pyrazol-1-yl)biphenyl-3-yl)methanesulfonamide	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310341	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310341&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231583	104144702		CHEMBL605125				ZINC45387609	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557883	Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2nc[nH]c2c1	InChI=1S/C25H20N6O/c26-24-21(17-4-6-20-18(10-17)8-9-27-25(20)32)13-31(30-24)19-3-1-2-15(11-19)16-5-7-22-23(12-16)29-14-28-22/h1-7,10-14H,8-9H2,(H2,26,30)(H,27,32)(H,28,29)	YLTMVGRORXEDOS-UHFFFAOYSA-N	50310342	6-(1-(3-(1H-benzo[d]imidazol-6-yl)phenyl)-3-amino-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL597640	MAP kinase-activated protein kinase 2	Homo sapiens		 82							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310342	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310342&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231584	104144703		CHEMBL597640				ZINC45365000	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557884	Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2cc[nH]c2c1	InChI=1S/C26H21N5O/c27-25-23(19-6-7-22-20(12-19)9-11-29-26(22)32)15-31(30-25)21-3-1-2-17(13-21)18-5-4-16-8-10-28-24(16)14-18/h1-8,10,12-15,28H,9,11H2,(H2,27,30)(H,29,32)	ZTKOUSVWVUFWQC-UHFFFAOYSA-N	50310343	6-(1-(3-(1H-indol-6-yl)phenyl)-3-amino-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::6-{3-amino-1-[3-(1H-indol-6-yl)phenyl]-1H-pyrazol-4-yl}-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL597839	MAP kinase-activated protein kinase 2	Homo sapiens		 61							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310343	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310343&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	LX9	3KGA	44593854	104144704		CHEMBL597839				ZINC44460344	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557885	Cn1ccc2ccc(cc12)-c1cccc(c1)-n1cc(c(N)n1)-c1ccc2C(=O)NCCc2c1	InChI=1S/C27H23N5O/c1-31-12-10-17-5-6-19(15-25(17)31)18-3-2-4-22(14-18)32-16-24(26(28)30-32)20-7-8-23-21(13-20)9-11-29-27(23)33/h2-8,10,12-16H,9,11H2,1H3,(H2,28,30)(H,29,33)	BMZVUCHNAOGFOV-UHFFFAOYSA-N	50310344	6-(3-amino-1-(3-(1-methyl-1H-indol-6-yl)phenyl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL604510	MAP kinase-activated protein kinase 2	Homo sapiens		 290							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310344&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231585	104144705		CHEMBL604510				ZINC45387548	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557886	Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1ccc2CC(=O)Nc2c1	InChI=1S/C26H21N5O2/c27-25-22(17-6-7-21-18(10-17)8-9-28-26(21)33)14-31(30-25)20-3-1-2-15(11-20)16-4-5-19-13-24(32)29-23(19)12-16/h1-7,10-12,14H,8-9,13H2,(H2,27,30)(H,28,33)(H,29,32)	RLDMHCIIQHSPMH-UHFFFAOYSA-N	50310345	6-(3-amino-1-(3-(2-oxoindolin-6-yl)phenyl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL598324	MAP kinase-activated protein kinase 2	Homo sapiens		 220							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310345	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310345&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231638	104144706		CHEMBL598324				ZINC45365674	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557891	COc1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1	InChI=1S/C18H14N4O2/c1-24-13-4-2-11(3-5-13)15-8-12(6-7-19-15)16-9-14-17(22-16)20-10-21-18(14)23/h2-10H,1H3,(H2,20,21,22,23)	SMKRVAGTVDEXFZ-UHFFFAOYSA-N	30311	Pyrrolo-pyrimidone, 4	MAP kinase-activated protein kinase 2	Homo sapiens		 540							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30311&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44143569	85148071						ZINC40860547	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557892	COc1ccc(cc1)-n1cc(cn1)-c1ccc(cc1)C(N)=O	InChI=1S/C17H15N3O2/c1-22-16-8-6-15(7-9-16)20-11-14(10-19-20)12-2-4-13(5-3-12)17(18)21/h2-11H,1H3,(H2,18,21)	FWOOTQWQKQHEHE-UHFFFAOYSA-N	50310346	4-(1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzamide::CHEMBL598506	MAP kinase-activated protein kinase 2	Homo sapiens		 22600							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310346	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310346&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231423	104144707		CHEMBL598506				ZINC45357505	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557893	COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc(cc1)C(N)=O	InChI=1S/C17H16N4O2/c1-23-14-8-6-13(7-9-14)21-10-15(16(18)20-21)11-2-4-12(5-3-11)17(19)22/h2-10H,1H3,(H2,18,20)(H2,19,22)	RASOBZOYDVIHOU-UHFFFAOYSA-N	50310347	4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzamide::CHEMBL598237	MAP kinase-activated protein kinase 2	Homo sapiens		 2000							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310347	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310347&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231473	104144708		CHEMBL598237				ZINC45355308	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557894	COc1ccc(cc1)-n1ncc(c1N)-c1ccc(cc1)C(N)=O	InChI=1S/C17H16N4O2/c1-23-14-8-6-13(7-9-14)21-16(18)15(10-20-21)11-2-4-12(5-3-11)17(19)22/h2-10H,18H2,1H3,(H2,19,22)	DLJOTMUYQOUVAT-UHFFFAOYSA-N	50310348	4-(5-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzamide::CHEMBL598449	MAP kinase-activated protein kinase 2	Homo sapiens		 22500							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310348	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310348&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			15366651	104144709		CHEMBL598449				ZINC45357010	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557895	COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc(cc1)C#N	InChI=1S/C17H14N4O/c1-22-15-8-6-14(7-9-15)21-11-16(17(19)20-21)13-4-2-12(10-18)3-5-13/h2-9,11H,1H3,(H2,19,20)	RVPDZRDQXBPPGA-UHFFFAOYSA-N	50310349	4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzonitrile::CHEMBL597628	MAP kinase-activated protein kinase 2	Homo sapiens		 31200							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310349	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310349&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231474	104144710		CHEMBL597628				ZINC45358264	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557896	COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc(cc1)S(N)(=O)=O	InChI=1S/C16H16N4O3S/c1-23-13-6-4-12(5-7-13)20-10-15(16(17)19-20)11-2-8-14(9-3-11)24(18,21)22/h2-10H,1H3,(H2,17,19)(H2,18,21,22)	ZEDCEJVRUQKGLP-UHFFFAOYSA-N	50310350	4-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)benzenesulfonamide::CHEMBL597629	MAP kinase-activated protein kinase 2	Homo sapiens		 15400							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310350	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310350&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231475	104144711		CHEMBL597629				ZINC45358266	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557897	COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2C(=O)NCc2c1	InChI=1S/C18H16N4O2/c1-24-14-5-3-13(4-6-14)22-10-16(17(19)21-22)11-2-7-15-12(8-11)9-20-18(15)23/h2-8,10H,9H2,1H3,(H2,19,21)(H,20,23)	WMSFWSYGCTUSCV-UHFFFAOYSA-N	50310351	5-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)isoindolin-1-one::CHEMBL590491	MAP kinase-activated protein kinase 2	Homo sapiens		 6000							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310351	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310351&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231476	104144712		CHEMBL590491				ZINC45336917	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557898	COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2CCNC(=O)c2c1	InChI=1S/C19H18N4O2/c1-25-15-6-4-14(5-7-15)23-11-17(18(20)22-23)13-3-2-12-8-9-21-19(24)16(12)10-13/h2-7,10-11H,8-9H2,1H3,(H2,20,22)(H,21,24)	ZBIFKWQZJMJWRU-UHFFFAOYSA-N	50310352	7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL610780	MAP kinase-activated protein kinase 2	Homo sapiens		 84							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310352	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310352&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231477	104144713		CHEMBL610780				ZINC45393488	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557899	COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2CCCNC(=O)c2c1	InChI=1S/C20H20N4O2/c1-26-16-8-6-15(7-9-16)24-12-18(19(21)23-24)14-5-4-13-3-2-10-22-20(25)17(13)11-14/h4-9,11-12H,2-3,10H2,1H3,(H2,21,23)(H,22,25)	IJKJOSCNBDISNN-UHFFFAOYSA-N	50310353	8-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-2,3,4,5-tetrahydro-1H-benzo[c]azepin-1-one::CHEMBL599478	MAP kinase-activated protein kinase 2	Homo sapiens		 1100							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310353	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310353&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231531	104144714		CHEMBL599478				ZINC45372800	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557900	COc1ccc(cc1)-n1cc(c(N)n1)-c1ccc2OCCNC(=O)c2c1	InChI=1S/C19H18N4O3/c1-25-14-5-3-13(4-6-14)23-11-16(18(20)22-23)12-2-7-17-15(10-12)19(24)21-8-9-26-17/h2-7,10-11H,8-9H2,1H3,(H2,20,22)(H,21,24)	VMGQJHNQXDZODH-UHFFFAOYSA-N	50310354	7-(3-amino-1-(4-methoxyphenyl)-1H-pyrazol-4-yl)-3,4-dihydrobenzo[f][1,4]oxazepin-5(2H)-one::CHEMBL599479	MAP kinase-activated protein kinase 2	Homo sapiens		 350							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310354	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310354&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231532	104144715		CHEMBL599479				ZINC45373293	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557901	Nc1nn(cc1-c1ccc2C(=O)NCCc2c1)-c1cccc(c1)-c1cccc(O)c1	InChI=1S/C24H20N4O2/c25-23-22(17-7-8-21-18(11-17)9-10-26-24(21)30)14-28(27-23)19-5-1-3-15(12-19)16-4-2-6-20(29)13-16/h1-8,11-14,29H,9-10H2,(H2,25,27)(H,26,30)	FRKWUYUWMYUILV-UHFFFAOYSA-N	50310355	6-(3-amino-1-(3'-hydroxybiphenyl-3-yl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL603694	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310355	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310355&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231533	104144716		CHEMBL603694				ZINC45391520	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50557902	COc1cccc(c1)-c1cccc(c1)-n1cc(c(N)n1)-c1ccc2C(=O)NCCc2c1	InChI=1S/C25H22N4O2/c1-31-21-7-3-5-17(14-21)16-4-2-6-20(13-16)29-15-23(24(26)28-29)18-8-9-22-19(12-18)10-11-27-25(22)30/h2-9,12-15H,10-11H2,1H3,(H2,26,28)(H,27,30)	AEWVQURONHNXMU-UHFFFAOYSA-N	50310356	6-(3-amino-1-(3'-methoxybiphenyl-3-yl)-1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-1(2H)-one::CHEMBL599682	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2009.10.138	10.7270/Q2MP53C5	20060294			Velcicky, J; Feifel, R; Hawtin, S; Heng, R; Huppertz, C; Koch, G; Kroemer, M; Moebitz, H; Revesz, L; Scheufler, C; Schlapbach, A	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50310356	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50310356&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46231534	104144717		CHEMBL599682				ZINC45374164	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50572000	CC(C)(C)OC(=O)N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc(N)cc1)N1CCOCC1	InChI=1S/C25H33N7O3/c1-25(2,3)35-24(33)31-10-8-19(9-11-31)32-23-20(16-27-32)22(30-12-14-34-15-13-30)28-21(29-23)17-4-6-18(26)7-5-17/h4-7,16,19H,8-15,26H2,1-3H3	OHKRUKRKVNWNNT-UHFFFAOYSA-N	50316253	CHEMBL1095627::tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1021/jm9013828	10.7270/Q28W3DGF	19894727			Verheijen, JC; Richard, DJ; Curran, K; Kaplan, J; Lefever, M; Nowak, P; Malwitz, DJ; Brooijmans, N; Toral-Barza, L; Zhang, WG; Lucas, J; Hollander, I; Ayral-Kaloustian, S; Mansour, TS; Yu, K; Zask, A	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316253	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316253&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44605037	104150614		CHEMBL1095627				ZINC49783651	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50572019	COC(=O)N1CCC(CC1)n1ncc2c(nc(nc12)-c1ccc(N)cc1)N1CCOCC1	InChI=1S/C22H27N7O3/c1-31-22(30)28-8-6-17(7-9-28)29-21-18(14-24-29)20(27-10-12-32-13-11-27)25-19(26-21)15-2-4-16(23)5-3-15/h2-5,14,17H,6-13,23H2,1H3	OFIHBQUKIUHAHV-UHFFFAOYSA-N	50316252	CHEMBL1095626::methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1021/jm9013828	10.7270/Q28W3DGF	19894727			Verheijen, JC; Richard, DJ; Curran, K; Kaplan, J; Lefever, M; Nowak, P; Malwitz, DJ; Brooijmans, N; Toral-Barza, L; Zhang, WG; Lucas, J; Hollander, I; Ayral-Kaloustian, S; Mansour, TS; Yu, K; Zask, A	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50316252	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50316252&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44605035	104150613		CHEMBL1095626				ZINC49783650	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50575513	Fc1ccc(NC(=O)c2cccnc2Nc2ccc(Oc3ccnc4[nH]ccc34)c(F)c2)c(F)c1	InChI=1S/C25H16F3N5O2/c26-14-3-5-20(18(27)12-14)33-25(34)17-2-1-9-29-24(17)32-15-4-6-22(19(28)13-15)35-21-8-11-31-23-16(21)7-10-30-23/h1-13H,(H,29,32)(H,30,31)(H,33,34)	ZXWBEPIEIMDBRM-UHFFFAOYSA-N	50317750	2-(4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide::CHEMBL1095873	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2010.01.042	10.7270/Q2PN95TM	20382527			Williams, DK; Chen, XT; Tarby, C; Kaltenbach, R; Cai, ZW; Tokarski, JS; An, Y; Sack, JS; Wautlet, B; Gullo-Brown, J; Henley, BJ; Jeyaseelan, R; Kellar, K; Manne, V; Trainor, GL; Lombardo, LJ; Fargnoli, J; Borzilleri, RM	Bristol-Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50317750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50317750&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16223008	104152111		CHEMBL1095873				ZINC49088116	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50566490	FC(F)(F)c1cccc(c1)C(=O)Nc1cccc(c1)-c1ccnc2cc(nn12)-c1ccncc1	InChI=1S/C25H16F3N5O/c26-25(27,28)19-5-1-4-18(13-19)24(34)31-20-6-2-3-17(14-20)22-9-12-30-23-15-21(32-33(22)23)16-7-10-29-11-8-16/h1-15H,(H,31,34)	LCMNWMABPDVIPG-UHFFFAOYSA-N	50314051	CHEMBL1089082::N-(3-(2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)phenyl)-3-(trifluoromethyl)benzamide	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.10.074	10.7270/Q2C829F3	19884006			Gopalsamy, A; Ciszewski, G; Shi, M; Berger, D; Hu, Y; Lee, F; Feldberg, L; Frommer, E; Kim, S; Collins, K; Wojciechowicz, D; Mallon, R	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50314051	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50314051&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24822704	104148412		CHEMBL1089082				ZINC49068339	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50595489	CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(OCCN4CCOCC4)ccc32)no1	InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)	CVWXJKQAOSCOAB-UHFFFAOYSA-N	50300690	1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea::AC 010220::AC 220::AC-220::AC010220::AC220::ASP-2689::CHEMBL576982::N-(5-tert-Butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea::Quizartinib::Quizartinib (AC220)::US10266535, Compound AC220::US11542261, Compound quizartinib::US9216997, Quizartinib (positive compound)	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1182/blood-2009-05-222034	10.7270/Q2PN95V2	19654408			Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300690&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P30	4XUF,4RT7	24889392	104155051		CHEMBL576982		5658		ZINC43204002	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50601891	O=C(N[C@H](CN1CCCC1)c1ccccc1)c1cc2n[nH]c(NC(=O)c3ccc(cc3)N3CCOCC3)c2s1	InChI=1S/C29H32N6O3S/c36-28(21-8-10-22(11-9-21)35-14-16-38-17-15-35)31-27-26-23(32-33-27)18-25(39-26)29(37)30-24(19-34-12-4-5-13-34)20-6-2-1-3-7-20/h1-3,6-11,18,24H,4-5,12-17,19H2,(H,30,37)(H2,31,32,33,36)/t24-/m1/s1	ORWIYCURPDKSBI-XMMPIXPASA-N	50327912	3-(4-Morpholin-4-yl-benzoylamino)-1H-thieno[3,2-c]pyrazole-5-carboxylic acid((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-amide::CHEMBL1258913	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2010.07.048	10.7270/Q2Q240GM	20817473			Bindi, S; Fancelli, D; Alli, C; Berta, D; Bertrand, JA; Cameron, AD; Cappella, P; Carpinelli, P; Cervi, G; Croci, V; D'Anello, M; Forte, B; Giorgini, ML; Marsiglio, A; Moll, J; Pesenti, E; Pittala, V; Pulici, M; Riccardi-Sirtori, F; Roletto, F; Soncini, C; Storici, P; Varasi, M; Volpi, D; Zugnoni, P; Vianello, P	Nerviano Medical Sciences Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50327912	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50327912&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11847343	123107027		CHEMBL1258913				ZINC43132736	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50595892	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1	InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	MLDQJTXFUGDVEO-UHFFFAOYSA-N	16673	4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide::4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-picolinamide;tosylic acid::BAY 43-9006::BAY 439006::BAY439006::CHEMBL1336::Hit compound, 8::Nexavar::Sorafenib::Sorafenib, 4::US10183928, Sorafenib::US10202365, Compound Sorafenib::US10227329, Compound Sorafenib::US10584114, Compound Sorafenib::US10774070, Compound Sorafenib::US10980809, Example Sorafenib::US11279688, Compound Sorafenib::US11505527, Compound Sorafenib::US9029401, Sorafenib::US9469639, Sorafenib::US9902709, Comparative example 1::Xarelto::cid_216239	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1182/blood-2009-05-222034	10.7270/Q2PN95V2	19654408			Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16673&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	BAX	3GCS,4ASD,3WZE,5HI2,3HEG,1UWH,1UWJ,3RGF	216239	46516901	50924	CHEMBL1336	DB00398	5711		ZINC01493878	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50594388	CC(=O)c1c(O)c(C)c(O)c(Cc2c(O)c3C=CC(C)(C)Oc3c(C(=O)C=Cc3ccccc3)c2O)c1O	InChI=1S/C30H28O8/c1-15-24(33)19(27(36)22(16(2)31)25(15)34)14-20-26(35)18-12-13-30(3,4)38-29(18)23(28(20)37)21(32)11-10-17-8-6-5-7-9-17/h5-13,33-37H,14H2,1-4H3	DEZFNHCVIZBHBI-UHFFFAOYSA-N	50126829	(E)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one::1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one::1-[6-(3-Acetyl-2,4,6-trihydroxy-5-methyl-benzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl]-3-phenyl-propenone::CHEMBL34241::R5648 (Rottlerin)::ROTTLERIN	MAP kinase-activated protein kinase 2	Homo sapiens		 5400							ChEMBL	10.1042/0264-6021:3510095	10.7270/Q24T6JKN	10998351			Davies, SP; Reddy, H; Caivano, M; Cohen, P	University of Dundee	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50126829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50126829&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			5281847	104018897	8899	CHEMBL34241		2611		ZINC03874886	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50596257	CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c4[C@H](O)NC(=O)c4c4c5ccccc5n2c4c13)N(C)C(=O)c1ccccc1	InChI=1S/C35H30N4O5/c1-35-31(43-3)23(37(2)34(42)18-11-5-4-6-12-18)17-24(44-35)38-21-15-9-7-13-19(21)25-27-28(33(41)36-32(27)40)26-20-14-8-10-16-22(20)39(35)30(26)29(25)38/h4-16,23-24,31,33,41H,17H2,1-3H3,(H,36,40)/t23-,24-,31-,33+,35+/m1/s1	ZZSBPGIGIUFJRA-AKIDMACVSA-N	50326054	CHEMBL1240703	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1182/blood-2009-05-222034	10.7270/Q2PN95V2	19654408			Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50326054	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50326054&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			52945601	123105169		CHEMBL1240703					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50586523	CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	HKSZLNNOFSGOKW-ZGQXJOJZSA-N	50059889	(staurosporine)3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::12-[3-methoxy-2,6-dimethyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::12-[3-methoxy-6-methyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::15,16-dimethoxy-15-methyl-17-methylamino-(15S)-4,14,20-triazaheptacyclo[12.12.2.02,6.07,28.08,13.020,27.021,26]octacosa-1(27),2(6),7(28),8(13),9,11,21(26),22,24-nonaen-3-one::2-Amino-4-(2-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one(Staurosporine)::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-::AM-2282::CHEMBL162::Indolocarbazole nitrogen derivative::Isoindolinone Urea derivative::staurosporin	MAP kinase-activated protein kinase 2	Homo sapiens		 36.25							ChEMBL	10.1016/j.ejmech.2010.04.026	10.7270/Q2TH8MWC	20472330			Ibrahim, N; Mouawad, L; Legraverend, M	Institut Curie	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44299148	103955664		CHEMBL162			C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588577	N(c1ccccc1)c1ccnc2ccc(cc12)-c1ccccc1	InChI=1S/C21H16N2/c1-3-7-16(8-4-1)17-11-12-20-19(15-17)21(13-14-22-20)23-18-9-5-2-6-10-18/h1-15H,(H,22,23)	TXRKWTYKOAPCCF-UHFFFAOYSA-N	50323614	CHEMBL1209750::N,6-diphenylquinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323614	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323614&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862702	117644935		CHEMBL1209750				ZINC58487391	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588578	OCCc1ccc(Nc2ccnc3ccc(cc23)-c2ccccc2)cc1	InChI=1S/C23H20N2O/c26-15-13-17-6-9-20(10-7-17)25-23-12-14-24-22-11-8-19(16-21(22)23)18-4-2-1-3-5-18/h1-12,14,16,26H,13,15H2,(H,24,25)	JARWZNQSRILQLG-UHFFFAOYSA-N	50323615	2-(4-(6-phenylquinolin-4-ylamino)phenyl)ethanol::CHEMBL1209751	MAP kinase-activated protein kinase 2	Homo sapiens		 22000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323615	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323615&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862703	117644936		CHEMBL1209751				ZINC58487637	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588579	CCc1ccc(Nc2ccnc3ccc(cc23)-c2ccccc2)cc1	InChI=1S/C23H20N2/c1-2-17-8-11-20(12-9-17)25-23-14-15-24-22-13-10-19(16-21(22)23)18-6-4-3-5-7-18/h3-16H,2H2,1H3,(H,24,25)	GYNPHGRXVZWBTC-UHFFFAOYSA-N	50323616	CHEMBL1209752::N-(4-ethylphenyl)-6-phenylquinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 41000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323616	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323616&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862704	117644937		CHEMBL1209752				ZINC58502045	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588580	C1CN(CCO1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccccc2)cc1	InChI=1S/C25H23N3O/c1-2-4-19(5-3-1)20-6-11-24-23(18-20)25(12-13-26-24)27-21-7-9-22(10-8-21)28-14-16-29-17-15-28/h1-13,18H,14-17H2,(H,26,27)	SGFXIGDZMUKKKK-UHFFFAOYSA-N	50323617	CHEMBL1209832::N-(4-morpholinophenyl)-6-phenylquinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 120000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323617&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862778	117644938		CHEMBL1209832				ZINC58502020	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588581	OC(=O)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C22H15ClN2O2/c23-17-6-1-14(2-7-17)16-5-10-20-19(13-16)21(11-12-24-20)25-18-8-3-15(4-9-18)22(26)27/h1-13H,(H,24,25)(H,26,27)	VVRQGWBKWDKSQY-UHFFFAOYSA-N	50323618	4-(6-(4-chlorophenyl)quinolin-4-ylamino)benzoic acid::CHEMBL1209833	MAP kinase-activated protein kinase 2	Homo sapiens		 12000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323618	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323618&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862779	117644939		CHEMBL1209833				ZINC58626622	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588582	Oc1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C21H15ClN2O/c22-16-4-1-14(2-5-16)15-3-10-20-19(13-15)21(11-12-23-20)24-17-6-8-18(25)9-7-17/h1-13,25H,(H,23,24)	CUBGQJGBOQTQER-UHFFFAOYSA-N	50323619	4-(6-(4-chlorophenyl)quinolin-4-ylamino)phenol::CHEMBL1209834	MAP kinase-activated protein kinase 2	Homo sapiens		 23000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323619	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323619&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862780	117644940		CHEMBL1209834				ZINC58502027	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588583	Clc1ccc(cc1)-c1ccc2nccc(Nc3ccc(cc3)N3CCOCC3)c2c1	InChI=1S/C25H22ClN3O/c26-20-4-1-18(2-5-20)19-3-10-24-23(17-19)25(11-12-27-24)28-21-6-8-22(9-7-21)29-13-15-30-16-14-29/h1-12,17H,13-16H2,(H,27,28)	PIFRWBJSCGGTHH-UHFFFAOYSA-N	50323620	6-(4-chlorophenyl)-N-(4-morpholinophenyl)quinolin-4-amine::CHEMBL1209835	MAP kinase-activated protein kinase 2	Homo sapiens		 24000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323620	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323620&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862781	117644941		CHEMBL1209835				ZINC58502164	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588584	OCCc1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C23H19ClN2O/c24-19-6-3-17(4-7-19)18-5-10-22-21(15-18)23(11-13-25-22)26-20-8-1-16(2-9-20)12-14-27/h1-11,13,15,27H,12,14H2,(H,25,26)	AMPFDJPYAXBAGV-UHFFFAOYSA-N	50323621	2-(4-(6-(4-chlorophenyl)quinolin-4-ylamino)phenyl)ethanol::CHEMBL1209836	MAP kinase-activated protein kinase 2	Homo sapiens		 29000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323621&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862782	117644942		CHEMBL1209836				ZINC58502031	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588585	Clc1ccc(cc1)-c1ccc2nccc(Nc3ccc(cc3)C#N)c2c1	InChI=1S/C22H14ClN3/c23-18-6-3-16(4-7-18)17-5-10-21-20(13-17)22(11-12-25-21)26-19-8-1-15(14-24)2-9-19/h1-13H,(H,25,26)	VBCUFNWLUJXTRM-UHFFFAOYSA-N	50323622	4-(6-(4-chlorophenyl)quinolin-4-ylamino)benzonitrile::CHEMBL1208823	MAP kinase-activated protein kinase 2	Homo sapiens		 27000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323622	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323622&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862001	117644943		CHEMBL1208823				ZINC58512403	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588586	CN1CCN(CC1)C(=O)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C27H25ClN4O/c1-31-14-16-32(17-15-31)27(33)20-4-9-23(10-5-20)30-26-12-13-29-25-11-6-21(18-24(25)26)19-2-7-22(28)8-3-19/h2-13,18H,14-17H2,1H3,(H,29,30)	OOVIIDNGMFZNKV-UHFFFAOYSA-N	50323623	(4-(6-(4-chlorophenyl)quinolin-4-ylamino)phenyl)(4-methylpiperazin-1-yl)methanone::CHEMBL1208824	MAP kinase-activated protein kinase 2	Homo sapiens		 15000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323623	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323623&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862002	117644944		CHEMBL1208824				ZINC58520017	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588587	Cc1ccc(cc1)-c1ccc2nccc(Nc3cc(Cl)ccc3O)c2c1	InChI=1S/C22H17ClN2O/c1-14-2-4-15(5-3-14)16-6-8-19-18(12-16)20(10-11-24-19)25-21-13-17(23)7-9-22(21)26/h2-13,26H,1H3,(H,24,25)	PXNPRPSSJLMRRN-UHFFFAOYSA-N	50323624	4-chloro-2-(6-p-tolylquinolin-4-ylamino)phenol::CHEMBL1208825	MAP kinase-activated protein kinase 2	Homo sapiens		 33000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323624	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323624&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862003	117644945		CHEMBL1208825				ZINC58520070	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588588	Cc1ccc(cc1)-c1ccc2nccc(Nc3ccc(O)cc3)c2c1	InChI=1S/C22H18N2O/c1-15-2-4-16(5-3-15)17-6-11-21-20(14-17)22(12-13-23-21)24-18-7-9-19(25)10-8-18/h2-14,25H,1H3,(H,23,24)	NPXHXMOCXQWUJM-UHFFFAOYSA-N	50323625	4-(6-p-tolylquinolin-4-ylamino)phenol::CHEMBL1208826	MAP kinase-activated protein kinase 2	Homo sapiens		 25000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323625	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323625&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862004	117644946		CHEMBL1208826				ZINC58520217	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588589	Cc1ccc(cc1)-c1ccc2nccc(Nc3ccc(cc3)C#N)c2c1	InChI=1S/C23H17N3/c1-16-2-6-18(7-3-16)19-8-11-22-21(14-19)23(12-13-25-22)26-20-9-4-17(15-24)5-10-20/h2-14H,1H3,(H,25,26)	QYAXSXIJHHOIDS-UHFFFAOYSA-N	50323626	4-(6-p-tolylquinolin-4-ylamino)benzonitrile::CHEMBL1208827	MAP kinase-activated protein kinase 2	Homo sapiens		 27000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323626	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323626&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862005	117644947		CHEMBL1208827				ZINC58519939	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588590	Cc1ccc(cc1)-c1ccc2nccc(Nc3cccc(C)c3C)c2c1	InChI=1S/C24H22N2/c1-16-7-9-19(10-8-16)20-11-12-23-21(15-20)24(13-14-25-23)26-22-6-4-5-17(2)18(22)3/h4-15H,1-3H3,(H,25,26)	KZAUGELBXZQFOM-UHFFFAOYSA-N	50323627	CHEMBL1208885::N-(2,3-dimethylphenyl)-6-p-tolylquinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 35000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323627&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862049	117644948		CHEMBL1208885				ZINC58520177	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588591	Oc1ccc(Cl)cc1Nc1ccnc2ccc(cc12)-c1ccccc1	InChI=1S/C21H15ClN2O/c22-16-7-9-21(25)20(13-16)24-19-10-11-23-18-8-6-15(12-17(18)19)14-4-2-1-3-5-14/h1-13,25H,(H,23,24)	BJWMDPZDQJVEFN-UHFFFAOYSA-N	50323628	4-chloro-2-(6-phenylquinolin-4-ylamino)phenol::CHEMBL1208886	MAP kinase-activated protein kinase 2	Homo sapiens		 43000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323628&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862050	117644949		CHEMBL1208886				ZINC58590534	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588592	Fc1cc(Cl)ccc1Nc1ccnc2ccc(cc12)-c1ccc(Cl)cc1	InChI=1S/C21H13Cl2FN2/c22-15-4-1-13(2-5-15)14-3-7-19-17(11-14)20(9-10-25-19)26-21-8-6-16(23)12-18(21)24/h1-12H,(H,25,26)	DBPKEFMIWKBZQK-UHFFFAOYSA-N	50323629	CHEMBL1208887::N-(4-chloro-2-fluorophenyl)-6-(4-chlorophenyl)quinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 121000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323629&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862051	117644950		CHEMBL1208887				ZINC58523653	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588593	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccccc2)cc1	InChI=1S/C26H26N4/c1-29-15-17-30(18-16-29)23-10-8-22(9-11-23)28-26-13-14-27-25-12-7-21(19-24(25)26)20-5-3-2-4-6-20/h2-14,19H,15-18H2,1H3,(H,27,28)	YMBNETKULXIEPR-UHFFFAOYSA-N	50323630	CHEMBL549224::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-phenylquinolin-4-amine::TCMDC-123917	MAP kinase-activated protein kinase 2	Homo sapiens		 5200							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323630	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323630&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			3264448	117644951		CHEMBL549224				ZINC53064461	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588594	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccsc2)cc1	InChI=1S/C24H24N4S/c1-27-11-13-28(14-12-27)21-5-3-20(4-6-21)26-24-8-10-25-23-7-2-18(16-22(23)24)19-9-15-29-17-19/h2-10,15-17H,11-14H2,1H3,(H,25,26)	RDQOKHHIOBETQG-UHFFFAOYSA-N	50323631	CHEMBL1208888::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(thiophen-3-yl)quinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 26000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323631	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323631&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862052	117644952		CHEMBL1208888				ZINC58523492	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588595	CN1CCN(CC1)c1ccc(Nc2ccnc3ccccc23)cc1	InChI=1S/C20H22N4/c1-23-12-14-24(15-13-23)17-8-6-16(7-9-17)22-20-10-11-21-19-5-3-2-4-18(19)20/h2-11H,12-15H2,1H3,(H,21,22)	RXXDJBWYJTWSKV-UHFFFAOYSA-N	50196110	CHEMBL217665::GNF-PF-2857::N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::[4-(4-methylpiperazin-1-yl)phenyl]quinolin-4-ylamine	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50196110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50196110&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			4567175	104077986		CHEMBL217665				ZINC52962019	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588596	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(Br)cc23)cc1	InChI=1S/C20H21BrN4/c1-24-10-12-25(13-11-24)17-5-3-16(4-6-17)23-20-8-9-22-19-7-2-15(21)14-18(19)20/h2-9,14H,10-13H2,1H3,(H,22,23)	CGCYZGLZJSUFMP-UHFFFAOYSA-N	50323632	6-bromo-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1208948	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323632&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862087	117644953		CHEMBL1208948				ZINC58638751	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588597	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2cccs2)cc1	InChI=1S/C24H24N4S/c1-27-12-14-28(15-13-27)20-7-5-19(6-8-20)26-23-10-11-25-22-9-4-18(17-21(22)23)24-3-2-16-29-24/h2-11,16-17H,12-15H2,1H3,(H,25,26)	NYAKXFGVENFYPE-UHFFFAOYSA-N	50323633	CHEMBL1208949::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(thiophen-2-yl)quinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323633&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862088	117644954		CHEMBL1208949				ZINC58520201	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588598	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Br)cc2)cc1	InChI=1S/C26H25BrN4/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-4-20(18-24(25)26)19-2-5-21(27)6-3-19/h2-13,18H,14-17H2,1H3,(H,28,29)	KLDDIZKJFLATAF-UHFFFAOYSA-N	50323634	6-(4-bromophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1208950	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323634&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46927902	117644955		CHEMBL1208950				ZINC58523409	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588599	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C26H25ClN4/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-4-20(18-24(25)26)19-2-5-21(27)6-3-19/h2-13,18H,14-17H2,1H3,(H,28,29)	CQERPSZQVAXWHF-UHFFFAOYSA-N	50323635	6-(4-chlorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1208951	MAP kinase-activated protein kinase 2	Homo sapiens		 600							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11575548	117644956		CHEMBL1208951				ZINC58520190	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588600	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(F)cc2)cc1	InChI=1S/C26H25FN4/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-4-20(18-24(25)26)19-2-5-21(27)6-3-19/h2-13,18H,14-17H2,1H3,(H,28,29)	RZZOZKNFFPMJFF-UHFFFAOYSA-N	50323636	6-(4-fluorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1209008	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323636&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11517184	117644957		CHEMBL1209008				ZINC58534715	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588601	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(cc2)C(O)=O)cc1	InChI=1S/C27H26N4O2/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-6-21(18-24(25)26)19-2-4-20(5-3-19)27(32)33/h2-13,18H,14-17H2,1H3,(H,28,29)(H,32,33)	XIUINWUMVJSAEM-UHFFFAOYSA-N	50323637	4-(4-(4-(4-methylpiperazin-1-yl)phenylamino)quinolin-6-yl)benzoic acid::CHEMBL1209009	MAP kinase-activated protein kinase 2	Homo sapiens		>200000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323637&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862123	117644958		CHEMBL1209009				ZINC58538072	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588602	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2cccc(c2)[N+]([O-])=O)cc1	InChI=1S/C26H25N5O2/c1-29-13-15-30(16-14-29)22-8-6-21(7-9-22)28-26-11-12-27-25-10-5-20(18-24(25)26)19-3-2-4-23(17-19)31(32)33/h2-12,17-18H,13-16H2,1H3,(H,27,28)	XRUMFCRCPBCILD-UHFFFAOYSA-N	50323638	CHEMBL1209010::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(3-nitrophenyl)quinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 9000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323638&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11719115	117644959		CHEMBL1209010				ZINC58538431	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588603	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2cccc(N)c2)cc1	InChI=1S/C26H27N5/c1-30-13-15-31(16-14-30)23-8-6-22(7-9-23)29-26-11-12-28-25-10-5-20(18-24(25)26)19-3-2-4-21(27)17-19/h2-12,17-18H,13-16,27H2,1H3,(H,28,29)	GLUOXTMCSMWSRM-UHFFFAOYSA-N	50323639	6-(3-aminophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1209011	MAP kinase-activated protein kinase 2	Homo sapiens		 14000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323639&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862124	117644960		CHEMBL1209011				ZINC58538191	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588604	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2cccc(c2)C(F)(F)F)cc1	InChI=1S/C27H25F3N4/c1-33-13-15-34(16-14-33)23-8-6-22(7-9-23)32-26-11-12-31-25-10-5-20(18-24(25)26)19-3-2-4-21(17-19)27(28,29)30/h2-12,17-18H,13-16H2,1H3,(H,31,32)	UZEDLEVQHJATDH-UHFFFAOYSA-N	50323640	CHEMBL1209066::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(3-(trifluoromethyl)phenyl)quinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 1500							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323640	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323640&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11525487	117644961		CHEMBL1209066				ZINC58538355	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588605	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2cccc(Cl)c2)cc1	InChI=1S/C26H25ClN4/c1-30-13-15-31(16-14-30)23-8-6-22(7-9-23)29-26-11-12-28-25-10-5-20(18-24(25)26)19-3-2-4-21(27)17-19/h2-12,17-18H,13-16H2,1H3,(H,28,29)	XBVRPTCUVVCGKN-UHFFFAOYSA-N	50323641	6-(3-chlorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1209067	MAP kinase-activated protein kinase 2	Homo sapiens		 2600							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323641&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11495655	117644962		CHEMBL1209067				ZINC58537952	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588606	COc1cccc(c1)-c1ccc2nccc(Nc3ccc(cc3)N3CCN(C)CC3)c2c1	InChI=1S/C27H28N4O/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-27-12-13-28-26-11-6-21(19-25(26)27)20-4-3-5-24(18-20)32-2/h3-13,18-19H,14-17H2,1-2H3,(H,28,29)	MPYSFSAKGUFQCW-UHFFFAOYSA-N	50323642	6-(3-methoxyphenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1209068	MAP kinase-activated protein kinase 2	Homo sapiens		 8000							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323642	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323642&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11654763	117644963		CHEMBL1209068				ZINC58538301	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50595096	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1182/blood-2009-05-222034	10.7270/Q2PN95V2	19654408			Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588607	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(C=O)cc2)cc1	InChI=1S/C27H26N4O/c1-30-14-16-31(17-15-30)24-9-7-23(8-10-24)29-27-12-13-28-26-11-6-22(18-25(26)27)21-4-2-20(19-32)3-5-21/h2-13,18-19H,14-17H2,1H3,(H,28,29)	GHKIAGUJUFVADU-UHFFFAOYSA-N	50323643	4-(4-(4-(4-methylpiperazin-1-yl)phenylamino)quinolin-6-yl)benzaldehyde::CHEMBL1209069	MAP kinase-activated protein kinase 2	Homo sapiens		 1800							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323643	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323643&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49862167	117644964		CHEMBL1209069				ZINC58540753	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588608	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(cc2)C(F)(F)F)cc1	InChI=1S/C27H25F3N4/c1-33-14-16-34(17-15-33)23-9-7-22(8-10-23)32-26-12-13-31-25-11-4-20(18-24(25)26)19-2-5-21(6-3-19)27(28,29)30/h2-13,18H,14-17H2,1H3,(H,31,32)	PWLARPCPJDTUFU-UHFFFAOYSA-N	50323644	CHEMBL1209119::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(4-(trifluoromethyl)phenyl)quinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323644	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323644&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11554437	117644965		CHEMBL1209119				ZINC58538203	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588609	CSc1ccc(cc1)-c1ccc2nccc(Nc3ccc(cc3)N3CCN(C)CC3)c2c1	InChI=1S/C27H28N4S/c1-30-15-17-31(18-16-30)23-8-6-22(7-9-23)29-27-13-14-28-26-12-5-21(19-25(26)27)20-3-10-24(32-2)11-4-20/h3-14,19H,15-18H2,1-2H3,(H,28,29)	WKWSSSBOFOOKQN-UHFFFAOYSA-N	50323645	CHEMBL1209120::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-(4-(methylthio)phenyl)quinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323645	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323645&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11604613	117644966		CHEMBL1209120				ZINC58534742	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588610	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(C)cc2)cc1	InChI=1S/C27H28N4/c1-20-3-5-21(6-4-20)22-7-12-26-25(19-22)27(13-14-28-26)29-23-8-10-24(11-9-23)31-17-15-30(2)16-18-31/h3-14,19H,15-18H2,1-2H3,(H,28,29)	FYMURMGSNGUNKE-UHFFFAOYSA-N	50323646	CHEMBL1209121::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-p-tolylquinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 800							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323646&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11718461	117644967		CHEMBL1209121				ZINC58651241	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588611	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2cccc(C)c2)cc1	InChI=1S/C27H28N4/c1-20-4-3-5-21(18-20)22-6-11-26-25(19-22)27(12-13-28-26)29-23-7-9-24(10-8-23)31-16-14-30(2)15-17-31/h3-13,18-19H,14-17H2,1-2H3,(H,28,29)	LRRFROMGHKZMSA-UHFFFAOYSA-N	50323647	CHEMBL1209122::N-(4-(4-methylpiperazin-1-yl)phenyl)-6-m-tolylquinolin-4-amine	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323647	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323647&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11632886	117644968		CHEMBL1209122				ZINC58538236	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588612	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C26H25ClN4/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-4-20(18-24(25)26)19-2-5-21(27)6-3-19/h2-13,18H,14-17H2,1H3,(H,28,29)	CQERPSZQVAXWHF-UHFFFAOYSA-N	50323635	6-(4-chlorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1208951	MAP kinase-activated protein kinase 2	Homo sapiens	 96								ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11575548	117644956		CHEMBL1208951				ZINC58520190	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588613	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C26H25ClN4/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-4-20(18-24(25)26)19-2-5-21(27)6-3-19/h2-13,18H,14-17H2,1H3,(H,28,29)	CQERPSZQVAXWHF-UHFFFAOYSA-N	50323635	6-(4-chlorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1208951	MAP kinase-activated protein kinase 2	Homo sapiens	 310								ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11575548	117644956		CHEMBL1208951				ZINC58520190	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588614	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C26H25ClN4/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-4-20(18-24(25)26)19-2-5-21(27)6-3-19/h2-13,18H,14-17H2,1H3,(H,28,29)	CQERPSZQVAXWHF-UHFFFAOYSA-N	50323635	6-(4-chlorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1208951	MAP kinase-activated protein kinase 2	Homo sapiens	 480								ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11575548	117644956		CHEMBL1208951				ZINC58520190	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50588615	CN1CCN(CC1)c1ccc(Nc2ccnc3ccc(cc23)-c2ccc(Cl)cc2)cc1	InChI=1S/C26H25ClN4/c1-30-14-16-31(17-15-30)23-9-7-22(8-10-23)29-26-12-13-28-25-11-4-20(18-24(25)26)19-2-5-21(27)6-3-19/h2-13,18H,14-17H2,1H3,(H,28,29)	CQERPSZQVAXWHF-UHFFFAOYSA-N	50323635	6-(4-chlorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)quinolin-4-amine::CHEMBL1208951	MAP kinase-activated protein kinase 2	Homo sapiens	 320								ChEMBL	10.1016/j.bmcl.2010.06.107	10.7270/Q2HX1CVQ	20643547			Olsson, H; Sjo, P; Ersoy, O; Kristoffersson, A; Larsson, J; Norden, B	AstraZeneca R & D Lund	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50323635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50323635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11575548	117644956		CHEMBL1208951				ZINC58520190	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50596690	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C	InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	WINHZLLDWRZWRT-ATVHPVEESA-N	4814	CHEMBL535::N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU11248::SUNITINIB::SUNITINIB MALATE::US10464902, Sunitinib::US9163010, Sunitinib::US9914707, SU11248	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1182/blood-2009-05-222034	10.7270/Q2PN95V2	19654408			Zarrinkar, PP; Gunawardane, RN; Cramer, MD; Gardner, MF; Brigham, D; Belli, B; Karaman, MW; Pratz, KW; Pallares, G; Chao, Q; Sprankle, KG; Patel, HK; Levis, M; Armstrong, RC; James, J; Bhagwat, SS	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4814&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B49	6NG0,4KS8,3G0F,3G0E,2Y7J,6JOK,6M11,3MIY,3TI1,4QMZ,6V0X,6NFZ,6NFY,4AGD	5329102	8034462	38940	CHEMBL535	DB01268	5713		ZINC03964325	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50607552	CC(C)c1n[nH]c(Cl)c1-c1ccnc(Nc2ccc(cn2)N2CCC(CC2)N(C)C)n1	InChI=1S/C22H29ClN8/c1-14(2)20-19(21(23)29-28-20)17-7-10-24-22(26-17)27-18-6-5-16(13-25-18)31-11-8-15(9-12-31)30(3)4/h5-7,10,13-15H,8-9,11-12H2,1-4H3,(H,28,29)(H,24,25,26,27)	JKFGTURSEBTJIZ-UHFFFAOYSA-N	50330261	4-(5-Chloro-3-isopropyl-1H-pyrazol-4-yl)-N-(5-(4-(dimethylamino)piperidin-1-yl)pyridin-2-yl)pyrimidin-2-amine::CHEMBL1272116	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm100571n	10.7270/Q2T72HQV	21038853			Cho, YS; Borland, M; Brain, C; Chen, CH; Cheng, H; Chopra, R; Chung, K; Groarke, J; He, G; Hou, Y; Kim, S; Kovats, S; Lu, Y; O'Reilly, M; Shen, J; Smith, T; Trakshel, G; Vogtle, M; Xu, M; Xu, M; Sung, MJ	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330261	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330261&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49765254	123109376		CHEMBL1272116				ZINC64526521	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50607553	CC(C)c1[nH]nc(c1-c1ccnc(Nc2ccc(cn2)N2CCC(CC2)N(C)C)n1)C(F)(F)F	InChI=1S/C23H29F3N8/c1-14(2)20-19(21(32-31-20)23(24,25)26)17-7-10-27-22(29-17)30-18-6-5-16(13-28-18)34-11-8-15(9-12-34)33(3)4/h5-7,10,13-15H,8-9,11-12H2,1-4H3,(H,31,32)(H,27,28,29,30)	DBZXYASRLGQZEQ-UHFFFAOYSA-N	50330262	CHEMBL1272171::N*6'*-[4-(5-Isopropyl-3-trifluoromethyl-1H-pyrazol-4-yl)-pyrimidin-2-yl]-N*4*,N*4*-dimethyl-3,4,5,6-tetrahydro-2H-[1,3']-bipyridinyl-4,6'-diamine	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm100571n	10.7270/Q2T72HQV	21038853			Cho, YS; Borland, M; Brain, C; Chen, CH; Cheng, H; Chopra, R; Chung, K; Groarke, J; He, G; Hou, Y; Kim, S; Kovats, S; Lu, Y; O'Reilly, M; Shen, J; Smith, T; Trakshel, G; Vogtle, M; Xu, M; Xu, M; Sung, MJ	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50330262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50330262&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49840306	123109377		CHEMBL1272171				ZINC64513936	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50610589	Cc1ccc(cc1NC(=O)c1cnn(c1N)-c1ccccc1F)C(=O)Nc1ccon1	InChI=1S/C21H17FN6O3/c1-12-6-7-13(20(29)26-18-8-9-31-27-18)10-16(12)25-21(30)14-11-24-28(19(14)23)17-5-3-2-4-15(17)22/h2-11H,23H2,1H3,(H,25,30)(H,26,27,29)	HFTDLOVSQHYBFJ-UHFFFAOYSA-N	50331629	5-amino-1-(2-fluorophenyl)-N-(5-(isoxazol-3-ylcarbamoyl)-2-methylphenyl)-1H-pyrazole-4-carboxamide::CHEMBL1290746	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2010.10.034	10.7270/Q2BP0319	21035336			Das, J; Moquin, RV; Dyckman, AJ; Li, T; Pitt, S; Zhang, R; Shen, DR; McIntyre, KW; Gillooly, K; Doweyko, AM; Newitt, JA; Sack, JS; Zhang, H; Kiefer, SE; Kish, K; McKinnon, M; Barrish, JC; Dodd, JH; Schieven, GL; Leftheris, K	Bristol-Myers Squibb Research and Development	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50331629	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50331629&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49838879	123110744		CHEMBL1290746				ZINC64560262	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50646344	Cc1ccc(cc1-n1cnc(OCc2ccc(F)cc2F)c(Cl)c1=O)C(=O)NCCO	InChI=1S/C21H18ClF2N3O4/c1-12-2-3-13(19(29)25-6-7-28)8-17(12)27-11-26-20(18(22)21(27)30)31-10-14-4-5-15(23)9-16(14)24/h2-5,8-9,11,28H,6-7,10H2,1H3,(H,25,29)	XIPYKUQAZQIESI-UHFFFAOYSA-N	50346918	CHEMBL1738710	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2011.05.006	10.7270/Q2G73F2S	21620699			Devadas, B; Selness, SR; Xing, L; Madsen, HM; Marrufo, LD; Shieh, H; Messing, DM; Yang, JZ; Morgan, HM; Anderson, GD; Webb, EG; Zhang, J; Devraj, RV; Monahan, JB	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50346918	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50346918&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	29A	3ROC	11683817	136353604		CHEMBL1738710			C04080	ZINC38240313	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644052	Nc1ncc(Cl)nc1CNC(=S)Nc1ccccc1	InChI=1S/C12H12ClN5S/c13-10-7-15-11(14)9(18-10)6-16-12(19)17-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,14,15)(H2,16,17,19)	VVKMRLPJXUGJLD-UHFFFAOYSA-N	50345814	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783545	MAP kinase-activated protein kinase 2	Homo sapiens		 2000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345814&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580390	131348745		CHEMBL1783545				ZINC71295441	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644053	CCNC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C8H12ClN5S/c1-2-11-8(15)13-3-5-7(10)12-4-6(9)14-5/h4H,2-3H2,1H3,(H2,10,12)(H2,11,13,15)	KIONMZPJMGJNGE-UHFFFAOYSA-N	50345815	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-ethylthiourea::CHEMBL1783546	MAP kinase-activated protein kinase 2	Homo sapiens		 20000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345815&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581389	131348746		CHEMBL1783546				ZINC71295469	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644054	CC(C)NC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C9H14ClN5S/c1-5(2)14-9(16)13-3-6-8(11)12-4-7(10)15-6/h4-5H,3H2,1-2H3,(H2,11,12)(H2,13,14,16)	UWXPNIJJKPJKRH-UHFFFAOYSA-N	50345816	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-isopropylthiourea::CHEMBL1783547	MAP kinase-activated protein kinase 2	Homo sapiens		 13000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345816&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584339	131348747		CHEMBL1783547				ZINC71280885	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644055	CC(C)(C)NC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C10H16ClN5S/c1-10(2,3)16-9(17)14-4-6-8(12)13-5-7(11)15-6/h5H,4H2,1-3H3,(H2,12,13)(H2,14,16,17)	RTEHBLBXENFUKK-UHFFFAOYSA-N	50345817	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-tert-butylthiourea::CHEMBL1783548	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345817&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585307	131348748		CHEMBL1783548				ZINC71280785	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644056	Nc1ncc(Cl)nc1CNC(=S)NC1CC1	InChI=1S/C9H12ClN5S/c10-7-4-12-8(11)6(15-7)3-13-9(16)14-5-1-2-5/h4-5H,1-3H2,(H2,11,12)(H2,13,14,16)	SBMUXEQVQCOSQD-UHFFFAOYSA-N	50345818	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-cyclopropylthiourea::CHEMBL1783549	MAP kinase-activated protein kinase 2	Homo sapiens		 12000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345818&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581390	131348749		CHEMBL1783549				ZINC71294357	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644057	Nc1ncc(Cl)nc1CNC(=S)NC1CCCC1	InChI=1S/C11H16ClN5S/c12-9-6-14-10(13)8(17-9)5-15-11(18)16-7-3-1-2-4-7/h6-7H,1-5H2,(H2,13,14)(H2,15,16,18)	YALLWIHWZPRIIN-UHFFFAOYSA-N	50345819	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-cyclopentylthiourea::CHEMBL1783550	MAP kinase-activated protein kinase 2	Homo sapiens		 53000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345819&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586258	131348750		CHEMBL1783550				ZINC71295218	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644058	Nc1ncc(Cl)nc1CNC(=S)NC1CCCCCC1	InChI=1S/C13H20ClN5S/c14-11-8-16-12(15)10(19-11)7-17-13(20)18-9-5-3-1-2-4-6-9/h8-9H,1-7H2,(H2,15,16)(H2,17,18,20)	BLWIZLGSAQUGFO-UHFFFAOYSA-N	50345820	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-cycloheptylthiourea::CHEMBL1783551	MAP kinase-activated protein kinase 2	Homo sapiens		 35000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345820&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586259	131348751		CHEMBL1783551				ZINC71294320	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644059	Nc1ncc(Cl)nc1CNC(=S)NCc1ccccc1	InChI=1S/C13H14ClN5S/c14-11-8-16-12(15)10(19-11)7-18-13(20)17-6-9-4-2-1-3-5-9/h1-5,8H,6-7H2,(H2,15,16)(H2,17,18,20)	NGFSGOBJMHYALD-UHFFFAOYSA-N	50345821	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-benzylthiourea::CHEMBL1783552	MAP kinase-activated protein kinase 2	Homo sapiens		 36000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345821&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581391	131348752		CHEMBL1783552				ZINC71294921	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644060	Nc1ncc(Cl)nc1CNC(=S)NCCc1ccccc1	InChI=1S/C14H16ClN5S/c15-12-9-18-13(16)11(20-12)8-19-14(21)17-7-6-10-4-2-1-3-5-10/h1-5,9H,6-8H2,(H2,16,18)(H2,17,19,21)	BKRPAPSNFWJOIZ-UHFFFAOYSA-N	50345822	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-phenethylthiourea::CHEMBL1783553	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345822&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583388	131348753		CHEMBL1783553				ZINC71281395	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644061	COCCNC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C9H14ClN5OS/c1-16-3-2-12-9(17)14-4-6-8(11)13-5-7(10)15-6/h5H,2-4H2,1H3,(H2,11,13)(H2,12,14,17)	ZKGMNKNOXKRRIB-UHFFFAOYSA-N	50345823	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-methoxyethyl)thiourea::CHEMBL1783554	MAP kinase-activated protein kinase 2	Homo sapiens		 22000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345823&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581392	131348754		CHEMBL1783554				ZINC71282163	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644062	CCN(CC)CCCNC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C13H23ClN6S/c1-3-20(4-2)7-5-6-16-13(21)18-8-10-12(15)17-9-11(14)19-10/h9H,3-8H2,1-2H3,(H2,15,17)(H2,16,18,21)	AULQDENWSDVWLA-UHFFFAOYSA-N	50345824	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(3-(diethylamino)propyl)thiourea::CHEMBL1783555	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345824&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585308	131348755		CHEMBL1783555				ZINC71281508	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644063	Nc1ncc(Cl)nc1CNC(=S)NC(=O)c1ccccc1	InChI=1S/C13H12ClN5OS/c14-10-7-16-11(15)9(18-10)6-17-13(21)19-12(20)8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,15,16)(H2,17,19,20,21)	SIADAZTWTJJMDN-UHFFFAOYSA-N	50345825	CHEMBL1783556::N-((3-amino-6-chloropyrazin-2-yl)methylcarbamothioyl)benzamide	MAP kinase-activated protein kinase 2	Homo sapiens		 91000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345825&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584340	131348756		CHEMBL1783556				ZINC71280791	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644064	Nc1ncc(Cl)nc1CNC(=S)Nc1cccc2ccccc12	InChI=1S/C16H14ClN5S/c17-14-9-19-15(18)13(21-14)8-20-16(23)22-12-7-3-5-10-4-1-2-6-11(10)12/h1-7,9H,8H2,(H2,18,19)(H2,20,22,23)	DQLNUZMTBDLFAN-UHFFFAOYSA-N	50345826	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(naphthalen-1-yl)thiourea::CHEMBL1783557	MAP kinase-activated protein kinase 2	Homo sapiens		 3200							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345826&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584341	131348757		CHEMBL1783557				ZINC71294509	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644065	Nc1nccnc1CNC(=S)Nc1ccccc1	InChI=1S/C12H13N5S/c13-11-10(14-6-7-15-11)8-16-12(18)17-9-4-2-1-3-5-9/h1-7H,8H2,(H2,13,15)(H2,16,17,18)	JWXYBKHZSDTBIJ-UHFFFAOYSA-N	50345827	1-((3-aminopyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783558	MAP kinase-activated protein kinase 2	Homo sapiens		 32000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345827&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586260	131348758		CHEMBL1783558				ZINC71281080	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644066	Cc1cnc(N)c(CNC(=S)Nc2ccccc2)n1	InChI=1S/C13H15N5S/c1-9-7-15-12(14)11(17-9)8-16-13(19)18-10-5-3-2-4-6-10/h2-7H,8H2,1H3,(H2,14,15)(H2,16,18,19)	XMQQCNXNOUNOSK-UHFFFAOYSA-N	50345828	1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783559	MAP kinase-activated protein kinase 2	Homo sapiens		 4000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345828&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583389	131348759		CHEMBL1783559				ZINC71295496	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644067	CCc1cnc(N)c(CNC(=S)Nc2ccccc2)n1	InChI=1S/C14H17N5S/c1-2-10-8-16-13(15)12(18-10)9-17-14(20)19-11-6-4-3-5-7-11/h3-8H,2,9H2,1H3,(H2,15,16)(H2,17,19,20)	WMYIWTUHBXPYKG-UHFFFAOYSA-N	50345829	1-((3-amino-6-ethylpyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783560	MAP kinase-activated protein kinase 2	Homo sapiens		 1500							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345829&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583390	131348760		CHEMBL1783560				ZINC71281877	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644068	CCCc1cnc(N)c(CNC(=S)Nc2ccccc2)n1	InChI=1S/C15H19N5S/c1-2-6-12-9-17-14(16)13(19-12)10-18-15(21)20-11-7-4-3-5-8-11/h3-5,7-9H,2,6,10H2,1H3,(H2,16,17)(H2,18,20,21)	NMTJJQDRWWVJTO-UHFFFAOYSA-N	50345830	1-((3-amino-6-propylpyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783561	MAP kinase-activated protein kinase 2	Homo sapiens		 2300							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345830&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585309	131348761		CHEMBL1783561				ZINC71281821	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644069	Nc1ncc(nc1CNC(=S)Nc1ccccc1)C(F)(F)F	InChI=1S/C13H12F3N5S/c14-13(15,16)10-7-18-11(17)9(21-10)6-19-12(22)20-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,17,18)(H2,19,20,22)	RSCNMEYSYWZTAQ-UHFFFAOYSA-N	50345831	1-((3-amino-6-(trifluoromethyl)pyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783562	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345831&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586261	131348762		CHEMBL1783562				ZINC71295315	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644070	Nc1ncc(nc1CNC(=S)Nc1ccccc1)C1CC1	InChI=1S/C15H17N5S/c16-14-13(20-12(8-17-14)10-6-7-10)9-18-15(21)19-11-4-2-1-3-5-11/h1-5,8,10H,6-7,9H2,(H2,16,17)(H2,18,19,21)	OYCYWWONYAEJKA-UHFFFAOYSA-N	50345832	1-((3-amino-6-cyclopropylpyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783563	MAP kinase-activated protein kinase 2	Homo sapiens		 470							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345832&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583391	131348763		CHEMBL1783563				ZINC71294698	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644071	Nc1ncc(nc1CNC(=S)Nc1ccccc1)-c1ccccc1	InChI=1S/C18H17N5S/c19-17-16(12-21-18(24)22-14-9-5-2-6-10-14)23-15(11-20-17)13-7-3-1-4-8-13/h1-11H,12H2,(H2,19,20)(H2,21,22,24)	INTRZYKIVFXSEA-UHFFFAOYSA-N	50345833	1-((3-amino-6-phenylpyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783564	MAP kinase-activated protein kinase 2	Homo sapiens		 50000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345833&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582407	131348764		CHEMBL1783564				ZINC71295887	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644072	CN(C)c1nc(N)c(CNC(=S)Nc2ccccc2)nc1Cl	InChI=1S/C14H17ClN6S/c1-21(2)13-11(15)19-10(12(16)20-13)8-17-14(22)18-9-6-4-3-5-7-9/h3-7H,8H2,1-2H3,(H2,16,20)(H2,17,18,22)	HYJJPOZXQOGARJ-UHFFFAOYSA-N	50345834	1-((3-amino-6-chloro-5-(dimethylamino)pyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783565	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345834&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582408	131348765		CHEMBL1783565				ZINC71295260	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644073	CCOc1nc(N)c(CNC(=S)Nc2ccccc2)nc1Cl	InChI=1S/C14H16ClN5OS/c1-2-21-13-11(15)19-10(12(16)20-13)8-17-14(22)18-9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H2,16,20)(H2,17,18,22)	VQBMVUYFBJUNNB-UHFFFAOYSA-N	50345835	1-((3-amino-6-chloro-5-ethoxypyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783566	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345835&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583392	131348766		CHEMBL1783566				ZINC71280577	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644074	CSc1nc(N)c(CNC(=S)Nc2ccccc2)nc1Cl	InChI=1S/C13H14ClN5S2/c1-21-12-10(14)18-9(11(15)19-12)7-16-13(20)17-8-5-3-2-4-6-8/h2-6H,7H2,1H3,(H2,15,19)(H2,16,17,20)	JGKVCVHKZPGCIL-UHFFFAOYSA-N	50345836	1-((3-amino-6-chloro-5-(methylthio)pyrazin-2-yl)methyl)-3-phenylthiourea::CHEMBL1783567	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345836&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585310	131348767		CHEMBL1783567				ZINC71280453	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644075	Cc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C13H14ClN5S/c1-8-2-4-9(5-3-8)18-13(20)17-6-10-12(15)16-7-11(14)19-10/h2-5,7H,6H2,1H3,(H2,15,16)(H2,17,18,20)	IPYNNMGPCOXAOL-UHFFFAOYSA-N	50345837	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-p-tolylthiourea::CHEMBL1783568	MAP kinase-activated protein kinase 2	Homo sapiens		 2700							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345837&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580391	131348768		CHEMBL1783568				ZINC71295662	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644076	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(Cl)cc1	InChI=1S/C12H11Cl2N5S/c13-7-1-3-8(4-2-7)18-12(20)17-5-9-11(15)16-6-10(14)19-9/h1-4,6H,5H2,(H2,15,16)(H2,17,18,20)	FATZSGFQHPMMBP-UHFFFAOYSA-N	50345838	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-chlorophenyl)thiourea::CHEMBL1783569	MAP kinase-activated protein kinase 2	Homo sapiens		 3700							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345838&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580392	131348769		CHEMBL1783569				ZINC71294555	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644077	COc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C13H14ClN5OS/c1-20-9-4-2-8(3-5-9)18-13(21)17-6-10-12(15)16-7-11(14)19-10/h2-5,7H,6H2,1H3,(H2,15,16)(H2,17,18,21)	PPPFVDDAHQIPCX-UHFFFAOYSA-N	50345839	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-methoxyphenyl)thiourea::CHEMBL1783570	MAP kinase-activated protein kinase 2	Homo sapiens		 1900							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345839&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584342	131348770		CHEMBL1783570				ZINC71294712	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644078	CC(C)c1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C15H18ClN5S/c1-9(2)10-3-5-11(6-4-10)20-15(22)19-7-12-14(17)18-8-13(16)21-12/h3-6,8-9H,7H2,1-2H3,(H2,17,18)(H2,19,20,22)	JFQMIWAICVQARM-UHFFFAOYSA-N	50345840	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-isopropylphenyl)thiourea::CHEMBL1783571	MAP kinase-activated protein kinase 2	Homo sapiens		 2600							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345840&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581393	131348771		CHEMBL1783571				ZINC71295971	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644079	CC(C)(C)c1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C16H20ClN5S/c1-16(2,3)10-4-6-11(7-5-10)21-15(23)20-8-12-14(18)19-9-13(17)22-12/h4-7,9H,8H2,1-3H3,(H2,18,19)(H2,20,21,23)	IAJFOPLYGAQAOU-UHFFFAOYSA-N	50345841	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-tert-butylphenyl)thiourea::CHEMBL1783572	MAP kinase-activated protein kinase 2	Homo sapiens		 13700							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345841&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587285	131348772		CHEMBL1783572				ZINC71295283	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644080	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(Br)cc1	InChI=1S/C12H11BrClN5S/c13-7-1-3-8(4-2-7)18-12(20)17-5-9-11(15)16-6-10(14)19-9/h1-4,6H,5H2,(H2,15,16)(H2,17,18,20)	JQIOJIUDRDIFJN-UHFFFAOYSA-N	50345842	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-bromophenyl)thiourea::CHEMBL1783573	MAP kinase-activated protein kinase 2	Homo sapiens		 3100							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345842&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583393	131348773		CHEMBL1783573				ZINC71295263	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644081	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(cc1)[N+]([O-])=O	InChI=1S/C12H11ClN6O2S/c13-10-6-15-11(14)9(18-10)5-16-12(22)17-7-1-3-8(4-2-7)19(20)21/h1-4,6H,5H2,(H2,14,15)(H2,16,17,22)	CWHBTWGSDNZUKL-UHFFFAOYSA-N	50345843	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-nitrophenyl)thiourea::CHEMBL1783574	MAP kinase-activated protein kinase 2	Homo sapiens		 9900							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345843&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581394	131348774		CHEMBL1783574				ZINC71296026	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644082	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(cc1)C#N	InChI=1S/C13H11ClN6S/c14-11-7-17-12(16)10(20-11)6-18-13(21)19-9-3-1-8(5-15)2-4-9/h1-4,7H,6H2,(H2,16,17)(H2,18,19,21)	DVJXYWRSCYOJLL-UHFFFAOYSA-N	50345844	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-cyanophenyl)thiourea::CHEMBL1783575	MAP kinase-activated protein kinase 2	Homo sapiens		 6900							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345844&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586262	131348775		CHEMBL1783575				ZINC71295373	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644083	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(cc1)-n1cnnn1	InChI=1S/C13H12ClN9S/c14-11-6-16-12(15)10(20-11)5-17-13(24)19-8-1-3-9(4-2-8)23-7-18-21-22-23/h1-4,6-7H,5H2,(H2,15,16)(H2,17,19,24)	SQVKHWHCQUYWGV-UHFFFAOYSA-N	50345845	1-(4-(1H-tetrazol-1-yl)phenyl)-3-((3-amino-6-chloropyrazin-2-yl)methyl)thiourea::CHEMBL1783576	MAP kinase-activated protein kinase 2	Homo sapiens		>40000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345845&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581395	131348776		CHEMBL1783576				ZINC71294487	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644084	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(OCc2ccccc2)cc1	InChI=1S/C19H18ClN5OS/c20-17-11-22-18(21)16(25-17)10-23-19(27)24-14-6-8-15(9-7-14)26-12-13-4-2-1-3-5-13/h1-9,11H,10,12H2,(H2,21,22)(H2,23,24,27)	ZYVDCPXIDNKMDI-UHFFFAOYSA-N	50345846	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-(benzyloxy)phenyl)thiourea::CHEMBL1783577	MAP kinase-activated protein kinase 2	Homo sapiens		 2700							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345846&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587286	131348777		CHEMBL1783577				ZINC71281841	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644085	CC(=O)c1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C14H14ClN5OS/c1-8(21)9-2-4-10(5-3-9)19-14(22)18-6-11-13(16)17-7-12(15)20-11/h2-5,7H,6H2,1H3,(H2,16,17)(H2,18,19,22)	WOEGIMHRZSPXAC-UHFFFAOYSA-N	50345847	1-(4-acetylphenyl)-3-((3-amino-6-chloropyrazin-2-yl)methyl)thiourea::CHEMBL1783578	MAP kinase-activated protein kinase 2	Homo sapiens		 6900							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345847	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345847&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587287	131348778		CHEMBL1783578				ZINC71295955	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644086	CCOC(=O)c1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C15H16ClN5O2S/c1-2-23-14(22)9-3-5-10(6-4-9)20-15(24)19-7-11-13(17)18-8-12(16)21-11/h3-6,8H,2,7H2,1H3,(H2,17,18)(H2,19,20,24)	WPNUXZGJUMKSTO-UHFFFAOYSA-N	50345848	CHEMBL1783579::ethyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)benzoate	MAP kinase-activated protein kinase 2	Homo sapiens		 10700							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345848&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580393	131348779		CHEMBL1783579				ZINC71280730	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644087	CN(C)c1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C14H17ClN6S/c1-21(2)10-5-3-9(4-6-10)19-14(22)18-7-11-13(16)17-8-12(15)20-11/h3-6,8H,7H2,1-2H3,(H2,16,17)(H2,18,19,22)	HHUNCHPIUIFIIS-UHFFFAOYSA-N	50345849	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-(dimethylamino)phenyl)thiourea::CHEMBL1783580	MAP kinase-activated protein kinase 2	Homo sapiens		 7000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345849&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585311	131348780		CHEMBL1783580				ZINC71294650	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644088	CC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C14H15ClN6OS/c1-8(22)19-9-2-4-10(5-3-9)20-14(23)18-6-11-13(16)17-7-12(15)21-11/h2-5,7H,6H2,1H3,(H2,16,17)(H,19,22)(H2,18,20,23)	YMOJMSSSDLYCBT-UHFFFAOYSA-N	50345850	CHEMBL1783581::N-(4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenyl)acetamide	MAP kinase-activated protein kinase 2	Homo sapiens		 5200							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345850&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581396	131348781		CHEMBL1783581				ZINC71281274	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644089	Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C12H13ClN6S/c13-10-6-16-11(15)9(19-10)5-17-12(20)18-8-3-1-7(14)2-4-8/h1-4,6H,5,14H2,(H2,15,16)(H2,17,18,20)	YVNZHRRWKGKCOA-UHFFFAOYSA-N	50345851	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(4-aminophenyl)thiourea::CHEMBL1783669	MAP kinase-activated protein kinase 2	Homo sapiens		 2000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345851&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587326	131348782		CHEMBL1783669				ZINC71280690	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644090	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(NC(=O)OCc2ccccc2)cc1	InChI=1S/C20H19ClN6O2S/c21-17-11-23-18(22)16(27-17)10-24-19(30)25-14-6-8-15(9-7-14)26-20(28)29-12-13-4-2-1-3-5-13/h1-9,11H,10,12H2,(H2,22,23)(H,26,28)(H2,24,25,30)	ZDPYBWXNXMKLOY-UHFFFAOYSA-N	50345852	CHEMBL1783670::benzyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 460							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345852&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586298	131348783		CHEMBL1783670				ZINC71295228	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644091	Cc1ccccc1NC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C13H14ClN5S/c1-8-4-2-3-5-9(8)19-13(20)17-6-10-12(15)16-7-11(14)18-10/h2-5,7H,6H2,1H3,(H2,15,16)(H2,17,19,20)	DZQSUONHCMWRFF-UHFFFAOYSA-N	50345853	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-o-tolylthiourea::CHEMBL1783671	MAP kinase-activated protein kinase 2	Homo sapiens		 3600							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345853	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345853&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582441	131348784		CHEMBL1783671				ZINC71280787	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644092	Nc1ncc(Cl)nc1CNC(=S)Nc1ccccc1Cl	InChI=1S/C12H11Cl2N5S/c13-7-3-1-2-4-8(7)19-12(20)17-5-9-11(15)16-6-10(14)18-9/h1-4,6H,5H2,(H2,15,16)(H2,17,19,20)	BIEVFPHFDCQCQQ-UHFFFAOYSA-N	50345854	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-chlorophenyl)thiourea::CHEMBL1783672	MAP kinase-activated protein kinase 2	Homo sapiens		 1100							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345854	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345854&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586299	131348785		CHEMBL1783672				ZINC71294812	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644093	COc1ccccc1NC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C13H14ClN5OS/c1-20-10-5-3-2-4-8(10)19-13(21)17-6-9-12(15)16-7-11(14)18-9/h2-5,7H,6H2,1H3,(H2,15,16)(H2,17,19,21)	FHWSALCCHXXIDJ-UHFFFAOYSA-N	50345855	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-methoxyphenyl)thiourea::CHEMBL1783673	MAP kinase-activated protein kinase 2	Homo sapiens		 2600							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345855	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345855&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580426	131348786		CHEMBL1783673				ZINC71294608	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644094	Nc1ncc(Cl)nc1CNC(=S)Nc1ccccc1F	InChI=1S/C12H11ClFN5S/c13-10-6-16-11(15)9(18-10)5-17-12(20)19-8-4-2-1-3-7(8)14/h1-4,6H,5H2,(H2,15,16)(H2,17,19,20)	QRXURFDWKYLLBV-UHFFFAOYSA-N	50345856	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-fluorophenyl)thiourea::CHEMBL1783674	MAP kinase-activated protein kinase 2	Homo sapiens		 2000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345856	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345856&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583423	131348787		CHEMBL1783674				ZINC71295575	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644095	CSc1ccccc1NC(=S)NCc1nc(Cl)cnc1N	InChI=1S/C13H14ClN5S2/c1-21-10-5-3-2-4-8(10)19-13(20)17-6-9-12(15)16-7-11(14)18-9/h2-5,7H,6H2,1H3,(H2,15,16)(H2,17,19,20)	MNGBOMSYSNDYPE-UHFFFAOYSA-N	50345857	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2-(methylthio)phenyl)thiourea::CHEMBL1783675	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345857	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345857&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586300	131348788		CHEMBL1783675				ZINC71296045	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644096	Nc1ncc(Cl)nc1CNC(=S)Nc1ccccc1-c1ccccc1	InChI=1S/C18H16ClN5S/c19-16-11-21-17(20)15(23-16)10-22-18(25)24-14-9-5-4-8-13(14)12-6-2-1-3-7-12/h1-9,11H,10H2,(H2,20,21)(H2,22,24,25)	SRTVMHQDRWLGAR-UHFFFAOYSA-N	50345858	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(biphenyl-2-yl)thiourea::CHEMBL1783676	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345858	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345858&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584380	131348789		CHEMBL1783676				ZINC71281321	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644097	Cc1cccc(NC(=S)NCc2nc(Cl)cnc2N)c1	InChI=1S/C13H14ClN5S/c1-8-3-2-4-9(5-8)18-13(20)17-6-10-12(15)16-7-11(14)19-10/h2-5,7H,6H2,1H3,(H2,15,16)(H2,17,18,20)	BPOXGDXNXMGKPJ-UHFFFAOYSA-N	50345859	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-m-tolylthiourea::CHEMBL1783677	MAP kinase-activated protein kinase 2	Homo sapiens		 9300							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345859	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345859&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585338	131348790		CHEMBL1783677				ZINC71294905	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644098	Nc1ncc(Cl)nc1CNC(=S)Nc1cccc(Cl)c1	InChI=1S/C12H11Cl2N5S/c13-7-2-1-3-8(4-7)18-12(20)17-5-9-11(15)16-6-10(14)19-9/h1-4,6H,5H2,(H2,15,16)(H2,17,18,20)	SJNVJQNNXYYLDQ-UHFFFAOYSA-N	50345860	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(3-chlorophenyl)thiourea::CHEMBL1783678	MAP kinase-activated protein kinase 2	Homo sapiens		 11300							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345860&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587327	131348791		CHEMBL1783678				ZINC71295129	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644099	COc1cccc(NC(=S)NCc2nc(Cl)cnc2N)c1	InChI=1S/C13H14ClN5OS/c1-20-9-4-2-3-8(5-9)18-13(21)17-6-10-12(15)16-7-11(14)19-10/h2-5,7H,6H2,1H3,(H2,15,16)(H2,17,18,21)	YQNHEZMGXWWWOZ-UHFFFAOYSA-N	50345861	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(3-methoxyphenyl)thiourea::CHEMBL1783679	MAP kinase-activated protein kinase 2	Homo sapiens		 14500							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345861&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583424	131348792		CHEMBL1783679				ZINC71281403	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644100	COc1ccc(NC(=S)NCc2nc(Cl)cnc2N)c(OC)c1	InChI=1S/C14H16ClN5O2S/c1-21-8-3-4-9(11(5-8)22-2)20-14(23)18-6-10-13(16)17-7-12(15)19-10/h3-5,7H,6H2,1-2H3,(H2,16,17)(H2,18,20,23)	OQZVSWDFZHBRDG-UHFFFAOYSA-N	50345862	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2,4-dimethoxyphenyl)thiourea::CHEMBL1783680	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345862&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582442	131348793		CHEMBL1783680				ZINC71294777	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644101	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(Cl)cc1Cl	InChI=1S/C12H10Cl3N5S/c13-6-1-2-8(7(14)3-6)20-12(21)18-4-9-11(16)17-5-10(15)19-9/h1-3,5H,4H2,(H2,16,17)(H2,18,20,21)	HJUJLSBWLJBWSR-UHFFFAOYSA-N	50345863	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(2,4-dichlorophenyl)thiourea::CHEMBL1783681	MAP kinase-activated protein kinase 2	Homo sapiens		 4300							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345863&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586301	131348794		CHEMBL1783681				ZINC71296073	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644102	COc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1OC	InChI=1S/C14H16ClN5O2S/c1-21-10-4-3-8(5-11(10)22-2)19-14(23)18-6-9-13(16)17-7-12(15)20-9/h3-5,7H,6H2,1-2H3,(H2,16,17)(H2,18,19,23)	WQZGKMQKSLFOOR-UHFFFAOYSA-N	50345864	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(3,4-dimethoxyphenyl)thiourea::CHEMBL1783682	MAP kinase-activated protein kinase 2	Homo sapiens		 40000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345864&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587328	131348795		CHEMBL1783682				ZINC71281219	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644103	Nc1ncc(Cl)nc1CNC(=S)Nc1ccc(Cl)c(Cl)c1	InChI=1S/C12H10Cl3N5S/c13-7-2-1-6(3-8(7)14)19-12(21)18-4-9-11(16)17-5-10(15)20-9/h1-3,5H,4H2,(H2,16,17)(H2,18,19,21)	VLFWNTUMLQMMBV-UHFFFAOYSA-N	50345865	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(3,4-dichlorophenyl)thiourea::CHEMBL1783683	MAP kinase-activated protein kinase 2	Homo sapiens		 40000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345865&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580427	131348796		CHEMBL1783683				ZINC71295915	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644104	Nc1ncc(Cl)nc1CNC(=S)Nc1cc(Cl)cc(Cl)c1	InChI=1S/C12H10Cl3N5S/c13-6-1-7(14)3-8(2-6)19-12(21)18-4-9-11(16)17-5-10(15)20-9/h1-3,5H,4H2,(H2,16,17)(H2,18,19,21)	OKKIRFVLOKJGRI-UHFFFAOYSA-N	50345866	1-((3-amino-6-chloropyrazin-2-yl)methyl)-3-(3,5-dichlorophenyl)thiourea::CHEMBL1783684	MAP kinase-activated protein kinase 2	Homo sapiens		 27000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345866&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584381	131348797		CHEMBL1783684				ZINC71294295	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644105	COC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C14H15ClN6O2S/c1-23-14(22)20-9-4-2-8(3-5-9)19-13(24)18-6-10-12(16)17-7-11(15)21-10/h2-5,7H,6H2,1H3,(H2,16,17)(H,20,22)(H2,18,19,24)	SKFTUSWASLNCHF-UHFFFAOYSA-N	50345867	CHEMBL1783685::methyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 940							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345867&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587329	131348798		CHEMBL1783685				ZINC71295840	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644106	CCOC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C15H17ClN6O2S/c1-2-24-15(23)21-10-5-3-9(4-6-10)20-14(25)19-7-11-13(17)18-8-12(16)22-11/h3-6,8H,2,7H2,1H3,(H2,17,18)(H,21,23)(H2,19,20,25)	MJLYWJVCOTUCNN-UHFFFAOYSA-N	50345868	CHEMBL1783686::ethyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 310							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345868&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582443	131348799		CHEMBL1783686				ZINC71294824	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644107	CCCCOC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C17H21ClN6O2S/c1-2-3-8-26-17(25)23-12-6-4-11(5-7-12)22-16(27)21-9-13-15(19)20-10-14(18)24-13/h4-7,10H,2-3,8-9H2,1H3,(H2,19,20)(H,23,25)(H2,21,22,27)	FQMLLSSXUJLUMX-UHFFFAOYSA-N	50345869	CHEMBL1783687::butyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 230							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345869&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585339	131348800		CHEMBL1783687				ZINC71294289	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644108	CC(C)COC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C17H21ClN6O2S/c1-10(2)9-26-17(25)23-12-5-3-11(4-6-12)22-16(27)21-7-13-15(19)20-8-14(18)24-13/h3-6,8,10H,7,9H2,1-2H3,(H2,19,20)(H,23,25)(H2,21,22,27)	FFEKZMDUFVLJQZ-UHFFFAOYSA-N	50345870	CHEMBL1783688::isobutyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 150							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345870&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584382	131348801		CHEMBL1783688				ZINC71295744	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644109	CC(C)(C)OC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C17H21ClN6O2S/c1-17(2,3)26-16(25)23-11-6-4-10(5-7-11)22-15(27)21-8-12-14(19)20-9-13(18)24-12/h4-7,9H,8H2,1-3H3,(H2,19,20)(H,23,25)(H2,21,22,27)	DCHCUJLYTWHIHV-UHFFFAOYSA-N	50345871	CHEMBL1783689::tert-butyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 190							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345871&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587330	131348802		CHEMBL1783689				ZINC71294439	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644110	CC(C)COC(=O)N(c1ccccc1)c1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C23H25ClN6O2S/c1-15(2)14-32-23(31)30(17-6-4-3-5-7-17)18-10-8-16(9-11-18)28-22(33)27-12-19-21(25)26-13-20(24)29-19/h3-11,13,15H,12,14H2,1-2H3,(H2,25,26)(H2,27,28,33)	LSVNWNAWSWKXBH-UHFFFAOYSA-N	50345872	CHEMBL1783668::isobutyl 4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenyl(phenyl)carbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 1500							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345872&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582440	131348803		CHEMBL1783668				ZINC71294832	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644111	CNC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C14H16ClN7OS/c1-17-13(23)20-8-2-4-9(5-3-8)21-14(24)19-6-10-12(16)18-7-11(15)22-10/h2-5,7H,6H2,1H3,(H2,16,18)(H2,17,20,23)(H2,19,21,24)	UXEOXAAYWDRBFA-UHFFFAOYSA-N	50345873	1-(4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenyl)-3-methylurea::CHEMBL1783690	MAP kinase-activated protein kinase 2	Homo sapiens		 1700							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345873&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586302	131348804		CHEMBL1783690				ZINC71295491	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644112	CC(C)(C)NC(=O)Nc1ccc(NC(=S)NCc2nc(Cl)cnc2N)cc1	InChI=1S/C17H22ClN7OS/c1-17(2,3)25-15(26)22-10-4-6-11(7-5-10)23-16(27)21-8-12-14(19)20-9-13(18)24-12/h4-7,9H,8H2,1-3H3,(H2,19,20)(H2,21,23,27)(H2,22,25,26)	VIIGGPVWUFWOHP-UHFFFAOYSA-N	50345874	1-(4-(3-((3-amino-6-chloropyrazin-2-yl)methyl)thioureido)phenyl)-3-tert-butylurea::CHEMBL1783691	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345874&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582444	131348805		CHEMBL1783691				ZINC71282024	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644113	Cc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)OC(C)(C)C)cc2)n1	InChI=1S/C18H24N6O2S/c1-11-9-20-15(19)14(22-11)10-21-16(27)23-12-5-7-13(8-6-12)24-17(25)26-18(2,3)4/h5-9H,10H2,1-4H3,(H2,19,20)(H,24,25)(H2,21,23,27)	LHXWADILMLDNGD-UHFFFAOYSA-N	50345875	CHEMBL1783692::tert-butyl 4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 210							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345875&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580428	131348806		CHEMBL1783692				ZINC71280776	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644114	Cc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)Oc3ccccc3)cc2)n1	InChI=1S/C20H20N6O2S/c1-13-11-22-18(21)17(24-13)12-23-19(29)25-14-7-9-15(10-8-14)26-20(27)28-16-5-3-2-4-6-16/h2-11H,12H2,1H3,(H2,21,22)(H,26,27)(H2,23,25,29)	NNECYYSZYOEFRF-UHFFFAOYSA-N	50345876	CHEMBL1783693::phenyl 4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 730							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345876&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581434	131348807		CHEMBL1783693				ZINC71294348	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644115	CCOC(=O)N(C)c1ccc(NC(=S)NCc2nc(C)cnc2N)cc1	InChI=1S/C17H22N6O2S/c1-4-25-17(24)23(3)13-7-5-12(6-8-13)22-16(26)20-10-14-15(18)19-9-11(2)21-14/h5-9H,4,10H2,1-3H3,(H2,18,19)(H2,20,22,26)	UVFQIUDUJVJHRR-UHFFFAOYSA-N	50345877	CHEMBL1783694::ethyl 4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenyl(methyl)carbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 10000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345877&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584383	131348808		CHEMBL1783694				ZINC71295726	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644116	Cc1cnc(N)c(CNC(=S)Nc2ccc(OC(=O)OC(C)(C)C)cc2)n1	InChI=1S/C18H23N5O3S/c1-11-9-20-15(19)14(22-11)10-21-16(27)23-12-5-7-13(8-6-12)25-17(24)26-18(2,3)4/h5-9H,10H2,1-4H3,(H2,19,20)(H2,21,23,27)	DCFABICHFBVXIW-UHFFFAOYSA-N	50345878	4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenyl tert-butyl carbonate::CHEMBL1783695	MAP kinase-activated protein kinase 2	Homo sapiens		 2900							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345878&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581435	131348809		CHEMBL1783695				ZINC71295207	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644117	CCC(=O)Nc1ccc(NC(=S)NCc2nc(C)cnc2N)cc1	InChI=1S/C16H20N6OS/c1-3-14(23)21-11-4-6-12(7-5-11)22-16(24)19-9-13-15(17)18-8-10(2)20-13/h4-8H,3,9H2,1-2H3,(H2,17,18)(H,21,23)(H2,19,22,24)	GQZJEOGSPSVJIX-UHFFFAOYSA-N	50345879	CHEMBL1783696::N-(4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenyl)propionamide	MAP kinase-activated protein kinase 2	Homo sapiens		 13300							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345879&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586303	131348810		CHEMBL1783696				ZINC71295689	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644118	CCCC(=O)Nc1ccc(NC(=S)NCc2nc(C)cnc2N)cc1	InChI=1S/C17H22N6OS/c1-3-4-15(24)22-12-5-7-13(8-6-12)23-17(25)20-10-14-16(18)19-9-11(2)21-14/h5-9H,3-4,10H2,1-2H3,(H2,18,19)(H,22,24)(H2,20,23,25)	BJRWKMDBESJWCF-UHFFFAOYSA-N	50345880	CHEMBL1783697::N-(4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenyl)butyramide	MAP kinase-activated protein kinase 2	Homo sapiens		 2300							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345880&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584384	131348811		CHEMBL1783697				ZINC71294440	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644119	CCCCC(=O)Nc1ccc(NC(=S)NCc2nc(C)cnc2N)cc1	InChI=1S/C18H24N6OS/c1-3-4-5-16(25)23-13-6-8-14(9-7-13)24-18(26)21-11-15-17(19)20-10-12(2)22-15/h6-10H,3-5,11H2,1-2H3,(H2,19,20)(H,23,25)(H2,21,24,26)	FKGPIULOTGOVON-UHFFFAOYSA-N	50345881	CHEMBL1783698::N-(4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenyl)pentanamide	MAP kinase-activated protein kinase 2	Homo sapiens		 1500							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345881&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585340	131348812		CHEMBL1783698				ZINC71294622	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644120	Cc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)Cc3ccccc3)cc2)n1	InChI=1S/C21H22N6OS/c1-14-12-23-20(22)18(25-14)13-24-21(29)27-17-9-7-16(8-10-17)26-19(28)11-15-5-3-2-4-6-15/h2-10,12H,11,13H2,1H3,(H2,22,23)(H,26,28)(H2,24,27,29)	RGFWVHRUBRDIJX-UHFFFAOYSA-N	50345882	CHEMBL1783699::N-(4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenyl)-2-phenylacetamide	MAP kinase-activated protein kinase 2	Homo sapiens		 3800							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345882&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580429	131348813		CHEMBL1783699				ZINC71295009	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644121	Cc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)c3ccccc3)cc2)n1	InChI=1S/C20H20N6OS/c1-13-11-22-18(21)17(24-13)12-23-20(28)26-16-9-7-15(8-10-16)25-19(27)14-5-3-2-4-6-14/h2-11H,12H2,1H3,(H2,21,22)(H,25,27)(H2,23,26,28)	YXQPOBXZIXMTFQ-UHFFFAOYSA-N	50345883	CHEMBL1783700::N-(4-(3-((3-amino-6-methylpyrazin-2-yl)methyl)thioureido)phenyl)benzamide	MAP kinase-activated protein kinase 2	Homo sapiens		 580							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345883&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583425	131348814		CHEMBL1783700				ZINC71294380	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644122	Cc1cnc(N)c(CNC(=S)Nc2ccc3[nH]c(=O)oc3c2)n1	InChI=1S/C14H14N6O2S/c1-7-5-16-12(15)10(18-7)6-17-13(23)19-8-2-3-9-11(4-8)22-14(21)20-9/h2-5H,6H2,1H3,(H2,15,16)(H,20,21)(H2,17,19,23)	GTXVJHIQOSTBTI-UHFFFAOYSA-N	50345884	1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)thiourea::CHEMBL1783701	MAP kinase-activated protein kinase 2	Homo sapiens		 210							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345884&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586304	131348815		CHEMBL1783701				ZINC71295545	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644123	Cc1cnc(N)c(CNC(=S)Nc2ccc3[nH]c(=O)[nH]c3c2)n1	InChI=1S/C14H15N7OS/c1-7-5-16-12(15)11(18-7)6-17-14(23)19-8-2-3-9-10(4-8)21-13(22)20-9/h2-5H,6H2,1H3,(H2,15,16)(H2,17,19,23)(H2,20,21,22)	ZEAFIDLGMAIADD-UHFFFAOYSA-N	50345885	1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-(2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea::CHEMBL1783702	MAP kinase-activated protein kinase 2	Homo sapiens		 15000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345885&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586305	131348816		CHEMBL1783702				ZINC71295605	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644124	Cc1cnc(N)c(CNC(=S)Nc2ccc3NC(=O)Cc3c2)n1	InChI=1S/C15H16N6OS/c1-8-6-17-14(16)12(19-8)7-18-15(23)20-10-2-3-11-9(4-10)5-13(22)21-11/h2-4,6H,5,7H2,1H3,(H2,16,17)(H,21,22)(H2,18,20,23)	ZASJHWXKQMGTHA-UHFFFAOYSA-N	50345886	1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-(2-oxoindolin-5-yl)thiourea::CHEMBL1783703	MAP kinase-activated protein kinase 2	Homo sapiens		 27000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345886&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586306	131348817		CHEMBL1783703				ZINC71281984	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644125	Cc1cnc(N)c(CNC(=S)Nc2ccc3[nH]c(=O)sc3c2)n1	InChI=1S/C14H14N6OS2/c1-7-5-16-12(15)10(18-7)6-17-13(22)19-8-2-3-9-11(4-8)23-14(21)20-9/h2-5H,6H2,1H3,(H2,15,16)(H,20,21)(H2,17,19,22)	UPKCVHNIZODZBW-UHFFFAOYSA-N	50345887	1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-(2-oxo-2,3-dihydrobenzo[d]thiazol-6-yl)thiourea::CHEMBL1783704	MAP kinase-activated protein kinase 2	Homo sapiens		 15000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345887&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580430	131348818		CHEMBL1783704				ZINC71280847	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644126	Cc1cnc(N)c(CNC(=S)Nc2ccc3oc(=O)[nH]c3c2)n1	InChI=1S/C14H14N6O2S/c1-7-5-16-12(15)10(18-7)6-17-13(23)19-8-2-3-11-9(4-8)20-14(21)22-11/h2-5H,6H2,1H3,(H2,15,16)(H,20,21)(H2,17,19,23)	XHWYIDSLVDAPOA-UHFFFAOYSA-N	50345888	1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)thiourea::CHEMBL1783705	MAP kinase-activated protein kinase 2	Homo sapiens		 14000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345888&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581436	131348819		CHEMBL1783705				ZINC71281192	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644127	Cc1cnc(N)c(CNC(=S)Nc2ccc3n(C)c(=O)[nH]c3c2)n1	InChI=1S/C15H17N7OS/c1-8-6-17-13(16)11(19-8)7-18-14(24)20-9-3-4-12-10(5-9)21-15(23)22(12)2/h3-6H,7H2,1-2H3,(H2,16,17)(H,21,23)(H2,18,20,24)	XPDBBCLPRMILPN-UHFFFAOYSA-N	50345889	1-((3-amino-6-methylpyrazin-2-yl)methyl)-3-(1-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)thiourea::CHEMBL1783706	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584385	131348820		CHEMBL1783706				ZINC71282287	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644128	CCc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)OC(C)(C)C)cc2)n1	InChI=1S/C19H26N6O2S/c1-5-12-10-21-16(20)15(23-12)11-22-17(28)24-13-6-8-14(9-7-13)25-18(26)27-19(2,3)4/h6-10H,5,11H2,1-4H3,(H2,20,21)(H,25,26)(H2,22,24,28)	ATQFANHXMGLCLY-UHFFFAOYSA-N	50345890	CHEMBL1783707::tert-butyl 4-(3-((3-amino-6-ethylpyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 140							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345890&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584386	131348821		CHEMBL1783707				ZINC71295807	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644129	CCCc1cnc(N)c(CNC(=S)Nc2ccc(NC(=O)OC(C)(C)C)cc2)n1	InChI=1S/C20H28N6O2S/c1-5-6-15-11-22-17(21)16(24-15)12-23-18(29)25-13-7-9-14(10-8-13)26-19(27)28-20(2,3)4/h7-11H,5-6,12H2,1-4H3,(H2,21,22)(H,26,27)(H2,23,25,29)	TVGLRNNXRUFLFX-UHFFFAOYSA-N	50345891	CHEMBL1783708::tert-butyl 4-(3-((3-amino-6-propylpyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 45							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345891	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345891&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44224182	131348822		CHEMBL1783708				ZINC71281623	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644130	CC(C)(C)OC(=O)Nc1ccc(NC(=S)NCc2nc(cnc2N)C2CC2)cc1	InChI=1S/C20H26N6O2S/c1-20(2,3)28-19(27)25-14-8-6-13(7-9-14)24-18(29)23-11-16-17(21)22-10-15(26-16)12-4-5-12/h6-10,12H,4-5,11H2,1-3H3,(H2,21,22)(H,25,27)(H2,23,24,29)	CQAABJLCNKXESD-UHFFFAOYSA-N	50345892	CHEMBL1783709::tert-butyl 4-(3-((3-amino-6-cyclopropylpyrazin-2-yl)methyl)thioureido)phenylcarbamate	MAP kinase-activated protein kinase 2	Homo sapiens		 103							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345892	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345892&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582445	131348823		CHEMBL1783709				ZINC71295552	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644131	CCCc1cnc(N)c(CNC(=S)Nc2ccc3[nH]c(=O)oc3c2)n1	InChI=1S/C16H18N6O2S/c1-2-3-10-7-18-14(17)12(20-10)8-19-15(25)21-9-4-5-11-13(6-9)24-16(23)22-11/h4-7H,2-3,8H2,1H3,(H2,17,18)(H,22,23)(H2,19,21,25)	JYKUXWXQZURHIS-UHFFFAOYSA-N	50345893	1-((3-amino-6-propylpyrazin-2-yl)methyl)-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)thiourea::CHEMBL1783710	MAP kinase-activated protein kinase 2	Homo sapiens		 20							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345893	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345893&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44224183	131348824		CHEMBL1783710				ZINC71294757	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644132	CCCCc1cnc(N)c(CNC(=S)Nc2ccc3[nH]c(=O)oc3c2)n1	InChI=1S/C17H20N6O2S/c1-2-3-4-11-8-19-15(18)13(21-11)9-20-16(26)22-10-5-6-12-14(7-10)25-17(24)23-12/h5-8H,2-4,9H2,1H3,(H2,18,19)(H,23,24)(H2,20,22,26)	AJKKWLMPONETGH-UHFFFAOYSA-N	50345894	1-((3-amino-6-butylpyrazin-2-yl)methyl)-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)thiourea::CHEMBL1783711	MAP kinase-activated protein kinase 2	Homo sapiens		 30							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345894	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345894&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585341	131348825		CHEMBL1783711				ZINC71296155	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644133	Nc1ncc(nc1CNC(=S)Nc1ccc2[nH]c(=O)oc2c1)C1CC1	InChI=1S/C16H16N6O2S/c17-14-12(21-11(6-18-14)8-1-2-8)7-19-15(25)20-9-3-4-10-13(5-9)24-16(23)22-10/h3-6,8H,1-2,7H2,(H2,17,18)(H,22,23)(H2,19,20,25)	HSENOQZMLCILFN-UHFFFAOYSA-N	50345895	1-((3-amino-6-cyclopropylpyrazin-2-yl)methyl)-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)thiourea::CHEMBL1783712	MAP kinase-activated protein kinase 2	Homo sapiens		 15							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345895	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345895&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44224184	131348826		CHEMBL1783712				ZINC71281715	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50644134	CC(C)(C)NC(=O)Nc1ccc(NC(=S)NCc2nc(cnc2N)C2CC2)cc1	InChI=1S/C20H27N7OS/c1-20(2,3)27-18(28)24-13-6-8-14(9-7-13)25-19(29)23-11-16-17(21)22-10-15(26-16)12-4-5-12/h6-10,12H,4-5,11H2,1-3H3,(H2,21,22)(H2,23,25,29)(H2,24,27,28)	AJXBTVULLQQKKY-UHFFFAOYSA-N	50345896	1-(4-(3-((3-amino-6-cyclopropylpyrazin-2-yl)methyl)thioureido)phenyl)-3-tert-butylurea::CHEMBL1783713	MAP kinase-activated protein kinase 2	Homo sapiens		 83							ChEMBL	10.1016/j.bmcl.2009.04.088	10.7270/Q2QZ2B88	19423344			Lin, S; Lombardo, M; Malkani, S; Hale, JJ; Mills, SG; Chapman, K; Thompson, JE; Zhang, WX; Wang, R; Cubbon, RM; O'Neill, EA; Luell, S; Carballo-Jane, E; Yang, L	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50345896	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50345896&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587331	131348827		CHEMBL1783713				ZINC71294848	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50639251	CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2ncc3CCc4c(nn(CCO)c4-c3n2)C(N)=O)c1	InChI=1S/C24H27F3N8O3/c1-33-6-8-34(9-7-33)15-3-5-18(38-24(25,26)27)17(12-15)30-23-29-13-14-2-4-16-20(22(28)37)32-35(10-11-36)21(16)19(14)31-23/h3,5,12-13,36H,2,4,6-11H2,1H3,(H2,28,37)(H,29,30,31)	QHLVBNKYJGBCQJ-UHFFFAOYSA-N	50343559	1-(2-HYDROXYETHYL)-8-[[5-(4-METHYLPIPERAZIN-1-YL)-2-(TRIFLUOROMETHOXY)PHENYL]AMINO]-4,5-DIHYDROPYRIMIDO[5,4-G]INDAZOLE-3-CARBOXAMIDE::1-(2-hydroxyethyl)-8-(5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenylamino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide::CHEMBL1738758	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2011.03.054	10.7270/Q27M088W	21470862			Beria, I; Bossi, RT; Brasca, MG; Caruso, M; Ceccarelli, W; Fachin, G; Fasolini, M; Forte, B; Fiorentini, F; Pesenti, E; Pezzetta, D; Posteri, H; Scolaro, A; Re Depaolini, S; Valsasina, B	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50343559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50343559&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	937	2YAC	49792852	131346495		CHEMBL1738758				ZINC43196885	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641846	Fc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14FN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	XJJYJNMNYDNXNO-UHFFFAOYSA-N	30192	Pyrrolopyridine, 23	MAP kinase-activated protein kinase 2	Homo sapiens				 2700					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30192&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	F10	3FXW,2P3G	11992146	85147952			DB07728			ZINC16052794	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641847	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-10-16(26-19(14)22(11-25-21)4-7-23-8-5-22)15-3-6-24-20(27-15)13-1-2-17-18(9-13)30-12-29-17/h1-3,6,9-10,23,26H,4-5,7-8,11-12H2,(H,25,28)	QSDGMDKMSSYMKU-UHFFFAOYSA-N	50344696	2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1738702	MAP kinase-activated protein kinase 2	Homo sapiens				 620					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344696&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	05B	3R1N,3R2B	53326866	131347632		CHEMBL1738702				ZINC66156777	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641848	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cc2ccccc2o1	InChI=1S/C23H21N5O2/c29-22-15-12-17(27-20(15)23(13-26-22)6-9-24-10-7-23)16-5-8-25-21(28-16)19-11-14-3-1-2-4-18(14)30-19/h1-5,8,11-12,24,27H,6-7,9-10,13H2,(H,26,29)	YIOWMBJTJDJKEK-UHFFFAOYSA-N	50344697	2'-(2-(benzofuran-2-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779352	MAP kinase-activated protein kinase 2	Homo sapiens				 1200					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344697&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246589	131347633		CHEMBL1779352				ZINC71341182	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641849	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(n1)-c1cc2ccccc2o1	InChI=1S/C24H23N5O2/c1-29-10-7-24(8-11-29)14-26-23(30)16-13-18(27-21(16)24)17-6-9-25-22(28-17)20-12-15-4-2-3-5-19(15)31-20/h2-6,9,12-13,27H,7-8,10-11,14H2,1H3,(H,26,30)	SVEWYPKFWQTITP-UHFFFAOYSA-N	50344698	2'-(2-(benzofuran-2-yl)pyrimidin-4-yl)-1-methyl-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779353	MAP kinase-activated protein kinase 2	Homo sapiens				 1600					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344698&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582875	131347634		CHEMBL1779353				ZINC71331758	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641850	CCN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(n1)-c1cc2ccccc2o1	InChI=1S/C25H25N5O2/c1-2-30-11-8-25(9-12-30)15-27-24(31)17-14-19(28-22(17)25)18-7-10-26-23(29-18)21-13-16-5-3-4-6-20(16)32-21/h3-7,10,13-14,28H,2,8-9,11-12,15H2,1H3,(H,27,31)	QJSFMBMLYRDOMB-UHFFFAOYSA-N	50344699	2'-(2-(benzofuran-2-yl)pyrimidin-4-yl)-1-ethyl-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779354	MAP kinase-activated protein kinase 2	Homo sapiens				>10000					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344699&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587800	131347635		CHEMBL1779354				ZINC71334281	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641851	O=C1NCC2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-9-16(26-19(14)22(11-25-21)5-1-6-23-10-22)15-4-7-24-20(27-15)13-2-3-17-18(8-13)30-12-29-17/h2-4,7-9,23,26H,1,5-6,10-12H2,(H,25,28)	UVQZFDXGVAIODZ-UHFFFAOYSA-N	50344700	CHEMBL1779369::rac-2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 930					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344700&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582877	131347636		CHEMBL1779369				ZINC71341216	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641852	COc1cncc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C21H22N6O2/c1-29-14-7-13(9-23-10-14)19-24-6-3-16(27-19)17-8-15-18(26-17)21(12-25-20(15)28)4-2-5-22-11-21/h3,6-10,22,26H,2,4-5,11-12H2,1H3,(H,25,28)	IIJWQBDPICTUBI-UHFFFAOYSA-N	50344701	CHEMBL1779370::rac-2'-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 900					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344701&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585793	131347637		CHEMBL1779370				ZINC71341072	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641853	COCCCOc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H28N6O3/c1-32-10-3-11-33-20-5-4-16(13-27-20)22-26-9-6-18(30-22)19-12-17-21(29-19)24(15-28-23(17)31)7-2-8-25-14-24/h4-6,9,12-13,25,29H,2-3,7-8,10-11,14-15H2,1H3,(H,28,31)	WEUREPGHRFDCFG-UHFFFAOYSA-N	50344702	CHEMBL1779371::rac-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 1400					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344702&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585794	131347638		CHEMBL1779371				ZINC71334049	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641854	O=C1NC[C@@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-9-16(26-19(14)22(11-25-21)5-1-6-23-10-22)15-4-7-24-20(27-15)13-2-3-17-18(8-13)30-12-29-17/h2-4,7-9,23,26H,1,5-6,10-12H2,(H,25,28)/t22-/m0/s1	UVQZFDXGVAIODZ-QFIPXVFZSA-N	50344703	(S)-2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779372	MAP kinase-activated protein kinase 2	Homo sapiens				 500					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344703&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53389527	131347639		CHEMBL1779372					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641855	O=C1NC[C@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-9-16(26-19(14)22(11-25-21)5-1-6-23-10-22)15-4-7-24-20(27-15)13-2-3-17-18(8-13)30-12-29-17/h2-4,7-9,23,26H,1,5-6,10-12H2,(H,25,28)/t22-/m1/s1	UVQZFDXGVAIODZ-JOCHJYFZSA-N	50344704	(R)-2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779373	MAP kinase-activated protein kinase 2	Homo sapiens				 7700					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344704&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584836	131347640		CHEMBL1779373					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641856	COc1cncc(c1)-c1nccc(n1)-c1cc2c([nH]1)[C@]1(CCCNC1)CNC2=O	InChI=1S/C21H22N6O2/c1-29-14-7-13(9-23-10-14)19-24-6-3-16(27-19)17-8-15-18(26-17)21(12-25-20(15)28)4-2-5-22-11-21/h3,6-10,22,26H,2,4-5,11-12H2,1H3,(H,25,28)/t21-/m0/s1	IIJWQBDPICTUBI-NRFANRHFSA-N	50344705	(S)-2'-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779374	MAP kinase-activated protein kinase 2	Homo sapiens				 1100					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344705&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585795	131347641		CHEMBL1779374					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641857	COc1cncc(c1)-c1nccc(n1)-c1cc2c([nH]1)[C@@]1(CCCNC1)CNC2=O	InChI=1S/C21H22N6O2/c1-29-14-7-13(9-23-10-14)19-24-6-3-16(27-19)17-8-15-18(26-17)21(12-25-20(15)28)4-2-5-22-11-21/h3,6-10,22,26H,2,4-5,11-12H2,1H3,(H,25,28)/t21-/m1/s1	IIJWQBDPICTUBI-OAQYLSRUSA-N	50344706	(R)-2'-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779375	MAP kinase-activated protein kinase 2	Homo sapiens				 2300					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344706&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585796	131347642		CHEMBL1779375					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641858	COCCCOc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)[C@]1(CCCNC1)CNC2=O	InChI=1S/C24H28N6O3/c1-32-10-3-11-33-20-5-4-16(13-27-20)22-26-9-6-18(30-22)19-12-17-21(29-19)24(15-28-23(17)31)7-2-8-25-14-24/h4-6,9,12-13,25,29H,2-3,7-8,10-11,14-15H2,1H3,(H,28,31)/t24-/m0/s1	WEUREPGHRFDCFG-DEOSSOPVSA-N	50344707	(S)-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779485	MAP kinase-activated protein kinase 2	Homo sapiens				 400					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344707&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583503	131347643		CHEMBL1779485					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641859	COCCCOc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)[C@@]1(CCCNC1)CNC2=O	InChI=1S/C24H28N6O3/c1-32-10-3-11-33-20-5-4-16(13-27-20)22-26-9-6-18(30-22)19-12-17-21(29-19)24(15-28-23(17)31)7-2-8-25-14-24/h4-6,9,12-13,25,29H,2-3,7-8,10-11,14-15H2,1H3,(H,28,31)/t24-/m1/s1	WEUREPGHRFDCFG-XMMPIXPASA-N	50344708	(R)-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779486	MAP kinase-activated protein kinase 2	Homo sapiens				>10000					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344708&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580533	131347644		CHEMBL1779486					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641860	O=C1NCC2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1	InChI=1S/C20H20N6O/c27-19-14-9-16(25-17(14)20(12-24-19)5-2-7-22-11-20)15-4-8-23-18(26-15)13-3-1-6-21-10-13/h1,3-4,6,8-10,22,25H,2,5,7,11-12H2,(H,24,27)	JCLSXGVSKDLMEO-UHFFFAOYSA-N	50344709	CHEMBL1779487::rac-2'-(2-(pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 2100					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344709&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583504	131347645		CHEMBL1779487				ZINC71333617	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641861	O=C1NC[C@@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1	InChI=1S/C20H20N6O/c27-19-14-9-16(25-17(14)20(12-24-19)5-2-7-22-11-20)15-4-8-23-18(26-15)13-3-1-6-21-10-13/h1,3-4,6,8-10,22,25H,2,5,7,11-12H2,(H,24,27)/t20-/m0/s1	JCLSXGVSKDLMEO-FQEVSTJZSA-N	50344710	(S)-2'-(2-(pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779488	MAP kinase-activated protein kinase 2	Homo sapiens				 1200					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344710&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582533	131347646		CHEMBL1779488					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641862	O=C1NC[C@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1	InChI=1S/C20H20N6O/c27-19-14-9-16(25-17(14)20(12-24-19)5-2-7-22-11-20)15-4-8-23-18(26-15)13-3-1-6-21-10-13/h1,3-4,6,8-10,22,25H,2,5,7,11-12H2,(H,24,27)/t20-/m1/s1	JCLSXGVSKDLMEO-HXUWFJFHSA-N	50344711	(R)-2'-(2-(pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779489	MAP kinase-activated protein kinase 2	Homo sapiens				 5800					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344711&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587411	131347647		CHEMBL1779489					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641863	Fc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14FN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	XJJYJNMNYDNXNO-UHFFFAOYSA-N	30192	Pyrrolopyridine, 23	MAP kinase-activated protein kinase 2	Homo sapiens				 372					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30192&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	F10	3FXW,2P3G	11992146	85147952			DB07728			ZINC16052794	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641864	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-10-16(26-19(14)22(11-25-21)4-7-23-8-5-22)15-3-6-24-20(27-15)13-1-2-17-18(9-13)30-12-29-17/h1-3,6,9-10,23,26H,4-5,7-8,11-12H2,(H,25,28)	QSDGMDKMSSYMKU-UHFFFAOYSA-N	50344696	2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1738702	MAP kinase-activated protein kinase 2	Homo sapiens				 4.3					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344696&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	05B	3R1N,3R2B	53326866	131347632		CHEMBL1738702				ZINC66156777	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641865	O=C1NCC2(CCOCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H20N4O4/c27-21-14-10-16(25-19(14)22(11-24-21)4-7-28-8-5-22)15-3-6-23-20(26-15)13-1-2-17-18(9-13)30-12-29-17/h1-3,6,9-10,25H,4-5,7-8,11-12H2,(H,24,27)	BEQQCXJEJOWVOU-UHFFFAOYSA-N	50344712	2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-2,3,5,5',6,6'-hexahydrospiro[pyran-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779351	MAP kinase-activated protein kinase 2	Homo sapiens				 724					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344712	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344712&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581952	131347648		CHEMBL1779351				ZINC71332844	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641866	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cc2ccccc2o1	InChI=1S/C23H21N5O2/c29-22-15-12-17(27-20(15)23(13-26-22)6-9-24-10-7-23)16-5-8-25-21(28-16)19-11-14-3-1-2-4-18(14)30-19/h1-5,8,11-12,24,27H,6-7,9-10,13H2,(H,26,29)	YIOWMBJTJDJKEK-UHFFFAOYSA-N	50344697	2'-(2-(benzofuran-2-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779352	MAP kinase-activated protein kinase 2	Homo sapiens				 5.9					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344697	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344697&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246589	131347633		CHEMBL1779352				ZINC71341182	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641867	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(n1)-c1cc2ccccc2o1	InChI=1S/C24H23N5O2/c1-29-10-7-24(8-11-29)14-26-23(30)16-13-18(27-21(16)24)17-6-9-25-22(28-17)20-12-15-4-2-3-5-19(15)31-20/h2-6,9,12-13,27H,7-8,10-11,14H2,1H3,(H,26,30)	SVEWYPKFWQTITP-UHFFFAOYSA-N	50344698	2'-(2-(benzofuran-2-yl)pyrimidin-4-yl)-1-methyl-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779353	MAP kinase-activated protein kinase 2	Homo sapiens				 13					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344698	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344698&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582875	131347634		CHEMBL1779353				ZINC71331758	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641868	CCN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(n1)-c1cc2ccccc2o1	InChI=1S/C25H25N5O2/c1-2-30-11-8-25(9-12-30)15-27-24(31)17-14-19(28-22(17)25)18-7-10-26-23(29-18)21-13-16-5-3-4-6-20(16)32-21/h3-7,10,13-14,28H,2,8-9,11-12,15H2,1H3,(H,27,31)	QJSFMBMLYRDOMB-UHFFFAOYSA-N	50344699	2'-(2-(benzofuran-2-yl)pyrimidin-4-yl)-1-ethyl-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779354	MAP kinase-activated protein kinase 2	Homo sapiens				 59					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344699	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344699&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587800	131347635		CHEMBL1779354				ZINC71334281	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641869	CC(=O)c1cccc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C23H23N5O2/c1-14(29)15-3-2-4-16(11-15)21-25-8-5-18(28-21)19-12-17-20(27-19)23(13-26-22(17)30)6-9-24-10-7-23/h2-5,8,11-12,24,27H,6-7,9-10,13H2,1H3,(H,26,30)	PNSAXRDZQXBQNB-UHFFFAOYSA-N	50344713	2'-(2-(3-acetylphenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779355	MAP kinase-activated protein kinase 2	Homo sapiens				 11					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344713	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344713&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583882	131347649		CHEMBL1779355				ZINC71332405	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641870	CC(=O)c1ccc(cc1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C23H23N5O2/c1-14(29)15-2-4-16(5-3-15)21-25-9-6-18(28-21)19-12-17-20(27-19)23(13-26-22(17)30)7-10-24-11-8-23/h2-6,9,12,24,27H,7-8,10-11,13H2,1H3,(H,26,30)	KHRNKTNIGFRANJ-UHFFFAOYSA-N	50344714	2'-(2-(4-acetylphenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779346	MAP kinase-activated protein kinase 2	Homo sapiens				 9.8					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344714	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344714&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246708	131347650		CHEMBL1779346				ZINC71331488	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641871	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCCCOc2c1	InChI=1S/C24H25N5O3/c30-23-16-13-18(28-21(16)24(14-27-23)5-8-25-9-6-24)17-4-7-26-22(29-17)15-2-3-19-20(12-15)32-11-1-10-31-19/h2-4,7,12-13,25,28H,1,5-6,8-11,14H2,(H,27,30)	FQYJPJCURIYLNH-UHFFFAOYSA-N	50344715	2'-(2-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779347	MAP kinase-activated protein kinase 2	Homo sapiens				 10					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344715	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344715&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583881	131347651		CHEMBL1779347				ZINC71341220	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641872	CC(C)c1cccc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C24H27N5O/c1-15(2)16-4-3-5-17(12-16)22-26-9-6-19(29-22)20-13-18-21(28-20)24(14-27-23(18)30)7-10-25-11-8-24/h3-6,9,12-13,15,25,28H,7-8,10-11,14H2,1-2H3,(H,27,30)	HEJHXDYULVMEKQ-UHFFFAOYSA-N	50344716	2'-(2-(3-isopropylphenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779348	MAP kinase-activated protein kinase 2	Homo sapiens				 112					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344716	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344716&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246828	131347652		CHEMBL1779348				ZINC71335007	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641873	Fc1ccccc1-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C21H20FN5O/c22-15-4-2-1-3-13(15)19-24-8-5-16(27-19)17-11-14-18(26-17)21(12-25-20(14)28)6-9-23-10-7-21/h1-5,8,11,23,26H,6-7,9-10,12H2,(H,25,28)	REBLJHSDQODSAN-UHFFFAOYSA-N	50344717	2'-(2-(2-fluorophenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779349	MAP kinase-activated protein kinase 2	Homo sapiens				 29					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344717	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344717&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246706	131347653		CHEMBL1779349				ZINC71333933	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641874	Fc1cccc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C21H20FN5O/c22-14-3-1-2-13(10-14)19-24-7-4-16(27-19)17-11-15-18(26-17)21(12-25-20(15)28)5-8-23-9-6-21/h1-4,7,10-11,23,26H,5-6,8-9,12H2,(H,25,28)	HSTAZHAJDWPDQD-UHFFFAOYSA-N	50344718	2'-(2-(3-fluorophenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779350	MAP kinase-activated protein kinase 2	Homo sapiens				 8.3					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344718	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344718&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246707	131347654		CHEMBL1779350				ZINC71333222	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641875	FC(F)(F)c1cccc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C22H20F3N5O/c23-22(24,25)14-3-1-2-13(10-14)19-27-7-4-16(30-19)17-11-15-18(29-17)21(12-28-20(15)31)5-8-26-9-6-21/h1-4,7,10-11,26,29H,5-6,8-9,12H2,(H,28,31)	UJPFVKSGRMCATN-UHFFFAOYSA-N	50344719	2'-(2-(3-(trifluoromethyl)phenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779356	MAP kinase-activated protein kinase 2	Homo sapiens				 15					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344719	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344719&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246955	131347655		CHEMBL1779356				ZINC71332550	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641876	FC(F)(F)c1ccc(cc1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C22H20F3N5O/c23-22(24,25)14-3-1-13(2-4-14)19-27-8-5-16(30-19)17-11-15-18(29-17)21(12-28-20(15)31)6-9-26-10-7-21/h1-5,8,11,26,29H,6-7,9-10,12H2,(H,28,31)	GVVFBBCDUKYDOI-UHFFFAOYSA-N	50344720	2'-(2-(4-(trifluoromethyl)phenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779357	MAP kinase-activated protein kinase 2	Homo sapiens				 6.9					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344720	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344720&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53246831	131347656		CHEMBL1779357				ZINC71341330	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641877	CC(C)(C)c1ccc(cc1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C25H29N5O/c1-24(2,3)17-6-4-16(5-7-17)22-27-11-8-19(30-22)20-14-18-21(29-20)25(15-28-23(18)31)9-12-26-13-10-25/h4-8,11,14,26,29H,9-10,12-13,15H2,1-3H3,(H,28,31)	NNTBWLJXCUKFPB-UHFFFAOYSA-N	50344721	2'-(2-(4-tert-butylphenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779358	MAP kinase-activated protein kinase 2	Homo sapiens				 6.2					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344721	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344721&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587801	131347657		CHEMBL1779358				ZINC71341196	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641878	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2ccccc2c1	InChI=1S/C25H23N5O/c31-24-19-14-21(29-22(19)25(15-28-24)8-11-26-12-9-25)20-7-10-27-23(30-20)18-6-5-16-3-1-2-4-17(16)13-18/h1-7,10,13-14,26,29H,8-9,11-12,15H2,(H,28,31)	YZAILENMJOUFMG-UHFFFAOYSA-N	50344722	2'-(2-(naphthalen-2-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779359	MAP kinase-activated protein kinase 2	Homo sapiens				 5.1					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344722	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344722&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581953	131347658		CHEMBL1779359				ZINC71333282	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641879	Clc1cc(Cl)cc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C21H19Cl2N5O/c22-13-7-12(8-14(23)9-13)19-25-4-1-16(28-19)17-10-15-18(27-17)21(11-26-20(15)29)2-5-24-6-3-21/h1,4,7-10,24,27H,2-3,5-6,11H2,(H,26,29)	YOQPANSJZKFLMM-UHFFFAOYSA-N	50344723	2'-(2-(3,5-dichlorophenyl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779360	MAP kinase-activated protein kinase 2	Homo sapiens				 4.5					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344723	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344723&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580895	131347659		CHEMBL1779360				ZINC71331889	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641880	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cnc2ccccc2c1	InChI=1S/C24H22N6O/c31-23-17-12-20(29-21(17)24(14-28-23)6-9-25-10-7-24)19-5-8-26-22(30-19)16-11-15-3-1-2-4-18(15)27-13-16/h1-5,8,11-13,25,29H,6-7,9-10,14H2,(H,28,31)	MVYSDVQLMDMXOP-UHFFFAOYSA-N	50344724	2'-(2-(quinolin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779361	MAP kinase-activated protein kinase 2	Homo sapiens				 6.3					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344724&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587802	131347660		CHEMBL1779361				ZINC71333600	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641881	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1	InChI=1S/C20H20N6O/c27-19-14-10-16(25-17(14)20(12-24-19)4-8-21-9-5-20)15-3-7-23-18(26-15)13-2-1-6-22-11-13/h1-3,6-7,10-11,21,25H,4-5,8-9,12H2,(H,24,27)	NDVQWFQPWFFHJY-UHFFFAOYSA-N	50344725	2'-(2-(pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779362	MAP kinase-activated protein kinase 2	Homo sapiens				 1.1					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344725	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344725&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580896	131347661		CHEMBL1779362				ZINC71332063	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641882	COc1cncc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C21H22N6O2/c1-29-14-8-13(10-23-11-14)19-24-5-2-16(27-19)17-9-15-18(26-17)21(12-25-20(15)28)3-6-22-7-4-21/h2,5,8-11,22,26H,3-4,6-7,12H2,1H3,(H,25,28)	LRQYWJHBWMMKCY-UHFFFAOYSA-N	50344726	2'-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779363	MAP kinase-activated protein kinase 2	Homo sapiens				 6.9					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344726	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344726&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582876	131347662		CHEMBL1779363				ZINC71334947	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641883	Nc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C20H21N7O/c21-16-2-1-12(10-24-16)18-23-6-3-14(27-18)15-9-13-17(26-15)20(11-25-19(13)28)4-7-22-8-5-20/h1-3,6,9-10,22,26H,4-5,7-8,11H2,(H2,21,24)(H,25,28)	PHJUBBLFCVIXDC-UHFFFAOYSA-N	50344727	2'-(2-(6-aminopyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779364	MAP kinase-activated protein kinase 2	Homo sapiens				 15					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344727	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344727&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585792	131347663		CHEMBL1779364				ZINC71340928	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641884	CCC(=O)Nc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C23H25N7O2/c1-2-19(31)30-18-4-3-14(12-26-18)21-25-8-5-16(29-21)17-11-15-20(28-17)23(13-27-22(15)32)6-9-24-10-7-23/h3-5,8,11-12,24,28H,2,6-7,9-10,13H2,1H3,(H,27,32)(H,26,30,31)	IDUCVMPPUQEZII-UHFFFAOYSA-N	50344728	CHEMBL1779365::N-(5-(4-(4'-oxo-1',4',5',6'-tetrahydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridine]-2'-yl)pyrimidin-2-yl)pyridin-2-yl)propionamide	MAP kinase-activated protein kinase 2	Homo sapiens				 3.6					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344728&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54581954	131347664		CHEMBL1779365				ZINC71332763	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641885	Nc1ncc(cn1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C19H20N8O/c20-18-23-8-11(9-24-18)16-22-4-1-13(27-16)14-7-12-15(26-14)19(10-25-17(12)28)2-5-21-6-3-19/h1,4,7-9,21,26H,2-3,5-6,10H2,(H,25,28)(H2,20,23,24)	UEEGPWPCUKOTQB-UHFFFAOYSA-N	50344729	2'-(2'-amino-2,5'-bipyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779366	MAP kinase-activated protein kinase 2	Homo sapiens				 2.1					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344729	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344729&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53235515	131347665		CHEMBL1779366				ZINC71332855	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641886	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cnc(NC2CCCC2)nc1	InChI=1S/C24H28N8O/c33-22-17-11-19(31-20(17)24(14-29-22)6-9-25-10-7-24)18-5-8-26-21(32-18)15-12-27-23(28-13-15)30-16-3-1-2-4-16/h5,8,11-13,16,25,31H,1-4,6-7,9-10,14H2,(H,29,33)(H,27,28,30)	PAKKBWJNHBQVIH-UHFFFAOYSA-N	50344730	2'-(2'-(cyclopentylamino)-2,5'-bipyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779367	MAP kinase-activated protein kinase 2	Homo sapiens				 1.7					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344730	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344730&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54586772	131347666		CHEMBL1779367				ZINC71340545	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641887	O=C1NCC2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cc2ccccc2o1	InChI=1S/C23H21N5O2/c29-22-15-11-17(27-20(15)23(13-26-22)7-3-8-24-12-23)16-6-9-25-21(28-16)19-10-14-4-1-2-5-18(14)30-19/h1-2,4-6,9-11,24,27H,3,7-8,12-13H2,(H,26,29)	ALNWXNDKZNZXRC-UHFFFAOYSA-N	50344731	CHEMBL1779368::rac-2'-(2-(benzofuran-2-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 11					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344731	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344731&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580897	131347667		CHEMBL1779368				ZINC71341374	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641888	O=C1NCC2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-9-16(26-19(14)22(11-25-21)5-1-6-23-10-22)15-4-7-24-20(27-15)13-2-3-17-18(8-13)30-12-29-17/h2-4,7-9,23,26H,1,5-6,10-12H2,(H,25,28)	UVQZFDXGVAIODZ-UHFFFAOYSA-N	50344700	CHEMBL1779369::rac-2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 28					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344700	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344700&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582877	131347636		CHEMBL1779369				ZINC71341216	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641889	COc1cncc(c1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C21H22N6O2/c1-29-14-7-13(9-23-10-14)19-24-6-3-16(27-19)17-8-15-18(26-17)21(12-25-20(15)28)4-2-5-22-11-21/h3,6-10,22,26H,2,4-5,11-12H2,1H3,(H,25,28)	IIJWQBDPICTUBI-UHFFFAOYSA-N	50344701	CHEMBL1779370::rac-2'-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 24					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344701	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344701&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585793	131347637		CHEMBL1779370				ZINC71341072	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641890	COCCCOc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H28N6O3/c1-32-10-3-11-33-20-5-4-16(13-27-20)22-26-9-6-18(30-22)19-12-17-21(29-19)24(15-28-23(17)31)7-2-8-25-14-24/h4-6,9,12-13,25,29H,2-3,7-8,10-11,14-15H2,1H3,(H,28,31)	WEUREPGHRFDCFG-UHFFFAOYSA-N	50344702	CHEMBL1779371::rac-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 21					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344702	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344702&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585794	131347638		CHEMBL1779371				ZINC71334049	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641891	O=C1NC[C@@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-9-16(26-19(14)22(11-25-21)5-1-6-23-10-22)15-4-7-24-20(27-15)13-2-3-17-18(8-13)30-12-29-17/h2-4,7-9,23,26H,1,5-6,10-12H2,(H,25,28)/t22-/m0/s1	UVQZFDXGVAIODZ-QFIPXVFZSA-N	50344703	(S)-2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779372	MAP kinase-activated protein kinase 2	Homo sapiens				 7.4					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344703	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344703&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53389527	131347639		CHEMBL1779372					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641892	O=C1NC[C@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-9-16(26-19(14)22(11-25-21)5-1-6-23-10-22)15-4-7-24-20(27-15)13-2-3-17-18(8-13)30-12-29-17/h2-4,7-9,23,26H,1,5-6,10-12H2,(H,25,28)/t22-/m1/s1	UVQZFDXGVAIODZ-JOCHJYFZSA-N	50344704	(R)-2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779373	MAP kinase-activated protein kinase 2	Homo sapiens				 91					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344704	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344704&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54584836	131347640		CHEMBL1779373					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641893	COc1cncc(c1)-c1nccc(n1)-c1cc2c([nH]1)[C@]1(CCCNC1)CNC2=O	InChI=1S/C21H22N6O2/c1-29-14-7-13(9-23-10-14)19-24-6-3-16(27-19)17-8-15-18(26-17)21(12-25-20(15)28)4-2-5-22-11-21/h3,6-10,22,26H,2,4-5,11-12H2,1H3,(H,25,28)/t21-/m0/s1	IIJWQBDPICTUBI-NRFANRHFSA-N	50344705	(S)-2'-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779374	MAP kinase-activated protein kinase 2	Homo sapiens				 9.3					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344705	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344705&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585795	131347641		CHEMBL1779374					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641894	COc1cncc(c1)-c1nccc(n1)-c1cc2c([nH]1)[C@@]1(CCCNC1)CNC2=O	InChI=1S/C21H22N6O2/c1-29-14-7-13(9-23-10-14)19-24-6-3-16(27-19)17-8-15-18(26-17)21(12-25-20(15)28)4-2-5-22-11-21/h3,6-10,22,26H,2,4-5,11-12H2,1H3,(H,25,28)/t21-/m1/s1	IIJWQBDPICTUBI-OAQYLSRUSA-N	50344706	(R)-2'-(2-(5-methoxypyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779375	MAP kinase-activated protein kinase 2	Homo sapiens				 126					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344706	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344706&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54585796	131347642		CHEMBL1779375					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641895	COCCCOc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)[C@]1(CCCNC1)CNC2=O	InChI=1S/C24H28N6O3/c1-32-10-3-11-33-20-5-4-16(13-27-20)22-26-9-6-18(30-22)19-12-17-21(29-19)24(15-28-23(17)31)7-2-8-25-14-24/h4-6,9,12-13,25,29H,2-3,7-8,10-11,14-15H2,1H3,(H,28,31)/t24-/m0/s1	WEUREPGHRFDCFG-DEOSSOPVSA-N	50344707	(S)-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779485	MAP kinase-activated protein kinase 2	Homo sapiens				 6.9					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344707	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344707&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583503	131347643		CHEMBL1779485					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641896	COCCCOc1ccc(cn1)-c1nccc(n1)-c1cc2c([nH]1)[C@@]1(CCCNC1)CNC2=O	InChI=1S/C24H28N6O3/c1-32-10-3-11-33-20-5-4-16(13-27-20)22-26-9-6-18(30-22)19-12-17-21(29-19)24(15-28-23(17)31)7-2-8-25-14-24/h4-6,9,12-13,25,29H,2-3,7-8,10-11,14-15H2,1H3,(H,28,31)/t24-/m1/s1	WEUREPGHRFDCFG-XMMPIXPASA-N	50344708	(R)-2'-(2-(6-(3-methoxypropoxy)pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779486	MAP kinase-activated protein kinase 2	Homo sapiens				 129					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344708	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344708&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580533	131347644		CHEMBL1779486					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641897	O=C1NCC2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1	InChI=1S/C20H20N6O/c27-19-14-9-16(25-17(14)20(12-24-19)5-2-7-22-11-20)15-4-8-23-18(26-15)13-3-1-6-21-10-13/h1,3-4,6,8-10,22,25H,2,5,7,11-12H2,(H,24,27)	JCLSXGVSKDLMEO-UHFFFAOYSA-N	50344709	CHEMBL1779487::rac-2'-(2-(pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one	MAP kinase-activated protein kinase 2	Homo sapiens				 18					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344709&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54583504	131347645		CHEMBL1779487				ZINC71333617	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641898	O=C1NC[C@@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1	InChI=1S/C20H20N6O/c27-19-14-9-16(25-17(14)20(12-24-19)5-2-7-22-11-20)15-4-8-23-18(26-15)13-3-1-6-21-10-13/h1,3-4,6,8-10,22,25H,2,5,7,11-12H2,(H,24,27)/t20-/m0/s1	JCLSXGVSKDLMEO-FQEVSTJZSA-N	50344710	(S)-2'-(2-(pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779488	MAP kinase-activated protein kinase 2	Homo sapiens				 6.5					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344710&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582533	131347646		CHEMBL1779488					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641899	O=C1NC[C@]2(CCCNC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cccnc1	InChI=1S/C20H20N6O/c27-19-14-9-16(25-17(14)20(12-24-19)5-2-7-22-11-20)15-4-8-23-18(26-15)13-3-1-6-21-10-13/h1,3-4,6,8-10,22,25H,2,5,7,11-12H2,(H,24,27)/t20-/m1/s1	JCLSXGVSKDLMEO-HXUWFJFHSA-N	50344711	(R)-2'-(2-(pyridin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-3,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779489	MAP kinase-activated protein kinase 2	Homo sapiens				 288					ChEMBL	10.1016/j.bmcl.2011.04.016	10.7270/Q2FT8MCB	21565498			Kaptein, A; Oubrie, A; de Zwart, E; Hoogenboom, N; de Wit, J; van de Kar, B; van Hoek, M; Vogel, G; de Kimpe, V; Schultz-Fademrecht, C; Borsboom, J; van Zeeland, M; Versteegh, J; Kazemier, B; de Roos, J; Wijnands, F; Dulos, J; Jaeger, M; Leandro-Garcia, P; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344711	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344711&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587411	131347647		CHEMBL1779489					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641932	O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cnc2ccccc2c1	InChI=1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)	OWFLADWRSCINST-UHFFFAOYSA-N	30185	CHEMBL226403::Pyrrolopyridine, 16	MAP kinase-activated protein kinase 2	Homo sapiens				 49					ChEMBL	10.1016/j.bmcl.2011.04.018	10.7270/Q26973W4	21565500			Barf, T; Kaptein, A; de Wilde, S; van der Heijden, R; van Someren, R; Demont, D; Schultz-Fademrecht, C; Versteegh, J; van Zeeland, M; Seegers, N; Kazemier, B; van de Kar, B; van Hoek, M; de Roos, J; Klop, H; Smeets, R; Hofstra, C; Hornberg, J; Oubrie, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30185	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30185&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P4O	2JBP,3GOK,3FHR,2JBO,3R2Y,7NRB	10389239	85147945		CHEMBL226403	DB08358			ZINC16052855	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641933	NCCn1nc(cc1C(O)=O)-c1ccnc(c1)-c1cnc2ccccc2c1	InChI=1S/C20H17N5O2/c21-6-8-25-19(20(26)27)11-18(24-25)14-5-7-22-17(10-14)15-9-13-3-1-2-4-16(13)23-12-15/h1-5,7,9-12H,6,8,21H2,(H,26,27)	IDPLDWUOSVSMNS-UHFFFAOYSA-N	50344749	1-(2-aminoethyl)-3-(2-(quinolin-3-yl)pyridin-4-yl)-1H-pyrazole-5-carboxylic acid::1-(2-aminoethyl)-3-[2-(quinolin-3-yl)pyridin-4-yl]-1H-pyrazole-5-carboxylic acid::CHEMBL1738780	MAP kinase-activated protein kinase 2	Homo sapiens				 28					ChEMBL	10.1016/j.bmcl.2011.04.018	10.7270/Q26973W4	21565500			Barf, T; Kaptein, A; de Wilde, S; van der Heijden, R; van Someren, R; Demont, D; Schultz-Fademrecht, C; Versteegh, J; van Zeeland, M; Seegers, N; Kazemier, B; van de Kar, B; van Hoek, M; de Roos, J; Klop, H; Smeets, R; Hofstra, C; Hornberg, J; Oubrie, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344749	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344749&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	CD2	3R30	9826115	131347685		CHEMBL1738780				ZINC03962029	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641934	O=C1NCC2(CCCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cnc2ccccc2c1	InChI=1S/C24H21N5O/c30-23-17-12-20(28-21(17)24(14-27-23)8-3-4-9-24)19-7-10-25-22(29-19)16-11-15-5-1-2-6-18(15)26-13-16/h1-2,5-7,10-13,28H,3-4,8-9,14H2,(H,27,30)	QQKYFJMFTLSOKW-UHFFFAOYSA-N	50344750	2'-(2-(quinolin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[cyclopentane-1,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779516	MAP kinase-activated protein kinase 2	Homo sapiens				 234					ChEMBL	10.1016/j.bmcl.2011.04.018	10.7270/Q26973W4	21565500			Barf, T; Kaptein, A; de Wilde, S; van der Heijden, R; van Someren, R; Demont, D; Schultz-Fademrecht, C; Versteegh, J; van Zeeland, M; Seegers, N; Kazemier, B; van de Kar, B; van Hoek, M; de Roos, J; Klop, H; Smeets, R; Hofstra, C; Hornberg, J; Oubrie, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344750&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54580537	131347686		CHEMBL1779516				ZINC71335104	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641935	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1cnc2ccccc2c1	InChI=1S/C24H22N6O/c31-23-17-12-20(29-21(17)24(14-28-23)6-9-25-10-7-24)19-5-8-26-22(30-19)16-11-15-3-1-2-4-18(15)27-13-16/h1-5,8,11-13,25,29H,6-7,9-10,14H2,(H,28,31)	MVYSDVQLMDMXOP-UHFFFAOYSA-N	50344724	2'-(2-(quinolin-3-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1779361	MAP kinase-activated protein kinase 2	Homo sapiens				 6					ChEMBL	10.1016/j.bmcl.2011.04.018	10.7270/Q26973W4	21565500			Barf, T; Kaptein, A; de Wilde, S; van der Heijden, R; van Someren, R; Demont, D; Schultz-Fademrecht, C; Versteegh, J; van Zeeland, M; Seegers, N; Kazemier, B; van de Kar, B; van Hoek, M; de Roos, J; Klop, H; Smeets, R; Hofstra, C; Hornberg, J; Oubrie, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344724	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344724&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54587802	131347660		CHEMBL1779361				ZINC71333600	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641936	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-10-16(26-19(14)22(11-25-21)4-7-23-8-5-22)15-3-6-24-20(27-15)13-1-2-17-18(9-13)30-12-29-17/h1-3,6,9-10,23,26H,4-5,7-8,11-12H2,(H,25,28)	QSDGMDKMSSYMKU-UHFFFAOYSA-N	50344696	2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1738702	MAP kinase-activated protein kinase 2	Homo sapiens				 4					ChEMBL	10.1016/j.bmcl.2011.04.018	10.7270/Q26973W4	21565500			Barf, T; Kaptein, A; de Wilde, S; van der Heijden, R; van Someren, R; Demont, D; Schultz-Fademrecht, C; Versteegh, J; van Zeeland, M; Seegers, N; Kazemier, B; van de Kar, B; van Hoek, M; de Roos, J; Klop, H; Smeets, R; Hofstra, C; Hornberg, J; Oubrie, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344696&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	05B	3R1N,3R2B	53326866	131347632		CHEMBL1738702				ZINC66156777	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641937	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-10-16(26-19(14)22(11-25-21)4-7-23-8-5-22)15-3-6-24-20(27-15)13-1-2-17-18(9-13)30-12-29-17/h1-3,6,9-10,23,26H,4-5,7-8,11-12H2,(H,25,28)	QSDGMDKMSSYMKU-UHFFFAOYSA-N	50344696	2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1738702	MAP kinase-activated protein kinase 2	Homo sapiens				 620					ChEMBL	10.1016/j.bmcl.2011.04.018	10.7270/Q26973W4	21565500			Barf, T; Kaptein, A; de Wilde, S; van der Heijden, R; van Someren, R; Demont, D; Schultz-Fademrecht, C; Versteegh, J; van Zeeland, M; Seegers, N; Kazemier, B; van de Kar, B; van Hoek, M; de Roos, J; Klop, H; Smeets, R; Hofstra, C; Hornberg, J; Oubrie, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344696&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	05B	3R1N,3R2B	53326866	131347632		CHEMBL1738702				ZINC66156777	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50641938	NCC1CNC(=O)c2cc(nn12)-c1ccnc(c1)-c1cnc2ccccc2c1	InChI=1S/C21H18N6O/c22-10-16-12-25-21(28)20-9-19(26-27(16)20)14-5-6-23-18(8-14)15-7-13-3-1-2-4-17(13)24-11-15/h1-9,11,16H,10,12,22H2,(H,25,28)	ZAVPLUDVERDQKO-UHFFFAOYSA-N	50344751	7-(aminomethyl)-2-(2-(quinolin-3-yl)pyridin-4-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one::CHEMBL1779517	MAP kinase-activated protein kinase 2	Homo sapiens				 151					ChEMBL	10.1016/j.bmcl.2011.04.018	10.7270/Q26973W4	21565500			Barf, T; Kaptein, A; de Wilde, S; van der Heijden, R; van Someren, R; Demont, D; Schultz-Fademrecht, C; Versteegh, J; van Zeeland, M; Seegers, N; Kazemier, B; van de Kar, B; van Hoek, M; de Roos, J; Klop, H; Smeets, R; Hofstra, C; Hornberg, J; Oubrie, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344751&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			54582534	131347687		CHEMBL1779517				ZINC71333263	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50668170	CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21	InChI=1S/C28H28N4O3/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34)/t18-/m0/s1	ZCBUQCWBWNUWSU-SFHVURJKSA-N	17055	(18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^{7,14}.0^{2,6}.0^{8,13}.0^{22,27}]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione::(9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-di(metheno)dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione::K00587a::LY 333531::LY-333531::LY333531::Ruboxistaurin::cid_153999	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17055&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	LY4	2J2I,1UU3	153999	46517285				5263		ZINC03812168	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50665631	CCN1CCN(CC1)c1ccc(Nc2cc(ncn2)N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)cc1	InChI=1S/C26H31Cl2N7O3/c1-5-34-10-12-35(13-11-34)18-8-6-17(7-9-18)31-21-15-22(30-16-29-21)33(2)26(36)32-25-23(27)19(37-3)14-20(38-4)24(25)28/h6-9,14-16H,5,10-13H2,1-4H3,(H,32,36)(H,29,30,31)	QADPYRIHXKWUSV-UHFFFAOYSA-N	50355393	BGJ398::CHEMBL1834657::US9434697, BGJ398::US9730931, BGJ398	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm2006222	10.7270/Q22N52N1	21936542			Guagnano, V; Furet, P; Spanka, C; Bordas, V; Le Douget, M; Stamm, C; Brueggen, J; Jensen, MR; Schnell, C; Schmid, H; Wartmann, M; Berghausen, J; Drueckes, P; Zimmerlin, A; Bussiere, D; Murray, J; Graus Porta, D	Novartis Institute for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355393&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	07J	3TT0	53235510	136362079		CHEMBL1834657				ZINC72105034	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50668340	Cn1cc(cn1)-c1ccc2nnc(Sc3ccc4ncccc4c3)n2n1	InChI=1S/C18H13N7S/c1-24-11-13(10-20-24)16-6-7-17-21-22-18(25(17)23-16)26-14-4-5-15-12(9-14)3-2-8-19-15/h2-11H,1H3	BCZUAADEACICHN-UHFFFAOYSA-N	60589	6-{[6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl]sulfanyl}quinoline (4)::BDBM50355498	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60589	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60589&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	SX8	3DKF,3DKG	16187854	24782328			DB08584			ZINC15962404	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50668421	CC[C@H]1N(C2CCCC2)c2nc(Nc3ccc(cc3OC)C(=O)NC3CCN(C)CC3)ncc2N(C)C1=O	InChI=1S/C28H39N7O3/c1-5-22-27(37)34(3)23-17-29-28(32-25(23)35(22)20-8-6-7-9-20)31-21-11-10-18(16-24(21)38-4)26(36)30-19-12-14-33(2)15-13-19/h10-11,16-17,19-20,22H,5-9,12-15H2,1-4H3,(H,30,36)(H,29,31,32)/t22-/m1/s1	XQVVPGYIWAGRNI-JOCHJYFZSA-N	25121	4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,7,8-tetrahydropteridin-2-yl]amino}-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide::BI 2536::CHEMBL513909::US10450297, Example 300::US8598172, 5	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25121&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	R78	4OGI,6MF9,6BQQ,7K0U,2RKU,6CW0,7LAI,4O74,4PY6,4I5M,5TCM,5C8G,5VBQ,7L9G,7L9L,7N7M	11364421	56374263		CHEMBL513909		5666		ZINC13986815	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50652957	CN1CCN(CC1)c1ccc(cc1)-c1cc2n(C)nc(N)c2c(=O)[nH]1	InChI=1S/C18H22N6O/c1-22-7-9-24(10-8-22)13-5-3-12(4-6-13)14-11-15-16(18(25)20-14)17(19)21-23(15)2/h3-6,11H,7-10H2,1-2H3,(H2,19,21)(H,20,25)	VLEQHZKBZRDDGS-UHFFFAOYSA-N	50349877	CHEMBL1813625	MAP kinase-activated protein kinase 2	Homo sapiens		 35000							ChEMBL	10.1016/j.bmc.2011.03.069	10.7270/Q22807ZF	21536449			Smyth, LA; Matthews, TP; Collins, I	The Institute of Cancer Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50349877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50349877&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53249000	136356563		CHEMBL1813625				ZINC72112297	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50666158	Cc1cnc(Nc2ccc(OCCN3CCCC3)cc2)nc1Nc1cccc(c1)S(=O)(=O)NC(C)(C)C	InChI=1S/C27H36N6O3S/c1-20-19-28-26(30-21-10-12-23(13-11-21)36-17-16-33-14-5-6-15-33)31-25(20)29-22-8-7-9-24(18-22)37(34,35)32-27(2,3)4/h7-13,18-19,32H,5-6,14-17H2,1-4H3,(H2,28,29,30,31)	JOOXLOJCABQBSG-UHFFFAOYSA-N	50332294	CHEMBL1287853::N-tert-butyl-3-(5-methyl-2-(4-(2-(pyrrolidin-1-yl)ethoxy)phenylamino)pyrimidin-4-ylamino)benzenesulfonamide::US10112907, Example 00018::US10730860, TABLE 1.3::US10766894, Compound TABLE 1.3::US11203595, TABLE 1.3::US11384069, Example T-5	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50332294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50332294&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	2TA	4OGJ,4PS5,6VNE	16722836	123111409		CHEMBL1287853		5716		ZINC19862646	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50650757	Cc1c(cn2ncnc(Nc3cc(ccc3C)C(=O)NC3CC3)c12)C(=O)c1ccccc1	InChI=1S/C25H23N5O2/c1-15-8-9-18(25(32)28-19-10-11-19)12-21(15)29-24-22-16(2)20(13-30(22)27-14-26-24)23(31)17-6-4-3-5-7-17/h3-9,12-14,19H,10-11H2,1-2H3,(H,28,32)(H,26,27,29)	CQPNJQRTSADQCI-UHFFFAOYSA-N	50348880	CHEMBL1807446	MAP kinase-activated protein kinase 2	Homo sapiens		>25000							ChEMBL	10.1016/j.bmcl.2011.05.091	10.7270/Q2WS8TMN	21705217			Dyckman, AJ; Li, T; Pitt, S; Zhang, R; Shen, DR; McIntyre, KW; Gillooly, KM; Shuster, DJ; Doweyko, AM; Sack, JS; Kish, K; Kiefer, SE; Newitt, JA; Zhang, H; Marathe, PH; McKinnon, M; Barrish, JC; Dodd, JH; Schieven, GL; Leftheris, K	Bristol-Myers Squibb Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348880&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	NK0	3S4Q	10048045	136355566		CHEMBL1807446				ZINC68245532	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50667751	CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl	InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1	BIIVYFLTOXDAOV-YVEFUNNKSA-N	5655	2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one::CHEMBL428690::Flavopiridol::US10294218, Example Flavopiridol::US9617225, Flavopiridol	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5655&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	CPB	1C8K,1E1Y,3BLR,3EBP,4O71	5287969	8035270		CHEMBL428690	DB03496	5680		ZINC21288966	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50669154	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1	InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	MLDQJTXFUGDVEO-UHFFFAOYSA-N	16673	4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide::4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-picolinamide;tosylic acid::BAY 43-9006::BAY 439006::BAY439006::CHEMBL1336::Hit compound, 8::Nexavar::Sorafenib::Sorafenib, 4::US10183928, Sorafenib::US10202365, Compound Sorafenib::US10227329, Compound Sorafenib::US10584114, Compound Sorafenib::US10774070, Compound Sorafenib::US10980809, Example Sorafenib::US11279688, Compound Sorafenib::US11505527, Compound Sorafenib::US9029401, Sorafenib::US9469639, Sorafenib::US9902709, Comparative example 1::Xarelto::cid_216239	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16673&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	BAX	3GCS,4ASD,3WZE,5HI2,3HEG,1UWH,1UWJ,3RGF	216239	46516901	50924	CHEMBL1336	DB00398	5711		ZINC01493878	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649709	COCCOc1cncc(c1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C22H22N4O3/c1-28-6-7-29-15-8-14(10-23-12-15)19-9-17-13(11-25-19)2-3-16-20-18(26-21(16)17)4-5-24-22(20)27/h8-12,26H,2-7H2,1H3,(H,24,27)	LVZFXQCXIOECDX-UHFFFAOYSA-N	50348479	CHEMBL1801195	MAP kinase-activated protein kinase 2	Homo sapiens		 1700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348479&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673312	136355165		CHEMBL1801195				ZINC72109815	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649710	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3n(C)c21)-c1ccccc1F	InChI=1S/C24H23FN4O/c1-28-12-24(13-28)11-27-23(30)20-16-8-7-14-10-26-19(15-5-3-4-6-18(15)25)9-17(14)21(16)29(2)22(20)24/h3-6,9-10H,7-8,11-13H2,1-2H3,(H,27,30)	RWHHQGYUDHQGSP-UHFFFAOYSA-N	50348480	CHEMBL1801312	MAP kinase-activated protein kinase 2	Homo sapiens		 1700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659481	136355166		CHEMBL1801312				ZINC72141130	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649711	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(nc4-c3[nH]c21)-c1ccc(F)nc1	InChI=1S/C21H19FN6O/c1-28-9-21(10-28)8-25-20(29)15-13-4-2-11-6-24-19(12-3-5-14(22)23-7-12)27-16(11)17(13)26-18(15)21/h3,5-7,26H,2,4,8-10H2,1H3,(H,25,29)	WPSLEAFBLLIBPF-UHFFFAOYSA-N	50348481	CHEMBL1801307	MAP kinase-activated protein kinase 2	Homo sapiens		 1800							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348481&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679979	136355167		CHEMBL1801307				ZINC72109881	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649712	COc1ccc(cc1)-c1ncc2CCc3c([nH]c4CC5(CC5)NC(=O)c34)-c2n1	InChI=1S/C22H20N4O2/c1-28-14-5-2-12(3-6-14)20-23-11-13-4-7-15-17-16(24-19(15)18(13)25-20)10-22(8-9-22)26-21(17)27/h2-3,5-6,11,24H,4,7-10H2,1H3,(H,26,27)	NGTDZYCIPFIDGW-UHFFFAOYSA-N	50348482	CHEMBL1801299	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348482&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673317	136355168		CHEMBL1801299				ZINC72108945	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649713	Fc1ccccc1-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C20H16FN3O/c21-15-4-2-1-3-12(15)17-9-14-11(10-23-17)5-6-13-18-16(24-19(13)14)7-8-22-20(18)25/h1-4,9-10,24H,5-8H2,(H,22,25)	BKXIFWPZQGIBQU-UHFFFAOYSA-N	50348483	CHEMBL1801194	MAP kinase-activated protein kinase 2	Homo sapiens		 2700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348483&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676644	136355169		CHEMBL1801194				ZINC72108987	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649714	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(nc4-c3[nH]c21)-c1ccc(OCCN2CCOCC2)cc1	InChI=1S/C28H32N6O3/c1-33-16-28(17-33)15-30-27(35)22-21-7-4-19-14-29-26(32-23(19)24(21)31-25(22)28)18-2-5-20(6-3-18)37-13-10-34-8-11-36-12-9-34/h2-3,5-6,14,31H,4,7-13,15-17H2,1H3,(H,30,35)	YAYDEGVHJWTXHD-UHFFFAOYSA-N	50348484	CHEMBL1801308	MAP kinase-activated protein kinase 2	Homo sapiens		 2800							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348484&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56666416	136355170		CHEMBL1801308				ZINC72109882	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649715	COc1ccc(cc1)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CN(C)C3)-c2n1	InChI=1S/C23H23N5O2/c1-28-11-23(12-28)10-25-22(29)17-16-8-5-14-9-24-21(13-3-6-15(30-2)7-4-13)27-18(14)19(16)26-20(17)23/h3-4,6-7,9,26H,5,8,10-12H2,1-2H3,(H,25,29)	JVYQTNRDLDLKCV-UHFFFAOYSA-N	50348485	CHEMBL1801306	MAP kinase-activated protein kinase 2	Homo sapiens		 3000							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348485&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42646706	136355171		CHEMBL1801306				ZINC68246365	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649716	COc1ccc(cc1)-c1cc2-c3[nH]c4CC5(CNC5)NC(=O)c4c3CCc2cn1	InChI=1S/C23H22N4O2/c1-29-15-5-2-13(3-6-15)18-8-17-14(10-25-18)4-7-16-20-19(26-21(16)17)9-23(11-24-12-23)27-22(20)28/h2-3,5-6,8,10,24,26H,4,7,9,11-12H2,1H3,(H,27,28)	PHUWYUDQWSFJAL-UHFFFAOYSA-N	50348486	CHEMBL1801294	MAP kinase-activated protein kinase 2	Homo sapiens		 3100							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348486&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42646445	136355172		CHEMBL1801294				ZINC72109350	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649717	O=C1NC2(CC2)Cc2[nH]c-3c(CCc4cnc(nc-34)-c3ccc(OCCN4CCOCC4)cc3)c12	InChI=1S/C27H29N5O3/c33-26-22-20-6-3-18-16-28-25(30-23(18)24(20)29-21(22)15-27(31-26)7-8-27)17-1-4-19(5-2-17)35-14-11-32-9-12-34-13-10-32/h1-2,4-5,16,29H,3,6-15H2,(H,31,33)	SMGWSZAEOZOSMS-UHFFFAOYSA-N	50348487	CHEMBL1801301	MAP kinase-activated protein kinase 2	Homo sapiens		 3200							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348487&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676658	136355173		CHEMBL1801301				ZINC72109361	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649718	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3oc21)-c1cccc(F)c1	InChI=1S/C23H20FN3O2/c1-27-11-23(12-27)10-26-22(28)19-16-6-5-14-9-25-18(13-3-2-4-15(24)7-13)8-17(14)20(16)29-21(19)23/h2-4,7-9H,5-6,10-12H2,1H3,(H,26,28)	DQUDFEQAGMVDDO-UHFFFAOYSA-N	50348488	CHEMBL1801310	MAP kinase-activated protein kinase 2	Homo sapiens		 3300							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348488&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679980	136355174		CHEMBL1801310				ZINC72110251	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649719	COCCOc1cncc(c1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCCc2cn1	InChI=1S/C23H24N4O3/c1-29-7-8-30-16-9-15(11-24-13-16)20-10-18-14(12-26-20)3-2-4-17-21-19(27-22(17)18)5-6-25-23(21)28/h9-13,27H,2-8H2,1H3,(H,25,28)	GYMYUYFFWPXNDR-UHFFFAOYSA-N	50348489	CHEMBL1801196	MAP kinase-activated protein kinase 2	Homo sapiens		 4300							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348489&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679974	136355175		CHEMBL1801196				ZINC72109816	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649720	COc1ccc(cc1)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C20H18N4O2/c1-26-13-5-2-11(3-6-13)19-22-10-12-4-7-14-16-15(8-9-21-20(16)25)23-18(14)17(12)24-19/h2-3,5-6,10,23H,4,7-9H2,1H3,(H,21,25)	RJYLNNKQMDZBDF-UHFFFAOYSA-N	50348490	CHEMBL1801297	MAP kinase-activated protein kinase 2	Homo sapiens		 4300							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348490&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659480	136355176		CHEMBL1801297				ZINC72107191	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649721	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(nc4-c3[nH]c21)-c1cccc(F)c1	InChI=1S/C22H20FN5O/c1-28-10-22(11-28)9-25-21(29)16-15-6-5-13-8-24-20(12-3-2-4-14(23)7-12)27-17(13)18(15)26-19(16)22/h2-4,7-8,26H,5-6,9-11H2,1H3,(H,25,29)	GVYMKFWWTKMJSR-UHFFFAOYSA-N	50348491	CHEMBL1801305	MAP kinase-activated protein kinase 2	Homo sapiens		 4500							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348491&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669833	136355177		CHEMBL1801305				ZINC72107952	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649722	CN1CCC2(CC1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C25H25FN4O/c1-30-10-8-25(9-11-30)14-28-24(31)21-17-7-6-15-13-27-20(16-4-2-3-5-19(16)26)12-18(15)22(17)29-23(21)25/h2-5,12-13,29H,6-11,14H2,1H3,(H,28,31)	YBBRQSXVZPVXFF-UHFFFAOYSA-N	50348492	CHEMBL1801296	MAP kinase-activated protein kinase 2	Homo sapiens		 4							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348492&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662943	136355178		CHEMBL1801296				ZINC72107190	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649723	COCCOc1cncc(c1)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CN(C)C3)-c2n1	InChI=1S/C24H26N6O3/c1-30-12-24(13-30)11-27-23(31)18-17-4-3-14-9-26-22(29-19(14)20(17)28-21(18)24)15-7-16(10-25-8-15)33-6-5-32-2/h7-10,28H,3-6,11-13H2,1-2H3,(H,27,31)	HFESUJIHZXOWFN-UHFFFAOYSA-N	50348493	CHEMBL1801304	MAP kinase-activated protein kinase 2	Homo sapiens		 6							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348493&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662944	136355179		CHEMBL1801304				ZINC72107951	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649724	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(nc4-c3[nH]c21)-c1cccc(F)c1	InChI=1S/C22H20FN5O/c1-28-10-22(11-28)9-25-21(29)16-15-6-5-13-8-24-20(12-3-2-4-14(23)7-12)27-17(13)18(15)26-19(16)22/h2-4,7-8,26H,5-6,9-11H2,1H3,(H,25,29)	GVYMKFWWTKMJSR-UHFFFAOYSA-N	50348491	CHEMBL1801305	MAP kinase-activated protein kinase 2	Homo sapiens		 6							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348491&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669833	136355177		CHEMBL1801305				ZINC72107952	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649725	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(nc4-c3[nH]c21)-c1ccc(F)nc1	InChI=1S/C21H19FN6O/c1-28-9-21(10-28)8-25-20(29)15-13-4-2-11-6-24-19(12-3-5-14(22)23-7-12)27-16(11)17(13)26-18(15)21/h3,5-7,26H,2,4,8-10H2,1H3,(H,25,29)	WPSLEAFBLLIBPF-UHFFFAOYSA-N	50348481	CHEMBL1801307	MAP kinase-activated protein kinase 2	Homo sapiens		 7							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348481&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679979	136355167		CHEMBL1801307				ZINC72109881	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649726	Fc1cccc(c1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C20H16FN3O/c21-13-3-1-2-11(8-13)17-9-15-12(10-23-17)4-5-14-18-16(24-19(14)15)6-7-22-20(18)25/h1-3,8-10,24H,4-7H2,(H,22,25)	KPIOYVVFFGHOBR-UHFFFAOYSA-N	50348494	CHEMBL1801274	MAP kinase-activated protein kinase 2	Homo sapiens		 8							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659478	136355180		CHEMBL1801274				ZINC72107572	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649727	COCCOc1cncc(c1)-c1cc2c3[nH]c4CCNC(=O)c4c3ccc2cn1	InChI=1S/C22H20N4O3/c1-28-6-7-29-15-8-14(10-23-12-15)19-9-17-13(11-25-19)2-3-16-20-18(26-21(16)17)4-5-24-22(20)27/h2-3,8-12,26H,4-7H2,1H3,(H,24,27)	ZYTDQGRQFPNBGA-UHFFFAOYSA-N	50348495	CHEMBL1614995	MAP kinase-activated protein kinase 2	Homo sapiens		 10							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348495&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	HGF	3M42	25066416	136355181		CHEMBL1614995				ZINC64744267	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649728	COc1ccc(cc1)-c1cc2-c3[nH]c4CC5(CNC5)NC(=O)c4c3CCc2cn1	InChI=1S/C23H22N4O2/c1-29-15-5-2-13(3-6-15)18-8-17-14(10-25-18)4-7-16-20-19(26-21(16)17)9-23(11-24-12-23)27-22(20)28/h2-3,5-6,8,10,24,26H,4,7,9,11-12H2,1H3,(H,27,28)	PHUWYUDQWSFJAL-UHFFFAOYSA-N	50348486	CHEMBL1801294	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348486&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42646445	136355172		CHEMBL1801294				ZINC72109350	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649729	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3n(C)c21)-c1ccccc1F	InChI=1S/C24H23FN4O/c1-28-12-24(13-28)11-27-23(30)20-16-8-7-14-10-26-19(15-5-3-4-6-18(15)25)9-17(14)21(16)29(2)22(20)24/h3-6,9-10H,7-8,11-13H2,1-2H3,(H,27,30)	RWHHQGYUDHQGSP-UHFFFAOYSA-N	50348480	CHEMBL1801312	MAP kinase-activated protein kinase 2	Homo sapiens		 13							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659481	136355166		CHEMBL1801312				ZINC72141130	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649730	Fc1ccccc1-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CNC1	InChI=1S/C22H19FN4O/c23-16-4-2-1-3-13(16)17-7-15-12(8-25-17)5-6-14-18-20(27-19(14)15)22(9-24-10-22)11-26-21(18)28/h1-4,7-8,24,27H,5-6,9-11H2,(H,26,28)	QMNKSAQTHXFFCG-UHFFFAOYSA-N	50348496	CHEMBL1801284	MAP kinase-activated protein kinase 2	Homo sapiens		 17							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348496&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673315	136355182		CHEMBL1801284				ZINC72108128	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649731	Cn1c-2c(CCc3cnc(cc-23)-c2ccccc2F)c2c1C1(CNC1)CNC2=O	InChI=1S/C23H21FN4O/c1-28-20-15(19-21(28)23(10-25-11-23)12-27-22(19)29)7-6-13-9-26-18(8-16(13)20)14-4-2-3-5-17(14)24/h2-5,8-9,25H,6-7,10-12H2,1H3,(H,27,29)	RWTCBSWLANXVDA-UHFFFAOYSA-N	50348497	CHEMBL1801311	MAP kinase-activated protein kinase 2	Homo sapiens		 20							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348497&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56666417	136355183		CHEMBL1801311				ZINC72110252	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649732	Fc1ccc(cn1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1	InChI=1S/C21H17FN4O/c22-16-4-2-12(9-24-16)15-7-14-11(8-23-15)1-3-13-17-19(26-18(13)14)21(5-6-21)10-25-20(17)27/h2,4,7-9,26H,1,3,5-6,10H2,(H,25,27)	FYDPOCATTVYCMF-UHFFFAOYSA-N	50348498	CHEMBL1801283	MAP kinase-activated protein kinase 2	Homo sapiens		 27							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348498&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676653	136355184		CHEMBL1801283				ZINC72108508	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649733	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(nc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C22H20FN5O/c1-28-10-22(11-28)9-25-21(29)16-14-7-6-12-8-24-20(13-4-2-3-5-15(13)23)27-17(12)18(14)26-19(16)22/h2-5,8,26H,6-7,9-11H2,1H3,(H,25,29)	WZCAUTBYHZBYBT-UHFFFAOYSA-N	50348499	CHEMBL1801303	MAP kinase-activated protein kinase 2	Homo sapiens		 34							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348499&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673319	136355185		CHEMBL1801303				ZINC72107305	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649734	Fc1ccccc1-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C20H16FN3O/c21-15-4-2-1-3-12(15)17-9-14-11(10-23-17)5-6-13-18-16(24-19(13)14)7-8-22-20(18)25/h1-4,9-10,24H,5-8H2,(H,22,25)	BKXIFWPZQGIBQU-UHFFFAOYSA-N	50348483	CHEMBL1801194	MAP kinase-activated protein kinase 2	Homo sapiens		 37							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348483&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676644	136355169		CHEMBL1801194				ZINC72108987	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649735	COCCOc1cncc(c1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C22H22N4O3/c1-28-6-7-29-15-8-14(10-23-12-15)19-9-17-13(11-25-19)2-3-16-20-18(26-21(16)17)4-5-24-22(20)27/h8-12,26H,2-7H2,1H3,(H,24,27)	LVZFXQCXIOECDX-UHFFFAOYSA-N	50348479	CHEMBL1801195	MAP kinase-activated protein kinase 2	Homo sapiens		 40							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348479&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673312	136355165		CHEMBL1801195				ZINC72109815	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649736	COc1ccc(cc1)-c1cc2-c3[nH]c4CC5(CN(C)C5)NC(=O)c4c3CCc2cn1	InChI=1S/C24H24N4O2/c1-28-12-24(13-28)10-20-21(23(29)27-24)17-8-5-15-11-25-19(9-18(15)22(17)26-20)14-3-6-16(30-2)7-4-14/h3-4,6-7,9,11,26H,5,8,10,12-13H2,1-2H3,(H,27,29)	PCOZFCUKHHNFQO-UHFFFAOYSA-N	50348500	CHEMBL1801295	MAP kinase-activated protein kinase 2	Homo sapiens		 45							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348500&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56683316	136355186		CHEMBL1801295				ZINC72109304	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649737	Fc1ccc(cn1)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C21H17FN4O/c22-17-4-2-12(10-24-17)15-7-14-11(9-23-15)1-3-13-18-16(25-19(13)14)8-21(5-6-21)26-20(18)27/h2,4,7,9-10,25H,1,3,5-6,8H2,(H,26,27)	XQSNJSIECSWSOW-UHFFFAOYSA-N	50348501	CHEMBL1801279	MAP kinase-activated protein kinase 2	Homo sapiens		 50							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348501&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42646446	136355187		CHEMBL1801279				ZINC68246364	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649738	COc1ccc(cc1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C21H19N3O2/c1-26-14-5-2-12(3-6-14)18-10-16-13(11-23-18)4-7-15-19-17(24-20(15)16)8-9-22-21(19)25/h2-3,5-6,10-11,24H,4,7-9H2,1H3,(H,22,25)	REVLWXOESFWXGT-UHFFFAOYSA-N	50348502	CHEMBL1801275	MAP kinase-activated protein kinase 2	Homo sapiens		 80							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348502&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662940	136355188		CHEMBL1801275				ZINC72112279	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649739	O=C1NC2(CC2)Cc2[nH]c-3c(CCc4cnc(cc-34)-c3ccc(OCCN4CCOCC4)cc3)c12	InChI=1S/C28H30N4O3/c33-27-25-21-6-3-19-17-29-23(15-22(19)26(21)30-24(25)16-28(31-27)7-8-28)18-1-4-20(5-2-18)35-14-11-32-9-12-34-13-10-32/h1-2,4-5,15,17,30H,3,6-14,16H2,(H,31,33)	SARIWGYGUMNBIO-UHFFFAOYSA-N	50348503	CHEMBL1801280	MAP kinase-activated protein kinase 2	Homo sapiens		 100							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348503&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56683315	136355189		CHEMBL1801280				ZINC72111369	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649740	Fc1cccc(c1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1	InChI=1S/C22H18FN3O/c23-14-3-1-2-12(8-14)17-9-16-13(10-24-17)4-5-15-18-20(26-19(15)16)22(6-7-22)11-25-21(18)27/h1-3,8-10,26H,4-7,11H2,(H,25,27)	OSHCYABVVJIJAJ-UHFFFAOYSA-N	50348504	CHEMBL1801281	MAP kinase-activated protein kinase 2	Homo sapiens		 100							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348504&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659479	136355190		CHEMBL1801281				ZINC72112548	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649741	Fc1ccccc1-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CNC1	InChI=1S/C22H19FN4O/c23-16-4-2-1-3-13(16)17-7-15-12(8-25-17)5-6-14-18-20(27-19(14)15)22(9-24-10-22)11-26-21(18)28/h1-4,7-8,24,27H,5-6,9-11H2,(H,26,28)	QMNKSAQTHXFFCG-UHFFFAOYSA-N	50348496	CHEMBL1801284	MAP kinase-activated protein kinase 2	Homo sapiens		 100							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348496&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673315	136355182		CHEMBL1801284				ZINC72108128	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649742	Fc1ccc(cn1)-c1ncc2CCc3c([nH]c4CC5(CC5)NC(=O)c34)-c2n1	InChI=1S/C20H16FN5O/c21-14-4-2-11(9-22-14)18-23-8-10-1-3-12-15-13(24-17(12)16(10)25-18)7-20(5-6-20)26-19(15)27/h2,4,8-9,24H,1,3,5-7H2,(H,26,27)	PQIFLRBLEHCDKA-UHFFFAOYSA-N	50348505	CHEMBL1801300	MAP kinase-activated protein kinase 2	Homo sapiens		 120							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348505&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673318	136355191		CHEMBL1801300				ZINC72108989	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649743	COc1ccc(cc1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1	InChI=1S/C23H21N3O2/c1-28-15-5-2-13(3-6-15)18-10-17-14(11-24-18)4-7-16-19-21(26-20(16)17)23(8-9-23)12-25-22(19)27/h2-3,5-6,10-11,26H,4,7-9,12H2,1H3,(H,25,27)	UIYTURGPTUSRBA-UHFFFAOYSA-N	50348506	CHEMBL1801282	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348506&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56666414	136355192		CHEMBL1801282				ZINC72108507	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649744	Fc1ccccc1-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C22H18FN3O/c23-16-4-2-1-3-13(16)17-9-15-12(11-24-17)5-6-14-19-18(25-20(14)15)10-22(7-8-22)26-21(19)27/h1-4,9,11,25H,5-8,10H2,(H,26,27)	OJIIULQRCICCLG-UHFFFAOYSA-N	50348507	CHEMBL1801276	MAP kinase-activated protein kinase 2	Homo sapiens		 140							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348507&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669830	136355193		CHEMBL1801276				ZINC72112485	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649745	COc1ccc(cc1)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CC3)-c2n1	InChI=1S/C22H20N4O2/c1-28-14-5-2-12(3-6-14)20-23-10-13-4-7-15-16-19(25-18(15)17(13)26-20)22(8-9-22)11-24-21(16)27/h2-3,5-6,10,25H,4,7-9,11H2,1H3,(H,24,27)	VNTJTSKIEIMYPD-UHFFFAOYSA-N	50348508	CHEMBL1801302	MAP kinase-activated protein kinase 2	Homo sapiens		 150							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348508&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42646194	136355194		CHEMBL1801302				ZINC72107304	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649746	COc1ccc(cc1)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C23H21N3O2/c1-28-15-5-2-13(3-6-15)18-10-17-14(12-24-18)4-7-16-20-19(25-21(16)17)11-23(8-9-23)26-22(20)27/h2-3,5-6,10,12,25H,4,7-9,11H2,1H3,(H,26,27)	FZMLHUYYSNMZKW-UHFFFAOYSA-N	50348509	CHEMBL1801278	MAP kinase-activated protein kinase 2	Homo sapiens		 175							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348509&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679977	136355195		CHEMBL1801278				ZINC68246366	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649747	COCCOc1cncc(c1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCCc2cn1	InChI=1S/C23H24N4O3/c1-29-7-8-30-16-9-15(11-24-13-16)20-10-18-14(12-26-20)3-2-4-17-21-19(27-22(17)18)5-6-25-23(21)28/h9-13,27H,2-8H2,1H3,(H,25,28)	GYMYUYFFWPXNDR-UHFFFAOYSA-N	50348489	CHEMBL1801196	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348489&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679974	136355175		CHEMBL1801196				ZINC72109816	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649748	O=C1NC2(CC2)Cc2[nH]c-3c(CCc4cnc(nc-34)-c3ccc(OCCN4CCOCC4)cc3)c12	InChI=1S/C27H29N5O3/c33-26-22-20-6-3-18-16-28-25(30-23(18)24(20)29-21(22)15-27(31-26)7-8-27)17-1-4-19(5-2-17)35-14-11-32-9-12-34-13-10-32/h1-2,4-5,16,29H,3,6-15H2,(H,31,33)	SMGWSZAEOZOSMS-UHFFFAOYSA-N	50348487	CHEMBL1801301	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348487&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676658	136355173		CHEMBL1801301				ZINC72109361	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649749	Fc1cccc(c1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CNC1	InChI=1S/C22H19FN4O/c23-14-3-1-2-12(6-14)17-7-16-13(8-25-17)4-5-15-18-20(27-19(15)16)22(9-24-10-22)11-26-21(18)28/h1-3,6-8,24,27H,4-5,9-11H2,(H,26,28)	IRRXSIKWWQZKJR-UHFFFAOYSA-N	50348510	CHEMBL1801285	MAP kinase-activated protein kinase 2	Homo sapiens		 200							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348510	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348510&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676654	136355196		CHEMBL1801285				ZINC72108129	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649750	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1cccc(F)c1	InChI=1S/C23H21FN4O/c1-28-11-23(12-28)10-26-22(29)19-16-6-5-14-9-25-18(13-3-2-4-15(24)7-13)8-17(14)20(16)27-21(19)23/h2-4,7-9,27H,5-6,10-12H2,1H3,(H,26,29)	WJYYYNSFUNMPRF-UHFFFAOYSA-N	50348511	CHEMBL1801287	MAP kinase-activated protein kinase 2	Homo sapiens		 200							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348511	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348511&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669832	136355197		CHEMBL1801287				ZINC72107728	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649751	Fc1cccc(c1)-c1cc2-c3oc4c(c3CCc2cn1)C(=O)NCC41CNC1	InChI=1S/C22H18FN3O2/c23-14-3-1-2-12(6-14)17-7-16-13(8-25-17)4-5-15-18-20(28-19(15)16)22(9-24-10-22)11-26-21(18)27/h1-3,6-8,24H,4-5,9-11H2,(H,26,27)	WNLOCCXVPMELDQ-UHFFFAOYSA-N	50348512	CHEMBL1801309	MAP kinase-activated protein kinase 2	Homo sapiens		 200							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348512&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669834	136355198		CHEMBL1801309				ZINC72110250	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649752	CN1CC2(C1)CNC(=O)c1c3Cc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C22H19FN4O/c1-27-10-22(11-27)9-25-21(28)18-15-6-12-8-24-17(13-4-2-3-5-16(13)23)7-14(12)19(15)26-20(18)22/h2-5,7-8,26H,6,9-11H2,1H3,(H,25,28)	CGWPHUQUDGTDTM-UHFFFAOYSA-N	50348513	CHEMBL1801273	MAP kinase-activated protein kinase 2	Homo sapiens		 230							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348513&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659477	136355199		CHEMBL1801273				ZINC72111508	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649753	Fc1cccc(c1)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C22H18FN3O/c23-14-3-1-2-12(8-14)17-9-16-13(11-24-17)4-5-15-19-18(25-20(15)16)10-22(6-7-22)26-21(19)27/h1-3,8-9,11,25H,4-7,10H2,(H,26,27)	YCDCMENBXGGZOJ-UHFFFAOYSA-N	50348514	CHEMBL1801277	MAP kinase-activated protein kinase 2	Homo sapiens		 230							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348514&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662941	136355200		CHEMBL1801277				ZINC72112486	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649754	COc1ccc(cc1)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C20H18N4O2/c1-26-13-5-2-11(3-6-13)19-22-10-12-4-7-14-16-15(8-9-21-20(16)25)23-18(14)17(12)24-19/h2-3,5-6,10,23H,4,7-9H2,1H3,(H,21,25)	RJYLNNKQMDZBDF-UHFFFAOYSA-N	50348490	CHEMBL1801297	MAP kinase-activated protein kinase 2	Homo sapiens		 270							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348490&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659480	136355176		CHEMBL1801297				ZINC72107191	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649755	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C23H21FN4O/c1-28-11-23(12-28)10-26-22(29)19-15-7-6-13-9-25-18(14-4-2-3-5-17(14)24)8-16(13)20(15)27-21(19)23/h2-5,8-9,27H,6-7,10-12H2,1H3,(H,26,29)	XZZOJFOFCDHYRX-UHFFFAOYSA-N	50348515	CHEMBL1233942	MAP kinase-activated protein kinase 2	Homo sapiens		<3							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348515	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348515&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	L8I	3M2W	42646698	136355201		CHEMBL1233942				ZINC58638744	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649756	Fc1cccc(c1)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C22H18FN3O/c23-14-3-1-2-12(8-14)17-9-16-13(11-24-17)4-5-15-19-18(25-20(15)16)10-22(6-7-22)26-21(19)27/h1-3,8-9,11,25H,4-7,10H2,(H,26,27)	YCDCMENBXGGZOJ-UHFFFAOYSA-N	50348514	CHEMBL1801277	MAP kinase-activated protein kinase 2	Homo sapiens		 500							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348514	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348514&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662941	136355200		CHEMBL1801277				ZINC72112486	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649757	Fc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14FN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	XJJYJNMNYDNXNO-UHFFFAOYSA-N	30192	Pyrrolopyridine, 23	MAP kinase-activated protein kinase 2	Homo sapiens		 560							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30192&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	F10	3FXW,2P3G	11992146	85147952			DB07728			ZINC16052794	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649758	COc1ccc(cc1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C21H19N3O2/c1-26-14-5-2-12(3-6-14)18-10-16-13(11-23-18)4-7-15-19-17(24-20(15)16)8-9-22-21(19)25/h2-3,5-6,10-11,24H,4,7-9H2,1H3,(H,22,25)	REVLWXOESFWXGT-UHFFFAOYSA-N	50348502	CHEMBL1801275	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348502&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662940	136355188		CHEMBL1801275				ZINC72112279	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649759	Fc1ccccc1-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C22H18FN3O/c23-16-4-2-1-3-13(16)17-9-15-12(11-24-17)5-6-14-19-18(25-20(14)15)10-22(7-8-22)26-21(19)27/h1-4,9,11,25H,5-8,10H2,(H,26,27)	OJIIULQRCICCLG-UHFFFAOYSA-N	50348507	CHEMBL1801276	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348507	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348507&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669830	136355193		CHEMBL1801276				ZINC72112485	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649760	COc1ccc(cc1)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C23H21N3O2/c1-28-15-5-2-13(3-6-15)18-10-17-14(12-24-18)4-7-16-20-19(25-21(16)17)11-23(8-9-23)26-22(20)27/h2-3,5-6,10,12,25H,4,7-9,11H2,1H3,(H,26,27)	FZMLHUYYSNMZKW-UHFFFAOYSA-N	50348509	CHEMBL1801278	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348509	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348509&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679977	136355195		CHEMBL1801278				ZINC68246366	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649761	COc1ccc(cc1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CN(C)C1	InChI=1S/C24H24N4O2/c1-28-12-24(13-28)11-26-23(29)20-17-8-5-15-10-25-19(9-18(15)21(17)27-22(20)24)14-3-6-16(30-2)7-4-14/h3-4,6-7,9-10,27H,5,8,11-13H2,1-2H3,(H,26,29)	KQIODUAXCRMNES-UHFFFAOYSA-N	50348516	CHEMBL1801288	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348516	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348516&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676655	136355202		CHEMBL1801288				ZINC72109975	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649762	CN1CCC2(CC1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C25H25FN4O/c1-30-10-8-25(9-11-30)14-28-24(31)21-17-7-6-15-13-27-20(16-4-2-3-5-19(16)26)12-18(15)22(17)29-23(21)25/h2-5,12-13,29H,6-11,14H2,1H3,(H,28,31)	YBBRQSXVZPVXFF-UHFFFAOYSA-N	50348492	CHEMBL1801296	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348492&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662943	136355178		CHEMBL1801296				ZINC72107190	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649763	Fc1ccccc1-c1ncc2CCc3c([nH]c4CC5(CC5)NC(=O)c34)-c2n1	InChI=1S/C21H17FN4O/c22-14-4-2-1-3-12(14)19-23-10-11-5-6-13-16-15(24-18(13)17(11)25-19)9-21(7-8-21)26-20(16)27/h1-4,10,24H,5-9H2,(H,26,27)	WLRWABLVEWKIFU-UHFFFAOYSA-N	50348517	CHEMBL1801298	MAP kinase-activated protein kinase 2	Homo sapiens		 860							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348517&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676657	136355203		CHEMBL1801298				ZINC72109360	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649764	Fc1cccc(c1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1	InChI=1S/C22H18FN3O/c23-14-3-1-2-12(8-14)17-9-16-13(10-24-17)4-5-15-18-20(26-19(15)16)22(6-7-22)11-25-21(18)27/h1-3,8-10,26H,4-7,11H2,(H,25,27)	OSHCYABVVJIJAJ-UHFFFAOYSA-N	50348504	CHEMBL1801281	MAP kinase-activated protein kinase 2	Homo sapiens		 900							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348504&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659479	136355190		CHEMBL1801281				ZINC72112548	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649765	COc1ccc(cc1)-c1ncc2CCc3c([nH]c4CC5(CC5)NC(=O)c34)-c2n1	InChI=1S/C22H20N4O2/c1-28-14-5-2-12(3-6-14)20-23-11-13-4-7-15-17-16(24-19(15)18(13)25-20)10-22(8-9-22)26-21(17)27/h2-3,5-6,11,24H,4,7-10H2,1H3,(H,26,27)	NGTDZYCIPFIDGW-UHFFFAOYSA-N	50348482	CHEMBL1801299	MAP kinase-activated protein kinase 2	Homo sapiens		 900							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348482&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673317	136355168		CHEMBL1801299				ZINC72108945	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649766	Fc1ccc(cn1)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C21H17FN4O/c22-17-4-2-12(10-24-17)15-7-14-11(9-23-15)1-3-13-18-16(25-19(13)14)8-21(5-6-21)26-20(18)27/h2,4,7,9-10,25H,1,3,5-6,8H2,(H,26,27)	XQSNJSIECSWSOW-UHFFFAOYSA-N	50348501	CHEMBL1801279	MAP kinase-activated protein kinase 2	Homo sapiens		 1100							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348501&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42646446	136355187		CHEMBL1801279				ZINC68246364	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649767	COc1ccc(cc1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1	InChI=1S/C23H21N3O2/c1-28-15-5-2-13(3-6-15)18-10-17-14(11-24-18)4-7-16-19-21(26-20(16)17)23(8-9-23)12-25-22(19)27/h2-3,5-6,10-11,26H,4,7-9,12H2,1H3,(H,25,27)	UIYTURGPTUSRBA-UHFFFAOYSA-N	50348506	CHEMBL1801282	MAP kinase-activated protein kinase 2	Homo sapiens		 1200							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348506&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56666414	136355192		CHEMBL1801282				ZINC72108507	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649768	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccc(F)nc1	InChI=1S/C22H20FN5O/c1-28-10-22(11-28)9-26-21(29)18-14-4-2-12-7-24-16(13-3-5-17(23)25-8-13)6-15(12)19(14)27-20(18)22/h3,5-8,27H,2,4,9-11H2,1H3,(H,26,29)	PSLJFZFZLOVUSG-UHFFFAOYSA-N	50348518	CHEMBL1801289	MAP kinase-activated protein kinase 2	Homo sapiens		 1200							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348518	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348518&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56666415	136355204		CHEMBL1801289				ZINC72110060	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649769	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccc(OCCN2CCOCC2)cc1	InChI=1S/C29H33N5O3/c1-33-17-29(18-33)16-31-28(35)25-22-7-4-20-15-30-24(14-23(20)26(22)32-27(25)29)19-2-5-21(6-3-19)37-13-10-34-8-11-36-12-9-34/h2-3,5-6,14-15,32H,4,7-13,16-18H2,1H3,(H,31,35)	KHZSCWAZHGMNRI-UHFFFAOYSA-N	50348519	CHEMBL1801290	MAP kinase-activated protein kinase 2	Homo sapiens		 1200							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348519	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348519&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676656	136355205		CHEMBL1801290				ZINC72110061	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649770	Cn1c-2c(CCc3cnc(cc-23)-c2ccccc2F)c2c1C1(CNC1)CNC2=O	InChI=1S/C23H21FN4O/c1-28-20-15(19-21(28)23(10-25-11-23)12-27-22(19)29)7-6-13-9-26-18(8-16(13)20)14-4-2-3-5-17(14)24/h2-5,8-9,25H,6-7,10-12H2,1H3,(H,27,29)	RWTCBSWLANXVDA-UHFFFAOYSA-N	50348497	CHEMBL1801311	MAP kinase-activated protein kinase 2	Homo sapiens		 1300							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348497&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56666417	136355183		CHEMBL1801311				ZINC72110252	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649771	O=C1NC2(CC2)Cc2[nH]c-3c(CCc4cnc(cc-34)-c3ccc(OCCN4CCOCC4)cc3)c12	InChI=1S/C28H30N4O3/c33-27-25-21-6-3-19-17-29-23(15-22(19)26(21)30-24(25)16-28(31-27)7-8-28)18-1-4-20(5-2-18)35-14-11-32-9-12-34-13-10-32/h1-2,4-5,15,17,30H,3,6-14,16H2,(H,31,33)	SARIWGYGUMNBIO-UHFFFAOYSA-N	50348503	CHEMBL1801280	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348503&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56683315	136355189		CHEMBL1801280				ZINC72111369	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649772	Fc1ccc(cn1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CC1	InChI=1S/C21H17FN4O/c22-16-4-2-12(9-24-16)15-7-14-11(8-23-15)1-3-13-17-19(26-18(13)14)21(5-6-21)10-25-20(17)27/h2,4,7-9,26H,1,3,5-6,10H2,(H,25,27)	FYDPOCATTVYCMF-UHFFFAOYSA-N	50348498	CHEMBL1801283	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348498&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676653	136355184		CHEMBL1801283				ZINC72108508	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649773	COCCCOc1cncc(c1)-c1cc2-c3[nH]c4c(c3CCc2cn1)C(=O)NCC41CN(C)C1	InChI=1S/C26H29N5O3/c1-31-14-26(15-31)13-29-25(32)22-19-5-4-16-11-28-21(9-20(16)23(19)30-24(22)26)17-8-18(12-27-10-17)34-7-3-6-33-2/h8-12,30H,3-7,13-15H2,1-2H3,(H,29,32)	GSLSEAKPERDTFS-UHFFFAOYSA-N	50348520	CHEMBL1801286	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348520&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669831	136355206		CHEMBL1801286				ZINC72108130	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649774	COc1ccc(cc1)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CC3)-c2n1	InChI=1S/C22H20N4O2/c1-28-14-5-2-12(3-6-14)20-23-10-13-4-7-15-16-19(25-18(15)17(13)26-20)22(8-9-22)11-24-21(16)27/h2-3,5-6,10,25H,4,7-9,11H2,1H3,(H,24,27)	VNTJTSKIEIMYPD-UHFFFAOYSA-N	50348508	CHEMBL1801302	MAP kinase-activated protein kinase 2	Homo sapiens		 5600							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348508	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348508&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			42646194	136355194		CHEMBL1801302				ZINC72107304	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649775	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(nc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C22H20FN5O/c1-28-10-22(11-28)9-25-21(29)16-14-7-6-12-8-24-20(13-4-2-3-5-15(13)23)27-17(12)18(14)26-19(16)22/h2-5,8,26H,6-7,9-11H2,1H3,(H,25,29)	WZCAUTBYHZBYBT-UHFFFAOYSA-N	50348499	CHEMBL1801303	MAP kinase-activated protein kinase 2	Homo sapiens		 5600							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348499&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673319	136355185		CHEMBL1801303				ZINC72107305	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649776	FCCN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C24H22F2N4O/c25-7-8-30-12-24(13-30)11-28-23(31)20-16-6-5-14-10-27-19(15-3-1-2-4-18(15)26)9-17(14)21(16)29-22(20)24/h1-4,9-10,29H,5-8,11-13H2,(H,28,31)	KDRFJIJZKJTCRP-UHFFFAOYSA-N	50348521	CHEMBL1801292	MAP kinase-activated protein kinase 2	Homo sapiens		 6500							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348521&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679978	136355207		CHEMBL1801292				ZINC72109287	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649777	COCCOc1cncc(c1)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CN(C)C3)-c2n1	InChI=1S/C24H26N6O3/c1-30-12-24(13-30)11-27-23(31)18-17-4-3-14-9-26-22(29-19(14)20(17)28-21(18)24)15-7-16(10-25-8-15)33-6-5-32-2/h7-10,28H,3-6,11-13H2,1-2H3,(H,27,31)	HFESUJIHZXOWFN-UHFFFAOYSA-N	50348493	CHEMBL1801304	MAP kinase-activated protein kinase 2	Homo sapiens		 6700							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348493&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662944	136355179		CHEMBL1801304				ZINC72107951	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649778	CN1CC2(C1)CNC(=O)c1c3Cc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C22H19FN4O/c1-27-10-22(11-27)9-25-21(28)18-15-6-12-8-24-17(13-4-2-3-5-16(13)23)7-14(12)19(15)26-20(18)22/h2-5,7-8,26H,6,9-11H2,1H3,(H,25,28)	CGWPHUQUDGTDTM-UHFFFAOYSA-N	50348513	CHEMBL1801273	MAP kinase-activated protein kinase 2	Homo sapiens		 10000							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348513	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348513&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659477	136355199		CHEMBL1801273				ZINC72111508	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649779	Fc1ccc(cn1)-c1ncc2CCc3c([nH]c4CC5(CC5)NC(=O)c34)-c2n1	InChI=1S/C20H16FN5O/c21-14-4-2-11(9-22-14)18-23-8-10-1-3-12-15-13(24-17(12)16(10)25-18)7-20(5-6-20)26-19(15)27/h2,4,8-9,24H,1,3,5-7H2,(H,26,27)	PQIFLRBLEHCDKA-UHFFFAOYSA-N	50348505	CHEMBL1801300	MAP kinase-activated protein kinase 2	Homo sapiens		 12000							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348505&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673318	136355191		CHEMBL1801300				ZINC72108989	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649780	Fc1ccccc1-c1ncc2CCc3c([nH]c4CC5(CC5)NC(=O)c34)-c2n1	InChI=1S/C21H17FN4O/c22-14-4-2-1-3-12(14)19-23-10-11-5-6-13-16-15(24-18(13)17(11)25-19)9-21(7-8-21)26-20(16)27/h1-4,10,24H,5-9H2,(H,26,27)	WLRWABLVEWKIFU-UHFFFAOYSA-N	50348517	CHEMBL1801298	MAP kinase-activated protein kinase 2	Homo sapiens		 15300							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348517	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348517&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676657	136355203		CHEMBL1801298				ZINC72109360	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649781	COc1ccc(cc1)-c1cc2-c3[nH]c4CC5(CN(C)C5)NC(=O)c4c3CCc2cn1	InChI=1S/C24H24N4O2/c1-28-12-24(13-28)10-20-21(23(29)27-24)17-8-5-15-11-25-19(9-18(15)22(17)26-20)14-3-6-16(30-2)7-4-14/h3-4,6-7,9,11,26H,5,8,10,12-13H2,1-2H3,(H,27,29)	PCOZFCUKHHNFQO-UHFFFAOYSA-N	50348500	CHEMBL1801295	MAP kinase-activated protein kinase 2	Homo sapiens		 17000							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348500&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56683316	136355186		CHEMBL1801295				ZINC72109304	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649782	Fc1cccc(c1)-c1cc2-c3oc4c(c3CCc2cn1)C(=O)NCC41CNC1	InChI=1S/C22H18FN3O2/c23-14-3-1-2-12(6-14)17-7-16-13(8-25-17)4-5-15-18-20(28-19(15)16)22(9-24-10-22)11-26-21(18)27/h1-3,6-8,24H,4-5,9-11H2,(H,26,27)	WNLOCCXVPMELDQ-UHFFFAOYSA-N	50348512	CHEMBL1801309	MAP kinase-activated protein kinase 2	Homo sapiens		 17000							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348512	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348512&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669834	136355198		CHEMBL1801309				ZINC72110250	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649783	CC(=O)N1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C24H21FN4O2/c1-13(30)29-11-24(12-29)10-27-23(31)20-16-7-6-14-9-26-19(15-4-2-3-5-18(15)25)8-17(14)21(16)28-22(20)24/h2-5,8-9,28H,6-7,10-12H2,1H3,(H,27,31)	QQKZBJOOMPFURC-UHFFFAOYSA-N	50348522	CHEMBL1801293	MAP kinase-activated protein kinase 2	Homo sapiens		 25000							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348522&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662942	136355208		CHEMBL1801293				ZINC72109349	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649784	COCCOc1cncc(c1)-c1cc2c3[nH]c4CCNC(=O)c4c3ccc2cn1	InChI=1S/C22H20N4O3/c1-28-6-7-29-15-8-14(10-23-12-15)19-9-17-13(11-25-19)2-3-16-20-18(26-21(16)17)4-5-24-22(20)27/h2-3,8-12,26H,4-7H2,1H3,(H,24,27)	ZYTDQGRQFPNBGA-UHFFFAOYSA-N	50348495	CHEMBL1614995	MAP kinase-activated protein kinase 2	Homo sapiens		 1500							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348495&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	HGF	3M42	25066416	136355181		CHEMBL1614995				ZINC64744267	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649785	CCN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C24H23FN4O/c1-2-29-12-24(13-29)11-27-23(30)20-16-8-7-14-10-26-19(15-5-3-4-6-18(15)25)9-17(14)21(16)28-22(20)24/h3-6,9-10,28H,2,7-8,11-13H2,1H3,(H,27,30)	UOMHQTLFZRDKJX-UHFFFAOYSA-N	50348523	CHEMBL1801291	MAP kinase-activated protein kinase 2	Homo sapiens		 1500							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348523	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348523&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56673316	136355209		CHEMBL1801291				ZINC72110062	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649786	CC(=O)N1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C24H21FN4O2/c1-13(30)29-11-24(12-29)10-27-23(31)20-16-7-6-14-9-26-19(15-4-2-3-5-18(15)25)8-17(14)21(16)28-22(20)24/h2-5,8-9,28H,6-7,10-12H2,1H3,(H,27,31)	QQKZBJOOMPFURC-UHFFFAOYSA-N	50348522	CHEMBL1801293	MAP kinase-activated protein kinase 2	Homo sapiens		 120							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348522	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348522&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56662942	136355208		CHEMBL1801293				ZINC72109349	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649787	FCCN1CC2(C1)CNC(=O)c1c3CCc4cnc(cc4-c3[nH]c21)-c1ccccc1F	InChI=1S/C24H22F2N4O/c25-7-8-30-12-24(13-30)11-28-23(31)20-16-6-5-14-10-27-19(15-3-1-2-4-18(15)26)9-17(14)21(16)29-22(20)24/h1-4,9-10,29H,5-8,11-13H2,(H,28,31)	KDRFJIJZKJTCRP-UHFFFAOYSA-N	50348521	CHEMBL1801292	MAP kinase-activated protein kinase 2	Homo sapiens		 230							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348521	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348521&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56679978	136355207		CHEMBL1801292				ZINC72109287	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649788	Fc1cccc(c1)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C20H16FN3O/c21-13-3-1-2-11(8-13)17-9-15-12(10-23-17)4-5-14-18-16(24-19(14)15)6-7-22-20(18)25/h1-3,8-10,24H,4-7H2,(H,22,25)	KPIOYVVFFGHOBR-UHFFFAOYSA-N	50348494	CHEMBL1801274	MAP kinase-activated protein kinase 2	Homo sapiens		 1300							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659478	136355180		CHEMBL1801274				ZINC72107572	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649789	Fc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C18H14FN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)	XJJYJNMNYDNXNO-UHFFFAOYSA-N	30192	Pyrrolopyridine, 23	MAP kinase-activated protein kinase 2	Homo sapiens		 8900							ChEMBL	10.1016/j.bmcl.2010.04.023	10.7270/Q2BZ66C2	20591669			Revesz, L; Schlapbach, A; Aichholz, R; Dawson, J; Feifel, R; Hawtin, S; Littlewood-Evans, A; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=30192	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=30192&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	F10	3FXW,2P3G	11992146	85147952			DB07728			ZINC16052794	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649797	NCc1[nH]c2c(ccc3cnc(\C=C\c4ccccc4)cc23)c1C(O)=O	InChI=1S/C21H17N3O2/c22-11-18-19(21(25)26)16-9-7-14-12-23-15(10-17(14)20(16)24-18)8-6-13-4-2-1-3-5-13/h1-10,12,24H,11,22H2,(H,25,26)/b8-6+	QSUYYWWTHNUYJR-SOFGYWHQSA-N	50348530	CHEMBL1801313	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348530&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24748251	136355216		CHEMBL1801313				ZINC45821223	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649798	CNCc1[nH]c2c(ccc3cnc(\C=C\c4ccccc4)cc23)c1C(O)=O	InChI=1S/C22H19N3O2/c1-23-13-19-20(22(26)27)17-10-8-15-12-24-16(11-18(15)21(17)25-19)9-7-14-5-3-2-4-6-14/h2-12,23,25H,13H2,1H3,(H,26,27)/b9-7+	WZGVYXNLNAIQSB-VQHVLOKHSA-N	50348531	CHEMBL1801314	MAP kinase-activated protein kinase 2	Homo sapiens		 60							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348531&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659482	136355217		CHEMBL1801314				ZINC72109182	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649799	OC1=NOCc2[nH]c3c(ccc4cnc(C=Cc5ccccc5)cc34)c12	InChI=1S/C21H15N3O2/c25-21-19-16-9-7-14-11-22-15(8-6-13-4-2-1-3-5-13)10-17(14)20(16)23-18(19)12-26-24-21/h1-11,23H,12H2,(H,24,25)	DBMVISJMXLUOQS-UHFFFAOYSA-N	50348532	CHEMBL1801315	MAP kinase-activated protein kinase 2	Homo sapiens		 25							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348532	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348532&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064099	136355218		CHEMBL1801315				ZINC72109099	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649800	COc1ccc(cc1)-c1cc2c3[nH]c4CN(C)NC(=O)c4c3ccc2cn1	InChI=1S/C21H18N4O2/c1-25-11-18-19(21(26)24-25)15-8-5-13-10-22-17(9-16(13)20(15)23-18)12-3-6-14(27-2)7-4-12/h3-10,23H,11H2,1-2H3,(H,24,26)	WWFURUYYQWIHRV-UHFFFAOYSA-N	50348533	CHEMBL1801316	MAP kinase-activated protein kinase 2	Homo sapiens		 23							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348533&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669835	136355219		CHEMBL1801316				ZINC72110949	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649801	O=C1NCc2[nH]c3c(ccc4cnc(\C=C\c5ccccc5)cc34)c12	InChI=1S/C21H15N3O/c25-21-19-16-9-7-14-11-22-15(8-6-13-4-2-1-3-5-13)10-17(14)20(16)24-18(19)12-23-21/h1-11,24H,12H2,(H,23,25)/b8-6+	VQQDOYPJOLNJQP-SOFGYWHQSA-N	50348534	CHEMBL1801373	MAP kinase-activated protein kinase 2	Homo sapiens		 10							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348534&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064093	136355220		CHEMBL1801373				ZINC72109924	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649802	O=C1NCc2[nH]c3c(ccc4cnc(\C=C\c5ccc(CN6CCOCC6)cc5)cc34)c12	InChI=1S/C26H24N4O2/c31-26-24-21-8-6-19-14-27-20(13-22(19)25(21)29-23(24)15-28-26)7-5-17-1-3-18(4-2-17)16-30-9-11-32-12-10-30/h1-8,13-14,29H,9-12,15-16H2,(H,28,31)/b7-5+	ISLMQWLFRPLLLI-FNORWQNLSA-N	50348535	CHEMBL1801374	MAP kinase-activated protein kinase 2	Homo sapiens		 8							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348535&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064743	136355221		CHEMBL1801374				ZINC72110418	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649803	O=C1NCc2[nH]c3c(ccc4cnc(\C=C\c5cccc(CCN6CCOCC6)c5)cc34)c12	InChI=1S/C27H26N4O2/c32-27-25-22-7-5-20-16-28-21(15-23(20)26(22)30-24(25)17-29-27)6-4-18-2-1-3-19(14-18)8-9-31-10-12-33-13-11-31/h1-7,14-16,30H,8-13,17H2,(H,29,32)/b6-4+	RGWMWOOWHJUGFL-GQCTYLIASA-N	50348536	CHEMBL1801375	MAP kinase-activated protein kinase 2	Homo sapiens		 10							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348536	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348536&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064744	136355222		CHEMBL1801375				ZINC72139831	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649804	Fc1cccc(Nc2cc3c4[nH]c5CNC(=O)c5c4ccc3cn2)c1	InChI=1S/C19H13FN4O/c20-11-2-1-3-12(6-11)23-16-7-14-10(8-21-16)4-5-13-17-15(24-18(13)14)9-22-19(17)25/h1-8,24H,9H2,(H,21,23)(H,22,25)	WKRRYRSXQAPECL-UHFFFAOYSA-N	50348537	CHEMBL1801376	MAP kinase-activated protein kinase 2	Homo sapiens		 73							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348537	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348537&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676664	136355223		CHEMBL1801376				ZINC72111353	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649805	COc1ccc(cc1)-c1cc2c3[nH]c4CNC(=O)c4c3ccc2cn1	InChI=1S/C20H15N3O2/c1-25-13-5-2-11(3-6-13)16-8-15-12(9-21-16)4-7-14-18-17(23-19(14)15)10-22-20(18)24/h2-9,23H,10H2,1H3,(H,22,24)	OXLLUQHZXBFXCC-UHFFFAOYSA-N	50348538	CHEMBL1801377	MAP kinase-activated protein kinase 2	Homo sapiens		 27							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348538	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348538&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064951	136355224		CHEMBL1801377				ZINC72108938	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649806	Fc1ccccc1-c1cc2c3[nH]c4CNC(=O)c4c3ccc2cn1	InChI=1S/C19H12FN3O/c20-14-4-2-1-3-11(14)15-7-13-10(8-21-15)5-6-12-17-16(23-18(12)13)9-22-19(17)24/h1-8,23H,9H2,(H,22,24)	ZQUFPLLWPVGSOW-UHFFFAOYSA-N	50348539	CHEMBL1801378	MAP kinase-activated protein kinase 2	Homo sapiens		 85							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348539&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676665	136355225		CHEMBL1801378				ZINC72111378	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649807	FC(F)(F)c1ccccc1-c1cc2c3[nH]c4CNC(=O)c4c3ccc2cn1	InChI=1S/C20H12F3N3O/c21-20(22,23)14-4-2-1-3-11(14)15-7-13-10(8-24-15)5-6-12-17-16(26-18(12)13)9-25-19(17)27/h1-8,26H,9H2,(H,25,27)	YJWADVDRDFBIPF-UHFFFAOYSA-N	50348540	CHEMBL1801379	MAP kinase-activated protein kinase 2	Homo sapiens		 900							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348540&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25065155	136355226		CHEMBL1801379				ZINC72111511	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649808	O=C1NCc2[nH]c3c(ccc4cnc(cc34)-c3cccc(OCCN4CCOCC4)c3)c12	InChI=1S/C25H24N4O3/c30-25-23-19-5-4-17-14-26-21(13-20(17)24(19)28-22(23)15-27-25)16-2-1-3-18(12-16)32-11-8-29-6-9-31-10-7-29/h1-5,12-14,28H,6-11,15H2,(H,27,30)	TUZYUHMHEXTLNB-UHFFFAOYSA-N	50348541	CHEMBL1801380	MAP kinase-activated protein kinase 2	Homo sapiens		 32							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348541&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25065992	136355227		CHEMBL1801380				ZINC72140834	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649809	O=C1NCc2[nH]c3c(ccc4cnc(cc34)-c3cncc(OCCN4CCOCC4)c3)c12	InChI=1S/C24H23N5O3/c30-24-22-18-2-1-15-12-26-20(10-19(15)23(18)28-21(22)14-27-24)16-9-17(13-25-11-16)32-8-5-29-3-6-31-7-4-29/h1-2,9-13,28H,3-8,14H2,(H,27,30)	BEYORXSIIKUPCA-UHFFFAOYSA-N	50348542	CHEMBL1801381	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348542&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066206	136355228		CHEMBL1801381				ZINC72112356	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649810	COCCOc1cncc(c1)-c1cc2c3[nH]c4CNC(=O)c4c3ccc2cn1	InChI=1S/C21H18N4O3/c1-27-4-5-28-14-6-13(8-22-10-14)17-7-16-12(9-23-17)2-3-15-19-18(25-20(15)16)11-24-21(19)26/h2-3,6-10,25H,4-5,11H2,1H3,(H,24,26)	ZRAANXMCPIIUKV-UHFFFAOYSA-N	50348543	CHEMBL1801382	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348543&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066415	136355229		CHEMBL1801382				ZINC72112417	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649811	CN1Cc2[nH]c3c(ccc4cnc(\C=C\c5ccccc5)cc34)c2C1=O	InChI=1S/C22H17N3O/c1-25-13-19-20(22(25)26)17-10-8-15-12-23-16(11-18(15)21(17)24-19)9-7-14-5-3-2-4-6-14/h2-12,24H,13H2,1H3/b9-7+	KKQFRKTVRWJWFP-VQHVLOKHSA-N	50348544	CHEMBL1801383	MAP kinase-activated protein kinase 2	Homo sapiens		 1189							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348544&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064531	136355230		CHEMBL1801383				ZINC72140833	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649812	O=C1NCCc2[nH]c3c(ccc4cnc(\C=C\c5ccc(CN6CCOCC6)cc5)cc34)c12	InChI=1S/C27H26N4O2/c32-27-25-22-8-6-20-16-29-21(15-23(20)26(22)30-24(25)9-10-28-27)7-5-18-1-3-19(4-2-18)17-31-11-13-33-14-12-31/h1-8,15-16,30H,9-14,17H2,(H,28,32)/b7-5+	CZJALLIMKKSCNX-FNORWQNLSA-N	50348545	CHEMBL1801384	MAP kinase-activated protein kinase 2	Homo sapiens		 1							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348545&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56659490	136355231		CHEMBL1801384				ZINC72107729	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649813	O=C1NCCc2[nH]c3c(ccc4cnc(\C=C\c5cccc(CCN6CCOCC6)c5)cc34)c12	InChI=1S/C28H28N4O2/c33-28-26-23-7-5-21-18-30-22(17-24(21)27(23)31-25(26)8-10-29-28)6-4-19-2-1-3-20(16-19)9-11-32-12-14-34-15-13-32/h1-7,16-18,31H,8-15H2,(H,29,33)/b6-4+	UQQRUYAIZCVJMP-GQCTYLIASA-N	50348546	CHEMBL1801385	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348546&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25065561	136355232		CHEMBL1801385				ZINC72107490	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649814	COc1ccc(cc1F)-c1cc2c3[nH]c4CCNC(=O)c4c3ccc2cn1	InChI=1S/C21H16FN3O2/c1-27-18-5-3-11(8-15(18)22)17-9-14-12(10-24-17)2-4-13-19-16(25-20(13)14)6-7-23-21(19)26/h2-5,8-10,25H,6-7H2,1H3,(H,23,26)	HPRZHOXXSQXEIJ-UHFFFAOYSA-N	50348547	CHEMBL1801386	MAP kinase-activated protein kinase 2	Homo sapiens		 15							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348547&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066617	136355233		CHEMBL1801386				ZINC72107491	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649815	O=C1NCCc2[nH]c3c(ccc4cnc(cc34)-c3cccc(OCCN4CCOCC4)c3)c12	InChI=1S/C26H26N4O3/c31-26-24-20-5-4-18-16-28-23(15-21(18)25(20)29-22(24)6-7-27-26)17-2-1-3-19(14-17)33-13-10-30-8-11-32-12-9-30/h1-5,14-16,29H,6-13H2,(H,27,31)	FRZMEKOENCSLON-UHFFFAOYSA-N	50348548	CHEMBL1801387	MAP kinase-activated protein kinase 2	Homo sapiens		 16							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348548&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066411	136355234		CHEMBL1801387				ZINC72107167	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649816	O=C1NCCc2[nH]c3c(ccc4cnc(cc34)-c3cncc(OCCN4CCOCC4)c3)c12	InChI=1S/C25H25N5O3/c31-25-23-19-2-1-16-14-28-22(12-20(16)24(19)29-21(23)3-4-27-25)17-11-18(15-26-13-17)33-10-7-30-5-8-32-9-6-30/h1-2,11-15,29H,3-10H2,(H,27,31)	RDCWVMUIPUMVKS-UHFFFAOYSA-N	50348524	CHEMBL1801388	MAP kinase-activated protein kinase 2	Homo sapiens		 10							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348524&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066412	136355210		CHEMBL1801388				ZINC72107168	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649817	COCCOc1cncc(c1)-c1cc2c3[nH]c4CCNC(=O)c4c3ccc2cn1	InChI=1S/C22H20N4O3/c1-28-6-7-29-15-8-14(10-23-12-15)19-9-17-13(11-25-19)2-3-16-20-18(26-21(16)17)4-5-24-22(20)27/h2-3,8-12,26H,4-7H2,1H3,(H,24,27)	ZYTDQGRQFPNBGA-UHFFFAOYSA-N	50348495	CHEMBL1614995	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348495&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	HGF	3M42	25066416	136355181		CHEMBL1614995				ZINC64744267	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649818	COc1ccc(cc1F)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C21H15FN2O2/c1-26-19-7-3-11(8-15(19)22)17-9-14-12(10-23-17)2-4-13-20-16(24-21(13)14)5-6-18(20)25/h2-4,7-10,24H,5-6H2,1H3	MBAFFKJSYQWZHU-UHFFFAOYSA-N	50348525	CHEMBL1801389	MAP kinase-activated protein kinase 2	Homo sapiens		 160							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348525&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066619	136355211		CHEMBL1801389				ZINC72110147	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649819	O=C1NCCCc2[nH]c3c(ccc4cnc(\C=C\c5ccccc5)cc34)c12	InChI=1S/C23H19N3O/c27-23-21-18-11-9-16-14-25-17(10-8-15-5-2-1-3-6-15)13-19(16)22(18)26-20(21)7-4-12-24-23/h1-3,5-6,8-11,13-14,26H,4,7,12H2,(H,24,27)/b10-8+	VVVVSXKJECZPRY-CSKARUKUSA-N	50348549	CHEMBL1801390	MAP kinase-activated protein kinase 2	Homo sapiens		 116							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348549&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064324	136355235		CHEMBL1801390				ZINC72109351	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649820	O=C1NCCCc2[nH]c3c(ccc4cnc(\C=C\c5ccc(CN6CCOCC6)cc5)cc34)c12	InChI=1S/C28H28N4O2/c33-28-26-23-10-8-21-17-30-22(16-24(21)27(23)31-25(26)2-1-11-29-28)9-7-19-3-5-20(6-4-19)18-32-12-14-34-15-13-32/h3-10,16-17,31H,1-2,11-15,18H2,(H,29,33)/b9-7+	VSHQPGVRRHIKDU-VQHVLOKHSA-N	50348526	CHEMBL1801391	MAP kinase-activated protein kinase 2	Homo sapiens		 253							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348526	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348526&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25065157	136355212		CHEMBL1801391				ZINC72110193	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50669431	C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl	InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1	KTEIFNKAUNYNJU-GFCCVEGCSA-N	50306682	(R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine::3-(2,6-dichloro-3-fluorobenzyloxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine::3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)pyridin-2-amine::CHEMBL601719::CRIZOTINIB::PF-2341066::US10370379, Crizotinib::US10543199, Compound Crizotinib::US10780082, Compound Crizotinib::US11059827, Compound Crizotinib::US11517561, Compound Crizotinib::US9126941, PF-2341066::US9199944, Crizotinib::US9226923, Crizotinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50306682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50306682&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	VGH	2YFX,5AAA,5AAC,5AAB,4ANS,4ANQ,2XP2,2WGJ,3ZBF,4C9W,6IMZ	11626560	104161043	64310	CHEMBL601719	DB08700	4903		ZINC35902489	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50669443	COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1)N1CCC(CC1)N1CCN(C)CC1	InChI=1S/C30H40ClN7O3S/c1-21(2)42(39,40)28-8-6-5-7-26(28)33-29-24(31)20-32-30(35-29)34-25-10-9-23(19-27(25)41-4)37-13-11-22(12-14-37)38-17-15-36(3)16-18-38/h5-10,19-22H,11-18H2,1-4H3,(H2,32,33,34,35)	QQWUGDVOUVUTOY-UHFFFAOYSA-N	482158	BDBM50242742::TAE684	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=482158	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=482158&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			16038120	443551321							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649821	O=C1NCCCc2[nH]c3c(ccc4cnc(\C=C\c5cccc(CCN6CCOCC6)c5)cc34)c12	InChI=1S/C29H30N4O2/c34-29-27-24-9-7-22-19-31-23(18-25(22)28(24)32-26(27)5-2-11-30-29)8-6-20-3-1-4-21(17-20)10-12-33-13-15-35-16-14-33/h1,3-4,6-9,17-19,32H,2,5,10-16H2,(H,30,34)/b8-6+	USORQDCKXRFILP-SOFGYWHQSA-N	50348527	CHEMBL1801392	MAP kinase-activated protein kinase 2	Homo sapiens		 172							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348527	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348527&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56666421	136355213		CHEMBL1801392				ZINC72110194	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649822	COc1ccc(cc1)-c1cc2c3[nH]c4CCCNC(=O)c4c3ccc2cn1	InChI=1S/C22H19N3O2/c1-27-15-7-4-13(5-8-15)19-11-17-14(12-24-19)6-9-16-20-18(25-21(16)17)3-2-10-23-22(20)26/h4-9,11-12,25H,2-3,10H2,1H3,(H,23,26)	BANJKHFCWCPJKD-UHFFFAOYSA-N	50348550	CHEMBL1801091	MAP kinase-activated protein kinase 2	Homo sapiens		 72							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348550&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25064527	136355236		CHEMBL1801091				ZINC72110847	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649823	O=C1NCCCc2[nH]c3c(ccc4cnc(cc34)-c3ccccc3OCCN3CCOCC3)c12	InChI=1S/C27H28N4O3/c32-27-25-20-8-7-18-17-29-23(16-21(18)26(20)30-22(25)5-3-9-28-27)19-4-1-2-6-24(19)34-15-12-31-10-13-33-14-11-31/h1-2,4,6-8,16-17,30H,3,5,9-15H2,(H,28,32)	WJGWSDPFNWNVTL-UHFFFAOYSA-N	50348551	CHEMBL1801088	MAP kinase-activated protein kinase 2	Homo sapiens		 167							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348551&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676612	136355237		CHEMBL1801088				ZINC72109025	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649824	O=C1NCCCc2[nH]c3c(ccc4cnc(cc34)-c3cncc(OCCN4CCOCC4)c3)c12	InChI=1S/C26H27N5O3/c32-26-24-20-4-3-17-15-29-23(13-21(17)25(20)30-22(24)2-1-5-28-26)18-12-19(16-27-14-18)34-11-8-31-6-9-33-10-7-31/h3-4,12-16,30H,1-2,5-11H2,(H,28,32)	CVHRTBVPRJVKQP-UHFFFAOYSA-N	50348528	CHEMBL1801089	MAP kinase-activated protein kinase 2	Homo sapiens		 80							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348528&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066413	136355214		CHEMBL1801089				ZINC72109098	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649825	COCCOc1cncc(c1)-c1cc2c3[nH]c4CCCNC(=O)c4c3ccc2cn1	InChI=1S/C23H22N4O3/c1-29-7-8-30-16-9-15(11-24-13-16)20-10-18-14(12-26-20)4-5-17-21-19(27-22(17)18)3-2-6-25-23(21)28/h4-5,9-13,27H,2-3,6-8H2,1H3,(H,25,28)	FZASNYXRGHCWCW-UHFFFAOYSA-N	50348529	CHEMBL1801090	MAP kinase-activated protein kinase 2	Homo sapiens		 96							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348529&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066414	136355215		CHEMBL1801090				ZINC72110845	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649826	COc1ccc(cc1)-c1cc2c3[nH]c4CN(C)NC(=O)c4c3ccc2cn1	InChI=1S/C21H18N4O2/c1-25-11-18-19(21(26)24-25)15-8-5-13-10-22-17(9-16(13)20(15)23-18)12-3-6-14(27-2)7-4-12/h3-10,23H,11H2,1-2H3,(H,24,26)	WWFURUYYQWIHRV-UHFFFAOYSA-N	50348533	CHEMBL1801316	MAP kinase-activated protein kinase 2	Homo sapiens		 875							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348533&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56669835	136355219		CHEMBL1801316				ZINC72110949	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649827	Fc1ccccc1-c1cc2c3[nH]c4CNC(=O)c4c3ccc2cn1	InChI=1S/C19H12FN3O/c20-14-4-2-1-3-11(14)15-7-13-10(8-21-15)5-6-12-17-16(23-18(12)13)9-22-19(17)24/h1-8,23H,9H2,(H,22,24)	ZQUFPLLWPVGSOW-UHFFFAOYSA-N	50348539	CHEMBL1801378	MAP kinase-activated protein kinase 2	Homo sapiens		 5078							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348539	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348539&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56676665	136355225		CHEMBL1801378				ZINC72111378	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649828	O=C1NCc2[nH]c3c(ccc4cnc(cc34)-c3cccc(OCCN4CCOCC4)c3)c12	InChI=1S/C25H24N4O3/c30-25-23-19-5-4-17-14-26-21(13-20(17)24(19)28-22(23)15-27-25)16-2-1-3-18(12-16)32-11-8-29-6-9-31-10-7-29/h1-5,12-14,28H,6-11,15H2,(H,27,30)	TUZYUHMHEXTLNB-UHFFFAOYSA-N	50348541	CHEMBL1801380	MAP kinase-activated protein kinase 2	Homo sapiens		 1280							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348541&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25065992	136355227		CHEMBL1801380				ZINC72140834	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649829	O=C1NCc2[nH]c3c(ccc4cnc(cc34)-c3cncc(OCCN4CCOCC4)c3)c12	InChI=1S/C24H23N5O3/c30-24-22-18-2-1-15-12-26-20(10-19(15)23(18)28-21(22)14-27-24)16-9-17(13-25-11-16)32-8-5-29-3-6-31-7-4-29/h1-2,9-13,28H,3-8,14H2,(H,27,30)	BEYORXSIIKUPCA-UHFFFAOYSA-N	50348542	CHEMBL1801381	MAP kinase-activated protein kinase 2	Homo sapiens		 9330							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348542&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066206	136355228		CHEMBL1801381				ZINC72112356	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649830	COCCOc1cncc(c1)-c1cc2c3[nH]c4CNC(=O)c4c3ccc2cn1	InChI=1S/C21H18N4O3/c1-27-4-5-28-14-6-13(8-22-10-14)17-7-16-12(9-23-17)2-3-15-19-18(25-20(15)16)11-24-21(19)26/h2-3,6-10,25H,4-5,11H2,1H3,(H,24,26)	ZRAANXMCPIIUKV-UHFFFAOYSA-N	50348543	CHEMBL1801382	MAP kinase-activated protein kinase 2	Homo sapiens		 1680							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348543&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066415	136355229		CHEMBL1801382				ZINC72112417	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649831	COc1ccc(cc1F)-c1cc2c3[nH]c4CCNC(=O)c4c3ccc2cn1	InChI=1S/C21H16FN3O2/c1-27-18-5-3-11(8-15(18)22)17-9-14-12(10-24-17)2-4-13-19-16(25-20(13)14)6-7-23-21(19)26/h2-5,8-10,25H,6-7H2,1H3,(H,23,26)	HPRZHOXXSQXEIJ-UHFFFAOYSA-N	50348547	CHEMBL1801386	MAP kinase-activated protein kinase 2	Homo sapiens		 500							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348547&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066617	136355233		CHEMBL1801386				ZINC72107491	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649832	O=C1NCCc2[nH]c3c(ccc4cnc(cc34)-c3cccc(OCCN4CCOCC4)c3)c12	InChI=1S/C26H26N4O3/c31-26-24-20-5-4-18-16-28-23(15-21(18)25(20)29-22(24)6-7-27-26)17-2-1-3-19(14-17)33-13-10-30-8-11-32-12-9-30/h1-5,14-16,29H,6-13H2,(H,27,31)	FRZMEKOENCSLON-UHFFFAOYSA-N	50348548	CHEMBL1801387	MAP kinase-activated protein kinase 2	Homo sapiens		 1300							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348548&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066411	136355234		CHEMBL1801387				ZINC72107167	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649833	O=C1NCCc2[nH]c3c(ccc4cnc(cc34)-c3cncc(OCCN4CCOCC4)c3)c12	InChI=1S/C25H25N5O3/c31-25-23-19-2-1-16-14-28-22(12-20(16)24(19)29-21(23)3-4-27-25)17-11-18(15-26-13-17)33-10-7-30-5-8-32-9-6-30/h1-2,11-15,29H,3-10H2,(H,27,31)	RDCWVMUIPUMVKS-UHFFFAOYSA-N	50348524	CHEMBL1801388	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348524	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348524&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066412	136355210		CHEMBL1801388				ZINC72107168	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649834	COCCOc1cncc(c1)-c1cc2c3[nH]c4CCNC(=O)c4c3ccc2cn1	InChI=1S/C22H20N4O3/c1-28-6-7-29-15-8-14(10-23-12-15)19-9-17-13(11-25-19)2-3-16-20-18(26-21(16)17)4-5-24-22(20)27/h2-3,8-12,26H,4-7H2,1H3,(H,24,27)	ZYTDQGRQFPNBGA-UHFFFAOYSA-N	50348495	CHEMBL1614995	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348495&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	HGF	3M42	25066416	136355181		CHEMBL1614995				ZINC64744267	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649835	COc1ccc(cc1F)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C21H15FN2O2/c1-26-19-7-3-11(8-15(19)22)17-9-14-12(10-23-17)2-4-13-20-16(24-21(13)14)5-6-18(20)25/h2-4,7-10,24H,5-6H2,1H3	MBAFFKJSYQWZHU-UHFFFAOYSA-N	50348525	CHEMBL1801389	MAP kinase-activated protein kinase 2	Homo sapiens		 5800							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348525	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348525&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066619	136355211		CHEMBL1801389				ZINC72110147	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649836	O=C1NCCCc2[nH]c3c(ccc4cnc(cc34)-c3cncc(OCCN4CCOCC4)c3)c12	InChI=1S/C26H27N5O3/c32-26-24-20-4-3-17-15-29-23(13-21(17)25(20)30-22(24)2-1-5-28-26)18-12-19(16-27-14-18)34-11-8-31-6-9-33-10-7-31/h3-4,12-16,30H,1-2,5-11H2,(H,28,32)	CVHRTBVPRJVKQP-UHFFFAOYSA-N	50348528	CHEMBL1801089	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348528	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348528&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066413	136355214		CHEMBL1801089				ZINC72109098	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50649837	COCCOc1cncc(c1)-c1cc2c3[nH]c4CCCNC(=O)c4c3ccc2cn1	InChI=1S/C23H22N4O3/c1-29-7-8-30-16-9-15(11-24-13-16)20-10-18-14(12-26-20)4-5-17-21-19(27-22(17)18)3-2-6-25-23(21)28/h4-5,9-13,27H,2-3,6-8H2,1H3,(H,25,28)	FZASNYXRGHCWCW-UHFFFAOYSA-N	50348529	CHEMBL1801090	MAP kinase-activated protein kinase 2	Homo sapiens		 8300							ChEMBL	10.1016/j.bmcl.2010.04.024	10.7270/Q2765FNN	20594847			Revesz, L; Schlapbach, A; Aichholz, R; Feifel, R; Hawtin, S; Heng, R; Hiestand, P; Jahnke, W; Koch, G; Kroemer, M; Mobitz, H; Scheufler, C; Velcicky, J; Huppertz, C	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50348529	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50348529&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25066414	136355215		CHEMBL1801090				ZINC72110845	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50666629	Cn1cc(C2=C(C(=O)NC2=O)c2cn(C3CCN(Cc4ccccn4)CC3)c3ccccc23)c2ccccc12	InChI=1S/C32H29N5O2/c1-35-19-25(23-9-2-4-11-27(23)35)29-30(32(39)34-31(29)38)26-20-37(28-12-5-3-10-24(26)28)22-13-16-36(17-14-22)18-21-8-6-7-15-33-21/h2-12,15,19-20,22H,13-14,16-18H2,1H3,(H,34,38,39)	AXRCEOKUDYDWLF-UHFFFAOYSA-N	50128285	3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmethyl-piperidin-4-yl)-1H-indol-3-yl]-pyrrole-2,5-dione::CHEMBL300138	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50128285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50128285&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			176167	104020050		CHEMBL300138		5693		ZINC01494900	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50685156	CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1	InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)	OUSFTKFNBAZUKL-UHFFFAOYSA-N	5931	BMS-387072::CHEMBL296468::N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide::N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide::cid_3025986	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5931&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	56H	5D1J	3025986	8035540		CHEMBL296468		5670		ZINC03816409	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50679684	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50685255	Fc1ccc(C(=O)NOCC2CC2)c(Nc2ccc(I)cc2Cl)c1F	InChI=1S/C17H14ClF2IN2O2/c18-12-7-10(21)3-6-14(12)22-16-11(4-5-13(19)15(16)20)17(24)23-25-8-9-1-2-9/h3-7,9,22H,1-2,8H2,(H,23,24)	GFMMXOIFOQCCGU-UHFFFAOYSA-N	50132260	2-(2-Chloro-4-iodo-phenylamino)-N-cyclopropylmethoxy-3,4-difluoro-benzamide::2-(2-chloro-4-iodophenylamino)-N-(cyclopropylmethoxy)-3,4-difluorobenzamide::CHEMBL105442::CI-1040::PD-18435::PD-184352::US8575391, 341	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50132260	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50132260&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			6918454	104023279		CHEMBL105442		5676		ZINC01489691	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50688396	OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2F)cc1	InChI=1S/C25H15ClF2N4O2/c26-15-6-9-17-18(10-15)23(21-19(27)2-1-3-20(21)28)29-11-14-12-30-25(32-22(14)17)31-16-7-4-13(5-8-16)24(33)34/h1-10,12H,11H2,(H,33,34)(H,30,31,32)	HHFBDROWDBDFBR-UHFFFAOYSA-N	31093	4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid::4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid::BDBM31832::CHEMBL259084::MLN-8054::cid_11712649	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31093&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	ZZL	2X81,5IA1,2WTW,2WTV	11712649	252615338		CHEMBL259084		5696		ZINC18825334	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50691261	CCn1c(nc2c(ncc(OC[C@H]3CCCNC3)c12)C#CC(C)(C)O)-c1nonc1N	InChI=1S/C21H27N7O3/c1-4-28-18-15(30-12-13-6-5-9-23-10-13)11-24-14(7-8-21(2,3)29)16(18)25-20(28)17-19(22)27-31-26-17/h11,13,23,29H,4-6,9-10,12H2,1-3H3,(H2,22,27)/t13-/m0/s1	KGPGFQWBCSZGEL-ZDUSSCGKSA-N	25013	4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-piperidin-3-ylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol::GSK-690693::GSK690693::US10550114, Compound GSK690693	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25013&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	G93	3D0E,5U94	16725726	56374157				5196		ZINC34285211	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50669701	C[C@@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N	InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1	UJLAWZDWDVHWOW-YPMHNXCESA-N	50193995	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile::CHEMBL221959::CP-690550::TOFACITINIB CITRATE::Tofacitinib::Tofacitinib citrate (1)::US10112907, Example 00035::US10399979, Compound Tofacitinib::US10766894, Compound TABLE 1.20::US10875847, Compound Tofacitinib::US11078206, Example Tofacitinib::US11203595, TABLE 1.20::US11339167, Example Tofacitinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193995&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MI1	3LXK,3LXN,4OTI,3EYG,3FUP	9926791	104076339	71200	CHEMBL221959	DB08183	5677		ZINC03818808	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50677070	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50682708	CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc12	InChI=1S/C16H16N6O/c1-8(2)22-16-13(15(17)18-7-19-16)14(21-22)12-6-9-5-10(23)3-4-11(9)20-12/h3-8,20,23H,1-2H3,(H2,17,18,19)	MFAQYJIYDMLAIM-UHFFFAOYSA-N	36409	2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-ol, PP242::CID24905147::US10172858, Table 2.1::US9828378, # 1	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=36409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=36409&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P2X	4JT5	24905147	117643995						ZINC36056301	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50685368	COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)NC4=CCC(F)C=C4)cc3F)ccnc2cc1OCCCN1CCOCC1	InChI=1S/C34H36F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3,5-9,12,19-22H,2,4,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	SEJGTFPOEJWEGG-UHFFFAOYSA-N	50355504	CHEMBL1908393	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355504&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57399640	136959528		CHEMBL1908393				ZINC73140828	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50672752	C[C@@H](O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C	InChI=1S/C19H19FN4O3/c1-10-6-13-14(23-10)4-5-15(17(13)20)27-19-18-12(3)16(26-8-11(2)25)7-24(18)22-9-21-19/h4-7,9,11,23,25H,8H2,1-3H3/t11-/m1/s1	WCWUXEGQKLTGDX-LLVKDONJSA-N	50184807	(R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol::(R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yloxy)propan-2-ol::BMS-540215::CHEMBL377300	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50184807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50184807&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11234052	104069124		CHEMBL377300		5671		ZINC13684256	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50682853	Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C	InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	MVCOAUNKQVWQHZ-UHFFFAOYSA-N	13533	1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(4-methylphenyl)-3-pyrazolyl]-3-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea::1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea::3-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-1-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB 796::BIRB-796::BIRB-796, 3::CHEMBL103667::D3RKN_73::Doramapimod::US11407771, Compound 43::US8933228, BIRB 796::US9187470, 43 (BIRB-796)::US9242960, BIRB 796::US9260410, BIRB796::cid_156422::diaryl urea compound 10	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13533&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B96	4JVG,1KV2,6GTT,5N66,4TWN,3NPC,3FZS	156422	46513934		CHEMBL103667	DB03044	5668		ZINC24044436	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50685483	COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1	InChI=1S/C24H24N4O5S/c1-14(23-26-9-10-34-23)27-24(29)28-17-6-5-15(11-20(17)30-2)33-19-7-8-25-18-13-22(32-4)21(31-3)12-16(18)19/h5-14H,1-4H3,(H2,27,28,29)	SHPFDGWALWEPGS-UHFFFAOYSA-N	50355494	CHEMBL1908396	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9869779	136959518		CHEMBL1908396				ZINC13975055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50677260	CN(C)C\C=C\C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O[C@H]1CCOC1	InChI=1S/C24H25ClFN5O3/c1-31(2)8-3-4-23(32)30-21-11-17-20(12-22(21)34-16-7-9-33-13-16)27-14-28-24(17)29-15-5-6-19(26)18(25)10-15/h3-6,10-12,14,16H,7-9,13H2,1-2H3,(H,30,32)(H,27,28,29)/b4-3+/t16-/m0/s1	ULXXDDBFHOBEHA-CWDCEQMOSA-N	50322823	(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide::AFATINIB::CHEMBL1173655::US10085983, Compound BIBW2992::US10196365, Afatinib::US10435400, Compound BIBW2992::US9388170, Afatinib::US9890168, Compound BIBW2992::WO2022090481, Example afatinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50322823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50322823&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	0WM	4G5J	10184653	104144352	61390	CHEMBL1173655	DB08916	5667		ZINC03976838	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50691506	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50670015	CNC(=O)c1c(F)cccc1Nc1nc(Nc2cc3N(CCc3cc2OC)C(=O)CN(C)C)nc2[nH]ccc12	InChI=1S/C27H29FN8O3/c1-29-26(38)23-17(28)6-5-7-18(23)31-25-16-8-10-30-24(16)33-27(34-25)32-19-13-20-15(12-21(19)39-4)9-11-36(20)22(37)14-35(2)3/h5-8,10,12-13H,9,11,14H2,1-4H3,(H,29,38)(H3,30,31,32,33,34)	HZTYDQRUAWIZRE-UHFFFAOYSA-N	27817	2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-dihydro-1H-indol-6-yl}amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino}-6-fluoro-N-methylbenzamide::pyrrolo[2,3-d]pyrimidine deriv., 40	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27817&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25182616	57560329				5683		ZINC43202844	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50671402	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1	InChI=1S/C23H27FN4O4/c1-13-20(10-18-17-9-15(24)3-4-19(17)27-22(18)30)26-14(2)21(13)23(31)25-11-16(29)12-28-5-7-32-8-6-28/h3-4,9-10,16,26,29H,5-8,11-12H2,1-2H3,(H,25,31)(H,27,30)/b18-10-/t16-/m0/s1	CTNPALGJUAXMMC-PMFHANACSA-N	31095	5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[(2S)-3-morpholin-4-yl-2-oxidanyl-propyl]-1H-pyrrole-3-carboxamide::5-[(Z)-(5-fluoro-2-keto-indolin-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholino-propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU-14813::cid_10138259	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31095&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10138259	252615339						ZINC18825344	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50675761	CN(C)CC(=O)N1CCC(CC1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1	InChI=1S/C26H32N6O2/c1-31(2)17-24(33)32-12-10-18(11-13-32)20-8-9-23(22(14-20)19-6-4-3-5-7-19)30-26(34)25-28-16-21(15-27)29-25/h6,8-9,14,16,18H,3-5,7,10-13,17H2,1-2H3,(H,28,29)(H,30,34)	GUBJNPWVIUFSTR-UHFFFAOYSA-N	50355499	CHEMBL1908395::CHEMBL1908842	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355499&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11676971	136959523		CHEMBL1908842CHEMBL1908395				ZINC38226716	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50675788	Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1	InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2	TUVCWJQQGGETHL-UHFFFAOYSA-N	25045	3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol::3-(4-morpholin-4-ylpyrido[3 ,2 :4,5]furo[3,2-d]pyrimidin-2-yl)phenol::3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol::3-[4-(4-morpholinyl)-2-pyrido[2,3]furo[2,4-b]pyrimidinyl]phenol::3-[6-(morpholin-4-yl)-8-oxa-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-4-yl]phenol::CHEMBL538346::PI-103::US9637488, PI-103::cid_9884685::mTOR Inhibitor, PI103::pyridofuropyrimidine derivative, 2	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25045&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	X6K	2X6K,4L23,4JT6	9884685	56374189		CHEMBL538346		5701		ZINC03963016	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50677301	Clc1cccc(Cl)c1C(=O)Nc1cn[nH]c1C(=O)NC1CCNCC1	InChI=1S/C16H17Cl2N5O2/c17-10-2-1-3-11(18)13(10)15(24)22-12-8-20-23-14(12)16(25)21-9-4-6-19-7-5-9/h1-3,8-9,19H,4-7H2,(H,20,23)(H,21,25)(H,22,24)	OVPNQJVDAFNBDN-UHFFFAOYSA-N	24654	4-N-(2,6-dichlorobenzene)-3-N-(piperidin-4-yl)-1H-pyrazole-3,4-diamido::AT7519::JMC514986 Compound 33::pyrazole diamide, 33	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24654	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24654&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	LZE	7AGA,2VU3	11338033	56269605				5662		ZINC16052857	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50680079	C[C@@H](Oc1cc(sc1C(N)=O)-n1cnc2ccc(CN3CCN(C)CC3)cc12)c1ccccc1C(F)(F)F	InChI=1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28,29)30)37-23-14-24(38-25(23)26(31)36)35-16-32-21-8-7-18(13-22(21)35)15-34-11-9-33(2)10-12-34/h3-8,13-14,16-17H,9-12,15H2,1-2H3,(H2,31,36)/t17-/m1/s1	ZHJGWYRLJUCMRT-QGZVFWFLSA-N	50355500	CHEMBL1908394::US9695172, GSK461364	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355500&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			15983966	136959524		CHEMBL1908394				ZINC43154472	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50680110	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50681685	CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1	InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)	GCIKSSRWRFVXBI-UHFFFAOYSA-N	13534	CHEMBL572878::N-[4-({4-[(3-methyl-1H-pyrazol-5-yl)amino]-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl}sulfanyl)phenyl]cyclopropanecarboxamide::N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]thio]phenyl]cyclopropanecarboxamide::VX-680::VX680::cyclopropane carboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)-pyrimidin-2ylsulphanyl]-phenyl}-amide	MAP kinase-activated protein kinase 2	Homo sapiens			 3800						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13534&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	VX6	2F4J,6GR9,6BRJ,3E5A,4ZOG,4B8M,5WNM,3AMB,4JBQ,4AF3,2XYN	5494449	46513935		CHEMBL572878		5718		ZINC03820040	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50690336	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C	InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	WINHZLLDWRZWRT-ATVHPVEESA-N	4814	CHEMBL535::N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU11248::SUNITINIB::SUNITINIB MALATE::US10464902, Sunitinib::US9163010, Sunitinib::US9914707, SU11248	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4814&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B49	6NG0,4KS8,3G0F,3G0E,2Y7J,6JOK,6M11,3MIY,3TI1,4QMZ,6V0X,6NFZ,6NFY,4AGD	5329102	8034462	38940	CHEMBL535	DB01268	5713		ZINC03964325	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50677505	Cn1c(Nc2ccc(cc2)C(F)(F)F)nc2cc(Oc3ccnc(c3)-c3ncc([nH]3)C(F)(F)F)ccc12	InChI=1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,35)(H,33,34)	YABJJWZLRMPFSI-UHFFFAOYSA-N	31088	1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine::1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-2-benzimidazolamine::CHIR-265::[1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridyl]oxy]benzimidazol-2-yl]-[4-(trifluoromethyl)phenyl]amine::cid_11656518	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31088	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31088&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	55J	5CT7	11656518	252615336				5674		ZINC18710085	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50678993	COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c1cccnc1C	InChI=1S/C19H15ClN4O2/c1-10-11(4-3-6-22-10)19(25)24-17-16-13(8-14(20)18(17)26-2)12-5-7-21-9-15(12)23-16/h3-9,23H,1-2H3,(H,24,25)	ZNOLRTPMNMPLHY-UHFFFAOYSA-N	50309910	CHEMBL608154::ML-120B::N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50309910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50309910&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9929127	104164271		CHEMBL608154		5694		ZINC06717113	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50684559	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1	InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1	OYONTEXKYJZFHA-SSHUPFPWSA-N	50242737	(R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimethyl-4-(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-1H-pyrrol-2-yl)methylene)indolin-2-one::CHEMBL450786::PHA-665752::TCMDC-125885	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242737&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10461815	104099202		CHEMBL450786		5700		ZINC03938668	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50691896	Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(cc12)C(=O)NOCCO	InChI=1S/C17H15BrClFN4O3/c1-24-8-21-16-13(24)7-10(17(26)23-27-5-4-25)15(14(16)20)22-12-3-2-9(18)6-11(12)19/h2-3,6-8,22,25H,4-5H2,1H3,(H,23,26)	CYOHGALHFOKKQC-UHFFFAOYSA-N	50355497	AZD-6244::CHEMBL1614701	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355497&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	3EW	4U7Z,7JUZ,7JUT,7M0T	10127622	136959521		CHEMBL1614701				ZINC31773258	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50673314	COc1ccc(F)c(F)c1C(=O)c1cnc(NC2CCN(CC2)S(C)(=O)=O)nc1N	InChI=1S/C18H21F2N5O4S/c1-29-13-4-3-12(19)15(20)14(13)16(26)11-9-22-18(24-17(11)21)23-10-5-7-25(8-6-10)30(2,27)28/h3-4,9-10H,5-8H2,1-2H3,(H3,21,22,23,24)	JRNJNYBQQYBCLE-UHFFFAOYSA-N	12621	2,4-Diamino-5-ketopyrimidine 39::5-[(2,3-difluoro-6-methoxyphenyl)carbonyl]-2-N-(1-methanesulfonylpiperidin-4-yl)pyrimidine-2,4-diamine::R547::[4-Amino-2-(1-methanesulfonylpiperidin-4-ylamino)pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=12621	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=12621&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	LIA	2FVD	6918852	46513075			DB08094	5707		ZINC13983251	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50677610	Nc1nc(N)c2nc(-c3cccc(O)c3)c(nc2n1)-c1cccc(O)c1	InChI=1S/C18H14N6O2/c19-16-15-17(24-18(20)23-16)22-14(10-4-2-6-12(26)8-10)13(21-15)9-3-1-5-11(25)7-9/h1-8,25-26H,(H4,19,20,22,23,24)	UJIAQDJKSXQLIT-UHFFFAOYSA-N	25084	3-[2,4-diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol::JMC504279 Compound 6::TG100-115	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25084	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25084&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B6J	5WNK	10427712	56374226				5715		ZINC06718666	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50679030	CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1	InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	KTUFNOKKBVMGRW-UHFFFAOYSA-N	13530	4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide::CHEMBL941::Gleevec::Imatinib::Imatinib, 21::N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide::STI-571::STI571::US10906896, Cpd imatinib::US11649218, Example Imatinib::US9255107, Imatinib::cid_5291::imatinib-CD3::med.21724, Compound 6	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13530&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	STI	6HD6,6HD4,2HYY,4BKJ,2PL0,3GVU,6NPU,6NPV,6NPE,4CSV,3MS9,3MSS,4R7I,7N9G,2OIQ,1IEP,1XBB,3HEC,1T46,3FW1,3PYY,6VXH,6JOL,3K5V,5MQT,3OEZ,6KTN,1OPJ	5291	46513933	45783	CHEMBL941	DB00619	5687		ZINC19632618	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50676264	CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O	InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)	PIQCTGMSNWUMAF-UHFFFAOYSA-N	25118	(3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,3-dihydrobenzimidazol-2-ylidene]carbostyril::4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one::CHEMBL522892::CHIR-258	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25118&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9886808	56374260		CHEMBL522892		5962		ZINC03816310	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50676371	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50679110	Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1	InChI=1S/C22H22N4O/c1-15-21-11-17(7-8-22(21)26-25-15)18-10-20(13-24-12-18)27-14-19(23)9-16-5-3-2-4-6-16/h2-8,10-13,19H,9,14,23H2,1H3,(H,25,26)/t19-/m0/s1	BPNUQXPIQBZCMR-IBGZPJMESA-N	15138	5-indazolyl pyridine 11g::5-{5-[(2S)-2-amino-3-phenylpropoxy]pyridin-3-yl}-3-methyl-1H-indazole::A-674563::Biochemistry 469551 Compound 11::indazole-pyridine, 7	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15138&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	SS3	2UZT	11314340	46515449			DB08568	5655		ZINC16052569	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50683481	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50690739	CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)-c2cccc3[nH]ncc23)CC1	InChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)	LHNIIDJUOCFXAP-UHFFFAOYSA-N	25028	4-[2-(1H-indazol-4-yl)-6-[(4-methanesulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine::GDC-0941::GDC0941::US10112932, pictilisib::US10851091, Compound pictilisib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25028&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	GD9	3DBS,2Y3A,2WXP	17755052	56374172	65326					ZINC16052714	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50679209	CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C30H29ClN6O3/c1-4-39-28-16-25-23(15-26(28)36-29(38)9-7-13-37(2)3)30(20(17-32)18-34-25)35-21-10-11-27(24(31)14-21)40-19-22-8-5-6-12-33-22/h5-12,14-16,18H,4,13,19H2,1-3H3,(H,34,35)(H,36,38)/b9-7+	JWNPDZNEKVCWMY-VQHVLOKHSA-N	50161957	4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide::CHEMBL180022::HKI-272::N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide::N-(4-(3-chloro-4-(pyridin-2-ylmethoxy)phenylamino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)butanamide::NERATINIB::US10822334, Compound Neratinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50161957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50161957&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9915743	104048227		CHEMBL180022		5686		ZINC03916214	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50680610	CNC(=O)c1ccccc1Sc1ccc2c(\C=C\c3ccccn3)n[nH]c2c1	InChI=1S/C22H18N4OS/c1-23-22(27)18-7-2-3-8-21(18)28-16-10-11-17-19(25-26-20(17)14-16)12-9-15-6-4-5-13-24-15/h2-14H,1H3,(H,23,27)(H,25,26)/b12-9+	RITAVMQDGBJQJZ-FMIVXFBMSA-N	25117	AG-013736::AXITINIB::N-methyl-2-({3-[(E)-2-(pyridin-2-yl)ethenyl]-1H-indazol-6-yl}sulfanyl)benzamide::US10464902, Axitinib::US9205078, Axitinib ::US9617222, Compound A	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25117&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			6450551	56374259	66910			5659		ZINC03816287	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50683642	CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(OCCN4CCOCC4)ccc32)no1	InChI=1S/C29H32N6O4S/c1-29(2,3)25-17-26(33-39-25)32-27(36)30-20-6-4-19(5-7-20)22-18-35-23-9-8-21(16-24(23)40-28(35)31-22)38-15-12-34-10-13-37-14-11-34/h4-9,16-18H,10-15H2,1-3H3,(H2,30,32,33,36)	CVWXJKQAOSCOAB-UHFFFAOYSA-N	50300690	1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea::AC 010220::AC 220::AC-220::AC010220::AC220::ASP-2689::CHEMBL576982::N-(5-tert-Butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea::Quizartinib::Quizartinib (AC220)::US10266535, Compound AC220::US11542261, Compound quizartinib::US9216997, Quizartinib (positive compound)	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50300690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50300690&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P30	4XUF,4RT7	24889392	104155051		CHEMBL576982		5658		ZINC43204002	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50687989	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50692234	OCCn1cc(c(n1)-c1ccncc1)-c1ccc2C(CCc2c1)N=O	InChI=1S/C19H18N4O2/c24-10-9-23-12-17(19(21-23)13-5-7-20-8-6-13)15-1-3-16-14(11-15)2-4-18(16)22-25/h1,3,5-8,11-12,18,24H,2,4,9-10H2	RIGIGAFKKVBACY-UHFFFAOYSA-N	25628	2-{4-[(1Z)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethan-1-ol::AR00341677::CHEMBL525191::GDC-0879	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25628	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25628&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91448975	56412918		CHEMBL525191				ZINC34640412	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50680763	CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1	InChI=1S/C21H16Cl2N4OS/c1-27-19-12(9-15(20(27)28)18-16(22)7-4-8-17(18)23)11-24-21(26-19)25-13-5-3-6-14(10-13)29-2/h3-11H,1-2H3,(H,24,25,26)	VAARYSWULJUGST-UHFFFAOYSA-N	6568	6-(2,6-dichlorophenyl)-8-methyl-2-{[3-(methylsulfanyl)phenyl]amino}-7H,8H-pyrido[2,3-d]pyrimidin-7-one::CHEMBL386051::PD-173955::PD173955::US11136333, Compound PD173955	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6568&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P17	1M52,5IA3	447077	8036145	49791	CHEMBL386051	DB02567	5699		ZINC02047743	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50682336	Fc1ccc(Sc2ccc3c(-c4c(Cl)cccc4Cl)c(=O)ncn3n2)c(F)c1	InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H	VEPKQEUBKLEPRA-UHFFFAOYSA-N	15244	5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-a]pyridazin-6-one::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6-pyrimido[1,6-b]pyridazinone::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]pyrimido[1,6-b]pyridazin-6-one::5-(2,6-dichlorophenyl)-9-(2,4-difluorophenyl)sulfanyl-1,3,10-triazabicyclo[4.4.0]deca-2,5,7,9-tetraen-4-one::5-[2,6-bis(chloranyl)phenyl]-2-[2,4-bis(fluoranyl)phenyl]sulfanyl-pyrimido[1,6-b]pyridazin-6-one::VX-745::VX745::cid_3038525	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15244&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	52P	3ZSI,3HP5,3FC1	3038525	46515551			DB07138			ZINC13493055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50672222	N#CC[C@H](C1CCCC1)n1cc(cn1)-c1ncnc2[nH]ccc12	InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1	HFNKQEVNSGCOJV-OAHLLOKOSA-N	50355501	INCB-018424::RUXOLITINIB::RUXOLITINIB PHOSPHATE::US10112907, Example 00016::US10766894, Compound TABLE 1.1::US10875847, Compound JAKAFI::US11203595, TABLE 1.1::US11279703, TABLE 6.147	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355501&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	RXT	6VNK,6WTN,6VGL,4U5J,7F3G	25126798	136959525	66919		DB08877			ZINC43207851	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50689616	CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1	InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32)	WJEOLQLKVOPQFV-UHFFFAOYSA-N	50355495	CHEMBL1908391	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355495&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	G65	7TVX,5MQL,7JU7	10074640	136959519	63450	CHEMBL1908391				ZINC34177219	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50695442	COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1	InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24)	MYQAUKPBNJWPIE-UHFFFAOYSA-N	32362	5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine::GW-2580::[2-amino-5-(3-methoxy-4-p-anisyloxy-benzyl)pyrimidin-4-yl]amine::cid_11617559	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32362&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MUJ	4AT5	11617559	252615797				5685		ZINC13985942	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50696819	Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1	InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)	MPVGZUGXCQEXTM-UHFFFAOYSA-N	21079	1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea::1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea::1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluoranyl-5-methyl-phenyl)urea::3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea::ABT-869::Aminoindazole, 3::CHEMBL223360::cid_11485656	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21079	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21079&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11485656	49689152		CHEMBL223360		5657		ZINC06718813	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50692717	COc1cc(Nc2ncc(F)c(Nc3ccc4OC(C)(C)C(=O)Nc4n3)n2)cc(OC)c1OC	InChI=1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,28,29,30)	NHHQJBCNYHBUSI-UHFFFAOYSA-N	60665	BDBM50249542::US9145414, R406::US9212178, R406	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=60665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=60665&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	585	3PIY,3FQS	11213558	316921779			DB07159			ZINC13555629	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50695535	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50695568	Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1	InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)	YCOYDOIWSSHVCK-UHFFFAOYSA-N	4851	(4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine::(A) PTK787::CGP 79787::CHEMBL101253::CHEMBL75232::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-1-phthalazinamine::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine::PTK-787::PTK787::ZK222584::cid_151194	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4851&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			151194	8034494		CHEMBL75232CHEMBL101253	DB04879	6052		ZINC00007460	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709348	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C27H25N5O2/c33-25(20-6-5-17-3-1-2-4-18(17)13-20)32-23-14-19(7-10-29-23)22-15-21-24(31-22)27(16-30-26(21)34)8-11-28-12-9-27/h1-7,10,13-15,28,31H,8-9,11-12,16H2,(H,30,34)(H,29,32,33)	DWRIDLORHRQUGO-UHFFFAOYSA-N	50360547	CHEMBL1933164	MAP kinase-activated protein kinase 2	Homo sapiens				 280					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360547&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835139	136964609		CHEMBL1933164				ZINC73223479	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709349	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C25H27N5O2/c1-15-3-4-18(11-16(15)2)23(31)30-21-12-17(5-8-27-21)20-13-19-22(29-20)25(14-28-24(19)32)6-9-26-10-7-25/h3-5,8,11-13,26,29H,6-7,9-10,14H2,1-2H3,(H,28,32)(H,27,30,31)	JLSAYGNBEXSZKV-UHFFFAOYSA-N	50360548	CHEMBL1933162	MAP kinase-activated protein kinase 2	Homo sapiens				 350					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360548&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835137	136964610		CHEMBL1933162				ZINC73223475	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709350	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-10-16(26-19(14)22(11-25-21)4-7-23-8-5-22)15-3-6-24-20(27-15)13-1-2-17-18(9-13)30-12-29-17/h1-3,6,9-10,23,26H,4-5,7-8,11-12H2,(H,25,28)	QSDGMDKMSSYMKU-UHFFFAOYSA-N	50344696	2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1738702	MAP kinase-activated protein kinase 2	Homo sapiens				 620					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344696&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	05B	3R1N,3R2B	53326866	131347632		CHEMBL1738702				ZINC66156777	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709351	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O)c1ccccn1	InChI=1S/C21H20N6O2/c28-19-14-10-16(26-18(14)21(12-25-19)5-8-22-11-21)13-4-7-24-17(9-13)27-20(29)15-3-1-2-6-23-15/h1-4,6-7,9-10,22,26H,5,8,11-12H2,(H,25,28)(H,24,27,29)	KUHJGHADZLHBNB-UHFFFAOYSA-N	50360549	CHEMBL1933193	MAP kinase-activated protein kinase 2	Homo sapiens				 4.1					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360549&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57396966	136964611		CHEMBL1933193				ZINC73390355	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709352	FC(F)(F)Oc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C23H20F3N5O3/c24-23(25,26)34-15-3-1-2-14(8-15)20(32)31-18-9-13(4-6-28-18)17-10-16-19(30-17)22(5-7-27-11-22)12-29-21(16)33/h1-4,6,8-10,27,30H,5,7,11-12H2,(H,29,33)(H,28,31,32)	FTVRHNVXLBYVGQ-UHFFFAOYSA-N	50360550	CHEMBL1933192	MAP kinase-activated protein kinase 2	Homo sapiens				 1.6					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360550&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398710	136964612		CHEMBL1933192				ZINC73223536	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709353	Fc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C22H20FN5O2/c23-15-3-1-2-14(8-15)20(29)28-18-9-13(4-6-25-18)17-10-16-19(27-17)22(5-7-24-11-22)12-26-21(16)30/h1-4,6,8-10,24,27H,5,7,11-12H2,(H,26,30)(H,25,28,29)	VZMUGQWLTZKXEN-UHFFFAOYSA-N	50360551	CHEMBL1933191	MAP kinase-activated protein kinase 2	Homo sapiens				 1.9					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360551&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395186	136964613		CHEMBL1933191				ZINC73223533	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709354	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C22H20FN5O2/c23-15-3-1-13(2-4-15)20(29)28-18-9-14(5-7-25-18)17-10-16-19(27-17)22(6-8-24-11-22)12-26-21(16)30/h1-5,7,9-10,24,27H,6,8,11-12H2,(H,26,30)(H,25,28,29)	WAHGXXOQYXBZOI-UHFFFAOYSA-N	50360552	CHEMBL1933190	MAP kinase-activated protein kinase 2	Homo sapiens				 1.3					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360552&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57396965	136964614		CHEMBL1933190				ZINC73223528	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709355	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C26H23N5O2/c32-24(19-6-5-16-3-1-2-4-17(16)11-19)31-22-12-18(7-9-28-22)21-13-20-23(30-21)26(8-10-27-14-26)15-29-25(20)33/h1-7,9,11-13,27,30H,8,10,14-15H2,(H,29,33)(H,28,31,32)	OINVDTDMPCVMLA-UHFFFAOYSA-N	50360553	CHEMBL1933189	MAP kinase-activated protein kinase 2	Homo sapiens				 0.62					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360553&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57402183	136964615		CHEMBL1933189				ZINC73240063	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709356	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C24H25N5O2/c1-14-3-4-17(9-15(14)2)22(30)29-20-10-16(5-7-26-20)19-11-18-21(28-19)24(6-8-25-12-24)13-27-23(18)31/h3-5,7,9-11,25,28H,6,8,12-13H2,1-2H3,(H,27,31)(H,26,29,30)	SWTKULKSQOJRAV-UHFFFAOYSA-N	50360554	CHEMBL1933188	MAP kinase-activated protein kinase 2	Homo sapiens				 0.71					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360554&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400386	136964616		CHEMBL1933188				ZINC73240299	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709357	FC(F)(F)c1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H22F3N5O2/c25-24(26,27)16-4-1-3-15(9-16)21(33)32-19-10-14(5-8-29-19)18-11-17-20(31-18)23(13-30-22(17)34)6-2-7-28-12-23/h1,3-5,8-11,28,31H,2,6-7,12-13H2,(H,30,34)(H,29,32,33)	FEVPBNYNYKIJAR-UHFFFAOYSA-N	50360555	CHEMBL1933187	MAP kinase-activated protein kinase 2	Homo sapiens				 3.3					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360555&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	I85	3SHE	57395185	136964617		CHEMBL1933187				ZINC73240294	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709358	Fc1cc(F)cc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H21F2N5O2/c24-15-6-14(7-16(25)9-15)21(31)30-19-8-13(2-5-27-19)18-10-17-20(29-18)23(12-28-22(17)32)3-1-4-26-11-23/h2,5-10,26,29H,1,3-4,11-12H2,(H,28,32)(H,27,30,31)	DCOPJWXPAYWITJ-UHFFFAOYSA-N	50360556	CHEMBL1933186	MAP kinase-activated protein kinase 2	Homo sapiens				 2.5					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360556&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391727	136964618		CHEMBL1933186				ZINC73240285	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709359	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1ccccn1	InChI=1S/C22H22N6O2/c29-20-15-11-17(27-19(15)22(13-26-20)6-3-7-23-12-22)14-5-9-25-18(10-14)28-21(30)16-4-1-2-8-24-16/h1-2,4-5,8-11,23,27H,3,6-7,12-13H2,(H,26,29)(H,25,28,30)	BPABKQIJZOOSGR-UHFFFAOYSA-N	50360557	CHEMBL1933185	MAP kinase-activated protein kinase 2	Homo sapiens				 4.2					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360557&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398709	136964619		CHEMBL1933185				ZINC73240280	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709360	FC(F)(F)c1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H22F3N5O2/c25-24(26,27)16-4-2-14(3-5-16)21(33)32-19-10-15(6-9-29-19)18-11-17-20(31-18)23(13-30-22(17)34)7-1-8-28-12-23/h2-6,9-11,28,31H,1,7-8,12-13H2,(H,30,34)(H,29,32,33)	NMFTXZYZNCQGNR-UHFFFAOYSA-N	50360558	CHEMBL1933184	MAP kinase-activated protein kinase 2	Homo sapiens				 9.1					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360558&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400385	136964620		CHEMBL1933184				ZINC82158179	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709361	FC(F)(F)Oc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H22F3N5O3/c25-24(26,27)35-16-4-1-3-15(9-16)21(33)32-19-10-14(5-8-29-19)18-11-17-20(31-18)23(13-30-22(17)34)6-2-7-28-12-23/h1,3-5,8-11,28,31H,2,6-7,12-13H2,(H,30,34)(H,29,32,33)	LRSZNMCVFHOKHV-UHFFFAOYSA-N	50360559	CHEMBL1933183	MAP kinase-activated protein kinase 2	Homo sapiens				 11					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360559&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400384	136964621		CHEMBL1933183				ZINC82157891	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709362	Fc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-4-1-3-15(9-16)21(30)29-19-10-14(5-8-26-19)18-11-17-20(28-18)23(13-27-22(17)31)6-2-7-25-12-23/h1,3-5,8-11,25,28H,2,6-7,12-13H2,(H,27,31)(H,26,29,30)	KKJUHFUYRZTCSN-UHFFFAOYSA-N	50360560	CHEMBL1933182	MAP kinase-activated protein kinase 2	Homo sapiens				 6.2					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360560&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403941	136964622		CHEMBL1933182				ZINC73219236	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50696983	CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1	InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)	CUIHSIWYWATEQL-UHFFFAOYSA-N	26474	5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzene-1-sulfonamide::GW-786034::JMC514632 Compound 13::Pazopanib::cid_10113978	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26474&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10113978	56464911	71219		DB06589	5698		ZINC11617039	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50703207	[O-][n+]1ccc2c(ccnc2c1-c1c(Cl)cccc1Cl)-c1ccc(F)cc1Cl	InChI=1S/C20H10Cl3FN2O/c21-15-2-1-3-16(22)18(15)20-19-14(7-9-26(20)27)12(6-8-25-19)13-5-4-11(24)10-17(13)23/h1-10H	AUZOBOALIFKXNA-UHFFFAOYSA-N	50357884	CHEMBL1916359	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm200975u	10.7270/Q2MW2HKR	21999461			Lumeras, W; Vidal, L; Vidal, B; Balague, C; Orellana, A; Maldonado, M; Dominguez, M; Segarra, V; Caturla, F	Rh&#244;ne-Poulenc Rorer	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50357884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50357884&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24896769	136961908		CHEMBL1916359				ZINC73162320	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709363	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-4-2-14(3-5-16)21(30)29-19-10-15(6-9-26-19)18-11-17-20(28-18)23(13-27-22(17)31)7-1-8-25-12-23/h2-6,9-11,25,28H,1,7-8,12-13H2,(H,27,31)(H,26,29,30)	UDOBRIMHNLEDHZ-UHFFFAOYSA-N	50360561	CHEMBL1933181	MAP kinase-activated protein kinase 2	Homo sapiens				 31					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400383	136964623		CHEMBL1933181				ZINC73219230	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709364	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-4-2-14(3-5-16)21(30)29-19-10-15(6-9-26-19)18-11-17-20(28-18)23(13-27-22(17)31)7-1-8-25-12-23/h2-6,9-11,25,28H,1,7-8,12-13H2,(H,27,31)(H,26,29,30)	UDOBRIMHNLEDHZ-UHFFFAOYSA-N	50360561	CHEMBL1933181	MAP kinase-activated protein kinase 2	Homo sapiens				 31.0					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400383	136964623		CHEMBL1933181				ZINC73219230	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709365	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-4-2-14(3-5-16)21(30)29-19-10-15(6-9-26-19)18-11-17-20(28-18)23(13-27-22(17)31)7-1-8-25-12-23/h2-6,9-11,25,28H,1,7-8,12-13H2,(H,27,31)(H,26,29,30)	UDOBRIMHNLEDHZ-UHFFFAOYSA-N	50360561	CHEMBL1933181	MAP kinase-activated protein kinase 2	Homo sapiens				 2.40					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400383	136964623		CHEMBL1933181				ZINC73219230	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709366	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1cccc2ccccc12	InChI=1S/C27H25N5O2/c33-25-21-14-22(31-24(21)27(16-30-25)10-4-11-28-15-27)18-9-12-29-23(13-18)32-26(34)20-8-3-6-17-5-1-2-7-19(17)20/h1-3,5-9,12-14,28,31H,4,10-11,15-16H2,(H,30,33)(H,29,32,34)	BQTRFPKZTXCUPV-UHFFFAOYSA-N	50360562	CHEMBL1933180	MAP kinase-activated protein kinase 2	Homo sapiens				 5.1					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360562&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393464	136964624		CHEMBL1933180				ZINC73219225	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709367	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C27H25N5O2/c33-25(20-7-6-17-4-1-2-5-18(17)12-20)32-23-13-19(8-11-29-23)22-14-21-24(31-22)27(16-30-26(21)34)9-3-10-28-15-27/h1-2,4-8,11-14,28,31H,3,9-10,15-16H2,(H,30,34)(H,29,32,33)	YUIHVDXPZJATDG-UHFFFAOYSA-N	50360563	CHEMBL1933179	MAP kinase-activated protein kinase 2	Homo sapiens				 129					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360563&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403940	136964625		CHEMBL1933179				ZINC73240489	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709368	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O)c1ccccn1	InChI=1S/C21H20N6O2/c28-19-14-10-16(26-18(14)21(12-25-19)5-8-22-11-21)13-4-7-24-17(9-13)27-20(29)15-3-1-2-6-23-15/h1-4,6-7,9-10,22,26H,5,8,11-12H2,(H,25,28)(H,24,27,29)	KUHJGHADZLHBNB-UHFFFAOYSA-N	50360549	CHEMBL1933193	MAP kinase-activated protein kinase 2	Homo sapiens				 660					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360549&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57396966	136964611		CHEMBL1933193				ZINC73390355	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709369	FC(F)(F)Oc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C23H20F3N5O3/c24-23(25,26)34-15-3-1-2-14(8-15)20(32)31-18-9-13(4-6-28-18)17-10-16-19(30-17)22(5-7-27-11-22)12-29-21(16)33/h1-4,6,8-10,27,30H,5,7,11-12H2,(H,29,33)(H,28,31,32)	FTVRHNVXLBYVGQ-UHFFFAOYSA-N	50360550	CHEMBL1933192	MAP kinase-activated protein kinase 2	Homo sapiens				 400					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360550&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398710	136964612		CHEMBL1933192				ZINC73223536	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709370	Fc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C22H20FN5O2/c23-15-3-1-2-14(8-15)20(29)28-18-9-13(4-6-25-18)17-10-16-19(27-17)22(5-7-24-11-22)12-26-21(16)30/h1-4,6,8-10,24,27H,5,7,11-12H2,(H,26,30)(H,25,28,29)	VZMUGQWLTZKXEN-UHFFFAOYSA-N	50360551	CHEMBL1933191	MAP kinase-activated protein kinase 2	Homo sapiens				 480					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360551&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395186	136964613		CHEMBL1933191				ZINC73223533	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709371	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C22H20FN5O2/c23-15-3-1-13(2-4-15)20(29)28-18-9-14(5-7-25-18)17-10-16-19(27-17)22(6-8-24-11-22)12-26-21(16)30/h1-5,7,9-10,24,27H,6,8,11-12H2,(H,26,30)(H,25,28,29)	WAHGXXOQYXBZOI-UHFFFAOYSA-N	50360552	CHEMBL1933190	MAP kinase-activated protein kinase 2	Homo sapiens				 840					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360552&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57396965	136964614		CHEMBL1933190				ZINC73223528	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709372	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C26H23N5O2/c32-24(19-6-5-16-3-1-2-4-17(16)11-19)31-22-12-18(7-9-28-22)21-13-20-23(30-21)26(8-10-27-14-26)15-29-25(20)33/h1-7,9,11-13,27,30H,8,10,14-15H2,(H,29,33)(H,28,31,32)	OINVDTDMPCVMLA-UHFFFAOYSA-N	50360553	CHEMBL1933189	MAP kinase-activated protein kinase 2	Homo sapiens				 390					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360553&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57402183	136964615		CHEMBL1933189				ZINC73240063	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709373	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNC1)CNC2=O	InChI=1S/C24H25N5O2/c1-14-3-4-17(9-15(14)2)22(30)29-20-10-16(5-7-26-20)19-11-18-21(28-19)24(6-8-25-12-24)13-27-23(18)31/h3-5,7,9-11,25,28H,6,8,12-13H2,1-2H3,(H,27,31)(H,26,29,30)	SWTKULKSQOJRAV-UHFFFAOYSA-N	50360554	CHEMBL1933188	MAP kinase-activated protein kinase 2	Homo sapiens				 240					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360554&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400386	136964616		CHEMBL1933188				ZINC73240299	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709374	FC(F)(F)c1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H22F3N5O2/c25-24(26,27)16-4-1-3-15(9-16)21(33)32-19-10-14(5-8-29-19)18-11-17-20(31-18)23(13-30-22(17)34)6-2-7-28-12-23/h1,3-5,8-11,28,31H,2,6-7,12-13H2,(H,30,34)(H,29,32,33)	FEVPBNYNYKIJAR-UHFFFAOYSA-N	50360555	CHEMBL1933187	MAP kinase-activated protein kinase 2	Homo sapiens				 590					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360555&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	I85	3SHE	57395185	136964617		CHEMBL1933187				ZINC73240294	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709375	Fc1cc(F)cc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H21F2N5O2/c24-15-6-14(7-16(25)9-15)21(31)30-19-8-13(2-5-27-19)18-10-17-20(29-18)23(12-28-22(17)32)3-1-4-26-11-23/h2,5-10,26,29H,1,3-4,11-12H2,(H,28,32)(H,27,30,31)	DCOPJWXPAYWITJ-UHFFFAOYSA-N	50360556	CHEMBL1933186	MAP kinase-activated protein kinase 2	Homo sapiens				 590					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360556&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391727	136964618		CHEMBL1933186				ZINC73240285	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709376	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1ccccn1	InChI=1S/C22H22N6O2/c29-20-15-11-17(27-19(15)22(13-26-20)6-3-7-23-12-22)14-5-9-25-18(10-14)28-21(30)16-4-1-2-8-24-16/h1-2,4-5,8-11,23,27H,3,6-7,12-13H2,(H,26,29)(H,25,28,30)	BPABKQIJZOOSGR-UHFFFAOYSA-N	50360557	CHEMBL1933185	MAP kinase-activated protein kinase 2	Homo sapiens				 660					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360557&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398709	136964619		CHEMBL1933185				ZINC73240280	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709377	FC(F)(F)c1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H22F3N5O2/c25-24(26,27)16-4-2-14(3-5-16)21(33)32-19-10-15(6-9-29-19)18-11-17-20(31-18)23(13-30-22(17)34)7-1-8-28-12-23/h2-6,9-11,28,31H,1,7-8,12-13H2,(H,30,34)(H,29,32,33)	NMFTXZYZNCQGNR-UHFFFAOYSA-N	50360558	CHEMBL1933184	MAP kinase-activated protein kinase 2	Homo sapiens				 1200					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360558&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400385	136964620		CHEMBL1933184				ZINC82158179	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709378	FC(F)(F)Oc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C24H22F3N5O3/c25-24(26,27)35-16-4-1-3-15(9-16)21(33)32-19-10-14(5-8-29-19)18-11-17-20(31-18)23(13-30-22(17)34)6-2-7-28-12-23/h1,3-5,8-11,28,31H,2,6-7,12-13H2,(H,30,34)(H,29,32,33)	LRSZNMCVFHOKHV-UHFFFAOYSA-N	50360559	CHEMBL1933183	MAP kinase-activated protein kinase 2	Homo sapiens				 610					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360559&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400384	136964621		CHEMBL1933183				ZINC82157891	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709379	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-4-2-14(3-5-16)21(30)29-19-10-15(6-9-26-19)18-11-17-20(28-18)23(13-27-22(17)31)7-1-8-25-12-23/h2-6,9-11,25,28H,1,7-8,12-13H2,(H,27,31)(H,26,29,30)	UDOBRIMHNLEDHZ-UHFFFAOYSA-N	50360561	CHEMBL1933181	MAP kinase-activated protein kinase 2	Homo sapiens				 7400					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400383	136964623		CHEMBL1933181				ZINC73219230	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709380	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-4-2-14(3-5-16)21(30)29-19-10-15(6-9-26-19)18-11-17-20(28-18)23(13-27-22(17)31)7-1-8-25-12-23/h2-6,9-11,25,28H,1,7-8,12-13H2,(H,27,31)(H,26,29,30)	UDOBRIMHNLEDHZ-UHFFFAOYSA-N	50360561	CHEMBL1933181	MAP kinase-activated protein kinase 2	Homo sapiens				 7400					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400383	136964623		CHEMBL1933181				ZINC73219230	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709381	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-4-2-14(3-5-16)21(30)29-19-10-15(6-9-26-19)18-11-17-20(28-18)23(13-27-22(17)31)7-1-8-25-12-23/h2-6,9-11,25,28H,1,7-8,12-13H2,(H,27,31)(H,26,29,30)	UDOBRIMHNLEDHZ-UHFFFAOYSA-N	50360561	CHEMBL1933181	MAP kinase-activated protein kinase 2	Homo sapiens				 320					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400383	136964623		CHEMBL1933181				ZINC73219230	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709382	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1cccc2ccccc12	InChI=1S/C27H25N5O2/c33-25-21-14-22(31-24(21)27(16-30-25)10-4-11-28-15-27)18-9-12-29-23(13-18)32-26(34)20-8-3-6-17-5-1-2-7-19(17)20/h1-3,5-9,12-14,28,31H,4,10-11,15-16H2,(H,30,33)(H,29,32,34)	BQTRFPKZTXCUPV-UHFFFAOYSA-N	50360562	CHEMBL1933180	MAP kinase-activated protein kinase 2	Homo sapiens				 1100					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360562&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393464	136964624		CHEMBL1933180				ZINC73219225	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709383	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C27H25N5O2/c33-25(20-7-6-17-4-1-2-5-18(17)12-20)32-23-13-19(8-11-29-23)22-14-21-24(31-22)27(16-30-26(21)34)9-3-10-28-15-27/h1-2,4-8,11-14,28,31H,3,9-10,15-16H2,(H,30,34)(H,29,32,33)	YUIHVDXPZJATDG-UHFFFAOYSA-N	50360563	CHEMBL1933179	MAP kinase-activated protein kinase 2	Homo sapiens				 530					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360563&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403940	136964625		CHEMBL1933179				ZINC73240489	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709384	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C27H25N5O2/c33-25(20-7-6-17-4-1-2-5-18(17)12-20)32-23-13-19(8-11-29-23)22-14-21-24(31-22)27(16-30-26(21)34)9-3-10-28-15-27/h1-2,4-8,11-14,28,31H,3,9-10,15-16H2,(H,30,34)(H,29,32,33)	YUIHVDXPZJATDG-UHFFFAOYSA-N	50360563	CHEMBL1933179	MAP kinase-activated protein kinase 2	Homo sapiens				 530					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360563&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403940	136964625		CHEMBL1933179				ZINC73240489	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709385	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C25H27N5O2/c1-15-4-5-18(10-16(15)2)23(31)30-21-11-17(6-9-27-21)20-12-19-22(29-20)25(14-28-24(19)32)7-3-8-26-13-25/h4-6,9-12,26,29H,3,7-8,13-14H2,1-2H3,(H,28,32)(H,27,30,31)	BAYAFUAQZUNFQN-UHFFFAOYSA-N	50360564	CHEMBL1933178	MAP kinase-activated protein kinase 2	Homo sapiens				 5300					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360564&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393463	136964626		CHEMBL1933178				ZINC73223715	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709386	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C25H27N5O2/c1-15-4-5-18(10-16(15)2)23(31)30-21-11-17(6-9-27-21)20-12-19-22(29-20)25(14-28-24(19)32)7-3-8-26-13-25/h4-6,9-12,26,29H,3,7-8,13-14H2,1-2H3,(H,28,32)(H,27,30,31)	BAYAFUAQZUNFQN-UHFFFAOYSA-N	50360564	CHEMBL1933178	MAP kinase-activated protein kinase 2	Homo sapiens				 5300					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360564&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393463	136964626		CHEMBL1933178				ZINC73223715	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709387	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1ccncc1	InChI=1S/C22H22N6O2/c29-20(14-1-6-23-7-2-14)28-18-11-15(3-8-25-18)17-12-16-19(27-17)22(13-26-21(16)30)4-9-24-10-5-22/h1-3,6-8,11-12,24,27H,4-5,9-10,13H2,(H,26,30)(H,25,28,29)	USWNIDNQZMFUOA-UHFFFAOYSA-N	50360565	CHEMBL1933177	MAP kinase-activated protein kinase 2	Homo sapiens				>10000					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360565&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393462	136964627		CHEMBL1933177				ZINC73223712	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709388	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1ccccn1	InChI=1S/C22H22N6O2/c29-20-15-12-17(27-19(15)22(13-26-20)5-9-23-10-6-22)14-4-8-25-18(11-14)28-21(30)16-3-1-2-7-24-16/h1-4,7-8,11-12,23,27H,5-6,9-10,13H2,(H,26,29)(H,25,28,30)	WKBRFCZMWWOFLS-UHFFFAOYSA-N	50360566	CHEMBL1933176	MAP kinase-activated protein kinase 2	Homo sapiens				 550					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360566&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393461	136964628		CHEMBL1933176				ZINC73223833	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709389	FC(F)(F)c1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C24H22F3N5O2/c25-24(26,27)16-3-1-14(2-4-16)21(33)32-19-11-15(5-8-29-19)18-12-17-20(31-18)23(13-30-22(17)34)6-9-28-10-7-23/h1-5,8,11-12,28,31H,6-7,9-10,13H2,(H,30,34)(H,29,32,33)	ADSKPKMUCXKPLL-UHFFFAOYSA-N	50360567	CHEMBL1933175	MAP kinase-activated protein kinase 2	Homo sapiens				 1300					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360567&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57402272	136964629		CHEMBL1933175				ZINC73223831	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709390	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2cccc(OC(F)(F)F)c2)c1	InChI=1S/C25H24F3N5O3/c1-33-9-6-24(7-10-33)14-30-23(35)18-13-19(31-21(18)24)15-5-8-29-20(12-15)32-22(34)16-3-2-4-17(11-16)36-25(26,27)28/h2-5,8,11-13,31H,6-7,9-10,14H2,1H3,(H,30,35)(H,29,32,34)	LIGULLZQUPLXHT-UHFFFAOYSA-N	50360568	CHEMBL1933174	MAP kinase-activated protein kinase 2	Homo sapiens				 830					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360568&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835160	136964630		CHEMBL1933174				ZINC73223830	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709391	FC(F)(F)Oc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C24H22F3N5O3/c25-24(26,27)35-16-3-1-2-15(10-16)21(33)32-19-11-14(4-7-29-19)18-12-17-20(31-18)23(13-30-22(17)34)5-8-28-9-6-23/h1-4,7,10-12,28,31H,5-6,8-9,13H2,(H,30,34)(H,29,32,33)	IYTUIXSZTJRKJK-UHFFFAOYSA-N	50360569	CHEMBL1933173	MAP kinase-activated protein kinase 2	Homo sapiens				 130					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360569&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835159	136964631		CHEMBL1933173				ZINC73223827	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709392	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2cccc(F)c2)c1	InChI=1S/C24H24FN5O2/c1-30-9-6-24(7-10-30)14-27-23(32)18-13-19(28-21(18)24)15-5-8-26-20(12-15)29-22(31)16-3-2-4-17(25)11-16/h2-5,8,11-13,28H,6-7,9-10,14H2,1H3,(H,27,32)(H,26,29,31)	DODIBPZRZYINLL-UHFFFAOYSA-N	50360570	CHEMBL1933172	MAP kinase-activated protein kinase 2	Homo sapiens				 640					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360570&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835142	136964632		CHEMBL1933172				ZINC73224963	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709393	Fc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-3-1-2-15(10-16)21(30)29-19-11-14(4-7-26-19)18-12-17-20(28-18)23(13-27-22(17)31)5-8-25-9-6-23/h1-4,7,10-12,25,28H,5-6,8-9,13H2,(H,27,31)(H,26,29,30)	KNKFHJYKSHDVBU-UHFFFAOYSA-N	50360571	CHEMBL1933171	MAP kinase-activated protein kinase 2	Homo sapiens				 680					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360571&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835141	136964633		CHEMBL1933171				ZINC73224714	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709394	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2ccc3ccccc3c2)c1	InChI=1S/C28H27N5O2/c1-33-12-9-28(10-13-33)17-30-27(35)22-16-23(31-25(22)28)20-8-11-29-24(15-20)32-26(34)21-7-6-18-4-2-3-5-19(18)14-21/h2-8,11,14-16,31H,9-10,12-13,17H2,1H3,(H,30,35)(H,29,32,34)	DOLWWDXSZGJMTH-UHFFFAOYSA-N	50360572	CHEMBL1933170	MAP kinase-activated protein kinase 2	Homo sapiens				 730					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360572&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835140	136964634		CHEMBL1933170				ZINC82157983	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709395	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2ccc(C)c(C)c2)c1	InChI=1S/C26H29N5O2/c1-16-4-5-19(12-17(16)2)24(32)30-22-13-18(6-9-27-22)21-14-20-23(29-21)26(15-28-25(20)33)7-10-31(3)11-8-26/h4-6,9,12-14,29H,7-8,10-11,15H2,1-3H3,(H,28,33)(H,27,30,32)	OAVAWUCQTZYDRR-UHFFFAOYSA-N	50360573	CHEMBL1933169	MAP kinase-activated protein kinase 2	Homo sapiens				 920					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360573&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835138	136964635		CHEMBL1933169				ZINC82157981	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709396	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-3-1-14(2-4-16)21(30)29-19-11-15(5-8-26-19)18-12-17-20(28-18)23(13-27-22(17)31)6-9-25-10-7-23/h1-5,8,11-12,25,28H,6-7,9-10,13H2,(H,27,31)(H,26,29,30)	GONILSJCINFJBM-UHFFFAOYSA-N	50360574	CHEMBL1933168	MAP kinase-activated protein kinase 2	Homo sapiens				 3700					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360574&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393540	136964636		CHEMBL1933168				ZINC82157980	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709397	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1cccc2ccccc12	InChI=1S/C27H25N5O2/c33-25-21-15-22(31-24(21)27(16-30-25)9-12-28-13-10-27)18-8-11-29-23(14-18)32-26(34)20-7-3-5-17-4-1-2-6-19(17)20/h1-8,11,14-15,28,31H,9-10,12-13,16H2,(H,30,33)(H,29,32,34)	KQSZPJVZDFCDBQ-UHFFFAOYSA-N	50360575	CHEMBL1933166	MAP kinase-activated protein kinase 2	Homo sapiens				 520					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360575&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57404001	136964637		CHEMBL1933166				ZINC73387147	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709398	Cc1ccc(cc1C)C(=O)Nc1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C24H26N6O2/c1-14-3-4-16(11-15(14)2)21(31)30-23-26-8-5-18(29-23)19-12-17-20(28-19)24(13-27-22(17)32)6-9-25-10-7-24/h3-5,8,11-12,25,28H,6-7,9-10,13H2,1-2H3,(H,27,32)(H,26,29,30,31)	RQGMNVCQBKKPKI-UHFFFAOYSA-N	50360576	CHEMBL1933161	MAP kinase-activated protein kinase 2	Homo sapiens				 3.1					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360576	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360576&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395255	136964638		CHEMBL1933161				ZINC82157943	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709399	O=C1NCC2(CCNCC2)c2[nH]c(cc12)-c1ccnc(n1)-c1ccc2OCOc2c1	InChI=1S/C22H21N5O3/c28-21-14-10-16(26-19(14)22(11-25-21)4-7-23-8-5-22)15-3-6-24-20(27-15)13-1-2-17-18(9-13)30-12-29-17/h1-3,6,9-10,23,26H,4-5,7-8,11-12H2,(H,25,28)	QSDGMDKMSSYMKU-UHFFFAOYSA-N	50344696	2'-(2-(benzo[d][1,3]dioxol-5-yl)pyrimidin-4-yl)-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::2'-[2-(1,3-benzodioxol-5-yl)pyrimidin-4-yl]-5',6'-dihydrospiro[piperidine-4,7'-pyrrolo[3,2-c]pyridin]-4'(1'H)-one::CHEMBL1738702	MAP kinase-activated protein kinase 2	Homo sapiens				 4.3					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50344696	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50344696&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	05B	3R1N,3R2B	53326866	131347632		CHEMBL1738702				ZINC66156777	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709400	Fc1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-3-1-14(2-4-16)21(30)29-19-11-15(5-8-26-19)18-12-17-20(28-18)23(13-27-22(17)31)6-9-25-10-7-23/h1-5,8,11-12,25,28H,6-7,9-10,13H2,(H,27,31)(H,26,29,30)	GONILSJCINFJBM-UHFFFAOYSA-N	50360574	CHEMBL1933168	MAP kinase-activated protein kinase 2	Homo sapiens				 1.6					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360574&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393540	136964636		CHEMBL1933168				ZINC82157980	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709401	Fc1ccc(cc1)C(=O)Nc1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C22H21FN6O2/c23-14-3-1-13(2-4-14)19(30)29-21-25-8-5-16(28-21)17-11-15-18(27-17)22(12-26-20(15)31)6-9-24-10-7-22/h1-5,8,11,24,27H,6-7,9-10,12H2,(H,26,31)(H,25,28,29,30)	USSJYZZQLCSXBS-UHFFFAOYSA-N	50360577	CHEMBL1933167	MAP kinase-activated protein kinase 2	Homo sapiens				 15					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360577	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360577&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57402271	136964639		CHEMBL1933167				ZINC82157979	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709402	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1cccc2ccccc12	InChI=1S/C27H25N5O2/c33-25-21-15-22(31-24(21)27(16-30-25)9-12-28-13-10-27)18-8-11-29-23(14-18)32-26(34)20-7-3-5-17-4-1-2-6-19(17)20/h1-8,11,14-15,28,31H,9-10,12-13,16H2,(H,30,33)(H,29,32,34)	KQSZPJVZDFCDBQ-UHFFFAOYSA-N	50360575	CHEMBL1933166	MAP kinase-activated protein kinase 2	Homo sapiens				 0.96					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360575&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57404001	136964637		CHEMBL1933166				ZINC73387147	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709403	O=C(Nc1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1cccc2ccccc12	InChI=1S/C26H24N6O2/c33-23-19-14-21(30-22(19)26(15-29-23)9-12-27-13-10-26)20-8-11-28-25(31-20)32-24(34)18-7-3-5-16-4-1-2-6-17(16)18/h1-8,11,14,27,30H,9-10,12-13,15H2,(H,29,33)(H,28,31,32,34)	LOPSXLUFHHAEOK-UHFFFAOYSA-N	50360578	CHEMBL1933165	MAP kinase-activated protein kinase 2	Homo sapiens				 14					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360578	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360578&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57402270	136964640		CHEMBL1933165				ZINC73219115	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709404	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C27H25N5O2/c33-25(20-6-5-17-3-1-2-4-18(17)13-20)32-23-14-19(7-10-29-23)22-15-21-24(31-22)27(16-30-26(21)34)8-11-28-12-9-27/h1-7,10,13-15,28,31H,8-9,11-12,16H2,(H,30,34)(H,29,32,33)	DWRIDLORHRQUGO-UHFFFAOYSA-N	50360547	CHEMBL1933164	MAP kinase-activated protein kinase 2	Homo sapiens				 0.72					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360547&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835139	136964609		CHEMBL1933164				ZINC73223479	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709405	O=C(Nc1nccc(n1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C26H24N6O2/c33-23(18-6-5-16-3-1-2-4-17(16)13-18)32-25-28-10-7-20(31-25)21-14-19-22(30-21)26(15-29-24(19)34)8-11-27-12-9-26/h1-7,10,13-14,27,30H,8-9,11-12,15H2,(H,29,34)(H,28,31,32,33)	VTSGFJSEVNWKKI-UHFFFAOYSA-N	50360579	CHEMBL1933163	MAP kinase-activated protein kinase 2	Homo sapiens				 5.1					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360579&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400468	136964641		CHEMBL1933163				ZINC73223477	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709406	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C25H27N5O2/c1-15-3-4-18(11-16(15)2)23(31)30-21-12-17(5-8-27-21)20-13-19-22(29-20)25(14-28-24(19)32)6-9-26-10-7-25/h3-5,8,11-13,26,29H,6-7,9-10,14H2,1-2H3,(H,28,32)(H,27,30,31)	JLSAYGNBEXSZKV-UHFFFAOYSA-N	50360548	CHEMBL1933162	MAP kinase-activated protein kinase 2	Homo sapiens				 1					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360548&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835137	136964610		CHEMBL1933162				ZINC73223475	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709407	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C27H25N5O2/c33-25(20-7-6-17-4-1-2-5-18(17)12-20)32-23-13-19(8-11-29-23)22-14-21-24(31-22)27(16-30-26(21)34)9-3-10-28-15-27/h1-2,4-8,11-14,28,31H,3,9-10,15-16H2,(H,30,34)(H,29,32,33)	YUIHVDXPZJATDG-UHFFFAOYSA-N	50360563	CHEMBL1933179	MAP kinase-activated protein kinase 2	Homo sapiens				 129					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360563&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403940	136964625		CHEMBL1933179				ZINC73240489	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709408	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O)c1ccc2ccccc2c1	InChI=1S/C27H25N5O2/c33-25(20-7-6-17-4-1-2-5-18(17)12-20)32-23-13-19(8-11-29-23)22-14-21-24(31-22)27(16-30-26(21)34)9-3-10-28-15-27/h1-2,4-8,11-14,28,31H,3,9-10,15-16H2,(H,30,34)(H,29,32,33)	YUIHVDXPZJATDG-UHFFFAOYSA-N	50360563	CHEMBL1933179	MAP kinase-activated protein kinase 2	Homo sapiens				 2.50					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360563&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403940	136964625		CHEMBL1933179				ZINC73240489	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709409	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C25H27N5O2/c1-15-4-5-18(10-16(15)2)23(31)30-21-11-17(6-9-27-21)20-12-19-22(29-20)25(14-28-24(19)32)7-3-8-26-13-25/h4-6,9-12,26,29H,3,7-8,13-14H2,1-2H3,(H,28,32)(H,27,30,31)	BAYAFUAQZUNFQN-UHFFFAOYSA-N	50360564	CHEMBL1933178	MAP kinase-activated protein kinase 2	Homo sapiens				 32					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360564&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393463	136964626		CHEMBL1933178				ZINC73223715	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709410	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C25H27N5O2/c1-15-4-5-18(10-16(15)2)23(31)30-21-11-17(6-9-27-21)20-12-19-22(29-20)25(14-28-24(19)32)7-3-8-26-13-25/h4-6,9-12,26,29H,3,7-8,13-14H2,1-2H3,(H,28,32)(H,27,30,31)	BAYAFUAQZUNFQN-UHFFFAOYSA-N	50360564	CHEMBL1933178	MAP kinase-activated protein kinase 2	Homo sapiens				 32.0					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360564&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393463	136964626		CHEMBL1933178				ZINC73223715	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709411	Cc1ccc(cc1C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O	InChI=1S/C25H27N5O2/c1-15-4-5-18(10-16(15)2)23(31)30-21-11-17(6-9-27-21)20-12-19-22(29-20)25(14-28-24(19)32)7-3-8-26-13-25/h4-6,9-12,26,29H,3,7-8,13-14H2,1-2H3,(H,28,32)(H,27,30,31)	BAYAFUAQZUNFQN-UHFFFAOYSA-N	50360564	CHEMBL1933178	MAP kinase-activated protein kinase 2	Homo sapiens				 5.50					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360564&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393463	136964626		CHEMBL1933178				ZINC73223715	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709412	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1ccncc1	InChI=1S/C22H22N6O2/c29-20(14-1-6-23-7-2-14)28-18-11-15(3-8-25-18)17-12-16-19(27-17)22(13-26-21(16)30)4-9-24-10-5-22/h1-3,6-8,11-12,24,27H,4-5,9-10,13H2,(H,26,30)(H,25,28,29)	USWNIDNQZMFUOA-UHFFFAOYSA-N	50360565	CHEMBL1933177	MAP kinase-activated protein kinase 2	Homo sapiens				 2.6					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360565&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393462	136964627		CHEMBL1933177				ZINC73223712	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709413	O=C(Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O)c1ccccn1	InChI=1S/C22H22N6O2/c29-20-15-12-17(27-19(15)22(13-26-20)5-9-23-10-6-22)14-4-8-25-18(11-14)28-21(30)16-3-1-2-7-24-16/h1-4,7-8,11-12,23,27H,5-6,9-10,13H2,(H,26,29)(H,25,28,30)	WKBRFCZMWWOFLS-UHFFFAOYSA-N	50360566	CHEMBL1933176	MAP kinase-activated protein kinase 2	Homo sapiens				 1.4					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360566&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393461	136964628		CHEMBL1933176				ZINC73223833	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709414	FC(F)(F)c1ccc(cc1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C24H22F3N5O2/c25-24(26,27)16-3-1-14(2-4-16)21(33)32-19-11-15(5-8-29-19)18-12-17-20(31-18)23(13-30-22(17)34)6-9-28-10-7-23/h1-5,8,11-12,28,31H,6-7,9-10,13H2,(H,30,34)(H,29,32,33)	ADSKPKMUCXKPLL-UHFFFAOYSA-N	50360567	CHEMBL1933175	MAP kinase-activated protein kinase 2	Homo sapiens				 1.6					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360567&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57402272	136964629		CHEMBL1933175				ZINC73223831	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709415	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2cccc(OC(F)(F)F)c2)c1	InChI=1S/C25H24F3N5O3/c1-33-9-6-24(7-10-33)14-30-23(35)18-13-19(31-21(18)24)15-5-8-29-20(12-15)32-22(34)16-3-2-4-17(11-16)36-25(26,27)28/h2-5,8,11-13,31H,6-7,9-10,14H2,1H3,(H,30,35)(H,29,32,34)	LIGULLZQUPLXHT-UHFFFAOYSA-N	50360568	CHEMBL1933174	MAP kinase-activated protein kinase 2	Homo sapiens				 2.7					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360568&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835160	136964630		CHEMBL1933174				ZINC73223830	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709416	FC(F)(F)Oc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C24H22F3N5O3/c25-24(26,27)35-16-3-1-2-15(10-16)21(33)32-19-11-14(4-7-29-19)18-12-17-20(31-18)23(13-30-22(17)34)5-8-28-9-6-23/h1-4,7,10-12,28,31H,5-6,8-9,13H2,(H,30,34)(H,29,32,33)	IYTUIXSZTJRKJK-UHFFFAOYSA-N	50360569	CHEMBL1933173	MAP kinase-activated protein kinase 2	Homo sapiens				 1.5					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360569&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835159	136964631		CHEMBL1933173				ZINC73223827	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709417	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2cccc(F)c2)c1	InChI=1S/C24H24FN5O2/c1-30-9-6-24(7-10-30)14-27-23(32)18-13-19(28-21(18)24)15-5-8-26-20(12-15)29-22(31)16-3-2-4-17(25)11-16/h2-5,8,11-13,28H,6-7,9-10,14H2,1H3,(H,27,32)(H,26,29,31)	DODIBPZRZYINLL-UHFFFAOYSA-N	50360570	CHEMBL1933172	MAP kinase-activated protein kinase 2	Homo sapiens				 2.5					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360570&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835142	136964632		CHEMBL1933172				ZINC73224963	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709418	Fc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCNCC1)CNC2=O	InChI=1S/C23H22FN5O2/c24-16-3-1-2-15(10-16)21(30)29-19-11-14(4-7-26-19)18-12-17-20(28-18)23(13-27-22(17)31)5-8-25-9-6-23/h1-4,7,10-12,25,28H,5-6,8-9,13H2,(H,27,31)(H,26,29,30)	KNKFHJYKSHDVBU-UHFFFAOYSA-N	50360571	CHEMBL1933171	MAP kinase-activated protein kinase 2	Homo sapiens				 1.1					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360571&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835141	136964633		CHEMBL1933171				ZINC73224714	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709419	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2ccc3ccccc3c2)c1	InChI=1S/C28H27N5O2/c1-33-12-9-28(10-13-33)17-30-27(35)22-16-23(31-25(22)28)20-8-11-29-24(15-20)32-26(34)21-7-6-18-4-2-3-5-19(18)14-21/h2-8,11,14-16,31H,9-10,12-13,17H2,1H3,(H,30,35)(H,29,32,34)	DOLWWDXSZGJMTH-UHFFFAOYSA-N	50360572	CHEMBL1933170	MAP kinase-activated protein kinase 2	Homo sapiens				 2.6					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360572&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835140	136964634		CHEMBL1933170				ZINC82157983	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709420	CN1CCC2(CC1)CNC(=O)c1cc([nH]c21)-c1ccnc(NC(=O)c2ccc(C)c(C)c2)c1	InChI=1S/C26H29N5O2/c1-16-4-5-19(12-17(16)2)24(32)30-22-13-18(6-9-27-22)21-14-20-23(29-21)26(15-28-25(20)33)7-10-31(3)11-8-26/h4-6,9,12-14,29H,7-8,10-11,15H2,1-3H3,(H,28,33)(H,27,30,32)	OAVAWUCQTZYDRR-UHFFFAOYSA-N	50360573	CHEMBL1933169	MAP kinase-activated protein kinase 2	Homo sapiens				 2.3					ChEMBL	10.1016/j.bmcl.2011.10.071	10.7270/Q2RN389G	22119462			Oubrie, A; Kaptein, A; de Zwart, E; Hoogenboom, N; Goorden, R; van de Kar, B; van Hoek, M; de Kimpe, V; van der Heijden, R; Borsboom, J; Kazemier, B; de Roos, J; Scheffers, M; Lommerse, J; Schultz-Fademrecht, C; Barf, T	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360573&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835138	136964635		CHEMBL1933169				ZINC82157981	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50695703	O=C(N1CCNCC1)c1ccc(\C=C\c2n[nH]c3ccccc23)cc1	InChI=1S/C20H20N4O/c25-20(24-13-11-21-12-14-24)16-8-5-15(6-9-16)7-10-19-17-3-1-2-4-18(17)22-23-19/h1-10,21H,11-14H2,(H,22,23)/b10-7+	YYLKKYCXAOBSRM-JXMROGBWSA-N	50355496	CHEMBL1908397	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50355496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50355496&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11427553	136959520		CHEMBL1908397				ZINC43201999	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709498	Fc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(C2)C2CCCNC2)c2ccccc12	InChI=1S/C25H27FN4O/c26-18-7-8-21-17(12-18)13-22(28-21)24(31)30-16-25(20-5-1-2-6-23(20)30)9-11-29(15-25)19-4-3-10-27-14-19/h1-2,5-8,12-13,19,27-28H,3-4,9-11,14-16H2/t19?,25-/m1/s1	ABNVVKAVWJYHCL-OPEAARRCSA-N	50360605	CHEMBL1933538	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2011.11.036	10.7270/Q2CF9QJS	22119469			Powell, NA; Kohrt, JT; Filipski, KJ; Kaufman, M; Sheehan, D; Edmunds, JE; Delaney, A; Wang, Y; Bourbonais, F; Lee, DY; Schwende, F; Sun, F; McConnell, P; Catana, C; Chen, H; Ohren, J; Perrin, LA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360605	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360605&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57396882	136964667		CHEMBL1933538				ZINC73224360	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50710588	CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2nccc(n2)-c2cc(cn2C)C(N)=O)c1	InChI=1S/C22H24F3N7O2/c1-30-7-9-32(10-8-30)15-3-4-19(34-22(23,24)25)17(12-15)29-21-27-6-5-16(28-21)18-11-14(20(26)33)13-31(18)2/h3-6,11-13H,7-10H2,1-2H3,(H2,26,33)(H,27,28,29)	HGBZKLOZYQAERY-UHFFFAOYSA-N	50361089	CHEMBL1933576	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2011.11.065	10.7270/Q2W959NX	22154349			Caruso, M; Valsasina, B; Ballinari, D; Bertrand, J; Brasca, MG; Caldarelli, M; Cappella, P; Fiorentini, F; Gianellini, LM; Scolaro, A; Beria, I	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361089	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361089&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	939	4A4L	54759168	136965151		CHEMBL1933576				ZINC73219127	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50710589	CN1CCN(CC1)c1ccc(OC(F)(F)F)c(Nc2nccc(n2)-c2cc3c(CCNC3=O)n2C)c1	InChI=1S/C24H26F3N7O2/c1-32-9-11-34(12-10-32)15-3-4-21(36-24(25,26)27)18(13-15)31-23-29-7-5-17(30-23)20-14-16-19(33(20)2)6-8-28-22(16)35/h3-5,7,13-14H,6,8-12H2,1-2H3,(H,28,35)(H,29,30,31)	CYXABCVHENZAID-UHFFFAOYSA-N	50361088	CHEMBL1933582	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmcl.2011.11.065	10.7270/Q2W959NX	22154349			Caruso, M; Valsasina, B; Ballinari, D; Bertrand, J; Brasca, MG; Caldarelli, M; Cappella, P; Fiorentini, F; Gianellini, LM; Scolaro, A; Beria, I	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50361088	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50361088&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	664	4A4O	25210579	136965150		CHEMBL1933582				ZINC43205093	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709516	Fc1ccc2cc([nH]c2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNC2)c2ccccc12	InChI=1S/C24H25FN4O/c25-17-6-5-16-11-21(27-20(16)12-17)23(30)29-15-24(19-3-1-2-4-22(19)29)8-10-28(14-24)18-7-9-26-13-18/h1-6,11-12,18,26-27H,7-10,13-15H2/t18?,24-/m1/s1	FTHSNABZISUYPK-VCUSLETLSA-N	50360611	CHEMBL1933550	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2011.11.036	10.7270/Q2CF9QJS	22119469			Powell, NA; Kohrt, JT; Filipski, KJ; Kaufman, M; Sheehan, D; Edmunds, JE; Delaney, A; Wang, Y; Bourbonais, F; Lee, DY; Schwende, F; Sun, F; McConnell, P; Catana, C; Chen, H; Ohren, J; Perrin, LA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360611	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360611&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56835089	136964673		CHEMBL1933550				ZINC73224774	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709546	C[C@@H]1CCC(CN1)N1CC[C@@]2(C1)CN(C(=O)c1cc3ccccc3[nH]1)c1ccccc21	InChI=1S/C26H30N4O/c1-18-10-11-20(15-27-18)29-13-12-26(16-29)17-30(24-9-5-3-7-21(24)26)25(31)23-14-19-6-2-4-8-22(19)28-23/h2-9,14,18,20,27-28H,10-13,15-17H2,1H3/t18-,20?,26-/m1/s1	XXRJWFOMOOANJW-MKBNCEHSSA-N	50360609	CHEMBL1933551	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2011.11.036	10.7270/Q2CF9QJS	22119469			Powell, NA; Kohrt, JT; Filipski, KJ; Kaufman, M; Sheehan, D; Edmunds, JE; Delaney, A; Wang, Y; Bourbonais, F; Lee, DY; Schwende, F; Sun, F; McConnell, P; Catana, C; Chen, H; Ohren, J; Perrin, LA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360609	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360609&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395116	136964671		CHEMBL1933551				ZINC73219251	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50709575	C[C@@H]1CCC(CN1)N1CC[C@@]2(C1)CN(C(=O)c1cc3ccc(F)cc3[nH]1)c1ccccc21	InChI=1S/C26H29FN4O/c1-17-6-9-20(14-28-17)30-11-10-26(15-30)16-31(24-5-3-2-4-21(24)26)25(32)23-12-18-7-8-19(27)13-22(18)29-23/h2-5,7-8,12-13,17,20,28-29H,6,9-11,14-16H2,1H3/t17-,20?,26-/m1/s1	MYPHZBOANNRFAS-JTPVZTEWSA-N	50360610	CHEMBL1933552	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2011.11.036	10.7270/Q2CF9QJS	22119469			Powell, NA; Kohrt, JT; Filipski, KJ; Kaufman, M; Sheehan, D; Edmunds, JE; Delaney, A; Wang, Y; Bourbonais, F; Lee, DY; Schwende, F; Sun, F; McConnell, P; Catana, C; Chen, H; Ohren, J; Perrin, LA	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50360610	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50360610&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395117	136964672		CHEMBL1933552				ZINC73219256	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50697323	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50694748	CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c1F	InChI=1S/C17H14ClF2N3O3S/c1-2-5-27(25,26)23-13-4-3-12(19)14(15(13)20)16(24)11-8-22-17-10(11)6-9(18)7-21-17/h3-4,6-8,23H,2,5H2,1H3,(H,21,22)	YZDJQTHVDDOVHR-UHFFFAOYSA-N	25617	N-[3-({5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl}carbonyl)-2,4-difluorophenyl]propane-1-sulfonamide::PLX4720	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25617	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25617&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	324	3C4C,4WO5	24180719	56412907			DB06999	5703		ZINC39059267	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50694791	Cc1cnc2c(NCCN)nc3ccc(C)cc3n12	InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)	PSPFQEBFYXJZEV-UHFFFAOYSA-N	25919	BMS-345541::BMS345541::CHEMBL471496::N-(2-aminoethyl)-3,12-dimethyl-2,5,8-triazatricyclo[7.4.0.0^{2,6}]trideca-1(13),3,5,7,9,11-hexaen-7-amine	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25919&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9813758	56413207		CHEMBL471496		5669		ZINC13285379	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50697563	COc1cc(Nc2c(cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)C#N)c(Cl)cc1Cl	InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)	UBPYILGKFZZVDX-UHFFFAOYSA-N	4552	4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile::4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile::BOSUTINIB::CHEMBL288441::SKI-606	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4552&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	DB8	6OP9,5AJQ,4MXO,4MXY,4MXX,4MXZ,3SOA,5VC3,6FDY,5I9X,3UE4,4QMN,5VCY	5328940	8034215	39112	CHEMBL288441	DB06616	5710		ZINC22448983	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50706407	CN(C)CCN1CCN(CCC1=O)C(=O)c1cc(sc1NC(=O)Nc1cccc(Cl)c1Cl)C(C)(C)C	InChI=1S/C25H33Cl2N5O3S/c1-25(2,3)19-15-16(22(36-19)29-24(35)28-18-8-6-7-17(26)21(18)27)23(34)32-10-9-20(33)31(13-14-32)12-11-30(4)5/h6-8,15H,9-14H2,1-5H3,(H2,28,29,35)	SIUIQMQVKUUQQF-UHFFFAOYSA-N	50359359	CHEMBL1929238	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2011.09.078	10.7270/Q2NC61NH	22014550			Moffett, K; Konteatis, Z; Nguyen, D; Shetty, R; Ludington, J; Fujimoto, T; Lee, KJ; Chai, X; Namboodiri, H; Karpusas, M; Dorsey, B; Guarnieri, F; Bukhtiyarova, M; Springman, E; Michelotti, E	Ansaris	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50359359	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50359359&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	P7C	3P7C	53384644	136963383		CHEMBL1929238				ZINC72318122	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50706408	Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C	InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	MVCOAUNKQVWQHZ-UHFFFAOYSA-N	13533	1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(4-methylphenyl)-3-pyrazolyl]-3-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea::1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea::3-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-1-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB 796::BIRB-796::BIRB-796, 3::CHEMBL103667::D3RKN_73::Doramapimod::US11407771, Compound 43::US8933228, BIRB 796::US9187470, 43 (BIRB-796)::US9242960, BIRB 796::US9260410, BIRB796::cid_156422::diaryl urea compound 10	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2011.09.078	10.7270/Q2NC61NH	22014550			Moffett, K; Konteatis, Z; Nguyen, D; Shetty, R; Ludington, J; Fujimoto, T; Lee, KJ; Chai, X; Namboodiri, H; Karpusas, M; Dorsey, B; Guarnieri, F; Bukhtiyarova, M; Springman, E; Michelotti, E	Ansaris	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13533&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B96	4JVG,1KV2,6GTT,5N66,4TWN,3NPC,3FZS	156422	46513934		CHEMBL103667	DB03044	5668		ZINC24044436	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50693581	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50694963	COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1	InChI=1S/C25H27FN4O3/c1-16-12-17-19(29-16)6-7-21(24(17)26)33-25-18-13-22(31-2)23(14-20(18)27-15-28-25)32-11-5-10-30-8-3-4-9-30/h6-7,12-15,29H,3-5,8-11H2,1-2H3	XXJWYDDUDKYVKI-UHFFFAOYSA-N	50331096	4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline::CHEMBL491473::Cediranib::US10464902, Cediranib::ZD-2171	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50331096	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50331096&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9933475	123110211		CHEMBL491473	DB04849	5664		ZINC03948085	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50693671	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50693694	Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F	InChI=1S/C28H22F3N7O/c1-17-5-6-19(10-25(17)37-27-33-9-7-24(36-27)20-4-3-8-32-14-20)26(39)35-22-11-21(28(29,30)31)12-23(13-22)38-15-18(2)34-16-38/h3-16H,1-2H3,(H,35,39)(H,33,36,37)	HHZIURLSWUIHRB-UHFFFAOYSA-N	50237710	4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide::AMN 107::AMN107::CHEMBL255863::NILOTINIB::US11649218, Example Nilotinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt.1990	10.7270/Q25D8S70	22037378			Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50237710	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50237710&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	NIL	5MO4,3CS9,3GP0	644241	104056419	52172	CHEMBL255863	DB04868	5697		ZINC06716957	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50715268	Cn1c2c(C(C#N)C3(CCNCC3)NC2=O)c2ccc(Cl)c(Cl)c12	InChI=1S/C17H16Cl2N4O/c1-23-14-9(2-3-11(18)13(14)19)12-10(8-20)17(4-6-21-7-5-17)22-16(24)15(12)23/h2-3,10,21H,4-7H2,1H3,(H,22,24)	OWAWOKKHZNRHGV-UHFFFAOYSA-N	50363167	CHEMBL1945559	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm201286z	10.7270/Q20G3KK7	22136433			Huber, K; Brault, L; Fedorov, O; Gasser, C; Filippakopoulos, P; Bullock, AN; Fabbro, D; Trappe, J; Schwaller, J; Knapp, S; Bracher, F	Ludwig-Maximilians University of Munich	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50363167	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50363167&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	KHC	6YTG,6Z2V,6YU1	54613583	136967229		CHEMBL1945559				ZINC73197039	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50720092	COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1	InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24)	MYQAUKPBNJWPIE-UHFFFAOYSA-N	32362	5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine::GW-2580::[2-amino-5-(3-methoxy-4-p-anisyloxy-benzyl)pyrimidin-4-yl]amine::cid_11617559	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1073/pnas.0502000102	10.7270/Q2PC32TB	16249345			Conway, JG; McDonald, B; Parham, J; Keith, B; Rusnak, DW; Shaw, E; Jansen, M; Lin, P; Payne, A; Crosby, RM; Johnson, JH; Frick, L; Lin, MH; Depee, S; Tadepalli, S; Votta, B; James, I; Fuller, K; Chambers, TJ; Kull, FC; Chamberlain, SD; Hutchins, JT	GlaxoSmithKline	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32362&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MUJ	4AT5	11617559	252615797				5685		ZINC13985942	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713047	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713048	O=C(N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C28H25N5O2/c29-19-21-4-6-22(7-5-21)26-12-13-27(35-26)28(34)33(20-23-3-1-2-14-31-23)25-10-8-24(9-11-25)32-17-15-30-16-18-32/h1-14,30H,15-18,20H2	OTHADZFQWXBMFV-UHFFFAOYSA-N	50362107	CHEMBL1940509	MAP kinase-activated protein kinase 2	Homo sapiens		 115							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362107	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362107&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393087	136966169		CHEMBL1940509				ZINC73219529	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713049	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)C1CCC(CC1)N1CCNCC1	InChI=1S/C27H31ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-7,12-14,23-24,29H,8-11,15-19H2	JPTHFWWSVYABJW-UHFFFAOYSA-N	50362108	CHEMBL1940510	MAP kinase-activated protein kinase 2	Homo sapiens		 4743							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362108	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362108&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403532	136966170		CHEMBL1940510				ZINC73219533	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713050	CN1CCN(CCCN(Cc2ccccn2)C(=O)c2ccc(o2)-c2ccc(cc2)C#N)CC1	InChI=1S/C26H29N5O2/c1-29-15-17-30(18-16-29)13-4-14-31(20-23-5-2-3-12-28-23)26(32)25-11-10-24(33-25)22-8-6-21(19-27)7-9-22/h2-3,5-12H,4,13-18,20H2,1H3	PJYZHQNQPJJICP-UHFFFAOYSA-N	50362109	CHEMBL1940511	MAP kinase-activated protein kinase 2	Homo sapiens		 10000							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362109	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362109&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393088	136966171		CHEMBL1940511				ZINC73219536	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713051	O=C(N(Cc1ccccn1)C1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C23H22N4O2/c24-15-17-4-6-18(7-5-17)21-8-9-22(29-21)23(28)27(20-10-13-25-14-11-20)16-19-3-1-2-12-26-19/h1-9,12,20,25H,10-11,13-14,16H2	NYECKVJWFQGOSU-UHFFFAOYSA-N	50362110	CHEMBL1940512	MAP kinase-activated protein kinase 2	Homo sapiens		 10000							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362110	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362110&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400015	136966172		CHEMBL1940512				ZINC73219538	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713052	Cc1cccc(CN(C(=O)c2ccc(o2)-c2ccc(cc2)C#N)c2ccc(cc2)N2CCNCC2)n1	InChI=1S/C29H27N5O2/c1-21-3-2-4-24(32-21)20-34(26-11-9-25(10-12-26)33-17-15-31-16-18-33)29(35)28-14-13-27(36-28)23-7-5-22(19-30)6-8-23/h2-14,31H,15-18,20H2,1H3	RYTZZOXQALFERW-UHFFFAOYSA-N	50362111	CHEMBL1940513	MAP kinase-activated protein kinase 2	Homo sapiens		 79							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362111	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362111&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401826	136966173		CHEMBL1940513				ZINC82158444	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713053	O=C(N(Cc1ccc(cc1)-c1ccccc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C35H30N4O2/c36-24-26-6-12-30(13-7-26)33-18-19-34(41-33)35(40)39(32-16-14-31(15-17-32)38-22-20-37-21-23-38)25-27-8-10-29(11-9-27)28-4-2-1-3-5-28/h1-19,37H,20-23,25H2	CNORLXHSUGTBGL-UHFFFAOYSA-N	50362112	CHEMBL1940516	MAP kinase-activated protein kinase 2	Homo sapiens		 41							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362112	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362112&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401827	136966174		CHEMBL1940516				ZINC73224837	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713054	O=C(N(Cc1cccc(c1)-c1ccccc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C35H30N4O2/c36-24-26-9-11-29(12-10-26)33-17-18-34(41-33)35(40)39(32-15-13-31(14-16-32)38-21-19-37-20-22-38)25-27-5-4-8-30(23-27)28-6-2-1-3-7-28/h1-18,23,37H,19-22,25H2	LYARJBPEOJCWQO-UHFFFAOYSA-N	50362113	CHEMBL1940517	MAP kinase-activated protein kinase 2	Homo sapiens		 70							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362113	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362113&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403533	136966175		CHEMBL1940517				ZINC73224838	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713055	O=C(N(Cc1ccccc1-c1ccccc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C35H30N4O2/c36-24-26-10-12-28(13-11-26)33-18-19-34(41-33)35(40)39(31-16-14-30(15-17-31)38-22-20-37-21-23-38)25-29-8-4-5-9-32(29)27-6-2-1-3-7-27/h1-19,37H,20-23,25H2	QXGQSDPSWOLIIF-UHFFFAOYSA-N	50362114	CHEMBL1940518	MAP kinase-activated protein kinase 2	Homo sapiens		 9							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362114	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362114&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57394816	136966176		CHEMBL1940518				ZINC73239742	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713056	Fc1ccccc1-c1ccc(CN(C(=O)c2ccc(o2)-c2ccc(cc2)C#N)c2ccc(cc2)N2CCNCC2)cc1	InChI=1S/C35H29FN4O2/c36-32-4-2-1-3-31(32)27-9-7-26(8-10-27)24-40(30-15-13-29(14-16-30)39-21-19-38-20-22-39)35(41)34-18-17-33(42-34)28-11-5-25(23-37)6-12-28/h1-18,38H,19-22,24H2	JVXNVVMUOMDIGV-UHFFFAOYSA-N	50362115	CHEMBL1940519	MAP kinase-activated protein kinase 2	Homo sapiens		 1920							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362115	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362115&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400017	136966177		CHEMBL1940519				ZINC73239746	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713057	Fc1ccccc1-c1cccc(CN(C(=O)c2ccc(o2)-c2ccc(cc2)C#N)c2ccc(cc2)N2CCNCC2)c1	InChI=1S/C35H29FN4O2/c36-32-7-2-1-6-31(32)28-5-3-4-26(22-28)24-40(30-14-12-29(13-15-30)39-20-18-38-19-21-39)35(41)34-17-16-33(42-34)27-10-8-25(23-37)9-11-27/h1-17,22,38H,18-21,24H2	TXEHSUXDORJCGX-UHFFFAOYSA-N	50362116	CHEMBL1940520	MAP kinase-activated protein kinase 2	Homo sapiens		 1450							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362116	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362116&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398359	136966178		CHEMBL1940520				ZINC73239748	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713058	Fc1ccccc1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C35H29FN4O2/c36-32-8-4-3-7-31(32)30-6-2-1-5-27(30)24-40(29-15-13-28(14-16-29)39-21-19-38-20-22-39)35(41)34-18-17-33(42-34)26-11-9-25(23-37)10-12-26/h1-18,38H,19-22,24H2	BWYNPXQACMYPLB-UHFFFAOYSA-N	50362117	CHEMBL1940521	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362117	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362117&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401828	136966179		CHEMBL1940521				ZINC73239750	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713059	O=C(N(Cc1ccc(cc1)-c1ccncc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C34H29N5O2/c35-23-25-1-7-29(8-2-25)32-13-14-33(41-32)34(40)39(31-11-9-30(10-12-31)38-21-19-37-20-22-38)24-26-3-5-27(6-4-26)28-15-17-36-18-16-28/h1-18,37H,19-22,24H2	VYMLKBPAPJLSOY-UHFFFAOYSA-N	50362118	CHEMBL1940522	MAP kinase-activated protein kinase 2	Homo sapiens		 128							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362118&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391312	136966180		CHEMBL1940522				ZINC73239754	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713060	O=C(N(Cc1cccc(c1)-c1ccncc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C34H29N5O2/c35-23-25-4-6-28(7-5-25)32-12-13-33(41-32)34(40)39(31-10-8-30(9-11-31)38-20-18-37-19-21-38)24-26-2-1-3-29(22-26)27-14-16-36-17-15-27/h1-17,22,37H,18-21,24H2	IHQVLYIGDGYRJA-UHFFFAOYSA-N	50362119	CHEMBL1940523	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362119	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362119&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401829	136966181		CHEMBL1940523				ZINC73220446	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713061	O=C(N(Cc1ccccc1-c1ccncc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C34H29N5O2/c35-23-25-5-7-27(8-6-25)32-13-14-33(41-32)34(40)39(30-11-9-29(10-12-30)38-21-19-37-20-22-38)24-28-3-1-2-4-31(28)26-15-17-36-18-16-26/h1-18,37H,19-22,24H2	SIBCKUSTTDOGRO-UHFFFAOYSA-N	50362120	CHEMBL1940524	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362120	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362120&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57396580	136966182		CHEMBL1940524				ZINC73220451	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713062	Cc1ccccc1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C36H32N4O2/c1-26-6-2-4-8-32(26)33-9-5-3-7-29(33)25-40(31-16-14-30(15-17-31)39-22-20-38-21-23-39)36(41)35-19-18-34(42-35)28-12-10-27(24-37)11-13-28/h2-19,38H,20-23,25H2,1H3	MNXGGPGZBSMPFE-UHFFFAOYSA-N	50362121	CHEMBL1940643	MAP kinase-activated protein kinase 2	Homo sapiens		 285							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362121	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362121&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393102	136966183		CHEMBL1940643				ZINC73219322	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713063	Cc1cccc(C)c1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C37H34N4O2/c1-26-6-5-7-27(2)36(26)33-9-4-3-8-30(33)25-41(32-16-14-31(15-17-32)40-22-20-39-21-23-40)37(42)35-19-18-34(43-35)29-12-10-28(24-38)11-13-29/h3-19,39H,20-23,25H2,1-2H3	MBVJKLPCZMYYJA-UHFFFAOYSA-N	50362122	CHEMBL1938419	MAP kinase-activated protein kinase 2	Homo sapiens		 258							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362122	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362122&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395930	136966184		CHEMBL1938419				ZINC73220184	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713064	Cc1noc(C)c1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C34H31N5O3/c1-23-33(24(2)42-37-23)30-6-4-3-5-27(30)22-39(29-13-11-28(12-14-29)38-19-17-36-18-20-38)34(40)32-16-15-31(41-32)26-9-7-25(21-35)8-10-26/h3-16,36H,17-20,22H2,1-2H3	AKSBJSCHRGVNRM-UHFFFAOYSA-N	50362123	CHEMBL1940644	MAP kinase-activated protein kinase 2	Homo sapiens		 21							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362123	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362123&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391323	136966185		CHEMBL1940644				ZINC73224780	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713065	O=C(N(Cc1ccccc1-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C36H29N5O2/c37-23-26-5-9-28(10-6-26)33-4-2-1-3-30(33)25-41(32-15-13-31(14-16-32)40-21-19-39-20-22-40)36(42)35-18-17-34(43-35)29-11-7-27(24-38)8-12-29/h1-18,39H,19-22,25H2	ZTKGVNVXGQXYOD-UHFFFAOYSA-N	50362124	CHEMBL1940645	MAP kinase-activated protein kinase 2	Homo sapiens		 8							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362124	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362124&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391324	136966186		CHEMBL1940645				ZINC73224781	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713066	O=C(N(Cc1ccccc1-c1cccc(c1)C#N)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C36H29N5O2/c37-23-26-8-10-28(11-9-26)34-16-17-35(43-34)36(42)41(32-14-12-31(13-15-32)40-20-18-39-19-21-40)25-30-5-1-2-7-33(30)29-6-3-4-27(22-29)24-38/h1-17,22,39H,18-21,25H2	LSCFHLOXDLXHHJ-UHFFFAOYSA-N	50362125	CHEMBL1940646	MAP kinase-activated protein kinase 2	Homo sapiens		 19							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362125	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362125&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400031	136966187		CHEMBL1940646				ZINC73224782	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713067	COc1cccc(c1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C36H32N4O3/c1-42-32-7-4-6-28(23-32)33-8-3-2-5-29(33)25-40(31-15-13-30(14-16-31)39-21-19-38-20-22-39)36(41)35-18-17-34(43-35)27-11-9-26(24-37)10-12-27/h2-18,23,38H,19-22,25H2,1H3	ONBBGDWEEADKDE-UHFFFAOYSA-N	50362126	CHEMBL1940647	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362126	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362126&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401844	136966188		CHEMBL1940647				ZINC73224783	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713068	O=C(N(Cc1ccccc1-c1cccnc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C34H29N5O2/c35-22-25-7-9-26(10-8-25)32-15-16-33(41-32)34(40)39(30-13-11-29(12-14-30)38-20-18-36-19-21-38)24-28-4-1-2-6-31(28)27-5-3-17-37-23-27/h1-17,23,36H,18-21,24H2	DMPYIDWDIPMNMX-UHFFFAOYSA-N	50362127	CHEMBL1940648	MAP kinase-activated protein kinase 2	Homo sapiens		 9							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362127	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362127&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57403552	136966189		CHEMBL1940648				ZINC73222356	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713069	O=C(N(Cc1ccccc1-c1ccccn1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C34H29N5O2/c35-23-25-8-10-26(11-9-25)32-16-17-33(41-32)34(40)39(29-14-12-28(13-15-29)38-21-19-36-20-22-38)24-27-5-1-2-6-30(27)31-7-3-4-18-37-31/h1-18,36H,19-22,24H2	MBETWUSANGLLRC-UHFFFAOYSA-N	50362128	CHEMBL1940649	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362128	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362128&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398374	136966190		CHEMBL1940649				ZINC73240611	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713070	O=C(N(Cc1ccccc1-c1cncnc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C33H28N6O2/c34-19-24-5-7-25(8-6-24)31-13-14-32(41-31)33(40)39(29-11-9-28(10-12-29)38-17-15-35-16-18-38)22-26-3-1-2-4-30(26)27-20-36-23-37-21-27/h1-14,20-21,23,35H,15-18,22H2	UAKHJDUBVXTVHZ-UHFFFAOYSA-N	50362129	CHEMBL1940650	MAP kinase-activated protein kinase 2	Homo sapiens		 27							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362129	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362129&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391325	136966191		CHEMBL1940650				ZINC73240613	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713071	COc1cncc(c1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C35H31N5O3/c1-42-31-20-28(22-38-23-31)32-5-3-2-4-27(32)24-40(30-12-10-29(11-13-30)39-18-16-37-17-19-39)35(41)34-15-14-33(43-34)26-8-6-25(21-36)7-9-26/h2-15,20,22-23,37H,16-19,24H2,1H3	ZLXTUHCNUSBTSP-UHFFFAOYSA-N	50362130	CHEMBL1940651	MAP kinase-activated protein kinase 2	Homo sapiens		 20							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362130	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362130&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393103	136966192		CHEMBL1940651				ZINC73240615	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713072	COc1ccncc1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C35H31N5O3/c1-42-33-16-17-38-23-31(33)30-5-3-2-4-27(30)24-40(29-12-10-28(11-13-29)39-20-18-37-19-21-39)35(41)34-15-14-32(43-34)26-8-6-25(22-36)7-9-26/h2-17,23,37H,18-21,24H2,1H3	XSGBGNIHTMRFKW-UHFFFAOYSA-N	50362131	CHEMBL1940652	MAP kinase-activated protein kinase 2	Homo sapiens		 8							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362131	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362131&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56950243	136966193		CHEMBL1940652				ZINC73240618	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713073	COc1ccc(cn1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C35H31N5O3/c1-42-34-17-10-27(23-38-34)31-5-3-2-4-28(31)24-40(30-13-11-29(12-14-30)39-20-18-37-19-21-39)35(41)33-16-15-32(43-33)26-8-6-25(22-36)7-9-26/h2-17,23,37H,18-21,24H2,1H3	RHRROJDGXFJBGI-UHFFFAOYSA-N	50362132	CHEMBL1940653	MAP kinase-activated protein kinase 2	Homo sapiens		 43							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362132	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362132&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57400032	136966194		CHEMBL1940653				ZINC73240620	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713074	COc1cc(ccn1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C35H31N5O3/c1-42-34-22-27(16-17-38-34)31-5-3-2-4-28(31)24-40(30-12-10-29(11-13-30)39-20-18-37-19-21-39)35(41)33-15-14-32(43-33)26-8-6-25(23-36)7-9-26/h2-17,22,37H,18-21,24H2,1H3	YLRPKLKBKJDOGT-UHFFFAOYSA-N	50362133	CHEMBL1940654	MAP kinase-activated protein kinase 2	Homo sapiens		 24							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362133	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362133&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57394830	136966195		CHEMBL1940654				ZINC73224638	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713075	COc1ncc(cn1)-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C34H30N6O3/c1-42-34-37-21-27(22-38-34)30-5-3-2-4-26(30)23-40(29-12-10-28(11-13-29)39-18-16-36-17-19-39)33(41)32-15-14-31(43-32)25-8-6-24(20-35)7-9-25/h2-15,21-22,36H,16-19,23H2,1H3	LGKZZXGYBQAUNW-UHFFFAOYSA-N	50362134	CHEMBL1940655	MAP kinase-activated protein kinase 2	Homo sapiens		 52							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362134	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362134&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391326	136966196		CHEMBL1940655				ZINC73220585	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713076	COc1ccccc1-c1ccccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C36H32N4O3/c1-42-34-9-5-4-8-32(34)31-7-3-2-6-28(31)25-40(30-16-14-29(15-17-30)39-22-20-38-21-23-39)36(41)35-19-18-33(43-35)27-12-10-26(24-37)11-13-27/h2-19,38H,20-23,25H2,1H3	ZSLFCLPPHVEICK-UHFFFAOYSA-N	50362135	CHEMBL1940656	MAP kinase-activated protein kinase 2	Homo sapiens		 20							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362135	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362135&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393104	136966197		CHEMBL1940656				ZINC73220588	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713077	COc1ccccc1-c1ncccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C35H31N5O3/c1-42-32-7-3-2-6-30(32)34-27(5-4-18-38-34)24-40(29-14-12-28(13-15-29)39-21-19-37-20-22-39)35(41)33-17-16-31(43-33)26-10-8-25(23-36)9-11-26/h2-18,37H,19-22,24H2,1H3	DRABYIDPCBRDCS-UHFFFAOYSA-N	50362136	CHEMBL1940657	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362136	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362136&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398375	136966198		CHEMBL1940657				ZINC73220590	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713078	COc1ccncc1-c1ncccc1CN(C(=O)c1ccc(o1)-c1ccc(cc1)C#N)c1ccc(cc1)N1CCNCC1	InChI=1S/C34H30N6O3/c1-42-31-14-16-37-22-29(31)33-26(3-2-15-38-33)23-40(28-10-8-27(9-11-28)39-19-17-36-18-20-39)34(41)32-13-12-30(43-32)25-6-4-24(21-35)5-7-25/h2-16,22,36H,17-20,23H2,1H3	ZCYJAOOUGMNXOF-UHFFFAOYSA-N	50362137	CHEMBL1940658	MAP kinase-activated protein kinase 2	Homo sapiens		 9							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362137	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362137&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57398376	136966199		CHEMBL1940658				ZINC73220594	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713079	O=C(N(Cc1cccnc1-c1cncnc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(cc1)C#N	InChI=1S/C32H27N7O2/c33-18-23-3-5-24(6-4-23)29-11-12-30(41-29)32(40)39(28-9-7-27(8-10-28)38-16-14-34-15-17-38)21-25-2-1-13-37-31(25)26-19-35-22-36-20-26/h1-13,19-20,22,34H,14-17,21H2	WGYUUPMIUJTERK-UHFFFAOYSA-N	50362138	CHEMBL1940659	MAP kinase-activated protein kinase 2	Homo sapiens		 100							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362138	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362138&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57393105	136966200		CHEMBL1940659				ZINC73220429	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713080	O=C(N(Cc1ccccc1-c1ccccc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(nc1)C#N	InChI=1S/C34H29N5O2/c35-22-28-11-10-26(23-37-28)32-16-17-33(41-32)34(40)39(30-14-12-29(13-15-30)38-20-18-36-19-21-38)24-27-8-4-5-9-31(27)25-6-2-1-3-7-25/h1-17,23,36H,18-21,24H2	QWQSWRHYUMLKRW-UHFFFAOYSA-N	50362139	CHEMBL1940660	MAP kinase-activated protein kinase 2	Homo sapiens		 258							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362139	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362139&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57394831	136966201		CHEMBL1940660				ZINC82157876	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713081	O=C(N(Cc1ccccc1-c1cccnc1)c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(nc1)C#N	InChI=1S/C33H28N6O2/c34-20-27-8-7-25(22-37-27)31-13-14-32(41-31)33(40)39(29-11-9-28(10-12-29)38-18-16-35-17-19-38)23-26-4-1-2-6-30(26)24-5-3-15-36-21-24/h1-15,21-22,35H,16-19,23H2	MAVLBZSYPTWIKY-UHFFFAOYSA-N	50362140	CHEMBL1940661	MAP kinase-activated protein kinase 2	Homo sapiens		 177							ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362140	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362140&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57391327	136966202		CHEMBL1940661				ZINC73224160	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713082	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens				 350					ChEMBL	10.1016/j.bmcl.2011.11.074	10.7270/Q2R78FNS	22169260			Huang, X; Zhu, X; Chen, X; Zhou, W; Xiao, D; Degrado, S; Aslanian, R; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713164	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	CAIGVNVLJGDZSF-UHFFFAOYSA-N	50362169	CHEMBL1938680	MAP kinase-activated protein kinase 2	Homo sapiens		 5500							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362169&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401151	136966231		CHEMBL1938680				ZINC73224553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713165	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713166	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3NC(=O)c2o1)N1CCNCC1	InChI=1S/C22H20ClN3O2/c23-17-3-1-14(2-4-17)20-13-16-11-15-12-18(26-9-7-24-8-10-26)5-6-19(15)25-22(27)21(16)28-20/h1-6,12-13,24H,7-11H2,(H,25,27)	FUZHDIGYHQYSHU-UHFFFAOYSA-N	50362170	CHEMBL1938682	MAP kinase-activated protein kinase 2	Homo sapiens		 96							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362170&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251635	136966232		CHEMBL1938682				ZINC82158225	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713167	O=C1Nc2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C23H20N4O2/c24-14-15-1-3-16(4-2-15)21-13-18-11-17-12-19(27-9-7-25-8-10-27)5-6-20(17)26-23(28)22(18)29-21/h1-6,12-13,25H,7-11H2,(H,26,28)	YWYHWXBABMENQU-UHFFFAOYSA-N	50362171	CHEMBL1938683	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362171&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251321	136966233		CHEMBL1938683				ZINC82158226	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713168	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1	InChI=1S/C24H21ClN4O/c25-19-3-1-16(2-4-19)22-15-18-13-17-14-20(28-10-7-26-8-11-28)5-6-21(17)29-12-9-27-24(29)23(18)30-22/h1-6,9,12,14-15,26H,7-8,10-11,13H2	MEYZYVFRRYUEJP-UHFFFAOYSA-N	50362172	CHEMBL1938684	MAP kinase-activated protein kinase 2	Homo sapiens		 7							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362172&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395938	136966234		CHEMBL1938684				ZINC82158227	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713169	N#Cc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1	InChI=1S/C25H21N5O/c26-16-17-1-3-18(4-2-17)23-15-20-13-19-14-21(29-10-7-27-8-11-29)5-6-22(19)30-12-9-28-25(30)24(20)31-23/h1-6,9,12,14-15,27H,7-8,10-11,13H2	HELAOPSUGMMSIW-UHFFFAOYSA-N	50362173	CHEMBL1938685	MAP kinase-activated protein kinase 2	Homo sapiens		 2.9							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362173&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56950796	136966235		CHEMBL1938685				ZINC73224224	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713170	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1	InChI=1S/C23H20ClN5O/c24-18-3-1-15(2-4-18)21-13-17-11-16-12-19(28-9-7-25-8-10-28)5-6-20(16)29-14-26-27-23(29)22(17)30-21/h1-6,12-14,25H,7-11H2	CPKRQGKZSQPZPY-UHFFFAOYSA-N	50362174	CHEMBL1938686	MAP kinase-activated protein kinase 2	Homo sapiens		 9.3							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362174&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57392443	136966236		CHEMBL1938686				ZINC73224225	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713171	N#Cc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1	InChI=1S/C24H20N6O/c25-14-16-1-3-17(4-2-16)22-13-19-11-18-12-20(29-9-7-26-8-10-29)5-6-21(18)30-15-27-28-24(30)23(19)31-22/h1-6,12-13,15,26H,7-11H2	MANUYYBKDVBEBT-UHFFFAOYSA-N	50362175	CHEMBL1938687	MAP kinase-activated protein kinase 2	Homo sapiens		 3.8							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362175&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56950797	136966237		CHEMBL1938687				ZINC73224226	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713172	Fc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1	InChI=1S/C23H20FN5O/c24-18-3-1-15(2-4-18)21-13-17-11-16-12-19(28-9-7-25-8-10-28)5-6-20(16)29-14-26-27-23(29)22(17)30-21/h1-6,12-14,25H,7-11H2	ZCXYZALUIUCPGT-UHFFFAOYSA-N	50362176	CHEMBL1938688	MAP kinase-activated protein kinase 2	Homo sapiens		 15							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362176	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362176&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395939	136966238		CHEMBL1938688				ZINC73224227	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713173	Cc1cnc2-c3oc(cc3Cc3cc(ccc3-n12)N1CCNCC1)-c1ccc(Cl)cc1	InChI=1S/C25H23ClN4O/c1-16-15-28-25-24-19(14-23(31-24)17-2-4-20(26)5-3-17)12-18-13-21(6-7-22(18)30(16)25)29-10-8-27-9-11-29/h2-7,13-15,27H,8-12H2,1H3	CDAOXEMWBDQTEE-UHFFFAOYSA-N	50362177	CHEMBL1938689	MAP kinase-activated protein kinase 2	Homo sapiens		 9.2							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362177&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57392444	136966239		CHEMBL1938689				ZINC73225055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713174	Cc1nnc2-c3oc(cc3Cc3cc(ccc3-n12)N1CCNCC1)-c1ccc(Cl)cc1	InChI=1S/C24H22ClN5O/c1-15-27-28-24-23-18(14-22(31-23)16-2-4-19(25)5-3-16)12-17-13-20(6-7-21(17)30(15)24)29-10-8-26-9-11-29/h2-7,13-14,26H,8-12H2,1H3	FHTHRPFHYIVJLA-UHFFFAOYSA-N	50362178	CHEMBL1938690	MAP kinase-activated protein kinase 2	Homo sapiens		 880							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362178	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362178&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57392445	136966240		CHEMBL1938690				ZINC73240412	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713175	Clc1ccc(cc1)-c1cc2COc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1	InChI=1S/C24H21ClN4O2/c25-18-3-1-16(2-4-18)21-13-17-15-30-22-14-19(28-10-7-26-8-11-28)5-6-20(22)29-12-9-27-24(29)23(17)31-21/h1-6,9,12-14,26H,7-8,10-11,15H2	RFJBIIHNLZVSQS-UHFFFAOYSA-N	50362179	CHEMBL1938691	MAP kinase-activated protein kinase 2	Homo sapiens		 18							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362179	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362179&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57392446	136966241		CHEMBL1938691				ZINC73240414	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713176	Clc1ccc(cc1)-c1cc2COc3cc(ccc3NC(=O)c2o1)N1CCNCC1	InChI=1S/C22H20ClN3O3/c23-16-3-1-14(2-4-16)19-11-15-13-28-20-12-17(26-9-7-24-8-10-26)5-6-18(20)25-22(27)21(15)29-19/h1-6,11-12,24H,7-10,13H2,(H,25,27)	ULONVLUMOUFCID-UHFFFAOYSA-N	50362180	CHEMBL1938692	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362180	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362180&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57394157	136966242		CHEMBL1938692				ZINC73240416	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713177	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	CAIGVNVLJGDZSF-UHFFFAOYSA-N	50362169	CHEMBL1938680	MAP kinase-activated protein kinase 2	Homo sapiens				 2000					ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362169&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401151	136966231		CHEMBL1938680				ZINC73224553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713178	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens				 350					ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713179	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1	InChI=1S/C24H21ClN4O/c25-19-3-1-16(2-4-19)22-15-18-13-17-14-20(28-10-7-26-8-11-28)5-6-21(17)29-12-9-27-24(29)23(18)30-22/h1-6,9,12,14-15,26H,7-8,10-11,13H2	MEYZYVFRRYUEJP-UHFFFAOYSA-N	50362172	CHEMBL1938684	MAP kinase-activated protein kinase 2	Homo sapiens				 1500					ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362172	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362172&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57395938	136966234		CHEMBL1938684				ZINC82158227	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713180	N#Cc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3ccnc3-c2o1)N1CCNCC1	InChI=1S/C25H21N5O/c26-16-17-1-3-18(4-2-17)23-15-20-13-19-14-21(29-10-7-27-8-11-29)5-6-22(19)30-12-9-28-25(30)24(20)31-23/h1-6,9,12,14-15,27H,7-8,10-11,13H2	HELAOPSUGMMSIW-UHFFFAOYSA-N	50362173	CHEMBL1938685	MAP kinase-activated protein kinase 2	Homo sapiens				 260					ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362173	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362173&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56950796	136966235		CHEMBL1938685				ZINC73224224	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713181	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1	InChI=1S/C23H20ClN5O/c24-18-3-1-15(2-4-18)21-13-17-11-16-12-19(28-9-7-25-8-10-28)5-6-20(16)29-14-26-27-23(29)22(17)30-21/h1-6,12-14,25H,7-11H2	CPKRQGKZSQPZPY-UHFFFAOYSA-N	50362174	CHEMBL1938686	MAP kinase-activated protein kinase 2	Homo sapiens				 2100					ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362174	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362174&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57392443	136966236		CHEMBL1938686				ZINC73224225	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713182	N#Cc1ccc(cc1)-c1cc2Cc3cc(ccc3-n3cnnc3-c2o1)N1CCNCC1	InChI=1S/C24H20N6O/c25-14-16-1-3-17(4-2-16)22-13-19-11-18-12-20(29-9-7-26-8-10-29)5-6-21(18)30-15-27-28-24(30)23(19)31-22/h1-6,12-13,15,26H,7-11H2	MANUYYBKDVBEBT-UHFFFAOYSA-N	50362175	CHEMBL1938687	MAP kinase-activated protein kinase 2	Homo sapiens				 260					ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362175	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362175&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56950797	136966237		CHEMBL1938687				ZINC73224226	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50713183	Cc1cnc2-c3oc(cc3Cc3cc(ccc3-n12)N1CCNCC1)-c1ccc(Cl)cc1	InChI=1S/C25H23ClN4O/c1-16-15-28-25-24-19(14-23(31-24)17-2-4-20(26)5-3-17)12-18-13-21(6-7-22(18)30(16)25)29-10-8-27-9-11-29/h2-7,13-15,27H,8-12H2,1H3	CDAOXEMWBDQTEE-UHFFFAOYSA-N	50362177	CHEMBL1938689	MAP kinase-activated protein kinase 2	Homo sapiens				 2500					ChEMBL	10.1016/j.bmcl.2011.11.113	10.7270/Q23J3DDJ	22182499			Rao, AU; Xiao, D; Huang, X; Zhou, W; Fossetta, J; Lundell, D; Tian, F; Trivedi, P; Aslanian, R; Palani, A	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362177	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362177&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57392444	136966239		CHEMBL1938689				ZINC73225055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50829232	N#CC(c1nc2ccccc2s1)c1ccnc(NCCc2cccnc2)n1	InChI=1S/C20H16N6S/c21-12-15(19-25-17-5-1-2-6-18(17)27-19)16-8-11-24-20(26-16)23-10-7-14-4-3-9-22-13-14/h1-6,8-9,11,13,15H,7,10H2,(H,23,24,26)	RCYPVQCPYKNSTG-UHFFFAOYSA-N	50169959	2-(benzo[d]thiazol-2(3H)-ylidene)-2-(2-(2-(pyridin-3-yl)ethylamino)pyrimidin-4-yl)acetonitrile::AS-601245::AS601245::CHEMBL1788116::CHEMBL191384::[3H-Benzothiazol-(2Z)-ylidene]-[2-(2-pyridin-3-yl-ethylamino)-pyrimidin-4-yl]-acetonitrile	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm0310986	10.7270/Q2K9389G	15999997			Gaillard, P; Jeanclaude-Etter, I; Ardissone, V; Arkinstall, S; Cambet, Y; Camps, M; Chabert, C; Church, D; Cirillo, R; Gretener, D; Halazy, S; Nichols, A; Szyndralewiez, C; Vitte, PA; Gotteland, JP	Serono Pharmaceutical Research Institute	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50169959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50169959&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	JN5	3CY3	10109823	104054707		CHEMBL1788116CHEMBL191384		5997		ZINC13647791	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50840560	C[C@@H]1C[C@H]2CN1CCn1[nH]c3c(cccc3c1=O)-c1nc3c(O2)cccc3[nH]c1=O	InChI=1S/C22H21N5O3/c1-12-10-13-11-26(12)8-9-27-22(29)15-5-2-4-14(18(15)25-27)19-21(28)23-16-6-3-7-17(30-13)20(16)24-19/h2-7,12-13,25H,8-11H2,1H3,(H,23,28)/t12-,13+/m1/s1	KBLPHMRCKHFBJB-OLZOCXBDSA-N	50192071	(13R,15S)-13-methyl-16-oxa-8,9,12,22,24-pentaazahexacyclo[15.6.2.1^{6,9}.1^{12,15}.0^{2,7}.0^{21,25}]heptacosa-1(24),2,4,6(27),7,17(25),18,20,22-nonaene-23,27-diol::CHEMBL215803	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL	10.1016/j.bmcl.2006.07.026	10.7270/Q2K35VF0	16876403			Kawanishi, N; Sugimoto, T; Shibata, J; Nakamura, K; Masutani, K; Ikuta, M; Hirai, H	Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50192071	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50192071&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	1CD	2DS1	16046126	104075026		CHEMBL215803	DB06888			ZINC36770746	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50851728	Clc1cc2NC(=O)Nc3cnc(C#N)c(OCCCCOc2cc1NCc1cncs1)n3	InChI=1S/C20H18ClN7O3S/c21-13-5-15-17(6-14(13)24-9-12-8-23-11-32-12)30-3-1-2-4-31-19-16(7-22)25-10-18(27-19)28-20(29)26-15/h5-6,8,10-11,24H,1-4,9H2,(H2,26,27,28,29)	AZTMYWWWILJAKW-UHFFFAOYSA-N	50224883	7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,16-dioxa-2,4,19,21-tetraaza-tricyclo[15.3.1.0*5,10*]henicosa-1(21),5,7,9,17,19-hexaene-18-crbonitrile::CHEMBL248757	MAP kinase-activated protein kinase 2	Homo sapiens	 3886								ChEMBL	10.1016/j.bmcl.2007.09.063	10.7270/Q2X067WT	17935989			Tao, ZF; Chen, Z; Bui, MH; Kovar, P; Johnson, E; Bouska, J; Zhang, H; Rosenberg, S; Sowin, T; Lin, NH	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50224883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50224883&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44444843	104096404		CHEMBL248757				ZINC28963230	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862775	CC1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC(C)n4c3c2)n1	InChI=1S/C24H27N5O3S/c1-13-3-7-17(8-4-13)26-22(31)18-12-33-24(27-18)28-21(30)16-6-5-15-9-20-23(32)25-11-14(2)29(20)19(15)10-16/h5-6,9-10,12-14,17H,3-4,7-8,11H2,1-2H3,(H,25,32)(H,26,31)(H,27,28,30)	NLDBMECQYGNKCF-UHFFFAOYSA-N	50374691	CHEMBL437033	MAP kinase-activated protein kinase 2	Homo sapiens		 45							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374691	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374691&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454704	160853781		CHEMBL437033				ZINC29127920	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862776	CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NC1CCOCC1	InChI=1S/C22H23N5O4S/c1-12-10-23-21(30)18-8-13-2-3-14(9-17(13)27(12)18)19(28)26-22-25-16(11-32-22)20(29)24-15-4-6-31-7-5-15/h2-3,8-9,11-12,15H,4-7,10H2,1H3,(H,23,30)(H,24,29)(H,25,26,28)	SBSVNMNWUNRGBH-UHFFFAOYSA-N	50374692	CHEMBL272072	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374692	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374692&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454706	160853782		CHEMBL272072				ZINC29127925	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862777	CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NC1CCN(C)CC1	InChI=1S/C23H26N6O3S/c1-13-11-24-22(32)19-9-14-3-4-15(10-18(14)29(13)19)20(30)27-23-26-17(12-33-23)21(31)25-16-5-7-28(2)8-6-16/h3-4,9-10,12-13,16H,5-8,11H2,1-2H3,(H,24,32)(H,25,31)(H,26,27,30)	DZCMVCGUUJNMQE-UHFFFAOYSA-N	50374693	CHEMBL271309	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374693	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374693&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454732	160853783		CHEMBL271309				ZINC29127968	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862778	CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NC1CCCCC1	InChI=1S/C23H25N5O3S/c1-13-11-24-22(31)19-9-14-7-8-15(10-18(14)28(13)19)20(29)27-23-26-17(12-32-23)21(30)25-16-5-3-2-4-6-16/h7-10,12-13,16H,2-6,11H2,1H3,(H,24,31)(H,25,30)(H,26,27,29)	AXEOOGDKIBIWSA-UHFFFAOYSA-N	50374694	CHEMBL409727	MAP kinase-activated protein kinase 2	Homo sapiens		 20							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374694	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374694&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454733	160853784		CHEMBL409727				ZINC29127971	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862781	CC(C)(C)CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1	InChI=1S/C29H36N6O3S/c1-28(2,3)17-34-11-7-20(8-12-34)31-25(37)21-15-39-27(32-21)33-24(36)19-6-5-18-13-23-26(38)30-16-29(9-4-10-29)35(23)22(18)14-19/h5-6,13-15,20H,4,7-12,16-17H2,1-3H3,(H,30,38)(H,31,37)(H,32,33,36)	MJQUKUIDCUNAAB-UHFFFAOYSA-N	50374681	CHEMBL257834	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374681&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24882562	160853771		CHEMBL257834				ZINC29127774	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862782	CC(C)(C)CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1	InChI=1S/C29H36N6O3S/c1-28(2,3)17-34-11-7-20(8-12-34)31-25(37)21-15-39-27(32-21)33-24(36)19-6-5-18-13-23-26(38)30-16-29(9-4-10-29)35(23)22(18)14-19/h5-6,13-15,20H,4,7-12,16-17H2,1-3H3,(H,30,38)(H,31,37)(H,32,33,36)	MJQUKUIDCUNAAB-UHFFFAOYSA-N	50374681	CHEMBL257834	MAP kinase-activated protein kinase 2	Homo sapiens		 710							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374681&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24882562	160853771		CHEMBL257834				ZINC29127774	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862783	CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NC1CCN(C)CC1	InChI=1S/C23H26N6O3S/c1-12-10-24-22(32)19-18(12)15-9-13(3-4-16(15)26-19)20(30)28-23-27-17(11-33-23)21(31)25-14-5-7-29(2)8-6-14/h3-4,9,11-12,14,26H,5-8,10H2,1-2H3,(H,24,32)(H,25,31)(H,27,28,30)	HPMBJLMHMXBQEW-UHFFFAOYSA-N	50374695	CHEMBL246301	MAP kinase-activated protein kinase 2	Homo sapiens		 10							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374695	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374695&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			23661566	160853785		CHEMBL246301				ZINC28902421	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50870928	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(cc23)S(=O)(=O)Cc2c(Cl)cccc2Cl)c(C)c1C(=O)N1CCC[C@@H]1CN1CCCC1	InChI=1S/C32H34Cl2N4O4S/c1-19-29(35-20(2)30(19)32(40)38-14-6-7-21(38)17-37-12-3-4-13-37)16-24-23-15-22(10-11-28(23)36-31(24)39)43(41,42)18-25-26(33)8-5-9-27(25)34/h5,8-11,15-16,21,35H,3-4,6-7,12-14,17-18H2,1-2H3,(H,36,39)/b24-16-/t21-/m1/s1	OYONTEXKYJZFHA-SSHUPFPWSA-N	50242737	(R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimethyl-4-(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-1H-pyrrol-2-yl)methylene)indolin-2-one::CHEMBL450786::PHA-665752::TCMDC-125885	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1073/pnas.0707498104	10.7270/Q24X58QS	18077425			McDermott, U; Sharma, SV; Dowell, L; Greninger, P; Montagut, C; Lamb, J; Archibald, H; Raudales, R; Tam, A; Lee, D; Rothenberg, SM; Supko, JG; Sordella, R; Ulkus, LE; Iafrate, AJ; Maheswaran, S; Njauw, CN; Tsao, H; Drew, L; Hanke, JH; Ma, XJ; Erlander, MG; Gray, NS; Haber, DA; Settleman, J	Harvard Medical School	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50242737	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50242737&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10461815	104099202		CHEMBL450786		5700		ZINC03938668	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50864002	Nc1nccn2c(nc(-c3ccc4ccc(nc4c3)-c3ccccc3)c12)[C@@H]1C[C@H](CN2CCC2)C1	InChI=1S/C29H28N6/c30-28-27-26(22-8-7-21-9-10-24(32-25(21)17-22)20-5-2-1-3-6-20)33-29(35(27)14-11-31-28)23-15-19(16-23)18-34-12-4-13-34/h1-3,5-11,14,17,19,23H,4,12-13,15-16,18H2,(H2,30,31)/t19-,23+	FUGZYLOFWXVFQU-OKDJAKQTSA-N	50336316	CHEMBL410659::cis-3-(3-(azetidin-1-ylmethyl)cyclobutyl)-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine::cis-3-(3-azetidin-1-ylmethylcyclobutyl)-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-ylamine	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2007.10.061	10.7270/Q2WH2QVH	17983756			Mulvihill, MJ; Ji, QS; Coate, HR; Cooke, A; Dong, H; Feng, L; Foreman, K; Rosenfeld-Franklin, M; Honda, A; Mak, G; Mulvihill, KM; Nigro, AI; O'Connor, M; Pirrit, C; Steinig, AG; Siu, K; Stolz, KM; Sun, Y; Tavares, PA; Yao, Y; Gibson, NW	OSI Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50336316	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50336316&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11583459	125086418		CHEMBL410659				ZINC29059823	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50865139	CN(c1cccnc1)c1cc2c(Nc3ccc(F)c(Cl)c3)c(cnc2cn1)C#N	InChI=1S/C21H14ClFN6/c1-29(15-3-2-6-25-11-15)20-8-16-19(12-27-20)26-10-13(9-24)21(16)28-14-4-5-18(23)17(22)7-14/h2-8,10-12H,1H3,(H,26,28)	CUIQYXHABOOZFA-UHFFFAOYSA-N	50375665	CHEMBL261238	MAP kinase-activated protein kinase 2	Homo sapiens		 110000000							ChEMBL	10.1073/pnas.0708800104	10.7270/Q2DB82RH	18077363			Fedorov, O; Marsden, B; Pogacic, V; Rellos, P; Muller, S; Bullock, AN; Schwaller, J; Sundstrom, M; Knapp, S	University of Oxford	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50375665	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50375665&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44450544	160854755		CHEMBL261238				ZINC29055733	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862762	CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1nc(cs1)C(=O)NC1CCCCC1	InChI=1S/C23H25N5O3S/c1-12-10-24-22(31)19-18(12)15-9-13(7-8-16(15)26-19)20(29)28-23-27-17(11-32-23)21(30)25-14-5-3-2-4-6-14/h7-9,11-12,14,26H,2-6,10H2,1H3,(H,24,31)(H,25,30)(H,27,28,29)	WIVODQGHXOFCFL-UHFFFAOYSA-N	50374678	CHEMBL246300	MAP kinase-activated protein kinase 2	Homo sapiens		 44							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374678&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44143538	160853768		CHEMBL246300				ZINC28902401	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862763	O=C(NC1CCN(Cc2ccccc2)CC1)c1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1	InChI=1S/C31H32N6O3S/c38-27(22-8-7-21-15-26-29(40)32-19-31(11-4-12-31)37(26)25(21)16-22)35-30-34-24(18-41-30)28(39)33-23-9-13-36(14-10-23)17-20-5-2-1-3-6-20/h1-3,5-8,15-16,18,23H,4,9-14,17,19H2,(H,32,40)(H,33,39)(H,34,35,38)	QXQDLEUEUWFHGW-UHFFFAOYSA-N	50374679	CHEMBL403258	MAP kinase-activated protein kinase 2	Homo sapiens		 3							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374679&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454601	160853769		CHEMBL403258				ZINC29127735	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862764	CC1(C)CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NC1CCN(Cc2ccccc2)CC1	InChI=1S/C30H32N6O3S/c1-30(2)18-31-28(39)25-14-20-8-9-21(15-24(20)36(25)30)26(37)34-29-33-23(17-40-29)27(38)32-22-10-12-35(13-11-22)16-19-6-4-3-5-7-19/h3-9,14-15,17,22H,10-13,16,18H2,1-2H3,(H,31,39)(H,32,38)(H,33,34,37)	XGMZRFLQBXOCKP-UHFFFAOYSA-N	50374680	CHEMBL429504	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374680	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374680&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454600	160853770		CHEMBL429504				ZINC29127734	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862765	CC(C)(C)CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1	InChI=1S/C29H36N6O3S/c1-28(2,3)17-34-11-7-20(8-12-34)31-25(37)21-15-39-27(32-21)33-24(36)19-6-5-18-13-23-26(38)30-16-29(9-4-10-29)35(23)22(18)14-19/h5-6,13-15,20H,4,7-12,16-17H2,1-3H3,(H,30,38)(H,31,37)(H,32,33,36)	MJQUKUIDCUNAAB-UHFFFAOYSA-N	50374681	CHEMBL257834	MAP kinase-activated protein kinase 2	Homo sapiens		 2							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374681&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24882562	160853771		CHEMBL257834				ZINC29127774	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862766	CC(C)(C)CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC(C)(C)n4c3c2)n1	InChI=1S/C28H36N6O3S/c1-27(2,3)16-33-10-8-19(9-11-33)30-24(36)20-14-38-26(31-20)32-23(35)18-7-6-17-12-22-25(37)29-15-28(4,5)34(22)21(17)13-18/h6-7,12-14,19H,8-11,15-16H2,1-5H3,(H,29,37)(H,30,36)(H,31,32,35)	WWRZEFXYASLXQU-UHFFFAOYSA-N	50374682	CHEMBL403154	MAP kinase-activated protein kinase 2	Homo sapiens		 2							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374682	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374682&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454629	160853772		CHEMBL403154				ZINC29127776	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862767	CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1	InChI=1S/C25H28N6O3S/c1-30-9-5-17(6-10-30)27-22(33)18-13-35-24(28-18)29-21(32)16-4-3-15-11-20-23(34)26-14-25(7-2-8-25)31(20)19(15)12-16/h3-4,11-13,17H,2,5-10,14H2,1H3,(H,26,34)(H,27,33)(H,28,29,32)	GGVFNPFXQLBATK-UHFFFAOYSA-N	50374683	CHEMBL258045	MAP kinase-activated protein kinase 2	Homo sapiens		 2							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374683	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374683&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454631	160853773		CHEMBL258045				ZINC29127778	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862768	CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC(C)(C)n4c3c2)n1	InChI=1S/C24H28N6O3S/c1-24(2)13-25-22(33)19-10-14-4-5-15(11-18(14)30(19)24)20(31)28-23-27-17(12-34-23)21(32)26-16-6-8-29(3)9-7-16/h4-5,10-12,16H,6-9,13H2,1-3H3,(H,25,33)(H,26,32)(H,27,28,31)	XWFUFXHTXQHKMY-UHFFFAOYSA-N	50374684	CHEMBL270148	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374684	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374684&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454652	160853774		CHEMBL270148				ZINC29127811	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862769	CC1(C)CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NC1CCCCC1	InChI=1S/C24H27N5O3S/c1-24(2)13-25-22(32)19-10-14-8-9-15(11-18(14)29(19)24)20(30)28-23-27-17(12-33-23)21(31)26-16-6-4-3-5-7-16/h8-12,16H,3-7,13H2,1-2H3,(H,25,32)(H,26,31)(H,27,28,30)	NCJUTJMETHXIGT-UHFFFAOYSA-N	50374685	CHEMBL270150	MAP kinase-activated protein kinase 2	Homo sapiens		 19							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374685	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374685&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454654	160853775		CHEMBL270150				ZINC29127815	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862770	CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NC1CCN(Cc2ccccc2)CC1	InChI=1S/C29H30N6O3S/c1-18-15-30-28(38)25-13-20-7-8-21(14-24(20)35(18)25)26(36)33-29-32-23(17-39-29)27(37)31-22-9-11-34(12-10-22)16-19-5-3-2-4-6-19/h2-8,13-14,17-18,22H,9-12,15-16H2,1H3,(H,30,38)(H,31,37)(H,32,33,36)	KMABUODWYFGFEI-UHFFFAOYSA-N	50374686	CHEMBL403286	MAP kinase-activated protein kinase 2	Homo sapiens		 9							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374686	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374686&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454653	160853776		CHEMBL403286				ZINC29127814	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862771	CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NC1CCN(CC(C)(C)C)CC1	InChI=1S/C27H34N6O3S/c1-16-13-28-25(36)22-11-17-5-6-18(12-21(17)33(16)22)23(34)31-26-30-20(14-37-26)24(35)29-19-7-9-32(10-8-19)15-27(2,3)4/h5-6,11-12,14,16,19H,7-10,13,15H2,1-4H3,(H,28,36)(H,29,35)(H,30,31,34)	GXDHJMHFSCNYBN-UHFFFAOYSA-N	50374687	CHEMBL256194	MAP kinase-activated protein kinase 2	Homo sapiens		 3							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374687	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374687&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454680	160853777		CHEMBL256194				ZINC29127871	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862772	CC(C)CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC(C)n4c3c2)n1	InChI=1S/C26H32N6O3S/c1-15(2)13-31-8-6-19(7-9-31)28-24(34)20-14-36-26(29-20)30-23(33)18-5-4-17-10-22-25(35)27-12-16(3)32(22)21(17)11-18/h4-5,10-11,14-16,19H,6-9,12-13H2,1-3H3,(H,27,35)(H,28,34)(H,29,30,33)	QLMOSLLPTJWRHG-UHFFFAOYSA-N	50374688	CHEMBL255991	MAP kinase-activated protein kinase 2	Homo sapiens		 4							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374688	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374688&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454679	160853778		CHEMBL255991				ZINC29127869	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862773	CCN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC(C)n4c3c2)n1	InChI=1S/C24H28N6O3S/c1-3-29-8-6-17(7-9-29)26-22(32)18-13-34-24(27-18)28-21(31)16-5-4-15-10-20-23(33)25-12-14(2)30(20)19(15)11-16/h4-5,10-11,13-14,17H,3,6-9,12H2,1-2H3,(H,25,33)(H,26,32)(H,27,28,31)	GITCIQPIHDKHIG-UHFFFAOYSA-N	50374689	CHEMBL256196	MAP kinase-activated protein kinase 2	Homo sapiens		 7							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374689	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374689&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454683	160853779		CHEMBL256196				ZINC29127875	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50862774	CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc(cs1)C(=O)NCC(C)(C)C	InChI=1S/C22H25N5O3S/c1-12-9-23-20(30)17-7-13-5-6-14(8-16(13)27(12)17)18(28)26-21-25-15(10-31-21)19(29)24-11-22(2,3)4/h5-8,10,12H,9,11H2,1-4H3,(H,23,30)(H,24,29)(H,25,26,28)	JGNZTJUQNULPSL-UHFFFAOYSA-N	50374690	CHEMBL271863	MAP kinase-activated protein kinase 2	Homo sapiens		 46							ChEMBL	10.1016/j.bmcl.2007.12.037	10.7270/Q22B8ZWZ	18221871			Goldberg, DR; Choi, Y; Cogan, D; Corson, M; DeLeon, R; Gao, A; Gruenbaum, L; Hao, MH; Joseph, D; Kashem, MA; Miller, C; Moss, N; Netherton, MR; Pargellis, CP; Pelletier, J; Sellati, R; Skow, D; Torcellini, C; Tseng, YC; Wang, J; Wasti, R; Werneburg, B; Wu, JP; Xiong, Z	Boehringer Ingelheim Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374690	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374690&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44454705	160853780		CHEMBL271863				ZINC29127922	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50895792	Cc1ccc(F)c(NC(=O)Nc2ccc(cc2)-c2cccc3[nH]nc(N)c23)c1	InChI=1S/C21H18FN5O/c1-12-5-10-16(22)18(11-12)25-21(28)24-14-8-6-13(7-9-14)15-3-2-4-17-19(15)20(23)27-26-17/h2-11H,1H3,(H3,23,26,27)(H2,24,25,28)	MPVGZUGXCQEXTM-UHFFFAOYSA-N	21079	1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methyl-phenyl)urea::1-[4-(3-amino-1H-indazol-4-yl)phenyl]-3-(2-fluoro-5-methylphenyl)urea::1-[4-(3-azanyl-1H-indazol-4-yl)phenyl]-3-(2-fluoranyl-5-methyl-phenyl)urea::3-[4-(3-amino-1H-indazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea::ABT-869::Aminoindazole, 3::CHEMBL223360::cid_11485656	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21079	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21079&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11485656	49689152		CHEMBL223360		5657		ZINC06718813	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50895793	CC1(C)CNc2cc(NC(=O)c3cccnc3NCc3ccncc3)ccc12	InChI=1S/C22H23N5O/c1-22(2)14-26-19-12-16(5-6-18(19)22)27-21(28)17-4-3-9-24-20(17)25-13-15-7-10-23-11-8-15/h3-12,26H,13-14H2,1-2H3,(H,24,25)(H,27,28)	RAHBGWKEPAQNFF-UHFFFAOYSA-N	24773	AMG 706::AMG-706::Motesanib::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)-3-pyridinecarboxamide::N-(3,3-dimethyl-1,2-dihydroindol-6-yl)-2-(pyridin-4-ylmethylamino)pyridine-3-carboxamide::N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyridin-4-ylmethyl)amino]pyridine-3-carboxamide::N-(3,3-dimethylindolin-6-yl)-2-(4-pyridylmethylamino)nicotinamide::US10464902, Motesanib::cid_11667893	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=24773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=24773&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	706	3EFL	11667893	56269724	51098			5660		ZINC18710082	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50895794	CCN1CCN(Cc2ccc(NC(=O)Nc3ccc(Oc4cc(NC)ncn4)cc3)cc2C(F)(F)F)CC1	InChI=1S/C26H30F3N7O2/c1-3-35-10-12-36(13-11-35)16-18-4-5-20(14-22(18)26(27,28)29)34-25(37)33-19-6-8-21(9-7-19)38-24-15-23(30-2)31-17-32-24/h4-9,14-15,17H,3,10-13,16H2,1-2H3,(H,30,31,32)(H2,33,34,37)	ODPGGGTTYSGTGO-UHFFFAOYSA-N	31085	1-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea::1-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::1-[4-[(4-ethylpiperazino)methyl]-3-(trifluoromethyl)phenyl]-3-[4-[6-(methylamino)pyrimidin-4-yl]oxyphenyl]urea::AST-487::cid_11409972	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31085	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31085&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11409972	252615335				5661		ZINC23247639	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50895795	CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)n[nH]3)ncnc2c1	InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33)	QYZOGCMHVIGURT-UHFFFAOYSA-N	26300	2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}quinazolin-4-yl)amino]-1H-pyrazol-5-yl}-N-(3-fluorophenyl)acetamide::CHEMBL215152::cid_16007391::pyrazoloquinazoline deriv., 34	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26300&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	YJA	4C2V	16007391	56464737		CHEMBL215152		5663		ZINC16697102	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50895796	Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)c2ccccc12)C(C)(C)C	InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)	MVCOAUNKQVWQHZ-UHFFFAOYSA-N	13533	1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(4-methylphenyl)-3-pyrazolyl]-3-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea::1-[5-tert-butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-morpholinoethoxy)-1-naphthyl]urea::3-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-1-[4-(2-morpholin-4-ylethoxy)naphthalen-1-yl]urea::3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea::BIRB 796::BIRB-796::BIRB-796, 3::CHEMBL103667::D3RKN_73::Doramapimod::US11407771, Compound 43::US8933228, BIRB 796::US9187470, 43 (BIRB-796)::US9242960, BIRB 796::US9260410, BIRB796::cid_156422::diaryl urea compound 10	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13533&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B96	4JVG,1KV2,6GTT,5N66,4TWN,3NPC,3FZS	156422	46513934		CHEMBL103667	DB03044	5668		ZINC24044436	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50895797	CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1	InChI=1S/C17H24N4O2S2/c1-17(2,3)12-8-19-13(23-12)10-24-14-9-20-16(25-14)21-15(22)11-4-6-18-7-5-11/h8-9,11,18H,4-7,10H2,1-3H3,(H,20,21,22)	OUSFTKFNBAZUKL-UHFFFAOYSA-N	5931	BMS-387072::CHEMBL296468::N-(5-{[(5-tert-butyl-1,3-oxazol-2-yl)methyl]sulfanyl}-1,3-thiazol-2-yl)piperidine-4-carboxamide::N-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarboxamide::cid_3025986	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5931&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	56H	5D1J	3025986	8035540		CHEMBL296468		5670		ZINC03816409	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50895798	CN1CCN(CC1)c1ccc2nc([nH]c2c1)-c1c(N)c2c(F)cccc2[nH]c1=O	InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11H,7-10H2,1H3,(H,24,25)(H3,23,26,29)	PIQCTGMSNWUMAF-UHFFFAOYSA-N	25118	(3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,3-dihydrobenzimidazol-2-ylidene]carbostyril::4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-1,3-benzodiazol-2-yl]-1,2-dihydroquinolin-2-one::CHEMBL522892::CHIR-258	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25118	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25118&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9886808	56374260		CHEMBL522892		5962		ZINC03816310	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890955	Cn1c(Nc2ccc(cc2)C(F)(F)F)nc2cc(Oc3ccnc(c3)-c3ncc([nH]3)C(F)(F)F)ccc12	InChI=1S/C24H16F6N6O/c1-36-19-7-6-15(10-17(19)34-22(36)33-14-4-2-13(3-5-14)23(25,26)27)37-16-8-9-31-18(11-16)21-32-12-20(35-21)24(28,29)30/h2-12H,1H3,(H,32,35)(H,33,34)	YABJJWZLRMPFSI-UHFFFAOYSA-N	31088	1-methyl-5-[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]pyridin-4-yl]oxy-N-[4-(trifluoromethyl)phenyl]benzimidazol-2-amine::1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridinyl]oxy]-N-[4-(trifluoromethyl)phenyl]-2-benzimidazolamine::CHIR-265::[1-methyl-5-[[2-[5-(trifluoromethyl)-1H-imidazol-2-yl]-4-pyridyl]oxy]benzimidazol-2-yl]-[4-(trifluoromethyl)phenyl]amine::cid_11656518	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31088	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31088&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	55J	5CT7	11656518	252615336				5674		ZINC18710085	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890956	Fc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)c(NC(=O)C=C)cc23)cc1Cl	InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)	OMZCMEYTWSXEPZ-UHFFFAOYSA-N	4779	CHEMBL31965::CHEMBL545315::CI-1033::Canertinib::N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide::PD0183805::US10507209, Compound CI-1033::US9730934, CI-1033::cid_156414	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4779&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			156414	8034429	61399	CHEMBL31965CHEMBL545315	DB05424	5675		ZINC27439698	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890957	C[C@@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N	InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1	UJLAWZDWDVHWOW-YPMHNXCESA-N	50193995	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile::CHEMBL221959::CP-690550::TOFACITINIB CITRATE::Tofacitinib::Tofacitinib citrate (1)::US10112907, Example 00035::US10399979, Compound Tofacitinib::US10766894, Compound TABLE 1.20::US10875847, Compound Tofacitinib::US11078206, Example Tofacitinib::US11203595, TABLE 1.20::US11339167, Example Tofacitinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193995&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MI1	3LXK,3LXN,4OTI,3EYG,3FUP	9926791	104076339	71200	CHEMBL221959	DB08183	5677		ZINC03818808	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890958	COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1	InChI=1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+	LLVZBTWPGQVVLW-SNAWJCMRSA-N	31340	2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]anilino]-6-quinazolinyl]prop-2-enyl]acetamide::2-methoxy-N-[(E)-3-[4-[3-methyl-4-[(6-methyl-3-pyridyl)oxy]anilino]quinazolin-6-yl]allyl]acetamide::2-methoxy-N-[(E)-3-[4-[[3-methyl-4-(6-methylpyridin-3-yl)oxy-phenyl]amino]quinazolin-6-yl]prop-2-enyl]ethanamide::CHEMBL483321::CP-724714::cid_9874913	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31340	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31340&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9874913	252615341		CHEMBL483321				ZINC03817105	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890959	Cc1nc(Nc2ncc(s2)C(=O)Nc2c(C)cccc2Cl)cc(n1)N1CCN(CCO)CC1	InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)	ZBNZXTGUTAYRHI-UHFFFAOYSA-N	13216	BMS-354825::CHEMBL1421::DASATINIB::N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide::N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide::US10294227, Code Dasatinib::cid_3062316::med.21724, Compound Dasatinib	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13216	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13216&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	1N1	5BVW,5OWR,6FNM,6BSD,5I9Y,2ZVA,3OCT,7ERK,3QLG,3SXR,7N9G,4XLI,3OHT,2Y6O,3LFA,4XEY,2GQG,3K54,3G5D,4QMS,5VCV,5H2U	3062316	46513626	49375	CHEMBL1421	DB01254	5678		ZINC21982951	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890960	CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C	InChI=1S/C24H23ClFN5O2/c1-4-33-22-12-20-17(11-21(22)30-23(32)6-5-9-31(2)3)24(15(13-27)14-28-20)29-16-7-8-19(26)18(25)10-16/h5-8,10-12,14H,4,9H2,1-3H3,(H,28,29)(H,30,32)/b6-5+	WVUNYSQLFKLYNI-AATRIKPKSA-N	31090	(E)-N-[4-(3-chloro-4-fluoro-anilino)-3-cyano-7-ethoxy-6-quinolyl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide::(E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide::(E)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-3-cyano-7-ethoxy-quinolin-6-yl]-4-(dimethylamino)but-2-enamide::EKB-569::Pelitinib::cid_6445562	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31090	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31090&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	93J	7AXM,5VCW	6445562	252615337	38927					ZINC00602803	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890961	COCCOc1cc2ncnc(Nc3cccc(c3)C#C)c2cc1OCCOC	InChI=1S/C22H23N3O4/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25)	AAKJLRGGTJKAMG-UHFFFAOYSA-N	5446	CHEMBL553::ERLOTINIB HYDROCHLORIDE::Erlotinib::Erotinib::N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine Monohydrochloride::N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine::OSI-774::Tarceva::US10189853, erlotinib::US10507209, Compound Erlotinib::US11524945, Compound Erlotinib::US9409845, Table 1, Compound 22: erlotinib::US9730934, Erlotinib::WO2022090481, Example erlotinib::cid_176870	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5446&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	AQ4	4HJO,6DWN,1M17	176870	8035065	114785	CHEMBL553	DB00530	4920		ZINC01546066	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890962	CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl	InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1	BIIVYFLTOXDAOV-YVEFUNNKSA-N	5655	2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]-4H-chromen-4-one::CHEMBL428690::Flavopiridol::US10294218, Example Flavopiridol::US9617225, Flavopiridol	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5655	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5655&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	CPB	1C8K,1E1Y,3BLR,3EBP,4O71	5287969	8035270		CHEMBL428690	DB03496	5680		ZINC21288966	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890963	COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1	InChI=1S/C22H24ClFN4O3/c1-29-20-13-19-16(12-21(20)31-8-2-5-28-6-9-30-10-7-28)22(26-14-25-19)27-15-3-4-18(24)17(23)11-15/h3-4,11-14H,2,5-10H2,1H3,(H,25,26,27)	XGALLCVXEZPNRQ-UHFFFAOYSA-N	5447	CHEMBL939::GEFITINIB::Iressa::N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine::N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine::US10106508, Gefitinib::US10507209, Compound Gefitinib::US9416123, Gefitinib::US9730934, Gefitinib::US9783524, Gefitinib::WO2022090481, Example gefitinib::ZD1839::cid_123631	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5447&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search		2ITO,2ITY,2ITZ	123631	8035066	49668	CHEMBL939	DB00317	4941		ZINC19632614	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890964	COc1ccc(COc2ccc(Cc3cnc(N)nc3N)cc2OC)cc1	InChI=1S/C20H22N4O3/c1-25-16-6-3-13(4-7-16)12-27-17-8-5-14(10-18(17)26-2)9-15-11-23-20(22)24-19(15)21/h3-8,10-11H,9,12H2,1-2H3,(H4,21,22,23,24)	MYQAUKPBNJWPIE-UHFFFAOYSA-N	32362	5-[[3-methoxy-4-[(4-methoxyphenyl)methoxy]phenyl]methyl]pyrimidine-2,4-diamine::GW-2580::[2-amino-5-(3-methoxy-4-p-anisyloxy-benzyl)pyrimidin-4-yl]amine::cid_11617559	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=32362	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=32362&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MUJ	4AT5	11617559	252615797				5685		ZINC13985942	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890965	CN(c1ccc2c(C)n(C)nc2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1	InChI=1S/C21H23N7O2S/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25)	CUIHSIWYWATEQL-UHFFFAOYSA-N	26474	5-({4-[(2,3-dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzene-1-sulfonamide::GW-786034::JMC514632 Compound 13::Pazopanib::cid_10113978	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=26474&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10113978	56464911	71219		DB06589	5698		ZINC11617039	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890966	CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)CC1	InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)	KTUFNOKKBVMGRW-UHFFFAOYSA-N	13530	4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide::CHEMBL941::Gleevec::Imatinib::Imatinib, 21::N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide::STI-571::STI571::US10906896, Cpd imatinib::US11649218, Example Imatinib::US9255107, Imatinib::cid_5291::imatinib-CD3::med.21724, Compound 6	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13530	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13530&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	STI	6HD6,6HD4,2HYY,4BKJ,2PL0,3GVU,6NPU,6NPV,6NPE,4CSV,3MS9,3MSS,4R7I,7N9G,2OIQ,1IEP,1XBB,3HEC,1T46,3FW1,3PYY,6VXH,6JOL,3K5V,5MQT,3OEZ,6KTN,1OPJ	5291	46513933	45783	CHEMBL941	DB00619	5687		ZINC19632618	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890967	Nc1nc(Nc2ccc(cc2)S(N)(=O)=O)nn1C(=O)c1c(F)cccc1F	InChI=1S/C15H12F2N6O3S/c16-10-2-1-3-11(17)12(10)13(24)23-14(18)21-15(22-23)20-8-4-6-9(7-5-8)27(19,25)26/h1-7H,(H2,19,25,26)(H3,18,20,21,22)	KDKUVYLMPJIGKA-UHFFFAOYSA-N	6866	1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b::4-({5-amino-1-[(2,6-difluorophenyl)carbonyl]-1H-1,2,4-triazol-3-yl}amino)benzene-1-sulfonamide::4-[[5-Amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino]-benzenesulfonamide::CHEMBL191003::JNJ-7706621::cid_5330790	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=6866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=6866&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	SKE	5WIN,5USZ,5USY,5DR9,8B99,5OBR,6DRW,5DPV,5DR6,6P11,6P10,3AMA,4QMU,5DT0	5330790	8036422		CHEMBL191003				ZINC03938688	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890968	CS(=O)(=O)CCNCc1ccc(o1)-c1ccc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2c1	InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)	BCFGMOOMADDAQU-UHFFFAOYSA-N	5445	CHEMBL554::GW572016::LAPATINIB DITOSYLATE::Lapatinib::N-{3-chloro-4-[(3-fluoro-benzyl)oxy]phenyl}-6-[5-({2-(methylsulfonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine::N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(5-{[(2-methanesulfonylethyl)amino]methyl}furan-2-yl)quinazolin-4-amine::Tykerb::US10507209, Compound Lapatinib::US10822334, Compound Lapatinib::US9730934, Lapatinib ditosylate::cid_208908	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=5445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=5445&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	FMM	1XKK,3BBT	208908	8035064	49603	CHEMBL554	DB01259	5692		ZINC01550477	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890969	CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21	InChI=1S/C28H28N4O3/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34)/t18-/m0/s1	ZCBUQCWBWNUWSU-SFHVURJKSA-N	17055	(18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^{7,14}.0^{2,6}.0^{8,13}.0^{22,27}]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione::(9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-di(metheno)dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione::K00587a::LY 333531::LY-333531::LY333531::Ruboxistaurin::cid_153999	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17055	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=17055&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	LY4	2J2I,1UU3	153999	46517285				5263		ZINC03812168	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890970	COc1cc2c(ncnc2cc1OCCCN1CCCCC1)N1CCN(CC1)C(=O)Nc1ccc(OC(C)C)cc1	InChI=1S/C31H42N6O4/c1-23(2)41-25-10-8-24(9-11-25)34-31(38)37-17-15-36(16-18-37)30-26-20-28(39-3)29(21-27(26)32-22-33-30)40-19-7-14-35-12-5-4-6-13-35/h8-11,20-23H,4-7,12-19H2,1-3H3,(H,34,38)	UXXQOJXBIDBUAC-UHFFFAOYSA-N	13535	4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-(4-propan-2-yloxyphenyl)piperazine-1-carboxamide::4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin-4-yl]-N-[4-(1-methylethoxy)phenyl]piperazine-1-carboxamide::4-[6-methoxy-7-[3-(1-piperidinyl)propoxy]-4-quinazolinyl]-N-(4-propan-2-yloxyphenyl)-1-piperazinecarboxamide::4-{6-methoxy-7-[3-(piperidin-1-yl)propoxy]quinazolin-4-yl}-N-[4-(propan-2-yloxy)phenyl]piperazine-1-carboxamide::CHEMBL124660::MLN-518::MLN518::N-(4-isopropoxyphenyl)-4-[6-methoxy-7-(3-piperidinopropoxy)quinazolin-4-yl]piperazine-1-carboxamide::cid_3038522	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13535	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13535&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			3038522	46513936		CHEMBL124660	DB05465			ZINC03966243	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890971	OC(=O)c1ccc(Nc2ncc3CN=C(c4cc(Cl)ccc4-c3n2)c2c(F)cccc2F)cc1	InChI=1S/C25H15ClF2N4O2/c26-15-6-9-17-18(10-15)23(21-19(27)2-1-3-20(21)28)29-11-14-12-30-25(32-22(14)17)31-16-7-4-13(5-8-16)24(33)34/h1-10,12H,11H2,(H,33,34)(H,30,31,32)	HHFBDROWDBDFBR-UHFFFAOYSA-N	31093	4-[[7-[2,6-bis(fluoranyl)phenyl]-9-chloranyl-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid::4-[[9-chloro-7-(2,6-difluorophenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]benzoic acid::BDBM31832::CHEMBL259084::MLN-8054::cid_11712649	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31093	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31093&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	ZZL	2X81,5IA1,2WTW,2WTV	11712649	252615338		CHEMBL259084		5696		ZINC18825334	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890972	Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1	InChI=1S/C19H16N4O3/c24-13-4-1-3-12(11-13)17-21-15-14-5-2-6-20-19(14)26-16(15)18(22-17)23-7-9-25-10-8-23/h1-6,11,24H,7-10H2	TUVCWJQQGGETHL-UHFFFAOYSA-N	25045	3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol::3-(4-morpholin-4-ylpyrido[3 ,2 :4,5]furo[3,2-d]pyrimidin-2-yl)phenol::3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-yl)phenol::3-[4-(4-morpholinyl)-2-pyrido[2,3]furo[2,4-b]pyrimidinyl]phenol::3-[6-(morpholin-4-yl)-8-oxa-3,5,10-triazatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-4-yl]phenol::CHEMBL538346::PI-103::US9637488, PI-103::cid_9884685::mTOR Inhibitor, PI103::pyridofuropyrimidine derivative, 2	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=25045	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=25045&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	X6K	2X6K,4L23,4JT6	9884685	56374189		CHEMBL538346		5701		ZINC03963016	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890974	Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1	InChI=1S/C20H15ClN4/c21-15-5-7-16(8-6-15)23-20-18-4-2-1-3-17(18)19(24-25-20)13-14-9-11-22-12-10-14/h1-12H,13H2,(H,23,25)	YCOYDOIWSSHVCK-UHFFFAOYSA-N	4851	(4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine::(A) PTK787::CGP 79787::CHEMBL101253::CHEMBL75232::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-1-phthalazinamine::N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine::PTK-787::PTK787::ZK222584::cid_151194	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4851&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			151194	8034494		CHEMBL75232CHEMBL101253	DB04879	6052		ZINC00007460	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890975	CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1	InChI=1S/C19H26N6O/c1-4-15(11-26)22-19-23-17(20-10-14-8-6-5-7-9-14)16-18(24-19)25(12-21-16)13(2)3/h5-9,12-13,15,26H,4,10-11H2,1-3H3,(H2,20,22,23,24)/t15-/m1/s1	BTIHMVBBUGXLCJ-OAHLLOKOSA-N	7533	(2R)-2-[[6-(benzylamino)-9-isopropyl-purin-2-yl]amino]butan-1-ol::(2R)-2-[[6-(benzylamino)-9-propan-2-ylpurin-2-yl]amino]butan-1-ol::(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-2-purinyl]amino]-1-butanol::(2R)-2-[[6-[(phenylmethyl)amino]-9-propan-2-yl-purin-2-yl]amino]butan-1-ol::(2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-2-yl]amino}butan-1-ol::(R)-Roscovitine::2,6,9-Trisubstituted purine deriv. 28::CHEMBL14762::CYC-202::Roscovitine::cid_160355	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7533	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=7533&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	RRC	3DDQ,1YGK,2A4L,1UNL	160355	11108321		CHEMBL14762		6035		ZINC01649340	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890976	Oc1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)	QHKYPYXTTXKZST-UHFFFAOYSA-N	13531	4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole::4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol::4-[4-(4-fluorophenyl)-5-(4-pyridyl)-4-imidazolin-2-ylidene]cyclohexa-2,5-dien-1-one::4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol::SB-202190::SB202190::biotinylated SB202190	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13531	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13531&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			5353940	172097219						ZINC14951176	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890977	CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1	InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)	CDMGBJANTYXAIV-UHFFFAOYSA-N	13336	4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13336&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search		1A9U,1PME,2EWA	176155	46513744		CHEMBL10		5269		ZINC96006137	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890978	NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc2OCOc2c1)-c1ccccn1	InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)	FHYUGAJXYORMHI-UHFFFAOYSA-N	50110208	4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide::4-(4-Benzo[1,3]dioxol-5-yl-5-pyridin-2-yl-1H-imidazol-2-yl)-benzamide::4-(5-(benzo[d][1,3]dioxol-5-yl)-4-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide::4-(5-benzo[1,3]dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)-benzamide::CHEMBL440084::SB-431542::cid_4521392	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50110208	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50110208&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	085	3TZM	4521392	104005054		CHEMBL440084				ZINC00603769	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890979	CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2)ccn1	InChI=1S/C21H16ClF3N4O3/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25/h2-11H,1H3,(H,26,30)(H2,28,29,31)	MLDQJTXFUGDVEO-UHFFFAOYSA-N	16673	4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide::4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-picolinamide;tosylic acid::BAY 43-9006::BAY 439006::BAY439006::CHEMBL1336::Hit compound, 8::Nexavar::Sorafenib::Sorafenib, 4::US10183928, Sorafenib::US10202365, Compound Sorafenib::US10227329, Compound Sorafenib::US10584114, Compound Sorafenib::US10774070, Compound Sorafenib::US10980809, Example Sorafenib::US11279688, Compound Sorafenib::US11505527, Compound Sorafenib::US9029401, Sorafenib::US9469639, Sorafenib::US9902709, Comparative example 1::Xarelto::cid_216239	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=16673	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=16673&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	BAX	3GCS,4ASD,3WZE,5HI2,3HEG,1UWH,1UWJ,3RGF	216239	46516901	50924	CHEMBL1336	DB00398	5711		ZINC01493878	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890981	Cc1[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c(C)c1C(=O)NC[C@H](O)CN1CCOCC1	InChI=1S/C23H27FN4O4/c1-13-20(10-18-17-9-15(24)3-4-19(17)27-22(18)30)26-14(2)21(13)23(31)25-11-16(29)12-28-5-7-32-8-6-28/h3-4,9-10,16,26,29H,5-8,11-12H2,1-2H3,(H,25,31)(H,27,30)/b18-10-/t16-/m0/s1	CTNPALGJUAXMMC-PMFHANACSA-N	31095	5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-ylidene)methyl]-2,4-dimethyl-N-[(2S)-3-morpholin-4-yl-2-oxidanyl-propyl]-1H-pyrrole-3-carboxamide::5-[(Z)-(5-fluoro-2-keto-indolin-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholino-propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-(4-morpholinyl)propyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-N-[(2S)-2-hydroxy-3-morpholin-4-ylpropyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU-14813::cid_10138259	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=31095	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=31095&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10138259	252615339						ZINC18825344	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890982	CCN(CC)CCNC(=O)c1c(C)[nH]c(\C=C2/C(=O)Nc3ccc(F)cc23)c1C	InChI=1S/C22H27FN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-	WINHZLLDWRZWRT-ATVHPVEESA-N	4814	CHEMBL535::N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide::N-[2-(diethylamino)ethyl]-5-{[(3Z)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-ylidene]methyl}-2,4-dimethyl-1H-pyrrole-3-carboxamide::SU11248::SUNITINIB::SUNITINIB MALATE::US10464902, Sunitinib::US9163010, Sunitinib::US9914707, SU11248	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=4814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=4814&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B49	6NG0,4KS8,3G0F,3G0E,2Y7J,6JOK,6M11,3MIY,3TI1,4QMZ,6V0X,6NFZ,6NFY,4AGD	5329102	8034462	38940	CHEMBL535	DB01268	5713		ZINC03964325	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890983	CN1CCN(CC1)c1cc(Nc2cc(C)n[nH]2)nc(Sc2ccc(NC(=O)C3CC3)cc2)n1	InChI=1S/C23H28N8OS/c1-15-13-20(29-28-15)25-19-14-21(31-11-9-30(2)10-12-31)27-23(26-19)33-18-7-5-17(6-8-18)24-22(32)16-3-4-16/h5-8,13-14,16H,3-4,9-12H2,1-2H3,(H,24,32)(H2,25,26,27,28,29)	GCIKSSRWRFVXBI-UHFFFAOYSA-N	13534	CHEMBL572878::N-[4-({4-[(3-methyl-1H-pyrazol-5-yl)amino]-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl}sulfanyl)phenyl]cyclopropanecarboxamide::N-[4-[[4-(4-methylpiperazino)-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-2-yl]thio]phenyl]cyclopropanecarboxamide::VX-680::VX680::cyclopropane carboxylic acid {4-[4-(4-methyl-piperazin-1-yl)-6-(5-methyl-2H-pyrazol-3-ylamino)-pyrimidin-2ylsulphanyl]-phenyl}-amide	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=13534	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=13534&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	VX6	2F4J,6GR9,6BRJ,3E5A,4ZOG,4B8M,5WNM,3AMB,4JBQ,4AF3,2XYN	5494449	46513935		CHEMBL572878		5718		ZINC03820040	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890984	Fc1ccc(Sc2ccc3c(-c4c(Cl)cccc4Cl)c(=O)ncn3n2)c(F)c1	InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H	VEPKQEUBKLEPRA-UHFFFAOYSA-N	15244	5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-a]pyridazin-6-one::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6-pyrimido[1,6-b]pyridazinone::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]pyrimido[1,6-b]pyridazin-6-one::5-(2,6-dichlorophenyl)-9-(2,4-difluorophenyl)sulfanyl-1,3,10-triazabicyclo[4.4.0]deca-2,5,7,9-tetraen-4-one::5-[2,6-bis(chloranyl)phenyl]-2-[2,4-bis(fluoranyl)phenyl]sulfanyl-pyrimido[1,6-b]pyridazin-6-one::VX-745::VX745::cid_3038525	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15244&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	52P	3ZSI,3HP5,3FC1	3038525	46515551			DB07138			ZINC13493055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50890985	COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C)CC1	InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)	UHTHHESEBZOYNR-UHFFFAOYSA-N	21	CHEMBL24828::N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine::VANDETANIB::ZD-6474::ZD6474::cid_3081361	MAP kinase-activated protein kinase 2	Homo sapiens			>10000						ChEMBL	10.1038/nbt1358	10.7270/Q2TT4RX2	18183025			Karaman, MW; Herrgard, S; Treiber, DK; Gallant, P; Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Hunt, JP; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Wodicka, LM; Zarrinkar, PP	Ambit Biosciences	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=21	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=21&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	ZD6	2IVU	3081361	8030012	49960	CHEMBL24828	DB08764			ZINC03834198	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50879721	C[C@@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N	InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1	UJLAWZDWDVHWOW-YPMHNXCESA-N	50193995	3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-(4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile::3-{(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl}-3-oxopropanenitrile::CHEMBL221959::CP-690550::TOFACITINIB CITRATE::Tofacitinib::Tofacitinib citrate (1)::US10112907, Example 00035::US10399979, Compound Tofacitinib::US10766894, Compound TABLE 1.20::US10875847, Compound Tofacitinib::US11078206, Example Tofacitinib::US11203595, TABLE 1.20::US11339167, Example Tofacitinib	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1126/science.1087061	10.7270/Q22Z16FK	14593182			Changelian, PS; Flanagan, ME; Ball, DJ; Kent, CR; Magnuson, KS; Martin, WH; Rizzuti, BJ; Sawyer, PS; Perry, BD; Brissette, WH; McCurdy, SP; Kudlacz, EM; Conklyn, MJ; Elliott, EA; Koslov, ER; Fisher, MB; Strelevitz, TJ; Yoon, K; Whipple, DA; Sun, J; Munchhof, MJ; Doty, JL; Casavant, JM; Blumenkopf, TA; Hines, M; Brown, MF; Lillie, BM; Subramanyam, C; Shang-Poa, C; Milici, AJ; Beckius, GE; Moyer, JD; Su, C; Woodworth, TG; Gaweco, AS; Beals, CR; Littman, BH; Fisher, DA; Smith, JF; Zagouras, P; Magna, HA; Saltarelli, MJ; Johnson, KS; Nelms, LF; Des Etages, SG; Hayes, LS; Kawabata, TT; Finco-Kent, D; Baker, DL; Larson, M; Si, MS; Paniagua, R; Higgins, J; Holm, B; Reitz, B; Zhou, YJ; Morris, RE; O'Shea, JJ; Borie, DC	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50193995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50193995&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	MI1	3LXK,3LXN,4OTI,3EYG,3FUP	9926791	104076339	71200	CHEMBL221959	DB08183	5677		ZINC03818808	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50908008	CC(C)CC(=O)Nc1[nH]nc2c1CN(C(=O)C1CCN(C)CC1)C2(C)C	InChI=1S/C19H31N5O2/c1-12(2)10-15(25)20-17-14-11-24(19(3,4)16(14)21-22-17)18(26)13-6-8-23(5)9-7-13/h12-13H,6-11H2,1-5H3,(H2,20,21,22,25)	HUXYBQXJVXOMKX-UHFFFAOYSA-N	50378657	CHEMBL1230607	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2010.01.042	10.7270/Q21R6RG5	20153204			Brasca, MG; Albanese, C; Alzani, R; Amici, R; Avanzi, N; Ballinari, D; Bischoff, J; Borghi, D; Casale, E; Croci, V; Fiorentini, F; Isacchi, A; Mercurio, C; Nesi, M; Orsini, P; Pastori, W; Pesenti, E; Pevarello, P; Roussel, P; Varasi, M; Volpi, D; Vulpetti, A; Ciomei, M	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378657	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378657&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46191454	160857740		CHEMBL1230607				ZINC52509437	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50908043	CC(C)(C)C(=O)N1Cc2c(NC(=O)c3cc(F)cc(F)c3)[nH]nc2C1(C)C	InChI=1S/C19H22F2N4O2/c1-18(2,3)17(27)25-9-13-14(19(25,4)5)23-24-15(13)22-16(26)10-6-11(20)8-12(21)7-10/h6-8H,9H2,1-5H3,(H2,22,23,24,26)	QXBKFUBBGBWPCJ-UHFFFAOYSA-N	50307987	CHEMBL604712::N-[5-(2,2-Dimethylpropanoyl)-6,6-dimethyl-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl]-3,5-difluorobenzamide	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2010.01.042	10.7270/Q21R6RG5	20153204			Brasca, MG; Albanese, C; Alzani, R; Amici, R; Avanzi, N; Ballinari, D; Bischoff, J; Borghi, D; Casale, E; Croci, V; Fiorentini, F; Isacchi, A; Mercurio, C; Nesi, M; Orsini, P; Pastori, W; Pesenti, E; Pevarello, P; Roussel, P; Varasi, M; Volpi, D; Vulpetti, A; Ciomei, M	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50307987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50307987&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10429593	104162348		CHEMBL604712				ZINC38827189	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50907143	Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O	InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	ZKHQWZAMYRWXGA-KQYNXXCUSA-N	50366480	ADENOSINE TRIPHOSPHATE::ATP	MAP kinase-activated protein kinase 2	Homo sapiens		 2800							ChEMBL	10.1016/j.bmcl.2009.10.102	10.7270/Q24M95GT	19919896			Argiriadi, MA; Ericsson, AM; Harris, CM; Banach, DL; Borhani, DW; Calderwood, DJ; Demers, MD; Dimauro, J; Dixon, RW; Hardman, J; Kwak, S; Li, B; Mankovich, JA; Marcotte, D; Mullen, KD; Ni, B; Pietras, M; Sadhukhan, R; Sousa, S; Tomlinson, MJ; Wang, L; Xiang, T; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	ATP	7UT9,1Y64,7LNU,7LN3,7LN2,7LN1,7LN0,7LN6,7LN5,7LN4,1NGE,1NGF,1NGG,1NGH,3LTA,3LTC,2NPI,2ZDQ,7NHL,1GY3,6J18,6J17,1G3I,7SGL,2BU2,2Q7G,2BUP,3H8V,6GFA,7QI6,7QI4,1H8H,4AUI,1FMW,1XDP,7ZSE,3O8L,5HNV,7ABR,3EHG,1KAZ,1KAY,1KAX,7R31,7U6Y,6TAY,6TAX,6DDZ,1XMI,1XMJ,6E0O,4A8M,4A8F,4A8Y,4A8Q,4A8S,4A8W,7JIJ,7CRC,7EKL,8H99,7N30,7N31,6YWX,6YWY,6YWE,6YW6,6YW7,6YW5,4B2Q,2W5G,2W5I,3HBT,8DAR,3CQD,4QC2,1Q97,4GY2,6FU2,1E4G,3FFK,3JZM,4CI6,1MO8,4QNR,6D3S,6D3R,7P2E,7P2Y,7V2Z,5ECQ,5ECP,4XWO,4XW5,2VHT,2VHQ,6NHX,6NHZ,6KCL,6KCM,6KC0,7JM6,7JM7,6MT9,1U5R,1I7L,1OL6,6JRS,7D4O,7D4U,7T3U,1ZAO,1Q24,6ZQM,3A5N,1PJ4,7AI5,3TPQ,7C1Z,4Q4Z,1B0U,7OQH,7LJ1,6P8J,3DGO,6ZO4,5FV0,6L59,6L57,4X6R,3R1R,7PX9,7U9X,7WTD,7WTE,7U9T,7U9K,2BBT,2BBS,2BBO,6ZTQ,4O0M,6GFH,1JKN,7NGF,7MJP,7MJQ,7MJO,1UF9,5AFU,7KSM,6UDQ,6RKE,6RKD,6RKA,7VVY,7VVZ,1KVK,4H4K,7OZ1,2OLQ,2OLR,7UUX,1NMD,1NM1,3Q60,7OIK,3BG5,3E1Y,7CGN,4GP7,1RDQ,2Q97,6ZYW,6ZYY,7W79,4DX2,3WVL,1SVM,3WV9,4DXL,6Z3R,6IUB,6IUC,5N9X,1HLU,7VLR,3JAY,6QRI,6QDV,3V2U,7AT1,7L1R,7L1S,7L1Q,6S47,6N30,7AM2,6OA9,7YFP,7YFN,7S61,7S67,7Y38,7RFH,7RFE,7RFG,6O75,6O78,1P8Z,6PTN,6PTO,7WPM,5FL7,3QUO,3QUN,4AZW,6YAR,6YAY,1G21,7EV2,7EV3,7M74,2BTF,3REP,3REU,8FHN,8FHO,7AIR,7AIQ,7AIP,3W1G,4TL7,1HCK,6HZM,7DC8,7RNR,4WTV,1AQ2,6N2Y,1NSF,1NSY,2CG9,7JGR,7JGA,5CYR,1YXQ,7FDV,7WAJ,6AB0,6AB2,6AB8,6ABK,3H5N,6YT3,6W18,6W17,6W1Z,7NZ0,7NZ3,1UEV,3T0Z,2F43,2QUI,7ZH9,8BI0,1E79,5U03,4TQD,7PO3,7RES,6CMW,2Z1U,7UJP,7UJT,7P3F,7P3N,4WAE,1TFW,1A0I,1DEJ,4M3Y,4XVU,6NOO,6NOP,6NO7,3UMP,3UMO,5J1T,8ESC,4EAJ,4EAK,4EAH,4EAG,7RAV,3G6V,6KSH,8E9B,1R9T,7MD2,6AEC,3NCQ,3MN6,3MN7,3MN5,3MN9,3UQE,3UQD,5WC0,6SYT,5WCB,4H0T,4H0V,4H0X,4H0Y,4H03,1PK8,7WYX,2FSG,7BT2,7WPT,7WPX,7WPN,7WPL,8DAV,3EQB,8CVT,4KH0,2PAV,2PAA,5EOU,5OTR,2O0H,6PAO,6PAN,6PAQ,5XVU,5FWP,5FWK,5FWL,5FWM,7CM9,7K3Z,4UP9,1TID,7Z5J,1RFQ,6ZSP,5JRJ,5LVP,5D15,6GRG,7MI6,7MI3,3SJH,2AQX,4Z94,6RJ4,3TLX,4O4F,4O4E,4O4D,7W1Y,4AN3,4KGM,4KGV,2PZE,2PZF,2PZG,3Q53,3LKI,3LKK,6PZ9,4XHO,6PZA,6PZI,7NK7,7CFI,3QO3,3QO7,7NZM,7EER,5YA1,6JD4,6JD5,5IE2,6ZXF,6ZXG,6ZXH,8DAS,8DAT,1SU2,3WQU,7QBA,5DRD,5DR2,7QO6,2R9V,4FO0,7V00,6N2Z,4FWM,1Y8R,1Y8P,1Y8Q,7KO2,7LHT,7LHW,1NYR,6BHU,6TQE,4M3T,4M3U,4M3W,4M3R,4M3X,4M3Z,2P55,1IJJ,5YZG,6JIU,6JIY,6JII,6JI0,6ZM6,6ZM5,5O5W,1F9A,8AAZ,4DLK,7QO5,7QO4,7B93,7M6L,7PW7,7M6A,7DYI,7DYE,7K2T,3C9R,1MDU,1KO5,3PGK,4AT8,4AT1,1XKV,8G8F,5XMI,5XMK,1Z0S,7VX8,7N1P,1RYR,1RYS,4FF3,6W23,6W22,6W21,6W20,6W24,4FFR,5VQA,4BJR,8DGC,4F93,6X2N,5ZTB,7R8E,7XA9,3FDX,1MIW,2Z08,2Z02,6CN2,7UIR,7P48,4KR7,3PJR,7PJI,2HMP,2HMU,2HMW,5EXY,4U07,4U0M,1WUA,7SHM,5ECK,5ECI,5ECH,5ECN,7Q6I,5LIL,7Q6F,7Q6D,3ULE,4KB6,7RGQ,6VOM,6VOL,6VOO,6VON,6VOI,6VOH,6VOK,6VOJ,6VOG,6VOF,3DKC,2GNK,3MMV,7LJF,2WPD,5V2L,5XZ9,1PHK,6O1V,7VAL,8A5P,8A5Q,1QZ5,1QZ6,3EPS,5LUH,4XBR,7PUP,7PUB,1YP3,6MAT,5X9G,5X9H,7P3W,8EOP,1LHR,1RGI,6ZR2,7WIT,3A7H,1L2T,6VTD,6VTB,7TVE,5I9E,4DQW,3CI1,3CI5,3CI4,3CIP,3CIS,6AH5,6AH4,2A84,7RZY,6RIS,6RIQ,4ZS4,2IA6,2IAJ,3ZS7,3LL3,4M9Z,4M9X,4M9Y,4M9S,7T0V,5LVO,8BX8,1MB9,2YXU,3QNO,3AB8,7ESB,2Y27,6JCU,2C01,7TCH,2C96,6Z1P,6R4S,7KL1,1ZYD,7PLJ,3M9O,4RTF,2XCW,3V01,3V04,2R86,2ILY,1N48,7W3M,7W3B,7LI3,7LI4,3Q9L,1R8B,5DK4,7U2X,2X15,5I4N,4P33,5YUD,6JH6,6JH8,6JH9,6U0M,8DGF,6IFR,2FGH,3W3D,7RL0,1ASZ,6CTA,3IQ0,4WH3,5GQL,5GQJ,8BD6,8BD4,8BD5,6TE0,4V02,4V0U,3GQK,1FQ1,6HBU,3QX9,3QXC,1U9I,5CSH,4TU0,2W00,2W02,3U8X,4ZGN,7NXV,2FF3,7K58,5T0G,5T0C,5T0J,5T0I,4GT3,7K5B,6FZB,4RQV,5ZUA,5U2H,7WIW,6RDW,7OIM,5A9P,1B8A,5A99,5A98,3X2W,3X2V,3X2U,6COM,7P5Z,7P52,7P50,2PNN,4XTR,4U1R,7ZZ3,7ZZ4,4A6X,4CBX,4CBU,4CBW,4CB0,3UC5,8FZQ,7D7Y,2RSF,6P8V,5KOY,6P80,3FPB,6EMA,2EWW,4G5Y,7ORJ,7ORK,7ORN,1B38,1B39,5Z68,5Z6R,7SXO,2PC9,7UO7,7PVN,1V1B,5L9N,3KE5,3KEU,4FXF,7NJL,7NJO,7NJN,7NJK,7NJQ,7NJS,6ZQN,5XJC,3DGL,2QKM,2QK4,2GBL,3SL2,6FML,7KZU,7KZI,5ACK,3CHW,5MWL,5MW8,5H67,5GJC,8BWY,3M3N,4HUT,7RCK,2ZHZ,7PSA,6WA8,6OIF,2OOY,4M63,7LG5,7LGQ,7LGM,6TDU,6TDY,3LMI,7JPS,7JPR,7JPQ,7JPP,7JPO,7JPN,6AWH,6AWG,4JYZ,5LXQ,6YII,6MM2,4CT2,4CT1,7T65,4CTA,6JBJ,6JBK,6JBD,3QB0,7Z3O,4IFE,3J2T,6IP2,7N74,5SVK,2A42,2A41,2A40,5OBJ,5NBN,5NBM,5NBL,1AYL,7VX0,7N6I,1KXP,1N5I,1N56,6N0T,7LJL,1V3S,7U1E,7U1S,7U1Q,2X0Q,3U9D,6AZ0,5CE3,1TQP,8APF,6JWY,6JWQ,6JWS,6JWT,6JWW,6JWV,5D4C,2XSZ,6U1D,6U1E,6U1F	5957	160845582	15422				C03517		1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50907144	Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O	InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	ZKHQWZAMYRWXGA-KQYNXXCUSA-N	50366480	ADENOSINE TRIPHOSPHATE::ATP	MAP kinase-activated protein kinase 2	Homo sapiens		 6300							ChEMBL	10.1016/j.bmcl.2009.10.102	10.7270/Q24M95GT	19919896			Argiriadi, MA; Ericsson, AM; Harris, CM; Banach, DL; Borhani, DW; Calderwood, DJ; Demers, MD; Dimauro, J; Dixon, RW; Hardman, J; Kwak, S; Li, B; Mankovich, JA; Marcotte, D; Mullen, KD; Ni, B; Pietras, M; Sadhukhan, R; Sousa, S; Tomlinson, MJ; Wang, L; Xiang, T; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	ATP	7UT9,1Y64,7LNU,7LN3,7LN2,7LN1,7LN0,7LN6,7LN5,7LN4,1NGE,1NGF,1NGG,1NGH,3LTA,3LTC,2NPI,2ZDQ,7NHL,1GY3,6J18,6J17,1G3I,7SGL,2BU2,2Q7G,2BUP,3H8V,6GFA,7QI6,7QI4,1H8H,4AUI,1FMW,1XDP,7ZSE,3O8L,5HNV,7ABR,3EHG,1KAZ,1KAY,1KAX,7R31,7U6Y,6TAY,6TAX,6DDZ,1XMI,1XMJ,6E0O,4A8M,4A8F,4A8Y,4A8Q,4A8S,4A8W,7JIJ,7CRC,7EKL,8H99,7N30,7N31,6YWX,6YWY,6YWE,6YW6,6YW7,6YW5,4B2Q,2W5G,2W5I,3HBT,8DAR,3CQD,4QC2,1Q97,4GY2,6FU2,1E4G,3FFK,3JZM,4CI6,1MO8,4QNR,6D3S,6D3R,7P2E,7P2Y,7V2Z,5ECQ,5ECP,4XWO,4XW5,2VHT,2VHQ,6NHX,6NHZ,6KCL,6KCM,6KC0,7JM6,7JM7,6MT9,1U5R,1I7L,1OL6,6JRS,7D4O,7D4U,7T3U,1ZAO,1Q24,6ZQM,3A5N,1PJ4,7AI5,3TPQ,7C1Z,4Q4Z,1B0U,7OQH,7LJ1,6P8J,3DGO,6ZO4,5FV0,6L59,6L57,4X6R,3R1R,7PX9,7U9X,7WTD,7WTE,7U9T,7U9K,2BBT,2BBS,2BBO,6ZTQ,4O0M,6GFH,1JKN,7NGF,7MJP,7MJQ,7MJO,1UF9,5AFU,7KSM,6UDQ,6RKE,6RKD,6RKA,7VVY,7VVZ,1KVK,4H4K,7OZ1,2OLQ,2OLR,7UUX,1NMD,1NM1,3Q60,7OIK,3BG5,3E1Y,7CGN,4GP7,1RDQ,2Q97,6ZYW,6ZYY,7W79,4DX2,3WVL,1SVM,3WV9,4DXL,6Z3R,6IUB,6IUC,5N9X,1HLU,7VLR,3JAY,6QRI,6QDV,3V2U,7AT1,7L1R,7L1S,7L1Q,6S47,6N30,7AM2,6OA9,7YFP,7YFN,7S61,7S67,7Y38,7RFH,7RFE,7RFG,6O75,6O78,1P8Z,6PTN,6PTO,7WPM,5FL7,3QUO,3QUN,4AZW,6YAR,6YAY,1G21,7EV2,7EV3,7M74,2BTF,3REP,3REU,8FHN,8FHO,7AIR,7AIQ,7AIP,3W1G,4TL7,1HCK,6HZM,7DC8,7RNR,4WTV,1AQ2,6N2Y,1NSF,1NSY,2CG9,7JGR,7JGA,5CYR,1YXQ,7FDV,7WAJ,6AB0,6AB2,6AB8,6ABK,3H5N,6YT3,6W18,6W17,6W1Z,7NZ0,7NZ3,1UEV,3T0Z,2F43,2QUI,7ZH9,8BI0,1E79,5U03,4TQD,7PO3,7RES,6CMW,2Z1U,7UJP,7UJT,7P3F,7P3N,4WAE,1TFW,1A0I,1DEJ,4M3Y,4XVU,6NOO,6NOP,6NO7,3UMP,3UMO,5J1T,8ESC,4EAJ,4EAK,4EAH,4EAG,7RAV,3G6V,6KSH,8E9B,1R9T,7MD2,6AEC,3NCQ,3MN6,3MN7,3MN5,3MN9,3UQE,3UQD,5WC0,6SYT,5WCB,4H0T,4H0V,4H0X,4H0Y,4H03,1PK8,7WYX,2FSG,7BT2,7WPT,7WPX,7WPN,7WPL,8DAV,3EQB,8CVT,4KH0,2PAV,2PAA,5EOU,5OTR,2O0H,6PAO,6PAN,6PAQ,5XVU,5FWP,5FWK,5FWL,5FWM,7CM9,7K3Z,4UP9,1TID,7Z5J,1RFQ,6ZSP,5JRJ,5LVP,5D15,6GRG,7MI6,7MI3,3SJH,2AQX,4Z94,6RJ4,3TLX,4O4F,4O4E,4O4D,7W1Y,4AN3,4KGM,4KGV,2PZE,2PZF,2PZG,3Q53,3LKI,3LKK,6PZ9,4XHO,6PZA,6PZI,7NK7,7CFI,3QO3,3QO7,7NZM,7EER,5YA1,6JD4,6JD5,5IE2,6ZXF,6ZXG,6ZXH,8DAS,8DAT,1SU2,3WQU,7QBA,5DRD,5DR2,7QO6,2R9V,4FO0,7V00,6N2Z,4FWM,1Y8R,1Y8P,1Y8Q,7KO2,7LHT,7LHW,1NYR,6BHU,6TQE,4M3T,4M3U,4M3W,4M3R,4M3X,4M3Z,2P55,1IJJ,5YZG,6JIU,6JIY,6JII,6JI0,6ZM6,6ZM5,5O5W,1F9A,8AAZ,4DLK,7QO5,7QO4,7B93,7M6L,7PW7,7M6A,7DYI,7DYE,7K2T,3C9R,1MDU,1KO5,3PGK,4AT8,4AT1,1XKV,8G8F,5XMI,5XMK,1Z0S,7VX8,7N1P,1RYR,1RYS,4FF3,6W23,6W22,6W21,6W20,6W24,4FFR,5VQA,4BJR,8DGC,4F93,6X2N,5ZTB,7R8E,7XA9,3FDX,1MIW,2Z08,2Z02,6CN2,7UIR,7P48,4KR7,3PJR,7PJI,2HMP,2HMU,2HMW,5EXY,4U07,4U0M,1WUA,7SHM,5ECK,5ECI,5ECH,5ECN,7Q6I,5LIL,7Q6F,7Q6D,3ULE,4KB6,7RGQ,6VOM,6VOL,6VOO,6VON,6VOI,6VOH,6VOK,6VOJ,6VOG,6VOF,3DKC,2GNK,3MMV,7LJF,2WPD,5V2L,5XZ9,1PHK,6O1V,7VAL,8A5P,8A5Q,1QZ5,1QZ6,3EPS,5LUH,4XBR,7PUP,7PUB,1YP3,6MAT,5X9G,5X9H,7P3W,8EOP,1LHR,1RGI,6ZR2,7WIT,3A7H,1L2T,6VTD,6VTB,7TVE,5I9E,4DQW,3CI1,3CI5,3CI4,3CIP,3CIS,6AH5,6AH4,2A84,7RZY,6RIS,6RIQ,4ZS4,2IA6,2IAJ,3ZS7,3LL3,4M9Z,4M9X,4M9Y,4M9S,7T0V,5LVO,8BX8,1MB9,2YXU,3QNO,3AB8,7ESB,2Y27,6JCU,2C01,7TCH,2C96,6Z1P,6R4S,7KL1,1ZYD,7PLJ,3M9O,4RTF,2XCW,3V01,3V04,2R86,2ILY,1N48,7W3M,7W3B,7LI3,7LI4,3Q9L,1R8B,5DK4,7U2X,2X15,5I4N,4P33,5YUD,6JH6,6JH8,6JH9,6U0M,8DGF,6IFR,2FGH,3W3D,7RL0,1ASZ,6CTA,3IQ0,4WH3,5GQL,5GQJ,8BD6,8BD4,8BD5,6TE0,4V02,4V0U,3GQK,1FQ1,6HBU,3QX9,3QXC,1U9I,5CSH,4TU0,2W00,2W02,3U8X,4ZGN,7NXV,2FF3,7K58,5T0G,5T0C,5T0J,5T0I,4GT3,7K5B,6FZB,4RQV,5ZUA,5U2H,7WIW,6RDW,7OIM,5A9P,1B8A,5A99,5A98,3X2W,3X2V,3X2U,6COM,7P5Z,7P52,7P50,2PNN,4XTR,4U1R,7ZZ3,7ZZ4,4A6X,4CBX,4CBU,4CBW,4CB0,3UC5,8FZQ,7D7Y,2RSF,6P8V,5KOY,6P80,3FPB,6EMA,2EWW,4G5Y,7ORJ,7ORK,7ORN,1B38,1B39,5Z68,5Z6R,7SXO,2PC9,7UO7,7PVN,1V1B,5L9N,3KE5,3KEU,4FXF,7NJL,7NJO,7NJN,7NJK,7NJQ,7NJS,6ZQN,5XJC,3DGL,2QKM,2QK4,2GBL,3SL2,6FML,7KZU,7KZI,5ACK,3CHW,5MWL,5MW8,5H67,5GJC,8BWY,3M3N,4HUT,7RCK,2ZHZ,7PSA,6WA8,6OIF,2OOY,4M63,7LG5,7LGQ,7LGM,6TDU,6TDY,3LMI,7JPS,7JPR,7JPQ,7JPP,7JPO,7JPN,6AWH,6AWG,4JYZ,5LXQ,6YII,6MM2,4CT2,4CT1,7T65,4CTA,6JBJ,6JBK,6JBD,3QB0,7Z3O,4IFE,3J2T,6IP2,7N74,5SVK,2A42,2A41,2A40,5OBJ,5NBN,5NBM,5NBL,1AYL,7VX0,7N6I,1KXP,1N5I,1N56,6N0T,7LJL,1V3S,7U1E,7U1S,7U1Q,2X0Q,3U9D,6AZ0,5CE3,1TQP,8APF,6JWY,6JWQ,6JWS,6JWT,6JWW,6JWV,5D4C,2XSZ,6U1D,6U1E,6U1F	5957	160845582	15422				C03517		1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50907145	Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CO[P@](O)(=O)O[P@@](O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O	InChI=1S/C10H16N5O13P3/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1	ZKHQWZAMYRWXGA-KQYNXXCUSA-N	50366480	ADENOSINE TRIPHOSPHATE::ATP	MAP kinase-activated protein kinase 2	Homo sapiens		 12000							ChEMBL	10.1016/j.bmcl.2009.10.102	10.7270/Q24M95GT	19919896			Argiriadi, MA; Ericsson, AM; Harris, CM; Banach, DL; Borhani, DW; Calderwood, DJ; Demers, MD; Dimauro, J; Dixon, RW; Hardman, J; Kwak, S; Li, B; Mankovich, JA; Marcotte, D; Mullen, KD; Ni, B; Pietras, M; Sadhukhan, R; Sousa, S; Tomlinson, MJ; Wang, L; Xiang, T; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50366480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50366480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	ATP	7UT9,1Y64,7LNU,7LN3,7LN2,7LN1,7LN0,7LN6,7LN5,7LN4,1NGE,1NGF,1NGG,1NGH,3LTA,3LTC,2NPI,2ZDQ,7NHL,1GY3,6J18,6J17,1G3I,7SGL,2BU2,2Q7G,2BUP,3H8V,6GFA,7QI6,7QI4,1H8H,4AUI,1FMW,1XDP,7ZSE,3O8L,5HNV,7ABR,3EHG,1KAZ,1KAY,1KAX,7R31,7U6Y,6TAY,6TAX,6DDZ,1XMI,1XMJ,6E0O,4A8M,4A8F,4A8Y,4A8Q,4A8S,4A8W,7JIJ,7CRC,7EKL,8H99,7N30,7N31,6YWX,6YWY,6YWE,6YW6,6YW7,6YW5,4B2Q,2W5G,2W5I,3HBT,8DAR,3CQD,4QC2,1Q97,4GY2,6FU2,1E4G,3FFK,3JZM,4CI6,1MO8,4QNR,6D3S,6D3R,7P2E,7P2Y,7V2Z,5ECQ,5ECP,4XWO,4XW5,2VHT,2VHQ,6NHX,6NHZ,6KCL,6KCM,6KC0,7JM6,7JM7,6MT9,1U5R,1I7L,1OL6,6JRS,7D4O,7D4U,7T3U,1ZAO,1Q24,6ZQM,3A5N,1PJ4,7AI5,3TPQ,7C1Z,4Q4Z,1B0U,7OQH,7LJ1,6P8J,3DGO,6ZO4,5FV0,6L59,6L57,4X6R,3R1R,7PX9,7U9X,7WTD,7WTE,7U9T,7U9K,2BBT,2BBS,2BBO,6ZTQ,4O0M,6GFH,1JKN,7NGF,7MJP,7MJQ,7MJO,1UF9,5AFU,7KSM,6UDQ,6RKE,6RKD,6RKA,7VVY,7VVZ,1KVK,4H4K,7OZ1,2OLQ,2OLR,7UUX,1NMD,1NM1,3Q60,7OIK,3BG5,3E1Y,7CGN,4GP7,1RDQ,2Q97,6ZYW,6ZYY,7W79,4DX2,3WVL,1SVM,3WV9,4DXL,6Z3R,6IUB,6IUC,5N9X,1HLU,7VLR,3JAY,6QRI,6QDV,3V2U,7AT1,7L1R,7L1S,7L1Q,6S47,6N30,7AM2,6OA9,7YFP,7YFN,7S61,7S67,7Y38,7RFH,7RFE,7RFG,6O75,6O78,1P8Z,6PTN,6PTO,7WPM,5FL7,3QUO,3QUN,4AZW,6YAR,6YAY,1G21,7EV2,7EV3,7M74,2BTF,3REP,3REU,8FHN,8FHO,7AIR,7AIQ,7AIP,3W1G,4TL7,1HCK,6HZM,7DC8,7RNR,4WTV,1AQ2,6N2Y,1NSF,1NSY,2CG9,7JGR,7JGA,5CYR,1YXQ,7FDV,7WAJ,6AB0,6AB2,6AB8,6ABK,3H5N,6YT3,6W18,6W17,6W1Z,7NZ0,7NZ3,1UEV,3T0Z,2F43,2QUI,7ZH9,8BI0,1E79,5U03,4TQD,7PO3,7RES,6CMW,2Z1U,7UJP,7UJT,7P3F,7P3N,4WAE,1TFW,1A0I,1DEJ,4M3Y,4XVU,6NOO,6NOP,6NO7,3UMP,3UMO,5J1T,8ESC,4EAJ,4EAK,4EAH,4EAG,7RAV,3G6V,6KSH,8E9B,1R9T,7MD2,6AEC,3NCQ,3MN6,3MN7,3MN5,3MN9,3UQE,3UQD,5WC0,6SYT,5WCB,4H0T,4H0V,4H0X,4H0Y,4H03,1PK8,7WYX,2FSG,7BT2,7WPT,7WPX,7WPN,7WPL,8DAV,3EQB,8CVT,4KH0,2PAV,2PAA,5EOU,5OTR,2O0H,6PAO,6PAN,6PAQ,5XVU,5FWP,5FWK,5FWL,5FWM,7CM9,7K3Z,4UP9,1TID,7Z5J,1RFQ,6ZSP,5JRJ,5LVP,5D15,6GRG,7MI6,7MI3,3SJH,2AQX,4Z94,6RJ4,3TLX,4O4F,4O4E,4O4D,7W1Y,4AN3,4KGM,4KGV,2PZE,2PZF,2PZG,3Q53,3LKI,3LKK,6PZ9,4XHO,6PZA,6PZI,7NK7,7CFI,3QO3,3QO7,7NZM,7EER,5YA1,6JD4,6JD5,5IE2,6ZXF,6ZXG,6ZXH,8DAS,8DAT,1SU2,3WQU,7QBA,5DRD,5DR2,7QO6,2R9V,4FO0,7V00,6N2Z,4FWM,1Y8R,1Y8P,1Y8Q,7KO2,7LHT,7LHW,1NYR,6BHU,6TQE,4M3T,4M3U,4M3W,4M3R,4M3X,4M3Z,2P55,1IJJ,5YZG,6JIU,6JIY,6JII,6JI0,6ZM6,6ZM5,5O5W,1F9A,8AAZ,4DLK,7QO5,7QO4,7B93,7M6L,7PW7,7M6A,7DYI,7DYE,7K2T,3C9R,1MDU,1KO5,3PGK,4AT8,4AT1,1XKV,8G8F,5XMI,5XMK,1Z0S,7VX8,7N1P,1RYR,1RYS,4FF3,6W23,6W22,6W21,6W20,6W24,4FFR,5VQA,4BJR,8DGC,4F93,6X2N,5ZTB,7R8E,7XA9,3FDX,1MIW,2Z08,2Z02,6CN2,7UIR,7P48,4KR7,3PJR,7PJI,2HMP,2HMU,2HMW,5EXY,4U07,4U0M,1WUA,7SHM,5ECK,5ECI,5ECH,5ECN,7Q6I,5LIL,7Q6F,7Q6D,3ULE,4KB6,7RGQ,6VOM,6VOL,6VOO,6VON,6VOI,6VOH,6VOK,6VOJ,6VOG,6VOF,3DKC,2GNK,3MMV,7LJF,2WPD,5V2L,5XZ9,1PHK,6O1V,7VAL,8A5P,8A5Q,1QZ5,1QZ6,3EPS,5LUH,4XBR,7PUP,7PUB,1YP3,6MAT,5X9G,5X9H,7P3W,8EOP,1LHR,1RGI,6ZR2,7WIT,3A7H,1L2T,6VTD,6VTB,7TVE,5I9E,4DQW,3CI1,3CI5,3CI4,3CIP,3CIS,6AH5,6AH4,2A84,7RZY,6RIS,6RIQ,4ZS4,2IA6,2IAJ,3ZS7,3LL3,4M9Z,4M9X,4M9Y,4M9S,7T0V,5LVO,8BX8,1MB9,2YXU,3QNO,3AB8,7ESB,2Y27,6JCU,2C01,7TCH,2C96,6Z1P,6R4S,7KL1,1ZYD,7PLJ,3M9O,4RTF,2XCW,3V01,3V04,2R86,2ILY,1N48,7W3M,7W3B,7LI3,7LI4,3Q9L,1R8B,5DK4,7U2X,2X15,5I4N,4P33,5YUD,6JH6,6JH8,6JH9,6U0M,8DGF,6IFR,2FGH,3W3D,7RL0,1ASZ,6CTA,3IQ0,4WH3,5GQL,5GQJ,8BD6,8BD4,8BD5,6TE0,4V02,4V0U,3GQK,1FQ1,6HBU,3QX9,3QXC,1U9I,5CSH,4TU0,2W00,2W02,3U8X,4ZGN,7NXV,2FF3,7K58,5T0G,5T0C,5T0J,5T0I,4GT3,7K5B,6FZB,4RQV,5ZUA,5U2H,7WIW,6RDW,7OIM,5A9P,1B8A,5A99,5A98,3X2W,3X2V,3X2U,6COM,7P5Z,7P52,7P50,2PNN,4XTR,4U1R,7ZZ3,7ZZ4,4A6X,4CBX,4CBU,4CBW,4CB0,3UC5,8FZQ,7D7Y,2RSF,6P8V,5KOY,6P80,3FPB,6EMA,2EWW,4G5Y,7ORJ,7ORK,7ORN,1B38,1B39,5Z68,5Z6R,7SXO,2PC9,7UO7,7PVN,1V1B,5L9N,3KE5,3KEU,4FXF,7NJL,7NJO,7NJN,7NJK,7NJQ,7NJS,6ZQN,5XJC,3DGL,2QKM,2QK4,2GBL,3SL2,6FML,7KZU,7KZI,5ACK,3CHW,5MWL,5MW8,5H67,5GJC,8BWY,3M3N,4HUT,7RCK,2ZHZ,7PSA,6WA8,6OIF,2OOY,4M63,7LG5,7LGQ,7LGM,6TDU,6TDY,3LMI,7JPS,7JPR,7JPQ,7JPP,7JPO,7JPN,6AWH,6AWG,4JYZ,5LXQ,6YII,6MM2,4CT2,4CT1,7T65,4CTA,6JBJ,6JBK,6JBD,3QB0,7Z3O,4IFE,3J2T,6IP2,7N74,5SVK,2A42,2A41,2A40,5OBJ,5NBN,5NBM,5NBL,1AYL,7VX0,7N6I,1KXP,1N5I,1N56,6N0T,7LJL,1V3S,7U1E,7U1S,7U1Q,2X0Q,3U9D,6AZ0,5CE3,1TQP,8APF,6JWY,6JWQ,6JWS,6JWT,6JWW,6JWV,5D4C,2XSZ,6U1D,6U1E,6U1F	5957	160845582	15422				C03517		1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50907146	CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	HKSZLNNOFSGOKW-ZGQXJOJZSA-N	50059889	(staurosporine)3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::12-[3-methoxy-2,6-dimethyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::12-[3-methoxy-6-methyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::15,16-dimethoxy-15-methyl-17-methylamino-(15S)-4,14,20-triazaheptacyclo[12.12.2.02,6.07,28.08,13.020,27.021,26]octacosa-1(27),2(6),7(28),8(13),9,11,21(26),22,24-nonaen-3-one::2-Amino-4-(2-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one(Staurosporine)::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-::AM-2282::CHEMBL162::Indolocarbazole nitrogen derivative::Isoindolinone Urea derivative::staurosporin	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1016/j.bmcl.2009.10.102	10.7270/Q24M95GT	19919896			Argiriadi, MA; Ericsson, AM; Harris, CM; Banach, DL; Borhani, DW; Calderwood, DJ; Demers, MD; Dimauro, J; Dixon, RW; Hardman, J; Kwak, S; Li, B; Mankovich, JA; Marcotte, D; Mullen, KD; Ni, B; Pietras, M; Sadhukhan, R; Sousa, S; Tomlinson, MJ; Wang, L; Xiang, T; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44299148	103955664		CHEMBL162			C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50907147	CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	HKSZLNNOFSGOKW-ZGQXJOJZSA-N	50059889	(staurosporine)3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::12-[3-methoxy-2,6-dimethyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::12-[3-methoxy-6-methyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::15,16-dimethoxy-15-methyl-17-methylamino-(15S)-4,14,20-triazaheptacyclo[12.12.2.02,6.07,28.08,13.020,27.021,26]octacosa-1(27),2(6),7(28),8(13),9,11,21(26),22,24-nonaen-3-one::2-Amino-4-(2-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one(Staurosporine)::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-::AM-2282::CHEMBL162::Indolocarbazole nitrogen derivative::Isoindolinone Urea derivative::staurosporin	MAP kinase-activated protein kinase 2	Homo sapiens		 660							ChEMBL	10.1016/j.bmcl.2009.10.102	10.7270/Q24M95GT	19919896			Argiriadi, MA; Ericsson, AM; Harris, CM; Banach, DL; Borhani, DW; Calderwood, DJ; Demers, MD; Dimauro, J; Dixon, RW; Hardman, J; Kwak, S; Li, B; Mankovich, JA; Marcotte, D; Mullen, KD; Ni, B; Pietras, M; Sadhukhan, R; Sousa, S; Tomlinson, MJ; Wang, L; Xiang, T; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44299148	103955664		CHEMBL162			C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50907148	CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	HKSZLNNOFSGOKW-ZGQXJOJZSA-N	50059889	(staurosporine)3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::12-[3-methoxy-2,6-dimethyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::12-[3-methoxy-6-methyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::15,16-dimethoxy-15-methyl-17-methylamino-(15S)-4,14,20-triazaheptacyclo[12.12.2.02,6.07,28.08,13.020,27.021,26]octacosa-1(27),2(6),7(28),8(13),9,11,21(26),22,24-nonaen-3-one::2-Amino-4-(2-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one(Staurosporine)::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-::AM-2282::CHEMBL162::Indolocarbazole nitrogen derivative::Isoindolinone Urea derivative::staurosporin	MAP kinase-activated protein kinase 2	Homo sapiens		 1700							ChEMBL	10.1016/j.bmcl.2009.10.102	10.7270/Q24M95GT	19919896			Argiriadi, MA; Ericsson, AM; Harris, CM; Banach, DL; Borhani, DW; Calderwood, DJ; Demers, MD; Dimauro, J; Dixon, RW; Hardman, J; Kwak, S; Li, B; Mankovich, JA; Marcotte, D; Mullen, KD; Ni, B; Pietras, M; Sadhukhan, R; Sousa, S; Tomlinson, MJ; Wang, L; Xiang, T; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44299148	103955664		CHEMBL162			C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50907149	CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	HKSZLNNOFSGOKW-ZGQXJOJZSA-N	50059889	(staurosporine)3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::12-[3-methoxy-2,6-dimethyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::12-[3-methoxy-6-methyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::15,16-dimethoxy-15-methyl-17-methylamino-(15S)-4,14,20-triazaheptacyclo[12.12.2.02,6.07,28.08,13.020,27.021,26]octacosa-1(27),2(6),7(28),8(13),9,11,21(26),22,24-nonaen-3-one::2-Amino-4-(2-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one(Staurosporine)::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-::AM-2282::CHEMBL162::Indolocarbazole nitrogen derivative::Isoindolinone Urea derivative::staurosporin	MAP kinase-activated protein kinase 2	Homo sapiens		 3400							ChEMBL	10.1016/j.bmcl.2009.10.102	10.7270/Q24M95GT	19919896			Argiriadi, MA; Ericsson, AM; Harris, CM; Banach, DL; Borhani, DW; Calderwood, DJ; Demers, MD; Dimauro, J; Dixon, RW; Hardman, J; Kwak, S; Li, B; Mankovich, JA; Marcotte, D; Mullen, KD; Ni, B; Pietras, M; Sadhukhan, R; Sousa, S; Tomlinson, MJ; Wang, L; Xiang, T; Talanian, RV	Abbott Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44299148	103955664		CHEMBL162			C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50917061	O=C1NCCc2[nH]c(cc12)-c1ccncc1	InChI=1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)	DKXHSOUZPMHNIZ-UHFFFAOYSA-N	27344	2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one::JMC502647 Compound 8::Pyrrolopyridinone, 1	MAP kinase-activated protein kinase 2	Homo sapiens		 470							ChEMBL	10.1038/nchembio.90	10.7270/Q2DV1KVK	18469809			Montagnoli, A; Valsasina, B; Croci, V; Menichincheri, M; Rainoldi, S; Marchesi, V; Tibolla, M; Tenca, P; Brotherton, D; Albanese, C; Patton, V; Alzani, R; Ciavolella, A; Sola, F; Molinari, A; Volpi, D; Avanzi, N; Fiorentini, F; Cattoni, M; Healy, S; Ballinari, D; Pesenti, E; Isacchi, A; Moll, J; Bensimon, A; Vanotti, E; Santocanale, C	Nerviano Medical Sciences Oncology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=27344	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=27344&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	0SY	4F9B	11715767	57299053						ZINC16052718	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50905001	CN1CCN(Cc2ccc3oc(cc3c2)-c2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1	InChI=1S/C29H28N6O/c1-19-23-7-8-32-26(23)5-4-25(19)33-29-22(15-30)16-31-17-24(29)28-14-21-13-20(3-6-27(21)36-28)18-35-11-9-34(2)10-12-35/h3-8,13-14,16-17,32H,9-12,18H2,1-2H3,(H,31,33)	DZIUPOCVDSYPSY-UHFFFAOYSA-N	50302042	4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpiperazin-1-yl)methyl)benzofuran-2-yl)nicotinonitrile::CHEMBL571581	MAP kinase-activated protein kinase 2	Homo sapiens		>9000							ChEMBL	10.1016/j.bmcl.2009.07.113	10.7270/Q2QR4Z2Q	19703774			Prashad, AS; Wang, D; Subrath, J; Wu, B; Lin, M; Zhang, MY; Kagan, N; Lee, J; Yang, X; Brennan, A; Chaudhary, D; Xu, X; Leung, L; Wang, J; Boschelli, DH	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50302042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50302042&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			23627212	104156403		CHEMBL571581				ZINC45288050	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50906401	CC1(C)CC(CC(C)(C)N1[O])NC(=O)c1cccc(c1)-c1cc2nccc(Nc3cccc(O)c3)n2n1	InChI=1S/C28H31N6O3/c1-27(2)16-21(17-28(3,4)34(27)37)31-26(36)19-8-5-7-18(13-19)23-15-25-29-12-11-24(33(25)32-23)30-20-9-6-10-22(35)14-20/h5-15,21,30,35H,16-17H2,1-4H3,(H,31,36)	GNIYUURCQFKRCB-UHFFFAOYSA-N	50378568	CHEMBL1163016	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1021/jm901525b	10.7270/Q2QJ7J72	20038108			Moy, FJ; Lee, A; Gavrin, LK; Xu, ZB; Sievers, A; Kieras, E; Stochaj, W; Mosyak, L; McKew, J; Tsao, DH	Wyeth Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50378568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50378568&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46179972	160857651		CHEMBL1163016					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927282	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	CAIGVNVLJGDZSF-UHFFFAOYSA-N	50362169	CHEMBL1938680	MAP kinase-activated protein kinase 2	Homo sapiens		 5000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362169&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401151	136966231		CHEMBL1938680				ZINC73224553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927293	CN1CCN(CC1)c1ccc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1	InChI=1S/C22H22ClN3O2/c1-25-12-14-26(15-13-25)19-8-6-18(7-9-19)24-22(27)21-11-10-20(28-21)16-2-4-17(23)5-3-16/h2-11H,12-15H2,1H3,(H,24,27)	QONRQALSXOAURD-UHFFFAOYSA-N	51932	5-(4-chlorophenyl)-N-[4-(4-methyl-1-piperazinyl)phenyl]-2-furancarboxamide::5-(4-chlorophenyl)-N-[4-(4-methylpiperazin-1-yl)phenyl]furan-2-carboxamide::5-(4-chlorophenyl)-N-[4-(4-methylpiperazino)phenyl]-2-furamide::CHEMBL1392696::MLS001125449::SMR000665983::cid_1494312	MAP kinase-activated protein kinase 2	Homo sapiens		 6000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=51932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=51932&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			1494312	252632089		CHEMBL1392696				ZINC13124188	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927295	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1=O	InChI=1S/C21H18ClN3O3/c22-15-3-1-14(2-4-15)18-9-10-19(28-18)21(27)24-16-5-7-17(8-6-16)25-12-11-23-13-20(25)26/h1-10,23H,11-13H2,(H,24,27)	YVHSGWHHBUBSBO-UHFFFAOYSA-N	50380299	CHEMBL2017453	MAP kinase-activated protein kinase 2	Homo sapiens		 15000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380299&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70693786	160859382		CHEMBL2017453				ZINC84616900	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927298	Clc1ccc(cc1)-c1cc(no1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C20H19ClN4O2/c21-15-3-1-14(2-4-15)19-13-18(24-27-19)20(26)23-16-5-7-17(8-6-16)25-11-9-22-10-12-25/h1-8,13,22H,9-12H2,(H,23,26)	NQRMAIQQUZVZOY-UHFFFAOYSA-N	50380302	CHEMBL2017456	MAP kinase-activated protein kinase 2	Homo sapiens		 7500							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380302&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689582	160859385		CHEMBL2017456				ZINC84616903	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927299	Clc1ccc(cc1)-c1cccc(n1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H21ClN4O/c23-17-6-4-16(5-7-17)20-2-1-3-21(26-20)22(28)25-18-8-10-19(11-9-18)27-14-12-24-13-15-27/h1-11,24H,12-15H2,(H,25,28)	PDVROLFZQHGTNZ-UHFFFAOYSA-N	50380303	CHEMBL2017457	MAP kinase-activated protein kinase 2	Homo sapiens		 11000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380303&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70695897	160859386		CHEMBL2017457				ZINC84635929	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927303	CN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C22H22ClN3O2/c1-25(18-6-8-19(9-7-18)26-14-12-24-13-15-26)22(27)21-11-10-20(28-21)16-2-4-17(23)5-3-16/h2-11,24H,12-15H2,1H3	VVLMVMQNQKVXTF-UHFFFAOYSA-N	50380304	CHEMBL2017458	MAP kinase-activated protein kinase 2	Homo sapiens		 600							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380304&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689583	160859387		CHEMBL2017458				ZINC84635931	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927304	CCN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C23H24ClN3O2/c1-2-27(20-9-7-19(8-10-20)26-15-13-25-14-16-26)23(28)22-12-11-21(29-22)17-3-5-18(24)6-4-17/h3-12,25H,2,13-16H2,1H3	ZQXYAXCRCBTDIH-UHFFFAOYSA-N	50380305	CHEMBL2017459	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380305&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70695898	160859388		CHEMBL2017459				ZINC84596616	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927305	CCCN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C24H26ClN3O2/c1-2-15-28(21-9-7-20(8-10-21)27-16-13-26-14-17-27)24(29)23-12-11-22(30-23)18-3-5-19(25)6-4-18/h3-12,26H,2,13-17H2,1H3	KASPOQKBLGLGBP-UHFFFAOYSA-N	50380306	CHEMBL2017460	MAP kinase-activated protein kinase 2	Homo sapiens		 650							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380306&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691712	160859389		CHEMBL2017460				ZINC84596801	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927306	CC(C)N(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C24H26ClN3O2/c1-17(2)28(21-9-7-20(8-10-21)27-15-13-26-14-16-27)24(29)23-12-11-22(30-23)18-3-5-19(25)6-4-18/h3-12,17,26H,13-16H2,1-2H3	YFRABOFOMDNCOG-UHFFFAOYSA-N	50380307	CHEMBL2017461	MAP kinase-activated protein kinase 2	Homo sapiens		 1200							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380307&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685388	160859390		CHEMBL2017461				ZINC84633522	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927307	CCCCN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C25H28ClN3O2/c1-2-3-16-29(22-10-8-21(9-11-22)28-17-14-27-15-18-28)25(30)24-13-12-23(31-24)19-4-6-20(26)7-5-19/h4-13,27H,2-3,14-18H2,1H3	RWGDJQOBAYWTBP-UHFFFAOYSA-N	50380308	CHEMBL2017462	MAP kinase-activated protein kinase 2	Homo sapiens		 440							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380308&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691713	160859391		CHEMBL2017462				ZINC84633523	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927308	Cn1ccnc1CN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C26H26ClN5O2/c1-30-15-14-29-25(30)18-32(22-8-6-21(7-9-22)31-16-12-28-13-17-31)26(33)24-11-10-23(34-24)19-2-4-20(27)5-3-19/h2-11,14-15,28H,12-13,16-18H2,1H3	XBEPLNIHFRVFRL-UHFFFAOYSA-N	50380309	CHEMBL2017463	MAP kinase-activated protein kinase 2	Homo sapiens		 100							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380309&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70687522	160859392		CHEMBL2017463				ZINC84634034	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927310	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccncc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-22-3-1-21(2-4-22)25-9-10-26(34-25)27(33)32(19-20-11-13-29-14-12-20)24-7-5-23(6-8-24)31-17-15-30-16-18-31/h1-14,30H,15-19H2	MTGHRYOPMOQODT-UHFFFAOYSA-N	50380310	CHEMBL2017619	MAP kinase-activated protein kinase 2	Homo sapiens		 90							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380310&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689597	160859393		CHEMBL2017619				ZINC84596044	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927312	Clc1ccccc1-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-18-4-2-1-3-17(18)19-9-10-20(27-19)21(26)24-15-5-7-16(8-6-15)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	OAWGNEGVOIDOJR-UHFFFAOYSA-N	50380288	CHEMBL2017442	MAP kinase-activated protein kinase 2	Homo sapiens				>8000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380288&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685385	160859371		CHEMBL2017442				ZINC84587306	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927313	Clc1cccc(c1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-2-15(14-16)19-8-9-20(27-19)21(26)24-17-4-6-18(7-5-17)25-12-10-23-11-13-25/h1-9,14,23H,10-13H2,(H,24,26)	PPDZWHVZYSPBOB-UHFFFAOYSA-N	50380289	CHEMBL2017443	MAP kinase-activated protein kinase 2	Homo sapiens				>5000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380289&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691708	160859372		CHEMBL2017443				ZINC84619537	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927314	Clc1ccc(-c2ccc(o2)C(=O)Nc2ccc(cc2)N2CCNCC2)c(Cl)c1	InChI=1S/C21H19Cl2N3O2/c22-14-1-6-17(18(23)13-14)19-7-8-20(28-19)21(27)25-15-2-4-16(5-3-15)26-11-9-24-10-12-26/h1-8,13,24H,9-12H2,(H,25,27)	GJQZQVRIRSQPIP-UHFFFAOYSA-N	50380290	CHEMBL2017444	MAP kinase-activated protein kinase 2	Homo sapiens				 1600					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380290&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70687520	160859373		CHEMBL2017444				ZINC84617753	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927315	Cc1cc(Cl)ccc1-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H22ClN3O2/c1-15-14-16(23)2-7-19(15)20-8-9-21(28-20)22(27)25-17-3-5-18(6-4-17)26-12-10-24-11-13-26/h2-9,14,24H,10-13H2,1H3,(H,25,27)	JBPZEDJNSIAVPF-UHFFFAOYSA-N	50380291	CHEMBL2017445	MAP kinase-activated protein kinase 2	Homo sapiens				 1400					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380291&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691709	160859374		CHEMBL2017445				ZINC84587309	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927316	FC(F)(F)c1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H20F3N3O2/c23-22(24,25)16-3-1-15(2-4-16)19-9-10-20(30-19)21(29)27-17-5-7-18(8-6-17)28-13-11-26-12-14-28/h1-10,26H,11-14H2,(H,27,29)	FRYRKVNSTORMGJ-UHFFFAOYSA-N	50380292	CHEMBL2017446	MAP kinase-activated protein kinase 2	Homo sapiens				>7700					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380292&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691710	160859375		CHEMBL2017446				ZINC84617207	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927317	COc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C22H23N3O3/c1-27-19-8-2-16(3-9-19)20-10-11-21(28-20)22(26)24-17-4-6-18(7-5-17)25-14-12-23-13-15-25/h2-11,23H,12-15H2,1H3,(H,24,26)	DYJGGYMCCGHJMT-UHFFFAOYSA-N	50380293	CHEMBL2017447	MAP kinase-activated protein kinase 2	Homo sapiens				 8000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380293&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689580	160859376		CHEMBL2017447				ZINC84617209	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927318	Clc1ccc(s1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C19H18ClN3O2S/c20-18-8-7-17(26-18)15-5-6-16(25-15)19(24)22-13-1-3-14(4-2-13)23-11-9-21-10-12-23/h1-8,21H,9-12H2,(H,22,24)	RMSJFISUQPTNAQ-UHFFFAOYSA-N	50380294	CHEMBL2017448	MAP kinase-activated protein kinase 2	Homo sapiens				>8000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380294&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689581	160859377		CHEMBL2017448				ZINC84619457	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927319	Fc1cc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)ccc1N1CCNCC1	InChI=1S/C21H19ClFN3O2/c22-15-3-1-14(2-4-15)19-7-8-20(28-19)21(27)25-16-5-6-18(17(23)13-16)26-11-9-24-10-12-26/h1-8,13,24H,9-12H2,(H,25,27)	IMZWHTLABIYNHC-UHFFFAOYSA-N	50380295	CHEMBL2017449	MAP kinase-activated protein kinase 2	Homo sapiens				>3400					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380295&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685386	160859378		CHEMBL2017449				ZINC84636070	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927320	FC(F)(F)c1cc(ccc1NC(=O)c1ccc(o1)-c1ccc(Cl)cc1)N1CCNCC1	InChI=1S/C22H19ClF3N3O2/c23-15-3-1-14(2-4-15)19-7-8-20(31-19)21(30)28-18-6-5-16(13-17(18)22(24,25)26)29-11-9-27-10-12-29/h1-8,13,27H,9-12H2,(H,28,30)	XMDGCSWRCZWUON-UHFFFAOYSA-N	50380296	CHEMBL2017450	MAP kinase-activated protein kinase 2	Homo sapiens				>8000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380296&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70687521	160859379		CHEMBL2017450				ZINC84617210	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927321	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)C1=CCNCC1	InChI=1S/C22H19ClN2O2/c23-18-5-1-17(2-6-18)20-9-10-21(27-20)22(26)25-19-7-3-15(4-8-19)16-11-13-24-14-12-16/h1-11,24H,12-14H2,(H,25,26)	CKDXGBVERZNORW-UHFFFAOYSA-N	50380298	CHEMBL2017452	MAP kinase-activated protein kinase 2	Homo sapiens				 1300					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380298&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70691711	160859381		CHEMBL2017452				ZINC84635037	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927322	OC1CCN(CC1)c1ccc(NC(=O)c2ccc(o2)-c2ccc(Cl)cc2)cc1	InChI=1S/C22H21ClN2O3/c23-16-3-1-15(2-4-16)20-9-10-21(28-20)22(27)24-17-5-7-18(8-6-17)25-13-11-19(26)12-14-25/h1-10,19,26H,11-14H2,(H,24,27)	FVADYYQYUBQSIE-UHFFFAOYSA-N	50380311	CHEMBL2017451	MAP kinase-activated protein kinase 2	Homo sapiens		>20000							ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380311&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683279	160859394		CHEMBL2017451				ZINC48010311	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927323	Clc1ccc(cc1)-c1ccc(s1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3OS/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	FEMAFCHAYMYMMA-UHFFFAOYSA-N	50380300	CHEMBL2017454	MAP kinase-activated protein kinase 2	Homo sapiens				 5000					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380300&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70681191	160859383		CHEMBL2017454				ZINC84586647	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927324	Clc1ccc(cc1)-c1nc(cs1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C20H19ClN4OS/c21-15-3-1-14(2-4-15)20-24-18(13-27-20)19(26)23-16-5-7-17(8-6-16)25-11-9-22-10-12-25/h1-8,13,22H,9-12H2,(H,23,26)	QGNVFBKITUGHJH-UHFFFAOYSA-N	50380301	CHEMBL2017455	MAP kinase-activated protein kinase 2	Homo sapiens				 900					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380301&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70685387	160859384		CHEMBL2017455				ZINC84596668	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50927332	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens				 350					ChEMBL	10.1021/ml200113y	10.7270/Q2J967CS	24900358			Huang, X; Shipps, GW; Cheng, CC; Spacciapoli, P; Zhang, X; McCoy, MA; Wyss, DF; Yang, X; Achab, A; Soucy, K; Montavon, DK; Murphy, DM; Whitehurst, CE	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50932024	Fc1ccc(Sc2ccc3c(-c4c(Cl)cccc4Cl)c(=O)ncn3n2)c(F)c1	InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H	VEPKQEUBKLEPRA-UHFFFAOYSA-N	15244	5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)sulfanyl]-6H-pyrimido[1,6-a]pyridazin-6-one::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6-pyrimido[1,6-b]pyridazinone::5-(2,6-dichlorophenyl)-2-[(2,4-difluorophenyl)thio]pyrimido[1,6-b]pyridazin-6-one::5-(2,6-dichlorophenyl)-9-(2,4-difluorophenyl)sulfanyl-1,3,10-triazabicyclo[4.4.0]deca-2,5,7,9-tetraen-4-one::5-[2,6-bis(chloranyl)phenyl]-2-[2,4-bis(fluoranyl)phenyl]sulfanyl-pyrimido[1,6-b]pyridazin-6-one::VX-745::VX745::cid_3038525	MAP kinase-activated protein kinase 2	Homo sapiens		>5000							ChEMBL	10.1021/ml2001455	10.7270/Q26D5V19	24900264			Duffy, JP; Harrington, EM; Salituro, FG; Cochran, JE; Green, J; Gao, H; Bemis, GW; Evindar, G; Galullo, VP; Ford, PJ; Germann, UA; Wilson, KP; Bellon, SF; Chen, G; Taslimi, P; Jones, P; Huang, C; Pazhanisamy, S; Wang, YM; Murcko, MA; Su, MS	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15244	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=15244&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	52P	3ZSI,3HP5,3FC1	3038525	46515551			DB07138			ZINC13493055	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936846	FC1(F)CCN(CC1)c1ccc(cc1)N1C(ON=C1c1ccc(o1)-c1ccc(Cl)cc1)c1ccncc1	InChI=1S/C28H23ClF2N4O2/c29-21-3-1-19(2-4-21)24-9-10-25(36-24)26-33-37-27(20-11-15-32-16-12-20)35(26)23-7-5-22(6-8-23)34-17-13-28(30,31)14-18-34/h1-12,15-16,27H,13-14,17-18H2	DROFNIUJDSSHNG-UHFFFAOYSA-N	50384540	CHEMBL2036619	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384540	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384540&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692333	160863623		CHEMBL2036619				ZINC84653928	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936847	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1Cc1ccc(cc1)N1CCNCC1)c1ccncc1	InChI=1S/C28H26ClN5O2/c29-23-5-3-21(4-6-23)25-9-10-26(35-25)27-32-36-28(22-11-13-30-14-12-22)34(27)19-20-1-7-24(8-2-20)33-17-15-31-16-18-33/h1-14,28,31H,15-19H2	HFVCVGVPUULPLF-UHFFFAOYSA-N	50384541	CHEMBL2036620	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384541	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384541&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70681767	160863624		CHEMBL2036620				ZINC84653930	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936848	N#Cc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C33H27N7O2/c34-19-23-5-7-24(8-6-23)30-13-14-31(41-30)32-38-42-33(29-4-2-1-3-28(29)25-20-36-22-37-21-25)40(32)27-11-9-26(10-12-27)39-17-15-35-16-18-39/h1-14,20-22,33,35H,15-18H2	ZLCHYXMKVDHWGU-UHFFFAOYSA-N	50384542	CHEMBL2036616	MAP kinase-activated protein kinase 2	Homo sapiens		 8.00							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384542&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57330141	160863625		CHEMBL2036616				ZINC84724597	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936849	N#Cc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C33H27N7O2/c34-19-23-5-7-24(8-6-23)30-13-14-31(41-30)32-38-42-33(29-4-2-1-3-28(29)25-20-36-22-37-21-25)40(32)27-11-9-26(10-12-27)39-17-15-35-16-18-39/h1-14,20-22,33,35H,15-18H2	ZLCHYXMKVDHWGU-UHFFFAOYSA-N	50384542	CHEMBL2036616	MAP kinase-activated protein kinase 2	Homo sapiens		 6.00							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384542&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57330141	160863625		CHEMBL2036616				ZINC84724597	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936850	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens				 350					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936851	Clc1cccc(c1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C32H27ClN6O2/c33-24-5-3-4-22(18-24)29-12-13-30(40-29)31-37-41-32(28-7-2-1-6-27(28)23-19-35-21-36-20-23)39(31)26-10-8-25(9-11-26)38-16-14-34-15-17-38/h1-13,18-21,32,34H,14-17H2	AIOXNMPFHMQKSX-UHFFFAOYSA-N	50384543	CHEMBL2036609	MAP kinase-activated protein kinase 2	Homo sapiens		 1300							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384543&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70688147	160863626		CHEMBL2036609				ZINC84653494	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936852	Fc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C32H27FN6O2/c33-24-7-5-22(6-8-24)29-13-14-30(40-29)31-37-41-32(28-4-2-1-3-27(28)23-19-35-21-36-20-23)39(31)26-11-9-25(10-12-26)38-17-15-34-16-18-38/h1-14,19-21,32,34H,15-18H2	YMDHZMGPKRALSL-UHFFFAOYSA-N	50384544	CHEMBL2036610	MAP kinase-activated protein kinase 2	Homo sapiens		 50							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384544&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683883	160863627		CHEMBL2036610				ZINC84653496	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936853	Clc1ccc(cc1Cl)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C32H26Cl2N6O2/c33-27-10-5-21(17-28(27)34)29-11-12-30(41-29)31-38-42-32(26-4-2-1-3-25(26)22-18-36-20-37-19-22)40(31)24-8-6-23(7-9-24)39-15-13-35-14-16-39/h1-12,17-20,32,35H,13-16H2	VXQBATYBJPWXSC-UHFFFAOYSA-N	50384545	CHEMBL2036611	MAP kinase-activated protein kinase 2	Homo sapiens		 970							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384545	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384545&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70686017	160863628		CHEMBL2036611				ZINC84653498	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936854	Fc1cc(ccc1Cl)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C32H26ClFN6O2/c33-27-10-5-21(17-28(27)34)29-11-12-30(41-29)31-38-42-32(26-4-2-1-3-25(26)22-18-36-20-37-19-22)40(31)24-8-6-23(7-9-24)39-15-13-35-14-16-39/h1-12,17-20,32,35H,13-16H2	TYJLQBFGIJNZAL-UHFFFAOYSA-N	50384546	CHEMBL2036612	MAP kinase-activated protein kinase 2	Homo sapiens		 220							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384546	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384546&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70694395	160863629		CHEMBL2036612				ZINC84709172	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936855	C1CN(CCN1)c1ccc(cc1)N1C(ON=C1c1ccc(o1)-c1ccncc1)c1ccccc1-c1cncnc1	InChI=1S/C31H27N7O2/c1-2-4-27(26(3-1)23-19-34-21-35-20-23)31-38(25-7-5-24(6-8-25)37-17-15-33-16-18-37)30(36-40-31)29-10-9-28(39-29)22-11-13-32-14-12-22/h1-14,19-21,31,33H,15-18H2	XJPWEUGASNNPSG-UHFFFAOYSA-N	50384547	CHEMBL2036613	MAP kinase-activated protein kinase 2	Homo sapiens		 790							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384547	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384547&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70681766	160863630		CHEMBL2036613				ZINC84709177	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936856	COc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C33H30N6O3/c1-40-27-12-6-23(7-13-27)30-14-15-31(41-30)32-37-42-33(29-5-3-2-4-28(29)24-20-35-22-36-21-24)39(32)26-10-8-25(9-11-26)38-18-16-34-17-19-38/h2-15,20-22,33-34H,16-19H2,1H3	LUVGQMIABQYOSC-UHFFFAOYSA-N	50384548	CHEMBL2036614	MAP kinase-activated protein kinase 2	Homo sapiens		 310							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384548	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384548&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70686018	160863631		CHEMBL2036614				ZINC84710038	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936857	CNC(=O)c1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C34H31N7O3/c1-35-33(42)24-8-6-23(7-9-24)30-14-15-31(43-30)32-39-44-34(29-5-3-2-4-28(29)25-20-37-22-38-21-25)41(32)27-12-10-26(11-13-27)40-18-16-36-17-19-40/h2-15,20-22,34,36H,16-19H2,1H3,(H,35,42)	ZGSCLCGORFILOB-UHFFFAOYSA-N	50384549	CHEMBL2036615	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384549	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384549&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692332	160863632		CHEMBL2036615				ZINC84710042	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936858	N#Cc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C33H27N7O2/c34-19-23-5-7-24(8-6-23)30-13-14-31(41-30)32-38-42-33(29-4-2-1-3-28(29)25-20-36-22-37-21-25)40(32)27-11-9-26(10-12-27)39-17-15-35-16-18-39/h1-14,20-22,33,35H,15-18H2	ZLCHYXMKVDHWGU-UHFFFAOYSA-N	50384542	CHEMBL2036616	MAP kinase-activated protein kinase 2	Homo sapiens		 8							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384542&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57330141	160863625		CHEMBL2036616				ZINC84724597	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936859	N#Cc1cccc(c1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C33H27N7O2/c34-19-23-4-3-5-24(18-23)30-12-13-31(41-30)32-38-42-33(29-7-2-1-6-28(29)25-20-36-22-37-21-25)40(32)27-10-8-26(9-11-27)39-16-14-35-15-17-39/h1-13,18,20-22,33,35H,14-17H2	GFOXUTMJYHNVNY-UHFFFAOYSA-N	50384550	CHEMBL2036617	MAP kinase-activated protein kinase 2	Homo sapiens		 5300							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384550	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384550&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70686019	160863633		CHEMBL2036617				ZINC84653924	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936860	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)C1CCNCC1)c1ccncc1	InChI=1S/C28H25ClN4O2/c29-23-5-1-21(2-6-23)25-9-10-26(34-25)27-32-35-28(22-13-17-31-18-14-22)33(27)24-7-3-19(4-8-24)20-11-15-30-16-12-20/h1-10,13-14,17-18,20,28,30H,11-12,15-16H2	VGQMSEKUQSSVLH-UHFFFAOYSA-N	50384551	CHEMBL2036618	MAP kinase-activated protein kinase 2	Homo sapiens		 190							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384551	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384551&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70686020	160863634		CHEMBL2036618				ZINC84653926	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936861	Clc1ccc(cc1)-c1ccc(o1)C(=O)N(Cc1ccccn1)c1ccc(cc1)N1CCNCC1	InChI=1S/C27H25ClN4O2/c28-21-6-4-20(5-7-21)25-12-13-26(34-25)27(33)32(19-22-3-1-2-14-30-22)24-10-8-23(9-11-24)31-17-15-29-16-18-31/h1-14,29H,15-19H2	LIPNXDIBECKOMJ-UHFFFAOYSA-N	50362106	CHEMBL1938681	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362106	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362106&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53475321	136966168		CHEMBL1938681				ZINC82158411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936862	Clc1ccc(cc1)-c1ccc(o1)-c1nocc1-c1ccc(cc1)N1CCNCC1	InChI=1S/C23H20ClN3O2/c24-18-5-1-17(2-6-18)21-9-10-22(29-21)23-20(15-28-26-23)16-3-7-19(8-4-16)27-13-11-25-12-14-27/h1-10,15,25H,11-14H2	JARONAMHZKWSCA-UHFFFAOYSA-N	50384552	CHEMBL2036449	MAP kinase-activated protein kinase 2	Homo sapiens		 3400							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384552	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384552&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70694383	160863635		CHEMBL2036449				ZINC84669670	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936863	Clc1ccc(cc1)-c1ccc(o1)-c1cc(on1)-c1ccc(cc1)N1CCNCC1	InChI=1S/C23H20ClN3O2/c24-18-5-1-16(2-6-18)21-9-10-22(28-21)20-15-23(29-26-20)17-3-7-19(8-4-17)27-13-11-25-12-14-27/h1-10,15,25H,11-14H2	OXVOXRAOISGECP-UHFFFAOYSA-N	50384553	CHEMBL2036450	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384553	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384553&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70688136	160863636		CHEMBL2036450				ZINC84710096	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936864	Clc1ccc(cc1)-c1ccc(o1)-c1noc(=O)n1-c1ccc(cc1)N1CCNCC1	InChI=1S/C22H19ClN4O3/c23-16-3-1-15(2-4-16)19-9-10-20(29-19)21-25-30-22(28)27(21)18-7-5-17(6-8-18)26-13-11-24-12-14-26/h1-10,24H,11-14H2	NWWGWXIYJUQJCJ-UHFFFAOYSA-N	50384554	CHEMBL2036451	MAP kinase-activated protein kinase 2	Homo sapiens		 6200							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384554	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384554&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70688137	160863637		CHEMBL2036451				ZINC84710098	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936865	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1	InChI=1S/C28H25ClN4O2/c29-22-8-6-20(7-9-22)25-14-15-26(34-25)27-31-35-28(21-4-2-1-3-5-21)33(27)24-12-10-23(11-13-24)32-18-16-30-17-19-32/h1-15,28,30H,16-19H2	ZWUWARMSLKVJAD-UHFFFAOYSA-N	50384555	CHEMBL2036452	MAP kinase-activated protein kinase 2	Homo sapiens		 50							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384555&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70686009	160863638		CHEMBL2036452				ZINC84713172	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936866	Clc1ccc(cc1)-c1ccc(o1)C1ON=C(N1c1ccc(cc1)N1CCNCC1)c1ccccc1	InChI=1S/C28H25ClN4O2/c29-22-8-6-20(7-9-22)25-14-15-26(34-25)28-33(27(31-35-28)21-4-2-1-3-5-21)24-12-10-23(11-13-24)32-18-16-30-17-19-32/h1-15,28,30H,16-19H2	LXLBBFUECISSIM-UHFFFAOYSA-N	50384556	CHEMBL2036453	MAP kinase-activated protein kinase 2	Homo sapiens		 3700							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384556	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384556&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683871	160863639		CHEMBL2036453				ZINC84713177	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936867	N#Cc1ccc(cc1)-c1ccc(o1)C1=NOCCN1c1ccc(cc1)N1CCNCC1	InChI=1S/C24H23N5O2/c25-17-18-1-3-19(4-2-18)22-9-10-23(31-22)24-27-30-16-15-29(24)21-7-5-20(6-8-21)28-13-11-26-12-14-28/h1-10,26H,11-16H2	UENAKVJEFCQJHB-UHFFFAOYSA-N	50384557	CHEMBL2036454	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384557	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384557&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692321	160863640		CHEMBL2036454				ZINC84711597	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936868	Clc1ccc(cc1)-c1ccc(o1)C1=NOCCCN1c1ccc(cc1)N1CCNCC1	InChI=1S/C24H25ClN4O2/c25-19-4-2-18(3-5-19)22-10-11-23(31-22)24-27-30-17-1-14-29(24)21-8-6-20(7-9-21)28-15-12-26-13-16-28/h2-11,26H,1,12-17H2	WRMUTPNZHUXZIZ-UHFFFAOYSA-N	50384558	CHEMBL2036455	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384558	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384558&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70696462	160863641		CHEMBL2036455				ZINC84711599	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936869	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccn1	InChI=1S/C27H24ClN5O2/c28-20-6-4-19(5-7-20)24-12-13-25(34-24)26-31-35-27(23-3-1-2-14-30-23)33(26)22-10-8-21(9-11-22)32-17-15-29-16-18-32/h1-14,27,29H,15-18H2	CFHJAKKKDPAQLU-UHFFFAOYSA-N	50384559	CHEMBL2036456	MAP kinase-activated protein kinase 2	Homo sapiens		 30							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384559&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692322	160863642		CHEMBL2036456				ZINC84711602	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936870	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1cccnc1	InChI=1S/C27H24ClN5O2/c28-21-5-3-19(4-6-21)24-11-12-25(34-24)26-31-35-27(20-2-1-13-30-18-20)33(26)23-9-7-22(8-10-23)32-16-14-29-15-17-32/h1-13,18,27,29H,14-17H2	DNAJONSLKKYISL-UHFFFAOYSA-N	50384560	CHEMBL2036457	MAP kinase-activated protein kinase 2	Homo sapiens		 50							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384560	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384560&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70681757	160863643		CHEMBL2036457				ZINC84711608	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936871	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccncc1	InChI=1S/C27H24ClN5O2/c28-21-3-1-19(2-4-21)24-9-10-25(34-24)26-31-35-27(20-11-13-29-14-12-20)33(26)23-7-5-22(6-8-23)32-17-15-30-16-18-32/h1-14,27,30H,15-18H2	DGKVORSMRTYOSA-UHFFFAOYSA-N	50384561	CHEMBL2036458	MAP kinase-activated protein kinase 2	Homo sapiens		 30							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692323	160863644		CHEMBL2036458				ZINC84668576	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936872	Fc1ccc(nc1)C1ON=C(N1c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(Cl)cc1	InChI=1S/C27H23ClFN5O2/c28-19-3-1-18(2-4-19)24-11-12-25(35-24)26-32-36-27(23-10-5-20(29)17-31-23)34(26)22-8-6-21(7-9-22)33-15-13-30-14-16-33/h1-12,17,27,30H,13-16H2	WGJIAMSLBTZDEA-UHFFFAOYSA-N	50384562	CHEMBL2036459	MAP kinase-activated protein kinase 2	Homo sapiens		 60							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384562&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683872	160863645		CHEMBL2036459				ZINC84655460	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936873	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1cncnc1	InChI=1S/C26H23ClN6O2/c27-20-3-1-18(2-4-20)23-9-10-24(34-23)25-31-35-26(19-15-29-17-30-16-19)33(25)22-7-5-21(6-8-22)32-13-11-28-12-14-32/h1-10,15-17,26,28H,11-14H2	UKHRSMGNALKRNZ-UHFFFAOYSA-N	50384563	CHEMBL2036461	MAP kinase-activated protein kinase 2	Homo sapiens		 70							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384563	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384563&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683873	160863646		CHEMBL2036461				ZINC84668602	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936874	Fc1ccc(cc1)C1ON=C(N1c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(Cl)cc1	InChI=1S/C28H24ClFN4O2/c29-21-5-1-19(2-6-21)25-13-14-26(35-25)27-32-36-28(20-3-7-22(30)8-4-20)34(27)24-11-9-23(10-12-24)33-17-15-31-16-18-33/h1-14,28,31H,15-18H2	XSJWMYWMOTWCAL-UHFFFAOYSA-N	50384564	CHEMBL2036598	MAP kinase-activated protein kinase 2	Homo sapiens		 160							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384564	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384564&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70681765	160863647		CHEMBL2036598				ZINC84723428	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936875	Fc1ccc(C2ON=C(N2c2ccc(cc2)N2CCNCC2)c2ccc(o2)-c2ccc(Cl)cc2)c(F)c1	InChI=1S/C28H23ClF2N4O2/c29-19-3-1-18(2-4-19)25-11-12-26(36-25)27-33-37-28(23-10-5-20(30)17-24(23)31)35(27)22-8-6-21(7-9-22)34-15-13-32-14-16-34/h1-12,17,28,32H,13-16H2	NQESPVWTXKDFFE-UHFFFAOYSA-N	50384565	CHEMBL2036599	MAP kinase-activated protein kinase 2	Homo sapiens		 100							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384565	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384565&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70686016	160863648		CHEMBL2036599				ZINC84723433	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936876	Fc1cc(F)cc(c1)C1ON=C(N1c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(Cl)cc1	InChI=1S/C28H23ClF2N4O2/c29-20-3-1-18(2-4-20)25-9-10-26(36-25)27-33-37-28(19-15-21(30)17-22(31)16-19)35(27)24-7-5-23(6-8-24)34-13-11-32-12-14-34/h1-10,15-17,28,32H,11-14H2	IOEWHUVVOHHRDF-UHFFFAOYSA-N	50384566	CHEMBL2036600	MAP kinase-activated protein kinase 2	Homo sapiens		 190							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384566	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384566&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70694393	160863649		CHEMBL2036600				ZINC84723441	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936877	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1cnc[nH]1	InChI=1S/C25H23ClN6O2/c26-18-3-1-17(2-4-18)22-9-10-23(33-22)24-30-34-25(21-15-28-16-29-21)32(24)20-7-5-19(6-8-20)31-13-11-27-12-14-31/h1-10,15-16,25,27H,11-14H2,(H,28,29)	KECNMIOXQSMLDW-UHFFFAOYSA-N	50384567	CHEMBL2036601	MAP kinase-activated protein kinase 2	Homo sapiens		 70							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384567&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692331	160863650		CHEMBL2036601				ZINC84729219	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936878	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1cnc(nc1)-c1ccccc1	InChI=1S/C32H27ClN6O2/c33-25-8-6-22(7-9-25)28-14-15-29(40-28)31-37-41-32(24-20-35-30(36-21-24)23-4-2-1-3-5-23)39(31)27-12-10-26(11-13-27)38-18-16-34-17-19-38/h1-15,20-21,32,34H,16-19H2	HANUVWPRANRHOJ-UHFFFAOYSA-N	50384568	CHEMBL2036602	MAP kinase-activated protein kinase 2	Homo sapiens		 1200							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384568	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384568&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683880	160863651		CHEMBL2036602				ZINC84710701	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936879	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccc(cc1)-c1ncccn1	InChI=1S/C32H27ClN6O2/c33-25-8-6-22(7-9-25)28-14-15-29(40-28)31-37-41-32(24-4-2-23(3-5-24)30-35-16-1-17-36-30)39(31)27-12-10-26(11-13-27)38-20-18-34-19-21-38/h1-17,32,34H,18-21H2	VMBVYIUKVXLQTB-UHFFFAOYSA-N	50384569	CHEMBL2036603	MAP kinase-activated protein kinase 2	Homo sapiens		 330							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384569	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384569&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683881	160863652		CHEMBL2036603				ZINC84710705	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936880	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccc(cc1)-c1cncnc1	InChI=1S/C32H27ClN6O2/c33-26-7-5-23(6-8-26)29-13-14-30(40-29)31-37-41-32(24-3-1-22(2-4-24)25-19-35-21-36-20-25)39(31)28-11-9-27(10-12-28)38-17-15-34-16-18-38/h1-14,19-21,32,34H,15-18H2	GIDNAZYCGIBNKS-UHFFFAOYSA-N	50384570	CHEMBL2036604	MAP kinase-activated protein kinase 2	Homo sapiens		 100							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384570&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70688146	160863653		CHEMBL2036604				ZINC84672508	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936881	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1cccc(c1)-c1cncnc1	InChI=1S/C32H27ClN6O2/c33-26-6-4-22(5-7-26)29-12-13-30(40-29)31-37-41-32(24-3-1-2-23(18-24)25-19-35-21-36-20-25)39(31)28-10-8-27(9-11-28)38-16-14-34-15-17-38/h1-13,18-21,32,34H,14-17H2	OLNMTGSIKLTZCY-UHFFFAOYSA-N	50384571	CHEMBL2036605	MAP kinase-activated protein kinase 2	Homo sapiens		 380							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384571	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384571&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70696464	160863654		CHEMBL2036605				ZINC84709048	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936882	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C32H27ClN6O2/c33-24-7-5-22(6-8-24)29-13-14-30(40-29)31-37-41-32(28-4-2-1-3-27(28)23-19-35-21-36-20-23)39(31)26-11-9-25(10-12-26)38-17-15-34-16-18-38/h1-14,19-21,32,34H,15-18H2	YCRNUCBVYJRPTD-UHFFFAOYSA-N	50384572	CHEMBL2036606	MAP kinase-activated protein kinase 2	Homo sapiens		 40							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384572&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70694394	160863655		CHEMBL2036606				ZINC84709052	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936883	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cccnc1	InChI=1S/C33H28ClN5O2/c34-25-9-7-23(8-10-25)30-15-16-31(40-30)32-37-41-33(29-6-2-1-5-28(29)24-4-3-17-36-22-24)39(32)27-13-11-26(12-14-27)38-20-18-35-19-21-38/h1-17,22,33,35H,18-21H2	DSIICHITQDHXRE-UHFFFAOYSA-N	50384573	CHEMBL2036607	MAP kinase-activated protein kinase 2	Homo sapiens		 180							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384573	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384573&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70690181	160863656		CHEMBL2036607				ZINC84711158	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936884	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1ccccc1	InChI=1S/C34H29ClN4O2/c35-26-12-10-25(11-13-26)31-18-19-32(40-31)33-37-41-34(30-9-5-4-8-29(30)24-6-2-1-3-7-24)39(33)28-16-14-27(15-17-28)38-22-20-36-21-23-38/h1-19,34,36H,20-23H2	HPLQQIPBTRZDSJ-UHFFFAOYSA-N	50384574	CHEMBL2036608	MAP kinase-activated protein kinase 2	Homo sapiens		 480							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384574	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384574&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683882	160863657		CHEMBL2036608				ZINC84653492	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936885	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccncn1	InChI=1S/C26H23ClN6O2/c27-19-3-1-18(2-4-19)23-9-10-24(34-23)25-31-35-26(22-11-12-29-17-30-22)33(25)21-7-5-20(6-8-21)32-15-13-28-14-16-32/h1-12,17,26,28H,13-16H2	DZJUCPPEXXLYJS-UHFFFAOYSA-N	50384575	CHEMBL2036460	MAP kinase-activated protein kinase 2	Homo sapiens		 60							ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384575	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384575&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70681758	160863658		CHEMBL2036460				ZINC84668600	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936886	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1	InChI=1S/C28H25ClN4O2/c29-22-8-6-20(7-9-22)25-14-15-26(34-25)27-31-35-28(21-4-2-1-3-5-21)33(27)24-12-10-23(11-13-24)32-18-16-30-17-19-32/h1-15,28,30H,16-19H2	ZWUWARMSLKVJAD-UHFFFAOYSA-N	50384555	CHEMBL2036452	MAP kinase-activated protein kinase 2	Homo sapiens				 6700					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384555	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384555&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70686009	160863638		CHEMBL2036452				ZINC84713172	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936887	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccn1	InChI=1S/C27H24ClN5O2/c28-20-6-4-19(5-7-20)24-12-13-25(34-24)26-31-35-27(23-3-1-2-14-30-23)33(26)22-10-8-21(9-11-22)32-17-15-29-16-18-32/h1-14,27,29H,15-18H2	CFHJAKKKDPAQLU-UHFFFAOYSA-N	50384559	CHEMBL2036456	MAP kinase-activated protein kinase 2	Homo sapiens				 3000					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384559	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384559&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692322	160863642		CHEMBL2036456				ZINC84711602	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936888	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccncc1	InChI=1S/C27H24ClN5O2/c28-21-3-1-19(2-4-21)24-9-10-25(34-24)26-31-35-27(20-11-13-29-14-12-20)33(26)23-7-5-22(6-8-23)32-17-15-30-16-18-32/h1-14,27,30H,15-18H2	DGKVORSMRTYOSA-UHFFFAOYSA-N	50384561	CHEMBL2036458	MAP kinase-activated protein kinase 2	Homo sapiens				 2700					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384561	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384561&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692323	160863644		CHEMBL2036458				ZINC84668576	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936889	Fc1ccc(nc1)C1ON=C(N1c1ccc(cc1)N1CCNCC1)c1ccc(o1)-c1ccc(Cl)cc1	InChI=1S/C27H23ClFN5O2/c28-19-3-1-18(2-4-19)24-11-12-25(35-24)26-32-36-27(23-10-5-20(29)17-31-23)34(26)22-8-6-21(7-9-22)33-15-13-30-14-16-33/h1-12,17,27,30H,13-16H2	WGJIAMSLBTZDEA-UHFFFAOYSA-N	50384562	CHEMBL2036459	MAP kinase-activated protein kinase 2	Homo sapiens				 3700					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384562	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384562&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683872	160863645		CHEMBL2036459				ZINC84655460	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936890	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1cnc[nH]1	InChI=1S/C25H23ClN6O2/c26-18-3-1-17(2-4-18)22-9-10-23(33-22)24-30-34-25(21-15-28-16-29-21)32(24)20-7-5-19(6-8-20)31-13-11-27-12-14-31/h1-10,15-16,25,27H,11-14H2,(H,28,29)	KECNMIOXQSMLDW-UHFFFAOYSA-N	50384567	CHEMBL2036601	MAP kinase-activated protein kinase 2	Homo sapiens				 2400					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384567	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384567&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70692331	160863650		CHEMBL2036601				ZINC84729219	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936891	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccc(cc1)-c1cncnc1	InChI=1S/C32H27ClN6O2/c33-26-7-5-23(6-8-26)29-13-14-30(40-29)31-37-41-32(24-3-1-22(2-4-24)25-19-35-21-36-20-25)39(31)28-11-9-27(10-12-28)38-17-15-34-16-18-38/h1-14,19-21,32,34H,15-18H2	GIDNAZYCGIBNKS-UHFFFAOYSA-N	50384570	CHEMBL2036604	MAP kinase-activated protein kinase 2	Homo sapiens				 820					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384570	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384570&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70688146	160863653		CHEMBL2036604				ZINC84672508	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936892	Clc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C32H27ClN6O2/c33-24-7-5-22(6-8-24)29-13-14-30(40-29)31-37-41-32(28-4-2-1-3-27(28)23-19-35-21-36-20-23)39(31)26-11-9-25(10-12-26)38-17-15-34-16-18-38/h1-14,19-21,32,34H,15-18H2	YCRNUCBVYJRPTD-UHFFFAOYSA-N	50384572	CHEMBL2036606	MAP kinase-activated protein kinase 2	Homo sapiens				 730					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384572	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384572&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70694394	160863655		CHEMBL2036606				ZINC84709052	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936893	Fc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C32H27FN6O2/c33-24-7-5-22(6-8-24)29-13-14-30(40-29)31-37-41-32(28-4-2-1-3-27(28)23-19-35-21-36-20-23)39(31)26-11-9-25(10-12-26)38-17-15-34-16-18-38/h1-14,19-21,32,34H,15-18H2	YMDHZMGPKRALSL-UHFFFAOYSA-N	50384544	CHEMBL2036610	MAP kinase-activated protein kinase 2	Homo sapiens				 760					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384544	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384544&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70683883	160863627		CHEMBL2036610				ZINC84653496	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936894	N#Cc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C33H27N7O2/c34-19-23-5-7-24(8-6-23)30-13-14-31(41-30)32-38-42-33(29-4-2-1-3-28(29)25-20-36-22-37-21-25)40(32)27-11-9-26(10-12-27)39-17-15-35-16-18-39/h1-14,20-22,33,35H,15-18H2	ZLCHYXMKVDHWGU-UHFFFAOYSA-N	50384542	CHEMBL2036616	MAP kinase-activated protein kinase 2	Homo sapiens				 1200					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384542&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57330141	160863625		CHEMBL2036616				ZINC84724597	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50936895	N#Cc1ccc(cc1)-c1ccc(o1)C1=NOC(N1c1ccc(cc1)N1CCNCC1)c1ccccc1-c1cncnc1	InChI=1S/C33H27N7O2/c34-19-23-5-7-24(8-6-23)30-13-14-31(41-30)32-38-42-33(29-4-2-1-3-28(29)25-20-36-22-37-21-25)40(32)27-11-9-26(10-12-27)39-17-15-35-16-18-39/h1-14,20-22,33,35H,15-18H2	ZLCHYXMKVDHWGU-UHFFFAOYSA-N	50384542	CHEMBL2036616	MAP kinase-activated protein kinase 2	Homo sapiens				 1200					ChEMBL	10.1021/ml200238g	10.7270/Q2K0759N	24900435			Qin, J; Dhondi, P; Huang, X; Aslanian, R; Fossetta, J; Tian, F; Lundell, D; Palani, A	TBA	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50384542	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50384542&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57330141	160863625		CHEMBL2036616				ZINC84724597	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963968	N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2nccc2n1	InChI=1S/C18H20ClFN6/c19-14-9-13(5-6-15(14)20)24-18-10-16(25-17-7-8-22-26(17)18)23-12-3-1-11(21)2-4-12/h5-12,24H,1-4,21H2,(H,23,25)/t11-,12-	ZDXQLMBSNKHXCJ-HAQNSBGRSA-N	50395262	CHEMBL2163999	MAP kinase-activated protein kinase 2	Homo sapiens	 6000								ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395262&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9907612	163344286		CHEMBL2163999				ZINC95555411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963969	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)nc2)C(=O)N1	InChI=1S/C21H18N4OS/c1-11-3-4-13(10-22-11)15-6-5-14-16(25-15)7-8-17-18(14)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1	CMWRPDHVGMHLSZ-GFCCVEGCSA-N	50395272	CHEMBL1231206	MAP kinase-activated protein kinase 2	Homo sapiens		 5							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395272&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B97	3FYJ,6T8X,7NRY	44631903	163344296		CHEMBL1231206	DB07430			ZINC39258365	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963970	Nc1nc2Oc3cc(O)c(O)cc3Cc2c(N)c1C#N	InChI=1S/C13H10N4O3/c14-4-7-11(15)6-1-5-2-8(18)9(19)3-10(5)20-13(6)17-12(7)16/h2-3,18-19H,1H2,(H4,15,16,17)	XIQLPJBFPQIUDK-UHFFFAOYSA-N	50225787	2,4-diamino-6,7-dihydroxy-10H-9-oxa-1-aza-anthracene-3-carbonitrile; TFA::CHEMBL1185204::CHEMBL397819	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50225787	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50225787&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9821424	104096860		CHEMBL1185204CHEMBL397819				ZINC28824806	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963972	CCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C20H26N6O/c1-3-27-17-8-6-15(7-9-17)24-20-14(2)19(23-16-5-4-11-21-13-16)25-18-10-12-22-26(18)20/h6-10,12,16,21,24H,3-5,11,13H2,1-2H3,(H,23,25)/t16-/m0/s1	WJOUGMPFYANZMI-INIZCTEOSA-N	50395274	CHEMBL1235213	MAP kinase-activated protein kinase 2	Homo sapiens		 11000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395274&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	PDY	3WBL,3A2C	49867482	163344298		CHEMBL1235213				ZINC58633578	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963973	Cc1nc2ccc(Nc3c(C)c(N[C@H]4CCCNC4)nc4ccnn34)cc2s1	InChI=1S/C20H23N7S/c1-12-19(24-15-4-3-8-21-11-15)26-18-7-9-22-27(18)20(12)25-14-5-6-16-17(10-14)28-13(2)23-16/h5-7,9-10,15,21,25H,3-4,8,11H2,1-2H3,(H,24,26)/t15-/m0/s1	MHAZFQTWVWWROD-HNNXBMFYSA-N	50395267	CHEMBL2163608	MAP kinase-activated protein kinase 2	Homo sapiens		 8400							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395267&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60201066	163344291		CHEMBL2163608				ZINC95554046	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963974	COCCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C21H28N6O2/c1-15-20(24-17-4-3-10-22-14-17)26-19-9-11-23-27(19)21(15)25-16-5-7-18(8-6-16)29-13-12-28-2/h5-9,11,17,22,25H,3-4,10,12-14H2,1-2H3,(H,24,26)/t17-/m0/s1	JPEZXBCEWYKFBS-KRWDZBQOSA-N	50395275	CHEMBL2163616	MAP kinase-activated protein kinase 2	Homo sapiens		 7600							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395275&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200737	163344299		CHEMBL2163616				ZINC95553584	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963975	CCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C20H26N6O/c1-3-27-17-8-6-15(7-9-17)24-20-14(2)19(23-16-5-4-11-21-13-16)25-18-10-12-22-26(18)20/h6-10,12,16,21,24H,3-5,11,13H2,1-2H3,(H,23,25)/t16-/m0/s1	WJOUGMPFYANZMI-INIZCTEOSA-N	50395274	CHEMBL1235213	MAP kinase-activated protein kinase 2	Homo sapiens		 7200							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395274&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	PDY	3WBL,3A2C	49867482	163344298		CHEMBL1235213				ZINC58633578	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963991	CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20?,26-,28+/m1/s1	HKSZLNNOFSGOKW-ZGQXJOJZSA-N	50059889	(staurosporine)3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::12-[3-methoxy-2,6-dimethyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::12-[3-methoxy-6-methyl-4-methylamino-(2S,3R,4R,6S)-tetrahydro-2H-2-pyranyl]-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::15,16-dimethoxy-15-methyl-17-methylamino-(15S)-4,14,20-triazaheptacyclo[12.12.2.02,6.07,28.08,13.020,27.021,26]octacosa-1(27),2(6),7(28),8(13),9,11,21(26),22,24-nonaen-3-one::2-Amino-4-(2-amino-2-phenyl-ethyl)-6-(2-hydroxy-phenyl)-nicotinonitrile::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one(Staurosporine)::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3R,4R,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-(2S,3S,4S,6R)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21,23,25-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-2-methyl-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14,19,21(26),22,24,27-nonaen-16-one::3-methoxy-4-methylamino-(2R,3S,4S,6S)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::3-methoxy-4-methylamino-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one,2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-::AM-2282::CHEMBL162::Indolocarbazole nitrogen derivative::Isoindolinone Urea derivative::staurosporin	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50059889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50059889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			44299148	103955664		CHEMBL162			C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963992	CCOc1ccc(Nc2c(C)c(N[C@@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C20H26N6O/c1-3-27-17-8-6-15(7-9-17)24-20-14(2)19(23-16-5-4-11-21-13-16)25-18-10-12-22-26(18)20/h6-10,12,16,21,24H,3-5,11,13H2,1-2H3,(H,23,25)/t16-/m1/s1	WJOUGMPFYANZMI-MRXNPFEDSA-N	50395263	CHEMBL2163604	MAP kinase-activated protein kinase 2	Homo sapiens		 1200							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395263&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200408	163344287		CHEMBL2163604				ZINC95552504	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963993	CCc1c(N[C@H]2CC[C@H](N)CC2)nc2ccnn2c1Nc1ccccc1Cl	InChI=1S/C20H25ClN6/c1-2-15-19(24-14-9-7-13(22)8-10-14)26-18-11-12-23-27(18)20(15)25-17-6-4-3-5-16(17)21/h3-6,11-14,25H,2,7-10,22H2,1H3,(H,24,26)/t13-,14-	GEGHZQQXQVCRQJ-HDJSIYSDSA-N	50395264	CHEMBL2163605	MAP kinase-activated protein kinase 2	Homo sapiens		 1500							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395264	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395264&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60201072	163344288		CHEMBL2163605				ZINC95556112	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963994	Cc1c(N[C@H]2CC[C@H](N)CC2)nc2ccnn2c1Nc1ccccc1Cl	InChI=1S/C19H23ClN6/c1-12-18(23-14-8-6-13(21)7-9-14)25-17-10-11-22-26(17)19(12)24-16-5-3-2-4-15(16)20/h2-5,10-11,13-14,24H,6-9,21H2,1H3,(H,23,25)/t13-,14-	DFFKHQMOSUXPAS-HDJSIYSDSA-N	50395265	CHEMBL2163606	MAP kinase-activated protein kinase 2	Homo sapiens		 1700							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395265	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395265&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60201070	163344289		CHEMBL2163606				ZINC95556412	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963995	N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccccc2Cl)n2nccc2n1	InChI=1S/C18H21ClN6/c19-14-3-1-2-4-15(14)23-18-11-16(24-17-9-10-21-25(17)18)22-13-7-5-12(20)6-8-13/h1-4,9-13,23H,5-8,20H2,(H,22,24)/t12-,13-	FISPOMCKBOYLEG-JOCQHMNTSA-N	50395266	CHEMBL2163607	MAP kinase-activated protein kinase 2	Homo sapiens		 200							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395266	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395266&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60201068	163344290		CHEMBL2163607				ZINC95554008	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963996	Cc1nc2ccc(Nc3c(C)c(N[C@H]4CCCNC4)nc4ccnn34)cc2s1	InChI=1S/C20H23N7S/c1-12-19(24-15-4-3-8-21-11-15)26-18-7-9-22-27(18)20(12)25-14-5-6-16-17(10-14)28-13(2)23-16/h5-7,9-10,15,21,25H,3-4,8,11H2,1-2H3,(H,24,26)/t15-/m0/s1	MHAZFQTWVWWROD-HNNXBMFYSA-N	50395267	CHEMBL2163608	MAP kinase-activated protein kinase 2	Homo sapiens		 54							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395267	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395267&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60201066	163344291		CHEMBL2163608				ZINC95554046	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963997	Cc1c(N[C@H]2CCCNC2)nc2ccnn2c1Nc1ccc2n(C)ncc2c1	InChI=1S/C20H24N8/c1-13-19(24-16-4-3-8-21-12-16)26-18-7-9-22-28(18)20(13)25-15-5-6-17-14(10-15)11-23-27(17)2/h5-7,9-11,16,21,25H,3-4,8,12H2,1-2H3,(H,24,26)/t16-/m0/s1	DMBVYCDISNAJPU-INIZCTEOSA-N	50395268	CHEMBL2163611	MAP kinase-activated protein kinase 2	Homo sapiens		 76							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395268	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395268&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200906	163344292		CHEMBL2163611				ZINC95553143	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963998	CC(=O)c1ccc(s1)-c1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C24H26N6OS/c1-15-23(27-19-4-3-12-25-14-19)29-22-11-13-26-30(22)24(15)28-18-7-5-17(6-8-18)21-10-9-20(32-21)16(2)31/h5-11,13,19,25,28H,3-4,12,14H2,1-2H3,(H,27,29)/t19-/m0/s1	LCYDFIUWKWJIDS-IBGZPJMESA-N	50395269	CHEMBL2163610	MAP kinase-activated protein kinase 2	Homo sapiens		 57							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395269	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395269&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200904	163344293		CHEMBL2163610				ZINC95553670	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50963999	Cc1c(N[C@H]2CCCNC2)nc2ccnn2c1Nc1ccc(cc1)C(=O)NC1CCCC1	InChI=1S/C24H31N7O/c1-16-22(27-20-7-4-13-25-15-20)30-21-12-14-26-31(21)23(16)28-19-10-8-17(9-11-19)24(32)29-18-5-2-3-6-18/h8-12,14,18,20,25,28H,2-7,13,15H2,1H3,(H,27,30)(H,29,32)/t20-/m0/s1	NSKVOJSVXKFYHW-FQEVSTJZSA-N	50395270	CHEMBL2163609	MAP kinase-activated protein kinase 2	Homo sapiens		 140							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395270	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395270&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200902	163344294		CHEMBL2163609				ZINC95553972	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964000	Cc1c(N[C@H]2CCCNC2)nc2ccnn2c1Nc1ccc(OCCN2CCOCC2)cc1	InChI=1S/C24H33N7O2/c1-18-23(27-20-3-2-9-25-17-20)29-22-8-10-26-31(22)24(18)28-19-4-6-21(7-5-19)33-16-13-30-11-14-32-15-12-30/h4-8,10,20,25,28H,2-3,9,11-17H2,1H3,(H,27,29)/t20-/m0/s1	LYSVMDJSAMSOKD-FQEVSTJZSA-N	50395271	CHEMBL2163612	MAP kinase-activated protein kinase 2	Homo sapiens		 160							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395271	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395271&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200900	163344295		CHEMBL2163612				ZINC95553201	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964001	COCCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C21H28N6O2/c1-15-20(24-17-4-3-10-22-14-17)26-19-9-11-23-27(19)21(15)25-16-5-7-18(8-6-16)29-13-12-28-2/h5-9,11,17,22,25H,3-4,10,12-14H2,1-2H3,(H,24,26)/t17-/m0/s1	JPEZXBCEWYKFBS-KRWDZBQOSA-N	50395275	CHEMBL2163616	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395275	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395275&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200737	163344299		CHEMBL2163616				ZINC95553584	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964002	CCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C20H26N6O/c1-3-27-17-8-6-15(7-9-17)24-20-14(2)19(23-16-5-4-11-21-13-16)25-18-10-12-22-26(18)20/h6-10,12,16,21,24H,3-5,11,13H2,1-2H3,(H,23,25)/t16-/m0/s1	WJOUGMPFYANZMI-INIZCTEOSA-N	50395274	CHEMBL1235213	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395274	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395274&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	PDY	3WBL,3A2C	49867482	163344298		CHEMBL1235213				ZINC58633578	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964003	Cc1c(N[C@H]2CC[C@H](N)CC2)nc2ccnn2c1Nc1cccc(OCc2ccccc2)c1	InChI=1S/C26H30N6O/c1-18-25(29-21-12-10-20(27)11-13-21)31-24-14-15-28-32(24)26(18)30-22-8-5-9-23(16-22)33-17-19-6-3-2-4-7-19/h2-9,14-16,20-21,30H,10-13,17,27H2,1H3,(H,29,31)/t20-,21-	PBNSIICXVJCCNA-MEMLXQNLSA-N	50395286	CHEMBL2163615	MAP kinase-activated protein kinase 2	Homo sapiens		 3000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395286	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395286&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200736	163344310		CHEMBL2163615				ZINC95553213	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964004	CCOC(=O)c1cccc(Nc2c(C)c(N[C@H]3CC[C@H](N)CC3)nc3ccnn23)c1	InChI=1S/C22H28N6O2/c1-3-30-22(29)15-5-4-6-18(13-15)26-21-14(2)20(27-19-11-12-24-28(19)21)25-17-9-7-16(23)8-10-17/h4-6,11-13,16-17,26H,3,7-10,23H2,1-2H3,(H,25,27)/t16-,17-	JRYNLODJMAKSHC-QAQDUYKDSA-N	50395287	CHEMBL2163614	MAP kinase-activated protein kinase 2	Homo sapiens		 1900							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395287	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395287&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200572	163344311		CHEMBL2163614				ZINC95556093	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964005	CCOc1cccc(Nc2c(C)c(N[C@H]3CC[C@H](N)CC3)nc3ccnn23)c1	InChI=1S/C21H28N6O/c1-3-28-18-6-4-5-17(13-18)25-21-14(2)20(26-19-11-12-23-27(19)21)24-16-9-7-15(22)8-10-16/h4-6,11-13,15-16,25H,3,7-10,22H2,1-2H3,(H,24,26)/t15-,16-	QNBSVVQYYNTNTN-WKILWMFISA-N	50395288	CHEMBL2163613	MAP kinase-activated protein kinase 2	Homo sapiens		 1400							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395288	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395288&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200571	163344312		CHEMBL2163613				ZINC95555040	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964006	Cc1c(N[C@H]2CC[C@H](N)CC2)nc2ccnn2c1Nc1ccc(OCc2ccccc2)cc1	InChI=1S/C26H30N6O/c1-18-25(29-21-9-7-20(27)8-10-21)31-24-15-16-28-32(24)26(18)30-22-11-13-23(14-12-22)33-17-19-5-3-2-4-6-19/h2-6,11-16,20-21,30H,7-10,17,27H2,1H3,(H,29,31)/t20-,21-	GCZMDRRRHDHAKX-MEMLXQNLSA-N	50395289	CHEMBL2163617	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395289	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395289&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200570	163344313		CHEMBL2163617				ZINC95556858	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964007	CCOC(=O)c1ccc(Nc2c(C)c(N[C@H]3CC[C@H](N)CC3)nc3ccnn23)cc1	InChI=1S/C22H28N6O2/c1-3-30-22(29)15-4-8-18(9-5-15)26-21-14(2)20(27-19-12-13-24-28(19)21)25-17-10-6-16(23)7-11-17/h4-5,8-9,12-13,16-17,26H,3,6-7,10-11,23H2,1-2H3,(H,25,27)/t16-,17-	HKASKRDXOJLTOA-QAQDUYKDSA-N	50395290	CHEMBL2163618	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395290	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395290&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200569	163344314		CHEMBL2163618				ZINC95553650	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964008	N[C@H]1CC[C@@H](CC1)Nc1cc(NCc2ccccc2)n2nccc2n1	InChI=1S/C19H24N6/c20-15-6-8-16(9-7-15)23-17-12-19(25-18(24-17)10-11-22-25)21-13-14-4-2-1-3-5-14/h1-5,10-12,15-16,21H,6-9,13,20H2,(H,23,24)/t15-,16-	QWQBUHHFXHTFDX-WKILWMFISA-N	50395291	CHEMBL2163619	MAP kinase-activated protein kinase 2	Homo sapiens		 7000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395291	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395291&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71460534	163344315		CHEMBL2163619				ZINC95555733	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964009	N[C@H]1CC[C@@H](CC1)Nc1cc(NCC2CCCCC2)n2nccc2n1	InChI=1S/C19H30N6/c20-15-6-8-16(9-7-15)23-17-12-19(25-18(24-17)10-11-22-25)21-13-14-4-2-1-3-5-14/h10-12,14-16,21H,1-9,13,20H2,(H,23,24)/t15-,16-	FPYUGZDITUVTSF-WKILWMFISA-N	50395292	CHEMBL2163620	MAP kinase-activated protein kinase 2	Homo sapiens		 11000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395292	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395292&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71462243	163344316		CHEMBL2163620				ZINC95554651	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964010	CC(C)CCNc1cc(N[C@H]2CC[C@H](N)CC2)nc2ccnn12	InChI=1S/C17H28N6/c1-12(2)7-9-19-17-11-15(22-16-8-10-20-23(16)17)21-14-5-3-13(18)4-6-14/h8,10-14,19H,3-7,9,18H2,1-2H3,(H,21,22)/t13-,14-	CVVSJBKXLVKCAB-HDJSIYSDSA-N	50395293	CHEMBL2163621	MAP kinase-activated protein kinase 2	Homo sapiens		 12000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395293	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395293&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71453355	163344317		CHEMBL2163621				ZINC95557105	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964011	CN(c1ccc(F)c(Cl)c1)c1cc(N[C@H]2CC[C@H](N)CC2)nc2ccnn12	InChI=1S/C19H22ClFN6/c1-26(14-6-7-16(21)15(20)10-14)19-11-17(25-18-8-9-23-27(18)19)24-13-4-2-12(22)3-5-13/h6-13H,2-5,22H2,1H3,(H,24,25)/t12-,13-	DFVNKDHSOKOSSE-JOCQHMNTSA-N	50395294	CHEMBL2163622	MAP kinase-activated protein kinase 2	Homo sapiens		>300000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395294	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395294&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200406	163344318		CHEMBL2163622				ZINC95553178	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964012	CCc1c(NC2CCCNC2)nc2ccnn2c1Nc1ccc(F)c(Cl)c1	InChI=1S/C19H22ClFN6/c1-2-14-18(24-13-4-3-8-22-11-13)26-17-7-9-23-27(17)19(14)25-12-5-6-16(21)15(20)10-12/h5-7,9-10,13,22,25H,2-4,8,11H2,1H3,(H,24,26)	JABUMBYVIQWISU-UHFFFAOYSA-N	50395276	CHEMBL2163623	MAP kinase-activated protein kinase 2	Homo sapiens		 700							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395276	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395276&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10430386	163344300		CHEMBL2163623				ZINC38836337	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964013	Cc1c(NC2CCCNC2)nc2ccnn2c1Nc1ccc(F)c(Cl)c1	InChI=1S/C18H20ClFN6/c1-11-17(23-13-3-2-7-21-10-13)25-16-6-8-22-26(16)18(11)24-12-4-5-15(20)14(19)9-12/h4-6,8-9,13,21,24H,2-3,7,10H2,1H3,(H,23,25)	CKAYFBSKGOPXBW-UHFFFAOYSA-N	50395277	CHEMBL2163624	MAP kinase-activated protein kinase 2	Homo sapiens		 510							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395277	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395277&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200403	163344301		CHEMBL2163624				ZINC95553245	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964014	CCOc1ccc(Nc2c(C)c(O[C@H]3CC[C@H](N)CC3)nc3ccnn23)cc1	InChI=1S/C21H27N5O2/c1-3-27-17-10-6-16(7-11-17)24-20-14(2)21(25-19-12-13-23-26(19)20)28-18-8-4-15(22)5-9-18/h6-7,10-13,15,18,24H,3-5,8-9,22H2,1-2H3/t15-,18-	OGBIZPXCOXJIAZ-RZDIXWSQSA-N	50395295	CHEMBL2163625	MAP kinase-activated protein kinase 2	Homo sapiens		 570							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395295	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395295&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			45485213	163344319		CHEMBL2163625				ZINC43104295	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964015	CCOc1ccc(Nc2c(C)c(N[C@H]3CCCNC3=O)nc3ccnn23)cc1	InChI=1S/C20H24N6O2/c1-3-28-15-8-6-14(7-9-15)23-19-13(2)18(25-17-10-12-22-26(17)19)24-16-5-4-11-21-20(16)27/h6-10,12,16,23H,3-5,11H2,1-2H3,(H,21,27)(H,24,25)/t16-/m0/s1	RDMUJEKAQCETGY-INIZCTEOSA-N	50395296	CHEMBL2163626	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395296	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395296&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71462244	163344320		CHEMBL2163626				ZINC95554673	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964016	CCOc1ccc(Nc2c(C)c(nc3ccnn23)N(C)C2CCCNC2)cc1	InChI=1S/C21H28N6O/c1-4-28-18-9-7-16(8-10-18)24-21-15(2)20(25-19-11-13-23-27(19)21)26(3)17-6-5-12-22-14-17/h7-11,13,17,22,24H,4-6,12,14H2,1-3H3	MQDBEPPETPSXJD-UHFFFAOYSA-N	50395297	CHEMBL2163627	MAP kinase-activated protein kinase 2	Homo sapiens		 26000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395297	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395297&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57753017	163344321		CHEMBL2163627				ZINC95556762	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964017	CCOc1ccc(Nc2c(C)c(N[C@@H]3CCCNC3)nc3ccnn23)cc1	InChI=1S/C20H26N6O/c1-3-27-17-8-6-15(7-9-17)24-20-14(2)19(23-16-5-4-11-21-13-16)25-18-10-12-22-26(18)20/h6-10,12,16,21,24H,3-5,11,13H2,1-2H3,(H,23,25)/t16-/m1/s1	WJOUGMPFYANZMI-MRXNPFEDSA-N	50395263	CHEMBL2163604	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395263	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395263&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200408	163344287		CHEMBL2163604				ZINC95552504	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964018	CCOc1ccc(Nc2c(C)c(NCCO)nc3ccnn23)cc1	InChI=1S/C17H21N5O2/c1-3-24-14-6-4-13(5-7-14)20-17-12(2)16(18-10-11-23)21-15-8-9-19-22(15)17/h4-9,20,23H,3,10-11H2,1-2H3,(H,18,21)	PTSIWXULRIUVKW-UHFFFAOYSA-N	50395298	CHEMBL2163977	MAP kinase-activated protein kinase 2	Homo sapiens		 83000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395298	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395298&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200255	163344322		CHEMBL2163977				ZINC95552915	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964019	CCOc1ccc(Nc2c(C)c(NCCCCN)nc3ccnn23)cc1	InChI=1S/C19H26N6O/c1-3-26-16-8-6-15(7-9-16)23-19-14(2)18(21-12-5-4-11-20)24-17-10-13-22-25(17)19/h6-10,13,23H,3-5,11-12,20H2,1-2H3,(H,21,24)	ZLMZJHJVSYIKCF-UHFFFAOYSA-N	50395299	CHEMBL2163353	MAP kinase-activated protein kinase 2	Homo sapiens		 4100							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395299	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395299&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200254	163344323		CHEMBL2163353				ZINC95556416	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964020	CCOc1ccc(Nc2c(C)c(NCCCN)nc3ccnn23)cc1	InChI=1S/C18H24N6O/c1-3-25-15-7-5-14(6-8-15)22-18-13(2)17(20-11-4-10-19)23-16-9-12-21-24(16)18/h5-9,12,22H,3-4,10-11,19H2,1-2H3,(H,20,23)	OIPIROSCRJXFJE-UHFFFAOYSA-N	50395300	CHEMBL2163978	MAP kinase-activated protein kinase 2	Homo sapiens		 8700							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395300	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395300&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200253	163344324		CHEMBL2163978				ZINC95553249	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964021	CCOc1ccc(Nc2c(C)c(NCCN)nc3ccnn23)cc1	InChI=1S/C17H22N6O/c1-3-24-14-6-4-13(5-7-14)21-17-12(2)16(19-11-9-18)22-15-8-10-20-23(15)17/h4-8,10,21H,3,9,11,18H2,1-2H3,(H,19,22)	WORGLDYCNXLSNH-UHFFFAOYSA-N	50395301	CHEMBL2163979	MAP kinase-activated protein kinase 2	Homo sapiens		 2500							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395301	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395301&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200252	163344325		CHEMBL2163979				ZINC95552213	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964022	CCOc1ccc(Nc2c(C)c(N[C@H]3CC[C@H](O)CC3)nc3ccnn23)cc1	InChI=1S/C21H27N5O2/c1-3-28-18-10-6-16(7-11-18)24-21-14(2)20(25-19-12-13-22-26(19)21)23-15-4-8-17(27)9-5-15/h6-7,10-13,15,17,24,27H,3-5,8-9H2,1-2H3,(H,23,25)/t15-,17-	SZUYWYQWZNHPCP-JCNLHEQBSA-N	50395302	CHEMBL2163980	MAP kinase-activated protein kinase 2	Homo sapiens		 89000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395302	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395302&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200105	163344326		CHEMBL2163980				ZINC95556128	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964023	CCOc1ccc(Nc2c(C)c(N[C@H]3CC[C@H](N)CC3)nc3ccnn23)cc1	InChI=1S/C21H28N6O/c1-3-28-18-10-8-17(9-11-18)25-21-14(2)20(26-19-12-13-23-27(19)21)24-16-6-4-15(22)5-7-16/h8-13,15-16,25H,3-7,22H2,1-2H3,(H,24,26)/t15-,16-	IWCDYFKDQHUZMN-WKILWMFISA-N	50395303	CHEMBL2163981	MAP kinase-activated protein kinase 2	Homo sapiens		 360							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395303	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395303&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10339752	163344327		CHEMBL2163981				ZINC38557234	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964024	Fc1ccc(Nc2cc(NCC3CCNCC3)nc3ccnn23)cc1Cl	InChI=1S/C18H20ClFN6/c19-14-9-13(1-2-15(14)20)24-18-10-16(25-17-5-8-23-26(17)18)22-11-12-3-6-21-7-4-12/h1-2,5,8-10,12,21,24H,3-4,6-7,11H2,(H,22,25)	IUSULHYDGWZKNL-UHFFFAOYSA-N	50395304	CHEMBL2163982	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395304&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200099	163344328		CHEMBL2163982				ZINC95557500	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964025	Nc1ccc(Nc2cc(Nc3ccc(F)c(Cl)c3)n3nccc3n2)cc1	InChI=1S/C18H14ClFN6/c19-14-9-13(5-6-15(14)20)24-18-10-16(25-17-7-8-22-26(17)18)23-12-3-1-11(21)2-4-12/h1-10,24H,21H2,(H,23,25)	IQBZALSULYGYIS-UHFFFAOYSA-N	50395305	CHEMBL2163983	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395305&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200098	163344329		CHEMBL2163983				ZINC95555373	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964026	Fc1ccc(Nc2cc(NC3CCCNC3)nc3ccnn23)cc1Cl	InChI=1S/C17H18ClFN6/c18-13-8-11(3-4-14(13)19)23-17-9-15(22-12-2-1-6-20-10-12)24-16-5-7-21-25(16)17/h3-5,7-9,12,20,23H,1-2,6,10H2,(H,22,24)	DQHGXHGUNOSYSE-UHFFFAOYSA-N	50395278	CHEMBL2163984	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395278	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395278&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60200097	163344302		CHEMBL2163984				ZINC95552606	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964027	Fc1ccc(Nc2cc(NC3CCNCC3)nc3ccnn23)cc1Cl	InChI=1S/C17H18ClFN6/c18-13-9-12(1-2-14(13)19)23-17-10-15(22-11-3-6-20-7-4-11)24-16-5-8-21-25(16)17/h1-2,5,8-11,20,23H,3-4,6-7H2,(H,22,24)	KVMQLIWHVZKJPV-UHFFFAOYSA-N	50395306	CHEMBL2163985	MAP kinase-activated protein kinase 2	Homo sapiens		 25000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395306	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395306&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199942	163344330		CHEMBL2163985				ZINC95554664	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964028	NC1CCCC(C1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2nccc2n1	InChI=1S/C18H20ClFN6/c19-14-9-13(4-5-15(14)20)24-18-10-16(25-17-6-7-22-26(17)18)23-12-3-1-2-11(21)8-12/h4-7,9-12,24H,1-3,8,21H2,(H,23,25)	JOMIQNQAGMOXQZ-UHFFFAOYSA-N	50395307	CHEMBL2163986	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395307	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395307&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199940	163344331		CHEMBL2163986				ZINC95556837	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964029	CC(=O)N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2nccc2n1	InChI=1S/C20H22ClFN6O/c1-12(29)24-13-2-4-14(5-3-13)25-18-11-20(28-19(27-18)8-9-23-28)26-15-6-7-17(22)16(21)10-15/h6-11,13-14,26H,2-5H2,1H3,(H,24,29)(H,25,27)/t13-,14-	LQQLWOIHCSEMRP-HDJSIYSDSA-N	50395308	CHEMBL2163987	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395308	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395308&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199938	163344332		CHEMBL2163987				ZINC95554044	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964030	CCN(CC)[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2nccc2n1	InChI=1S/C22H28ClFN6/c1-3-29(4-2)17-8-5-15(6-9-17)26-20-14-22(30-21(28-20)11-12-25-30)27-16-7-10-19(24)18(23)13-16/h7,10-15,17,27H,3-6,8-9H2,1-2H3,(H,26,28)/t15-,17-	OLSYNVUMGPILJG-JCNLHEQBSA-N	50395309	CHEMBL2163988	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395309	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395309&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199934	163344333		CHEMBL2163988				ZINC95557537	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964031	CCN[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2nccc2n1	InChI=1S/C20H24ClFN6/c1-2-23-13-3-5-14(6-4-13)25-18-12-20(28-19(27-18)9-10-24-28)26-15-7-8-17(22)16(21)11-15/h7-14,23,26H,2-6H2,1H3,(H,25,27)/t13-,14-	KECJUZXONYNDMK-HDJSIYSDSA-N	50395310	CHEMBL2163989	MAP kinase-activated protein kinase 2	Homo sapiens		 2000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395310	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395310&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199933	163344334		CHEMBL2163989				ZINC95552148	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964032	Fc1ccc(Nc2cc(NC3CCCCC3)nc3ccnn23)cc1Cl	InChI=1S/C18H19ClFN5/c19-14-10-13(6-7-15(14)20)23-18-11-16(22-12-4-2-1-3-5-12)24-17-8-9-21-25(17)18/h6-12,23H,1-5H2,(H,22,24)	BLECGOGNNZTYRZ-UHFFFAOYSA-N	50395311	CHEMBL2163990	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395311	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395311&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199775	163344335		CHEMBL2163990				ZINC95553284	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964033	N[C@H]1CC[C@@H](CC1)Nc1nc2ccnn2c(Nc2ccc(F)c(Cl)c2)c1-c1ccccc1	InChI=1S/C24H24ClFN6/c25-19-14-18(10-11-20(19)26)30-24-22(15-4-2-1-3-5-15)23(31-21-12-13-28-32(21)24)29-17-8-6-16(27)7-9-17/h1-5,10-14,16-17,30H,6-9,27H2,(H,29,31)/t16-,17-	DVBJHZDVRNGXLE-QAQDUYKDSA-N	50395279	CHEMBL2163991	MAP kinase-activated protein kinase 2	Homo sapiens		 1600							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395279	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395279&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10049465	163344303		CHEMBL2163991				ZINC95555374	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964034	CCCc1c(N[C@H]2CC[C@H](N)CC2)nc2ccnn2c1Nc1ccc(F)c(Cl)c1	InChI=1S/C21H26ClFN6/c1-2-3-16-20(26-14-6-4-13(24)5-7-14)28-19-10-11-25-29(19)21(16)27-15-8-9-18(23)17(22)12-15/h8-14,27H,2-7,24H2,1H3,(H,26,28)/t13-,14-	VOEASXDMGAGUCL-HDJSIYSDSA-N	50395280	CHEMBL2163992	MAP kinase-activated protein kinase 2	Homo sapiens		 600							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395280	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395280&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9979332	163344304		CHEMBL2163992				ZINC95552819	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964035	CCc1c(N[C@H]2CC[C@H](N)CC2)nc2ccnn2c1Nc1ccc(F)c(Cl)c1	InChI=1S/C20H24ClFN6/c1-2-15-19(25-13-5-3-12(23)4-6-13)27-18-9-10-24-28(18)20(15)26-14-7-8-17(22)16(21)11-14/h7-13,26H,2-6,23H2,1H3,(H,25,27)/t12-,13-	KCTYPUKDSRNILF-JOCQHMNTSA-N	50395281	CHEMBL2163993	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395281	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395281&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10092544	163344305		CHEMBL2163993				ZINC95555761	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964036	Cc1c(N[C@H]2CC[C@H](N)CC2)nc2ccnn2c1Nc1ccc(F)c(Cl)c1	InChI=1S/C19H22ClFN6/c1-11-18(24-13-4-2-12(22)3-5-13)26-17-8-9-23-27(17)19(11)25-14-6-7-16(21)15(20)10-14/h6-10,12-13,25H,2-5,22H2,1H3,(H,24,26)/t12-,13-	RVONHYLJCYPGQH-JOCQHMNTSA-N	50395282	CHEMBL2163994	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395282	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395282&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10430385	163344306		CHEMBL2163994				ZINC03987090	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964037	N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2ncc(Br)c2n1	InChI=1S/C18H19BrClFN6/c19-13-9-23-27-17(25-12-5-6-15(21)14(20)7-12)8-16(26-18(13)27)24-11-3-1-10(22)2-4-11/h5-11,25H,1-4,22H2,(H,24,26)/t10-,11-	CYNLHOIMJSFAKV-XYPYZODXSA-N	50395283	CHEMBL2163995	MAP kinase-activated protein kinase 2	Homo sapiens		 9200							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395283	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395283&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10456600	163344307		CHEMBL2163995				ZINC38909032	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964038	N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2ncc(Cl)c2n1	InChI=1S/C18H19Cl2FN6/c19-13-7-12(5-6-15(13)21)25-17-8-16(24-11-3-1-10(22)2-4-11)26-18-14(20)9-23-27(17)18/h5-11,25H,1-4,22H2,(H,24,26)/t10-,11-	AOSKHAXBGHJEBD-XYPYZODXSA-N	50395284	CHEMBL2163996	MAP kinase-activated protein kinase 2	Homo sapiens		 8100							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395284	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395284&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10001536	163344308		CHEMBL2163996				ZINC95556422	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964039	N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2ncc(C#N)c2n1	InChI=1S/C19H19ClFN7/c20-15-7-14(5-6-16(15)21)26-18-8-17(25-13-3-1-12(23)2-4-13)27-19-11(9-22)10-24-28(18)19/h5-8,10,12-13,26H,1-4,23H2,(H,25,27)/t12-,13-	NYDFVFWQQZXRJN-JOCQHMNTSA-N	50395285	CHEMBL2163997	MAP kinase-activated protein kinase 2	Homo sapiens		 3100							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395285	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395285&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			10250350	163344309		CHEMBL2163997				ZINC38426830	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964040	CC(C)(C)c1cc2nc(N[C@H]3CC[C@H](N)CC3)cc(Nc3ccc(F)c(Cl)c3)n2n1	InChI=1S/C22H28ClFN6/c1-22(2,3)18-11-20-28-19(26-14-6-4-13(25)5-7-14)12-21(30(20)29-18)27-15-8-9-17(24)16(23)10-15/h8-14,27H,4-7,25H2,1-3H3,(H,26,28)/t13-,14-	GITBSUCZKZDBQU-HDJSIYSDSA-N	50395312	CHEMBL2163998	MAP kinase-activated protein kinase 2	Homo sapiens		>300000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395312	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395312&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199605	163344336		CHEMBL2163998				ZINC95554311	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964041	Cc1cc2nc(N[C@H]3CC[C@H](N)CC3)cc(Nc3ccc(F)c(Cl)c3)n2n1	InChI=1S/C19H22ClFN6/c1-11-8-18-25-17(23-13-4-2-12(22)3-5-13)10-19(27(18)26-11)24-14-6-7-16(21)15(20)9-14/h6-10,12-13,24H,2-5,22H2,1H3,(H,23,25)/t12-,13-	UZFSNHVYEFHDBN-JOCQHMNTSA-N	50395313	CHEMBL2164000	MAP kinase-activated protein kinase 2	Homo sapiens		>300000							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395313	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395313&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60199603	163344337		CHEMBL2164000				ZINC95555323	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50964042	N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2nccc2n1	InChI=1S/C18H20ClFN6/c19-14-9-13(5-6-15(14)20)24-18-10-16(25-17-7-8-22-26(17)18)23-12-3-1-11(21)2-4-12/h5-12,24H,1-4,21H2,(H,23,25)/t11-,12-	ZDXQLMBSNKHXCJ-HAQNSBGRSA-N	50395262	CHEMBL2163999	MAP kinase-activated protein kinase 2	Homo sapiens		 1300							ChEMBL	10.1021/jm300411k	10.7270/Q20K29PX	22746295			Kosugi, T; Mitchell, DR; Fujino, A; Imai, M; Kambe, M; Kobayashi, S; Makino, H; Matsueda, Y; Oue, Y; Komatsu, K; Imaizumi, K; Sakai, Y; Sugiura, S; Takenouchi, O; Unoki, G; Yamakoshi, Y; Cunliffe, V; Frearson, J; Gordon, R; Harris, CJ; Kalloo-Hosein, H; Le, J; Patel, G; Simpson, DJ; Sherborne, B; Thomas, PS; Suzuki, N; Takimoto-Kamimura, M; Kataoka, K	Teijin Pharma Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395262	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395262&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			9907612	163344286		CHEMBL2163999				ZINC95555411	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51082188	CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(no2)C(=O)NC2CCN(CC2)C2CCC3(CC2)OCCO3)cc1	InChI=1S/C31H38N4O7/c1-34(2)21-3-5-24(6-4-21)41-27-18-23(36)17-26(37)29(27)28-19-25(33-42-28)30(38)32-20-9-13-35(14-10-20)22-7-11-31(12-8-22)39-15-16-40-31/h3-6,17-20,22,36-37H,7-16H2,1-2H3,(H,32,38)	DPZWKZQIGWCTDT-UHFFFAOYSA-N	50442757	CHEMBL2443026	MAP kinase-activated protein kinase 2	Homo sapiens		>10.0							ChEMBL	10.1016/j.bmc.2013.09.018	10.7270/Q2V989HZ	24100158			Brasca, MG; Mantegani, S; Amboldi, N; Bindi, S; Caronni, D; Casale, E; Ceccarelli, W; Colombo, N; De Ponti, A; Donati, D; Ermoli, A; Fachin, G; Felder, ER; Ferguson, RD; Fiorelli, C; Guanci, M; Isacchi, A; Pesenti, E; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Fogliatto, G	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442757	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442757&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			72696079	175455074		CHEMBL2443026				ZINC68247155	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51082189	CC(C)Nc1ccc(Oc2cc(O)cc(O)c2-c2cc(no2)C(=O)NC2CCN(C)CC2)cc1	InChI=1S/C25H30N4O5/c1-15(2)26-16-4-6-19(7-5-16)33-22-13-18(30)12-21(31)24(22)23-14-20(28-34-23)25(32)27-17-8-10-29(3)11-9-17/h4-7,12-15,17,26,30-31H,8-11H2,1-3H3,(H,27,32)	PFINYWQVHGQFKS-UHFFFAOYSA-N	50442758	CHEMBL2443139	MAP kinase-activated protein kinase 2	Homo sapiens		>10.0							ChEMBL	10.1016/j.bmc.2013.09.018	10.7270/Q2V989HZ	24100158			Brasca, MG; Mantegani, S; Amboldi, N; Bindi, S; Caronni, D; Casale, E; Ceccarelli, W; Colombo, N; De Ponti, A; Donati, D; Ermoli, A; Fachin, G; Felder, ER; Ferguson, RD; Fiorelli, C; Guanci, M; Isacchi, A; Pesenti, E; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Fogliatto, G	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442758	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442758&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			73346589	175455075		CHEMBL2443139				ZINC96286428	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51082190	CN(C)c1ccc(Oc2cc(O)cc(O)c2-c2cc(no2)C(=O)NC2CCN(C)CC2)cc1	InChI=1S/C24H28N4O5/c1-27(2)16-4-6-18(7-5-16)32-21-13-17(29)12-20(30)23(21)22-14-19(26-33-22)24(31)25-15-8-10-28(3)11-9-15/h4-7,12-15,29-30H,8-11H2,1-3H3,(H,25,31)	VUOFPKJWKCCHBI-UHFFFAOYSA-N	50442759	CHEMBL2443138	MAP kinase-activated protein kinase 2	Homo sapiens		>10.0							ChEMBL	10.1016/j.bmc.2013.09.018	10.7270/Q2V989HZ	24100158			Brasca, MG; Mantegani, S; Amboldi, N; Bindi, S; Caronni, D; Casale, E; Ceccarelli, W; Colombo, N; De Ponti, A; Donati, D; Ermoli, A; Fachin, G; Felder, ER; Ferguson, RD; Fiorelli, C; Guanci, M; Isacchi, A; Pesenti, E; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Fogliatto, G	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442759&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49782469	175455076		CHEMBL2443138				ZINC68247151	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51082191	CN1CCC(CC1)NC(=O)c1cc(on1)-c1c(O)cc(O)cc1Oc1ccc(cc1)[N+]([O-])=O	InChI=1S/C22H22N4O7/c1-25-8-6-13(7-9-25)23-22(29)17-12-20(33-24-17)21-18(28)10-15(27)11-19(21)32-16-4-2-14(3-5-16)26(30)31/h2-5,10-13,27-28H,6-9H2,1H3,(H,23,29)	YLQODGGPIHWTHR-UHFFFAOYSA-N	50442760	CHEMBL2443044	MAP kinase-activated protein kinase 2	Homo sapiens		>10.0							ChEMBL	10.1016/j.bmc.2013.09.018	10.7270/Q2V989HZ	24100158			Brasca, MG; Mantegani, S; Amboldi, N; Bindi, S; Caronni, D; Casale, E; Ceccarelli, W; Colombo, N; De Ponti, A; Donati, D; Ermoli, A; Fachin, G; Felder, ER; Ferguson, RD; Fiorelli, C; Guanci, M; Isacchi, A; Pesenti, E; Polucci, P; Riceputi, L; Sola, F; Visco, C; Zuccotto, F; Fogliatto, G	Nerviano Medical Sciences srl	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50442760	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50442760&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	9UN	4B7P	49782688	175455077		CHEMBL2443044				ZINC95921417	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50974789	CN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)n(C4CCCC4)c3n2)cc1	InChI=1S/C27H32N8/c1-33-15-17-34(18-16-33)22-13-11-21(12-14-22)29-26-28-19-24-25(32-26)35(23-9-5-6-10-23)27(31-24)30-20-7-3-2-4-8-20/h2-4,7-8,11-14,19,23H,5-6,9-10,15-18H2,1H3,(H,30,31)(H,28,29,32)	QPOURHROVVCOHC-UHFFFAOYSA-N	50399676	CHEMBL2178352::US9096601, 8-26	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm301365e	10.7270/Q2251KBV	23116168			Yang, J; Wang, LJ; Liu, JJ; Zhong, L; Zheng, RL; Xu, Y; Ji, P; Zhang, CH; Wang, WJ; Lin, XD; Li, LL; Wei, YQ; Yang, SY	Sichuan University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50399676	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50399676&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	7XR	5X2C,5X27	54760383	163348700		CHEMBL2178352				ZINC95580356	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043130	Clc1ccc(Cl)c(CNc2ncc(C(=O)NCCCN3CCOC3=O)c(NC3CCCC3)n2)c1	InChI=1S/C23H28Cl2N6O3/c24-16-6-7-19(25)15(12-16)13-27-22-28-14-18(20(30-22)29-17-4-1-2-5-17)21(32)26-8-3-9-31-10-11-34-23(31)33/h6-7,12,14,17H,1-5,8-11,13H2,(H,26,32)(H2,27,28,29,30)	XYASHXPUZJDWIO-UHFFFAOYSA-N	50425829	CHEMBL2312304	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2012.12.013	10.7270/Q26D5V9W	23312472			Powell, NA; Hoffman, JK; Ciske, FL; Kaufman, MD; Kohrt, JT; Quin, J; Sheehan, DJ; Delaney, A; Baxi, SM; Catana, C; McConnell, P; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425829&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	V5W	7OAI	71552942	164154704		CHEMBL2312304				ZINC95596939	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043131	Clc1ccc(Cl)c(CNc2ncc(C(=O)NCCCN3CCCC3=O)c(NC3CCCC3)n2)c1	InChI=1S/C24H30Cl2N6O2/c25-17-8-9-20(26)16(13-17)14-28-24-29-15-19(22(31-24)30-18-5-1-2-6-18)23(34)27-10-4-12-32-11-3-7-21(32)33/h8-9,13,15,18H,1-7,10-12,14H2,(H,27,34)(H2,28,29,30,31)	VDKBGBCLPKTOGS-UHFFFAOYSA-N	50425830	CHEMBL2312303	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2012.12.013	10.7270/Q26D5V9W	23312472			Powell, NA; Hoffman, JK; Ciske, FL; Kaufman, MD; Kohrt, JT; Quin, J; Sheehan, DJ; Delaney, A; Baxi, SM; Catana, C; McConnell, P; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425830&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71552941	164154705		CHEMBL2312303				ZINC95593995	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043132	COc1ccccc1CNc1ncc(C(=O)NCCCN2CCCC2=O)c(NC2CCCC2)n1	InChI=1S/C25H34N6O3/c1-34-21-11-5-2-8-18(21)16-27-25-28-17-20(23(30-25)29-19-9-3-4-10-19)24(33)26-13-7-15-31-14-6-12-22(31)32/h2,5,8,11,17,19H,3-4,6-7,9-10,12-16H2,1H3,(H,26,33)(H2,27,28,29,30)	ZXZLVQGNVOKCAS-UHFFFAOYSA-N	50425831	CHEMBL2312301	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2012.12.013	10.7270/Q26D5V9W	23312472			Powell, NA; Hoffman, JK; Ciske, FL; Kaufman, MD; Kohrt, JT; Quin, J; Sheehan, DJ; Delaney, A; Baxi, SM; Catana, C; McConnell, P; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425831&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	14S	4FF8	70789756	164154706		CHEMBL2312301				ZINC95597132	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043133	COc1ccc(CCNc2ncc(C(=O)NCCCN3CCCC3=O)c(NC3CCCC3)n2)cc1OC	InChI=1S/C27H38N6O4/c1-36-22-11-10-19(17-23(22)37-2)12-14-29-27-30-18-21(25(32-27)31-20-7-3-4-8-20)26(35)28-13-6-16-33-15-5-9-24(33)34/h10-11,17-18,20H,3-9,12-16H2,1-2H3,(H,28,35)(H2,29,30,31,32)	BQICBFKSXAVIBF-UHFFFAOYSA-N	50425832	CHEMBL2312290	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.bmcl.2012.12.013	10.7270/Q26D5V9W	23312472			Powell, NA; Hoffman, JK; Ciske, FL; Kaufman, MD; Kohrt, JT; Quin, J; Sheehan, DJ; Delaney, A; Baxi, SM; Catana, C; McConnell, P; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425832&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71552696	164154707		CHEMBL2312290				ZINC95595019	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51054204	Cc1c(F)c(ccc1C(=O)N1CCOc2ccc(cc2C1)-c1ccc(N)nc1)S(C)(=O)=O	InChI=1S/C23H22FN3O4S/c1-14-18(5-7-20(22(14)24)32(2,29)30)23(28)27-9-10-31-19-6-3-15(11-17(19)13-27)16-4-8-21(25)26-12-16/h3-8,11-12H,9-10,13H2,1-2H3,(H2,25,26)	LNFBAYSBVQBKFR-UHFFFAOYSA-N	50429867	CHEMBL2333365	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/jm3007933	10.7270/Q2ZC847X	23394126			Takeuchi, CS; Kim, BG; Blazey, CM; Ma, S; Johnson, HW; Anand, NK; Arcalas, A; Baik, TG; Buhr, CA; Cannoy, J; Epshteyn, S; Joshi, A; Lara, K; Lee, MS; Wang, L; Leahy, JW; Nuss, JM; Aay, N; Aoyama, R; Foster, P; Lee, J; Lehoux, I; Munagala, N; Plonowski, A; Rajan, S; Woolfrey, J; Yamaguchi, K; Lamb, P; Miller, N	Exelixis Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50429867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50429867&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			59604787	164158742		CHEMBL2333365				ZINC95550928	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043235	CN(C)C1CCC(CC1)Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cc(C)no1	InChI=1S/C22H26Cl2N6O/c1-13-8-20(31-29-13)19-12-25-22(27-17-10-14(23)9-15(24)11-17)28-21(19)26-16-4-6-18(7-5-16)30(2)3/h8-12,16,18H,4-7H2,1-3H3,(H2,25,26,27,28)	ZTSOUDMNSOYCTG-UHFFFAOYSA-N	50425862	CHEMBL2312654	MAP kinase-activated protein kinase 2	Homo sapiens		 18570							ChEMBL	10.1016/j.bmcl.2012.12.028	10.7270/Q2XW4M38	23312943			Powell, NA; Hoffman, JK; Ciske, FL; Kohrt, JT; Baxi, SM; Peng, YW; Zhong, M; Catana, C; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425862&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71553154	164154737		CHEMBL2312654				ZINC95598090	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043236	CN1CCC(CC1)NC(=O)c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1N[C@@H]1COC[C@H]1O	InChI=1S/C21H26Cl2N6O3/c1-29-4-2-14(3-5-29)25-20(31)16-9-24-21(26-15-7-12(22)6-13(23)8-15)28-19(16)27-17-10-32-11-18(17)30/h6-9,14,17-18,30H,2-5,10-11H2,1H3,(H,25,31)(H2,24,26,27,28)/t17-,18-/m1/s1	PIKLKDCPFVVYDK-QZTJIDSGSA-N	50425863	CHEMBL2312652	MAP kinase-activated protein kinase 2	Homo sapiens		 30000							ChEMBL	10.1016/j.bmcl.2012.12.028	10.7270/Q2XW4M38	23312943			Powell, NA; Hoffman, JK; Ciske, FL; Kohrt, JT; Baxi, SM; Peng, YW; Zhong, M; Catana, C; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425863&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71553152	164154738		CHEMBL2312652				ZINC95598372	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043237	CN(C)C1CCC(CC1)Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1C(=O)NC1CCN(C)CC1	InChI=1S/C25H35Cl2N7O/c1-33(2)21-6-4-18(5-7-21)29-23-22(24(35)30-19-8-10-34(3)11-9-19)15-28-25(32-23)31-20-13-16(26)12-17(27)14-20/h12-15,18-19,21H,4-11H2,1-3H3,(H,30,35)(H2,28,29,31,32)	SQKBBDOFPPNVCL-UHFFFAOYSA-N	50425864	CHEMBL2312649	MAP kinase-activated protein kinase 2	Homo sapiens		 30000							ChEMBL	10.1016/j.bmcl.2012.12.028	10.7270/Q2XW4M38	23312943			Powell, NA; Hoffman, JK; Ciske, FL; Kohrt, JT; Baxi, SM; Peng, YW; Zhong, M; Catana, C; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425864&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71553085	164154739		CHEMBL2312649				ZINC95593559	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043238	CN1CCC(CC1)NC(=O)c1cnc(NCc2cc(Cl)ccc2Cl)nc1NC1CCCC1	InChI=1S/C23H30Cl2N6O/c1-31-10-8-18(9-11-31)29-22(32)19-14-27-23(30-21(19)28-17-4-2-3-5-17)26-13-15-12-16(24)6-7-20(15)25/h6-7,12,14,17-18H,2-5,8-11,13H2,1H3,(H,29,32)(H2,26,27,28,30)	PRAFFLMXUBGHGX-UHFFFAOYSA-N	50425865	CHEMBL2312646	MAP kinase-activated protein kinase 2	Homo sapiens		 30000							ChEMBL	10.1016/j.bmcl.2012.12.028	10.7270/Q2XW4M38	23312943			Powell, NA; Hoffman, JK; Ciske, FL; Kohrt, JT; Baxi, SM; Peng, YW; Zhong, M; Catana, C; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425865&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71553012	164154740		CHEMBL2312646				ZINC95593503	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51043239	COc1ccccc1CNc1ncc(C(=O)NC2CCN(C)CC2)c(NC2CCCC2)n1	InChI=1S/C24H34N6O2/c1-30-13-11-19(12-14-30)28-23(31)20-16-26-24(29-22(20)27-18-8-4-5-9-18)25-15-17-7-3-6-10-21(17)32-2/h3,6-7,10,16,18-19H,4-5,8-9,11-15H2,1-2H3,(H,28,31)(H2,25,26,27,29)	IHJZXCJKSRQJCM-UHFFFAOYSA-N	50425861	CHEMBL2312645	MAP kinase-activated protein kinase 2	Homo sapiens		 30000							ChEMBL	10.1016/j.bmcl.2012.12.028	10.7270/Q2XW4M38	23312943			Powell, NA; Hoffman, JK; Ciske, FL; Kohrt, JT; Baxi, SM; Peng, YW; Zhong, M; Catana, C; Ohren, J; Perrin, LA; Edmunds, JJ	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50425861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50425861&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71553011	164154736		CHEMBL2312645				ZINC95594199	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51004498	Oc1ccc(NC(=O)CCCc2ccc(cc2)-c2ccccc2F)cc1	InChI=1S/C22H20FNO2/c23-21-6-2-1-5-20(21)17-10-8-16(9-11-17)4-3-7-22(26)24-18-12-14-19(25)15-13-18/h1-2,5-6,8-15,25H,3-4,7H2,(H,24,26)	ODYAQBDIXCVKAE-UHFFFAOYSA-N	50411445	CHEMBL235658	MAP kinase-activated protein kinase 2	Homo sapiens	 330								ChEMBL	10.1016/j.bmcl.2007.10.036	10.7270/Q2W095P4	17964780			Davis, T; Bagley, MC; Dix, MC; Murziani, PG; Rokicki, MJ; Widdowson, CS; Zayed, JM; Bachler, MA; Kipling, D	Cardiff University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50411445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50411445&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			11382492	163360469		CHEMBL235658				ZINC07992846	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000390	NC1=C(C#N)C(=N)CC2Oc3ccc(O)cc3CC12	InChI=1S/C14H13N3O2/c15-6-10-11(16)5-13-9(14(10)17)4-7-3-8(18)1-2-12(7)19-13/h1-3,9,13,16,18H,4-5,17H2	PJOMLFPVVDPQMV-UHFFFAOYSA-N	50162627	1,3-Diamino-7-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180959	MAP kinase-activated protein kinase 2	Homo sapiens		 25400							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162627	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162627&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936682	104048785		CHEMBL180959				ZINC34804504	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000391	COc1cc2CC3C(CC(=N)C(C#N)=C3N)Oc2cc1OC	InChI=1S/C16H17N3O3/c1-20-14-4-8-3-9-13(22-12(8)6-15(14)21-2)5-11(18)10(7-17)16(9)19/h4,6,9,13,18H,3,5,19H2,1-2H3	VVVYJVDWAJHXEB-UHFFFAOYSA-N	50162632	1,3-Diamino-6,7-dimethoxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL182090	MAP kinase-activated protein kinase 2	Homo sapiens		 64800							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162632	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162632&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936687	104048790		CHEMBL182090				ZINC34804376	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000392	CCOc1cc2OC3CC(=N)C(C#N)=C(N)C3Cc2cc1O	InChI=1S/C16H17N3O3/c1-2-21-15-6-13-8(4-12(15)20)3-9-14(22-13)5-11(18)10(7-17)16(9)19/h4,6,9,14,18,20H,2-3,5,19H2,1H3	JNUOMCNGLYMZLA-UHFFFAOYSA-N	50162633	1,3-Diamino-6-ethoxy-7-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL360764	MAP kinase-activated protein kinase 2	Homo sapiens		 9400							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162633	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162633&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936688	104048791		CHEMBL360764				ZINC34804329	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000393	NC1=C(C#N)C(=N)CC2Oc3cc(OCN4CCCC4)ccc3CC12	InChI=1S/C19H22N4O2/c20-10-15-16(21)9-18-14(19(15)22)7-12-3-4-13(8-17(12)25-18)24-11-23-5-1-2-6-23/h3-4,8,14,18,21H,1-2,5-7,9,11,22H2	VYKFPPSJVIFFTC-UHFFFAOYSA-N	50162635	1,3-Diamino-6-(pyrrolidin-1-ylmethoxy)-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180510	MAP kinase-activated protein kinase 2	Homo sapiens		 2910							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162635	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162635&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936690	104048793		CHEMBL180510				ZINC34804528	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000394	NC1=C(C#N)C(=N)CC2Oc3cc(O)cc(O)c3CC12	InChI=1S/C14H13N3O3/c15-5-9-10(16)4-13-8(14(9)17)3-7-11(19)1-6(18)2-12(7)20-13/h1-2,8,13,16,18-19H,3-4,17H2	FZKBQQASNIQQIE-UHFFFAOYSA-N	50162636	1,3-Diamino-6,8-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL360551	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162636	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162636&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936691	104048794		CHEMBL360551				ZINC34804319	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000395	NC1=C(C#N)C(=N)CC2Oc3ccccc3CC12	InChI=1S/C14H13N3O/c15-7-10-11(16)6-13-9(14(10)17)5-8-3-1-2-4-12(8)18-13/h1-4,9,13,16H,5-6,17H2	QFGYTMRQASRUDP-UHFFFAOYSA-N	50162639	1,3-Diamino-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180054	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162639	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162639&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936694	104048797		CHEMBL180054				ZINC34804339	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000396	NC1=C(C#N)C(=N)CC2Oc3c(CC12)ccc(O)c3O	InChI=1S/C14H13N3O3/c15-5-8-9(16)4-11-7(12(8)17)3-6-1-2-10(18)13(19)14(6)20-11/h1-2,7,11,16,18-19H,3-4,17H2	NEMMVEATRRXURO-UHFFFAOYSA-N	50162638	1,3-Diamino-5,6-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180362	MAP kinase-activated protein kinase 2	Homo sapiens		 6920							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162638	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162638&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936693	104048796		CHEMBL180362				ZINC34804417	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000397	NC1=C(C#N)C(=N)CC2Oc3c(O)cccc3CC12	InChI=1S/C14H13N3O2/c15-6-9-10(16)5-12-8(13(9)17)4-7-2-1-3-11(18)14(7)19-12/h1-3,8,12,16,18H,4-5,17H2	MXZDHJJEZKVATA-UHFFFAOYSA-N	50162641	1,3-Diamino-5-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL182091	MAP kinase-activated protein kinase 2	Homo sapiens		 7120							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162641	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162641&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936696	104048799		CHEMBL182091				ZINC34804387	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000398	NC1=C(C#N)C(=N)CC2Oc3cc(O)c(O)cc3CC12	InChI=1S/C14H13N3O3/c15-5-8-9(16)3-13-7(14(8)17)1-6-2-10(18)11(19)4-12(6)20-13/h2,4,7,13,16,18-19H,1,3,17H2	PREPNWXJQOKJTB-UHFFFAOYSA-N	50162634	1,3-Diamino-6,7-dihydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL181212	MAP kinase-activated protein kinase 2	Homo sapiens		 920							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162634&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936689	104048792		CHEMBL181212				ZINC34804430	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000399	NC1=C(C#N)C(=N)CC2Oc3cc4OCCOc4cc3CC12	InChI=1S/C16H15N3O3/c17-7-10-11(18)5-13-9(16(10)19)3-8-4-14-15(6-12(8)22-13)21-2-1-20-14/h4,6,9,13,18H,1-3,5,19H2	RJQQQHQJELURRA-UHFFFAOYSA-N	50162646	8,10-Diamino-2,3,10a,11-tetrahydro-6aH-1,4,6-trioxa-naphthacene-9-carbonitrile::CHEMBL181069	MAP kinase-activated protein kinase 2	Homo sapiens		 55700							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162646	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162646&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936699	104048804		CHEMBL181069				ZINC34804351	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000400	NC1=C(C#N)C(=N)CC2Oc3ccc(N)cc3CC12	InChI=1S/C14H14N4O/c15-6-10-11(17)5-13-9(14(10)18)4-7-3-8(16)1-2-12(7)19-13/h1-3,9,13,17H,4-5,16,18H2	SAAJAIYEZJEWQD-UHFFFAOYSA-N	50162648	1,3,7-Triamino-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL180884	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162648	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162648&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936701	104048806		CHEMBL180884				ZINC34804403	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000401	NC1=C(C#N)C(=N)CC2Oc3cc(C4COCCO4)c(O)cc3CC12	InChI=1S/C18H19N3O4/c19-7-12-13(20)6-16-11(18(12)21)3-9-4-14(22)10(5-15(9)25-16)17-8-23-1-2-24-17/h4-5,11,16-17,20,22H,1-3,6,8,21H2	WGBIXNYWULDFON-UHFFFAOYSA-N	50162637	1,3-Diamino-6-[1,4]dioxan-2-yl-7-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL178413	MAP kinase-activated protein kinase 2	Homo sapiens		 11900							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162637	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162637&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936692	104048795		CHEMBL178413				ZINC34804308	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51000402	NC1=C(C#N)C(=N)CC2Oc3cc(O)ccc3CC12	InChI=1S/C14H13N3O2/c15-6-10-11(16)5-13-9(14(10)17)3-7-1-2-8(18)4-12(7)19-13/h1-2,4,9,13,16,18H,3,5,17H2	DQVHGTZZFYOEQW-UHFFFAOYSA-N	50162653	1,3-Diamino-6-hydroxy-9,9a-dihydro-4aH-xanthene-2-carbonitrile::CHEMBL361425	MAP kinase-activated protein kinase 2	Homo sapiens		 1080							ChEMBL	10.1016/j.bmcl.2005.01.067	10.7270/Q2PC31WT	15745802			Anderson, DR; Hegde, S; Reinhard, E; Gomez, L; Vernier, WF; Lee, L; Liu, S; Sambandam, A; Snider, PA; Masih, L	Pfizer Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50162653	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50162653&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			91936705	104048811		CHEMBL361425				ZINC34804492	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063157	N[C@H]1CC[C@@H](CC1)Nc1cnc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1	InChI=1S/C19H21ClN6O/c20-12-3-1-11(2-4-12)16-10-26-18(25-16)15(9-23-19(26)17(22)27)24-14-7-5-13(21)6-8-14/h1-4,9-10,13-14,24H,5-8,21H2,(H2,22,27)/t13-,14-	DJXPMLBJIXXVFI-HDJSIYSDSA-N	50433762	CHEMBL2381612	MAP kinase-activated protein kinase 2	Homo sapiens		 1980							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433762	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433762&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71614497	175446079		CHEMBL2381612				ZINC96269916	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063158	NC(=O)c1ncc(N[C@H]2CCCNC2)c2nc(cn12)-c1ccc(Cl)cc1	InChI=1S/C18H19ClN6O/c19-12-5-3-11(4-6-12)15-10-25-17(24-15)14(9-22-18(25)16(20)26)23-13-2-1-7-21-8-13/h3-6,9-10,13,21,23H,1-2,7-8H2,(H2,20,26)/t13-/m0/s1	VUQDZGWRLHHYTB-ZDUSSCGKSA-N	50433763	CHEMBL2381611	MAP kinase-activated protein kinase 2	Homo sapiens		 840							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433763	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433763&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	1KO	4JIK	72188683	175446080		CHEMBL2381611				ZINC95920753	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063159	N[C@H]1CC[C@@H](CC1)Nc1ncc(C(N)=O)c2nc(cn12)-c1ccc(Cl)cc1	InChI=1S/C19H21ClN6O/c20-12-3-1-11(2-4-12)16-10-26-18(25-16)15(17(22)27)9-23-19(26)24-14-7-5-13(21)6-8-14/h1-4,9-10,13-14H,5-8,21H2,(H2,22,27)(H,23,24)/t13-,14-	LJIBANXVQNPFQL-HDJSIYSDSA-N	50433764	CHEMBL2381607	MAP kinase-activated protein kinase 2	Homo sapiens		 4000							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433764	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433764&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71614291	175446081		CHEMBL2381607				ZINC96269917	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063160	NC(=O)c1cnc(N[C@H]2CCCNC2)c2nc(cn12)-c1ccc(F)cc1	InChI=1S/C18H19FN6O/c19-12-5-3-11(4-6-12)14-10-25-15(16(20)26)9-22-17(18(25)24-14)23-13-2-1-7-21-8-13/h3-6,9-10,13,21H,1-2,7-8H2,(H2,20,26)(H,22,23)/t13-/m0/s1	BCBAEHQTYTYENT-ZDUSSCGKSA-N	50433765	CHEMBL2381605	MAP kinase-activated protein kinase 2	Homo sapiens		 910							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433765	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433765&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863195	175446082		CHEMBL2381605				ZINC96269918	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063161	NC(=O)c1cnc(N[C@H]2CCCNC2)c2nc(cn12)-c1ccc2ccccc2c1	InChI=1S/C22H22N6O/c23-20(29)19-12-25-21(26-17-6-3-9-24-11-17)22-27-18(13-28(19)22)16-8-7-14-4-1-2-5-15(14)10-16/h1-2,4-5,7-8,10,12-13,17,24H,3,6,9,11H2,(H2,23,29)(H,25,26)/t17-/m0/s1	JKFQIDJSSIINNY-KRWDZBQOSA-N	50433766	CHEMBL2381604	MAP kinase-activated protein kinase 2	Homo sapiens		 910							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433766&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863552	175446083		CHEMBL2381604				ZINC96269919	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063162	N[C@H]1CC[C@@H](CC1)Nc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)c(Cl)c1	InChI=1S/C19H20Cl2N6O/c20-13-6-1-10(7-14(13)21)15-9-27-16(17(23)28)8-24-18(19(27)26-15)25-12-4-2-11(22)3-5-12/h1,6-9,11-12H,2-5,22H2,(H2,23,28)(H,24,25)/t11-,12-	CXIYFBKPJSQXDU-HAQNSBGRSA-N	50433767	CHEMBL2381603	MAP kinase-activated protein kinase 2	Homo sapiens		 820							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433767	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433767&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863436	175446084		CHEMBL2381603				ZINC96269920	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063163	N[C@H]1CC[C@H](CC1)Nc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1	InChI=1S/C19H21ClN6O/c20-12-3-1-11(2-4-12)15-10-26-16(17(22)27)9-23-18(19(26)25-15)24-14-7-5-13(21)6-8-14/h1-4,9-10,13-14H,5-8,21H2,(H2,22,27)(H,23,24)/t13-,14+	DIVVQJIIRBQSMU-OKILXGFUSA-N	50433768	CHEMBL2381602	MAP kinase-activated protein kinase 2	Homo sapiens		 1900							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433768	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433768&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863083	175446085		CHEMBL2381602					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063164	N[C@H]1CC[C@@H](CC1)Nc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1	InChI=1S/C19H21ClN6O/c20-12-3-1-11(2-4-12)15-10-26-16(17(22)27)9-23-18(19(26)25-15)24-14-7-5-13(21)6-8-14/h1-4,9-10,13-14H,5-8,21H2,(H2,22,27)(H,23,24)/t13-,14-	DIVVQJIIRBQSMU-HDJSIYSDSA-N	50433761	CHEMBL2381601	MAP kinase-activated protein kinase 2	Homo sapiens		 60							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433761&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863083	175446078		CHEMBL2381601				ZINC96269915	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063165	CN[C@H]1CC[C@@H](CC1)Nc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1	InChI=1S/C20H23ClN6O/c1-23-14-6-8-15(9-7-14)25-19-20-26-16(12-2-4-13(21)5-3-12)11-27(20)17(10-24-19)18(22)28/h2-5,10-11,14-15,23H,6-9H2,1H3,(H2,22,28)(H,24,25)/t14-,15-	NVNJXYOVWGMPAO-SHTZXODSSA-N	50433769	CHEMBL2381600	MAP kinase-activated protein kinase 2	Homo sapiens		 400							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433769&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863435	175446086		CHEMBL2381600				ZINC96269921	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063166	NCCCNc1ncc(C(N)=O)n2cc(nc12)-c1ccc(Cl)cc1	InChI=1S/C16H17ClN6O/c17-11-4-2-10(3-5-11)12-9-23-13(14(19)24)8-21-15(16(23)22-12)20-7-1-6-18/h2-5,8-9H,1,6-7,18H2,(H2,19,24)(H,20,21)	KMDZJODRFCWAPG-UHFFFAOYSA-N	50433760	CHEMBL2381599	MAP kinase-activated protein kinase 2	Homo sapiens		 4090							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433760	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433760&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863317	175446077		CHEMBL2381599				ZINC96269914	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063167	NC(=O)c1cnc(NC2CCNCC2)c2nc(cn12)-c1ccc(Cl)cc1	InChI=1S/C18H19ClN6O/c19-12-3-1-11(2-4-12)14-10-25-15(16(20)26)9-22-17(18(25)24-14)23-13-5-7-21-8-6-13/h1-4,9-10,13,21H,5-8H2,(H2,20,26)(H,22,23)	UIBANLKKSQACJD-UHFFFAOYSA-N	50433759	CHEMBL2381598	MAP kinase-activated protein kinase 2	Homo sapiens		 4150							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433759&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863199	175446076		CHEMBL2381598				ZINC96269913	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063168	NC(=O)c1cnc(Nc2cccnc2)c2nc(cn12)-c1ccc(Cl)cc1	InChI=1S/C18H13ClN6O/c19-12-5-3-11(4-6-12)14-10-25-15(16(20)26)9-22-17(18(25)24-14)23-13-2-1-7-21-8-13/h1-10H,(H2,20,26)(H,22,23)	LXWWMTCZURVURW-UHFFFAOYSA-N	50433770	CHEMBL2381597	MAP kinase-activated protein kinase 2	Homo sapiens		 10000							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433770&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46863197	175446087		CHEMBL2381597				ZINC96269922	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51063169	NC(=O)c1cnc(N[C@H]2CCCNC2)c2nc(cn12)-c1ccc(Cl)cc1	InChI=1S/C18H19ClN6O/c19-12-5-3-11(4-6-12)14-10-25-15(16(20)26)9-22-17(18(25)24-14)23-13-2-1-7-21-8-13/h3-6,9-10,13,21H,1-2,7-8H2,(H2,20,26)(H,22,23)/t13-/m0/s1	KJDMOEPAJHJNBM-ZDUSSCGKSA-N	50433758	CHEMBL2381596	MAP kinase-activated protein kinase 2	Homo sapiens		 650							ChEMBL	10.1016/j.bmcl.2013.03.100	10.7270/Q2Z60QFW	23587425			Meng, Z; Ciavarri, JP; McRiner, A; Zhao, Y; Zhao, L; Reddy, PA; Zhang, X; Fischmann, TO; Whitehurst, C; Arshad Siddiqui, M	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50433758	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50433758&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57752723	175446075		CHEMBL2381596				ZINC96269912	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064482	CCN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C23H24ClN3O2/c1-2-27(20-9-7-19(8-10-20)26-15-13-25-14-16-26)23(28)22-12-11-21(29-22)17-3-5-18(24)6-4-17/h3-12,25H,2,13-16H2,1H3	ZQXYAXCRCBTDIH-UHFFFAOYSA-N	50380305	CHEMBL2017459	MAP kinase-activated protein kinase 2	Homo sapiens		 130							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380305	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380305&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70695898	160859388		CHEMBL2017459				ZINC84596616	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064483	CN(C(=O)c1ccc(o1)-c1ccc(Cl)cc1)c1ccc(cc1)N1CCNCC1	InChI=1S/C22H22ClN3O2/c1-25(18-6-8-19(9-7-18)26-14-12-24-13-15-26)22(27)21-11-10-20(28-21)16-2-4-17(23)5-3-16/h2-11,24H,12-15H2,1H3	VVLMVMQNQKVXTF-UHFFFAOYSA-N	50380304	CHEMBL2017458	MAP kinase-activated protein kinase 2	Homo sapiens		 600							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50380304	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50380304&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			70689583	160859387		CHEMBL2017458				ZINC84635931	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064484	Clc1ccc(cc1)-c1ccc(o1)C(=O)Nc1ccc(cc1)N1CCNCC1	InChI=1S/C21H20ClN3O2/c22-16-3-1-15(2-4-16)19-9-10-20(27-19)21(26)24-17-5-7-18(8-6-17)25-13-11-23-12-14-25/h1-10,23H,11-14H2,(H,24,26)	CAIGVNVLJGDZSF-UHFFFAOYSA-N	50362169	CHEMBL1938680	MAP kinase-activated protein kinase 2	Homo sapiens		 5000							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362169	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362169&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			57401151	136966231		CHEMBL1938680				ZINC73224553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064501	O=C1N(Cc2ccccc2-c2cncnc2)c2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C34H28N6O2/c35-18-23-5-7-24(8-6-23)32-17-27-15-26-16-29(39-13-11-36-12-14-39)9-10-31(26)40(34(41)33(27)42-32)21-25-3-1-2-4-30(25)28-19-37-22-38-20-28/h1-10,16-17,19-20,22,36H,11-15,21H2	LEXOCJKTBRIGNK-UHFFFAOYSA-N	50434486	CHEMBL2385548	MAP kinase-activated protein kinase 2	Homo sapiens				 138					ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434486&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53235497	175446803		CHEMBL2385548				ZINC72314980	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064502	FC1(F)c2cc(oc2C(=O)N(Cc2ccccc2-c2cncnc2)c2ccc(cc12)C1CCNCC1)-c1ccc(cc1)C#N	InChI=1S/C35H27F2N5O2/c36-35(37)29-15-25(23-11-13-39-14-12-23)9-10-31(29)42(20-26-3-1-2-4-28(26)27-18-40-21-41-19-27)34(43)33-30(35)16-32(44-33)24-7-5-22(17-38)6-8-24/h1-10,15-16,18-19,21,23,39H,11-14,20H2	OBUSIIKBWCHMIA-UHFFFAOYSA-N	50434487	CHEMBL2385550	MAP kinase-activated protein kinase 2	Homo sapiens		 8.9							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434487&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625684	175446804		CHEMBL2385550				ZINC96270542	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064503	O=C1N(Cc2ccccc2-c2cncnc2)c2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)C1CCNCC1	InChI=1S/C35H29N5O2/c36-18-23-5-7-25(8-6-23)33-17-29-16-28-15-26(24-11-13-37-14-12-24)9-10-32(28)40(35(41)34(29)42-33)21-27-3-1-2-4-31(27)30-19-38-22-39-20-30/h1-10,15,17,19-20,22,24,37H,11-14,16,21H2	BILSXWZYSWWEFT-UHFFFAOYSA-N	50434488	CHEMBL2385549	MAP kinase-activated protein kinase 2	Homo sapiens		 3.0							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434488&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625683	175446805		CHEMBL2385549				ZINC96270543	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064504	O=C1N(Cc2ccccc2-c2cncnc2)c2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C34H28N6O2/c35-18-23-5-7-24(8-6-23)32-17-27-15-26-16-29(39-13-11-36-12-14-39)9-10-31(26)40(34(41)33(27)42-32)21-25-3-1-2-4-30(25)28-19-37-22-38-20-28/h1-10,16-17,19-20,22,36H,11-15,21H2	LEXOCJKTBRIGNK-UHFFFAOYSA-N	50434486	CHEMBL2385548	MAP kinase-activated protein kinase 2	Homo sapiens		 1.9							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434486&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53235497	175446803		CHEMBL2385548				ZINC72314980	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064505	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3cncnc3)C(=O)c2o1)N1CCNCC1	InChI=1S/C33H28ClN5O2/c34-27-7-5-22(6-8-27)31-17-25-15-24-16-28(38-13-11-35-12-14-38)9-10-30(24)39(33(40)32(25)41-31)20-23-3-1-2-4-29(23)26-18-36-21-37-19-26/h1-10,16-19,21,35H,11-15,20H2	DUPVSFMZABNMJA-UHFFFAOYSA-N	50434489	CHEMBL2385547	MAP kinase-activated protein kinase 2	Homo sapiens		 5.7							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434489&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251322	175446806		CHEMBL2385547				ZINC72314982	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064506	COc1ccncc1-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C36H31N5O3/c1-43-33-12-13-39-22-31(33)30-5-3-2-4-26(30)23-41-32-11-10-29(40-16-14-38-15-17-40)19-27(32)18-28-20-34(44-35(28)36(41)42)25-8-6-24(21-37)7-9-25/h2-13,19-20,22,38H,14-18,23H2,1H3	CSBGNVBFRVOCQG-UHFFFAOYSA-N	50434490	CHEMBL2385546	MAP kinase-activated protein kinase 2	Homo sapiens		 6.8							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434490&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625569	175446807		CHEMBL2385546				ZINC96270544	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064507	COc1ncccc1-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C36H31N5O3/c1-43-35-31(7-4-14-39-35)30-6-3-2-5-26(30)23-41-32-13-12-29(40-17-15-38-16-18-40)20-27(32)19-28-21-33(44-34(28)36(41)42)25-10-8-24(22-37)9-11-25/h2-14,20-21,38H,15-19,23H2,1H3	NCJWOQTWADZUFB-UHFFFAOYSA-N	50434491	CHEMBL2385545	MAP kinase-activated protein kinase 2	Homo sapiens		 8.4							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434491&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625568	175446808		CHEMBL2385545				ZINC96270545	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064508	O=C1N(Cc2ccccc2-c2cccnc2)c2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C35H29N5O2/c36-21-24-7-9-25(10-8-24)33-20-29-18-28-19-30(39-16-14-37-15-17-39)11-12-32(28)40(35(41)34(29)42-33)23-27-4-1-2-6-31(27)26-5-3-13-38-22-26/h1-13,19-20,22,37H,14-18,23H2	KYNBQJNSKSZBTG-UHFFFAOYSA-N	50434492	CHEMBL2385544	MAP kinase-activated protein kinase 2	Homo sapiens		 21							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434492&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625567	175446809		CHEMBL2385544				ZINC96270546	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064509	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3cccnc3)C(=O)c2o1)N1CCNCC1	InChI=1S/C34H29ClN4O2/c35-28-9-7-23(8-10-28)32-20-27-18-26-19-29(38-16-14-36-15-17-38)11-12-31(26)39(34(40)33(27)41-32)22-25-4-1-2-6-30(25)24-5-3-13-37-21-24/h1-13,19-21,36H,14-18,22H2	WCQPZKBEGJASRO-UHFFFAOYSA-N	50434485	CHEMBL2385543	MAP kinase-activated protein kinase 2	Homo sapiens		 22							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434485&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251320	175446802		CHEMBL2385543				ZINC72314983	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064510	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3-c3ccncc3)C(=O)c2o1)N1CCNCC1	InChI=1S/C34H29ClN4O2/c35-28-7-5-24(6-8-28)32-21-27-19-26-20-29(38-17-15-37-16-18-38)9-10-31(26)39(34(40)33(27)41-32)22-25-3-1-2-4-30(25)23-11-13-36-14-12-23/h1-14,20-21,37H,15-19,22H2	MPRLYSREXMUHKP-UHFFFAOYSA-N	50434493	CHEMBL2385085	MAP kinase-activated protein kinase 2	Homo sapiens		 39							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434493&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251481	175446810		CHEMBL2385085				ZINC96270547	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064511	COc1cncc(c1)-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C36H31N5O3/c1-43-31-18-29(21-39-22-31)32-5-3-2-4-26(32)23-41-33-11-10-30(40-14-12-38-13-15-40)17-27(33)16-28-19-34(44-35(28)36(41)42)25-8-6-24(20-37)7-9-25/h2-11,17-19,21-22,38H,12-16,23H2,1H3	JSGDYRNNHHJYEH-UHFFFAOYSA-N	50434494	CHEMBL2385542	MAP kinase-activated protein kinase 2	Homo sapiens		 4.9							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625566	175446811		CHEMBL2385542				ZINC96270548	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064512	COc1cc(ccn1)-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(Cl)cc1)N1CCNCC1	InChI=1S/C35H31ClN4O3/c1-42-33-21-24(12-13-38-33)30-5-3-2-4-25(30)22-40-31-11-10-29(39-16-14-37-15-17-39)19-26(31)18-27-20-32(43-34(27)35(40)41)23-6-8-28(36)9-7-23/h2-13,19-21,37H,14-18,22H2,1H3	WGMIYGDWZXOMOW-UHFFFAOYSA-N	50434495	CHEMBL2385541	MAP kinase-activated protein kinase 2	Homo sapiens		 21							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434495	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434495&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251787	175446812		CHEMBL2385541				ZINC96270549	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064513	Fc1cncc(c1)-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C35H28FN5O2/c36-29-16-28(20-39-21-29)31-4-2-1-3-25(31)22-41-32-10-9-30(40-13-11-38-12-14-40)17-26(32)15-27-18-33(43-34(27)35(41)42)24-7-5-23(19-37)6-8-24/h1-10,16-18,20-21,38H,11-15,22H2	VLXNAWWKDVUEPE-UHFFFAOYSA-N	50434496	CHEMBL2385540	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434496&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625455	175446813		CHEMBL2385540				ZINC96270550	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064514	Fc1cccc(c1)-c1ccccc1CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C36H29FN4O2/c37-30-6-3-5-26(19-30)32-7-2-1-4-27(32)23-41-33-13-12-31(40-16-14-39-15-17-40)20-28(33)18-29-21-34(43-35(29)36(41)42)25-10-8-24(22-38)9-11-25/h1-13,19-21,39H,14-18,23H2	CJKPHLQODPUGAH-UHFFFAOYSA-N	50434497	CHEMBL2385539	MAP kinase-activated protein kinase 2	Homo sapiens		 74							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434497&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625454	175446814		CHEMBL2385539				ZINC96270551	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064515	O=C1Nc2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)C1CCNCC1	InChI=1S/C24H21N3O2/c25-14-15-1-3-17(4-2-15)22-13-20-12-19-11-18(16-7-9-26-10-8-16)5-6-21(19)27-24(28)23(20)29-22/h1-6,11,13,16,26H,7-10,12H2,(H,27,28)	KZYAIFYHLSZDDZ-UHFFFAOYSA-N	50434498	CHEMBL2385538	MAP kinase-activated protein kinase 2	Homo sapiens		 28							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434498&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625570	175446815		CHEMBL2385538				ZINC96270552	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064516	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3NC(=O)c2o1)C1CCNCC1	InChI=1S/C23H21ClN2O2/c24-19-4-1-15(2-5-19)21-13-18-12-17-11-16(14-7-9-25-10-8-14)3-6-20(17)26-23(27)22(18)28-21/h1-6,11,13-14,25H,7-10,12H2,(H,26,27)	RDLGFGGONWCSDW-UHFFFAOYSA-N	50434499	CHEMBL2385537	MAP kinase-activated protein kinase 2	Homo sapiens		 14							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434499&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251940	175446816		CHEMBL2385537				ZINC96270553	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064517	O=C1Nc2ccc(cc2Cc2cc(oc12)-c1ccc(cc1)C#N)N1CCNCC1	InChI=1S/C23H20N4O2/c24-14-15-1-3-16(4-2-15)21-13-18-11-17-12-19(27-9-7-25-8-10-27)5-6-20(17)26-23(28)22(18)29-21/h1-6,12-13,25H,7-11H2,(H,26,28)	YWYHWXBABMENQU-UHFFFAOYSA-N	50362171	CHEMBL1938683	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362171	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362171&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251321	136966233		CHEMBL1938683				ZINC82158226	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064518	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccc3Br)C(=O)c2o1)N1CCNCC1	InChI=1S/C29H25BrClN3O2/c30-25-4-2-1-3-20(25)18-34-26-10-9-24(33-13-11-32-12-14-33)16-21(26)15-22-17-27(36-28(22)29(34)35)19-5-7-23(31)8-6-19/h1-10,16-17,32H,11-15,18H2	NSLGZLPTXLKHAV-UHFFFAOYSA-N	50434500	CHEMBL2385536	MAP kinase-activated protein kinase 2	Homo sapiens		 52							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434500&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251319	175446817		CHEMBL2385536				ZINC96270554	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064519	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(Cc3ccccn3)C(=O)c2o1)N1CCNCC1	InChI=1S/C28H25ClN4O2/c29-22-6-4-19(5-7-22)26-17-21-15-20-16-24(32-13-11-30-12-14-32)8-9-25(20)33(28(34)27(21)35-26)18-23-3-1-2-10-31-23/h1-10,16-17,30H,11-15,18H2	BPZRWYHATAWWSF-UHFFFAOYSA-N	50434501	CHEMBL2385535	MAP kinase-activated protein kinase 2	Homo sapiens		 64							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434501&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251162	175446818		CHEMBL2385535				ZINC96270555	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064520	FC(F)CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(Cl)cc1)N1CCNCC1	InChI=1S/C24H22ClF2N3O2/c25-18-3-1-15(2-4-18)21-13-17-11-16-12-19(29-9-7-28-8-10-29)5-6-20(16)30(14-22(26)27)24(31)23(17)32-21/h1-6,12-13,22,28H,7-11,14H2	QXQMRAROSYXRCW-UHFFFAOYSA-N	50434502	CHEMBL2385534	MAP kinase-activated protein kinase 2	Homo sapiens		 107							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434502&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251479	175446819		CHEMBL2385534				ZINC96270556	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064521	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(CC3CC3)C(=O)c2o1)N1CCNCC1	InChI=1S/C26H26ClN3O2/c27-21-5-3-18(4-6-21)24-15-20-13-19-14-22(29-11-9-28-10-12-29)7-8-23(19)30(16-17-1-2-17)26(31)25(20)32-24/h3-8,14-15,17,28H,1-2,9-13,16H2	RNMFRPXZTMBUSM-UHFFFAOYSA-N	50434503	CHEMBL2385533	MAP kinase-activated protein kinase 2	Homo sapiens		 110							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434503	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434503&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251480	175446820		CHEMBL2385533				ZINC96270557	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064522	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3N(CC=C)C(=O)c2o1)N1CCNCC1	InChI=1S/C25H24ClN3O2/c1-2-11-29-22-8-7-21(28-12-9-27-10-13-28)15-18(22)14-19-16-23(31-24(19)25(29)30)17-3-5-20(26)6-4-17/h2-8,15-16,27H,1,9-14H2	XBBIPFACLROYIA-UHFFFAOYSA-N	50434504	CHEMBL2385532	MAP kinase-activated protein kinase 2	Homo sapiens		 12							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434504&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			71625453	175446821		CHEMBL2385532				ZINC96270558	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064523	CN1c2ccc(cc2Cc2cc(oc2C1=O)-c1ccc(Cl)cc1)N1CCNCC1	InChI=1S/C23H22ClN3O2/c1-26-20-7-6-19(27-10-8-25-9-11-27)13-16(20)12-17-14-21(29-22(17)23(26)28)15-2-4-18(24)5-3-15/h2-7,13-14,25H,8-12H2,1H3	SIJOROVRMMKDAO-UHFFFAOYSA-N	50434505	CHEMBL2385531	MAP kinase-activated protein kinase 2	Homo sapiens		 79							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50434505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50434505&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251323	175446822		CHEMBL2385531				ZINC96270559	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51064524	Clc1ccc(cc1)-c1cc2Cc3cc(ccc3NC(=O)c2o1)N1CCNCC1	InChI=1S/C22H20ClN3O2/c23-17-3-1-14(2-4-17)20-13-16-11-15-12-18(26-9-7-24-8-10-26)5-6-19(15)25-22(27)21(16)28-20/h1-6,12-13,24H,7-11H2,(H,25,27)	FUZHDIGYHQYSHU-UHFFFAOYSA-N	50362170	CHEMBL1938682	MAP kinase-activated protein kinase 2	Homo sapiens		 96							ChEMBL	10.1016/j.bmcl.2013.03.109	10.7270/Q2ZS2XX8	23602398			Xiao, D; Palani, A; Huang, X; Sofolarides, M; Zhou, W; Chen, X; Aslanian, R; Guo, Z; Fossetta, J; Tian, F; Trivedi, P; Spacciapoli, P; Whitehurst, CE; Lundell, D	Merck Research Laboratories	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50362170	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50362170&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			53251635	136966232		CHEMBL1938682				ZINC82158225	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50546879	CC1(C)C(=O)N([C@H]2CCc3c2cccc3O)c2nc(Nc3ccccc3)ncc12	InChI=1S/C23H22N4O2/c1-23(2)17-13-24-22(25-14-7-4-3-5-8-14)26-20(17)27(21(23)29)18-12-11-16-15(18)9-6-10-19(16)28/h3-10,13,18,28H,11-12H2,1-2H3,(H,24,25,26)/t18-/m0/s1	XLFNLJYGUOLEJS-SFHVURJKSA-N	50208911	CHEMBL3884319	MAP kinase-activated protein kinase 2	Homo sapiens		 10000							ChEMBL	10.1016/j.bmcl.2016.08.068	10.7270/Q2N018JC	27816515			Katz, JD; Haidle, A; Childers, KK; Zabierek, AA; Jewell, JP; Hou, Y; Altman, MD; Szewczak, A; Chen, D; Harsch, A; Hayashi, M; Warren, L; Hutton, M; Nuthall, H; Su, HP; Munshi, S; Stanton, MG; Davies, IW; Munoz, B; Northrup, A	Merck & Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50208911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50208911&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			69036886	375982220		CHEMBL3884319					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50552522	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)nc2)C(=O)N1	InChI=1S/C21H18N4OS/c1-11-3-4-13(10-22-11)15-6-5-14-16(25-15)7-8-17-18(14)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1	CMWRPDHVGMHLSZ-GFCCVEGCSA-N	50395272	CHEMBL1231206	MAP kinase-activated protein kinase 2	Homo sapiens	 5.0								ChEMBL	10.1038/nrd.2016.266	10.7270/Q2125VNC	28280261			Munoz, L	The University of Sydney	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395272&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B97	3FYJ,6T8X,7NRY	44631903	163344296		CHEMBL1231206	DB07430			ZINC39258365	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
50718984	CN(C)CCn1cc(cn1)-c1ccn2c(cnc2c1)-c1ccc(C(N)=O)c(OCc2cccc(F)c2)c1	InChI=1S/C28H27FN6O2/c1-33(2)10-11-34-17-22(15-32-34)20-8-9-35-25(16-31-27(35)14-20)21-6-7-24(28(30)36)26(13-21)37-18-19-4-3-5-23(29)12-19/h3-9,12-17H,10-11,18H2,1-2H3,(H2,30,36)	CGECJCJUHCZZGO-UHFFFAOYSA-N	50234990	CHEMBL4062453	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.ejmech.2016.12.026	10.7270/Q2GT5QFN	28039836			Xi, JB; Fang, YF; Frett, B; Zhu, ML; Zhu, T; Kong, YN; Guan, FJ; Zhao, Y; Zhang, XW; Li, HY; Ma, ML; Hu, W	East China Normal University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50234990	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50234990&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			137636872	384990906		CHEMBL4062453					1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689467	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ccc5[N+]([O-])=O)ccc4c23)C(=O)N1	InChI=1S/C21H16FN5O3S/c1-10-9-23-19-18-12-3-7-17(26-14-8-11(22)2-5-15(14)27(29)30)25-13(12)4-6-16(18)31-20(19)21(28)24-10/h2-8,10,23H,9H2,1H3,(H,24,28)(H,25,26)/t10-/m1/s1	ZPDPRJYSCGBCGN-SNVBAGLBSA-N	348745	US9790235, Number I-1	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348745	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348745&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611199	386050509							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689468	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ccc5C#N)ccc4c23)C(=O)N1	InChI=1S/C22H16FN5OS/c1-11-10-25-20-19-14-4-7-18(28-16-8-13(23)3-2-12(16)9-24)27-15(14)5-6-17(19)30-21(20)22(29)26-11/h2-8,11,25H,10H2,1H3,(H,26,29)(H,27,28)/t11-/m1/s1	KOXKODZIDWWDNO-LLVKDONJSA-N	348746	US9790235, Number I-2	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348746	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348746&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937040	386050510							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689469	C[C@@H]1CNc2c(sc3ccc4nc(Nc5ccnc(F)c5)ccc4c23)C(=O)N1	InChI=1S/C20H16FN5OS/c1-10-9-23-18-17-12-2-5-16(25-11-6-7-22-15(21)8-11)26-13(12)3-4-14(17)28-19(18)20(27)24-10/h2-8,10,23H,9H2,1H3,(H,24,27)(H,22,25,26)/t10-/m1/s1	YRLDBRWCJYDVKP-SNVBAGLBSA-N	348747	US9790235, Number I-3	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348747	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348747&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936817	386050511							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689470	C[C@@H]1CNc2c(sc3ccc4nc(Nc5ccnc(Cl)c5)ccc4c23)C(=O)N1	InChI=1S/C20H16ClN5OS/c1-10-9-23-18-17-12-2-5-16(25-11-6-7-22-15(21)8-11)26-13(12)3-4-14(17)28-19(18)20(27)24-10/h2-8,10,23H,9H2,1H3,(H,24,27)(H,22,25,26)/t10-/m1/s1	UTJXMKIBSWTBIS-SNVBAGLBSA-N	348748	US9790235, Number I-4	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348748	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348748&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936995	386050512							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689471	C[C@@H]1CNc2c(sc3ccc4nc(Nc5ccnc(Cl)n5)ccc4c23)C(=O)N1	InChI=1S/C19H15ClN6OS/c1-9-8-22-16-15-10-2-5-13(25-14-6-7-21-19(20)26-14)24-11(10)3-4-12(15)28-17(16)18(27)23-9/h2-7,9,22H,8H2,1H3,(H,23,27)(H,21,24,25,26)/t9-/m1/s1	QJZDJDAKEDVGHV-SECBINFHSA-N	348750	US9790235, Number I-5	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348750	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348750&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936867	386050514							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689472	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(F)c5)ccc4c23)C(=O)N1	InChI=1S/C20H15F2N5OS/c1-9-8-23-18-17-11-2-5-16(25-10-6-14(21)27-15(22)7-10)26-12(11)3-4-13(17)29-19(18)20(28)24-9/h2-7,9,23H,8H2,1H3,(H,24,28)(H,25,26,27)/t9-/m1/s1	DXTNKQUELUESFQ-SECBINFHSA-N	348751	US9790235, Number I-6	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348751	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348751&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936806	386050515							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689473	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H15ClN6OS/c1-9-7-21-17-16-10-2-5-14(26-15-6-13(20)22-8-23-15)25-11(10)3-4-12(16)28-18(17)19(27)24-9/h2-6,8-9,21H,7H2,1H3,(H,24,27)(H,22,23,25,26)/t9-/m1/s1	NOFJNUKFUPIGMZ-SECBINFHSA-N	348753	US9790235, Number I-7	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348753	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348753&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936929	386050517							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689474	C[C@@H]1CNc2c(sc3ccc4nc(Nc5ccnc(F)n5)ccc4c23)C(=O)N1	InChI=1S/C19H15FN6OS/c1-9-8-22-16-15-10-2-5-13(25-14-6-7-21-19(20)26-14)24-11(10)3-4-12(15)28-17(16)18(27)23-9/h2-7,9,22H,8H2,1H3,(H,23,27)(H,21,24,25,26)/t9-/m1/s1	AFIJFXDPPVNQAO-SECBINFHSA-N	348754	US9790235, Number I-8	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348754	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348754&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936873	386050518							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689475	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)ncc5C(N)=O)ccc4c23)C(=O)N1	InChI=1S/C20H16ClN7O2S/c1-8-6-23-15-14-9-2-5-13(27-18-10(17(22)29)7-24-20(21)28-18)26-11(9)3-4-12(14)31-16(15)19(30)25-8/h2-5,7-8,23H,6H2,1H3,(H2,22,29)(H,25,30)(H,24,26,27,28)/t8-/m1/s1	GKXYZYSHBIGXPA-MRVPVSSYSA-N	348755	US9790235, Number I-9	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348755&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936861	386050519							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689476	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)nc(n5)N5CCN(C)CC5)ccc4c23)C(=O)N1	InChI=1S/C23H24ClN9OS/c1-12-11-25-18-17-13-3-6-16(27-14(13)4-5-15(17)35-19(18)20(34)26-12)28-22-29-21(24)30-23(31-22)33-9-7-32(2)8-10-33/h3-6,12,25H,7-11H2,1-2H3,(H,26,34)(H,27,28,29,30,31)/t12-/m1/s1	KUPQUWQVPVAVKH-GFCCVEGCSA-N	348757	US9790235, Number I-10	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348757	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348757&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937037	386050521							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689477	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H15FN6OS/c1-9-7-21-17-16-10-2-5-14(26-15-6-13(20)22-8-23-15)25-11(10)3-4-12(16)28-18(17)19(27)24-9/h2-6,8-9,21H,7H2,1H3,(H,24,27)(H,22,23,25,26)/t9-/m1/s1	RRCPUMPDKMAEEW-SECBINFHSA-N	348759	US9790235, Number I-11	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348759	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348759&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936831	386050523							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689478	CCOC(=O)c1cnc(SC)nc1Nc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H22N6O3S2/c1-4-32-22(31)13-10-25-23(33-3)29-20(13)28-16-8-5-12-14(27-16)6-7-15-17(12)18-19(34-15)21(30)26-11(2)9-24-18/h5-8,10-11,24H,4,9H2,1-3H3,(H,26,30)(H,25,27,28,29)/t11-/m1/s1	LRMUOYHVJZQNHD-LLVKDONJSA-N	348760	US9790235, Number I-12	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348760	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348760&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118943830	386050524							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689479	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nccc(Cl)n5)ccc4c23)C(=O)N1	InChI=1S/C19H15ClN6OS/c1-9-8-22-16-15-10-2-5-14(26-19-21-7-6-13(20)25-19)24-11(10)3-4-12(15)28-17(16)18(27)23-9/h2-7,9,22H,8H2,1H3,(H,23,27)(H,21,24,25,26)/t9-/m1/s1	QFWPZRYSEPLDPE-SECBINFHSA-N	348761	US9790235, Number I-13	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348761	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348761&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937039	386050525							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689480	C[C@@H]1CNc2c(sc3ccc4nc(Nc5ccnc(n5)S(C)(=O)=O)ccc4c23)C(=O)N1	InChI=1S/C20H18N6O3S2/c1-10-9-22-17-16-11-3-6-14(25-15-7-8-21-20(26-15)31(2,28)29)24-12(11)4-5-13(16)30-18(17)19(27)23-10/h3-8,10,22H,9H2,1-2H3,(H,23,27)(H,21,24,25,26)/t10-/m1/s1	HAXFSVNJEDNKJC-SNVBAGLBSA-N	348762	US9790235, Number I-14	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348762	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348762&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936863	386050526							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689481	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)ncc5C(N)=O)ccc4c23)C(=O)N1	InChI=1S/C21H17ClN6O2S/c1-9-7-25-18-17-10-2-5-16(28-13-6-15(22)24-8-11(13)20(23)29)27-12(10)3-4-14(17)31-19(18)21(30)26-9/h2-6,8-9,25H,7H2,1H3,(H2,23,29)(H,26,30)(H,24,27,28)/t9-/m1/s1	FPQJQVGZWNTIMP-SECBINFHSA-N	348763	US9790235, Number I-15	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348763	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348763&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936968	386050527							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689482	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)ncc5C#N)ccc4c23)C(=O)N1	InChI=1S/C20H14ClN7OS/c1-9-7-23-16-15-11-2-5-14(27-18-10(6-22)8-24-20(21)28-18)26-12(11)3-4-13(15)30-17(16)19(29)25-9/h2-5,8-9,23H,7H2,1H3,(H,25,29)(H,24,26,27,28)/t9-/m1/s1	RQJBZCQSECCEQT-SECBINFHSA-N	348765	US9790235, Number I-16	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348765	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348765&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936966	386050529							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689483	OC[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H15FN6O2S/c20-13-5-15(23-8-22-13)26-14-4-1-10-11(25-14)2-3-12-16(10)17-18(29-12)19(28)24-9(7-27)6-21-17/h1-5,8-9,21,27H,6-7H2,(H,24,28)(H,22,23,25,26)/t9-/m0/s1	HJZTVWSOIJWTEU-VIFPVBQESA-N	348766	US9790235, Number I-17	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348766	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348766&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936887	386050530							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689484	CCOC(=O)c1cnc(Cl)nc1Nc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H19ClN6O3S/c1-3-32-21(31)12-9-25-22(23)29-19(12)28-15-7-4-11-13(27-15)5-6-14-16(11)17-18(33-14)20(30)26-10(2)8-24-17/h4-7,9-10,24H,3,8H2,1-2H3,(H,26,30)(H,25,27,28,29)/t10-/m1/s1	TWFKBVMMQBATBD-SNVBAGLBSA-N	348767	US9790235, Number I-18	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348767	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348767&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118943831	386050531							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689485	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)ncc5C(=O)NC5CCN(C)CC5)ccc4c23)C(=O)N1	InChI=1S/C26H27ClN8O2S/c1-13-11-28-21-20-15-3-6-19(32-17(15)4-5-18(20)38-22(21)25(37)30-13)33-23-16(12-29-26(27)34-23)24(36)31-14-7-9-35(2)10-8-14/h3-6,12-14,28H,7-11H2,1-2H3,(H,30,37)(H,31,36)(H,29,32,33,34)/t13-/m1/s1	OEWVKNVIKPKKEM-CYBMUJFWSA-N	348768	US9790235, Number I-19	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348768	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348768&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936868	386050532							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689486	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)ncc5C(=O)NC5COC5)ccc4c23)C(=O)N1	InChI=1S/C23H20ClN7O3S/c1-10-6-25-18-17-12-2-5-16(29-14(12)3-4-15(17)35-19(18)22(33)27-10)30-20-13(7-26-23(24)31-20)21(32)28-11-8-34-9-11/h2-5,7,10-11,25H,6,8-9H2,1H3,(H,27,33)(H,28,32)(H,26,29,30,31)/t10-/m1/s1	NNPXLTYKOPAIHB-SNVBAGLBSA-N	348769	US9790235, Number I-20	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348769	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348769&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936952	386050533							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689487	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)ncc5C(=O)NC5CC5)ccc4c23)C(=O)N1	InChI=1S/C23H20ClN7O2S/c1-10-8-25-18-17-12-4-7-16(29-14(12)5-6-15(17)34-19(18)22(33)27-10)30-20-13(9-26-23(24)31-20)21(32)28-11-2-3-11/h4-7,9-11,25H,2-3,8H2,1H3,(H,27,33)(H,28,32)(H,26,29,30,31)/t10-/m1/s1	UDPPHAJMUIGUFW-SNVBAGLBSA-N	348770	US9790235, Number I-21	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348770	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348770&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936814	386050534							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689488	OC[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H15ClN6O2S/c20-13-5-15(23-8-22-13)26-14-4-1-10-11(25-14)2-3-12-16(10)17-18(29-12)19(28)24-9(7-27)6-21-17/h1-5,8-9,21,27H,6-7H2,(H,24,28)(H,22,23,25,26)/t9-/m0/s1	DTQNXEBTPZTFFY-VIFPVBQESA-N	348771	US9790235, Number I-22	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348771	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348771&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936862	386050535							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689489	CCOC(=O)c1cnc(Nc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)nc1Cl	InChI=1S/C22H19ClN6O3S/c1-3-32-21(31)12-9-25-22(29-19(12)23)28-15-7-4-11-13(27-15)5-6-14-16(11)17-18(33-14)20(30)26-10(2)8-24-17/h4-7,9-10,24H,3,8H2,1-2H3,(H,26,30)(H,25,27,28,29)/t10-/m1/s1	CKHVYGBUYNVHIM-SNVBAGLBSA-N	348772	US9790235, Number I-23	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348772	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348772&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118943832	386050536							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689490	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)ncc5C(=O)N5CC[C@H](C5)N(C)C)ccc4c23)C(=O)N1	InChI=1S/C26H27ClN8O2S/c1-13-10-28-21-20-15-4-7-19(31-17(15)5-6-18(20)38-22(21)24(36)30-13)32-23-16(11-29-26(27)33-23)25(37)35-9-8-14(12-35)34(2)3/h4-7,11,13-14,28H,8-10,12H2,1-3H3,(H,30,36)(H,29,31,32,33)/t13-,14-/m1/s1	OCJLUCCJOUHBMA-ZIAGYGMSSA-N	348773	US9790235, Number I-24	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348773	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348773&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936855	386050537							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689491	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)ncc5C#N)ccc4c23)C(=O)N1	InChI=1S/C21H15ClN6OS/c1-10-8-25-19-18-12-2-5-17(28-14-6-16(22)24-9-11(14)7-23)27-13(12)3-4-15(18)30-20(19)21(29)26-10/h2-6,9-10,25H,8H2,1H3,(H,26,29)(H,24,27,28)/t10-/m1/s1	PCRFKPGZNRPTSG-SNVBAGLBSA-N	348774	US9790235, Number I-25	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348774	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348774&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936990	386050538							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689492	NC[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H16FN7OS/c20-13-5-15(24-8-23-13)27-14-4-1-10-11(26-14)2-3-12-16(10)17-18(29-12)19(28)25-9(6-21)7-22-17/h1-5,8-9,22H,6-7,21H2,(H,25,28)(H,23,24,26,27)/t9-/m1/s1	IRGPJMRBSSGXDZ-SECBINFHSA-N	348775	US9790235, Number I-26	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348775	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348775&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936937	386050539							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689493	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncc5C#N)ccc4c23)C(=O)N1	InChI=1S/C21H15FN6OS/c1-10-8-25-19-18-12-2-5-17(28-14-6-16(22)24-9-11(14)7-23)27-13(12)3-4-15(18)30-20(19)21(29)26-10/h2-6,9-10,25H,8H2,1H3,(H,26,29)(H,24,27,28)/t10-/m1/s1	UNTVTOZEEWWTFA-SNVBAGLBSA-N	348776	US9790235, Number I-27	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348776	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348776&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936838	386050540							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689494	NC[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H16ClN7OS/c20-13-5-15(24-8-23-13)27-14-4-1-10-11(26-14)2-3-12-16(10)17-18(29-12)19(28)25-9(6-21)7-22-17/h1-5,8-9,22H,6-7,21H2,(H,25,28)(H,23,24,26,27)/t9-/m1/s1	GTNDXUXKZFKVRN-SECBINFHSA-N	348777	US9790235, Number I-28	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348777	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348777&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936999	386050541							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689495	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncc5C(N)=O)ccc4c23)C(=O)N1	InChI=1S/C21H17FN6O2S/c1-9-7-25-18-17-10-2-5-16(28-13-6-15(22)24-8-11(13)20(23)29)27-12(10)3-4-14(17)31-19(18)21(30)26-9/h2-6,8-9,25H,7H2,1H3,(H2,23,29)(H,26,30)(H,24,27,28)/t9-/m1/s1	IDJBLLBDCJYQCB-SECBINFHSA-N	348778	US9790235, Number I-29	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348778&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937035	386050542							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689496	NC(=O)c1cnc(Cl)nc1Nc1ccc2c3c4NC[C@@H](CO)NC(=O)c4sc3ccc2n1	InChI=1S/C20H16ClN7O3S/c21-20-24-6-10(17(22)30)18(28-20)27-13-4-1-9-11(26-13)2-3-12-14(9)15-16(32-12)19(31)25-8(7-29)5-23-15/h1-4,6,8,23,29H,5,7H2,(H2,22,30)(H,25,31)(H,24,26,27,28)/t8-/m0/s1	XDYKAYYRDDPWBL-QMMMGPOBSA-N	348779	US9790235, Number I-30	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348779&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936857	386050543							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689497	CN(C)C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncn5)ccc4c23)C(=O)N1	InChI=1S/C21H20FN7OS/c1-29(2)9-11-8-23-19-18-12-3-6-16(28-17-7-15(22)24-10-25-17)27-13(12)4-5-14(18)31-20(19)21(30)26-11/h3-7,10-11,23H,8-9H2,1-2H3,(H,26,30)(H,24,25,27,28)/t11-/m0/s1	ZNZAUCLAOHGMFG-NSHDSACASA-N	348780	US9790235, Number I-31	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348780&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936964	386050544							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689498	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(OCCN(C)C)n5)ccc4c23)C(=O)N1	InChI=1S/C23H24FN7O2S/c1-12-11-25-20-19-13-4-7-17(27-14(13)5-6-15(19)34-21(20)22(32)26-12)29-18-10-16(24)28-23(30-18)33-9-8-31(2)3/h4-7,10,12,25H,8-9,11H2,1-3H3,(H,26,32)(H,27,28,29,30)/t12-/m1/s1	LBLVYDSCHIARCI-GFCCVEGCSA-N	348781	US9790235, Number I-32	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348781	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348781&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937046	386050545							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689499	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)N(CCN(C)C)c2cc(F)ncn2)C(=O)N1	InChI=1S/C23H24FN7OS/c1-13-11-25-21-20-14-4-7-18(29-15(14)5-6-16(20)33-22(21)23(32)28-13)31(9-8-30(2)3)19-10-17(24)26-12-27-19/h4-7,10,12-13,25H,8-9,11H2,1-3H3,(H,28,32)/t13-/m1/s1	KAWXGOCFLLRCOO-CYBMUJFWSA-N	348782	US9790235, Number I-33	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348782	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348782&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937000	386050546							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689500	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)N(C)c2nc(Cl)ncc2C(N)=O)C(=O)N1	InChI=1S/C21H18ClN7O2S/c1-9-7-24-16-15-10-3-6-14(29(2)19-11(18(23)30)8-25-21(22)28-19)27-12(10)4-5-13(15)32-17(16)20(31)26-9/h3-6,8-9,24H,7H2,1-2H3,(H2,23,30)(H,26,31)/t9-/m1/s1	PIQULSLLKOYFBE-SECBINFHSA-N	348783	US9790235, Number I-34	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348783	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348783&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936977	386050547							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689501	CNC[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)ncn5)ccc4c23)C(=O)N1	InChI=1S/C20H18FN7OS/c1-22-7-10-8-23-18-17-11-2-5-15(28-16-6-14(21)24-9-25-16)27-12(11)3-4-13(17)30-19(18)20(29)26-10/h2-6,9-10,22-23H,7-8H2,1H3,(H,26,29)(H,24,25,27,28)/t10-/m1/s1	OSCGIKXSEZMPLR-SNVBAGLBSA-N	348784	US9790235, Number I-35	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348784&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937008	386050548							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689502	COCCN(c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)c1cc(F)ncn1	InChI=1S/C22H21FN6O2S/c1-12-10-24-20-19-13-3-6-17(29(7-8-31-2)18-9-16(23)25-11-26-18)28-14(13)4-5-15(19)32-21(20)22(30)27-12/h3-6,9,11-12,24H,7-8,10H2,1-2H3,(H,27,30)/t12-/m1/s1	JSRPHVISXUBQJD-GFCCVEGCSA-N	348785	US9790235, Number I-36	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348785&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936830	386050549							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689503	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(OC6COC6)n5)ccc4c23)C(=O)N1	InChI=1S/C22H19FN6O3S/c1-10-7-24-19-18-12-2-5-16(26-13(12)3-4-14(18)33-20(19)21(30)25-10)28-17-6-15(23)27-22(29-17)32-11-8-31-9-11/h2-6,10-11,24H,7-9H2,1H3,(H,25,30)(H,26,27,28,29)/t10-/m1/s1	DHKPTQDGFDWNEM-SNVBAGLBSA-N	348786	US9790235, Number I-37	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348786&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936899	386050550							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689504	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)N(C)c2cc(F)ncn2)C(=O)N1	InChI=1S/C20H17FN6OS/c1-10-8-22-18-17-11-3-6-15(27(2)16-7-14(21)23-9-24-16)26-12(11)4-5-13(17)29-19(18)20(28)25-10/h3-7,9-10,22H,8H2,1-2H3,(H,25,28)/t10-/m1/s1	NLVJBERCYZLYJC-SNVBAGLBSA-N	348787	US9790235, Number I-38	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348787	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348787&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936876	386050551							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689505	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(OCC6(C)COC6)n5)ccc4c23)C(=O)N1	InChI=1S/C24H23FN6O3S/c1-12-8-26-20-19-13-3-6-17(28-14(13)4-5-15(19)35-21(20)22(32)27-12)30-18-7-16(25)29-23(31-18)34-11-24(2)9-33-10-24/h3-7,12,26H,8-11H2,1-2H3,(H,27,32)(H,28,29,30,31)/t12-/m1/s1	XCTOSLYYNGDVAI-GFCCVEGCSA-N	348788	US9790235, Number I-39	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348788	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348788&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936912	386050552							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689506	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(O[C@H]6CCOC6)n5)ccc4c23)C(=O)N1	InChI=1S/C23H21FN6O3S/c1-11-9-25-20-19-13-2-5-17(27-14(13)3-4-15(19)34-21(20)22(31)26-11)29-18-8-16(24)28-23(30-18)33-12-6-7-32-10-12/h2-5,8,11-12,25H,6-7,9-10H2,1H3,(H,26,31)(H,27,28,29,30)/t11-,12+/m1/s1	GIFAJHOCMLHJDR-NEPJUHHUSA-N	348789	US9790235, Number I-40	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348789&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936902	386050553							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689507	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(O[C@@H]6CCOC6)n5)ccc4c23)C(=O)N1	InChI=1S/C23H21FN6O3S/c1-11-9-25-20-19-13-2-5-17(27-14(13)3-4-15(19)34-21(20)22(31)26-11)29-18-8-16(24)28-23(30-18)33-12-6-7-32-10-12/h2-5,8,11-12,25H,6-7,9-10H2,1H3,(H,26,31)(H,27,28,29,30)/t11-,12-/m1/s1	GIFAJHOCMLHJDR-VXGBXAGGSA-N	348790	US9790235, Number I-41	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348790&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937025	386050554							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689508	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(F)cc(OC6COC6)n5)ccc4c23)C(=O)N1	InChI=1S/C22H19FN6O3S/c1-10-7-24-19-18-12-2-5-16(26-13(12)3-4-14(18)33-20(19)21(30)25-10)28-22-27-15(23)6-17(29-22)32-11-8-31-9-11/h2-6,10-11,24H,7-9H2,1H3,(H,25,30)(H,26,27,28,29)/t10-/m1/s1	HSQNGUSEUXGKMD-SNVBAGLBSA-N	348791	US9790235, Number I-42	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348791	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348791&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936818	386050555							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689509	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(F)cc(OCC6(C)COC6)n5)ccc4c23)C(=O)N1	InChI=1S/C24H23FN6O3S/c1-12-8-26-20-19-13-3-6-17(28-14(13)4-5-15(19)35-21(20)22(32)27-12)30-23-29-16(25)7-18(31-23)34-11-24(2)9-33-10-24/h3-7,12,26H,8-11H2,1-2H3,(H,27,32)(H,28,29,30,31)/t12-/m1/s1	UFMZBGMXUFGBJZ-GFCCVEGCSA-N	348792	US9790235, Number I-43	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348792	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348792&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936981	386050556							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689510	COCCOc1nc(F)cc(Nc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C22H21FN6O3S/c1-11-10-24-19-18-12-3-6-16(26-13(12)4-5-14(18)33-20(19)21(30)25-11)28-17-9-15(23)27-22(29-17)32-8-7-31-2/h3-6,9,11,24H,7-8,10H2,1-2H3,(H,25,30)(H,26,27,28,29)/t11-/m1/s1	DRTCSGBHGSSKPR-LLVKDONJSA-N	348793	US9790235, Number I-44	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348793	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348793&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118943834	386050557							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689511	COCCOc1cc(F)nc(Nc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C22H21FN6O3S/c1-11-10-24-19-18-12-3-6-16(26-13(12)4-5-14(18)33-20(19)21(30)25-11)28-22-27-15(23)9-17(29-22)32-8-7-31-2/h3-6,9,11,24H,7-8,10H2,1-2H3,(H,25,30)(H,26,27,28,29)/t11-/m1/s1	UMVJOGVSKNVQNT-LLVKDONJSA-N	348794	US9790235, Number I-45	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348794	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348794&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936809	386050558							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689512	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(F)cc(O[C@@H]6CCOC6)n5)ccc4c23)C(=O)N1	InChI=1S/C23H21FN6O3S/c1-11-9-25-20-19-13-2-5-17(27-14(13)3-4-15(19)34-21(20)22(31)26-11)29-23-28-16(24)8-18(30-23)33-12-6-7-32-10-12/h2-5,8,11-12,25H,6-7,9-10H2,1H3,(H,26,31)(H,27,28,29,30)/t11-,12-/m1/s1	QKTDVOFUQDXANO-VXGBXAGGSA-N	348795	US9790235, Number I-46	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348795&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936885	386050559							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689513	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(OC6CCCN(C)C6)n5)ccc4c23)C(=O)N1	InChI=1S/C25H26FN7O2S/c1-13-11-27-22-21-15-5-8-19(29-16(15)6-7-17(21)36-23(22)24(34)28-13)31-20-10-18(26)30-25(32-20)35-14-4-3-9-33(2)12-14/h5-8,10,13-14,27H,3-4,9,11-12H2,1-2H3,(H,28,34)(H,29,30,31,32)/t13-,14?/m1/s1	LCCRSNAYYXQSJN-KWCCSABGSA-N	348796	US9790235, Number I-47	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348796&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936993	386050560							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689514	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(OCCN6CCN(C)CC6)n5)ccc4c23)C(=O)N1	InChI=1S/C26H29FN8O2S/c1-15-14-28-23-22-16-3-6-20(30-17(16)4-5-18(22)38-24(23)25(36)29-15)32-21-13-19(27)31-26(33-21)37-12-11-35-9-7-34(2)8-10-35/h3-6,13,15,28H,7-12,14H2,1-2H3,(H,29,36)(H,30,31,32,33)/t15-/m1/s1	ZZLNUWRWEGKDQZ-OAHLLOKOSA-N	348797	US9790235, Number I-48	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348797&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936991	386050561							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689515	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(O[C@@H]6CCN(C)C6)n5)ccc4c23)C(=O)N1	InChI=1S/C24H24FN7O2S/c1-12-10-26-21-20-14-3-6-18(28-15(14)4-5-16(20)35-22(21)23(33)27-12)30-19-9-17(25)29-24(31-19)34-13-7-8-32(2)11-13/h3-6,9,12-13,26H,7-8,10-11H2,1-2H3,(H,27,33)(H,28,29,30,31)/t12-,13-/m1/s1	NFIJZTODXJCVRL-CHWSQXEVSA-N	348798	US9790235, Number I-49	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348798&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937030	386050562							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689516	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(F)cc(O[C@H]6CCOC6)n5)ccc4c23)C(=O)N1	InChI=1S/C23H21FN6O3S/c1-11-9-25-20-19-13-2-5-17(27-14(13)3-4-15(19)34-21(20)22(31)26-11)29-23-28-16(24)8-18(30-23)33-12-6-7-32-10-12/h2-5,8,11-12,25H,6-7,9-10H2,1H3,(H,26,31)(H,27,28,29,30)/t11-,12+/m1/s1	QKTDVOFUQDXANO-NEPJUHHUSA-N	348799	US9790235, Number I-50	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348799&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936939	386050563							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689517	COCc1nc(Cl)cc(Nc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C21H19ClN6O2S/c1-10-8-23-19-18-11-3-6-15(27-16-7-14(22)26-17(28-16)9-30-2)25-12(11)4-5-13(18)31-20(19)21(29)24-10/h3-7,10,23H,8-9H2,1-2H3,(H,24,29)(H,25,26,27,28)/t10-/m1/s1	WBXQREQYDSOOBW-SNVBAGLBSA-N	348800	US9790235, Number I-51	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348800&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936841	386050564							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689518	C[C@@H]1CNc2c(sc3ccc4nc(Oc5ccnc(F)n5)ccc4c23)C(=O)N1	InChI=1S/C19H14FN5O2S/c1-9-8-22-16-15-10-2-5-13(27-14-6-7-21-19(20)25-14)24-11(10)3-4-12(15)28-17(16)18(26)23-9/h2-7,9,22H,8H2,1H3,(H,23,26)/t9-/m1/s1	OCEQQHPRQVWYGN-SECBINFHSA-N	348801	US9790235, Number I-52	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348801&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936881	386050565							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689519	C[C@@H]1CNc2c(sc3ccc4nc(Oc5ccnc(Cl)n5)ccc4c23)C(=O)N1	InChI=1S/C19H14ClN5O2S/c1-9-8-22-16-15-10-2-5-13(27-14-6-7-21-19(20)25-14)24-11(10)3-4-12(15)28-17(16)18(26)23-9/h2-7,9,22H,8H2,1H3,(H,23,26)/t9-/m1/s1	BOKXDPGNOCYZTM-SECBINFHSA-N	348802	US9790235, Number I-53	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348802&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937041	386050566							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689520	C[C@@H]1CNc2c(sc3ccc4nc(Sc5cc(F)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H14FN5OS2/c1-9-7-21-17-16-10-2-5-14(28-15-6-13(20)22-8-23-15)25-11(10)3-4-12(16)27-18(17)19(26)24-9/h2-6,8-9,21H,7H2,1H3,(H,24,26)/t9-/m1/s1	ZFDIHXOMOVDUKM-SECBINFHSA-N	348803	US9790235, Number I-54	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348803&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936903	386050567							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689521	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cncc(Cl)n5)ccc4c23)C(=O)N1	InChI=1S/C19H14ClN5O2S/c1-9-6-22-17-16-10-2-5-14(27-15-8-21-7-13(20)25-15)24-11(10)3-4-12(16)28-18(17)19(26)23-9/h2-5,7-9,22H,6H2,1H3,(H,23,26)/t9-/m1/s1	SGXSWXXFRJOOBI-SECBINFHSA-N	348804	US9790235, Number I-55	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348804&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937019	386050568							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689522	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cc(Cl)ncn5)ccc4c23)C(=O)N1	InChI=1S/C19H14ClN5O2S/c1-9-7-21-17-16-10-2-5-14(27-15-6-13(20)22-8-23-15)25-11(10)3-4-12(16)28-18(17)19(26)24-9/h2-6,8-9,21H,7H2,1H3,(H,24,26)/t9-/m1/s1	OILUICPBJOXTGS-SECBINFHSA-N	348805	US9790235, Number I-56	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348805&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936980	386050569							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689523	COCc1nc(Cl)cc(Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C21H18ClN5O3S/c1-10-8-23-19-18-11-3-6-16(30-17-7-14(22)26-15(27-17)9-29-2)25-12(11)4-5-13(18)31-20(19)21(28)24-10/h3-7,10,23H,8-9H2,1-2H3,(H,24,28)/t10-/m1/s1	LDIVPNQIWIPVKY-SNVBAGLBSA-N	348806	US9790235, Number I-57	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348806&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936974	386050570							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689524	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cc(Cl)nc(C)n5)ccc4c23)C(=O)N1	InChI=1S/C20H16ClN5O2S/c1-9-8-22-18-17-11-3-6-15(28-16-7-14(21)24-10(2)25-16)26-12(11)4-5-13(17)29-19(18)20(27)23-9/h3-7,9,22H,8H2,1-2H3,(H,23,27)/t9-/m1/s1	MLOSZSZAOFIOHD-SECBINFHSA-N	348807	US9790235, Number I-58	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348807&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936872	386050571							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689525	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)nc(OC6CCCN(C)C6)n5)ccc4c23)C(=O)N1	InChI=1S/C25H26ClN7O2S/c1-13-11-27-22-21-15-5-8-19(29-16(15)6-7-17(21)36-23(22)24(34)28-13)31-20-10-18(26)30-25(32-20)35-14-4-3-9-33(2)12-14/h5-8,10,13-14,27H,3-4,9,11-12H2,1-2H3,(H,28,34)(H,29,30,31,32)/t13-,14?/m1/s1	BOFAWQFEHDOBEY-KWCCSABGSA-N	348808	US9790235, Number I-59	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348808&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936914	386050572							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689526	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)nc(O[C@@H]6CCN(C)C6)n5)ccc4c23)C(=O)N1	InChI=1S/C24H24ClN7O2S/c1-12-10-26-21-20-14-3-6-18(28-15(14)4-5-16(20)35-22(21)23(33)27-12)30-19-9-17(25)29-24(31-19)34-13-7-8-32(2)11-13/h3-6,9,12-13,26H,7-8,10-11H2,1-2H3,(H,27,33)(H,28,29,30,31)/t12-,13-/m1/s1	XPDGEIMRHLXWBJ-CHWSQXEVSA-N	348809	US9790235, Number I-60	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348809&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937043	386050573							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689527	C[C@@H]1CNc2c(sc3ccc4nc(Nc5nc(Cl)cc(OCCN6CCN(C)CC6)n5)ccc4c23)C(=O)N1	InChI=1S/C26H29ClN8O2S/c1-15-14-28-23-22-16-3-6-20(30-17(16)4-5-18(22)38-24(23)25(36)29-15)32-26-31-19(27)13-21(33-26)37-12-11-35-9-7-34(2)8-10-35/h3-6,13,15,28H,7-12,14H2,1-2H3,(H,29,36)(H,30,31,32,33)/t15-/m1/s1	CPPDSBJOGLXXGW-OAHLLOKOSA-N	348810	US9790235, Number I-61	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348810&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936804	386050574							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689528	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc(n5)N5CCCC5)ccc4c23)C(=O)N1	InChI=1S/C22H20ClN7O2S/c1-11-10-24-17-16-12-4-7-15(26-13(12)5-6-14(16)33-18(17)19(31)25-11)32-22-28-20(23)27-21(29-22)30-8-2-3-9-30/h4-7,11,24H,2-3,8-10H2,1H3,(H,25,31)/t11-/m1/s1	JQWJACJTSFCQKI-LLVKDONJSA-N	348811	US9790235, Number I-62	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348811&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936858	386050575							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689529	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc(n5)N5CCOCC5)ccc4c23)C(=O)N1	InChI=1S/C22H20ClN7O3S/c1-11-10-24-17-16-12-2-5-15(26-13(12)3-4-14(16)34-18(17)19(31)25-11)33-22-28-20(23)27-21(29-22)30-6-8-32-9-7-30/h2-5,11,24H,6-10H2,1H3,(H,25,31)/t11-/m1/s1	RQRVGVOXRWJDCU-LLVKDONJSA-N	348812	US9790235, Number I-63	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348812&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936839	386050576							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689530	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc(n5)N5CCCCC5)ccc4c23)C(=O)N1	InChI=1S/C23H22ClN7O2S/c1-12-11-25-18-17-13-5-8-16(27-14(13)6-7-15(17)34-19(18)20(32)26-12)33-23-29-21(24)28-22(30-23)31-9-3-2-4-10-31/h5-8,12,25H,2-4,9-11H2,1H3,(H,26,32)/t12-/m1/s1	VEKJSTKVIZVFPR-GFCCVEGCSA-N	348813	US9790235, Number I-64	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348813&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936847	386050577							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689531	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cc(F)nc(C)n5)ccc4c23)C(=O)N1	InChI=1S/C20H16FN5O2S/c1-9-8-22-18-17-11-3-6-15(28-16-7-14(21)24-10(2)25-16)26-12(11)4-5-13(17)29-19(18)20(27)23-9/h3-7,9,22H,8H2,1-2H3,(H,23,27)/t9-/m1/s1	IYGQWQJHAUZZMK-SECBINFHSA-N	348814	US9790235, Number I-65	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348814&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937012	386050578							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689532	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(Cl)nc(OCCN6CCN(C)CC6)n5)ccc4c23)C(=O)N1	InChI=1S/C26H29ClN8O2S/c1-15-14-28-23-22-16-3-6-20(30-17(16)4-5-18(22)38-24(23)25(36)29-15)32-21-13-19(27)31-26(33-21)37-12-11-35-9-7-34(2)8-10-35/h3-6,13,15,28H,7-12,14H2,1-2H3,(H,29,36)(H,30,31,32,33)/t15-/m1/s1	COJMXRSCTOIDJP-OAHLLOKOSA-N	348815	US9790235, Number I-66	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348815&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936827	386050579							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689533	COCCOc1nc(Cl)cc(Nc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C22H21ClN6O3S/c1-11-10-24-19-18-12-3-6-16(26-13(12)4-5-14(18)33-20(19)21(30)25-11)28-17-9-15(23)27-22(29-17)32-8-7-31-2/h3-6,9,11,24H,7-8,10H2,1-2H3,(H,25,30)(H,26,27,28,29)/t11-/m1/s1	QWGXSSACJAXYHU-LLVKDONJSA-N	348816	US9790235, Number I-67	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348816&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936928	386050580							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689534	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cc(Cl)nc(CO)n5)ccc4c23)C(=O)N1	InChI=1S/C20H16ClN5O3S/c1-9-7-22-18-17-10-2-5-15(29-16-6-13(21)25-14(8-27)26-16)24-11(10)3-4-12(17)30-19(18)20(28)23-9/h2-6,9,22,27H,7-8H2,1H3,(H,23,28)/t9-/m1/s1	IZHKDGWJPPJCRN-SECBINFHSA-N	348817	US9790235, Number I-68	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348817&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936915	386050581							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689535	COCCOc1cc(Cl)nc(Nc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C22H21ClN6O3S/c1-11-10-24-19-18-12-3-6-16(26-13(12)4-5-14(18)33-20(19)21(30)25-11)28-22-27-15(23)9-17(29-22)32-8-7-31-2/h3-6,9,11,24H,7-8,10H2,1-2H3,(H,25,30)(H,26,27,28,29)/t11-/m1/s1	APTIJGYCIBCMCO-LLVKDONJSA-N	348818	US9790235, Number I-69	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348818&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936832	386050582							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689536	COC(=O)c1nc(Cl)cc(Nc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C21H17ClN6O3S/c1-9-8-23-17-16-10-3-6-14(27-15-7-13(22)26-19(28-15)21(30)31-2)25-11(10)4-5-12(16)32-18(17)20(29)24-9/h3-7,9,23H,8H2,1-2H3,(H,24,29)(H,25,26,27,28)/t9-/m1/s1	XYXDZHXFMJFTTC-SECBINFHSA-N	348819	US9790235, Number I-70	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348819&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936936	386050583							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689537	COC(=O)c1nc(Cl)cc(Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C21H16ClN5O4S/c1-9-8-23-17-16-10-3-6-14(31-15-7-13(22)26-19(27-15)21(29)30-2)25-11(10)4-5-12(16)32-18(17)20(28)24-9/h3-7,9,23H,8H2,1-2H3,(H,24,28)/t9-/m1/s1	WLVQRBFAKWLNHP-SECBINFHSA-N	348820	US9790235, Number I-71	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348820&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937021	386050584							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689538	C[C@@H]1CNc2c(sc3ccc4nc(Sc5ccnc(Cl)n5)ccc4c23)C(=O)N1	InChI=1S/C19H14ClN5OS2/c1-9-8-22-16-15-10-2-5-13(28-14-6-7-21-19(20)25-14)24-11(10)3-4-12(15)27-17(16)18(26)23-9/h2-7,9,22H,8H2,1H3,(H,23,26)/t9-/m1/s1	PIIXTPQYNGPGDH-SECBINFHSA-N	348821	US9790235, Number I-72	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348821&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936926	386050585							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689539	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(CN6CCN(C)CC6)n5)ccc4c23)C(=O)N1	InChI=1S/C25H27FN8OS/c1-14-12-27-23-22-15-3-6-19(29-16(15)4-5-17(22)36-24(23)25(35)28-14)31-20-11-18(26)30-21(32-20)13-34-9-7-33(2)8-10-34/h3-6,11,14,27H,7-10,12-13H2,1-2H3,(H,28,35)(H,29,30,31,32)/t14-/m1/s1	VTCVFPKTUDXVRA-CQSZACIVSA-N	348822	US9790235, Number I-73	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348822&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936958	386050586							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689540	C[C@@H]1CNc2c(sc3ccc4nc(Nc5cc(F)nc(CN6CCCCC6)n5)ccc4c23)C(=O)N1	InChI=1S/C25H26FN7OS/c1-14-12-27-23-22-15-5-8-19(29-16(15)6-7-17(22)35-24(23)25(34)28-14)31-20-11-18(26)30-21(32-20)13-33-9-3-2-4-10-33/h5-8,11,14,27H,2-4,9-10,12-13H2,1H3,(H,28,34)(H,29,30,31,32)/t14-/m1/s1	MZEFLRWQGMLHRI-CQSZACIVSA-N	348823	US9790235, Number I-74	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348823&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936988	386050587							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689541	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc(n5)N(C)C)ccc4c23)C(=O)N1	InChI=1S/C20H18ClN7O2S/c1-9-8-22-15-14-10-4-7-13(30-20-26-18(21)25-19(27-20)28(2)3)24-11(10)5-6-12(14)31-16(15)17(29)23-9/h4-7,9,22H,8H2,1-3H3,(H,23,29)/t9-/m1/s1	CLDJCYUDBGCGMY-SECBINFHSA-N	348824	US9790235, Number I-75	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348824&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937015	386050588							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689542	COc1nc(Cl)nc(Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)n1	InChI=1S/C19H15ClN6O3S/c1-8-7-21-14-13-9-3-6-12(29-19-25-17(20)24-18(26-19)28-2)23-10(9)4-5-11(13)30-15(14)16(27)22-8/h3-6,8,21H,7H2,1-2H3,(H,22,27)/t8-/m1/s1	DHAOQLQJIZSIJI-MRVPVSSYSA-N	348825	US9790235, Number I-76	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348825&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937017	386050589							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689543	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cnnc(Cl)c5)ccc4c23)C(=O)N1	InChI=1S/C19H14ClN5O2S/c1-9-7-21-17-16-11-2-5-15(27-10-6-14(20)25-22-8-10)24-12(11)3-4-13(16)28-18(17)19(26)23-9/h2-6,8-9,21H,7H2,1H3,(H,23,26)/t9-/m1/s1	LLANQZXGLOZLFU-SECBINFHSA-N	348826	US9790235, Number I-79	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348826&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118943838	386050590							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689544	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN(C)C(C)(C)C)ccc4c23)C(=O)N1	InChI=1S/C25H27ClN6O2S/c1-13-10-27-20-19-15-6-9-18(30-16(15)7-8-17(19)35-21(20)22(33)29-13)34-23-14(11-28-24(26)31-23)12-32(5)25(2,3)4/h6-9,11,13,27H,10,12H2,1-5H3,(H,29,33)/t13-/m1/s1	BXAGSZRPCYRDDN-CYBMUJFWSA-N	348827	US9790235, Number I-80	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348827&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937010	386050591							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689545	COCCOCc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H22ClN5O4S/c1-12-9-25-19-18-14-3-6-17(28-15(14)4-5-16(18)34-20(19)21(30)27-12)33-22-13(10-26-23(24)29-22)11-32-8-7-31-2/h3-6,10,12,25H,7-9,11H2,1-2H3,(H,27,30)/t12-/m1/s1	UPUFEYJEHMSMAU-GFCCVEGCSA-N	348828	US9790235, Number I-81	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348828&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936951	386050592							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689546	CCOCc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H20ClN5O3S/c1-3-30-10-12-9-25-22(23)28-21(12)31-16-7-4-13-14(27-16)5-6-15-17(13)18-19(32-15)20(29)26-11(2)8-24-18/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1	PYOQIOLRFIRRSO-LLVKDONJSA-N	348829	US9790235, Number I-135::US9790235, Number I-82	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348829&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936948	386050593							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689547	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN5CC6CC6C5)ccc4c23)C(=O)N1	InChI=1S/C25H23ClN6O2S/c1-12-7-27-21-20-16-2-5-19(30-17(16)3-4-18(20)35-22(21)23(33)29-12)34-24-15(8-28-25(26)31-24)11-32-9-13-6-14(13)10-32/h2-5,8,12-14,27H,6-7,9-11H2,1H3,(H,29,33)/t12-,13?,14?/m1/s1	NZNFSWQZSNWIJE-IYXRBSQSSA-N	348830	US9790235, Number I-83	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348830&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936923	386050594							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689548	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CO[C@H]5CCOC5)ccc4c23)C(=O)N1	InChI=1S/C24H22ClN5O4S/c1-12-8-26-20-19-15-2-5-18(29-16(15)3-4-17(19)35-21(20)22(31)28-12)34-23-13(9-27-24(25)30-23)10-33-14-6-7-32-11-14/h2-5,9,12,14,26H,6-8,10-11H2,1H3,(H,28,31)/t12-,14+/m1/s1	JSOYBKCHGFRNIA-OCCSQVGLSA-N	348831	US9790235, Number I-84	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348831&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118943839	386050595							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689549	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN5CC6CC(C6)C5)ccc4c23)C(=O)N1	InChI=1S/C26H25ClN6O2S/c1-13-8-28-22-21-17-2-5-20(31-18(17)3-4-19(21)36-23(22)24(34)30-13)35-25-16(9-29-26(27)32-25)12-33-10-14-6-15(7-14)11-33/h2-5,9,13-15,28H,6-8,10-12H2,1H3,(H,30,34)/t13-,14?,15?/m1/s1	LJMUYVKQACXIFP-WLYUNCDWSA-N	348832	US9790235, Number I-85	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348832&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936897	386050596							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689550	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc6COCc56)ccc4c23)C(=O)N1	InChI=1S/C21H16ClN5O3S/c1-9-6-23-17-16-10-2-5-15(30-20-11-7-29-8-13(11)26-21(22)27-20)25-12(10)3-4-14(16)31-18(17)19(28)24-9/h2-5,9,23H,6-8H2,1H3,(H,24,28)/t9-/m1/s1	RWBXYPRAOZWOLX-SECBINFHSA-N	348833	US9790235, Number I-86	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348833&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936955	386050597							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689551	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(F)ncc5CN(C)C(C)(C)C)ccc4c23)C(=O)N1	InChI=1S/C25H27FN6O2S/c1-13-10-27-20-19-15-6-9-18(30-16(15)7-8-17(19)35-21(20)22(33)29-13)34-23-14(11-28-24(26)31-23)12-32(5)25(2,3)4/h6-9,11,13,27H,10,12H2,1-5H3,(H,29,33)/t13-/m1/s1	KGHQIDGOBDBPCV-CYBMUJFWSA-N	348834	US9790235, Number I-120::US9790235, Number I-87	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348834&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936953	386050598							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689552	CC(C)CN(CC(C)C)Cc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C28H33ClN6O2S/c1-15(2)12-35(13-16(3)4)14-18-11-31-28(29)34-27(18)37-22-9-6-19-20(33-22)7-8-21-23(19)24-25(38-21)26(36)32-17(5)10-30-24/h6-9,11,15-17,30H,10,12-14H2,1-5H3,(H,32,36)/t17-/m1/s1	RLEXYFMWEWRVRA-QGZVFWFLSA-N	348835	US9790235, Number I-88	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348835&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937031	386050599							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689553	COCC1CCCN1Cc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C26H27ClN6O3S/c1-14-10-28-22-21-17-5-8-20(31-18(17)6-7-19(21)37-23(22)24(34)30-14)36-25-15(11-29-26(27)32-25)12-33-9-3-4-16(33)13-35-2/h5-8,11,14,16,28H,3-4,9-10,12-13H2,1-2H3,(H,30,34)/t14-,16?/m1/s1	JVXBEOTZJXTVEE-IURRXHLWSA-N	348836	US9790235, Number I-89	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348836&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936972	386050600							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689554	COCCN(C)Cc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H25ClN6O3S/c1-13-10-26-20-19-15-4-7-18(29-16(15)5-6-17(19)35-21(20)22(32)28-13)34-23-14(11-27-24(25)30-23)12-31(2)8-9-33-3/h4-7,11,13,26H,8-10,12H2,1-3H3,(H,28,32)/t13-/m1/s1	AZVDQPXDQJRJLY-CYBMUJFWSA-N	348837	US9790235, Number I-90	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348837&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936900	386050601							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689555	CC(C)N(C)Cc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H25ClN6O2S/c1-12(2)31(4)11-14-10-27-24(25)30-23(14)33-18-8-5-15-16(29-18)6-7-17-19(15)20-21(34-17)22(32)28-13(3)9-26-20/h5-8,10,12-13,26H,9,11H2,1-4H3,(H,28,32)/t13-/m1/s1	GIPBOZMOWOAZDM-CYBMUJFWSA-N	348838	US9790235, Number I-91	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348838&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936996	386050602							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689556	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN(C)C5CCCCC5)ccc4c23)C(=O)N1	InChI=1S/C27H29ClN6O2S/c1-15-12-29-23-22-18-8-11-21(32-19(18)9-10-20(22)37-24(23)25(35)31-15)36-26-16(13-30-27(28)33-26)14-34(2)17-6-4-3-5-7-17/h8-11,13,15,17,29H,3-7,12,14H2,1-2H3,(H,31,35)/t15-/m1/s1	SDDLMLXRFFIOCS-OAHLLOKOSA-N	348839	US9790235, Number I-92	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348839&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936811	386050603							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689557	COC1CCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C26H27ClN6O3S/c1-14-11-28-22-21-17-3-6-20(31-18(17)4-5-19(21)37-23(22)24(34)30-14)36-25-15(12-29-26(27)32-25)13-33-9-7-16(35-2)8-10-33/h3-6,12,14,16,28H,7-11,13H2,1-2H3,(H,30,34)/t14-/m1/s1	LSHMLZHKOMGAGQ-CQSZACIVSA-N	348840	US9790235, Number I-132::US9790235, Number I-93	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348840&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936945	386050604							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689558	CCN1CCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C26H28ClN7O2S/c1-3-33-8-10-34(11-9-33)14-16-13-29-26(27)32-25(16)36-20-7-4-17-18(31-20)5-6-19-21(17)22-23(37-19)24(35)30-15(2)12-28-22/h4-7,13,15,28H,3,8-12,14H2,1-2H3,(H,30,35)/t15-/m1/s1	SMHCFHCHCNRWPY-OAHLLOKOSA-N	348841	US9790235, Number I-94	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348841&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936835	386050605							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689559	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN5CCCC(C)(C)C5)ccc4c23)C(=O)N1	InChI=1S/C27H29ClN6O2S/c1-15-11-29-22-21-17-5-8-20(32-18(17)6-7-19(21)37-23(22)24(35)31-15)36-25-16(12-30-26(28)33-25)13-34-10-4-9-27(2,3)14-34/h5-8,12,15,29H,4,9-11,13-14H2,1-3H3,(H,31,35)/t15-/m1/s1	IDABUBAEDYAPSE-OAHLLOKOSA-N	348842	US9790235, Number I-95	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348842&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936950	386050606							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689560	COCc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C21H18ClN5O3S/c1-10-7-23-17-16-12-3-6-15(30-20-11(9-29-2)8-24-21(22)27-20)26-13(12)4-5-14(16)31-18(17)19(28)25-10/h3-6,8,10,23H,7,9H2,1-2H3,(H,25,28)/t10-/m1/s1	DDQVZUCSSJJJPX-SNVBAGLBSA-N	348843	US9790235, Number I-96	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348843&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936888	386050607							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689561	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5COC(C)(C)C)ccc4c23)C(=O)N1	InChI=1S/C24H24ClN5O3S/c1-12-9-26-19-18-14-5-8-17(29-15(14)6-7-16(18)34-20(19)21(31)28-12)33-22-13(10-27-23(25)30-22)11-32-24(2,3)4/h5-8,10,12,26H,9,11H2,1-4H3,(H,28,31)/t12-/m1/s1	DCSISJZBRMFVLK-GFCCVEGCSA-N	348844	US9790235, Number I-97	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348844&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936819	386050608							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689562	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5COC5CCOCC5)ccc4c23)C(=O)N1	InChI=1S/C25H24ClN5O4S/c1-13-10-27-21-20-16-2-5-19(30-17(16)3-4-18(20)36-22(21)23(32)29-13)35-24-14(11-28-25(26)31-24)12-34-15-6-8-33-9-7-15/h2-5,11,13,15,27H,6-10,12H2,1H3,(H,29,32)/t13-/m1/s1	UIEMSJBKQPIURX-CYBMUJFWSA-N	348845	US9790235, Number I-98	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348845&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936891	386050609							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689563	C[C@@H]1CCCN1Cc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H25ClN6O2S/c1-13-10-27-21-20-16-5-8-19(30-17(16)6-7-18(20)35-22(21)23(33)29-13)34-24-15(11-28-25(26)31-24)12-32-9-3-4-14(32)2/h5-8,11,13-14,27H,3-4,9-10,12H2,1-2H3,(H,29,33)/t13-,14-/m1/s1	PXMJMXOZPVGOEX-ZIAGYGMSSA-N	348846	US9790235, Number I-99	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348846&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936920	386050610							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689564	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5COCCF)ccc4c23)C(=O)N1	InChI=1S/C22H19ClFN5O3S/c1-11-8-25-18-17-13-2-5-16(28-14(13)3-4-15(17)33-19(18)20(30)27-11)32-21-12(10-31-7-6-24)9-26-22(23)29-21/h2-5,9,11,25H,6-8,10H2,1H3,(H,27,30)/t11-/m1/s1	AIZPIDPRWMRNDM-LLVKDONJSA-N	348847	US9790235, Number I-100	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348847	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348847&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936816	386050611							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689565	C[C@H]1CCCN1Cc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H25ClN6O2S/c1-13-10-27-21-20-16-5-8-19(30-17(16)6-7-18(20)35-22(21)23(33)29-13)34-24-15(11-28-25(26)31-24)12-32-9-3-4-14(32)2/h5-8,11,13-14,27H,3-4,9-10,12H2,1-2H3,(H,29,33)/t13-,14+/m1/s1	PXMJMXOZPVGOEX-KGLIPLIRSA-N	348848	US9790235, Number I-101	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348848&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936959	386050612							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689566	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CNC(C)(C)C)ccc4c23)C(=O)N1	InChI=1S/C24H25ClN6O2S/c1-12-9-26-19-18-14-5-8-17(30-15(14)6-7-16(18)34-20(19)21(32)29-12)33-22-13(10-27-23(25)31-22)11-28-24(2,3)4/h5-8,10,12,26,28H,9,11H2,1-4H3,(H,29,32)/t12-/m1/s1	MTQHOWKZZNFZGT-GFCCVEGCSA-N	348849	US9790235, Number I-102	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348849&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936986	386050613							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689567	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5COC5(C)COC5)ccc4c23)C(=O)N1	InChI=1S/C24H22ClN5O4S/c1-12-7-26-19-18-14-3-6-17(29-15(14)4-5-16(18)35-20(19)21(31)28-12)34-22-13(8-27-23(25)30-22)9-33-24(2)10-32-11-24/h3-6,8,12,26H,7,9-11H2,1-2H3,(H,28,31)/t12-/m1/s1	OAWIWQKQAJPDRU-GFCCVEGCSA-N	348850	US9790235, Number I-103	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348850&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937011	386050614							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689568	C[C@@H]1CNc2c(sc3ccc4nc(Oc5ncncc5CN(C)C(C)(C)C)ccc4c23)C(=O)N1	InChI=1S/C25H28N6O2S/c1-14-10-27-21-20-16-6-9-19(30-17(16)7-8-18(20)34-22(21)23(32)29-14)33-24-15(11-26-13-28-24)12-31(5)25(2,3)4/h6-9,11,13-14,27H,10,12H2,1-5H3,(H,29,32)/t14-/m1/s1	DJOVGBOGNHQUJC-CQSZACIVSA-N	348851	US9790235, Number I-104	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348851&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936989	386050615							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689569	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc6CCS(=O)(=O)Cc56)ccc4c23)C(=O)N1	InChI=1S/C22H18ClN5O4S2/c1-10-8-24-18-17-11-2-5-16(26-13(11)3-4-15(17)33-19(18)20(29)25-10)32-21-12-9-34(30,31)7-6-14(12)27-22(23)28-21/h2-5,10,24H,6-9H2,1H3,(H,25,29)/t10-/m1/s1	ZCUGVUVSIXPMKZ-SNVBAGLBSA-N	348852	US9790235, Number I-105	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348852&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936965	386050616							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689570	CO[C@H]1CCCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C1	InChI=1S/C26H27ClN6O3S/c1-14-10-28-22-21-17-5-8-20(31-18(17)6-7-19(21)37-23(22)24(34)30-14)36-25-15(11-29-26(27)32-25)12-33-9-3-4-16(13-33)35-2/h5-8,11,14,16,28H,3-4,9-10,12-13H2,1-2H3,(H,30,34)/t14-,16+/m1/s1	HJVGCIZMOXPWEC-ZBFHGGJFSA-N	348853	US9790235, Number I-106	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348853	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348853&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936886	386050617							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689571	CO[C@@H]1CCCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C1	InChI=1S/C26H27ClN6O3S/c1-14-10-28-22-21-17-5-8-20(31-18(17)6-7-19(21)37-23(22)24(34)30-14)36-25-15(11-29-26(27)32-25)12-33-9-3-4-16(13-33)35-2/h5-8,11,14,16,28H,3-4,9-10,12-13H2,1-2H3,(H,30,34)/t14-,16-/m1/s1	HJVGCIZMOXPWEC-GDBMZVCRSA-N	348854	US9790235, Number I-107	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348854	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348854&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936894	386050618							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689572	CCOCCN(C)Cc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H27ClN6O3S/c1-4-34-10-9-32(3)13-15-12-28-25(26)31-24(15)35-19-8-5-16-17(30-19)6-7-18-20(16)21-22(36-18)23(33)29-14(2)11-27-21/h5-8,12,14,27H,4,9-11,13H2,1-3H3,(H,29,33)/t14-/m1/s1	BVEMSYVDIREACR-CQSZACIVSA-N	348855	US9790235, Number I-108	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348855	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348855&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937048	386050619							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689573	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc6CCCCc56)ccc4c23)C(=O)N1	InChI=1S/C23H20ClN5O2S/c1-11-10-25-19-18-12-6-9-17(27-15(12)7-8-16(18)32-20(19)21(30)26-11)31-22-13-4-2-3-5-14(13)28-23(24)29-22/h6-9,11,25H,2-5,10H2,1H3,(H,26,30)/t11-/m1/s1	NZZNEILQTNHBBX-LLVKDONJSA-N	348856	US9790235, Number I-109	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348856	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348856&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937002	386050620							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689574	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5COCC(F)F)ccc4c23)C(=O)N1	InChI=1S/C22H18ClF2N5O3S/c1-10-6-26-18-17-12-2-5-16(29-13(12)3-4-14(17)34-19(18)20(31)28-10)33-21-11(7-27-22(23)30-21)8-32-9-15(24)25/h2-5,7,10,15,26H,6,8-9H2,1H3,(H,28,31)/t10-/m1/s1	NZEBXRUNHXMTRL-SNVBAGLBSA-N	348857	US9790235, Number I-110	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348857	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348857&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937036	386050621							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689575	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5COCCC#N)ccc4c23)C(=O)N1	InChI=1S/C23H19ClN6O3S/c1-12-9-26-19-18-14-3-6-17(29-15(14)4-5-16(18)34-20(19)21(31)28-12)33-22-13(10-27-23(24)30-22)11-32-8-2-7-25/h3-6,10,12,26H,2,8-9,11H2,1H3,(H,28,31)/t12-/m1/s1	OJEKLJRFIVDLNH-GFCCVEGCSA-N	348858	US9790235, Number I-111	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348858	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348858&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936976	386050622							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689576	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CS(C)(=O)=O)ccc4c23)C(=O)N1	InChI=1S/C21H18ClN5O4S2/c1-10-7-23-17-16-12-3-6-15(26-13(12)4-5-14(16)32-18(17)19(28)25-10)31-20-11(9-33(2,29)30)8-24-21(22)27-20/h3-6,8,10,23H,7,9H2,1-2H3,(H,25,28)/t10-/m1/s1	CNYJSZLEHVVWIM-SNVBAGLBSA-N	348859	US9790235, Number I-112	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348859	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348859&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936875	386050623							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689577	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5COC(F)F)ccc4c23)C(=O)N1	InChI=1S/C21H16ClF2N5O3S/c1-9-6-25-16-15-11-2-5-14(28-12(11)3-4-13(15)33-17(16)18(30)27-9)32-19-10(8-31-21(23)24)7-26-20(22)29-19/h2-5,7,9,21,25H,6,8H2,1H3,(H,27,30)/t9-/m1/s1	KRKBKEKSTQWSNJ-SECBINFHSA-N	348860	US9790235, Number I-113	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348860&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936949	386050624							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689578	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN5C6CCC5COC6)ccc4c23)C(=O)N1	InChI=1S/C26H25ClN6O3S/c1-13-8-28-22-21-17-4-7-20(31-18(17)5-6-19(21)37-23(22)24(34)30-13)36-25-14(9-29-26(27)32-25)10-33-15-2-3-16(33)12-35-11-15/h4-7,9,13,15-16,28H,2-3,8,10-12H2,1H3,(H,30,34)/t13-,15?,16?/m1/s1	JVUMCOJVNRSVNP-IUDNXUCKSA-N	348861	US9790235, Number I-114	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348861&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936934	386050625							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689579	C[C@H]1CN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C[C@@H](C)N1	InChI=1S/C26H28ClN7O2S/c1-13-8-28-22-21-17-4-7-20(32-18(17)5-6-19(21)37-23(22)24(35)31-13)36-25-16(9-29-26(27)33-25)12-34-10-14(2)30-15(3)11-34/h4-7,9,13-15,28,30H,8,10-12H2,1-3H3,(H,31,35)/t13-,14-,15+/m1/s1	LUAXLSNPMHBUHR-KFWWJZLASA-N	348862	US9790235, Number I-115	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348862&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936971	386050626							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689580	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5Br)ccc4c23)C(=O)N1	InChI=1S/C19H13BrClN5O2S/c1-8-6-22-15-14-9-2-5-13(28-18-10(20)7-23-19(21)26-18)25-11(9)3-4-12(14)29-16(15)17(27)24-8/h2-5,7-8,22H,6H2,1H3,(H,24,27)/t8-/m1/s1	YHZFUHUOOZQFRM-MRVPVSSYSA-N	348863	US9790235, Number I-116	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348863&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936992	386050627							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689581	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cc(CNC(C)(C)C)nc(Cl)n5)ccc4c23)C(=O)N1	InChI=1S/C24H25ClN6O2S/c1-12-10-26-20-19-14-5-8-17(30-15(14)6-7-16(19)34-21(20)22(32)28-12)33-18-9-13(29-23(25)31-18)11-27-24(2,3)4/h5-9,12,26-27H,10-11H2,1-4H3,(H,28,32)/t12-/m1/s1	RBIYSEAHGKWJDG-GFCCVEGCSA-N	348864	US9790235, Number I-117	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348864&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936871	386050628							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689582	C[C@@H]1CNc2c(sc3ccc4nc(Oc5cc(CN(C)C(C)(C)C)nc(Cl)n5)ccc4c23)C(=O)N1	InChI=1S/C25H27ClN6O2S/c1-13-11-27-21-20-15-6-9-18(30-16(15)7-8-17(20)35-22(21)23(33)28-13)34-19-10-14(29-24(26)31-19)12-32(5)25(2,3)4/h6-10,13,27H,11-12H2,1-5H3,(H,28,33)/t13-/m1/s1	XAMXPLHGOXKZFT-CYBMUJFWSA-N	348865	US9790235, Number I-118	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348865&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936904	386050629							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689583	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(F)nc6COCc56)ccc4c23)C(=O)N1	InChI=1S/C21H16FN5O3S/c1-9-6-23-17-16-10-2-5-15(30-20-11-7-29-8-13(11)26-21(22)27-20)25-12(10)3-4-14(16)31-18(17)19(28)24-9/h2-5,9,23H,6-8H2,1H3,(H,24,28)/t9-/m1/s1	VXIMZPFOJNTHBL-SECBINFHSA-N	348866	US9790235, Number I-119	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348866&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937045	386050630							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689584	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(F)ncc5CN(C)C(C)(C)C)ccc4c23)C(=O)N1	InChI=1S/C25H27FN6O2S/c1-13-10-27-20-19-15-6-9-18(30-16(15)7-8-17(19)35-21(20)22(33)29-13)34-23-14(11-28-24(26)31-23)12-32(5)25(2,3)4/h6-9,11,13,27H,10,12H2,1-5H3,(H,29,33)/t13-/m1/s1	KGHQIDGOBDBPCV-CYBMUJFWSA-N	348834	US9790235, Number I-120::US9790235, Number I-87	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348834&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936953	386050598							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689585	CCOCc1cnc(F)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H20FN5O3S/c1-3-30-10-12-9-25-22(23)28-21(12)31-16-7-4-13-14(27-16)5-6-15-17(13)18-19(32-15)20(29)26-11(2)8-24-18/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1	UJGAASKGPUZGIA-LLVKDONJSA-N	348868	US9790235, Number I-121	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348868&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936840	386050631							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689586	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5C5=CCN(C)CC5)ccc4c23)C(=O)N1	InChI=1S/C25H23ClN6O2S/c1-13-11-27-21-20-15-3-6-19(30-17(15)4-5-18(20)35-22(21)23(33)29-13)34-24-16(12-28-25(26)31-24)14-7-9-32(2)10-8-14/h3-7,12-13,27H,8-11H2,1-2H3,(H,29,33)/t13-/m1/s1	GGRVHLKSLQGTLJ-CYBMUJFWSA-N	348869	US9790235, Number I-122	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348869&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937044	386050632							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689587	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5-c5cccnc5)ccc4c23)C(=O)N1	InChI=1S/C24H17ClN6O2S/c1-12-9-27-20-19-14-4-7-18(30-16(14)5-6-17(19)34-21(20)22(32)29-12)33-23-15(11-28-24(25)31-23)13-3-2-8-26-10-13/h2-8,10-12,27H,9H2,1H3,(H,29,32)/t12-/m1/s1	WZZFAHNHSXLEDK-GFCCVEGCSA-N	348870	US9790235, Number I-123	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348870&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936982	386050633							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689588	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5C5=CCOCC5)ccc4c23)C(=O)N1	InChI=1S/C24H20ClN5O3S/c1-12-10-26-20-19-14-2-5-18(29-16(14)3-4-17(19)34-21(20)22(31)28-12)33-23-15(11-27-24(25)30-23)13-6-8-32-9-7-13/h2-6,11-12,26H,7-10H2,1H3,(H,28,31)/t12-/m1/s1	OUTSQWFHNHRBCJ-GFCCVEGCSA-N	348871	US9790235, Number I-124	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348871&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937034	386050634							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689589	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc6CCNCc56)ccc4c23)C(=O)N1	InChI=1S/C22H19ClN6O2S/c1-10-8-25-18-17-11-2-5-16(27-13(11)3-4-15(17)32-19(18)20(30)26-10)31-21-12-9-24-7-6-14(12)28-22(23)29-21/h2-5,10,24-25H,6-9H2,1H3,(H,26,30)/t10-/m1/s1	PCJNNKDZFGZCDG-SNVBAGLBSA-N	348872	US9790235, Number I-125	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348872&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936941	386050635							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689590	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)nc6CCN(C)Cc56)ccc4c23)C(=O)N1	InChI=1S/C23H21ClN6O2S/c1-11-9-25-19-18-12-3-6-17(27-14(12)4-5-16(18)33-20(19)21(31)26-11)32-22-13-10-30(2)8-7-15(13)28-23(24)29-22/h3-6,11,25H,7-10H2,1-2H3,(H,26,31)/t11-/m1/s1	JVHOZUXGNLRJCA-LLVKDONJSA-N	348873	US9790235, Number I-126	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348873&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936892	386050636							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689591	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CO)ccc4c23)C(=O)N1	InChI=1S/C20H16ClN5O3S/c1-9-6-22-16-15-11-2-5-14(29-19-10(8-27)7-23-20(21)26-19)25-12(11)3-4-13(15)30-17(16)18(28)24-9/h2-5,7,9,22,27H,6,8H2,1H3,(H,24,28)/t9-/m1/s1	PJUGIHAOHKLRPM-SECBINFHSA-N	348874	US9790235, Number I-127	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348874&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936889	386050637							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689592	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN5CCC(O)CC5)ccc4c23)C(=O)N1	InChI=1S/C25H25ClN6O3S/c1-13-10-27-21-20-16-2-5-19(30-17(16)3-4-18(20)36-22(21)23(34)29-13)35-24-14(11-28-25(26)31-24)12-32-8-6-15(33)7-9-32/h2-5,11,13,15,27,33H,6-10,12H2,1H3,(H,29,34)/t13-/m1/s1	HVERKHCNHSHVFH-CYBMUJFWSA-N	348875	US9790235, Number I-128	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348875&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936869	386050638							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689593	CCOC1CCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C27H29ClN6O3S/c1-3-36-17-8-10-34(11-9-17)14-16-13-30-27(28)33-26(16)37-21-7-4-18-19(32-21)5-6-20-22(18)23-24(38-20)25(35)31-15(2)12-29-23/h4-7,13,15,17,29H,3,8-12,14H2,1-2H3,(H,31,35)/t15-/m1/s1	IMILFOWPONBYRO-OAHLLOKOSA-N	348876	US9790235, Number I-129	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348876&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937022	386050639							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689594	COCCOC1CCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C28H31ClN6O4S/c1-16-13-30-24-23-19-3-6-22(33-20(19)4-5-21(23)40-25(24)26(36)32-16)39-27-17(14-31-28(29)34-27)15-35-9-7-18(8-10-35)38-12-11-37-2/h3-6,14,16,18,30H,7-13,15H2,1-2H3,(H,32,36)/t16-/m1/s1	MIQPDXAHEUYPOD-MRXNPFEDSA-N	348877	US9790235, Number I-130	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348877&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118937004	386050640							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689595	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN5CCC(CC5)OCCF)ccc4c23)C(=O)N1	InChI=1S/C27H28ClFN6O3S/c1-15-12-30-23-22-18-2-5-21(33-19(18)3-4-20(22)39-24(23)25(36)32-15)38-26-16(13-31-27(28)34-26)14-35-9-6-17(7-10-35)37-11-8-29/h2-5,13,15,17,30H,6-12,14H2,1H3,(H,32,36)/t15-/m1/s1	DIZIEKQMCRPZBZ-OAHLLOKOSA-N	348878	US9790235, Number I-131	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348878&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936954	386050641							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689596	COC1CCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C26H27ClN6O3S/c1-14-11-28-22-21-17-3-6-20(31-18(17)4-5-19(21)37-23(22)24(34)30-14)36-25-15(12-29-26(27)32-25)13-33-9-7-16(35-2)8-10-33/h3-6,12,14,16,28H,7-11,13H2,1-2H3,(H,30,34)/t14-/m1/s1	LSHMLZHKOMGAGQ-CQSZACIVSA-N	348840	US9790235, Number I-132::US9790235, Number I-93	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348840&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936945	386050604							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689597	CC(C)OC1CCN(Cc2cnc(Cl)nc2Oc2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C28H31ClN6O3S/c1-15(2)37-18-8-10-35(11-9-18)14-17-13-31-28(29)34-27(17)38-22-7-4-19-20(33-22)5-6-21-23(19)24-25(39-21)26(36)32-16(3)12-30-24/h4-7,13,15-16,18,30H,8-12,14H2,1-3H3,(H,32,36)/t16-/m1/s1	SZEKWCVBNLGUPW-MRXNPFEDSA-N	348880	US9790235, Number I-133	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348880&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936845	386050642							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689598	C[C@@H]1CNc2c(sc3ccc4nc(Oc5nc(Cl)ncc5CN5CCC(CC5)OC(C)(C)C)ccc4c23)C(=O)N1	InChI=1S/C29H33ClN6O3S/c1-16-13-31-24-23-19-5-8-22(34-20(19)6-7-21(23)40-25(24)26(37)33-16)38-27-17(14-32-28(30)35-27)15-36-11-9-18(10-12-36)39-29(2,3)4/h5-8,14,16,18,31H,9-13,15H2,1-4H3,(H,33,37)/t16-/m1/s1	HDBVIMRLICNIHN-MRXNPFEDSA-N	348881	US9790235, Number I-134	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348881&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936906	386050643							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
689599	CCOCc1cnc(Cl)nc1Oc1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H20ClN5O3S/c1-3-30-10-12-9-25-22(23)28-21(12)31-16-7-4-13-14(27-16)5-6-15-17(13)18-19(32-15)20(29)26-11(2)8-24-18/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1	PYOQIOLRFIRRSO-LLVKDONJSA-N	348829	US9790235, Number I-135::US9790235, Number I-82	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2NZ89RS		aid1797407	US9790235	Alexander, MD; Chuaqui, C; Malona, J; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Singh, J; Pabba, C	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=348829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=348829&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118936948	386050593							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51135035	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(c(F)c4-c3[nH]c21)-c1cccc(F)c1	InChI=1S/C23H20F2N4O/c1-29-10-23(11-29)9-27-22(30)17-15-6-5-13-8-26-19(12-3-2-4-14(24)7-12)18(25)16(13)20(15)28-21(17)23/h2-4,7-8,28H,5-6,9-11H2,1H3,(H,27,30)	HZYGUYMZIQSDQB-UHFFFAOYSA-N	50465453	CHEMBL4277929	MAP kinase-activated protein kinase 2	Homo sapiens		 370							ChEMBL	10.1021/acsmedchemlett.8b00098	10.7270/Q2VX0K5Z	29670707			Velcicky, J; Schlapbach, A; Heng, R; Revesz, L; Pflieger, D; Blum, E; Hawtin, S; Huppertz, C; Feifel, R; Hersperger, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465453&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			138978963	433932718							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51135036	COc1ccc(cn1)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CN(C)C3)-c2c1F	InChI=1S/C23H22FN5O2/c1-29-10-23(11-29)9-27-22(30)17-14-5-3-12-7-26-19(13-4-6-15(31-2)25-8-13)18(24)16(12)20(14)28-21(17)23/h4,6-8,28H,3,5,9-11H2,1-2H3,(H,27,30)	LTPHDFADTLLZOP-UHFFFAOYSA-N	50465454	CHEMBL4293121	MAP kinase-activated protein kinase 2	Homo sapiens		 480							ChEMBL	10.1021/acsmedchemlett.8b00098	10.7270/Q2VX0K5Z	29670707			Velcicky, J; Schlapbach, A; Heng, R; Revesz, L; Pflieger, D; Blum, E; Hawtin, S; Huppertz, C; Feifel, R; Hersperger, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465454&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			145989661	433932719							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51135037	COc1ccc(cc1F)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CN(C)C3)-c2c1F	InChI=1S/C24H22F2N4O2/c1-30-10-24(11-30)9-28-23(31)18-14-5-3-13-8-27-20(12-4-6-16(32-2)15(25)7-12)19(26)17(13)21(14)29-22(18)24/h4,6-8,29H,3,5,9-11H2,1-2H3,(H,28,31)	DCJFWTATDIDOFA-UHFFFAOYSA-N	50465455	CHEMBL4282514	MAP kinase-activated protein kinase 2	Homo sapiens		 370							ChEMBL	10.1021/acsmedchemlett.8b00098	10.7270/Q2VX0K5Z	29670707			Velcicky, J; Schlapbach, A; Heng, R; Revesz, L; Pflieger, D; Blum, E; Hawtin, S; Huppertz, C; Feifel, R; Hersperger, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465455&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			145979306	433932720							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51135038	COc1ccc(cc1F)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CN(C)C3)-c2c1F	InChI=1S/C24H22F2N4O2/c1-30-10-24(11-30)9-28-23(31)18-14-5-3-13-8-27-20(12-4-6-16(32-2)15(25)7-12)19(26)17(13)21(14)29-22(18)24/h4,6-8,29H,3,5,9-11H2,1-2H3,(H,28,31)	DCJFWTATDIDOFA-UHFFFAOYSA-N	50465455	CHEMBL4282514	MAP kinase-activated protein kinase 2	Homo sapiens		<3.0							ChEMBL	10.1021/acsmedchemlett.8b00098	10.7270/Q2VX0K5Z	29670707			Velcicky, J; Schlapbach, A; Heng, R; Revesz, L; Pflieger, D; Blum, E; Hawtin, S; Huppertz, C; Feifel, R; Hersperger, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465455&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			145979306	433932720							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51135039	CN1CC2(C1)CNC(=O)c1c3CCc4cnc(c(F)c4-c3[nH]c21)-c1cccc(F)c1	InChI=1S/C23H20F2N4O/c1-29-10-23(11-29)9-27-22(30)17-15-6-5-13-8-26-19(12-3-2-4-14(24)7-12)18(25)16(13)20(15)28-21(17)23/h2-4,7-8,28H,5-6,9-11H2,1H3,(H,27,30)	HZYGUYMZIQSDQB-UHFFFAOYSA-N	50465453	CHEMBL4277929	MAP kinase-activated protein kinase 2	Homo sapiens		<3.0							ChEMBL	10.1021/acsmedchemlett.8b00098	10.7270/Q2VX0K5Z	29670707			Velcicky, J; Schlapbach, A; Heng, R; Revesz, L; Pflieger, D; Blum, E; Hawtin, S; Huppertz, C; Feifel, R; Hersperger, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465453&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			138978963	433932718							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51135040	COc1ccc(cn1)-c1ncc2CCc3c([nH]c4c3C(=O)NCC43CN(C)C3)-c2c1F	InChI=1S/C23H22FN5O2/c1-29-10-23(11-29)9-27-22(30)17-14-5-3-12-7-26-19(13-4-6-15(31-2)25-8-13)18(24)16(12)20(14)28-21(17)23/h4,6-8,28H,3,5,9-11H2,1-2H3,(H,27,30)	LTPHDFADTLLZOP-UHFFFAOYSA-N	50465454	CHEMBL4293121	MAP kinase-activated protein kinase 2	Homo sapiens		<3.0							ChEMBL	10.1021/acsmedchemlett.8b00098	10.7270/Q2VX0K5Z	29670707			Velcicky, J; Schlapbach, A; Heng, R; Revesz, L; Pflieger, D; Blum, E; Hawtin, S; Huppertz, C; Feifel, R; Hersperger, R	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50465454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50465454&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			145989661	433932719							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51128180	O=C(Cc1cccc(OCCCN2CCNCC2)c1)Nc1nc(cs1)-c1ccncc1	InChI=1S/C23H27N5O2S/c29-22(27-23-26-21(17-31-23)19-5-7-24-8-6-19)16-18-3-1-4-20(15-18)30-14-2-11-28-12-9-25-10-13-28/h1,3-8,15,17,25H,2,9-14,16H2,(H,26,27,29)	XLMFBNMLEHYJGT-UHFFFAOYSA-N	50462709	CHEMBL4245507	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL	10.1016/j.bmcl.2018.06.043	10.7270/Q2XP77MH	29945794			Gao, H; Marhefka, C; Jacobs, MD; Cao, J; Bandarage, UK; Green, J	Vertex Pharmaceuticals, Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50462709	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50462709&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			60097495	433929974							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51130345	CS(=O)(=O)Nc1cccc(CC(=O)Nc2nc(cs2)-c2c[nH]c3ncccc23)c1	InChI=1S/C19H17N5O3S2/c1-29(26,27)24-13-5-2-4-12(8-13)9-17(25)23-19-22-16(11-28-19)15-10-21-18-14(15)6-3-7-20-18/h2-8,10-11,24H,9H2,1H3,(H,20,21)(H,22,23,25)	HIUHVDROHDSKTC-UHFFFAOYSA-N	50463479	CHEMBL4249925	MAP kinase-activated protein kinase 2	Homo sapiens	>2000								ChEMBL	10.1016/j.bmcl.2018.06.040	10.7270/Q2ZC85HX	30082069			Bandarage, UK; Cao, J; Come, JH; Court, JJ; Gao, H; Jacobs, MD; Marhefka, C; Nanthakumar, S; Green, J	Vertex Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463479&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	6U1	5KKS	11690457	433930744							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51130368	O=C(Cc1cccc(OCCCC2CCNCC2)c1)Nc1nc(cs1)-c1c[nH]c2ncccc12	InChI=1S/C26H29N5O2S/c32-24(31-26-30-23(17-34-26)22-16-29-25-21(22)7-2-10-28-25)15-19-4-1-6-20(14-19)33-13-3-5-18-8-11-27-12-9-18/h1-2,4,6-7,10,14,16-18,27H,3,5,8-9,11-13,15H2,(H,28,29)(H,30,31,32)	OKUPZBPYLVKVSU-UHFFFAOYSA-N	50463483	CHEMBL4245242	MAP kinase-activated protein kinase 2	Homo sapiens	>2000								ChEMBL	10.1016/j.bmcl.2018.06.040	10.7270/Q2ZC85HX	30082069			Bandarage, UK; Cao, J; Come, JH; Court, JJ; Gao, H; Jacobs, MD; Marhefka, C; Nanthakumar, S; Green, J	Vertex Pharmaceuticals Inc	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50463483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50463483&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	504	5UZK	11561968	433930748							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51215881	OC(=O)C1CN(Cc2ccc(OCc3ccc(Cl)c(Cl)c3)cc2)C1	InChI=1S/C18H17Cl2NO3/c19-16-6-3-13(7-17(16)20)11-24-15-4-1-12(2-5-15)8-21-9-14(10-21)18(22)23/h1-7,14H,8-11H2,(H,22,23)	WAAWETUDFSIYSD-UHFFFAOYSA-N	50499634	CHEMBL3741589	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.5b00928	10.7270/Q2PZ5CV4	26509640			Hobson, AD; Harris, CM; van der Kam, EL; Turner, SC; Abibi, A; Aguirre, AL; Bousquet, P; Kebede, T; Konopacki, DB; Gintant, G; Kim, Y; Larson, K; Maull, JW; Moore, NS; Shi, D; Shrestha, A; Tang, X; Zhang, P; Sarris, KK	AbbVie Bioresearch Center	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50499634	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50499634&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			46872626	433911535							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51217235	C[C@@H]1C[C@H](N)C[C@@H](C1)c1ccncc1NC(=O)c1ccc(F)c(n1)-c1c(F)cccc1F	InChI=1S/C24H23F3N4O/c1-13-9-14(11-15(28)10-13)16-7-8-29-12-21(16)31-24(32)20-6-5-19(27)23(30-20)22-17(25)3-2-4-18(22)26/h2-8,12-15H,9-11,28H2,1H3,(H,31,32)/t13-,14+,15-/m0/s1	VRQXRVAKPDCRCI-ZNMIVQPWSA-N	106870	US8592455, 70	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1021/acs.jmedchem.5b01275	10.7270/Q2H41VGN	26505898			Burger, MT; Nishiguchi, G; Han, W; Lan, J; Simmons, R; Atallah, G; Ding, Y; Tamez, V; Zhang, Y; Mathur, M; Muller, K; Bellamacina, C; Lindvall, MK; Zang, R; Huh, K; Feucht, P; Zavorotinskaya, T; Dai, Y; Basham, S; Chan, J; Ginn, E; Aycinena, A; Holash, J; Castillo, J; Langowski, JL; Wang, Y; Chen, MY; Lambert, A; Fritsch, C; Kauffmann, A; Pfister, E; Vanasse, KG; Garcia, PD	Novartis Institutes for Biomedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=106870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=106870&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	5H7	5DWR	44814409	174009181						ZINC96177711	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51222473	CC(C)n1c(C)nc2c(F)cc(cc12)-c1nc(Nc2ccc3CN(CCN(C)C)CCc3n2)ncc1F	InChI=1S/C27H32F2N8/c1-16(2)37-17(3)31-26-20(28)12-19(13-23(26)37)25-21(29)14-30-27(34-25)33-24-7-6-18-15-36(11-10-35(4)5)9-8-22(18)32-24/h6-7,12-14,16H,8-11,15H2,1-5H3,(H,30,32,33,34)	KGMVZSJAPXYTKH-UHFFFAOYSA-N	444543	US10662186, Compound 63::US10988476, Compound I-63	MAP kinase-activated protein kinase 2	Homo sapiens		>30000							ChEMBL	10.1016/j.ejmech.2019.06.005	10.7270/Q20K2CTJ	31200237			Shi, C; Wang, Q; Liao, X; Ge, H; Huo, G; Zhang, L; Chen, N; Zhai, X; Hong, Y; Wang, L; Han, Y; Xiao, W; Wang, Z; Shi, W; Mao, Y; Yu, J; Xia, G; Liu, Y	Shanghai Pharmaceuticals Holding Co., Ltd.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=444543	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=444543&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			130196825	440706790							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51246735	COC[C@@H](C)Nc1cc(NC(=O)N2CCCc3cc(CN4CCCCOC4=O)c(C=O)nc23)ncc1C#N	InChI=1S/C26H31N7O5/c1-17(16-37-2)29-21-11-23(28-13-20(21)12-27)31-25(35)33-8-5-6-18-10-19(22(15-34)30-24(18)33)14-32-7-3-4-9-38-26(32)36/h10-11,13,15,17H,3-9,14,16H2,1-2H3,(H2,28,29,31,35)/t17-/m1/s1	KKJMPXBLFLQRJJ-QGZVFWFLSA-N	50509949	CHEMBL4475216::US11667631, Example 29	MAP kinase-activated protein kinase 2	Homo sapiens		>10000							ChEMBL	10.1016/j.bmc.2019.04.018	10.7270/Q2SB491W	30987781			Sun, C; Fang, L; Zhang, X; Gao, P; Gou, S	Southeast University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50509949	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50509949&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			132156633	440718534							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51238634	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	MAP kinase-activated protein kinase 2	Homo sapiens		 128							ChEMBL	10.1016/j.ejmech.2018.10.052	10.7270/Q2W380MT	30384048			Narayan, S; Ramisetti, S; Jaiswal, AS; Law, BK; Singh-Pillay, A; Singh, P; Amin, S; Sharma, AK	University of Florida	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51326458	Cn1cc(cn1)-c1cnc2c(cnn2c1)-c1csc(c1)C(=O)NCC(F)(F)F	InChI=1S/C17H13F3N6OS/c1-25-6-12(4-23-25)11-3-21-15-13(5-24-26(15)7-11)10-2-14(28-8-10)16(27)22-9-17(18,19)20/h2-8H,9H2,1H3,(H,22,27)	UEFCSGDOOJJXTN-UHFFFAOYSA-N	50536678	CHEMBL4550702	MAP kinase-activated protein kinase 2	Homo sapiens		>100000							ChEMBL	10.1016/j.bmcl.2016.02.003	10.7270/Q2NP27X5	27491711			Sloman, DL; Noucti, N; Altman, MD; Chen, D; Mislak, AC; Szewczak, A; Hayashi, M; Warren, L; Dellovade, T; Wu, Z; Marcus, J; Walker, D; Su, HP; Edavettal, SC; Munshi, S; Hutton, M; Nuthall, H; Stanton, MG	Merck and Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50536678	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50536678&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			59603829	440827502							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51326534	FC(F)(F)CNC(=O)c1cc(cs1)-c1cnn2cc(cnc12)-c1ccc(OCCN2CCCCC2)cc1	InChI=1S/C26H26F3N5O2S/c27-26(28,29)17-31-25(35)23-12-19(16-37-23)22-14-32-34-15-20(13-30-24(22)34)18-4-6-21(7-5-18)36-11-10-33-8-2-1-3-9-33/h4-7,12-16H,1-3,8-11,17H2,(H,31,35)	QNABDSWBQJKBHK-UHFFFAOYSA-N	50536675	CHEMBL4569508	MAP kinase-activated protein kinase 2	Homo sapiens		 55000							ChEMBL	10.1016/j.bmcl.2016.02.003	10.7270/Q2NP27X5	27491711			Sloman, DL; Noucti, N; Altman, MD; Chen, D; Mislak, AC; Szewczak, A; Hayashi, M; Warren, L; Dellovade, T; Wu, Z; Marcus, J; Walker, D; Su, HP; Edavettal, SC; Munshi, S; Hutton, M; Nuthall, H; Stanton, MG	Merck and Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50536675	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50536675&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24759534	440827499							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51326588	Cc1sc(cc1-c1cnn2cc(Cl)cnc12)C(=O)N[C@@H]1[C@H](N)CCCC1(F)F	InChI=1S/C18H18ClF2N5OS/c1-9-11(12-7-24-26-8-10(19)6-23-16(12)26)5-14(28-9)17(27)25-15-13(22)3-2-4-18(15,20)21/h5-8,13,15H,2-4,22H2,1H3,(H,25,27)/t13-,15-/m1/s1	NGFGTMFVWSDFPS-UKRRQHHQSA-N	50536681	CHEMBL4552628	MAP kinase-activated protein kinase 2	Homo sapiens		 7800							ChEMBL	10.1016/j.bmcl.2016.02.003	10.7270/Q2NP27X5	27491711			Sloman, DL; Noucti, N; Altman, MD; Chen, D; Mislak, AC; Szewczak, A; Hayashi, M; Warren, L; Dellovade, T; Wu, Z; Marcus, J; Walker, D; Su, HP; Edavettal, SC; Munshi, S; Hutton, M; Nuthall, H; Stanton, MG	Merck and Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50536681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50536681&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			89735655	440827505							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51326334	Cn1cc(cn1)-c1cnc2c(cnn2c1)-c1csc(c1)C(=O)N[C@@H]1CCCC[C@@H]1N	InChI=1S/C21H23N7OS/c1-27-10-15(8-24-27)14-7-23-20-16(9-25-28(20)11-14)13-6-19(30-12-13)21(29)26-18-5-3-2-4-17(18)22/h6-12,17-18H,2-5,22H2,1H3,(H,26,29)/t17-,18+/m0/s1	LYADGAGFYYXXIO-ZWKOTPCHSA-N	50536679	CHEMBL4568087	MAP kinase-activated protein kinase 2	Homo sapiens		 390							ChEMBL	10.1016/j.bmcl.2016.02.003	10.7270/Q2NP27X5	27491711			Sloman, DL; Noucti, N; Altman, MD; Chen, D; Mislak, AC; Szewczak, A; Hayashi, M; Warren, L; Dellovade, T; Wu, Z; Marcus, J; Walker, D; Su, HP; Edavettal, SC; Munshi, S; Hutton, M; Nuthall, H; Stanton, MG	Merck and Co.	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50536679	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50536679&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			59603842	440827503							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081954	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C24H19FN4O2S/c1-3-20(30)29-18-10-13(4-6-15(18)25)16-7-5-14-17(28-16)8-9-19-21(14)22-23(32-19)24(31)27-12(2)11-26-22/h3-10,12,26H,1,11H2,2H3,(H,27,31)(H,29,30)/t12-/m1/s1	XOPLVPJXKXPRDF-GFCCVEGCSA-N	515429	US11098061, Compound III-13	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515429&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611320	461601537							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081955	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C24H19FN4O2S/c1-3-20(30)29-18-10-13(4-6-15(18)25)16-7-5-14-17(28-16)8-9-19-21(14)22-23(32-19)24(31)27-12(2)11-26-22/h3-10,12,26H,1,11H2,2H3,(H,27,31)(H,29,30)/t12-/m1/s1	XOPLVPJXKXPRDF-GFCCVEGCSA-N	515429	US11098061, Compound III-13	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515429	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515429&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611320	461601537							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081956	COCCOc1ccc(cc1NC(=O)C=C)-c1cc(ccn1)-c1cc2NC[C@@H](C)NC(=O)c2s1	InChI=1S/C25H26N4O4S/c1-4-23(30)29-19-11-16(5-6-21(19)33-10-9-32-3)18-12-17(7-8-26-18)22-13-20-24(34-22)25(31)28-15(2)14-27-20/h4-8,11-13,15,27H,1,9-10,14H2,2-3H3,(H,28,31)(H,29,30)/t15-/m1/s1	FHRVHZIRJWAISW-OAHLLOKOSA-N	515430	US11098061, Compound III-d-1	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515430	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515430&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301505	461601538							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081957	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(OCCN(C)C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C26H29N5O4S/c1-5-22(32)30-19-13-17(7-8-20(19)35-11-10-31(3)4)29-25(33)16-6-9-21-18(12-16)23-24(36-21)26(34)28-15(2)14-27-23/h5-9,12-13,15,27H,1,10-11,14H2,2-4H3,(H,28,34)(H,29,33)(H,30,32)/t15-/m1/s1	ZJJPMWGHGIMGCI-OAHLLOKOSA-N	515431	US11098061, Compound III-35	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515431&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611125	461601539							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081958	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(OCCN(C)C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C26H29N5O4S/c1-5-22(32)30-19-13-17(7-8-20(19)35-11-10-31(3)4)29-25(33)16-6-9-21-18(12-16)23-24(36-21)26(34)28-15(2)14-27-23/h5-9,12-13,15,27H,1,10-11,14H2,2-4H3,(H,28,34)(H,29,33)(H,30,32)/t15-/m1/s1	ZJJPMWGHGIMGCI-OAHLLOKOSA-N	515431	US11098061, Compound III-35	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515431	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515431&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611125	461601539							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081959	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C25H22N4O2S/c1-4-21(30)29-19-11-15(6-5-13(19)2)17-8-7-16-18(28-17)9-10-20-22(16)23-24(32-20)25(31)27-14(3)12-26-23/h4-11,14,26H,1,12H2,2-3H3,(H,27,31)(H,29,30)/t14-/m1/s1	IMJPNXJHTNHNDW-CQSZACIVSA-N	515432	US11098061, Compound III-37	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515432&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611128	461601540							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081960	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C25H22N4O2S/c1-4-21(30)29-19-11-15(6-5-13(19)2)17-8-7-16-18(28-17)9-10-20-22(16)23-24(32-20)25(31)27-14(3)12-26-23/h4-11,14,26H,1,12H2,2-3H3,(H,27,31)(H,29,30)/t14-/m1/s1	IMJPNXJHTNHNDW-CQSZACIVSA-N	515432	US11098061, Compound III-37	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515432	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515432&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611128	461601540							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081961	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OCCN(C)C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C28H29N5O3S/c1-5-24(34)32-21-14-17(6-10-22(21)36-13-12-33(3)4)19-8-7-18-20(31-19)9-11-23-25(18)26-27(37-23)28(35)30-16(2)15-29-26/h5-11,14,16,29H,1,12-13,15H2,2-4H3,(H,30,35)(H,32,34)/t16-/m1/s1	IUTKLESKJIAAJU-MRXNPFEDSA-N	515433	US11098061, Compound III-40	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515433&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611113	461601541							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081962	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OCCN(C)C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C28H29N5O3S/c1-5-24(34)32-21-14-17(6-10-22(21)36-13-12-33(3)4)19-8-7-18-20(31-19)9-11-23-25(18)26-27(37-23)28(35)30-16(2)15-29-26/h5-11,14,16,29H,1,12-13,15H2,2-4H3,(H,30,35)(H,32,34)/t16-/m1/s1	IUTKLESKJIAAJU-MRXNPFEDSA-N	515433	US11098061, Compound III-40	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515433&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611113	461601541							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081963	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@H]2CCCN(C2)C(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)25-8-4-5-14(11-25)24-20(27)13-6-7-16-15(9-13)18-19(29-16)21(28)23-12(2)10-22-18/h3,6-7,9,12,14,22H,1,4-5,8,10-11H2,2H3,(H,23,28)(H,24,27)/t12-,14+/m1/s1	UJMSABPCQMBRGT-OCCSQVGLSA-N	515434	US11098061, Compound III-41	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515434&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611367	461601542							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081964	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@H]2CCCN(C2)S(=O)(=O)C=C)C(=O)N1	InChI=1S/C20H24N4O4S2/c1-3-30(27,28)24-8-4-5-14(11-24)23-19(25)13-6-7-16-15(9-13)17-18(29-16)20(26)22-12(2)10-21-17/h3,6-7,9,12,14,21H,1,4-5,8,10-11H2,2H3,(H,22,26)(H,23,25)/t12-,14+/m1/s1	SEBMSPKLVBVDQB-OCCSQVGLSA-N	515435	US11098061, Compound III-43	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515435&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611369	461601543							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081965	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OC(F)(F)F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C25H19F3N4O3S/c1-3-20(33)32-17-10-13(4-8-18(17)35-25(26,27)28)15-6-5-14-16(31-15)7-9-19-21(14)22-23(36-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	AWDDIFVUBWXECY-GFCCVEGCSA-N	515436	US11098061, Compound III-45	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515436&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611303	461601544							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081966	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OC(F)(F)F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C25H19F3N4O3S/c1-3-20(33)32-17-10-13(4-8-18(17)35-25(26,27)28)15-6-5-14-16(31-15)7-9-19-21(14)22-23(36-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	AWDDIFVUBWXECY-GFCCVEGCSA-N	515436	US11098061, Compound III-45	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515436&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611303	461601544							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081967	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(c(NC(=O)C=C)c2)C(F)(F)F)C(=O)N1	InChI=1S/C25H19F3N4O2S/c1-3-20(33)32-18-10-13(4-6-15(18)25(26,27)28)16-7-5-14-17(31-16)8-9-19-21(14)22-23(35-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	LEBXLGBPNIFTOL-GFCCVEGCSA-N	515437	US11098061, Compound III-46	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515437&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611197	461601545							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081968	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(c(NC(=O)C=C)c2)C(F)(F)F)C(=O)N1	InChI=1S/C25H19F3N4O2S/c1-3-20(33)32-18-10-13(4-6-15(18)25(26,27)28)16-7-5-14-17(31-16)8-9-19-21(14)22-23(35-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	LEBXLGBPNIFTOL-GFCCVEGCSA-N	515437	US11098061, Compound III-46	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515437&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611197	461601545							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081969	CCOc1ccc(Nc2c(C)c(NC3CCCNC3)nc3ccnn23)cc1NC(=O)C=C	InChI=1S/C23H29N7O2/c1-4-21(31)28-18-13-16(8-9-19(18)32-5-2)27-23-15(3)22(26-17-7-6-11-24-14-17)29-20-10-12-25-30(20)23/h4,8-10,12-13,17,24,27H,1,5-7,11,14H2,2-3H3,(H,26,29)(H,28,31)	STLFIEMORWZTRD-UHFFFAOYSA-N	515438	US11098061, Compound IV-1	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515438	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515438&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301349	461601546							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081970	CCOc1ccc(Nc2c(C)c(NC3CCCNC3)nc3ccnn23)c(NC(=O)C=C)c1	InChI=1S/C23H29N7O2/c1-4-21(31)27-19-13-17(32-5-2)8-9-18(19)28-23-15(3)22(26-16-7-6-11-24-14-16)29-20-10-12-25-30(20)23/h4,8-10,12-13,16,24,28H,1,5-7,11,14H2,2-3H3,(H,26,29)(H,27,31)	OARGAIXNYPDXML-UHFFFAOYSA-N	515439	US11098061, Compound IV-2	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515439&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90458061	461601547							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081971	CCOc1ccc(Nc2c(C)c(NC3CCCNC3)nc3ccnn23)c(NC(=O)C=C)c1	InChI=1S/C23H29N7O2/c1-4-21(31)27-19-13-17(32-5-2)8-9-18(19)28-23-15(3)22(26-16-7-6-11-24-14-16)29-20-10-12-25-30(20)23/h4,8-10,12-13,16,24,28H,1,5-7,11,14H2,2-3H3,(H,26,29)(H,27,31)	OARGAIXNYPDXML-UHFFFAOYSA-N	515439	US11098061, Compound IV-2	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515439	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515439&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90458061	461601547							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081972	Cc1c(NC2CCCNC2)nc2ccnn2c1NC(=O)C=C	InChI=1S/C15H20N6O/c1-3-13(22)20-15-10(2)14(18-11-5-4-7-16-9-11)19-12-6-8-17-21(12)15/h3,6,8,11,16H,1,4-5,7,9H2,2H3,(H,18,19)(H,20,22)	PGPASYJVLMYENH-UHFFFAOYSA-N	515440	US11098061, Compound IV-b-1	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515440	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515440&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301351	461601548							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081973	CCN1CCN(CC1)c1ccc(NC(=O)c2ccc3cc4C(=O)NCCn4c3c2)cc1NC(=O)C=C	InChI=1S/C27H30N6O3/c1-3-25(34)30-21-17-20(7-8-22(21)32-13-11-31(4-2)12-14-32)29-26(35)19-6-5-18-15-24-27(36)28-9-10-33(24)23(18)16-19/h3,5-8,15-17H,1,4,9-14H2,2H3,(H,28,36)(H,29,35)(H,30,34)	XUKHLHXVCUSOKA-UHFFFAOYSA-N	515441	US11098061, Compound V-1	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515441	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515441&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461524	461601549							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081974	C[C@@H]1CCN(C[C@@H]1NC(=O)C=C)C(=O)c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C21H24N4O3/c1-3-19(26)23-16-12-24(8-6-13(16)2)21(28)15-5-4-14-10-18-20(27)22-7-9-25(18)17(14)11-15/h3-5,10-11,13,16H,1,6-9,12H2,2H3,(H,22,27)(H,23,26)/t13-,16+/m1/s1	OXVYBWMNPDBCJM-CJNGLKHVSA-N	515442	US11098061, Compound V-2	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515442	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515442&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462047	461601550							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081975	C=CC(=O)N1CCC[C@H](C1)NC(=O)c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C20H22N4O3/c1-2-18(25)23-8-3-4-15(12-23)22-19(26)14-6-5-13-10-17-20(27)21-7-9-24(17)16(13)11-14/h2,5-6,10-11,15H,1,3-4,7-9,12H2,(H,21,27)(H,22,26)/t15-/m1/s1	HYOIPYRYERLLER-OAHLLOKOSA-N	515443	US11098061, Compound V-3	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515443	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515443&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461446	461601551							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081976	CN(C)C\C=C\C(=O)N1CCOc2ccc(NC(=O)c3ccc4cc5C(=O)NCCn5c4c3)cc12	InChI=1S/C26H27N5O4/c1-29(2)10-3-4-24(32)31-12-13-35-23-8-7-19(16-21(23)31)28-25(33)18-6-5-17-14-22-26(34)27-9-11-30(22)20(17)15-18/h3-8,14-16H,9-13H2,1-2H3,(H,27,34)(H,28,33)/b4-3+	JXZRWMHQJUHDPP-ONEGZZNKSA-N	515444	US11098061, Compound V-4	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515444	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515444&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611424	461601552							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081977	CN(C)C\C=C\C(=O)Nc1ccccc1NC(=O)c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C24H25N5O3/c1-28(2)12-5-8-22(30)26-18-6-3-4-7-19(18)27-23(31)17-10-9-16-14-21-24(32)25-11-13-29(21)20(16)15-17/h3-10,14-15H,11-13H2,1-2H3,(H,25,32)(H,26,30)(H,27,31)/b8-5+	NDEPLWPMHUAGTN-VMPITWQZSA-N	515445	US11098061, Compound V-5	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515445	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515445&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611306	461601553							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081978	C=CC(=O)N1CCOc2ccc(NC(=O)c3ccc4cc5C(=O)NCCn5c4c3)cc12	InChI=1S/C23H20N4O4/c1-2-21(28)27-9-10-31-20-6-5-16(13-18(20)27)25-22(29)15-4-3-14-11-19-23(30)24-7-8-26(19)17(14)12-15/h2-6,11-13H,1,7-10H2,(H,24,30)(H,25,29)	ZVOLXBONVQFWME-UHFFFAOYSA-N	515446	US11098061, Compound V-6	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515446&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462164	461601554							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081979	C=CC(=O)N1CCOc2ccc(NC(=O)c3ccc4cc5C(=O)NCCn5c4c3)cc12	InChI=1S/C23H20N4O4/c1-2-21(28)27-9-10-31-20-6-5-16(13-18(20)27)25-22(29)15-4-3-14-11-19-23(30)24-7-8-26(19)17(14)12-15/h2-6,11-13H,1,7-10H2,(H,24,30)(H,25,29)	ZVOLXBONVQFWME-UHFFFAOYSA-N	515446	US11098061, Compound V-6	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515446	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515446&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462164	461601554							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081980	C=CC(=O)Nc1cccc(NC(=O)c2ccc3cc4C(=O)NCCn4c3c2)c1	InChI=1S/C21H18N4O3/c1-2-19(26)23-15-4-3-5-16(12-15)24-20(27)14-7-6-13-10-18-21(28)22-8-9-25(18)17(13)11-14/h2-7,10-12H,1,8-9H2,(H,22,28)(H,23,26)(H,24,27)	AFRLNXWOUMBMJZ-UHFFFAOYSA-N	515447	US11098061, Compound V-7	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515447	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515447&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90460724	461601555							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081981	C=CC(=O)Nc1ccccc1NC(=O)c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C21H18N4O3/c1-2-19(26)23-15-5-3-4-6-16(15)24-20(27)14-8-7-13-11-18-21(28)22-9-10-25(18)17(13)12-14/h2-8,11-12H,1,9-10H2,(H,22,28)(H,23,26)(H,24,27)	YJZIUNQMHGXQKW-UHFFFAOYSA-N	515448	US11098061, Compound V-8	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515448	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515448&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461807	461601556							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081982	C=CC(=O)N1CCc2ccc(NC(=O)c3ccc4cc5C(=O)NCCn5c4c3)cc12	InChI=1S/C23H20N4O3/c1-2-21(28)27-9-7-14-5-6-17(13-19(14)27)25-22(29)16-4-3-15-11-20-23(30)24-8-10-26(20)18(15)12-16/h2-6,11-13H,1,7-10H2,(H,24,30)(H,25,29)	SIHUIDOVJQOLNV-UHFFFAOYSA-N	515449	US11098061, Compound V-9	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515449	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515449&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461751	461601557							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081983	C=CC(=O)NC1CCCCC1NC(=O)c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C21H24N4O3/c1-2-19(26)23-15-5-3-4-6-16(15)24-20(27)14-8-7-13-11-18-21(28)22-9-10-25(18)17(13)12-14/h2,7-8,11-12,15-16H,1,3-6,9-10H2,(H,22,28)(H,23,26)(H,24,27)	JWWBYMBMTLRQNM-UHFFFAOYSA-N	515450	US11098061, Compound V-10	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515450	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515450&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611259	461601558							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081984	C[O](C)c1ccc(cc1NC(=O)C=C)-c1cc(ccn1)-c1cc2C(=O)NCCn2c1	InChI=1S/C23H23N4O3/c1-4-22(28)26-19-12-16(5-6-21(19)30(2)3)18-11-15(7-8-24-18)17-13-20-23(29)25-9-10-27(20)14-17/h4-8,11-14H,1,9-10H2,2-3H3,(H,25,29)(H,26,28)	KVVIMOQLSSVETN-UHFFFAOYSA-N	515451	US11098061, Compound V-c-1	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515451	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515451&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461375	461601559							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081985	COc1ccc(cc1NC(=O)C=C)-c1nccc(n1)-c1cc2C(=O)NCCn2c1	InChI=1S/C21H19N5O3/c1-3-19(27)24-16-10-13(4-5-18(16)29-2)20-22-7-6-15(25-20)14-11-17-21(28)23-8-9-26(17)12-14/h3-7,10-12H,1,8-9H2,2H3,(H,23,28)(H,24,27)	UYAQOVWAAGPMCE-UHFFFAOYSA-N	515452	US11098061, Compound V-c-2	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515452&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461414	461601560							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081986	COc1ccc(cc1NC(=O)C=C)-c1nccc(n1)-c1cc2C(=O)NCCn2c1	InChI=1S/C21H19N5O3/c1-3-19(27)24-16-10-13(4-5-18(16)29-2)20-22-7-6-15(25-20)14-11-17-21(28)23-8-9-26(17)12-14/h3-7,10-12H,1,8-9H2,2H3,(H,23,28)(H,24,27)	UYAQOVWAAGPMCE-UHFFFAOYSA-N	515452	US11098061, Compound V-c-2	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515452	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515452&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461414	461601560							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081987	C=CC(=O)N1CCOc2ccc(cc12)-c1nccc(n1)-c1cc2C(=O)NCCn2c1	InChI=1S/C22H19N5O3/c1-2-20(28)27-9-10-30-19-4-3-14(11-17(19)27)21-23-6-5-16(25-21)15-12-18-22(29)24-7-8-26(18)13-15/h2-6,11-13H,1,7-10H2,(H,24,29)	ADQUCUIYTYKRFQ-UHFFFAOYSA-N	515453	US11098061, Compound V-c-3	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515453&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611255	461601561							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081988	C=CC(=O)N1CCOc2ccc(cc12)-c1nccc(n1)-c1cc2C(=O)NCCn2c1	InChI=1S/C22H19N5O3/c1-2-20(28)27-9-10-30-19-4-3-14(11-17(19)27)21-23-6-5-16(25-21)15-12-18-22(29)24-7-8-26(18)13-15/h2-6,11-13H,1,7-10H2,(H,24,29)	ADQUCUIYTYKRFQ-UHFFFAOYSA-N	515453	US11098061, Compound V-c-3	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515453	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515453&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611255	461601561							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081989	CN1CCN(CC1)c1ccc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)cc1NC(=O)C=C	InChI=1S/C29H32N6O3/c1-3-26(36)32-22-17-21(7-8-23(22)34-13-11-33(2)12-14-34)31-27(37)20-6-5-19-15-25-28(38)30-18-29(9-4-10-29)35(25)24(19)16-20/h3,5-8,15-17H,1,4,9-14,18H2,2H3,(H,30,38)(H,31,37)(H,32,36)	JSJNBFCXEUCJHR-UHFFFAOYSA-N	515454	US11098061, Compound V-15	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515454&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611140	461601562							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081990	CN1CCN(CC1)c1ccc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)cc1NC(=O)C=C	InChI=1S/C29H32N6O3/c1-3-26(36)32-22-17-21(7-8-23(22)34-13-11-33(2)12-14-34)31-27(37)20-6-5-19-15-25-28(38)30-18-29(9-4-10-29)35(25)24(19)16-20/h3,5-8,15-17H,1,4,9-14,18H2,2H3,(H,30,38)(H,31,37)(H,32,36)	JSJNBFCXEUCJHR-UHFFFAOYSA-N	515454	US11098061, Compound V-15	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515454	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515454&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611140	461601562							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081991	COc1ccc(cc1NC(=O)C=C)-c1cc(Nc2c(N[C@H](C)c3ccccc3)c(=O)c2=O)ccn1	InChI=1S/C27H24N4O4/c1-4-23(32)31-21-14-18(10-11-22(21)35-3)20-15-19(12-13-28-20)30-25-24(26(33)27(25)34)29-16(2)17-8-6-5-7-9-17/h4-16,29H,1H2,2-3H3,(H,28,30)(H,31,32)/t16-/m1/s1	GZUMLEXQZXYNGU-MRXNPFEDSA-N	515455	US11098061, Compound VI-9	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515455	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515455&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			162678173	461601563							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081992	C=CC(=O)Nc1cc(ccc1OCCCNC(=O)CCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@@H]12)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1			515456	US11098061, Compound Probe 1	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515456&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611426	461601564							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081993	C=CC(=O)Nc1cc(ccc1OCCCNC(=O)CCCC(=O)NCCCOCCOCCOCCCNC(=O)CCCC[C@H]1SC[C@H]2NC(=O)N[C@@H]12)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1			515456	US11098061, Compound Probe 1	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515456	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515456&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611426	461601564							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081994	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C28H27N5O2/c1-3-26(35)30-23-14-17(5-8-24(23)33-12-10-32(2)11-13-33)22-15-20-18(16-29-22)4-6-19-27-21(31-28(19)20)7-9-25(27)34/h3-6,8,14-16,31H,1,7,9-13H2,2H3,(H,30,35)	DPVLYBHPRDWKEE-UHFFFAOYSA-N	515457	N-(2-(4-methylpiperazin-1-yl)-5-(7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-4	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515457&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300756	461601565							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081995	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C28H27N5O2/c1-3-26(35)30-23-14-17(5-8-24(23)33-12-10-32(2)11-13-33)22-15-20-18(16-29-22)4-6-19-27-21(31-28(19)20)7-9-25(27)34/h3-6,8,14-16,31H,1,7,9-13H2,2H3,(H,30,35)	DPVLYBHPRDWKEE-UHFFFAOYSA-N	515457	N-(2-(4-methylpiperazin-1-yl)-5-(7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-4	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515457&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300756	461601565							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081996	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2c3n(C)c4CCC(=O)c4c3ccc2cn1	InChI=1S/C29H29N5O2/c1-4-27(36)31-23-15-18(6-8-24(23)34-13-11-32(2)12-14-34)22-16-21-19(17-30-22)5-7-20-28-25(9-10-26(28)35)33(3)29(20)21/h4-8,15-17H,1,9-14H2,2-3H3,(H,31,36)	ZIQOZCCHCHZPGU-UHFFFAOYSA-N	515458	US11098061, Compound II-e-15	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515458&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611137	461601566							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081997	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2c3n(C)c4CCC(=O)c4c3ccc2cn1	InChI=1S/C29H29N5O2/c1-4-27(36)31-23-15-18(6-8-24(23)34-13-11-32(2)12-14-34)22-16-21-19(17-30-22)5-7-20-28-25(9-10-26(28)35)33(3)29(20)21/h4-8,15-17H,1,9-14H2,2-3H3,(H,31,36)	ZIQOZCCHCHZPGU-UHFFFAOYSA-N	515458	US11098061, Compound II-e-15	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515458&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611137	461601566							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081998	C=CC(=O)N1CCOc2ccc(cc12)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C25H19N3O3/c1-2-23(30)28-9-10-31-22-8-4-14(11-20(22)28)19-12-17-15(13-26-19)3-5-16-24-18(27-25(16)17)6-7-21(24)29/h2-5,8,11-13,27H,1,6-7,9-10H2	AOWRXQNOWCVWSP-UHFFFAOYSA-N	515459	2-(4-acryloyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-8,9-dihydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-7(10H)-one::US11098061, Compound II-e-8	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515459&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300894	461601567							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081999	C=CC(=O)N1CCOc2ccc(cc12)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C25H19N3O3/c1-2-23(30)28-9-10-31-22-8-4-14(11-20(22)28)19-12-17-15(13-26-19)3-5-16-24-18(27-25(16)17)6-7-21(24)29/h2-5,8,11-13,27H,1,6-7,9-10H2	AOWRXQNOWCVWSP-UHFFFAOYSA-N	515459	2-(4-acryloyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-8,9-dihydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-7(10H)-one::US11098061, Compound II-e-8	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515459	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515459&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300894	461601567							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082000	CC1CN(C(=O)C=C)c2cc(ccc2O1)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1			515460	2-(4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-8,9-dihydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-7(10H)-one::US11098061, Compound II-e-17	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515460&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611141	461601568							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082001	CC1CN(C(=O)C=C)c2cc(ccc2O1)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1			515460	2-(4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-8,9-dihydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-7(10H)-one::US11098061, Compound II-e-17	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515460	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515460&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611141	461601568							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082002	Cc1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C24H19N3O2/c1-3-22(29)26-19-10-14(5-4-13(19)2)20-11-17-15(12-25-20)6-7-16-23-18(27-24(16)17)8-9-21(23)28/h3-7,10-12,27H,1,8-9H2,2H3,(H,26,29)	GOWZNLUJQQDUEB-UHFFFAOYSA-N	515461	N-(2-methyl-5-(7-oxo-7,8,9, 1-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-19	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515461&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611100	461601569							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082003	Cc1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C24H19N3O2/c1-3-22(29)26-19-10-14(5-4-13(19)2)20-11-17-15(12-25-20)6-7-16-23-18(27-24(16)17)8-9-21(23)28/h3-7,10-12,27H,1,8-9H2,2H3,(H,26,29)	GOWZNLUJQQDUEB-UHFFFAOYSA-N	515461	N-(2-methyl-5-(7-oxo-7,8,9, 1-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-19	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515461	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515461&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611100	461601569							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082004	Clc1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C23H16ClN3O2/c1-2-21(29)26-19-9-12(4-6-16(19)24)18-10-15-13(11-25-18)3-5-14-22-17(27-23(14)15)7-8-20(22)28/h2-6,9-11,27H,1,7-8H2,(H,26,29)	WGYGBMQMNZBDRT-UHFFFAOYSA-N	515462	N-(2-chloro-5-(7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-20	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515462&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611101	461601570							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082005	Clc1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C23H16ClN3O2/c1-2-21(29)26-19-9-12(4-6-16(19)24)18-10-15-13(11-25-18)3-5-14-22-17(27-23(14)15)7-8-20(22)28/h2-6,9-11,27H,1,7-8H2,(H,26,29)	WGYGBMQMNZBDRT-UHFFFAOYSA-N	515462	N-(2-chloro-5-(7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-20	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515462	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515462&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611101	461601570							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082006	COc1ncc(cc1NC(=O)C=C)-c1cc2c3n(C)c4CCC(=O)c4c3ccc2cn1	InChI=1S/C24H20N4O3/c1-4-21(30)27-18-9-14(12-26-24(18)31-3)17-10-16-13(11-25-17)5-6-15-22-19(7-8-20(22)29)28(2)23(15)16/h4-6,9-12H,1,7-8H2,2-3H3,(H,27,30)	FEWAFKJGDZPORE-UHFFFAOYSA-N	515463	N-(2-methoxy-5-(10-methyl-7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)pyridin-3-yl)acrylamide::US11098061, Compound II-e-21	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515463&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611201	461601571							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082007	COc1ncc(cc1NC(=O)C=C)-c1cc2c3n(C)c4CCC(=O)c4c3ccc2cn1	InChI=1S/C24H20N4O3/c1-4-21(30)27-18-9-14(12-26-24(18)31-3)17-10-16-13(11-25-17)5-6-15-22-19(7-8-20(22)29)28(2)23(15)16/h4-6,9-12H,1,7-8H2,2-3H3,(H,27,30)	FEWAFKJGDZPORE-UHFFFAOYSA-N	515463	N-(2-methoxy-5-(10-methyl-7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)pyridin-3-yl)acrylamide::US11098061, Compound II-e-21	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515463&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611201	461601571							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082008	Cc1cc(NC(=O)C=C)cc(c1)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C24H19N3O2/c1-3-22(29)26-16-9-13(2)8-15(10-16)20-11-18-14(12-25-20)4-5-17-23-19(27-24(17)18)6-7-21(23)28/h3-5,8-12,27H,1,6-7H2,2H3,(H,26,29)	TUNCAJPNGQHWKR-UHFFFAOYSA-N	515464	N-(3-methyl-5-(7-oxo-7,8,9, 1-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-22	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515464	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515464&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611220	461601572							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082009	Cc1cc(NC(=O)C=C)cc(c1)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C24H19N3O2/c1-3-22(29)26-16-9-13(2)8-15(10-16)20-11-18-14(12-25-20)4-5-17-23-19(27-24(17)18)6-7-21(23)28/h3-5,8-12,27H,1,6-7H2,2H3,(H,26,29)	TUNCAJPNGQHWKR-UHFFFAOYSA-N	515464	N-(3-methyl-5-(7-oxo-7,8,9, 1-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-22	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515464	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515464&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611220	461601572							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082010	CC(=O)N1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C29H27N5O3/c1-3-27(37)31-24-14-18(5-8-25(24)34-12-10-33(11-13-34)17(2)35)23-15-21-19(16-30-23)4-6-20-28-22(32-29(20)21)7-9-26(28)36/h3-6,8,14-16,32H,1,7,9-13H2,2H3,(H,31,37)	LFTVJZZIVOUEJG-UHFFFAOYSA-N	515465	N-(2-(4-acetylpiperazin-1-yl)-5-(7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-23	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515465&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462288	461601573							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082011	CC(=O)N1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C29H27N5O3/c1-3-27(37)31-24-14-18(5-8-25(24)34-12-10-33(11-13-34)17(2)35)23-15-21-19(16-30-23)4-6-20-28-22(32-29(20)21)7-9-26(28)36/h3-6,8,14-16,32H,1,7,9-13H2,2H3,(H,31,37)	LFTVJZZIVOUEJG-UHFFFAOYSA-N	515465	N-(2-(4-acetylpiperazin-1-yl)-5-(7-oxo-7,8,9,10-tetrahydrocyclopenta[4,5]pyrrolo[2,3-f]isoquinolin-2-yl)phenyl)acrylamide::US11098061, Compound II-e-23	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515465	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515465&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462288	461601573							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082012	C[C@@H]1CN(C(=O)C=C)c2cc(NC(=O)c3ccc4sc5c(NC[C@@H](C)NC5=O)c4c3)ccc2O1	InChI=1S/C25H24N4O4S/c1-4-21(30)29-12-14(3)33-19-7-6-16(10-18(19)29)28-24(31)15-5-8-20-17(9-15)22-23(34-20)25(32)27-13(2)11-26-22/h4-10,13-14,26H,1,11-12H2,2-3H3,(H,27,32)(H,28,31)/t13-,14-/m1/s1	VKRNAJLNPBXBDD-ZIAGYGMSSA-N	515466	(R)&#151;N&#151;((R)-4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide (III-31) and (R)&#151;N&#151;((S)-4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide (III-53)::US11098061, Compound III-31	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515466&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462122	461601574							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082013	C[C@@H]1CN(C(=O)C=C)c2cc(NC(=O)c3ccc4sc5c(NC[C@@H](C)NC5=O)c4c3)ccc2O1	InChI=1S/C25H24N4O4S/c1-4-21(30)29-12-14(3)33-19-7-6-16(10-18(19)29)28-24(31)15-5-8-20-17(9-15)22-23(34-20)25(32)27-13(2)11-26-22/h4-10,13-14,26H,1,11-12H2,2-3H3,(H,27,32)(H,28,31)/t13-,14-/m1/s1	VKRNAJLNPBXBDD-ZIAGYGMSSA-N	515466	(R)&#151;N&#151;((R)-4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide (III-31) and (R)&#151;N&#151;((S)-4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide (III-53)::US11098061, Compound III-31	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515466	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515466&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462122	461601574							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082014	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc3OC(C)(C)CN(C(=O)C=C)c3c2)C(=O)N1	InChI=1S/C26H26N4O4S/c1-5-21(31)30-13-26(3,4)34-19-8-7-16(11-18(19)30)29-24(32)15-6-9-20-17(10-15)22-23(35-20)25(33)28-14(2)12-27-22/h5-11,14,27H,1,12-13H2,2-4H3,(H,28,33)(H,29,32)/t14-/m1/s1	IOCMHHFAUKVGPR-CQSZACIVSA-N	515467	(R)&#151;N-(4-acryloyl-2,2-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide::US11098061, Compound III-32	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515467&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90460941	461601575							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082015	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc3OC(C)(C)CN(C(=O)C=C)c3c2)C(=O)N1	InChI=1S/C26H26N4O4S/c1-5-21(31)30-13-26(3,4)34-19-8-7-16(11-18(19)30)29-24(32)15-6-9-20-17(10-15)22-23(35-20)25(33)28-14(2)12-27-22/h5-11,14,27H,1,12-13H2,2-4H3,(H,28,33)(H,29,32)/t14-/m1/s1	IOCMHHFAUKVGPR-CQSZACIVSA-N	515467	(R)&#151;N-(4-acryloyl-2,2-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide::US11098061, Compound III-32	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515467	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515467&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90460941	461601575							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082016	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OCCN(C)C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C28H29N5O3S/c1-5-24(34)32-21-14-17(6-10-22(21)36-13-12-33(3)4)19-8-7-18-20(31-19)9-11-23-25(18)26-27(37-23)28(35)30-16(2)15-29-26/h5-11,14,16,29H,1,12-13,15H2,2-4H3,(H,30,35)(H,32,34)/t16-/m1/s1	IUTKLESKJIAAJU-MRXNPFEDSA-N	515433	US11098061, Compound III-40	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515433&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611113	461601541							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082017	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OCCN(C)C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C28H29N5O3S/c1-5-24(34)32-21-14-17(6-10-22(21)36-13-12-33(3)4)19-8-7-18-20(31-19)9-11-23-25(18)26-27(37-23)28(35)30-16(2)15-29-26/h5-11,14,16,29H,1,12-13,15H2,2-4H3,(H,30,35)(H,32,34)/t16-/m1/s1	IUTKLESKJIAAJU-MRXNPFEDSA-N	515433	US11098061, Compound III-40	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515433	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515433&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611113	461601541							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082018	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@H]2CCCN(C2)C(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)25-8-4-5-14(11-25)24-20(27)13-6-7-16-15(9-13)18-19(29-16)21(28)23-12(2)10-22-18/h3,6-7,9,12,14,22H,1,4-5,8,10-11H2,2H3,(H,23,28)(H,24,27)/t12-,14+/m1/s1	UJMSABPCQMBRGT-OCCSQVGLSA-N	515434	US11098061, Compound III-41	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515434&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611367	461601542							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082019	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@H]2CCCN(C2)C(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)25-8-4-5-14(11-25)24-20(27)13-6-7-16-15(9-13)18-19(29-16)21(28)23-12(2)10-22-18/h3,6-7,9,12,14,22H,1,4-5,8,10-11H2,2H3,(H,23,28)(H,24,27)/t12-,14+/m1/s1	UJMSABPCQMBRGT-OCCSQVGLSA-N	515434	US11098061, Compound III-41	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515434	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515434&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611367	461601542							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082020	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@@H]2CCCN(C2)C(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)25-8-4-5-14(11-25)24-20(27)13-6-7-16-15(9-13)18-19(29-16)21(28)23-12(2)10-22-18/h3,6-7,9,12,14,22H,1,4-5,8,10-11H2,2H3,(H,23,28)(H,24,27)/t12-,14-/m1/s1	UJMSABPCQMBRGT-TZMCWYRMSA-N	515468	US11098061, Compound III-42	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515468&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118603757	461601576							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082021	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@@H]2CCCN(C2)C(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)25-8-4-5-14(11-25)24-20(27)13-6-7-16-15(9-13)18-19(29-16)21(28)23-12(2)10-22-18/h3,6-7,9,12,14,22H,1,4-5,8,10-11H2,2H3,(H,23,28)(H,24,27)/t12-,14-/m1/s1	UJMSABPCQMBRGT-TZMCWYRMSA-N	515468	US11098061, Compound III-42	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515468	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515468&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118603757	461601576							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082022	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@H]2CCCN(C2)S(=O)(=O)C=C)C(=O)N1	InChI=1S/C20H24N4O4S2/c1-3-30(27,28)24-8-4-5-14(11-24)23-19(25)13-6-7-16-15(9-13)17-18(29-16)20(26)22-12(2)10-21-17/h3,6-7,9,12,14,21H,1,4-5,8,10-11H2,2H3,(H,22,26)(H,23,25)/t12-,14+/m1/s1	SEBMSPKLVBVDQB-OCCSQVGLSA-N	515435	US11098061, Compound III-43	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515435&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611369	461601543							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082023	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@H]2CCCN(C2)S(=O)(=O)C=C)C(=O)N1	InChI=1S/C20H24N4O4S2/c1-3-30(27,28)24-8-4-5-14(11-24)23-19(25)13-6-7-16-15(9-13)17-18(29-16)20(26)22-12(2)10-21-17/h3,6-7,9,12,14,21H,1,4-5,8,10-11H2,2H3,(H,22,26)(H,23,25)/t12-,14+/m1/s1	SEBMSPKLVBVDQB-OCCSQVGLSA-N	515435	US11098061, Compound III-43	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515435	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515435&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611369	461601543							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082024	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@@H]2CCCN(C2)S(=O)(=O)C=C)C(=O)N1	InChI=1S/C20H24N4O4S2/c1-3-30(27,28)24-8-4-5-14(11-24)23-19(25)13-6-7-16-15(9-13)17-18(29-16)20(26)22-12(2)10-21-17/h3,6-7,9,12,14,21H,1,4-5,8,10-11H2,2H3,(H,22,26)(H,23,25)/t12-,14-/m1/s1	SEBMSPKLVBVDQB-TZMCWYRMSA-N	515469	US11098061, Compound III-44	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515469&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611349	461601577							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082025	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)N[C@@H]2CCCN(C2)S(=O)(=O)C=C)C(=O)N1	InChI=1S/C20H24N4O4S2/c1-3-30(27,28)24-8-4-5-14(11-24)23-19(25)13-6-7-16-15(9-13)17-18(29-16)20(26)22-12(2)10-21-17/h3,6-7,9,12,14,21H,1,4-5,8,10-11H2,2H3,(H,22,26)(H,23,25)/t12-,14-/m1/s1	SEBMSPKLVBVDQB-TZMCWYRMSA-N	515469	US11098061, Compound III-44	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515469	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515469&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611349	461601577							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082026	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OC(F)(F)F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C25H19F3N4O3S/c1-3-20(33)32-17-10-13(4-8-18(17)35-25(26,27)28)15-6-5-14-16(31-15)7-9-19-21(14)22-23(36-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	AWDDIFVUBWXECY-GFCCVEGCSA-N	515436	US11098061, Compound III-45	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515436&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611303	461601544							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082027	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(OC(F)(F)F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C25H19F3N4O3S/c1-3-20(33)32-17-10-13(4-8-18(17)35-25(26,27)28)15-6-5-14-16(31-15)7-9-19-21(14)22-23(36-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	AWDDIFVUBWXECY-GFCCVEGCSA-N	515436	US11098061, Compound III-45	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515436	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515436&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611303	461601544							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082028	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(c(NC(=O)C=C)c2)C(F)(F)F)C(=O)N1	InChI=1S/C25H19F3N4O2S/c1-3-20(33)32-18-10-13(4-6-15(18)25(26,27)28)16-7-5-14-17(31-16)8-9-19-21(14)22-23(35-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	LEBXLGBPNIFTOL-GFCCVEGCSA-N	515437	US11098061, Compound III-46	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515437&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611197	461601545							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082029	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(c(NC(=O)C=C)c2)C(F)(F)F)C(=O)N1	InChI=1S/C25H19F3N4O2S/c1-3-20(33)32-18-10-13(4-6-15(18)25(26,27)28)16-7-5-14-17(31-16)8-9-19-21(14)22-23(35-19)24(34)30-12(2)11-29-22/h3-10,12,29H,1,11H2,2H3,(H,30,34)(H,32,33)/t12-/m1/s1	LEBXLGBPNIFTOL-GFCCVEGCSA-N	515437	US11098061, Compound III-46	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515437	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515437&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611197	461601545							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082030	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)NC2CCCC2NC(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)24-14-5-4-6-15(14)25-20(27)12-7-8-16-13(9-12)18-19(29-16)21(28)23-11(2)10-22-18/h3,7-9,11,14-15,22H,1,4-6,10H2,2H3,(H,23,28)(H,24,26)(H,25,27)/t11-,14?,15?/m1/s1	IWRRIDADTCIEEA-VCANKDNSSA-N	515470	US11098061, Compound III-47	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515470&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611371	461601578							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082031	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)NC2CCCC2NC(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)24-14-5-4-6-15(14)25-20(27)12-7-8-16-13(9-12)18-19(29-16)21(28)23-11(2)10-22-18/h3,7-9,11,14-15,22H,1,4-6,10H2,2H3,(H,23,28)(H,24,26)(H,25,27)/t11-,14?,15?/m1/s1	IWRRIDADTCIEEA-VCANKDNSSA-N	515470	US11098061, Compound III-47	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515470	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515470&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611371	461601578							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082032	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)NC2COCC2NC(=O)C=C)C(=O)N1	InChI=1S/C20H22N4O4S/c1-3-16(25)23-13-8-28-9-14(13)24-19(26)11-4-5-15-12(6-11)17-18(29-15)20(27)22-10(2)7-21-17/h3-6,10,13-14,21H,1,7-9H2,2H3,(H,22,27)(H,23,25)(H,24,26)/t10-,13?,14?/m1/s1	PUMVZFFETWAVMF-GWMXKSKGSA-N	515471	US11098061, Compound III-48	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515471	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515471&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611370	461601579							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082033	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)NC2CS(=O)(=O)CC2NC(=O)C=C)C(=O)N1	InChI=1S/C20H22N4O5S2/c1-3-16(25)23-13-8-31(28,29)9-14(13)24-19(26)11-4-5-15-12(6-11)17-18(30-15)20(27)22-10(2)7-21-17/h3-6,10,13-14,21H,1,7-9H2,2H3,(H,22,27)(H,23,25)(H,24,26)/t10-,13?,14?/m1/s1	NZWAKUBTNQOVRG-GWMXKSKGSA-N	515472	US11098061, Compound III-49	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515472	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515472&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611372	461601580							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082034	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)NC2CN(C)CC2NC(=O)C=C)C(=O)N1	InChI=1S/C21H25N5O3S/c1-4-17(27)24-14-9-26(3)10-15(14)25-20(28)12-5-6-16-13(7-12)18-19(30-16)21(29)23-11(2)8-22-18/h4-7,11,14-15,22H,1,8-10H2,2-3H3,(H,23,29)(H,24,27)(H,25,28)/t11-,14?,15?/m1/s1	VHQMVIFMCCUEHA-VCANKDNSSA-N	515473	US11098061, Compound III-50	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515473	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515473&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611294	461601581							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082035	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)NC2CCCN(C2)C(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)25-8-4-5-14(11-25)24-20(27)13-6-7-16-15(9-13)18-19(29-16)21(28)23-12(2)10-22-18/h3,6-7,9,12,14,22H,1,4-5,8,10-11H2,2H3,(H,23,28)(H,24,27)/t12-,14?/m1/s1	UJMSABPCQMBRGT-PUODRLBUSA-N	515474	US11098061, Compound III-51	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515474&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461985	461601582							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082036	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)NC2CCCN(C2)C(=O)C=C)C(=O)N1	InChI=1S/C21H24N4O3S/c1-3-17(26)25-8-4-5-14(11-25)24-20(27)13-6-7-16-15(9-13)18-19(29-16)21(28)23-12(2)10-22-18/h3,6-7,9,12,14,22H,1,4-5,8,10-11H2,2H3,(H,23,28)(H,24,27)/t12-,14?/m1/s1	UJMSABPCQMBRGT-PUODRLBUSA-N	515474	US11098061, Compound III-51	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515474	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515474&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461985	461601582							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082037	C[C@H]1CN(C(=O)C=C)c2cc(NC(=O)c3ccc4sc5c(NC[C@@H](C)NC5=O)c4c3)ccc2O1	InChI=1S/C25H24N4O4S/c1-4-21(30)29-12-14(3)33-19-7-6-16(10-18(19)29)28-24(31)15-5-8-20-17(9-15)22-23(34-20)25(32)27-13(2)11-26-22/h4-10,13-14,26H,1,11-12H2,2-3H3,(H,27,32)(H,28,31)/t13-,14+/m1/s1	VKRNAJLNPBXBDD-KGLIPLIRSA-N	515475	US11098061, Compound III-53	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515475&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461278	461601583							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082038	C[C@H]1CN(C(=O)C=C)c2cc(NC(=O)c3ccc4sc5c(NC[C@@H](C)NC5=O)c4c3)ccc2O1	InChI=1S/C25H24N4O4S/c1-4-21(30)29-12-14(3)33-19-7-6-16(10-18(19)29)28-24(31)15-5-8-20-17(9-15)22-23(34-20)25(32)27-13(2)11-26-22/h4-10,13-14,26H,1,11-12H2,2-3H3,(H,27,32)(H,28,31)/t13-,14+/m1/s1	VKRNAJLNPBXBDD-KGLIPLIRSA-N	515475	US11098061, Compound III-53	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515475	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515475&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461278	461601583							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082039	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(Cl)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C24H19ClN4O2S/c1-3-20(30)29-18-10-13(4-6-15(18)25)16-7-5-14-17(28-16)8-9-19-21(14)22-23(32-19)24(31)27-12(2)11-26-22/h3-10,12,26H,1,11H2,2H3,(H,27,31)(H,29,30)/t12-/m1/s1	SGDHHQSIYZPVKG-GFCCVEGCSA-N	515476	(R)&#151;N-(2-chloro-5-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5&#8242;,6&#8242;:4,5]thieno[3,2-f]quinolin-3-yl)phenyl)acrylamide::US11098061, Compound III-54	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515476&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611224	461601584							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082040	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(Cl)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C24H19ClN4O2S/c1-3-20(30)29-18-10-13(4-6-15(18)25)16-7-5-14-17(28-16)8-9-19-21(14)22-23(32-19)24(31)27-12(2)11-26-22/h3-10,12,26H,1,11H2,2H3,(H,27,31)(H,29,30)/t12-/m1/s1	SGDHHQSIYZPVKG-GFCCVEGCSA-N	515476	(R)&#151;N-(2-chloro-5-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5&#8242;,6&#8242;:4,5]thieno[3,2-f]quinolin-3-yl)phenyl)acrylamide::US11098061, Compound III-54	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515476	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515476&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611224	461601584							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082041	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc3OC(C)(C)CN(C(=O)C=C)c3c2)C(=O)N1	InChI=1S/C28H26N4O3S/c1-5-23(33)32-14-28(3,4)35-21-10-6-16(12-20(21)32)18-8-7-17-19(31-18)9-11-22-24(17)25-26(36-22)27(34)30-15(2)13-29-25/h5-12,15,29H,1,13-14H2,2-4H3,(H,30,34)/t15-/m1/s1	JTXZQZQFMBATBB-OAHLLOKOSA-N	515477	(R)-3-(4-acryloyl-2,2-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5&#8242;,6&#8242;:4,5]thieno[3,2-f]quinolin-8-one::US11098061, Compound III-55	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515477	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515477&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611196	461601585							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082042	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(C3CCN(C)CC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C28H31N5O3S/c1-4-24(34)32-22-14-19(6-7-20(22)17-9-11-33(3)12-10-17)31-27(35)18-5-8-23-21(13-18)25-26(37-23)28(36)30-16(2)15-29-25/h4-8,13-14,16-17,29H,1,9-12,15H2,2-3H3,(H,30,36)(H,31,35)(H,32,34)/t16-/m1/s1	CYIKXRLTNTYHBH-MRXNPFEDSA-N	515478	(R)&#151;N-(3-acrylamido-4-(1-methylpiperidin-4-yl)phenyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide::US11098061, Compound III-56	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515478&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117610995	461601586							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082043	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(C3CCN(C)CC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C28H31N5O3S/c1-4-24(34)32-22-14-19(6-7-20(22)17-9-11-33(3)12-10-17)31-27(35)18-5-8-23-21(13-18)25-26(37-23)28(36)30-16(2)15-29-25/h4-8,13-14,16-17,29H,1,9-12,15H2,2-3H3,(H,30,36)(H,31,35)(H,32,34)/t16-/m1/s1	CYIKXRLTNTYHBH-MRXNPFEDSA-N	515478	(R)&#151;N-(3-acrylamido-4-(1-methylpiperidin-4-yl)phenyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide::US11098061, Compound III-56	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515478	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515478&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117610995	461601586							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082044	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(c(NC(=O)C=C)c2)C(F)(F)F)C(=O)N1	InChI=1S/C23H19F3N4O3S/c1-3-18(31)30-16-9-13(5-6-15(16)23(24,25)26)29-21(32)12-4-7-17-14(8-12)19-20(34-17)22(33)28-11(2)10-27-19/h3-9,11,27H,1,10H2,2H3,(H,28,33)(H,29,32)(H,30,31)/t11-/m1/s1	WVETWTDRLABSQB-LLVKDONJSA-N	515479	(R)&#151;N-(3-acrylamido-4-(trifluoromethyl)phenyl)-3-methyl-5-oxo-2,3,4,5-tetrahydro-1H-benzo[4,5]thieno[3,2-e][1,4]diazepine-9-carboxamide::US11098061, Compound III-57	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515479	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515479&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611297	461601587							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082045	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C3CCN(C)CC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C30H31N5O2S/c1-4-26(36)34-24-15-19(5-6-20(24)18-11-13-35(3)14-12-18)22-8-7-21-23(33-22)9-10-25-27(21)28-29(38-25)30(37)32-17(2)16-31-28/h4-10,15,17-18,31H,1,11-14,16H2,2-3H3,(H,32,37)(H,34,36)/t17-/m1/s1	QPRYQNHVWPQHFJ-QGZVFWFLSA-N	515480	(R)&#151;N-(5-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5&#8242;,6&#8242;:4,5]thieno[3,2-f]quinolin-3-yl)-2-(1-methylpiperidin-4-yl)phenyl)acrylamide::US11098061, Compound III-58	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611317	461601588							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082046	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C3CCN(C)CC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C30H31N5O2S/c1-4-26(36)34-24-15-19(5-6-20(24)18-11-13-35(3)14-12-18)22-8-7-21-23(33-22)9-10-25-27(21)28-29(38-25)30(37)32-17(2)16-31-28/h4-10,15,17-18,31H,1,11-14,16H2,2-3H3,(H,32,37)(H,34,36)/t17-/m1/s1	QPRYQNHVWPQHFJ-QGZVFWFLSA-N	515480	(R)&#151;N-(5-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5&#8242;,6&#8242;:4,5]thieno[3,2-f]quinolin-3-yl)-2-(1-methylpiperidin-4-yl)phenyl)acrylamide::US11098061, Compound III-58	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515480	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515480&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611317	461601588							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082047	Cc1ccc2oc(nc2c1NC(=O)C=C)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C25H22N4O3/c1-3-20(30)27-21-14(2)5-8-19-22(21)28-24(32-19)16-7-6-15-11-18-23(31)26-13-25(9-4-10-25)29(18)17(15)12-16/h3,5-8,11-12H,1,4,9-10,13H2,2H3,(H,26,31)(H,27,30)	IBSIOGTXBJVBJG-UHFFFAOYSA-N	515481	N-(5-methyl-2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-12	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515481&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611175	461601589							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082048	C=CC(=O)Nc1ccccc1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H22N4O3/c1-2-21(29)26-17-6-3-4-7-18(17)27-22(30)16-9-8-15-12-20-23(31)25-14-24(10-5-11-24)28(20)19(15)13-16/h2-4,6-9,12-13H,1,5,10-11,14H2,(H,25,31)(H,26,29)(H,27,30)	PAFHYDPUMKXVPI-UHFFFAOYSA-N	515482	N-(2-acrylamidophenyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-14	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515482	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515482&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611351	461601590							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082049	C=CC(=O)NCc1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1	InChI=1S/C22H21N5O3S/c1-2-18(28)23-10-15-11-31-21(25-15)26-19(29)14-5-4-13-8-17-20(30)24-12-22(6-3-7-22)27(17)16(13)9-14/h2,4-5,8-9,11H,1,3,6-7,10,12H2,(H,23,28)(H,24,30)(H,25,26,29)	HVOKUTOPCREAGZ-UHFFFAOYSA-N	515483	N-(4-(acrylamidomethyl)thiazol-2-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-43	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515483	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515483&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611160	461601591							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082050	C=CC(=O)N1CCc2ccc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)cc12	InChI=1S/C26H24N4O3/c1-2-23(31)29-11-8-16-6-7-19(14-20(16)29)28-24(32)18-5-4-17-12-22-25(33)27-15-26(9-3-10-26)30(22)21(17)13-18/h2,4-7,12-14H,1,3,8-11,15H2,(H,27,33)(H,28,32)	UYHSMQWLRKSEAR-UHFFFAOYSA-N	515484	N-(1-acryloylindolin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-45	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515484&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611007	461601592							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082051	C=CC(=O)N1CCc2ccc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)cc12	InChI=1S/C26H24N4O3/c1-2-23(31)29-11-8-16-6-7-19(14-20(16)29)28-24(32)18-5-4-17-12-22-25(33)27-15-26(9-3-10-26)30(22)21(17)13-18/h2,4-7,12-14H,1,3,8-11,15H2,(H,27,33)(H,28,32)	UYHSMQWLRKSEAR-UHFFFAOYSA-N	515484	N-(1-acryloylindolin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-45	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515484	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515484&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611007	461601592							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082052	C=CC(=O)NC1CCCCC1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H28N4O3/c1-2-21(29)26-17-6-3-4-7-18(17)27-22(30)16-9-8-15-12-20-23(31)25-14-24(10-5-11-24)28(20)19(15)13-16/h2,8-9,12-13,17-18H,1,3-7,10-11,14H2,(H,25,31)(H,26,29)(H,27,30)	LWVJZQMVANOTLN-UHFFFAOYSA-N	515485	BDBM515503::Cis-N-(2-acrylamidocyclohexyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-46	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515485&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611165	461601593							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082053	C=CC(=O)N1CCC[C@@H](C1)NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C23H26N4O3/c1-2-20(28)26-10-3-5-17(13-26)25-21(29)16-7-6-15-11-19-22(30)24-14-23(8-4-9-23)27(19)18(15)12-16/h2,6-7,11-12,17H,1,3-5,8-10,13-14H2,(H,24,30)(H,25,29)/t17-/m0/s1	SYQUXCLULQBMET-KRWDZBQOSA-N	515486	(S)&#151;N-(1-acryloylpiperidin-3-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-47	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515486	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515486&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611226	461601594							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082054	C=CC(=O)N1Cc2cccc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)c2C1	InChI=1S/C26H24N4O3/c1-2-23(31)29-13-18-5-3-6-20(19(18)14-29)28-24(32)17-8-7-16-11-22-25(33)27-15-26(9-4-10-26)30(22)21(16)12-17/h2-3,5-8,11-12H,1,4,9-10,13-15H2,(H,27,33)(H,28,32)	SWSSMHZOCNCBTC-UHFFFAOYSA-N	515487	N-(2-acryloylisoindolin-4-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-48	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515487	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515487&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611266	461601595							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082055	C=CC(=O)NC1COCC1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C22H24N4O4/c1-2-19(27)24-15-10-30-11-16(15)25-20(28)14-5-4-13-8-18-21(29)23-12-22(6-3-7-22)26(18)17(13)9-14/h2,4-5,8-9,15-16H,1,3,6-7,10-12H2,(H,23,29)(H,24,27)(H,25,28)	MSNTVQMFTZWEPW-UHFFFAOYSA-N	515488	Cis-N-(4-acrylamidotetrahydrofuran-3-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-49	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515488	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515488&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611205	461601596							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082056	CC1CN(C(=O)C=C)c2cc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)ccc2O1	InChI=1S/C27H26N4O4/c1-3-24(32)30-14-16(2)35-23-8-7-19(13-21(23)30)29-25(33)18-6-5-17-11-22-26(34)28-15-27(9-4-10-27)31(22)20(17)12-18/h3,5-8,11-13,16H,1,4,9-10,14-15H2,2H3,(H,28,34)(H,29,33)	MKJVXPXIANXMAX-UHFFFAOYSA-N	515489	N-(4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-50	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515489&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611379	461601597							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082057	CC1CN(C(=O)C=C)c2cc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)ccc2O1	InChI=1S/C27H26N4O4/c1-3-24(32)30-14-16(2)35-23-8-7-19(13-21(23)30)29-25(33)18-6-5-17-11-22-26(34)28-15-27(9-4-10-27)31(22)20(17)12-18/h3,5-8,11-13,16H,1,4,9-10,14-15H2,2H3,(H,28,34)(H,29,33)	MKJVXPXIANXMAX-UHFFFAOYSA-N	515489	N-(4-acryloyl-2-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-50	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515489	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515489&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611379	461601597							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082058	CC1(C)CN(C(=O)C=C)c2cc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)ccc2O1	InChI=1S/C28H28N4O4/c1-4-24(33)31-16-27(2,3)36-23-9-8-19(14-21(23)31)30-25(34)18-7-6-17-12-22-26(35)29-15-28(10-5-11-28)32(22)20(17)13-18/h4,6-9,12-14H,1,5,10-11,15-16H2,2-3H3,(H,29,35)(H,30,34)	XITQTZHPIQKPEO-UHFFFAOYSA-N	515490	N-(4-acryloyl-2,2-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-51	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515490&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611363	461601598							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082059	CC1(C)CN(C(=O)C=C)c2cc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)ccc2O1	InChI=1S/C28H28N4O4/c1-4-24(33)31-16-27(2,3)36-23-9-8-19(14-21(23)31)30-25(34)18-7-6-17-12-22-26(35)29-15-28(10-5-11-28)32(22)20(17)13-18/h4,6-9,12-14H,1,5,10-11,15-16H2,2-3H3,(H,29,35)(H,30,34)	XITQTZHPIQKPEO-UHFFFAOYSA-N	515490	N-(4-acryloyl-2,2-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-51	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515490	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515490&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611363	461601598							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082060	C=CC(=O)N[C@@H]1CCCN(C1)C(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C23H26N4O3/c1-2-20(28)25-17-5-3-10-26(13-17)22(30)16-7-6-15-11-19-21(29)24-14-23(8-4-9-23)27(19)18(15)12-16/h2,6-7,11-12,17H,1,3-5,8-10,13-14H2,(H,24,29)(H,25,28)/t17-/m1/s1	WWUCXFCODJTJIW-QGZVFWFLSA-N	515491	(R)&#151;N-(1-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-ylcarbonyl)piperidin-3-yl)acrylamide::US11098061, Compound V-52	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515491	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515491&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611337	461601599							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082061	Cc1ccc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)cc1NC(=O)C=C	InChI=1S/C25H24N4O3/c1-3-22(30)28-19-13-18(8-5-15(19)2)27-23(31)17-7-6-16-11-21-24(32)26-14-25(9-4-10-25)29(21)20(16)12-17/h3,5-8,11-13H,1,4,9-10,14H2,2H3,(H,26,32)(H,27,31)(H,28,30)	IUTMFOKYMHOJEG-UHFFFAOYSA-N	515492	N-(3-acrylamido-4-methylphenyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-53	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515492	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515492&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611204	461601600							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082062	Fc1ccc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)cc1NC(=O)C=C	InChI=1S/C24H21FN4O3/c1-2-21(30)28-18-12-16(6-7-17(18)25)27-22(31)15-5-4-14-10-20-23(32)26-13-24(8-3-9-24)29(20)19(14)11-15/h2,4-7,10-12H,1,3,8-9,13H2,(H,26,32)(H,27,31)(H,28,30)	OCTGBZAQMYNTPG-UHFFFAOYSA-N	515493	N-(3-acrylamido-4-fluorophenyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-54	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515493&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611232	461601601							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082063	Fc1ccc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)cc1NC(=O)C=C	InChI=1S/C24H21FN4O3/c1-2-21(30)28-18-12-16(6-7-17(18)25)27-22(31)15-5-4-14-10-20-23(32)26-13-24(8-3-9-24)29(20)19(14)11-15/h2,4-7,10-12H,1,3,8-9,13H2,(H,26,32)(H,27,31)(H,28,30)	OCTGBZAQMYNTPG-UHFFFAOYSA-N	515493	N-(3-acrylamido-4-fluorophenyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-54	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515493	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515493&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611232	461601601							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082064	C=CC(=O)NC1CCCC1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C23H26N4O3/c1-2-20(28)25-16-5-3-6-17(16)26-21(29)15-8-7-14-11-19-22(30)24-13-23(9-4-10-23)27(19)18(14)12-15/h2,7-8,11-12,16-17H,1,3-6,9-10,13H2,(H,24,30)(H,25,28)(H,26,29)	QHLRAPLVBMBYHD-UHFFFAOYSA-N	515494	N-cis-(2-acrylamidocyclopentyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-55::US11098061, Compound V-56	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611210	461601602							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082065	C=CC(=O)NC1CCCC1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C23H26N4O3/c1-2-20(28)25-16-5-3-6-17(16)26-21(29)15-8-7-14-11-19-22(30)24-13-23(9-4-10-23)27(19)18(14)12-15/h2,7-8,11-12,16-17H,1,3-6,9-10,13H2,(H,24,30)(H,25,28)(H,26,29)	QHLRAPLVBMBYHD-UHFFFAOYSA-N	515494	N-cis-(2-acrylamidocyclopentyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-55::US11098061, Compound V-56	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611210	461601602							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082066	C=CC(=O)NC1CCCC1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C23H26N4O3/c1-2-20(28)25-16-5-3-6-17(16)26-21(29)15-8-7-14-11-19-22(30)24-13-23(9-4-10-23)27(19)18(14)12-15/h2,7-8,11-12,16-17H,1,3-6,9-10,13H2,(H,24,30)(H,25,28)(H,26,29)	QHLRAPLVBMBYHD-UHFFFAOYSA-N	515494	N-cis-(2-acrylamidocyclopentyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-55::US11098061, Compound V-56	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515494	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515494&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611210	461601602							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082067	C=CC(=O)Nc1ncccc1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C23H21N5O3/c1-2-19(29)27-20-16(5-3-10-24-20)26-21(30)15-7-6-14-11-18-22(31)25-13-23(8-4-9-23)28(18)17(14)12-15/h2-3,5-7,10-12H,1,4,8-9,13H2,(H,25,31)(H,26,30)(H,24,27,29)	XLGKXBZWPMUGNC-UHFFFAOYSA-N	515496	N-(2-acrylamidopyridin-3-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-57	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515496&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611203	461601603							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082068	C=CC(=O)Nc1ncccc1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C23H21N5O3/c1-2-19(29)27-20-16(5-3-10-24-20)26-21(30)15-7-6-14-11-18-22(31)25-13-23(8-4-9-23)28(18)17(14)12-15/h2-3,5-7,10-12H,1,4,8-9,13H2,(H,25,31)(H,26,30)(H,24,27,29)	XLGKXBZWPMUGNC-UHFFFAOYSA-N	515496	N-(2-acrylamidopyridin-3-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-57	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515496	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515496&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611203	461601603							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082069	CC1(C)COc2ccc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)cc2N1C(=O)C=C	InChI=1S/C28H28N4O4/c1-4-24(33)32-21-14-19(8-9-23(21)36-16-27(32,2)3)30-25(34)18-7-6-17-12-22-26(35)29-15-28(10-5-11-28)31(22)20(17)13-18/h4,6-9,12-14H,1,5,10-11,15-16H2,2-3H3,(H,29,35)(H,30,34)	QDGDFVYWOGDQIH-UHFFFAOYSA-N	515497	N-(4-acryloyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-58	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515497&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611214	461601604							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082070	CC1(C)COc2ccc(NC(=O)c3ccc4cc5C(=O)NCC6(CCC6)n5c4c3)cc2N1C(=O)C=C	InChI=1S/C28H28N4O4/c1-4-24(33)32-21-14-19(8-9-23(21)36-16-27(32,2)3)30-25(34)18-7-6-17-12-22-26(35)29-15-28(10-5-11-28)31(22)20(17)13-18/h4,6-9,12-14H,1,5,10-11,15-16H2,2-3H3,(H,29,35)(H,30,34)	QDGDFVYWOGDQIH-UHFFFAOYSA-N	515497	N-(4-acryloyl-3,3-dimethyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indole]-7&#8242;-carboxamide::US11098061, Compound V-58	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515497	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515497&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611214	461601604							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082071	C=CC(=O)Nc1ccc2[nH]c(nc2c1)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H21N5O2/c1-2-21(30)26-16-6-7-17-18(12-16)28-22(27-17)15-5-4-14-10-20-23(31)25-13-24(8-3-9-24)29(20)19(14)11-15/h2,4-7,10-12H,1,3,8-9,13H2,(H,25,31)(H,26,30)(H,27,28)	FMSDCACCGAKHRV-UHFFFAOYSA-N	515498	N-(2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)-1H-benzo[d]imidazol-5-yl)acrylamide::US11098061, Compound V-59	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515498	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515498&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611227	461601605							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082072	C=CC(=O)Nc1ccc2oc(nc2c1)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H20N4O3/c1-2-21(29)26-16-6-7-20-17(12-16)27-23(31-20)15-5-4-14-10-19-22(30)25-13-24(8-3-9-24)28(19)18(14)11-15/h2,4-7,10-12H,1,3,8-9,13H2,(H,25,30)(H,26,29)	HPGPISZQLWBXIQ-UHFFFAOYSA-N	515499	N-(2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-5-yl)acrylamide::US11098061, Compound V-60	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515499	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515499&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611249	461601606							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082073	CN1CCC(CC1)c1cc(NC(=O)C=C)c2nc(oc2c1)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C30H31N5O3/c1-3-26(36)32-22-13-21(18-7-11-34(2)12-8-18)16-25-27(22)33-29(38-25)20-6-5-19-14-24-28(37)31-17-30(9-4-10-30)35(24)23(19)15-20/h3,5-6,13-16,18H,1,4,7-12,17H2,2H3,(H,31,37)(H,32,36)	FYPGCMVMVSFILQ-UHFFFAOYSA-N	515500	N-(6-(1-methylpiperidin-4-yl)-2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-61	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515500&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611252	461601607							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082074	CN1CCC(CC1)c1cc(NC(=O)C=C)c2nc(oc2c1)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C30H31N5O3/c1-3-26(36)32-22-13-21(18-7-11-34(2)12-8-18)16-25-27(22)33-29(38-25)20-6-5-19-14-24-28(37)31-17-30(9-4-10-30)35(24)23(19)15-20/h3,5-6,13-16,18H,1,4,7-12,17H2,2H3,(H,31,37)(H,32,36)	FYPGCMVMVSFILQ-UHFFFAOYSA-N	515500	N-(6-(1-methylpiperidin-4-yl)-2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-61	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515500	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515500&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611252	461601607							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082075	Clc1cc(NC(=O)C=C)c2nc(oc2c1)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H19ClN4O3/c1-2-20(30)27-16-10-15(25)11-19-21(16)28-23(32-19)14-5-4-13-8-18-22(31)26-12-24(6-3-7-24)29(18)17(13)9-14/h2,4-5,8-11H,1,3,6-7,12H2,(H,26,31)(H,27,30)	ITPBZWGTLCWICH-UHFFFAOYSA-N	515501	N-(6-chloro-2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-62	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515501&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611250	461601608							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082076	Clc1cc(NC(=O)C=C)c2nc(oc2c1)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H19ClN4O3/c1-2-20(30)27-16-10-15(25)11-19-21(16)28-23(32-19)14-5-4-13-8-18-22(31)26-12-24(6-3-7-24)29(18)17(13)9-14/h2,4-5,8-11H,1,3,6-7,12H2,(H,26,31)(H,27,30)	ITPBZWGTLCWICH-UHFFFAOYSA-N	515501	N-(6-chloro-2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-62	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515501	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515501&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611250	461601608							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082077	C=CC(=O)Nc1cccc2[nH]c(nc12)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H21N5O2/c1-2-20(30)26-16-5-3-6-17-21(16)28-22(27-17)15-8-7-14-11-19-23(31)25-13-24(9-4-10-24)29(19)18(14)12-15/h2-3,5-8,11-12H,1,4,9-10,13H2,(H,25,31)(H,26,30)(H,27,28)	GPCQYXZGXCLPLT-UHFFFAOYSA-N	515502	N-(2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)-1H-benzo[d]imidazol-4-yl)acrylamide::US11098061, Compound V-63	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515502&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611251	461601609							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082078	C=CC(=O)Nc1cccc2[nH]c(nc12)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H21N5O2/c1-2-20(30)26-16-5-3-6-17-21(16)28-22(27-17)15-8-7-14-11-19-23(31)25-13-24(9-4-10-24)29(19)18(14)12-15/h2-3,5-8,11-12H,1,4,9-10,13H2,(H,25,31)(H,26,30)(H,27,28)	GPCQYXZGXCLPLT-UHFFFAOYSA-N	515502	N-(2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)-1H-benzo[d]imidazol-4-yl)acrylamide::US11098061, Compound V-63	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515502	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515502&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611251	461601609							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082079	C=CC(=O)NC1CCCCC1NC(=O)c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H28N4O3/c1-2-21(29)26-17-6-3-4-7-18(17)27-22(30)16-9-8-15-12-20-23(31)25-14-24(10-5-11-24)28(20)19(15)13-16/h2,8-9,12-13,17-18H,1,3-7,10-11,14H2,(H,25,31)(H,26,29)(H,27,30)	LWVJZQMVANOTLN-UHFFFAOYSA-N	515485	BDBM515503::Cis-N-(2-acrylamidocyclohexyl)-1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino[1,2-a]indole]-7&#8242;-carboxamide (racemic)::US11098061, Compound V-46	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515485	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515485&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611165	461601593							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082080	Cc1ccc2oc(nc2c1NC(=O)C=C)-c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C22H18N4O3/c1-3-18(27)24-19-12(2)4-7-17-20(19)25-22(29-17)14-6-5-13-10-16-21(28)23-8-9-26(16)15(13)11-14/h3-7,10-11H,1,8-9H2,2H3,(H,23,28)(H,24,27)	MMRFCFVVJYQGCO-UHFFFAOYSA-N	515504	US11098061, Compound V-26	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515504&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462012	461601611							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082081	Cc1ccc2oc(nc2c1NC(=O)C=C)-c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C22H18N4O3/c1-3-18(27)24-19-12(2)4-7-17-20(19)25-22(29-17)14-6-5-13-10-16-21(28)23-8-9-26(16)15(13)11-14/h3-7,10-11H,1,8-9H2,2H3,(H,23,28)(H,24,27)	MMRFCFVVJYQGCO-UHFFFAOYSA-N	515504	US11098061, Compound V-26	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515504	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515504&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462012	461601611							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082082	C=CC(=O)Nc1cccc2oc(nc12)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H20N4O3/c1-2-20(29)26-16-5-3-6-19-21(16)27-23(31-19)15-8-7-14-11-18-22(30)25-13-24(9-4-10-24)28(18)17(14)12-15/h2-3,5-8,11-12H,1,4,9-10,13H2,(H,25,30)(H,26,29)	NFUFCCCGLJXMRT-UHFFFAOYSA-N	515505	N-(2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-39	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515505&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611158	461601612							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082083	C=CC(=O)Nc1cccc2oc(nc12)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C24H20N4O3/c1-2-20(29)26-16-5-3-6-19-21(16)27-23(31-19)15-8-7-14-11-18-22(30)25-13-24(9-4-10-24)28(18)17(14)12-15/h2-3,5-8,11-12H,1,4,9-10,13H2,(H,25,30)(H,26,29)	NFUFCCCGLJXMRT-UHFFFAOYSA-N	515505	N-(2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-39	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515505	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515505&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611158	461601612							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082084	C=CC(=O)Nc1cccc2oc(nc12)-c1ccc2cc3C(=O)NCCn3c2c1	InChI=1S/C21H16N4O3/c1-2-18(26)23-14-4-3-5-17-19(14)24-21(28-17)13-7-6-12-10-16-20(27)22-8-9-25(16)15(12)11-13/h2-7,10-11H,1,8-9H2,(H,22,27)(H,23,26)	HDFPURXHMZRLDD-UHFFFAOYSA-N	515506	N-(2-(1-oxo-1,2,3,4-tetrahydropyrazino[1,2-a]indol-7-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-31	MAP kinase-activated protein kinase 2	Homo sapiens		 750							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515506	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515506&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462295	461601613							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1082085	Cc1ccc2oc(nc2c1NC(=O)C=C)-c1ccc2cc3C(=O)NCC4(CCC4)n3c2c1	InChI=1S/C25H22N4O3/c1-3-20(30)27-21-14(2)5-8-19-22(21)28-24(32-19)16-7-6-15-11-18-23(31)26-13-25(9-4-10-25)29(18)17(15)12-16/h3,5-8,11-12H,1,4,9-10,13H2,2H3,(H,26,31)(H,27,30)	IBSIOGTXBJVBJG-UHFFFAOYSA-N	515481	N-(5-methyl-2-(1&#8242;-oxo-2&#8242;,3&#8242;-dihydro-1&#8242;H-spiro[cyclobutane-1,4&#8242;-pyrazino [1,2-a]indol]-7&#8242;-yl)benzo[d]oxazol-4-yl)acrylamide::US11098061, Compound V-12	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515481	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515481&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611175	461601589							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081868	COc1ccc(cc1NC(=O)C=C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515378	US11098061, Compound I-1	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515378&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301835	461601487							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081869	COc1ccc(cc1NC(=O)C=C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515378	US11098061, Compound I-1	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515378	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515378&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301835	461601487							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081870	Fc1ccc(cc1NC(=O)C=C)-c1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515379	US11098061, Compound I-8	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515379&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301993	461601488							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081871	Fc1ccc(cc1NC(=O)C=C)-c1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515379	US11098061, Compound I-8	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515379	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515379&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301993	461601488							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081872	COCCOc1ccc(cc1NC(=O)C=C)-c1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515380	US11098061, Compound I-3	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515380&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611121	461601489							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081873	COCCOc1ccc(cc1NC(=O)C=C)-c1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515380	US11098061, Compound I-3	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515380	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515380&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611121	461601489							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081874	C=CC(=O)Nc1ccccc1C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515381	US11098061, Compound I-4	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515381&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301989	461601490							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081875	C=CC(=O)Nc1ccccc1C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515381	US11098061, Compound I-4	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515381	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515381&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301989	461601490							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081876	C=CC(=O)Nc1ccccc1Nc1nccc(n1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515382	US11098061, Compound I-5	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515382	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515382&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611120	461601491							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081877	C=CC(=O)Nc1cccc(c1)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515383	US11098061, Compound I-6	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515383	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515383&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301991	461601492							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081878	COCCOc1ccc(cc1NC(=O)C=C)-c1nccc(n1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515384	US11098061, Compound I-7	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515384&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301992	461601493							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081879	COCCOc1ccc(cc1NC(=O)C=C)-c1nccc(n1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515384	US11098061, Compound I-7	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515384	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515384&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301992	461601493							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081880	FC(F)(F)c1cc(NC(=O)C=C)cc(c1)-c1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515385	US11098061, Compound I-9	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515385&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86302140	461601494							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081881	FC(F)(F)c1cc(NC(=O)C=C)cc(c1)-c1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515385	US11098061, Compound I-9	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515385	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515385&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86302140	461601494							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081882	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515386	US11098061, Compound I-10	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515386	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515386&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86302141	461601495							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081883	FC(F)(F)Oc1ccc(cc1NC(=O)C=C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515387	US11098061, Compound I-23	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515387&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86299871	461601496							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081884	FC(F)(F)Oc1ccc(cc1NC(=O)C=C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515387	US11098061, Compound I-23	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515387	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515387&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86299871	461601496							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081885	Fc1ccc(cc1NC(=O)C=C)C(=O)Nc1cc(ccn1)-c1cc2c([nH]1)C1(CCCNC1)CNC2=O			515388	US11098061, Compound I-24	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515388	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515388&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86299872	461601497							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081886	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C28H30N6O2/c1-3-25(35)31-23-14-17(5-7-24(23)34-12-10-33(2)11-13-34)22-15-20-18(16-30-22)4-6-19-26-21(32-27(19)20)8-9-29-28(26)36/h3,5,7,14-16,32H,1,4,6,8-13H2,2H3,(H,29,36)(H,31,35)	ASLPRZKKTQSKLN-UHFFFAOYSA-N	515389	US11098061, Compound II-1	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515389&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300019	461601498							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081887	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C28H30N6O2/c1-3-25(35)31-23-14-17(5-7-24(23)34-12-10-33(2)11-13-34)22-15-20-18(16-30-22)4-6-19-26-21(32-27(19)20)8-9-29-28(26)36/h3,5,7,14-16,32H,1,4,6,8-13H2,2H3,(H,29,36)(H,31,35)	ASLPRZKKTQSKLN-UHFFFAOYSA-N	515389	US11098061, Compound II-1	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515389	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515389&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300019	461601498							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081888	COc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C24H22N4O3/c1-3-21(29)27-19-10-13(5-7-20(19)31-2)18-11-16-14(12-26-18)4-6-15-22-17(28-23(15)16)8-9-25-24(22)30/h3,5,7,10-12,28H,1,4,6,8-9H2,2H3,(H,25,30)(H,27,29)	KFDCNUCEBJWIIJ-UHFFFAOYSA-N	515390	US11098061, Compound II-2	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515390&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300021	461601499							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081889	COc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C24H22N4O3/c1-3-21(29)27-19-10-13(5-7-20(19)31-2)18-11-16-14(12-26-18)4-6-15-22-17(28-23(15)16)8-9-25-24(22)30/h3,5,7,10-12,28H,1,4,6,8-9H2,2H3,(H,25,30)(H,27,29)	KFDCNUCEBJWIIJ-UHFFFAOYSA-N	515390	US11098061, Compound II-2	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515390	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515390&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300021	461601499							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081890	Fc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C23H19FN4O2/c1-2-20(29)27-19-9-12(4-6-16(19)24)18-10-15-13(11-26-18)3-5-14-21-17(28-22(14)15)7-8-25-23(21)30/h2,4,6,9-11,28H,1,3,5,7-8H2,(H,25,30)(H,27,29)	YEYWIHYWNKGREK-UHFFFAOYSA-N	515391	US11098061, Compound II-3	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515391&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300169	461601500							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081891	Fc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C23H19FN4O2/c1-2-20(29)27-19-9-12(4-6-16(19)24)18-10-15-13(11-26-18)3-5-14-21-17(28-22(14)15)7-8-25-23(21)30/h2,4,6,9-11,28H,1,3,5,7-8H2,(H,25,30)(H,27,29)	YEYWIHYWNKGREK-UHFFFAOYSA-N	515391	US11098061, Compound II-3	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515391	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515391&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300169	461601500							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081892	COc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C23H21N5O3/c1-3-19(29)27-18-8-13(11-26-23(18)31-2)17-9-15-12(10-25-17)4-5-14-20-16(28-21(14)15)6-7-24-22(20)30/h3,8-11,28H,1,4-7H2,2H3,(H,24,30)(H,27,29)	ZHBPSQAVWUMENJ-UHFFFAOYSA-N	515392	US11098061, Compound II-4	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515392&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611315	461601501							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081893	COc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C23H21N5O3/c1-3-19(29)27-18-8-13(11-26-23(18)31-2)17-9-15-12(10-25-17)4-5-14-20-16(28-21(14)15)6-7-24-22(20)30/h3,8-11,28H,1,4-7H2,2H3,(H,24,30)(H,27,29)	ZHBPSQAVWUMENJ-UHFFFAOYSA-N	515392	US11098061, Compound II-4	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515392&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611315	461601501							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081894	COc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C25H23N5O3/c1-3-20(31)28-18-8-14(12-27-24(18)33-2)17-9-16-13(11-26-17)4-5-15-21-19(29-22(15)16)10-25(6-7-25)30-23(21)32/h3,8-9,11-12,29H,1,4-7,10H2,2H3,(H,28,31)(H,30,32)	SWBSWBWZAUQKFJ-UHFFFAOYSA-N	515393	US11098061, Compound II-5	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515393&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300020	461601502							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081895	COc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C25H23N5O3/c1-3-20(31)28-18-8-14(12-27-24(18)33-2)17-9-16-13(11-26-17)4-5-15-21-19(29-22(15)16)10-25(6-7-25)30-23(21)32/h3,8-9,11-12,29H,1,4-7,10H2,2H3,(H,28,31)(H,30,32)	SWBSWBWZAUQKFJ-UHFFFAOYSA-N	515393	US11098061, Compound II-5	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515393&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300020	461601502							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081896	Fc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C25H21FN4O2/c1-2-21(31)28-19-9-13(4-6-17(19)26)18-10-16-14(12-27-18)3-5-15-22-20(29-23(15)16)11-25(7-8-25)30-24(22)32/h2,4,6,9-10,12,29H,1,3,5,7-8,11H2,(H,28,31)(H,30,32)	STOSLXGWDSQMDT-UHFFFAOYSA-N	515394	US11098061, Compound II-6	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515394&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300314	461601503							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081897	Fc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C25H21FN4O2/c1-2-21(31)28-19-9-13(4-6-17(19)26)18-10-16-14(12-27-18)3-5-15-22-20(29-23(15)16)11-25(7-8-25)30-24(22)32/h2,4,6,9-10,12,29H,1,3,5,7-8,11H2,(H,28,31)(H,30,32)	STOSLXGWDSQMDT-UHFFFAOYSA-N	515394	US11098061, Compound II-6	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515394&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300314	461601503							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081898	COCCOc1ccc(cc1NC(=O)C=C)-c1cc2-c3c(CCc2cn1)c1c(CC2(CC2)NC1=O)n3C	InChI=1S/C29H30N4O4/c1-4-25(34)31-22-13-17(6-8-24(22)37-12-11-36-3)21-14-20-18(16-30-21)5-7-19-26-23(33(2)27(19)20)15-29(9-10-29)32-28(26)35/h4,6,8,13-14,16H,1,5,7,9-12,15H2,2-3H3,(H,31,34)(H,32,35)	AXXDETOCVQDQEN-UHFFFAOYSA-N	515395	US11098061, Compound II-7	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515395	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515395&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611331	461601504							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081899	COCCOc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C27H27N5O4/c1-3-22(33)30-20-10-16(14-29-26(20)36-9-8-35-2)19-11-18-15(13-28-19)4-5-17-23-21(31-24(17)18)12-27(6-7-27)32-25(23)34/h3,10-11,13-14,31H,1,4-9,12H2,2H3,(H,30,33)(H,32,34)	JOELFUIPSXSCLR-UHFFFAOYSA-N	515396	US11098061, Compound II-8	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515396&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300170	461601505							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081900	COCCOc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C27H27N5O4/c1-3-22(33)30-20-10-16(14-29-26(20)36-9-8-35-2)19-11-18-15(13-28-19)4-5-17-23-21(31-24(17)18)12-27(6-7-27)32-25(23)34/h3,10-11,13-14,31H,1,4-9,12H2,2H3,(H,30,33)(H,32,34)	JOELFUIPSXSCLR-UHFFFAOYSA-N	515396	US11098061, Compound II-8	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515396	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515396&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300170	461601505							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081901	C=CC(=O)N1CCOc2ncc(cc12)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C26H23N5O3/c1-2-21(32)31-7-8-34-25-20(31)9-15(13-28-25)18-10-17-14(12-27-18)3-4-16-22-19(29-23(16)17)11-26(5-6-26)30-24(22)33/h2,9-10,12-13,29H,1,3-8,11H2,(H,30,33)	RUSJKLNLNRTAEY-UHFFFAOYSA-N	515397	US11098061, Compound II-9	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515397&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300171	461601506							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081902	C=CC(=O)N1CCOc2ncc(cc12)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C26H23N5O3/c1-2-21(32)31-7-8-34-25-20(31)9-15(13-28-25)18-10-17-14(12-27-18)3-4-16-22-19(29-23(16)17)11-26(5-6-26)30-24(22)33/h2,9-10,12-13,29H,1,3-8,11H2,(H,30,33)	RUSJKLNLNRTAEY-UHFFFAOYSA-N	515397	US11098061, Compound II-9	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515397	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515397&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300171	461601506							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081903	NCCCOc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C26H27N5O3/c1-2-23(32)30-21-12-15(5-7-22(21)34-11-3-9-27)20-13-18-16(14-29-20)4-6-17-24-19(31-25(17)18)8-10-28-26(24)33/h2,5,7,12-14,31H,1,3-4,6,8-11,27H2,(H,28,33)(H,30,32)	HWRCUSVULODWLP-UHFFFAOYSA-N	515398	US11098061, Compound II-10	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515398&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300172	461601507							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081904	NCCCOc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C26H27N5O3/c1-2-23(32)30-21-12-15(5-7-22(21)34-11-3-9-27)20-13-18-16(14-29-20)4-6-17-24-19(31-25(17)18)8-10-28-26(24)33/h2,5,7,12-14,31H,1,3-4,6,8-11,27H2,(H,28,33)(H,30,32)	HWRCUSVULODWLP-UHFFFAOYSA-N	515398	US11098061, Compound II-10	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515398	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515398&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300172	461601507							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081905	COCCOc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C28H28N4O4/c1-3-24(33)30-21-12-16(5-7-23(21)36-11-10-35-2)20-13-19-17(15-29-20)4-6-18-25-22(31-26(18)19)14-28(8-9-28)32-27(25)34/h3,5,7,12-13,15,31H,1,4,6,8-11,14H2,2H3,(H,30,33)(H,32,34)	IYZIDGRFAPDJJQ-UHFFFAOYSA-N	515399	US11098061, Compound II-11	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515399&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300173	461601508							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081906	COCCOc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C28H28N4O4/c1-3-24(33)30-21-12-16(5-7-23(21)36-11-10-35-2)20-13-19-17(15-29-20)4-6-18-25-22(31-26(18)19)14-28(8-9-28)32-27(25)34/h3,5,7,12-13,15,31H,1,4,6,8-11,14H2,2H3,(H,30,33)(H,32,34)	IYZIDGRFAPDJJQ-UHFFFAOYSA-N	515399	US11098061, Compound II-11	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515399	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515399&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300173	461601508							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081907	C=CC(=O)N1CCOc2ccc(cc12)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C27H24N4O3/c1-2-23(32)31-9-10-34-22-6-4-15(11-21(22)31)19-12-18-16(14-28-19)3-5-17-24-20(29-25(17)18)13-27(7-8-27)30-26(24)33/h2,4,6,11-12,14,29H,1,3,5,7-10,13H2,(H,30,33)	QYFDQMDNVNVYIZ-UHFFFAOYSA-N	515400	US11098061, Compound II-12	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515400&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611126	461601509							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081908	C=CC(=O)N1CCOc2ccc(cc12)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C27H24N4O3/c1-2-23(32)31-9-10-34-22-6-4-15(11-21(22)31)19-12-18-16(14-28-19)3-5-17-24-20(29-25(17)18)13-27(7-8-27)30-26(24)33/h2,4,6,11-12,14,29H,1,3,5,7-10,13H2,(H,30,33)	QYFDQMDNVNVYIZ-UHFFFAOYSA-N	515400	US11098061, Compound II-12	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515400	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515400&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611126	461601509							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081909	COCCOc1ncc(cc1NC(=O)C=C)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C24H24N6O4/c1-3-18(31)28-17-10-14(12-27-24(17)34-9-8-33-2)22-26-11-13-4-5-15-19-16(6-7-25-23(19)32)29-21(15)20(13)30-22/h3,10-12,29H,1,4-9H2,2H3,(H,25,32)(H,28,31)	BSUUDCCUJATZHP-UHFFFAOYSA-N	515401	US11098061, Compound II-13	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515401&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611191	461601510							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081910	COCCOc1ncc(cc1NC(=O)C=C)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C24H24N6O4/c1-3-18(31)28-17-10-14(12-27-24(17)34-9-8-33-2)22-26-11-13-4-5-15-19-16(6-7-25-23(19)32)29-21(15)20(13)30-22/h3,10-12,29H,1,4-9H2,2H3,(H,25,32)(H,28,31)	BSUUDCCUJATZHP-UHFFFAOYSA-N	515401	US11098061, Compound II-13	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515401	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515401&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611191	461601510							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081911	COCCOc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C25H25N5O4/c1-3-21(31)29-20-10-15(13-28-25(20)34-9-8-33-2)19-11-17-14(12-27-19)4-5-16-22-18(30-23(16)17)6-7-26-24(22)32/h3,10-13,30H,1,4-9H2,2H3,(H,26,32)(H,29,31)	RUKQVCQVBPLNNN-UHFFFAOYSA-N	515402	US11098061, Compound II-14	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515402&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			85470939	461601511							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081912	COCCOc1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C25H25N5O4/c1-3-21(31)29-20-10-15(13-28-25(20)34-9-8-33-2)19-11-17-14(12-27-19)4-5-16-22-18(30-23(16)17)6-7-26-24(22)32/h3,10-13,30H,1,4-9H2,2H3,(H,26,32)(H,29,31)	RUKQVCQVBPLNNN-UHFFFAOYSA-N	515402	US11098061, Compound II-14	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515402	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515402&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			85470939	461601511							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081913	COCCOc1ccc(cc1NC(=O)C=C)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C25H25N5O4/c1-3-20(31)28-18-12-14(5-7-19(18)34-11-10-33-2)24-27-13-15-4-6-16-21-17(8-9-26-25(21)32)29-23(16)22(15)30-24/h3,5,7,12-13,29H,1,4,6,8-11H2,2H3,(H,26,32)(H,28,31)	JYTVMTUFTPDSHB-UHFFFAOYSA-N	515403	US11098061, Compound II-15	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515403&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300315	461601512							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081914	COCCOc1ccc(cc1NC(=O)C=C)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C25H25N5O4/c1-3-20(31)28-18-12-14(5-7-19(18)34-11-10-33-2)24-27-13-15-4-6-16-21-17(8-9-26-25(21)32)29-23(16)22(15)30-24/h3,5,7,12-13,29H,1,4,6,8-11H2,2H3,(H,26,32)(H,28,31)	JYTVMTUFTPDSHB-UHFFFAOYSA-N	515403	US11098061, Compound II-15	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515403	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515403&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300315	461601512							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081915	COCCOc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C26H26N4O4/c1-3-23(31)29-21-12-15(5-7-22(21)34-11-10-33-2)20-13-18-16(14-28-20)4-6-17-24-19(30-25(17)18)8-9-27-26(24)32/h3,5,7,12-14,30H,1,4,6,8-11H2,2H3,(H,27,32)(H,29,31)	ARSOPGCCVMBEKP-UHFFFAOYSA-N	515404	US11098061, Compound II-16	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515404&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300318	461601513							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081916	COCCOc1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C26H26N4O4/c1-3-23(31)29-21-12-15(5-7-22(21)34-11-10-33-2)20-13-18-16(14-28-20)4-6-17-24-19(30-25(17)18)8-9-27-26(24)32/h3,5,7,12-14,30H,1,4,6,8-11H2,2H3,(H,27,32)(H,29,31)	ARSOPGCCVMBEKP-UHFFFAOYSA-N	515404	US11098061, Compound II-16	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515404	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515404&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300318	461601513							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081917	C=CC(=O)N1CCOc2ncc(cc12)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C23H20N6O3/c1-2-17(30)29-7-8-32-23-16(29)9-13(11-26-23)21-25-10-12-3-4-14-18-15(5-6-24-22(18)31)27-20(14)19(12)28-21/h2,9-11,27H,1,3-8H2,(H,24,31)	ZWBNERPQLVFQIY-UHFFFAOYSA-N	515405	US11098061, Compound II-17::US11098061, Compound II-19	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515405&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611236	461601514							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081918	C=CC(=O)N1CCOc2ncc(cc12)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C24H21N5O3/c1-2-20(30)29-7-8-32-24-19(29)9-14(12-27-24)18-10-16-13(11-26-18)3-4-15-21-17(28-22(15)16)5-6-25-23(21)31/h2,9-12,28H,1,3-8H2,(H,25,31)	FSBDVXLPJWRJGJ-UHFFFAOYSA-N	515406	US11098061, Compound II-18	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515406	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515406&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300319	461601515							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081919	C=CC(=O)N1CCOc2ncc(cc12)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C23H20N6O3/c1-2-17(30)29-7-8-32-23-16(29)9-13(11-26-23)21-25-10-12-3-4-14-18-15(5-6-24-22(18)31)27-20(14)19(12)28-21/h2,9-11,27H,1,3-8H2,(H,24,31)	ZWBNERPQLVFQIY-UHFFFAOYSA-N	515405	US11098061, Compound II-17::US11098061, Compound II-19	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515405	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515405&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611236	461601514							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081920	C=CC(=O)N1CCOc2ccc(cc12)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C25H22N4O3/c1-2-22(30)29-9-10-32-21-6-4-14(11-20(21)29)19-12-17-15(13-27-19)3-5-16-23-18(28-24(16)17)7-8-26-25(23)31/h2,4,6,11-13,28H,1,3,5,7-10H2,(H,26,31)	TUJDUVAGRHSLCQ-UHFFFAOYSA-N	515408	US11098061, Compound II-20	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515408	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515408&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300317	461601516							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081921	COCCOc1ncc(cc1NC(=O)C=C)-c1nccc(n1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C22H22N6O4/c1-3-19(29)27-18-10-13(12-25-22(18)32-9-8-31-2)20-23-6-5-16(28-20)17-11-14-15(26-17)4-7-24-21(14)30/h3,5-6,10-12,26H,1,4,7-9H2,2H3,(H,24,30)(H,27,29)	IDLFVDWLPRVPGG-UHFFFAOYSA-N	515409	US11098061, Compound II-21	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515409	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515409&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90462286	461601517							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081922	COCCOc1ccc(cc1NC(=O)C=C)-c1nccc(n1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C23H23N5O4/c1-3-21(29)27-19-12-14(4-5-20(19)32-11-10-31-2)22-24-8-7-17(28-22)18-13-15-16(26-18)6-9-25-23(15)30/h3-5,7-8,12-13,26H,1,6,9-11H2,2H3,(H,25,30)(H,27,29)	SKFOIXNAPUYXAM-UHFFFAOYSA-N	515410	US11098061, Compound II-22	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515410	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515410&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300017	461601518							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081923	C=CC(=O)N1CCOc2ncc(cc12)-c1nccc(n1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C21H18N6O3/c1-2-18(28)27-7-8-30-21-17(27)9-12(11-24-21)19-22-5-4-15(26-19)16-10-13-14(25-16)3-6-23-20(13)29/h2,4-5,9-11,25H,1,3,6-8H2,(H,23,29)	UAHNIHOVYIUPHI-UHFFFAOYSA-N	515411	US11098061, Compound II-23	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515411	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515411&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300018	461601519							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081924	C=CC(=O)N1CCOc2ccc(cc12)-c1ncc2CCc3c([nH]c4CCNC(=O)c34)-c2n1	InChI=1S/C24H21N5O3/c1-2-19(30)29-9-10-32-18-6-4-13(11-17(18)29)23-26-12-14-3-5-15-20-16(7-8-25-24(20)31)27-22(15)21(14)28-23/h2,4,6,11-12,27H,1,3,5,7-10H2,(H,25,31)	VXNMYBBOBZATEJ-UHFFFAOYSA-N	515412	US11098061, Compound II-24	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515412	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515412&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300602	461601520							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081925	C=CC(=O)N1CCOc2ccc(cc12)-c1nccc(n1)-c1cc2c(CCNC2=O)[nH]1	InChI=1S/C22H19N5O3/c1-2-20(28)27-9-10-30-19-4-3-13(11-18(19)27)21-23-7-6-16(26-21)17-12-14-15(25-17)5-8-24-22(14)29/h2-4,6-7,11-12,25H,1,5,8-10H2,(H,24,29)	KHTHUDOBYGYDKS-UHFFFAOYSA-N	515413	US11098061, Compound II-25	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515413	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515413&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611285	461601521							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081926	CN1CCN(CC1)c1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C27H29N7O2/c1-3-23(35)31-22-12-17(15-30-26(22)34-10-8-33(2)9-11-34)21-13-19-16(14-29-21)4-5-18-24-20(32-25(18)19)6-7-28-27(24)36/h3,12-15,32H,1,4-11H2,2H3,(H,28,36)(H,31,35)	SVNKSDWFQIEQEV-UHFFFAOYSA-N	515414	US11098061, Compound II-26	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515414&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300459	461601522							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081927	CN1CCN(CC1)c1ncc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CCNC(=O)c4c3CCc2cn1	InChI=1S/C27H29N7O2/c1-3-23(35)31-22-12-17(15-30-26(22)34-10-8-33(2)9-11-34)21-13-19-16(14-29-21)4-5-18-24-20(32-25(18)19)6-7-28-27(24)36/h3,12-15,32H,1,4-11H2,2H3,(H,28,36)(H,31,35)	SVNKSDWFQIEQEV-UHFFFAOYSA-N	515414	US11098061, Compound II-26	MAP kinase-activated protein kinase 2	Homo sapiens				 300					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515414	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515414&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300459	461601522							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081928	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C30H32N6O2/c1-3-26(37)32-23-14-18(5-7-25(23)36-12-10-35(2)11-13-36)22-15-21-19(17-31-22)4-6-20-27-24(33-28(20)21)16-30(8-9-30)34-29(27)38/h3,5,7,14-15,17,33H,1,4,6,8-13,16H2,2H3,(H,32,37)(H,34,38)	CLCQTJAUFRUWCM-UHFFFAOYSA-N	515415	US11098061, Compound II-27	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515415&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611129	461601523							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081929	CN1CCN(CC1)c1ccc(cc1NC(=O)C=C)-c1cc2-c3[nH]c4CC5(CC5)NC(=O)c4c3CCc2cn1	InChI=1S/C30H32N6O2/c1-3-26(37)32-23-14-18(5-7-25(23)36-12-10-35(2)11-13-36)22-15-21-19(17-31-22)4-6-20-27-24(33-28(20)21)16-30(8-9-30)34-29(27)38/h3,5,7,14-15,17,33H,1,4,6,8-13,16H2,2H3,(H,32,37)(H,34,38)	CLCQTJAUFRUWCM-UHFFFAOYSA-N	515415	US11098061, Compound II-27	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515415	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515415&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611129	461601523							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081930	C=CC(=O)Nc1cccc(c1)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C23H17N3O2/c1-2-21(28)25-15-5-3-4-13(10-15)19-11-17-14(12-24-19)6-7-16-22-18(26-23(16)17)8-9-20(22)27/h2-7,10-12,26H,1,8-9H2,(H,25,28)	IEUVNWVTKUFPCB-UHFFFAOYSA-N	515416	US11098061, Compound II-e-1	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515416&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300753	461601524							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081931	C=CC(=O)Nc1cccc(c1)-c1cc2c3[nH]c4CCC(=O)c4c3ccc2cn1	InChI=1S/C23H17N3O2/c1-2-21(28)25-15-5-3-4-13(10-15)19-11-17-14(12-24-19)6-7-16-22-18(26-23(16)17)8-9-20(22)27/h2-7,10-12,26H,1,8-9H2,(H,25,28)	IEUVNWVTKUFPCB-UHFFFAOYSA-N	515416	US11098061, Compound II-e-1	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515416	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515416&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86300753	461601524							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081932	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnc(C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C24H21N5O2S/c1-4-20(30)29-18-9-14(11-25-13(18)3)16-6-5-15-17(28-16)7-8-19-21(15)22-23(32-19)24(31)27-12(2)10-26-22/h4-9,11-12,26H,1,10H2,2-3H3,(H,27,31)(H,29,30)/t12-/m1/s1	VWPBSTBWDCDXII-GFCCVEGCSA-N	515417	US11098061, Compound III-1	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515417&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301040	461601525							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081933	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnc(C)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C24H21N5O2S/c1-4-20(30)29-18-9-14(11-25-13(18)3)16-6-5-15-17(28-16)7-8-19-21(15)22-23(32-19)24(31)27-12(2)10-26-22/h4-9,11-12,26H,1,10H2,2-3H3,(H,27,31)(H,29,30)/t12-/m1/s1	VWPBSTBWDCDXII-GFCCVEGCSA-N	515417	US11098061, Compound III-1	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515417	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515417&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301040	461601525							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081934	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(F)c(OCC(=O)C=C(C)C)c2)C(=O)N1	InChI=1S/C25H24FN3O4S/c1-13(2)8-17(30)12-33-20-10-16(5-6-19(20)26)29-24(31)15-4-7-21-18(9-15)22-23(34-21)25(32)28-14(3)11-27-22/h4-10,14,27H,11-12H2,1-3H3,(H,28,32)(H,29,31)/t14-/m1/s1	SRNKZSMMBBMEFK-CQSZACIVSA-N	515418	US11098061, Compound III-2	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515418	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515418&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301041	461601526							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081935	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(N3CCCC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C26H27N5O3S/c1-3-22(32)30-19-13-17(7-8-20(19)31-10-4-5-11-31)29-25(33)16-6-9-21-18(12-16)23-24(35-21)26(34)28-15(2)14-27-23/h3,6-9,12-13,15,27H,1,4-5,10-11,14H2,2H3,(H,28,34)(H,29,33)(H,30,32)/t15-/m1/s1	GCWNHHDWOJVRLT-OAHLLOKOSA-N	515419	US11098061, Compound III-3	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515419&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301197	461601527							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081936	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(N3CCCC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C26H27N5O3S/c1-3-22(32)30-19-13-17(7-8-20(19)31-10-4-5-11-31)29-25(33)16-6-9-21-18(12-16)23-24(35-21)26(34)28-15(2)14-27-23/h3,6-9,12-13,15,27H,1,4-5,10-11,14H2,2H3,(H,28,34)(H,29,33)(H,30,32)/t15-/m1/s1	GCWNHHDWOJVRLT-OAHLLOKOSA-N	515419	US11098061, Compound III-3	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515419	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515419&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301197	461601527							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081937	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(N3CCN(C)CC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C27H30N6O3S/c1-4-23(34)31-20-14-18(6-7-21(20)33-11-9-32(3)10-12-33)30-26(35)17-5-8-22-19(13-17)24-25(37-22)27(36)29-16(2)15-28-24/h4-8,13-14,16,28H,1,9-12,15H2,2-3H3,(H,29,36)(H,30,35)(H,31,34)/t16-/m1/s1	YFWDXKSEUWZNNZ-MRXNPFEDSA-N	515420	US11098061, Compound III-4	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515420&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301198	461601528							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081938	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(N3CCN(C)CC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C27H30N6O3S/c1-4-23(34)31-20-14-18(6-7-21(20)33-11-9-32(3)10-12-33)30-26(35)17-5-8-22-19(13-17)24-25(37-22)27(36)29-16(2)15-28-24/h4-8,13-14,16,28H,1,9-12,15H2,2-3H3,(H,29,36)(H,30,35)(H,31,34)/t16-/m1/s1	YFWDXKSEUWZNNZ-MRXNPFEDSA-N	515420	US11098061, Compound III-4	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515420	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515420&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301198	461601528							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081939	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(N3CCNCC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C26H28N6O3S/c1-3-22(33)31-19-13-17(5-6-20(19)32-10-8-27-9-11-32)30-25(34)16-4-7-21-18(12-16)23-24(36-21)26(35)29-15(2)14-28-23/h3-7,12-13,15,27-28H,1,8-11,14H2,2H3,(H,29,35)(H,30,34)(H,31,33)/t15-/m1/s1	MHLGONWMWYHPOU-OAHLLOKOSA-N	515421	US11098061, Compound III-5	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515421&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301196	461601529							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081940	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(N3CCNCC3)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C26H28N6O3S/c1-3-22(33)31-19-13-17(5-6-20(19)32-10-8-27-9-11-32)30-25(34)16-4-7-21-18(12-16)23-24(36-21)26(35)29-15(2)14-28-23/h3-7,12-13,15,27-28H,1,8-11,14H2,2H3,(H,29,35)(H,30,34)(H,31,33)/t15-/m1/s1	MHLGONWMWYHPOU-OAHLLOKOSA-N	515421	US11098061, Compound III-5	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515421	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515421&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301196	461601529							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081941	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C22H19FN4O3S/c1-3-18(28)27-16-9-13(5-6-15(16)23)26-21(29)12-4-7-17-14(8-12)19-20(31-17)22(30)25-11(2)10-24-19/h3-9,11,24H,1,10H2,2H3,(H,25,30)(H,26,29)(H,27,28)/t11-/m1/s1	SEDJQCSMLKXSJV-LLVKDONJSA-N	515422	US11098061, Compound III-6	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515422&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301199	461601530							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081942	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc(F)c(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C22H19FN4O3S/c1-3-18(28)27-16-9-13(5-6-15(16)23)26-21(29)12-4-7-17-14(8-12)19-20(31-17)22(30)25-11(2)10-24-19/h3-9,11,24H,1,10H2,2H3,(H,25,30)(H,26,29)(H,27,28)/t11-/m1/s1	SEDJQCSMLKXSJV-LLVKDONJSA-N	515422	US11098061, Compound III-6	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515422	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515422&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			86301199	461601530							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081943	COCCOc1ccc(NC(=O)c2ccc3sc4c(NC[C@@H](C)NC4=O)c3c2)cc1NC(=O)C=C	InChI=1S/C25H26N4O5S/c1-4-21(30)29-18-12-16(6-7-19(18)34-10-9-33-3)28-24(31)15-5-8-20-17(11-15)22-23(35-20)25(32)27-14(2)13-26-22/h4-8,11-12,14,26H,1,9-10,13H2,2-3H3,(H,27,32)(H,28,31)(H,29,30)/t14-/m1/s1	KJUJUFPQDLAJQR-CQSZACIVSA-N	515423	US11098061, Compound III-7	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515423&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611323	461601531							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081944	COCCOc1ccc(NC(=O)c2ccc3sc4c(NC[C@@H](C)NC4=O)c3c2)cc1NC(=O)C=C	InChI=1S/C25H26N4O5S/c1-4-21(30)29-18-12-16(6-7-19(18)34-10-9-33-3)28-24(31)15-5-8-20-17(11-15)22-23(35-20)25(32)27-14(2)13-26-22/h4-8,11-12,14,26H,1,9-10,13H2,2-3H3,(H,27,32)(H,28,31)(H,29,30)/t14-/m1/s1	KJUJUFPQDLAJQR-CQSZACIVSA-N	515423	US11098061, Compound III-7	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515423	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515423&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611323	461601531							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081945	COCCOc1ccc(cc1NC(=O)C=C)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C27H26N4O4S/c1-4-23(32)31-20-13-16(5-9-21(20)35-12-11-34-3)18-7-6-17-19(30-18)8-10-22-24(17)25-26(36-22)27(33)29-15(2)14-28-25/h4-10,13,15,28H,1,11-12,14H2,2-3H3,(H,29,33)(H,31,32)/t15-/m1/s1	IJBGCAPPPNVVJZ-OAHLLOKOSA-N	515424	US11098061, Compound III-8	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515424&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611299	461601532							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081946	COCCOc1ccc(cc1NC(=O)C=C)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C27H26N4O4S/c1-4-23(32)31-20-13-16(5-9-21(20)35-12-11-34-3)18-7-6-17-19(30-18)8-10-22-24(17)25-26(36-22)27(33)29-15(2)14-28-25/h4-10,13,15,28H,1,11-12,14H2,2-3H3,(H,29,33)(H,31,32)/t15-/m1/s1	IJBGCAPPPNVVJZ-OAHLLOKOSA-N	515424	US11098061, Compound III-8	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515424	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515424&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611299	461601532							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081947	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc3OCCN(C(=O)\C=C\CN(C)C)c3c2)C(=O)N1	InChI=1S/C27H29N5O4S/c1-16-15-28-24-19-13-17(6-9-22(19)37-25(24)27(35)29-16)26(34)30-18-7-8-21-20(14-18)32(11-12-36-21)23(33)5-4-10-31(2)3/h4-9,13-14,16,28H,10-12,15H2,1-3H3,(H,29,35)(H,30,34)/b5-4+/t16-/m1/s1	IQJVSCDNRLUYMS-DWTRPJMMSA-N	515425	US11098061, Compound III-9	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515425	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515425&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611291	461601533							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081948	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccccc2NC(=O)C=C)C(=O)N1	InChI=1S/C22H20N4O3S/c1-3-18(27)25-15-6-4-5-7-16(15)26-21(28)13-8-9-17-14(10-13)19-20(30-17)22(29)24-12(2)11-23-19/h3-10,12,23H,1,11H2,2H3,(H,24,29)(H,25,27)(H,26,28)/t12-/m1/s1	NKFCRVPMRXIUAA-GFCCVEGCSA-N	515426	US11098061, Compound III-10	MAP kinase-activated protein kinase 2	Homo sapiens		 300							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515426&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461728	461601534							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081949	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccccc2NC(=O)C=C)C(=O)N1	InChI=1S/C22H20N4O3S/c1-3-18(27)25-15-6-4-5-7-16(15)26-21(28)13-8-9-17-14(10-13)19-20(30-17)22(29)24-12(2)11-23-19/h3-10,12,23H,1,11H2,2H3,(H,24,29)(H,25,27)(H,26,28)/t12-/m1/s1	NKFCRVPMRXIUAA-GFCCVEGCSA-N	515426	US11098061, Compound III-10	MAP kinase-activated protein kinase 2	Homo sapiens				>1000					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515426	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515426&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461728	461601534							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081950	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc3OCCN(C(=O)C=C)c3c2)C(=O)N1	InChI=1S/C24H22N4O4S/c1-3-20(29)28-8-9-32-18-6-5-15(11-17(18)28)27-23(30)14-4-7-19-16(10-14)21-22(33-19)24(31)26-13(2)12-25-21/h3-7,10-11,13,25H,1,8-9,12H2,2H3,(H,26,31)(H,27,30)/t13-/m1/s1	FKDSVFYFFHBJJO-CYBMUJFWSA-N	515427	US11098061, Compound III-11	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515427&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611127	461601535							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081951	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2ccc3OCCN(C(=O)C=C)c3c2)C(=O)N1	InChI=1S/C24H22N4O4S/c1-3-20(29)28-8-9-32-18-6-5-15(11-17(18)28)27-23(30)14-4-7-19-16(10-14)21-22(33-19)24(31)26-13(2)12-25-21/h3-7,10-11,13,25H,1,8-9,12H2,2H3,(H,26,31)(H,27,30)/t13-/m1/s1	FKDSVFYFFHBJJO-CYBMUJFWSA-N	515427	US11098061, Compound III-11	MAP kinase-activated protein kinase 2	Homo sapiens				<100					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515427	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515427&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117611127	461601535							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081952	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2cccc(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C22H20N4O3S/c1-3-18(27)25-14-5-4-6-15(10-14)26-21(28)13-7-8-17-16(9-13)19-20(30-17)22(29)24-12(2)11-23-19/h3-10,12,23H,1,11H2,2H3,(H,24,29)(H,25,27)(H,26,28)/t12-/m1/s1	UKUJVLDHWTUMBY-GFCCVEGCSA-N	515428	US11098061, Compound III-12	MAP kinase-activated protein kinase 2	Homo sapiens		<100							US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515428&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461935	461601536							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1081953	C[C@@H]1CNc2c(sc3ccc(cc23)C(=O)Nc2cccc(NC(=O)C=C)c2)C(=O)N1	InChI=1S/C22H20N4O3S/c1-3-18(27)25-14-5-4-6-15(10-14)26-21(28)13-7-8-17-16(9-13)19-20(30-17)22(29)24-12(2)11-23-19/h3-10,12,23H,1,11H2,2H3,(H,24,29)(H,25,27)(H,26,28)/t12-/m1/s1	UKUJVLDHWTUMBY-GFCCVEGCSA-N	515428	US11098061, Compound III-12	MAP kinase-activated protein kinase 2	Homo sapiens				 750					US Patent		10.7270/Q2XW4NZW		aid1805866	US11098061	Alexander, MD; McDonald, JJ; Ni, Y; Niu, D; Petter, RC; Qiao, L; Singh, J; Wang, T; Zhu, Z	Celgene CAR LLC	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=515428	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=515428&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			90461935	461601536							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51382794	CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13	InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1	HKSZLNNOFSGOKW-FYTWVXJKSA-N	2579	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one::CHEMBL388978::Staurosporin, 4::Staurosporine::Staurosporine, 8::US9206188, Staurosporine::US9226923, Staurosporine	MAP kinase-activated protein kinase 2	Homo sapiens		 65.9							ChEMBL	10.1016/j.bmc.2018.02.022	10.7270/Q2DJ5KB8	29523467			Hou, W; Ren, Y; Zhang, Z; Sun, H; Ma, Y; Yan, B	Beijing Normal University	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=2579	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=2579&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	STO	1AQ1,1BYG,1E8Z,1NVR,1NXK,1OKY,1Q3D,1QPD,1QPJ,1SM2,1SNU,1STC,1U59,1WVY,1XBC,1XJD,1YHS,2BUJ,2CLQ,2DQ7,2GCD,2HW7,2ITQ,2ITU,2ITW,2NRY,2OIC	44259	8032349	15738	CHEMBL388978		346	C02079	ZINC03814434	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51383688	COCCOc1cc(NC(=O)N2CCCc3cc(CN4CCN(C)CC4=O)c(C=O)nc23)ncc1C#N	InChI=1S/C25H29N7O5/c1-30-6-7-31(23(34)15-30)14-18-10-17-4-3-5-32(24(17)28-20(18)16-33)25(35)29-22-11-21(37-9-8-36-2)19(12-26)13-27-22/h10-11,13,16H,3-9,14-15H2,1-2H3,(H,27,29,35)	LGFNXKJQQVMYQI-UHFFFAOYSA-N	209336	US9266883, 101	MAP kinase-activated protein kinase 2	Homo sapiens		 9400							ChEMBL	10.1021/acs.jmedchem.0c01019	10.7270/Q2FB56MJ	32930584			Fairhurst, RA; Knoepfel, T; Buschmann, N; Leblanc, C; Mah, R; Todorov, M; Nimsgern, P; Ripoche, S; Niklaus, M; Warin, N; Luu, VH; Madoerin, M; Wirth, J; Graus-Porta, D; Weiss, A; Kiffe, M; Wartmann, M; Kinyamu-Akunda, J; Sterker, D; Stamm, C; Adler, F; Buhles, A; Schadt, H; Couttet, P; Blank, J; Galuba, I; Trappe, J; Voshol, J; Ostermann, N; Zou, C; Berghausen, J; Del Rio Espinola, A; Jahnke, W; Furet, P	Novartis Institutes for BioMedical Research	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=209336	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=209336&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118036821	328082431							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51386543	CNCCOc1ccccc1C(C)(C)Nc1nccn(-c2cc(ccc2C)C(=O)NC2CC2)c1=O	InChI=1S/C27H33N5O3/c1-18-9-10-19(25(33)30-20-11-12-20)17-22(18)32-15-13-29-24(26(32)34)31-27(2,3)21-7-5-6-8-23(21)35-16-14-28-4/h5-10,13,15,17,20,28H,11-12,14,16H2,1-4H3,(H,29,31)(H,30,33)	SAZVRXTVWZAHBI-UHFFFAOYSA-N	50560259	CHEMBL4792347	MAP kinase-activated protein kinase 2	Homo sapiens		 6.3							ChEMBL	10.1016/j.bmcl.2020.127412	10.7270/Q2V40ZW0	32717614			Raubo, P; Evans, R; Willis, P	AstraZeneca	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50560259	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50560259&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			25145735	461830651							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180354	OC(=O)c1cccc(c1)-c1n[nH]c2ccccc12	InChI=1S/C14H10N2O2/c17-14(18)10-5-3-4-9(8-10)13-11-6-1-2-7-12(11)15-16-13/h1-8H,(H,15,16)(H,17,18)	FEOVMUZHGLJSAV-UHFFFAOYSA-N	558848	US11370770, Compound 6a	MAP kinase-activated protein kinase 2	Homo sapiens		>27000							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558848&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			165112659	471699491							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180362	Cc1cccc2[nH]nc(-c3ccc(O)cc3)c12	InChI=1S/C14H12N2O/c1-9-3-2-4-12-13(9)14(16-15-12)10-5-7-11(17)8-6-10/h2-8,17H,1H3,(H,15,16)	KPGOHXYOIXHNCD-UHFFFAOYSA-N	558850	US11370770, Compound 6b	MAP kinase-activated protein kinase 2	Homo sapiens		 15000							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558850&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			133693171	471699493							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180370	Oc1ccc(cc1)-c1n[nH]c2ccc(cc12)C(F)(F)F	InChI=1S/C14H9F3N2O/c15-14(16,17)9-3-6-12-11(7-9)13(19-18-12)8-1-4-10(20)5-2-8/h1-7,20H,(H,18,19)	WDSCKUZBXPZKRZ-UHFFFAOYSA-N	558858	US11370770, Compound 6j	MAP kinase-activated protein kinase 2	Homo sapiens		 5300							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558858	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558858&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			136406042	471699501							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180378	OC(=O)c1ccc(cc1)-c1n[nH]c2ccc(cc12)C(F)(F)F	InChI=1S/C15H9F3N2O2/c16-15(17,18)10-5-6-12-11(7-10)13(20-19-12)8-1-3-9(4-2-8)14(21)22/h1-7H,(H,19,20)(H,21,22)	PPEQKTNTCJOCHX-UHFFFAOYSA-N	558862	US11370770, Compound 6n	MAP kinase-activated protein kinase 2	Homo sapiens		>27000							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558862&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			155410758	471699505							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180386	Cc1ccc2[nH]nc(-c3ccc(F)c(CO)c3)c2c1	InChI=1S/C15H13FN2O/c1-9-2-5-14-12(6-9)15(18-17-14)10-3-4-13(16)11(7-10)8-19/h2-7,19H,8H2,1H3,(H,17,18)	JQCLZZOGJRPXOR-UHFFFAOYSA-N	558863	US11370770, Compound 6o	MAP kinase-activated protein kinase 2	Homo sapiens		 5400							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558863&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			56723347	471699506							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180394	Cc1ccc2[nH]nc(-c3ccc4OCOc4c3)c2c1	InChI=1S/C15H12N2O2/c1-9-2-4-12-11(6-9)15(17-16-12)10-3-5-13-14(7-10)19-8-18-13/h2-7H,8H2,1H3,(H,16,17)	ZSSBQAFIQHRGDL-UHFFFAOYSA-N	558864	US11370770, Compound 6p	MAP kinase-activated protein kinase 2	Homo sapiens		 9100							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558864&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			165112665	471699507							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180402	Cc1ccc2[nH]nc(-c3ccc(O)cc3)c2c1	InChI=1S/C14H12N2O/c1-9-2-7-13-12(8-9)14(16-15-13)10-3-5-11(17)6-4-10/h2-8,17H,1H3,(H,15,16)	MYKVSWOFWNECQX-UHFFFAOYSA-N	558865	US11370770, Compound 6q	MAP kinase-activated protein kinase 2	Homo sapiens		 7200							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558865&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			155410618	471699508							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180410	Cc1ccc2[nH]nc(-c3ccc(cc3)C(N)=O)c2c1	InChI=1S/C15H13N3O/c1-9-2-7-13-12(8-9)14(18-17-13)10-3-5-11(6-4-10)15(16)19/h2-8H,1H3,(H2,16,19)(H,17,18)	OPXYKOZRBJVVTD-UHFFFAOYSA-N	558866	US11370770, Compound 6r	MAP kinase-activated protein kinase 2	Homo sapiens		 6100							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558866&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			155410737	471699509							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180418	Cc1ccc2[nH]nc(-c3ccc(cc3)C(O)=O)c2c1	InChI=1S/C15H12N2O2/c1-9-2-7-13-12(8-9)14(17-16-13)10-3-5-11(6-4-10)15(18)19/h2-8H,1H3,(H,16,17)(H,18,19)	SLEUHKWQBRMQOG-UHFFFAOYSA-N	558867	US11370770, Compound 6s	MAP kinase-activated protein kinase 2	Homo sapiens		>27000							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558867&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			155410650	471699510							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180426	OC(=O)c1ccc(cc1)-c1n[nH]c2cc(ccc12)C(F)(F)F	InChI=1S/C15H9F3N2O2/c16-15(17,18)10-5-6-11-12(7-10)19-20-13(11)8-1-3-9(4-2-8)14(21)22/h1-7H,(H,19,20)(H,21,22)	CHYJUWDXSCFHON-UHFFFAOYSA-N	558875	US11370770, Compound 6z	MAP kinase-activated protein kinase 2	Homo sapiens		>27000							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558875&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			165112668	471699518							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180434	Fc1ccc2c(n[nH]c2c1)-c1ccc2OCOc2c1	InChI=1S/C14H9FN2O2/c15-9-2-3-10-11(6-9)16-17-14(10)8-1-4-12-13(5-8)19-7-18-12/h1-6H,7H2,(H,16,17)	XYAAMRRUEGTHMB-UHFFFAOYSA-N	558880	US11370770, Compound 6ee	MAP kinase-activated protein kinase 2	Homo sapiens		 9300							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=558880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=558880&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			165112673	471699523							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1180442	OC(=O)c1ccc(cc1)-c1n[nH]c2cc(F)ccc12	InChI=1S/C14H9FN2O2/c15-10-5-6-11-12(7-10)16-17-13(11)8-1-3-9(4-2-8)14(18)19/h1-7H,(H,16,17)(H,18,19)	JCIIJLGOZRZKPD-UHFFFAOYSA-N	50559798	CHEMBL4758063::US11370770, Compound 6ff	MAP kinase-activated protein kinase 2	Homo sapiens		>27000							US Patent		10.7270/Q2HX1GWD		aid1806622	US11370770	Scheidt, KA; Schiltz, GE; Clutter, MR; Kwong, AJ	NORTHWESTERN UNIVERSITY	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50559798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50559798&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			155410731	461830190							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51444241	CCc1cccc(CC)c1NC(=O)c1ccn-2c1CCc1cnc(Nc3ccc(cc3NC(=O)C=C)N3CCN(C)CC3)nc-21	InChI=1S/C35H40N8O2/c1-5-23-9-8-10-24(6-2)32(23)39-34(45)27-15-16-43-30(27)14-11-25-22-36-35(40-33(25)43)38-28-13-12-26(21-29(28)37-31(44)7-3)42-19-17-41(4)18-20-42/h7-10,12-13,15-16,21-22H,3,5-6,11,14,17-20H2,1-2,4H3,(H,37,44)(H,39,45)(H,36,38,40)	QMTKZAHTDPRIFJ-UHFFFAOYSA-N	50583520	CHEMBL5094006	MAP kinase-activated protein kinase 2	Homo sapiens		>5000							ChEMBL	10.1021/acs.jmedchem.1c01165	10.7270/Q2T157JC	35167750			M Serafim, RA; da Silva Santiago, A; Schwalm, MP; Hu, Z; Dos Reis, CV; Takarada, JE; Mezzomo, P; Massirer, KB; Kudolo, M; Gerstenecker, S; Chaikuad, A; Zender, L; Knapp, S; Laufer, S; Couñago, RM; Gehringer, M	Eberhard Karls University T&#163;bingen	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50583520	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50583520&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			163196379	476028525							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51492091	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccc(C)nc2)C(=O)N1	InChI=1S/C21H18N4OS/c1-11-3-4-13(10-22-11)15-6-5-14-16(25-15)7-8-17-18(14)19-20(27-17)21(26)24-12(2)9-23-19/h3-8,10,12,23H,9H2,1-2H3,(H,24,26)/t12-/m1/s1	CMWRPDHVGMHLSZ-GFCCVEGCSA-N	50395272	CHEMBL1231206	MAP kinase-activated protein kinase 2	Homo sapiens		 2.0							ChEMBL		10.7270/Q22Z19M2	33481605			Xie, Z; Yang, X; Duan, Y; Han, J; Liao, C	Hefei University of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50395272	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50395272&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	B97	3FYJ,6T8X,7NRY	44631903	163344296		CHEMBL1231206	DB07430			ZINC39258365	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51492092	CC(C)(C)CN1CCC(CC1)NC(=O)c1csc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)n4c3c2)n1	InChI=1S/C29H36N6O3S/c1-28(2,3)17-34-11-7-20(8-12-34)31-25(37)21-15-39-27(32-21)33-24(36)19-6-5-18-13-23-26(38)30-16-29(9-4-10-29)35(23)22(18)14-19/h5-6,13-15,20H,4,7-12,16-17H2,1-3H3,(H,30,38)(H,31,37)(H,32,33,36)	MJQUKUIDCUNAAB-UHFFFAOYSA-N	50374681	CHEMBL257834	MAP kinase-activated protein kinase 2	Homo sapiens		 2.0							ChEMBL		10.7270/Q22Z19M2	33481605			Xie, Z; Yang, X; Duan, Y; Han, J; Liao, C	Hefei University of Technology	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50374681	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50374681&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			24882562	160853771		CHEMBL257834				ZINC29127774	1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51524492	COc1ccncc1NC(=O)c1ccnc(NC(=O)C2CC2)c1	InChI=1S/C16H16N4O3/c1-23-13-5-6-17-9-12(13)19-16(22)11-4-7-18-14(8-11)20-15(21)10-2-3-10/h4-10H,2-3H2,1H3,(H,19,22)(H,18,20,21)	NZMAVPMPPORZNT-UHFFFAOYSA-N	50452728	CHEMBL4213175	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL		10.7270/Q2TB1C5P	26751161			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50452728	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50452728&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	3UO	5F94	117072455	433921555							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51524493	O=C(Nc1cc(ccn1)C(=O)Nc1cnccc1-c1ccccc1)C1CC1	InChI=1S/C21H18N4O2/c26-20(15-6-7-15)25-19-12-16(8-11-23-19)21(27)24-18-13-22-10-9-17(18)14-4-2-1-3-5-14/h1-5,8-13,15H,6-7H2,(H,24,27)(H,23,25,26)	LJUDIYPNWBIDNH-UHFFFAOYSA-N	50613392	CHEMBL5270581	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL		10.7270/Q2TB1C5P	26751161			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50613392	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50613392&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			117072456	494503140							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51524494	Fc1ccc(cc1)-c1ccncc1NC(=O)c1ccnc(NC(=O)C2CC2)c1	InChI=1S/C21H17FN4O2/c22-16-5-3-13(4-6-16)17-8-9-23-12-18(17)25-21(28)15-7-10-24-19(11-15)26-20(27)14-1-2-14/h3-12,14H,1-2H2,(H,25,28)(H,24,26,27)	AMINIFOLNFYOOD-UHFFFAOYSA-N	50613393	CHEMBL5288565	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL		10.7270/Q2TB1C5P	26751161			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50613393	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50613393&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118065217	494503141							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51524495	Clc1ccc(cc1)-c1ccncc1NC(=O)c1ccnc(NC(=O)C2CC2)c1	InChI=1S/C21H17ClN4O2/c22-16-5-3-13(4-6-16)17-8-9-23-12-18(17)25-21(28)15-7-10-24-19(11-15)26-20(27)14-1-2-14/h3-12,14H,1-2H2,(H,25,28)(H,24,26,27)	OYNBEDDKSIPEQC-UHFFFAOYSA-N	50613394	CHEMBL5278465	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL		10.7270/Q2TB1C5P	26751161			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50613394	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50613394&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			118070956	494503142							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51523916	CC1CN(CCO1)c1ccncc1NC(=O)c1ccnn2cc(nc12)-c1ccccc1	InChI=1S/C23H22N6O2/c1-16-14-28(11-12-31-16)21-8-9-24-13-19(21)27-23(30)18-7-10-25-29-15-20(26-22(18)29)17-5-3-2-4-6-17/h2-10,13,15-16H,11-12,14H2,1H3,(H,27,30)	MENVSADYTLLXLP-UHFFFAOYSA-N	610463	BDBM610464::BDBM610465::N-(4-(2-Methylmorpholino)pyridin-3-yl)-2-phenylimidazo[1,2-b]pyridazine-8-carboxamide::US10774086, Example 14	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL		10.7270/Q2W95FFW	36950863			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=610463	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=610463&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	UAU	8DJC	134551592	483620628							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51519470	C[C@@H]1CCN(C[C@@H]1n1ccc2cnc3[nH]ccc3c12)C(=O)CC#N	InChI=1S/C18H19N5O/c1-12-4-8-22(16(24)2-6-19)11-15(12)23-9-5-13-10-21-18-14(17(13)23)3-7-20-18/h3,5,7,9-10,12,15H,2,4,8,11H2,1H3,(H,20,21)/t12-,15+/m1/s1	UQVAOELSLJXOMB-DOMZBBRYSA-N	50611755	CHEMBL5281283	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL		10.7270/Q2ZP4BCS	28789911			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611755	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611755&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49779405	494501503							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51519471	C[C@@H]1CCN(C[C@@H]1n1ccc2cnc3[nH]cc(C#N)c3c12)C(=O)CC#N	InChI=1S/C19H18N6O/c1-12-3-6-24(16(26)2-5-20)11-15(12)25-7-4-13-9-22-19-17(18(13)25)14(8-21)10-23-19/h4,7,9-10,12,15H,2-3,6,11H2,1H3,(H,22,23)/t12-,15+/m1/s1	PFZVRMSUBHGEID-DOMZBBRYSA-N	50611758	CHEMBL5273533	MAP kinase-activated protein kinase 2	Homo sapiens		>1000							ChEMBL		10.7270/Q2ZP4BCS	28789911			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50611758	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50611758&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			49779409	494501506							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	1KWP,1NXK,1NY3,2JBO,2JBP,2ONL,2OZA,2P3G,2PZY,3A2C,3FPM,3FYJ,3FYK,3GOK,3KC3,3R2B,3R2Y,3R30,3WI6,4TYH,6TCA,7NRY	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51547467	Fc1ccc(cc1)-c1ccncc1NC(=O)c1ccnc(Nc2ccc(cc2)C#N)n1	InChI=1S/C23H15FN6O/c24-17-5-3-16(4-6-17)19-9-11-26-14-21(19)29-22(31)20-10-12-27-23(30-20)28-18-7-1-15(13-25)2-8-18/h1-12,14H,(H,29,31)(H,27,28,30)	QLWFPXXGZGCHFQ-UHFFFAOYSA-N	50622457	CHEMBL5419652	MAP kinase-activated protein kinase 2	Homo sapiens		>50000							ChEMBL	10.1021/acs.jmedchem.3c00364	10.7270/Q2B56Q46	37235865			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50622457	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50622457&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
51547468	Fc1ccc(Nc2nccc(n2)C(=O)Nc2cnccc2-c2ccc(F)cc2)cc1	InChI=1S/C22H15F2N5O/c23-15-3-1-14(2-4-15)18-9-11-25-13-20(18)28-21(30)19-10-12-26-22(29-19)27-17-7-5-16(24)6-8-17/h1-13H,(H,28,30)(H,26,27,29)	UWQKULXATKCNBV-UHFFFAOYSA-N	50622458	CHEMBL5402829	MAP kinase-activated protein kinase 2	Homo sapiens		>27000							ChEMBL	10.1021/acs.jmedchem.3c00364	10.7270/Q2B56Q46	37235865			n/a	n/a	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50622458	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=50622458&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search											1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433596	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(ncc2F)C#C)C(=O)N1	InChI=1S/C21H14FN5OS/c1-3-16-23-9-12(22)18(27-16)14-5-4-11-13(26-14)6-7-15-17(11)19-20(29-15)21(28)25-10(2)8-24-19/h1,4-7,9-10,24H,8H2,2H3,(H,25,28)/t10-/m1/s1	BVVCWHNWISHTIJ-SNVBAGLBSA-N	688778	(R)-3-(2-ethynyl-5-fluoropyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-1	MAP kinase-activated protein kinase 2	Homo sapiens		 5.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688778	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688778&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542002	504490448							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433597	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)ncc2F)C(=O)N1	InChI=1S/C21H16FN5OS/c1-3-16-23-9-12(22)18(27-16)14-5-4-11-13(26-14)6-7-15-17(11)19-20(29-15)21(28)25-10(2)8-24-19/h3-7,9-10,24H,1,8H2,2H3,(H,25,28)/t10-/m1/s1	QNGCXKWBVKCNQC-SNVBAGLBSA-N	688779	(R)-3-(5-fluoro-2-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-2	MAP kinase-activated protein kinase 2	Homo sapiens		 133							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688779	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688779&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542016	504490449							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433598	CCOCc1cnc(Cl)nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H20ClN5O2S/c1-3-30-10-12-9-25-22(23)28-18(12)15-5-4-13-14(27-15)6-7-16-17(13)19-20(31-16)21(29)26-11(2)8-24-19/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1	ZSNTXLQWXIIDPC-LLVKDONJSA-N	688780	(R)-3-(2-chloro-5-(ethoxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-3	MAP kinase-activated protein kinase 2	Homo sapiens		 107							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688780	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688780&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430031	504490450							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433599	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2C(F)(F)F)C(=O)N1	InChI=1S/C20H13ClF3N5OS/c1-8-6-25-16-14-9-2-3-12(15-10(20(22,23)24)7-26-19(21)29-15)28-11(9)4-5-13(14)31-17(16)18(30)27-8/h2-5,7-8,25H,6H2,1H3,(H,27,30)/t8-/m1/s1	ORBJNMQPHINFEU-MRVPVSSYSA-N	688784	(R)-3-(2-chloro-5-(trifluoromethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-4	MAP kinase-activated protein kinase 2	Homo sapiens		 1.000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688784	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688784&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430032	504490454							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433600	CCOCc1cnc(C=C)nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H23N5O2S/c1-4-19-25-11-14(12-31-5-2)21(29-19)17-7-6-15-16(28-17)8-9-18-20(15)22-23(32-18)24(30)27-13(3)10-26-22/h4,6-9,11,13,26H,1,5,10,12H2,2-3H3,(H,27,30)/t13-/m1/s1	VAVIMUFNSVHOGU-CYBMUJFWSA-N	688785	(R)-3-(5-(ethoxymethyl)-2-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-5	MAP kinase-activated protein kinase 2	Homo sapiens		 7.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688785	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688785&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542241	504490455							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433601	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2C)C(=O)N1	InChI=1S/C20H16ClN5OS/c1-9-7-23-20(21)26-16(9)13-4-3-11-12(25-13)5-6-14-15(11)17-18(28-14)19(27)24-10(2)8-22-17/h3-7,10,22H,8H2,1-2H3,(H,24,27)/t10-/m1/s1	RLLWVHQKAOCCID-SNVBAGLBSA-N	688786	(R)-3-(2-chloro-5-methylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-6	MAP kinase-activated protein kinase 2	Homo sapiens		 912							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688786	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688786&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542323	504490456							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433602	COCc1nc(Cl)cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C21H18ClN5O2S/c1-10-8-23-19-18-11-3-4-13(14-7-16(22)27-17(26-14)9-29-2)25-12(11)5-6-15(18)30-20(19)21(28)24-10/h3-7,10,23H,8-9H2,1-2H3,(H,24,28)/t10-/m1/s1	VDTBAXTXKVTWDU-SNVBAGLBSA-N	688787	(R)-3-(6-chloro-2-(methoxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-7	MAP kinase-activated protein kinase 2	Homo sapiens		 6.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688787	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688787&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430033	504490457							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433603	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(Cl)n2)C(=O)N1	InChI=1S/C19H14ClN5OS/c1-9-8-22-16-15-10-2-3-12(13-6-7-21-19(20)25-13)24-11(10)4-5-14(15)27-17(16)18(26)23-9/h2-7,9,22H,8H2,1H3,(H,23,26)/t9-/m1/s1	AJQHMQBBJOGZKX-SECBINFHSA-N	688788	(R)-3-(2-chloropyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-8	MAP kinase-activated protein kinase 2	Homo sapiens		 75.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688788	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688788&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542010	504490458							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433604	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2C#N)C(=O)N1	InChI=1S/C20H13ClN6OS/c1-9-7-23-17-15-11-2-3-13(16-10(6-22)8-24-20(21)27-16)26-12(11)4-5-14(15)29-18(17)19(28)25-9/h2-5,8-9,23H,7H2,1H3,(H,25,28)/t9-/m1/s1	ODYRRJORIFCZRP-SECBINFHSA-N	688789	(R)-2-chloro-4-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)pyrimidine-5-carbonitrile::US20240190890, Compound I-9	MAP kinase-activated protein kinase 2	Homo sapiens		 97.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688789	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688789&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430034	504490459							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433605	COc1cnc(Cl)nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C20H16ClN5O2S/c1-9-7-22-17-15-10-3-4-12(16-13(28-2)8-23-20(21)26-16)25-11(10)5-6-14(15)29-18(17)19(27)24-9/h3-6,8-9,22H,7H2,1-2H3,(H,24,27)/t9-/m1/s1	NITYTAXELHCBKZ-SECBINFHSA-N	688790	(R)-3-(2-chloro-5-methoxypyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-10	MAP kinase-activated protein kinase 2	Homo sapiens		 291							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688790	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688790&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542318	504490460							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433606	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)ncn2)C(=O)N1	InChI=1S/C19H14ClN5OS/c1-9-7-21-17-16-10-2-3-12(13-6-15(20)23-8-22-13)25-11(10)4-5-14(16)27-18(17)19(26)24-9/h2-6,8-9,21H,7H2,1H3,(H,24,26)/t9-/m1/s1	SIONEJSINFOYIC-SECBINFHSA-N	688791	(R)-3-(6-chloropyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-11	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688791	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688791&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541923	504490461							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433607	CCOCc1cnc(nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C#C	InChI=1S/C24H21N5O2S/c1-4-19-25-11-14(12-31-5-2)21(29-19)17-7-6-15-16(28-17)8-9-18-20(15)22-23(32-18)24(30)27-13(3)10-26-22/h1,6-9,11,13,26H,5,10,12H2,2-3H3,(H,27,30)/t13-/m1/s1	YTBUHAXTIXYOFM-CYBMUJFWSA-N	688792	(R)-3-(5-(ethoxymethyl)-2-ethynylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-12	MAP kinase-activated protein kinase 2	Homo sapiens		 87.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688792	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688792&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430035	504490462							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433608	COCc1nc(C=C)cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H21N5O2S/c1-4-13-9-17(28-19(26-13)11-30-3)16-6-5-14-15(27-16)7-8-18-20(14)21-22(31-18)23(29)25-12(2)10-24-21/h4-9,12,24H,1,10-11H2,2-3H3,(H,25,29)/t12-/m1/s1	DKNMNBDBXUQROL-GFCCVEGCSA-N	688793	(R)-3-(2-(methoxymethyl)-6-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-13	MAP kinase-activated protein kinase 2	Homo sapiens		 1.000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688793	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688793&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430036	504490463							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433609	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(COC3CCNCC3)n2)C(=O)N1	InChI=1S/C25H25ClN6O2S/c1-13-11-28-23-22-15-2-3-17(30-16(15)4-5-19(22)35-24(23)25(33)29-13)18-10-20(26)32-21(31-18)12-34-14-6-8-27-9-7-14/h2-5,10,13-14,27-28H,6-9,11-12H2,1H3,(H,29,33)/t13-/m1/s1	KCZXCVBFVIKSNN-CYBMUJFWSA-N	688794	(R)-3-(6-chloro-2-((piperidin-4-yloxy)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-14	MAP kinase-activated protein kinase 2	Homo sapiens		 12.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688794	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688794&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430037	504490464							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433610	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(COC3CCN(C)CC3)n2)C(=O)N1	InChI=1S/C26H27ClN6O2S/c1-14-12-28-24-23-16-3-4-18(30-17(16)5-6-20(23)36-25(24)26(34)29-14)19-11-21(27)32-22(31-19)13-35-15-7-9-33(2)10-8-15/h3-6,11,14-15,28H,7-10,12-13H2,1-2H3,(H,29,34)/t14-/m1/s1	PLYOAEKORXFQFI-CQSZACIVSA-N	688795	(R)-3-(6-chloro-2-(((1-methylpiperidin-4-yl)oxy)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-15	MAP kinase-activated protein kinase 2	Homo sapiens		 10.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688795	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688795&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430038	504490465							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433611	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(Cl)n2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C24H24ClN7OS/c1-13-12-26-21-20-14-3-4-16(28-15(14)5-6-18(20)34-22(21)23(33)27-13)17-11-19(30-24(25)29-17)32-9-7-31(2)8-10-32/h3-6,11,13,26H,7-10,12H2,1-2H3,(H,27,33)/t13-/m1/s1	RIMMRMIETFRGAU-CYBMUJFWSA-N	688796	(R)-3-(2-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-16	MAP kinase-activated protein kinase 2	Homo sapiens		 26.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688796	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688796&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542278	504490466							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433612	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(n2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C24H24ClN7OS/c1-13-12-26-21-20-14-3-4-16(28-15(14)5-6-18(20)34-22(21)23(33)27-13)17-11-19(25)30-24(29-17)32-9-7-31(2)8-10-32/h3-6,11,13,26H,7-10,12H2,1-2H3,(H,27,33)/t13-/m1/s1	DBYWIAYZCSBVGD-CYBMUJFWSA-N	688797	(R)-3-(6-chloro-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-17	MAP kinase-activated protein kinase 2	Homo sapiens		 137							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688797	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688797&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541927	504490467							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433613	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(C=C)n2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C26H27N7OS/c1-4-21-30-19(13-22(31-21)33-11-9-32(3)10-12-33)18-6-5-16-17(29-18)7-8-20-23(16)24-25(35-20)26(34)28-15(2)14-27-24/h4-8,13,15,27H,1,9-12,14H2,2-3H3,(H,28,34)/t15-/m1/s1	LIRATNHHKKVTIV-OAHLLOKOSA-N	688798	(R)-10-methyl-3-(6-(4-methylpiperazin-1-yl)-2-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-18	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688798	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688798&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430039	504490468							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433614	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(n2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C26H27N7OS/c1-4-16-13-20(31-26(29-16)33-11-9-32(3)10-12-33)19-6-5-17-18(30-19)7-8-21-22(17)23-24(35-21)25(34)28-15(2)14-27-23/h4-8,13,15,27H,1,9-12,14H2,2-3H3,(H,28,34)/t15-/m1/s1	MULTUWLZQOORFJ-OAHLLOKOSA-N	688799	(R)-10-methyl-3-(2-(4-methylpiperazin-1-yl)-6-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-19	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688799	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688799&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430040	504490469							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433615	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2COC2COC2)C(=O)N1	InChI=1S/C23H20ClN5O3S/c1-11-6-25-20-18-14-2-3-16(28-15(14)4-5-17(18)33-21(20)22(30)27-11)19-12(7-26-23(24)29-19)8-32-13-9-31-10-13/h2-5,7,11,13,25H,6,8-10H2,1H3,(H,27,30)/t11-/m1/s1	AYQBDPLXDVKLBH-LLVKDONJSA-N	688800	(R)-3-(2-chloro-5-((oxetan-3-yloxy)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-20	MAP kinase-activated protein kinase 2	Homo sapiens		 224							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688800	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688800&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430041	504490470							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433616	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)ncc2COC2COC2)C(=O)N1	InChI=1S/C25H23N5O3S/c1-3-20-26-9-14(10-33-15-11-32-12-15)22(30-20)18-5-4-16-17(29-18)6-7-19-21(16)23-24(34-19)25(31)28-13(2)8-27-23/h3-7,9,13,15,27H,1,8,10-12H2,2H3,(H,28,31)/t13-/m1/s1	DTYXWUXJUDPYLX-CYBMUJFWSA-N	688801	(R)-10-methyl-3-(5-((oxetan-3-yloxy)methyl)-2-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-21	MAP kinase-activated protein kinase 2	Homo sapiens		 24.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688801	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688801&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430042	504490471							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433617	CCOCc1nc(C=C)cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H23N5O2S/c1-4-14-10-18(29-20(27-14)12-31-5-2)17-7-6-15-16(28-17)8-9-19-21(15)22-23(32-19)24(30)26-13(3)11-25-22/h4,6-10,13,25H,1,5,11-12H2,2-3H3,(H,26,30)/t13-/m1/s1	SILISHPIGXVBCB-CYBMUJFWSA-N	688802	(R)-3-(2-(ethoxymethyl)-6-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-22	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688802	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688802&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542298	504490472							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433618	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(COC3CCOCC3)n2)C(=O)N1	InChI=1S/C25H24ClN5O3S/c1-13-11-27-23-22-15-2-3-17(29-16(15)4-5-19(22)35-24(23)25(32)28-13)18-10-20(26)31-21(30-18)12-34-14-6-8-33-9-7-14/h2-5,10,13-14,27H,6-9,11-12H2,1H3,(H,28,32)/t13-/m1/s1	SJXJFZZGSWNNSX-CYBMUJFWSA-N	688803	(R)-3-(6-chloro-2-(((tetrahydro-2H-pyran-4-yl)oxy)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-23	MAP kinase-activated protein kinase 2	Homo sapiens		 487							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688803	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688803&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430043	504490473							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433619	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2COC2CCOCC2)C(=O)N1	InChI=1S/C25H24ClN5O3S/c1-13-10-27-22-20-16-2-3-18(30-17(16)4-5-19(20)35-23(22)24(32)29-13)21-14(11-28-25(26)31-21)12-34-15-6-8-33-9-7-15/h2-5,11,13,15,27H,6-10,12H2,1H3,(H,29,32)/t13-/m1/s1	QTQKYZVSVALXMF-CYBMUJFWSA-N	688804	(R)-3-(2-chloro-5-(((tetrahydro-2H-pyran-4-yl)oxy)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-24	MAP kinase-activated protein kinase 2	Homo sapiens		 98.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688804	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688804&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430044	504490474							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433620	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)ncc2COC2CCOCC2)C(=O)N1	InChI=1S/C27H27N5O3S/c1-3-22-28-13-16(14-35-17-8-10-34-11-9-17)24(32-22)20-5-4-18-19(31-20)6-7-21-23(18)25-26(36-21)27(33)30-15(2)12-29-25/h3-7,13,15,17,29H,1,8-12,14H2,2H3,(H,30,33)/t15-/m1/s1	PMLDZZCBZCINEQ-OAHLLOKOSA-N	688805	(R)-10-methyl-3-(5-(((tetrahydro-2H-pyran-4-yl)oxy)methyl)-2-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-25	MAP kinase-activated protein kinase 2	Homo sapiens		 43.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688805	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688805&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430045	504490475							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433621	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)ncc2COC2(C)CCC2)C(=O)N1	InChI=1S/C27H27N5O2S/c1-4-21-28-13-16(14-34-27(3)10-5-11-27)23(32-21)19-7-6-17-18(31-19)8-9-20-22(17)24-25(35-20)26(33)30-15(2)12-29-24/h4,6-9,13,15,29H,1,5,10-12,14H2,2-3H3,(H,30,33)/t15-/m1/s1	KIQYISYRKZTJRF-OAHLLOKOSA-N	688806	(R)-10-methyl-3-(5-((1-methylcyclobutoxy)methyl)-2-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-26	MAP kinase-activated protein kinase 2	Homo sapiens		 684							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688806	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688806&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430046	504490476							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433622	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2COC2(C)CCC2)C(=O)N1	InChI=1S/C25H24ClN5O2S/c1-13-10-27-21-19-15-4-5-17(30-16(15)6-7-18(19)34-22(21)23(32)29-13)20-14(11-28-24(26)31-20)12-33-25(2)8-3-9-25/h4-7,11,13,27H,3,8-10,12H2,1-2H3,(H,29,32)/t13-/m1/s1	UOSJXQVWMSVZFT-CYBMUJFWSA-N	688807	(R)-3-(2-chloro-5-((1-methylcyclobutoxy)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-27	MAP kinase-activated protein kinase 2	Homo sapiens		 391							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688807	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688807&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430047	504490477							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433623	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2COC2(C)COC2)C(=O)N1	InChI=1S/C24H22ClN5O3S/c1-12-7-26-20-18-14-3-4-16(29-15(14)5-6-17(18)34-21(20)22(31)28-12)19-13(8-27-23(25)30-19)9-33-24(2)10-32-11-24/h3-6,8,12,26H,7,9-11H2,1-2H3,(H,28,31)/t12-/m1/s1	GUJCSSPNTAFYOP-GFCCVEGCSA-N	688808	(R)-3-(2-chloro-5-(((3-methyloxetan-3-yl)oxy)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-28	MAP kinase-activated protein kinase 2	Homo sapiens		 18.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688808	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688808&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430048	504490478							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433624	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)ncc2COC2(C)COC2)C(=O)N1	InChI=1S/C26H25N5O3S/c1-4-20-27-10-15(11-34-26(3)12-33-13-26)22(31-20)18-6-5-16-17(30-18)7-8-19-21(16)23-24(35-19)25(32)29-14(2)9-28-23/h4-8,10,14,28H,1,9,11-13H2,2-3H3,(H,29,32)/t14-/m1/s1	LEQJYFUUAIXVFI-CQSZACIVSA-N	688809	(R)-10-methyl-3-(5-(((3-methyloxetan-3-yl)oxy)methyl)-2-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-29	MAP kinase-activated protein kinase 2	Homo sapiens		 20.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688809	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688809&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430049	504490479							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433625	CCOCc1nc(Cl)cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H20ClN5O2S/c1-3-30-10-18-27-15(8-17(23)28-18)14-5-4-12-13(26-14)6-7-16-19(12)20-21(31-16)22(29)25-11(2)9-24-20/h4-8,11,24H,3,9-10H2,1-2H3,(H,25,29)/t11-/m1/s1	DDYIJJDQUHFVDK-LLVKDONJSA-N	688810	(R)-3-(6-chloro-2-(ethoxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-30	MAP kinase-activated protein kinase 2	Homo sapiens		 16.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688810	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688810&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430050	504490480							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433626	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(ncc2F)C(F)=C)C(=O)N1	InChI=1S/C21H15F2N5OS/c1-9-7-24-18-16-11-3-4-14(17-12(23)8-25-20(28-17)10(2)22)27-13(11)5-6-15(16)30-19(18)21(29)26-9/h3-6,8-9,24H,2,7H2,1H3,(H,26,29)/t9-/m1/s1	AIORCMBYICBIPW-SECBINFHSA-N	688811	(R)-3-(5-fluoro-2-(1-fluorovinyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-31	MAP kinase-activated protein kinase 2	Homo sapiens		 24.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688811	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688811&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542372	504490481							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433627	COc1cnc(C=C)nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H19N5O2S/c1-4-17-23-10-15(29-3)19(27-17)14-6-5-12-13(26-14)7-8-16-18(12)20-21(30-16)22(28)25-11(2)9-24-20/h4-8,10-11,24H,1,9H2,2-3H3,(H,25,28)/t11-/m1/s1	ZSNFZBZFZAUJRD-LLVKDONJSA-N	688812	(R)-3-(5-methoxy-2-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-32	MAP kinase-activated protein kinase 2	Homo sapiens		 245							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688812	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688812&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541942	504490482							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433628	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)ncc2C)C(=O)N1	InChI=1S/C22H19N5OS/c1-4-17-23-9-11(2)19(27-17)15-6-5-13-14(26-15)7-8-16-18(13)20-21(29-16)22(28)25-12(3)10-24-20/h4-9,12,24H,1,10H2,2-3H3,(H,25,28)/t12-/m1/s1	RAWKURMVCZTJOF-GFCCVEGCSA-N	688813	(R)-10-methyl-3-(5-methyl-2-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-33	MAP kinase-activated protein kinase 2	Homo sapiens		 120							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688813	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688813&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542187	504490483							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433629	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncn2)C(=O)N1	InChI=1S/C21H17N5OS/c1-3-12-8-16(24-10-23-12)15-5-4-13-14(26-15)6-7-17-18(13)19-20(28-17)21(27)25-11(2)9-22-19/h3-8,10-11,22H,1,9H2,2H3,(H,25,27)/t11-/m1/s1	JOGRWPGDQIWXTF-LLVKDONJSA-N	688814	(R)-10-methyl-3-(6-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-34	MAP kinase-activated protein kinase 2	Homo sapiens		 13.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688814	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688814&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542249	504490484							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433630	CCOCc1nc(\C=C\C)cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H25N5O2S/c1-4-6-15-11-19(30-21(28-15)13-32-5-2)18-8-7-16-17(29-18)9-10-20-22(16)23-24(33-20)25(31)27-14(3)12-26-23/h4,6-11,14,26H,5,12-13H2,1-3H3,(H,27,31)/b6-4+/t14-/m1/s1	YVIHCSPDXLEDAA-YVARQFDVSA-N	688815	(R,E)-3-(2-(ethoxymethyl)-6-(prop-1-en-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-35	MAP kinase-activated protein kinase 2	Homo sapiens		 40.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688815	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688815&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430051	504490485							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433631	CCOCc1nc(\C=C/C)cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H25N5O2S/c1-4-6-15-11-19(30-21(28-15)13-32-5-2)18-8-7-16-17(29-18)9-10-20-22(16)23-24(33-20)25(31)27-14(3)12-26-23/h4,6-11,14,26H,5,12-13H2,1-3H3,(H,27,31)/b6-4-/t14-/m1/s1	YVIHCSPDXLEDAA-KXQLTZBTSA-N	688816	(R,Z)-3-(2-(ethoxymethyl)-6-(prop-1-en-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-36	MAP kinase-activated protein kinase 2	Homo sapiens		 12.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688816	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688816&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430052	504490486							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433632	CCOCc1nc(cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C(C)=C	InChI=1S/C25H25N5O2S/c1-5-32-12-21-29-18(13(2)3)10-19(30-21)17-7-6-15-16(28-17)8-9-20-22(15)23-24(33-20)25(31)27-14(4)11-26-23/h6-10,14,26H,2,5,11-12H2,1,3-4H3,(H,27,31)/t14-/m1/s1	BIVOXTKEWOGODP-CQSZACIVSA-N	688817	(R)-3-(2-(ethoxymethyl)-6-(prop-1-en-2-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-37	MAP kinase-activated protein kinase 2	Homo sapiens		 10.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688817	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688817&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430053	504490487							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433633	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncn2)C#C)C(=O)N1	InChI=1S/C21H15N5OS/c1-3-12-8-16(24-10-23-12)15-5-4-13-14(26-15)6-7-17-18(13)19-20(28-17)21(27)25-11(2)9-22-19/h1,4-8,10-11,22H,9H2,2H3,(H,25,27)/t11-/m1/s1	KICRPFCNWPLNPV-LLVKDONJSA-N	688818	(R)-3-(6-ethynylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-38	MAP kinase-activated protein kinase 2	Homo sapiens		 5.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688818	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688818&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542115	504490488							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433634	CCOCc1nc(cc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C#C	InChI=1S/C24H21N5O2S/c1-4-14-10-18(29-20(27-14)12-31-5-2)17-7-6-15-16(28-17)8-9-19-21(15)22-23(32-19)24(30)26-13(3)11-25-22/h1,6-10,13,25H,5,11-12H2,2-3H3,(H,26,30)/t13-/m1/s1	MPFLTQYLTCEPKM-CYBMUJFWSA-N	688819	(R)-3-(2-(ethoxymethyl)-6-ethynylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-39	MAP kinase-activated protein kinase 2	Homo sapiens		 8.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688819	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688819&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430054	504490489							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433635	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(n2)C#C)C(=O)N1	InChI=1S/C21H15N5OS/c1-3-17-22-9-8-15(26-17)14-5-4-12-13(25-14)6-7-16-18(12)19-20(28-16)21(27)24-11(2)10-23-19/h1,4-9,11,23H,10H2,2H3,(H,24,27)/t11-/m1/s1	XUNBSQBNWUKIOH-LLVKDONJSA-N	688820	(R)-3-(2-ethynylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-40	MAP kinase-activated protein kinase 2	Homo sapiens		 25.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688820	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688820&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542221	504490490							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433636	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(ncc2C)C#C)C(=O)N1	InChI=1S/C22H17N5OS/c1-4-17-23-9-11(2)19(27-17)15-6-5-13-14(26-15)7-8-16-18(13)20-21(29-16)22(28)25-12(3)10-24-20/h1,5-9,12,24H,10H2,2-3H3,(H,25,28)/t12-/m1/s1	XRYIJBLDIZNAOU-GFCCVEGCSA-N	688821	(R)-3-(2-ethynyl-5-methylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-41	MAP kinase-activated protein kinase 2	Homo sapiens		 199							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688821	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688821&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541919	504490491							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433637	COc1cnc(nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C#C	InChI=1S/C22H17N5O2S/c1-4-17-23-10-15(29-3)19(27-17)14-6-5-12-13(26-14)7-8-16-18(12)20-21(30-16)22(28)25-11(2)9-24-20/h1,5-8,10-11,24H,9H2,2-3H3,(H,25,28)/t11-/m1/s1	XFQSIHBBSVWUHX-LLVKDONJSA-N	688822	(R)-3-(2-ethynyl-5-methoxypyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-42	MAP kinase-activated protein kinase 2	Homo sapiens		 233							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688822	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688822&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542104	504490492							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433638	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)cc(n2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C24H24ClN7OS/c1-13-12-26-21-20-14-3-4-16(28-15(14)5-6-17(20)34-22(21)24(33)27-13)23-29-18(25)11-19(30-23)32-9-7-31(2)8-10-32/h3-6,11,13,26H,7-10,12H2,1-2H3,(H,27,33)/t13-/m1/s1	BWNDEJUMHXPHMS-CYBMUJFWSA-N	688823	(R)-3-(4-chloro-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-43	MAP kinase-activated protein kinase 2	Homo sapiens		 440							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688823	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688823&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541996	504490493							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433639	CC#Cc1ncc(F)c(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H16FN5OS/c1-3-4-17-24-10-13(23)19(28-17)15-6-5-12-14(27-15)7-8-16-18(12)20-21(30-16)22(29)26-11(2)9-25-20/h5-8,10-11,25H,9H2,1-2H3,(H,26,29)/t11-/m1/s1	XLHGCCPGQZNFQM-LLVKDONJSA-N	688824	(R)-3-(5-fluoro-2-(prop-1-yn-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-44	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688824	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688824&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430055	504490494							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433640	C\C=C\c1ncc(F)c(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H18FN5OS/c1-3-4-17-24-10-13(23)19(28-17)15-6-5-12-14(27-15)7-8-16-18(12)20-21(30-16)22(29)26-11(2)9-25-20/h3-8,10-11,25H,9H2,1-2H3,(H,26,29)/b4-3+/t11-/m1/s1	FLNIFDUJLFXYGW-PGLGOXFNSA-N	688825	(R,E)-3-(5-fluoro-2-(prop-1-en-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-45	MAP kinase-activated protein kinase 2	Homo sapiens		 160							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688825	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688825&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430056	504490495							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433641	C\C=C/c1ncc(F)c(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H18FN5OS/c1-3-4-17-24-10-13(23)19(28-17)15-6-5-12-14(27-15)7-8-16-18(12)20-21(30-16)22(29)26-11(2)9-25-20/h3-8,10-11,25H,9H2,1-2H3,(H,26,29)/b4-3-/t11-/m1/s1	FLNIFDUJLFXYGW-DLRQAJBASA-N	688826	(R,Z)-3-(5-fluoro-2-(prop-1-en-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-46	MAP kinase-activated protein kinase 2	Homo sapiens		 765							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688826	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688826&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430057	504490496							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433642	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(ncc2F)C(C)=C)C(=O)N1	InChI=1S/C22H18FN5OS/c1-10(2)21-25-9-13(23)18(28-21)15-5-4-12-14(27-15)6-7-16-17(12)19-20(30-16)22(29)26-11(3)8-24-19/h4-7,9,11,24H,1,8H2,2-3H3,(H,26,29)/t11-/m1/s1	VHRFDKQHROTPCY-LLVKDONJSA-N	688827	(R)-3-(5-fluoro-2-(prop-1-en-2-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-47	MAP kinase-activated protein kinase 2	Homo sapiens		 429							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688827	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688827&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430058	504490497							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433643	CCOCc1cnc(\C=C\C)nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H25N5O2S/c1-4-6-20-26-12-15(13-32-5-2)22(30-20)18-8-7-16-17(29-18)9-10-19-21(16)23-24(33-19)25(31)28-14(3)11-27-23/h4,6-10,12,14,27H,5,11,13H2,1-3H3,(H,28,31)/b6-4+/t14-/m1/s1	DQBHCTFMVKFFLY-YVARQFDVSA-N	688828	(R,E)-3-(5-(ethoxymethyl)-2-(prop-1-en-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-48	MAP kinase-activated protein kinase 2	Homo sapiens		 371							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688828	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688828&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430059	504490498							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433644	CCOCc1cnc(\C=C/C)nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H25N5O2S/c1-4-6-20-26-12-15(13-32-5-2)22(30-20)18-8-7-16-17(29-18)9-10-19-21(16)23-24(33-19)25(31)28-14(3)11-27-23/h4,6-10,12,14,27H,5,11,13H2,1-3H3,(H,28,31)/b6-4-/t14-/m1/s1	DQBHCTFMVKFFLY-KXQLTZBTSA-N	688829	(R,Z)-3-(5-(ethoxymethyl)-2-(prop-1-en-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-49	MAP kinase-activated protein kinase 2	Homo sapiens		 474							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688829	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688829&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430060	504490499							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433645	CCOCc1cnc(nc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C(C)=C	InChI=1S/C25H25N5O2S/c1-5-32-12-15-11-27-24(13(2)3)30-21(15)18-7-6-16-17(29-18)8-9-19-20(16)22-23(33-19)25(31)28-14(4)10-26-22/h6-9,11,14,26H,2,5,10,12H2,1,3-4H3,(H,28,31)/t14-/m1/s1	MVGUVPJNHMGYPJ-CQSZACIVSA-N	688830	(R)-3-(5-(ethoxymethyl)-2-(prop-1-en-2-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-50	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688830	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688830&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430061	504490500							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433646	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnnc(c2)C#C)C(=O)N1	InChI=1S/C21H15N5OS/c1-3-13-8-12(10-23-26-13)15-5-4-14-16(25-15)6-7-17-18(14)19-20(28-17)21(27)24-11(2)9-22-19/h1,4-8,10-11,22H,9H2,2H3,(H,24,27)/t11-/m1/s1	BVBXVSHVIMXLMZ-LLVKDONJSA-N	688831	(R)-3-(6-ethynylpyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-51	MAP kinase-activated protein kinase 2	Homo sapiens		 3.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688831	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688831&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541965	504490501							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433647	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cccc(Cl)n2)C(=O)N1	InChI=1S/C20H15ClN4OS/c1-10-9-22-18-17-11-5-6-14(13-3-2-4-16(21)25-13)24-12(11)7-8-15(17)27-19(18)20(26)23-10/h2-8,10,22H,9H2,1H3,(H,23,26)/t10-/m1/s1	USFZWJWCDFAMEY-SNVBAGLBSA-N	688832	(R)-3-(6-chloropyridin-2-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-52	MAP kinase-activated protein kinase 2	Homo sapiens		 116							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688832	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688832&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542211	504490502							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433648	CC#Cc1nccc(n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H17N5OS/c1-3-4-18-23-10-9-16(27-18)15-6-5-13-14(26-15)7-8-17-19(13)20-21(29-17)22(28)25-12(2)11-24-20/h5-10,12,24H,11H2,1-2H3,(H,25,28)/t12-/m1/s1	NUQBINNJLBLWCE-GFCCVEGCSA-N	688833	(R)-10-methyl-3-(2-(prop-1-yn-1-yl)pyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-53	MAP kinase-activated protein kinase 2	Homo sapiens		 213							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688833	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688833&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542063	504490503							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433649	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cccc(C=C)n2)C(=O)N1	InChI=1S/C22H18N4OS/c1-3-13-5-4-6-16(25-13)17-8-7-14-15(26-17)9-10-18-19(14)20-21(28-18)22(27)24-12(2)11-23-20/h3-10,12,23H,1,11H2,2H3,(H,24,27)/t12-/m1/s1	OHCFGXSCVPFNGX-GFCCVEGCSA-N	688834	(R)-10-methyl-3-(6-vinylpyridin-2-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-54	MAP kinase-activated protein kinase 2	Homo sapiens		 61.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688834	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688834&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541935	504490504							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433650	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(C=C)c2)C(=O)N1	InChI=1S/C22H18N4OS/c1-3-14-10-13(8-9-23-14)16-5-4-15-17(26-16)6-7-18-19(15)20-21(28-18)22(27)25-12(2)11-24-20/h3-10,12,24H,1,11H2,2H3,(H,25,27)/t12-/m1/s1	MYNYYKUDCHZRNE-GFCCVEGCSA-N	688835	(R)-10-methyl-3-(2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-55	MAP kinase-activated protein kinase 2	Homo sapiens		 1.000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688835	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688835&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542200	504490505							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433651	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cccc(n2)C#C)C(=O)N1	InChI=1S/C22H16N4OS/c1-3-13-5-4-6-16(25-13)17-8-7-14-15(26-17)9-10-18-19(14)20-21(28-18)22(27)24-12(2)11-23-20/h1,4-10,12,23H,11H2,2H3,(H,24,27)/t12-/m1/s1	PNBFNBZSDRFBDS-GFCCVEGCSA-N	688836	(R)-3-(6-ethynylpyridin-2-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-56	MAP kinase-activated protein kinase 2	Homo sapiens		 194							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688836	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688836&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542041	504490506							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433652	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(c2)C#C)C(=O)N1	InChI=1S/C22H16N4OS/c1-3-14-10-13(8-9-23-14)16-5-4-15-17(26-16)6-7-18-19(15)20-21(28-18)22(27)25-12(2)11-24-20/h1,4-10,12,24H,11H2,2H3,(H,25,27)/t12-/m1/s1	JWDHKFRHTPOZEQ-GFCCVEGCSA-N	688837	(R)-3-(2-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-57	MAP kinase-activated protein kinase 2	Homo sapiens		 117							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688837	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688837&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542335	504490507							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433653	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(Cl)n2)C(=O)N1	InChI=1S/C19H13Cl2N5OS/c1-8-7-22-16-15-9-2-3-11(12-6-14(20)26-19(21)25-12)24-10(9)4-5-13(15)28-17(16)18(27)23-8/h2-6,8,22H,7H2,1H3,(H,23,27)/t8-/m1/s1	MKWSHKGKZOOOJG-MRVPVSSYSA-N	688838	(R)-3-(2,6-dichloropyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-58	MAP kinase-activated protein kinase 2	Homo sapiens		 16.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688838	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688838&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542089	504490508							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433654	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(n2)N2CCN(C)CC2)C#C)C(=O)N1	InChI=1S/C26H25N7OS/c1-4-16-13-20(31-26(29-16)33-11-9-32(3)10-12-33)19-6-5-17-18(30-19)7-8-21-22(17)23-24(35-21)25(34)28-15(2)14-27-23/h1,5-8,13,15,27H,9-12,14H2,2-3H3,(H,28,34)/t15-/m1/s1	KQFCYNIFDYXONJ-OAHLLOKOSA-N	688839	(R)-3-(6-ethynyl-2-(4-methylpiperazin-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-59	MAP kinase-activated protein kinase 2	Homo sapiens		 3.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688839	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688839&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541894	504490509							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433655	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(n2)C#C)N2CCN(C)CC2)C(=O)N1	InChI=1S/C26H25N7OS/c1-4-21-30-19(13-22(31-21)33-11-9-32(3)10-12-33)18-6-5-16-17(29-18)7-8-20-23(16)24-25(35-20)26(34)28-15(2)14-27-24/h1,5-8,13,15,27H,9-12,14H2,2-3H3,(H,28,34)/t15-/m1/s1	SMBZDMXJIVBQRD-OAHLLOKOSA-N	688840	(R)-3-(2-ethynyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-60	MAP kinase-activated protein kinase 2	Homo sapiens		 58.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688840	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688840&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542367	504490510							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433656	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(cc(n2)N2CCN(C)CC2)C#C)C(=O)N1	InChI=1S/C26H25N7OS/c1-4-16-13-21(33-11-9-32(3)10-12-33)31-25(29-16)19-6-5-17-18(30-19)7-8-20-22(17)23-24(35-20)26(34)28-15(2)14-27-23/h1,5-8,13,15,27H,9-12,14H2,2-3H3,(H,28,34)/t15-/m1/s1	SDTWKSUZEDOUTH-OAHLLOKOSA-N	688841	(R)-3-(4-ethynyl-6-(4-methylpiperazin-1-yl)pyrimidin-2-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-61	MAP kinase-activated protein kinase 2	Homo sapiens		 73.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688841	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688841&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541981	504490511							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433657	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)cc(n2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C26H27N7OS/c1-4-16-13-21(33-11-9-32(3)10-12-33)31-25(29-16)19-6-5-17-18(30-19)7-8-20-22(17)23-24(35-20)26(34)28-15(2)14-27-23/h4-8,13,15,27H,1,9-12,14H2,2-3H3,(H,28,34)/t15-/m1/s1	KJIOXAVMHVNNKF-OAHLLOKOSA-N	688842	(R)-10-methyl-3-(4-(4-methylpiperazin-1-yl)-6-vinylpyrimidin-2-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-62	MAP kinase-activated protein kinase 2	Homo sapiens		 27.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688842	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688842&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541921	504490512							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433658	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(Cl)n2)C#CC(C)(C)N)C(=O)N1	InChI=1S/C24H21ClN6OS/c1-12-11-27-20-19-14-4-5-16(17-10-13(29-23(25)31-17)8-9-24(2,3)26)30-15(14)6-7-18(19)33-21(20)22(32)28-12/h4-7,10,12,27H,11,26H2,1-3H3,(H,28,32)/t12-/m1/s1	FSRYAVYJLZEZID-GFCCVEGCSA-N	688843	(R)-3-(6-(3-amino-3-methylbut-1-yn-1-yl)-2-chloropyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-63	MAP kinase-activated protein kinase 2	Homo sapiens		 145							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688843	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688843&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542380	504490513							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433659	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(n2)C#CC(C)(C)N)C(=O)N1	InChI=1S/C24H21ClN6OS/c1-12-11-27-21-20-13-4-5-15(16-10-18(25)31-19(30-16)8-9-24(2,3)26)29-14(13)6-7-17(20)33-22(21)23(32)28-12/h4-7,10,12,27H,11,26H2,1-3H3,(H,28,32)/t12-/m1/s1	YETBMUOJAIZBLY-GFCCVEGCSA-N	688844	(R)-3-(2-(3-amino-3-methylbut-1-yn-1-yl)-6-chloropyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-64	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688844	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688844&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541889	504490514							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433660	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(n2)C#C)C#CC(C)(C)N)C(=O)N1	InChI=1S/C26H22N6OS/c1-5-21-30-15(10-11-26(3,4)27)12-19(32-21)18-7-6-16-17(31-18)8-9-20-22(16)23-24(34-20)25(33)29-14(2)13-28-23/h1,6-9,12,14,28H,13,27H2,2-4H3,(H,29,33)/t14-/m1/s1	XFEZDBSDHKHXRV-CQSZACIVSA-N	688845	(R)-3-(6-(3-amino-3-methylbut-1-yn-1-yl)-2-ethynylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-65	MAP kinase-activated protein kinase 2	Homo sapiens		 132							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688845	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688845&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542057	504490515							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433661	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(n2)C#CC(C)(C)N)C(=O)N1	InChI=1S/C26H24N6OS/c1-5-15-12-19(32-21(30-15)10-11-26(3,4)27)18-7-6-16-17(31-18)8-9-20-22(16)23-24(34-20)25(33)29-14(2)13-28-23/h5-9,12,14,28H,1,13,27H2,2-4H3,(H,29,33)/t14-/m1/s1	HBSWQVAYBXTFRM-CQSZACIVSA-N	688846	(R)-3-(2-(3-amino-3-methylbut-1-yn-1-yl)-6-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-66	MAP kinase-activated protein kinase 2	Homo sapiens		 9.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688846	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688846&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542356	504490516							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433662	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(n2)C#CC(C)(C)N)C#C)C(=O)N1	InChI=1S/C26H22N6OS/c1-5-15-12-19(32-21(30-15)10-11-26(3,4)27)18-7-6-16-17(31-18)8-9-20-22(16)23-24(34-20)25(33)29-14(2)13-28-23/h1,6-9,12,14,28H,13,27H2,2-4H3,(H,29,33)/t14-/m1/s1	FACXTMRYVBCUSA-CQSZACIVSA-N	688847	(R)-3-(2-(3-amino-3-methylbut-1-yn-1-yl)-6-ethynylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-67	MAP kinase-activated protein kinase 2	Homo sapiens		 38.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688847	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688847&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542090	504490517							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433663	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(Cl)c2)C(=O)N1	InChI=1S/C20H14Cl2N4OS/c1-9-8-23-18-17-11-2-3-12(10-6-15(21)26-16(22)7-10)25-13(11)4-5-14(17)28-19(18)20(27)24-9/h2-7,9,23H,8H2,1H3,(H,24,27)/t9-/m1/s1	OMVLFGQFIWVUHE-SECBINFHSA-N	688848	(R)-3-(2,6-dichloropyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-68	MAP kinase-activated protein kinase 2	Homo sapiens		 472							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688848	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688848&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541904	504490518							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433664	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)ncc2F)C(=O)N1	InChI=1S/C20H14ClFN4OS/c1-9-7-24-18-17-10-2-3-14(11-6-16(21)23-8-12(11)22)26-13(10)4-5-15(17)28-19(18)20(27)25-9/h2-6,8-9,24H,7H2,1H3,(H,25,27)/t9-/m1/s1	QNARWVANLCWUGN-SECBINFHSA-N	688849	(R)-3-(2-chloro-5-fluoropyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-69	MAP kinase-activated protein kinase 2	Homo sapiens		 27.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688849	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688849&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541917	504490519							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433665	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2F)C(=O)N1	InChI=1S/C22H17FN4OS/c1-3-12-8-14(15(23)10-24-12)17-5-4-13-16(27-17)6-7-18-19(13)20-21(29-18)22(28)26-11(2)9-25-20/h3-8,10-11,25H,1,9H2,2H3,(H,26,28)/t11-/m1/s1	XYOHFBMGNDCRQP-LLVKDONJSA-N	688850	(R)-3-(5-fluoro-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-70	MAP kinase-activated protein kinase 2	Homo sapiens		 64.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688850&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542081	504490520							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433666	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2F)C(=O)N1	InChI=1S/C22H17FN4OS/c1-3-12-8-14(15(23)10-24-12)17-5-4-13-16(27-17)6-7-18-19(13)20-21(29-18)22(28)26-11(2)9-25-20/h3-8,10-11,25H,1,9H2,2H3,(H,26,28)/t11-/m1/s1	XYOHFBMGNDCRQP-LLVKDONJSA-N	688850	(R)-3-(5-fluoro-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-70	MAP kinase-activated protein kinase 2	Homo sapiens		 64.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688850	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688850&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542081	504490520							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433667	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncc2F)C#C)C(=O)N1	InChI=1S/C22H15FN4OS/c1-3-12-8-14(15(23)10-24-12)17-5-4-13-16(27-17)6-7-18-19(13)20-21(29-18)22(28)26-11(2)9-25-20/h1,4-8,10-11,25H,9H2,2H3,(H,26,28)/t11-/m1/s1	WKWBAHVAISIMRG-LLVKDONJSA-N	688851	(R)-3-(2-ethynyl-5-fluoropyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-71	MAP kinase-activated protein kinase 2	Homo sapiens		 39.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688851	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688851&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542265	504490521							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433668	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(C=C)c2)C(=O)N1	InChI=1S/C22H17ClN4OS/c1-3-13-8-12(9-18(23)26-13)15-5-4-14-16(27-15)6-7-17-19(14)20-21(29-17)22(28)25-11(2)10-24-20/h3-9,11,24H,1,10H2,2H3,(H,25,28)/t11-/m1/s1	IPMSWOLKTYVOQD-LLVKDONJSA-N	688852	(R)-3-(2-chloro-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-72	MAP kinase-activated protein kinase 2	Homo sapiens		 58.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688852	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688852&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541913	504490522							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433669	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(c2)C#C)C(=O)N1	InChI=1S/C22H15ClN4OS/c1-3-13-8-12(9-18(23)26-13)15-5-4-14-16(27-15)6-7-17-19(14)20-21(29-17)22(28)25-11(2)10-24-20/h1,4-9,11,24H,10H2,2H3,(H,25,28)/t11-/m1/s1	KNWZKFSMKARMPX-LLVKDONJSA-N	688853	(R)-3-(2-chloro-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-73	MAP kinase-activated protein kinase 2	Homo sapiens		 75.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688853	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688853&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542182	504490523							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433670	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(CO)n2)C(=O)N1	InChI=1S/C20H16ClN5O2S/c1-9-7-22-18-17-10-2-3-12(13-6-15(21)26-16(8-27)25-13)24-11(10)4-5-14(17)29-19(18)20(28)23-9/h2-6,9,22,27H,7-8H2,1H3,(H,23,28)/t9-/m1/s1	YYCUVRNNEYIWTL-SECBINFHSA-N	688854	(R)-3-(6-chloro-2-(hydroxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-74	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688854	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688854&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542395	504490524							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433671	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2CO)C(=O)N1	InChI=1S/C20H16ClN5O2S/c1-9-6-22-17-15-11-2-3-13(16-10(8-27)7-23-20(21)26-16)25-12(11)4-5-14(15)29-18(17)19(28)24-9/h2-5,7,9,22,27H,6,8H2,1H3,(H,24,28)/t9-/m1/s1	MQLHTPGAZSKJLV-SECBINFHSA-N	688855	(R)-3-(2-chloro-5-(hydroxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-75	MAP kinase-activated protein kinase 2	Homo sapiens		 470							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688855	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688855&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430062	504490525							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433672	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(CO)n2)C(=O)N1	InChI=1S/C22H19N5O2S/c1-3-12-8-16(27-18(10-28)25-12)15-5-4-13-14(26-15)6-7-17-19(13)20-21(30-17)22(29)24-11(2)9-23-20/h3-8,11,23,28H,1,9-10H2,2H3,(H,24,29)/t11-/m1/s1	XMULTJFUTVJKSI-LLVKDONJSA-N	688856	(R)-3-(2-(hydroxymethyl)-6-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-76	MAP kinase-activated protein kinase 2	Homo sapiens		 1.000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688856	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688856&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171723350	504490526							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433673	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)ncc2CO)C(=O)N1	InChI=1S/C22H19N5O2S/c1-3-17-23-9-12(10-28)19(27-17)15-5-4-13-14(26-15)6-7-16-18(13)20-21(30-16)22(29)25-11(2)8-24-20/h3-7,9,11,24,28H,1,8,10H2,2H3,(H,25,29)/t11-/m1/s1	OVNZURBXUWSRNU-LLVKDONJSA-N	688857	(R)-3-(5-(hydroxymethyl)-2-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-77	MAP kinase-activated protein kinase 2	Homo sapiens		 13.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688857	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688857&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430063	504490527							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433674	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(CO)n2)C#C)C(=O)N1	InChI=1S/C22H17N5O2S/c1-3-12-8-16(27-18(10-28)25-12)15-5-4-13-14(26-15)6-7-17-19(13)20-21(30-17)22(29)24-11(2)9-23-20/h1,4-8,11,23,28H,9-10H2,2H3,(H,24,29)/t11-/m1/s1	KWAQTRMBRFUMSW-LLVKDONJSA-N	688858	(R)-3-(6-ethynyl-2-(hydroxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-78	MAP kinase-activated protein kinase 2	Homo sapiens		 1.000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688858	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688858&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430064	504490528							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433675	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(ncc2CO)C#C)C(=O)N1	InChI=1S/C22H17N5O2S/c1-3-17-23-9-12(10-28)19(27-17)15-5-4-13-14(26-15)6-7-16-18(13)20-21(30-16)22(29)25-11(2)8-24-20/h1,4-7,9,11,24,28H,8,10H2,2H3,(H,25,29)/t11-/m1/s1	OMUCUAHETUELSO-LLVKDONJSA-N	688859	(R)-3-(2-ethynyl-5-(hydroxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-79	MAP kinase-activated protein kinase 2	Homo sapiens		 568							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688859	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688859&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430065	504490529							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433676	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(C=C)c2)C(=O)N1	InChI=1S/C24H20N4OS/c1-4-15-10-14(11-16(5-2)27-15)18-7-6-17-19(28-18)8-9-20-21(17)22-23(30-20)24(29)26-13(3)12-25-22/h4-11,13,25H,1-2,12H2,3H3,(H,26,29)/t13-/m1/s1	LADNKUIQYTXGLE-CYBMUJFWSA-N	688860	(R)-3-(2,6-divinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-80	MAP kinase-activated protein kinase 2	Homo sapiens		 574							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688860	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688860&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542258	504490530							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433677	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cncc(Cl)c2)C(=O)N1	InChI=1S/C20H15ClN4OS/c1-10-7-23-18-17-13-2-3-14(11-6-12(21)9-22-8-11)25-15(13)4-5-16(17)27-19(18)20(26)24-10/h2-6,8-10,23H,7H2,1H3,(H,24,26)/t10-/m1/s1	QQTGTJWFPXQYGI-SNVBAGLBSA-N	688861	(R)-3-(5-chloropyridin-3-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-81	MAP kinase-activated protein kinase 2	Homo sapiens		 90.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688861	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688861&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542185	504490531							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433678	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cncc(C=C)c2)C(=O)N1	InChI=1S/C22H18N4OS/c1-3-13-8-14(11-23-10-13)16-5-4-15-17(26-16)6-7-18-19(15)20-21(28-18)22(27)25-12(2)9-24-20/h3-8,10-12,24H,1,9H2,2H3,(H,25,27)/t12-/m1/s1	KOEVHPWTIDKAJL-GFCCVEGCSA-N	688862	(R)-10-methyl-3-(5-vinylpyridin-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-82	MAP kinase-activated protein kinase 2	Homo sapiens		 21.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688862	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688862&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542075	504490532							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433679	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cncc(c2)C#C)C(=O)N1	InChI=1S/C22H16N4OS/c1-3-13-8-14(11-23-10-13)16-5-4-15-17(26-16)6-7-18-19(15)20-21(28-18)22(27)25-12(2)9-24-20/h1,4-8,10-12,24H,9H2,2H3,(H,25,27)/t12-/m1/s1	GUHDAQXDOKYXAR-GFCCVEGCSA-N	688863	(R)-3-(5-ethynylpyridin-3-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-83	MAP kinase-activated protein kinase 2	Homo sapiens		 83.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688863	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688863&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542389	504490533							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433680	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CO)nc(Cl)n2)C(=O)N1	InChI=1S/C20H16ClN5O2S/c1-9-7-22-17-16-11-2-3-13(14-6-10(8-27)24-20(21)26-14)25-12(11)4-5-15(16)29-18(17)19(28)23-9/h2-6,9,22,27H,7-8H2,1H3,(H,23,28)/t9-/m1/s1	VYWUDUXGQOKZTP-SECBINFHSA-N	688864	(R)-3-(2-chloro-6-(hydroxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-84	MAP kinase-activated protein kinase 2	Homo sapiens		 39.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688864	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688864&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430066	504490534							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433681	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CO)nc(C=C)n2)C(=O)N1	InChI=1S/C22H19N5O2S/c1-3-18-25-12(10-28)8-16(27-18)15-5-4-13-14(26-15)6-7-17-19(13)20-21(30-17)22(29)24-11(2)9-23-20/h3-8,11,23,28H,1,9-10H2,2H3,(H,24,29)/t11-/m1/s1	CILBQUCMCQOTOD-LLVKDONJSA-N	688865	(R)-3-(6-(hydroxymethyl)-2-vinylpyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-85	MAP kinase-activated protein kinase 2	Homo sapiens		 11.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688865	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688865&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430067	504490535							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433682	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CO)nc(n2)C#C)C(=O)N1	InChI=1S/C22H17N5O2S/c1-3-18-25-12(10-28)8-16(27-18)15-5-4-13-14(26-15)6-7-17-19(13)20-21(30-17)22(29)24-11(2)9-23-20/h1,4-8,11,23,28H,9-10H2,2H3,(H,24,29)/t11-/m1/s1	SJCFLQQWVNXDRI-LLVKDONJSA-N	688866	(R)-3-(2-ethynyl-6-(hydroxymethyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-86	MAP kinase-activated protein kinase 2	Homo sapiens		 23.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688866	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688866&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430068	504490536							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433683	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCN(C)CC3)nc(Cl)n2)C(=O)N1	InChI=1S/C25H26ClN7OS/c1-14-12-27-22-21-16-3-4-18(30-17(16)5-6-20(21)35-23(22)24(34)28-14)19-11-15(29-25(26)31-19)13-33-9-7-32(2)8-10-33/h3-6,11,14,27H,7-10,12-13H2,1-2H3,(H,28,34)/t14-/m1/s1	URGLCIMOWPVOLD-CQSZACIVSA-N	688867	(R)-3-(2-chloro-6-((4-methylpiperazin-1-yl)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-87	MAP kinase-activated protein kinase 2	Homo sapiens		 283							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688867	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688867&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430069	504490537							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433684	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCN(C)CC3)nc(C=C)n2)C(=O)N1	InChI=1S/C27H29N7OS/c1-4-23-30-17(15-34-11-9-33(3)10-12-34)13-21(32-23)20-6-5-18-19(31-20)7-8-22-24(18)25-26(36-22)27(35)29-16(2)14-28-25/h4-8,13,16,28H,1,9-12,14-15H2,2-3H3,(H,29,35)/t16-/m1/s1	LLNHFYCXMOSNGM-MRXNPFEDSA-N	688868	(R)-10-methyl-3-(6-((4-methylpiperazin-1-yl)methyl)-2-vinylpyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-88	MAP kinase-activated protein kinase 2	Homo sapiens		 15.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688868	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688868&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430070	504490538							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433685	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCN(C)CC3)nc(n2)C#C)C(=O)N1	InChI=1S/C27H27N7OS/c1-4-23-30-17(15-34-11-9-33(3)10-12-34)13-21(32-23)20-6-5-18-19(31-20)7-8-22-24(18)25-26(36-22)27(35)29-16(2)14-28-25/h1,5-8,13,16,28H,9-12,14-15H2,2-3H3,(H,29,35)/t16-/m1/s1	OFDZFWQOGMCBJZ-MRXNPFEDSA-N	688869	(R)-3-(2-ethynyl-6-((4-methylpiperazin-1-yl)methyl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-89	MAP kinase-activated protein kinase 2	Homo sapiens		 26.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688869	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688869&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430071	504490539							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433686	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cccc(n2)C(F)=C)C(=O)N1	InChI=1S/C22H17FN4OS/c1-11-10-24-20-19-13-6-7-17(16-5-3-4-14(26-16)12(2)23)27-15(13)8-9-18(19)29-21(20)22(28)25-11/h3-9,11,24H,2,10H2,1H3,(H,25,28)/t11-/m1/s1	LPCPFSVKXROAOS-LLVKDONJSA-N	688870	(R)-3-(6-(1-fluorovinyl)pyridin-2-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-90	MAP kinase-activated protein kinase 2	Homo sapiens		 460							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688870	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688870&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542275	504490540							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433687	COc1nnc(cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C#C	InChI=1S/C22H17N5O2S/c1-4-12-9-14(22(29-3)27-26-12)16-6-5-13-15(25-16)7-8-17-18(13)19-20(30-17)21(28)24-11(2)10-23-19/h1,5-9,11,23H,10H2,2-3H3,(H,24,28)/t11-/m1/s1	QXXKEYUJNLDSTI-LLVKDONJSA-N	688871	(R)-3-(6-ethynyl-3-methoxypyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-91	MAP kinase-activated protein kinase 2	Homo sapiens		 26.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688871	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688871&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542206	504490541							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433688	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncc2C(F)F)C#C)C(=O)N1	InChI=1S/C23H16F2N4OS/c1-3-12-8-14(15(10-26-12)22(24)25)17-5-4-13-16(29-17)6-7-18-19(13)20-21(31-18)23(30)28-11(2)9-27-20/h1,4-8,10-11,22,27H,9H2,2H3,(H,28,30)/t11-/m1/s1	FENAYSJQMSOLHM-LLVKDONJSA-N	688872	(R)-3-(5-(difluoromethyl)-2-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-92	MAP kinase-activated protein kinase 2	Homo sapiens		 17.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688872	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688872&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430072	504490542							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433689	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)ncc2C(F)F)C(=O)N1	InChI=1S/C21H15ClF2N4OS/c1-9-7-26-18-17-10-2-3-14(11-6-16(22)25-8-12(11)20(23)24)28-13(10)4-5-15(17)30-19(18)21(29)27-9/h2-6,8-9,20,26H,7H2,1H3,(H,27,29)/t9-/m1/s1	KAIBYPNEQHWCHY-SECBINFHSA-N	688873	(R)-3-(2-chloro-5-(difluoromethyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-93	MAP kinase-activated protein kinase 2	Homo sapiens		 238							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688873	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688873&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541875	504490543							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433690	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(c2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C25H25ClN6OS/c1-14-13-27-23-22-16-3-4-17(29-18(16)5-6-19(22)34-24(23)25(33)28-14)15-11-20(26)30-21(12-15)32-9-7-31(2)8-10-32/h3-6,11-12,14,27H,7-10,13H2,1-2H3,(H,28,33)/t14-/m1/s1	IWNLTHZFPGOMBA-CQSZACIVSA-N	688874	(R)-3-(2-chloro-6-(4-methylpiperazin-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-94	MAP kinase-activated protein kinase 2	Homo sapiens		 43.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688874	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688874&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430073	504490544							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433691	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CCN(C)CC2)C#C)C(=O)N1	InChI=1S/C27H26N6OS/c1-4-18-13-17(14-23(30-18)33-11-9-32(3)10-12-33)20-6-5-19-21(31-20)7-8-22-24(19)25-26(35-22)27(34)29-16(2)15-28-25/h1,5-8,13-14,16,28H,9-12,15H2,2-3H3,(H,29,34)/t16-/m1/s1	WNOGJJHITUPYLM-MRXNPFEDSA-N	688875	(R)-3-(2-ethynyl-6-(4-methylpiperazin-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-172::US20240190890, Compound I-95	MAP kinase-activated protein kinase 2	Homo sapiens		 42.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688875&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430074	504490545							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433692	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C27H28N6OS/c1-4-18-13-17(14-23(30-18)33-11-9-32(3)10-12-33)20-6-5-19-21(31-20)7-8-22-24(19)25-26(35-22)27(34)29-16(2)15-28-25/h4-8,13-14,16,28H,1,9-12,15H2,2-3H3,(H,29,34)/t16-/m1/s1	SKVCMCBKRCIKAY-MRXNPFEDSA-N	688876	(R)-10-methyl-3-(2-(4-methylpiperazin-1-yl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-171::US20240190890, Compound I-96	MAP kinase-activated protein kinase 2	Homo sapiens		 10.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688876&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430075	504490546							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433693	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(CO)c2)C(=O)N1	InChI=1S/C21H17ClN4O2S/c1-10-8-23-19-18-13-2-3-14(11-6-12(9-27)25-17(22)7-11)26-15(13)4-5-16(18)29-20(19)21(28)24-10/h2-7,10,23,27H,8-9H2,1H3,(H,24,28)/t10-/m1/s1	MJBZZBZLRALOFA-SNVBAGLBSA-N	688877	(R)-3-(2-chloro-6-(hydroxymethyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-97	MAP kinase-activated protein kinase 2	Homo sapiens		 60.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688877	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688877&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542383	504490547							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433694	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CO)nc(c2)C#C)C(=O)N1	InChI=1S/C23H18N4O2S/c1-3-14-8-13(9-15(11-28)26-14)17-5-4-16-18(27-17)6-7-19-20(16)21-22(30-19)23(29)25-12(2)10-24-21/h1,4-9,12,24,28H,10-11H2,2H3,(H,25,29)/t12-/m1/s1	UGGVWYDMJINZBG-GFCCVEGCSA-N	688878	(R)-3-(2-ethynyl-6-(hydroxymethyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-98	MAP kinase-activated protein kinase 2	Homo sapiens		 60.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688878	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688878&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430076	504490548							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433695	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CO)nc(C=C)c2)C(=O)N1	InChI=1S/C23H20N4O2S/c1-3-14-8-13(9-15(11-28)26-14)17-5-4-16-18(27-17)6-7-19-20(16)21-22(30-19)23(29)25-12(2)10-24-21/h3-9,12,24,28H,1,10-11H2,2H3,(H,25,29)/t12-/m1/s1	IURQLXGXCBYEKY-GFCCVEGCSA-N	688879	(R)-3-(2-(hydroxymethyl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-99	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688879	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688879&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542207	504490549							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433696	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(c2)C2=CCN(C)CC2)C(=O)N1	InChI=1S/C26H24ClN5OS/c1-14-13-28-24-23-17-3-4-18(30-19(17)5-6-21(23)34-25(24)26(33)29-14)16-11-20(31-22(27)12-16)15-7-9-32(2)10-8-15/h3-7,11-12,14,28H,8-10,13H2,1-2H3,(H,29,33)/t14-/m1/s1	LUPYMWFXGJMBNW-CQSZACIVSA-N	688880	(R)-3-(6-chloro-1'-methyl-1',2',3',6'-tetrahydro-[2,4'-bipyridin]-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-100	MAP kinase-activated protein kinase 2	Homo sapiens		 62.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688880	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688880&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430077	504490550							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433697	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)C2=CCN(C)CC2)C(=O)N1	InChI=1S/C28H27N5OS/c1-4-19-13-18(14-23(31-19)17-9-11-33(3)12-10-17)21-6-5-20-22(32-21)7-8-24-25(20)26-27(35-24)28(34)30-16(2)15-29-26/h4-9,13-14,16,29H,1,10-12,15H2,2-3H3,(H,30,34)/t16-/m1/s1	BVYBHWZLOVCVIV-MRXNPFEDSA-N	688881	(R)-10-methyl-3-(1'-methyl-6-vinyl-1',2',3',6'-tetrahydro-[2,4'-bipyridin]-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-101	MAP kinase-activated protein kinase 2	Homo sapiens		 8.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688881	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688881&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430078	504490551							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433698	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)C2=CCN(C)CC2)C#C)C(=O)N1	InChI=1S/C28H25N5OS/c1-4-19-13-18(14-23(31-19)17-9-11-33(3)12-10-17)21-6-5-20-22(32-21)7-8-24-25(20)26-27(35-24)28(34)30-16(2)15-29-26/h1,5-9,13-14,16,29H,10-12,15H2,2-3H3,(H,30,34)/t16-/m1/s1	OUXBVSIMBIWEJQ-MRXNPFEDSA-N	688882	(R)-3-(6-ethynyl-1'-methyl-1',2',3',6'-tetrahydro-[2,4'-bipyridin]-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-102	MAP kinase-activated protein kinase 2	Homo sapiens		 8.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688882	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688882&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430079	504490552							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433699	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nc(c2)C2CCN(C)CC2)C(=O)N1	InChI=1S/C26H26ClN5OS/c1-14-13-28-24-23-17-3-4-18(30-19(17)5-6-21(23)34-25(24)26(33)29-14)16-11-20(31-22(27)12-16)15-7-9-32(2)10-8-15/h3-6,11-12,14-15,28H,7-10,13H2,1-2H3,(H,29,33)/t14-/m1/s1	BGYNTCGGWNGKAN-CQSZACIVSA-N	688883	(R)-3-(2-chloro-6-(1-methylpiperidin-4-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-103	MAP kinase-activated protein kinase 2	Homo sapiens		 46.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688883	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688883&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430080	504490553							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433700	CNc1nnc(cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C#C	InChI=1S/C22H18N6OS/c1-4-12-9-14(21(23-3)28-27-12)16-6-5-13-15(26-16)7-8-17-18(13)19-20(30-17)22(29)25-11(2)10-24-19/h1,5-9,11,24H,10H2,2-3H3,(H,23,28)(H,25,29)/t11-/m1/s1	UDPCYPFQMQTGMT-LLVKDONJSA-N	688884	(R)-3-(6-ethynyl-3-(methylamino)pyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-104	MAP kinase-activated protein kinase 2	Homo sapiens		 194							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688884	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688884&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430081	504490554							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433701	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nnc2N(C)C)C#C)C(=O)N1	InChI=1S/C23H20N6OS/c1-5-13-10-15(22(28-27-13)29(3)4)17-7-6-14-16(26-17)8-9-18-19(14)20-21(31-18)23(30)25-12(2)11-24-20/h1,6-10,12,24H,11H2,2-4H3,(H,25,30)/t12-/m1/s1	KQZVSHNLQHIBEV-GFCCVEGCSA-N	688885	(R)-3-(3-(dimethylamino)-6-ethynylpyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-105	MAP kinase-activated protein kinase 2	Homo sapiens		 118							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688885	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688885&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430082	504490555							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433702	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)C2CCN(C)CC2)C(=O)N1	InChI=1S/C28H29N5OS/c1-4-19-13-18(14-23(31-19)17-9-11-33(3)12-10-17)21-6-5-20-22(32-21)7-8-24-25(20)26-27(35-24)28(34)30-16(2)15-29-26/h4-8,13-14,16-17,29H,1,9-12,15H2,2-3H3,(H,30,34)/t16-/m1/s1	VORXTDOHSCBTLQ-MRXNPFEDSA-N	688886	(R)-10-methyl-3-(2-(1-methylpiperidin-4-yl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-106	MAP kinase-activated protein kinase 2	Homo sapiens		 8.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688886	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688886&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430083	504490556							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433703	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)C2CCN(C)CC2)C#C)C(=O)N1	InChI=1S/C28H27N5OS/c1-4-19-13-18(14-23(31-19)17-9-11-33(3)12-10-17)21-6-5-20-22(32-21)7-8-24-25(20)26-27(35-24)28(34)30-16(2)15-29-26/h1,5-8,13-14,16-17,29H,9-12,15H2,2-3H3,(H,30,34)/t16-/m1/s1	KPCQIPFDACJZEV-MRXNPFEDSA-N	688887	(R)-3-(2-ethynyl-6-(1-methylpiperidin-4-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-107	MAP kinase-activated protein kinase 2	Homo sapiens		 22.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688887	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688887&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430084	504490557							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433704	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(c2)C(F)=C)C(=O)N1	InChI=1S/C22H17FN4OS/c1-11-10-25-20-19-14-3-4-15(13-7-8-24-17(9-13)12(2)23)27-16(14)5-6-18(19)29-21(20)22(28)26-11/h3-9,11,25H,2,10H2,1H3,(H,26,28)/t11-/m1/s1	WTGTUQRPDSIEJV-LLVKDONJSA-N	688888	(R)-3-(2-(1-fluorovinyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-108	MAP kinase-activated protein kinase 2	Homo sapiens		 122							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688888	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688888&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542284	504490558							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433705	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2C)C(=O)N1	InChI=1S/C23H20N4OS/c1-4-14-9-16(12(2)10-24-14)18-6-5-15-17(27-18)7-8-19-20(15)21-22(29-19)23(28)26-13(3)11-25-21/h4-10,13,25H,1,11H2,2-3H3,(H,26,28)/t13-/m1/s1	UIPAEGAJTRBGJU-CYBMUJFWSA-N	688889	(R)-10-methyl-3-(5-methyl-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-109::US20240190890, Compound I-142::US20240190890, Compound I-249	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541925	504490559							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433706	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C)nc(C=C)c2)C(=O)N1	InChI=1S/C23H20N4OS/c1-4-15-10-14(9-12(2)25-15)17-6-5-16-18(27-17)7-8-19-20(16)21-22(29-19)23(28)26-13(3)11-24-21/h4-10,13,24H,1,11H2,2-3H3,(H,26,28)/t13-/m1/s1	SBMAULXQGBRRSW-CYBMUJFWSA-N	688890	(R)-10-methyl-3-(2-methyl-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-110	MAP kinase-activated protein kinase 2	Homo sapiens		 8.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688890	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688890&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541949	504490560							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433707	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncc2C)C#C)C(=O)N1	InChI=1S/C23H18N4OS/c1-4-14-9-16(12(2)10-24-14)18-6-5-15-17(27-18)7-8-19-20(15)21-22(29-19)23(28)26-13(3)11-25-21/h1,5-10,13,25H,11H2,2-3H3,(H,26,28)/t13-/m1/s1	YAJDXWWVQTVUAE-CYBMUJFWSA-N	688891	(R)-3-(2-ethynyl-5-methylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-111	MAP kinase-activated protein kinase 2	Homo sapiens		 104							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688891	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688891&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542293	504490561							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433708	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C)nc(c2)C#C)C(=O)N1	InChI=1S/C23H18N4OS/c1-4-15-10-14(9-12(2)25-15)17-6-5-16-18(27-17)7-8-19-20(16)21-22(29-19)23(28)26-13(3)11-24-21/h1,5-10,13,24H,11H2,2-3H3,(H,26,28)/t13-/m1/s1	VLFAMVMCKKWWOK-CYBMUJFWSA-N	688892	(R)-3-(2-ethynyl-6-methylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-112	MAP kinase-activated protein kinase 2	Homo sapiens		 152							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688892	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688892&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542305	504490562							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433709	C\C=C\c1cc(ccn1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H20N4OS/c1-3-4-15-11-14(9-10-24-15)17-6-5-16-18(27-17)7-8-19-20(16)21-22(29-19)23(28)26-13(2)12-25-21/h3-11,13,25H,12H2,1-2H3,(H,26,28)/b4-3+/t13-/m1/s1	HQYVARCYMGZQEP-ITDFMYJTSA-N	688893	(R,E)-10-methyl-3-(2-(prop-1-en-1-yl)pyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-113	MAP kinase-activated protein kinase 2	Homo sapiens		 53.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688893	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688893&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542322	504490563							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433710	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(\C=C\CN(C)C)c2)C(=O)N1	InChI=1S/C25H25N5OS/c1-15-14-27-23-22-18-6-7-19(16-10-11-26-17(13-16)5-4-12-30(2)3)29-20(18)8-9-21(22)32-24(23)25(31)28-15/h4-11,13,15,27H,12,14H2,1-3H3,(H,28,31)/b5-4+/t15-/m1/s1	IYECGBXOLJNWAH-MBVDDHJVSA-N	688894	(R,E)-3-(2-(3-(dimethylamino)prop-1-en-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-114	MAP kinase-activated protein kinase 2	Homo sapiens		 11.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688894	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688894&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430085	504490564							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433711	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(\C=C\CN(C)C)ncn2)C(=O)N1	InChI=1S/C24H24N6OS/c1-14-12-25-22-21-16-6-7-18(19-11-15(26-13-27-19)5-4-10-30(2)3)29-17(16)8-9-20(21)32-23(22)24(31)28-14/h4-9,11,13-14,25H,10,12H2,1-3H3,(H,28,31)/b5-4+/t14-/m1/s1	GXJXOYJQXJANPO-ISZGNANSSA-N	688895	(R,E)-3-(6-(3-(dimethylamino)prop-1-en-1-yl)pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-115	MAP kinase-activated protein kinase 2	Homo sapiens		 37.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688895	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688895&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430086	504490565							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433712	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(c2)C(=C)CN2CCCC2)C(=O)N1	InChI=1S/C27H27N5OS/c1-16(15-32-11-3-4-12-32)22-13-18(9-10-28-22)20-6-5-19-21(31-20)7-8-23-24(19)25-26(34-23)27(33)30-17(2)14-29-25/h5-10,13,17,29H,1,3-4,11-12,14-15H2,2H3,(H,30,33)/t17-/m1/s1	RWRSVHUIDMAEHB-QGZVFWFLSA-N	688896	(R)-10-methyl-3-(2-(3-(pyrrolidin-1-yl)prop-1-en-2-yl)pyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-116	MAP kinase-activated protein kinase 2	Homo sapiens		 6.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688896	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688896&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430087	504490566							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433713	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(c2)C(=C)CN(C)C)C(=O)N1	InChI=1S/C25H25N5OS/c1-14(13-30(3)4)20-11-16(9-10-26-20)18-6-5-17-19(29-18)7-8-21-22(17)23-24(32-21)25(31)28-15(2)12-27-23/h5-11,15,27H,1,12-13H2,2-4H3,(H,28,31)/t15-/m1/s1	FSEUONAMDJCUDY-OAHLLOKOSA-N	688897	(R)-3-(2-(3-(dimethylamino)prop-1-en-2-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-117	MAP kinase-activated protein kinase 2	Homo sapiens		 6.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688897	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688897&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430088	504490567							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433714	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nnc2OCCN2CCCC2)C(=O)N1	InChI=1S/C27H28N6O2S/c1-3-17-14-19(27(32-31-17)35-13-12-33-10-4-5-11-33)21-7-6-18-20(30-21)8-9-22-23(18)24-25(36-22)26(34)29-16(2)15-28-24/h3,6-9,14,16,28H,1,4-5,10-13,15H2,2H3,(H,29,34)/t16-/m1/s1	KQYQIJVQCDCOJY-MRXNPFEDSA-N	688898	(R)-10-methyl-3-(3-(2-(pyrrolidin-1-yl)ethoxy)-6-vinylpyridazin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-118	MAP kinase-activated protein kinase 2	Homo sapiens		 28.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688898	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688898&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541964	504490568							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433715	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nnc2OCCN2CCCC2)C(=O)N1	InChI=1S/C25H25ClN6O2S/c1-14-13-27-22-21-15-4-5-18(29-17(15)6-7-19(21)35-23(22)24(33)28-14)16-12-20(26)30-31-25(16)34-11-10-32-8-2-3-9-32/h4-7,12,14,27H,2-3,8-11,13H2,1H3,(H,28,33)/t14-/m1/s1	OPUHQGPVIVKKTM-CQSZACIVSA-N	688899	(R)-3-(6-chloro-3-(2-(pyrrolidin-1-yl)ethoxy)pyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-119	MAP kinase-activated protein kinase 2	Homo sapiens		 981							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688899	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688899&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542148	504490569							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433716	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nnc2OCCN2CCCC2)C#C)C(=O)N1	InChI=1S/C27H26N6O2S/c1-3-17-14-19(27(32-31-17)35-13-12-33-10-4-5-11-33)21-7-6-18-20(30-21)8-9-22-23(18)24-25(36-22)26(34)29-16(2)15-28-24/h1,6-9,14,16,28H,4-5,10-13,15H2,2H3,(H,29,34)/t16-/m1/s1	VEDDMAQWBXLXLT-MRXNPFEDSA-N	688900	(R)-3-(6-ethynyl-3-(2-(pyrrolidin-1-yl)ethoxy)pyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-120	MAP kinase-activated protein kinase 2	Homo sapiens		 45.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688900	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688900&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542124	504490570							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433717	COC1CCN(Cc2cc(cc(C=C)n2)-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C29H31N5O2S/c1-4-19-13-18(14-20(32-19)16-34-11-9-21(36-3)10-12-34)23-6-5-22-24(33-23)7-8-25-26(22)27-28(37-25)29(35)31-17(2)15-30-27/h4-8,13-14,17,21,30H,1,9-12,15-16H2,2-3H3,(H,31,35)/t17-/m1/s1	LTPUVIRHJZGDHQ-QGZVFWFLSA-N	688901	(R)-3-(2-((4-methoxypiperidin-1-yl)methyl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-121	MAP kinase-activated protein kinase 2	Homo sapiens		 11.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688901	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688901&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430089	504490571							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433718	COC1CCN(Cc2cc(cc(n2)C#C)-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C29H29N5O2S/c1-4-19-13-18(14-20(32-19)16-34-11-9-21(36-3)10-12-34)23-6-5-22-24(33-23)7-8-25-26(22)27-28(37-25)29(35)31-17(2)15-30-27/h1,5-8,13-14,17,21,30H,9-12,15-16H2,2-3H3,(H,31,35)/t17-/m1/s1	YZJKUXOKVBMAQN-QGZVFWFLSA-N	688902	(R)-3-(2-ethynyl-6-((4-methoxypiperidin-1-yl)methyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-122	MAP kinase-activated protein kinase 2	Homo sapiens		 40.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688902	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688902&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430090	504490572							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433719	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCC(F)(F)CC3)nc(C=C)c2)C(=O)N1	InChI=1S/C28H27F2N5OS/c1-3-18-12-17(13-19(33-18)15-35-10-8-28(29,30)9-11-35)21-5-4-20-22(34-21)6-7-23-24(20)25-26(37-23)27(36)32-16(2)14-31-25/h3-7,12-13,16,31H,1,8-11,14-15H2,2H3,(H,32,36)/t16-/m1/s1	ADLZSLXFBIMKSF-MRXNPFEDSA-N	688903	(R)-3-(2-((4,4-difluoropiperidin-1-yl)methyl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-123	MAP kinase-activated protein kinase 2	Homo sapiens		 31.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688903	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688903&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430091	504490573							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433720	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCC(F)(F)CC3)nc(c2)C#C)C(=O)N1	InChI=1S/C28H25F2N5OS/c1-3-18-12-17(13-19(33-18)15-35-10-8-28(29,30)9-11-35)21-5-4-20-22(34-21)6-7-23-24(20)25-26(37-23)27(36)32-16(2)14-31-25/h1,4-7,12-13,16,31H,8-11,14-15H2,2H3,(H,32,36)/t16-/m1/s1	LMQLFLWGIYEHSF-MRXNPFEDSA-N	688904	(R)-3-(2-((4,4-difluoropiperidin-1-yl)methyl)-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-124	MAP kinase-activated protein kinase 2	Homo sapiens		 125							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688904	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688904&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430092	504490574							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433721	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCN(C)CC3)nc(C=C)c2)C(=O)N1	InChI=1S/C28H30N6OS/c1-4-19-13-18(14-20(31-19)16-34-11-9-33(3)10-12-34)22-6-5-21-23(32-22)7-8-24-25(21)26-27(36-24)28(35)30-17(2)15-29-26/h4-8,13-14,17,29H,1,9-12,15-16H2,2-3H3,(H,30,35)/t17-/m1/s1	SWFPIQSGYWDQEG-QGZVFWFLSA-N	688905	(R)-10-methyl-3-(2-((4-methylpiperazin-1-yl)methyl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-125	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688905	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688905&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430093	504490575							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433722	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCN(C)CC3)nc(c2)C#C)C(=O)N1	InChI=1S/C28H28N6OS/c1-4-19-13-18(14-20(31-19)16-34-11-9-33(3)10-12-34)22-6-5-21-23(32-22)7-8-24-25(21)26-27(36-24)28(35)30-17(2)15-29-26/h1,5-8,13-14,17,29H,9-12,15-16H2,2-3H3,(H,30,35)/t17-/m1/s1	KRWYXHVGWOAVMD-QGZVFWFLSA-N	688906	(R)-3-(2-ethynyl-6-((4-methylpiperazin-1-yl)methyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-126	MAP kinase-activated protein kinase 2	Homo sapiens		 34.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688906	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688906&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430094	504490576							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433723	COc1nnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H19N5O2S/c1-4-12-9-14(22(29-3)27-26-12)16-6-5-13-15(25-16)7-8-17-18(13)19-20(30-17)21(28)24-11(2)10-23-19/h4-9,11,23H,1,10H2,2-3H3,(H,24,28)/t11-/m1/s1	DHCHMLYGPFHTQJ-LLVKDONJSA-N	688907	(R)-3-(3-methoxy-6-vinylpyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-127	MAP kinase-activated protein kinase 2	Homo sapiens		 50.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688907	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688907&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542029	504490577							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433724	CNc1nnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C22H20N6OS/c1-4-12-9-14(21(23-3)28-27-12)16-6-5-13-15(26-16)7-8-17-18(13)19-20(30-17)22(29)25-11(2)10-24-19/h4-9,11,24H,1,10H2,2-3H3,(H,23,28)(H,25,29)/t11-/m1/s1	AGFVUKSTSQBNOK-LLVKDONJSA-N	688908	(R)-10-methyl-3-(3-(methylamino)-6-vinylpyridazin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-128	MAP kinase-activated protein kinase 2	Homo sapiens		 19.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688908	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688908&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542277	504490578							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433725	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nnc2N(C)C)C(=O)N1	InChI=1S/C23H22N6OS/c1-5-13-10-15(22(28-27-13)29(3)4)17-7-6-14-16(26-17)8-9-18-19(14)20-21(31-18)23(30)25-12(2)11-24-20/h5-10,12,24H,1,11H2,2-4H3,(H,25,30)/t12-/m1/s1	XGAWZPVBAFCZDI-GFCCVEGCSA-N	688909	(R)-3-(3-(dimethylamino)-6-vinylpyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-129	MAP kinase-activated protein kinase 2	Homo sapiens		 106							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688909	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688909&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542137	504490579							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433726	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2C(F)F)C(=O)N1	InChI=1S/C23H18F2N4OS/c1-3-12-8-14(15(10-26-12)22(24)25)17-5-4-13-16(29-17)6-7-18-19(13)20-21(31-18)23(30)28-11(2)9-27-20/h3-8,10-11,22,27H,1,9H2,2H3,(H,28,30)/t11-/m1/s1	JRWMTUSHUREILA-LLVKDONJSA-N	688910	(R)-3-(5-(difluoromethyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-130	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688910	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688910&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542373	504490580							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433727	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(c2)C(=C)CN2CCOCC2)C(=O)N1	InChI=1S/C27H27N5O2S/c1-16(15-32-9-11-34-12-10-32)22-13-18(7-8-28-22)20-4-3-19-21(31-20)5-6-23-24(19)25-26(35-23)27(33)30-17(2)14-29-25/h3-8,13,17,29H,1,9-12,14-15H2,2H3,(H,30,33)/t17-/m1/s1	JWOWVWPODVNPLN-QGZVFWFLSA-N	688911	(R)-10-methyl-3-(2-(3-morpholinoprop-1-en-2-yl)pyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-131	MAP kinase-activated protein kinase 2	Homo sapiens		 3.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688911	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688911&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430095	504490581							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433728	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)nnc2OCCN2CCOCC2)C(=O)N1	InChI=1S/C25H25ClN6O3S/c1-14-13-27-22-21-15-2-3-18(29-17(15)4-5-19(21)36-23(22)24(33)28-14)16-12-20(26)30-31-25(16)35-11-8-32-6-9-34-10-7-32/h2-5,12,14,27H,6-11,13H2,1H3,(H,28,33)/t14-/m1/s1	MMWJNEQHYXXMQT-CQSZACIVSA-N	688912	(R)-3-(6-chloro-3-(2-morpholinoethoxy)pyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-132	MAP kinase-activated protein kinase 2	Homo sapiens		 912							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688912	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688912&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542061	504490582							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433729	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nnc2OCCN2CCOCC2)C(=O)N1	InChI=1S/C27H28N6O3S/c1-3-17-14-19(27(32-31-17)36-13-10-33-8-11-35-12-9-33)21-5-4-18-20(30-21)6-7-22-23(18)24-25(37-22)26(34)29-16(2)15-28-24/h3-7,14,16,28H,1,8-13,15H2,2H3,(H,29,34)/t16-/m1/s1	NVXRKYFORQERFU-MRXNPFEDSA-N	688913	(R)-10-methyl-3-(3-(2-morpholinoethoxy)-6-vinylpyridazin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-133	MAP kinase-activated protein kinase 2	Homo sapiens		 255							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688913	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688913&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542379	504490583							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433730	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nnc2OCCN2CCOCC2)C#C)C(=O)N1	InChI=1S/C27H26N6O3S/c1-3-17-14-19(27(32-31-17)36-13-10-33-8-11-35-12-9-33)21-5-4-18-20(30-21)6-7-22-23(18)24-25(37-22)26(34)29-16(2)15-28-24/h1,4-7,14,16,28H,8-13,15H2,2H3,(H,29,34)/t16-/m1/s1	FRUNFRCJEUVKFO-MRXNPFEDSA-N	688914	(R)-3-(6-ethynyl-3-(2-morpholinoethoxy)pyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-134	MAP kinase-activated protein kinase 2	Homo sapiens		 137							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688914	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688914&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541884	504490584							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433731	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(c2)C#CC(C)(C)N)C(=O)N1	InChI=1S/C25H23N5OS/c1-14-13-28-22-21-17-4-5-18(15-9-11-27-16(12-15)8-10-25(2,3)26)30-19(17)6-7-20(21)32-23(22)24(31)29-14/h4-7,9,11-12,14,28H,13,26H2,1-3H3,(H,29,31)/t14-/m1/s1	HKRFWZRSIUXYOG-CQSZACIVSA-N	688915	(R)-3-(2-(3-amino-3-methylbut-1-yn-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-135	MAP kinase-activated protein kinase 2	Homo sapiens		 15.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688915	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688915&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430096	504490585							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433732	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nnc2C)C(=O)N1	InChI=1S/C22H19N5OS/c1-4-13-9-15(12(3)26-27-13)17-6-5-14-16(25-17)7-8-18-19(14)20-21(29-18)22(28)24-11(2)10-23-20/h4-9,11,23H,1,10H2,2-3H3,(H,24,28)/t11-/m1/s1	PUCLLMWLMLGNTN-LLVKDONJSA-N	688916	(R)-10-methyl-3-(3-methyl-6-vinylpyridazin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-136	MAP kinase-activated protein kinase 2	Homo sapiens		 9.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688916	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688916&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542260	504490586							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433733	COC(=O)c1nnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H19N5O3S/c1-4-12-9-14(19(28-27-12)23(30)31-3)16-6-5-13-15(26-16)7-8-17-18(13)20-21(32-17)22(29)25-11(2)10-24-20/h4-9,11,24H,1,10H2,2-3H3,(H,25,29)/t11-/m1/s1	YPFNZJJHCGKEGV-LLVKDONJSA-N	688917	US20240190890, Compound I-137::methyl (R)-4-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)-6-vinylpyridazine-3-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		 3.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688917	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688917&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542285	504490587							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433734	COc1nnc(cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1)C(=C)CN1CCOCC1	InChI=1S/C27H28N6O3S/c1-15(14-33-8-10-36-11-9-33)21-12-18(27(35-3)32-31-21)20-5-4-17-19(30-20)6-7-22-23(17)24-25(37-22)26(34)29-16(2)13-28-24/h4-7,12,16,28H,1,8-11,13-14H2,2-3H3,(H,29,34)/t16-/m1/s1	KCTMDNGIKPHXPN-MRXNPFEDSA-N	688918	(R)-3-(3-methoxy-6-(3-morpholinoprop-1-en-2-yl)pyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-138	MAP kinase-activated protein kinase 2	Homo sapiens		 96.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688918	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688918&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430097	504490588							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433735	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncn2)C(=C)CN2CCOCC2)C(=O)N1	InChI=1S/C26H26N6O2S/c1-15(13-32-7-9-34-10-8-32)20-11-21(29-14-28-20)19-4-3-17-18(31-19)5-6-22-23(17)24-25(35-22)26(33)30-16(2)12-27-24/h3-6,11,14,16,27H,1,7-10,12-13H2,2H3,(H,30,33)/t16-/m1/s1	MGRAOTDXRNYSHM-MRXNPFEDSA-N	688919	(R)-10-methyl-3-(6-(3-morpholinoprop-1-en-2-yl)pyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-139	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688919	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688919&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430098	504490589							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433736	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCOCC3)nc(C=C)c2)C(=O)N1	InChI=1S/C27H27N5O2S/c1-3-18-12-17(13-19(30-18)15-32-8-10-34-11-9-32)21-5-4-20-22(31-21)6-7-23-24(20)25-26(35-23)27(33)29-16(2)14-28-25/h3-7,12-13,16,28H,1,8-11,14-15H2,2H3,(H,29,33)/t16-/m1/s1	BMQYAZWDICUYDI-MRXNPFEDSA-N	688920	(R)-10-methyl-3-(2-(morpholinomethyl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-140	MAP kinase-activated protein kinase 2	Homo sapiens		 14.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688920	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688920&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542169	504490590							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433737	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCC4(CC4(F)F)CC3)nc(C=C)c2)C(=O)N1	InChI=1S/C30H29F2N5OS/c1-3-19-12-18(13-20(35-19)15-37-10-8-29(9-11-37)16-30(29,31)32)22-5-4-21-23(36-22)6-7-24-25(21)26-27(39-24)28(38)34-17(2)14-33-26/h3-7,12-13,17,33H,1,8-11,14-16H2,2H3,(H,34,38)/t17-/m1/s1	KOULXTCAIAQQSF-QGZVFWFLSA-N	688921	(R)-3-(2-((1,1-difluoro-6-azaspiro[2.5]octan-6-yl)methyl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-141	MAP kinase-activated protein kinase 2	Homo sapiens		 111							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688921	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688921&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430099	504490591							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433738	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2C)C(=O)N1	InChI=1S/C23H20N4OS/c1-4-14-9-16(12(2)10-24-14)18-6-5-15-17(27-18)7-8-19-20(15)21-22(29-19)23(28)26-13(3)11-25-21/h4-10,13,25H,1,11H2,2-3H3,(H,26,28)/t13-/m1/s1	UIPAEGAJTRBGJU-CYBMUJFWSA-N	688889	(R)-10-methyl-3-(5-methyl-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-109::US20240190890, Compound I-142::US20240190890, Compound I-249	MAP kinase-activated protein kinase 2	Homo sapiens		 9.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541925	504490559							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433739	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2Cl)C(=O)N1	InChI=1S/C22H17ClN4OS/c1-3-12-8-14(15(23)10-24-12)17-5-4-13-16(27-17)6-7-18-19(13)20-21(29-18)22(28)26-11(2)9-25-20/h3-8,10-11,25H,1,9H2,2H3,(H,26,28)/t11-/m1/s1	UCDYBUDRRVOLLY-LLVKDONJSA-N	688923	(R)-3-(5-chloro-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-143	MAP kinase-activated protein kinase 2	Homo sapiens		 59.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688923	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688923&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542393	504490592							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433740	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncc2Cl)C#C)C(=O)N1	InChI=1S/C22H15ClN4OS/c1-3-12-8-14(15(23)10-24-12)17-5-4-13-16(27-17)6-7-18-19(13)20-21(29-18)22(28)26-11(2)9-25-20/h1,4-8,10-11,25H,9H2,2H3,(H,26,28)/t11-/m1/s1	FNDVFSVVKMGIMM-LLVKDONJSA-N	688924	(R)-3-(5-chloro-2-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-144	MAP kinase-activated protein kinase 2	Homo sapiens		 678							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688924	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688924&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542290	504490593							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433741	COc1nnc(\C=C\CN(C)C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H26N6O2S/c1-14-13-26-22-21-16-7-8-19(28-18(16)9-10-20(21)34-23(22)24(32)27-14)17-12-15(6-5-11-31(2)3)29-30-25(17)33-4/h5-10,12,14,26H,11,13H2,1-4H3,(H,27,32)/b6-5+/t14-/m1/s1	QHMFUQLWIACBQV-VBROQKIQSA-N	688925	(R,E)-3-(6-(3-(dimethylamino)prop-1-en-1-yl)-3-methoxypyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-145	MAP kinase-activated protein kinase 2	Homo sapiens		 273							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688925	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688925&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430100	504490594							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433742	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2c(C=C)cnn2C)C(=O)N1	InChI=1S/C21H19N5OS/c1-4-12-10-23-26(3)19(12)15-6-5-13-14(25-15)7-8-16-17(13)18-20(28-16)21(27)24-11(2)9-22-18/h4-8,10-11,22H,1,9H2,2-3H3,(H,24,27)/t11-/m1/s1	ZHWJMPTWQQQPGB-LLVKDONJSA-N	688926	(R)-10-methyl-3-(1-methyl-4-vinyl-1H-pyrazol-5-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-146	MAP kinase-activated protein kinase 2	Homo sapiens		 499							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688926	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688926&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542110	504490595							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433743	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2ccc(C=C)n2)C(=O)N1	InChI=1S/C20H17N5OS/c1-3-12-8-9-25(24-12)16-7-4-13-14(23-16)5-6-15-17(13)18-19(27-15)20(26)22-11(2)10-21-18/h3-9,11,21H,1,10H2,2H3,(H,22,26)/t11-/m1/s1	HSEROCVHILWAMK-LLVKDONJSA-N	688927	(R)-10-methyl-3-(3-vinyl-1H-pyrazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-147	MAP kinase-activated protein kinase 2	Homo sapiens		 104							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688927	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688927&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542050	504490596							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433744	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2cc(C=C)cn2)C(=O)N1	InChI=1S/C20H17N5OS/c1-3-12-9-22-25(10-12)16-7-4-13-14(24-16)5-6-15-17(13)18-19(27-15)20(26)23-11(2)8-21-18/h3-7,9-11,21H,1,8H2,2H3,(H,23,26)/t11-/m1/s1	RXSUNGJNNIOTNW-LLVKDONJSA-N	688928	(R)-10-methyl-3-(4-vinyl-1H-pyrazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-148	MAP kinase-activated protein kinase 2	Homo sapiens		 101							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688928	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688928&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542263	504490597							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433745	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)cs2)C(=O)N1	InChI=1S/C20H16N4OS2/c1-3-11-9-26-20(23-11)14-5-4-12-13(24-14)6-7-15-16(12)17-18(27-15)19(25)22-10(2)8-21-17/h3-7,9-10,21H,1,8H2,2H3,(H,22,25)/t10-/m1/s1	FGXPIMCFDDFFEJ-SNVBAGLBSA-N	688929	(R)-10-methyl-3-(4-vinylthiazol-2-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-149	MAP kinase-activated protein kinase 2	Homo sapiens		 95.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688929	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688929&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541982	504490598							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433746	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnc(C=C)[nH]2)C(=O)N1	InChI=1S/C20H17N5OS/c1-3-16-21-9-14(25-16)13-5-4-11-12(24-13)6-7-15-17(11)18-19(27-15)20(26)23-10(2)8-22-18/h3-7,9-10,22H,1,8H2,2H3,(H,21,25)(H,23,26)/t10-/m1/s1	HQJUHDNSROEHOB-SNVBAGLBSA-N	688930	(R)-10-methyl-3-(2-vinyl-1H-imidazol-5-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-150	MAP kinase-activated protein kinase 2	Homo sapiens		 14.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688930	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688930&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542120	504490599							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433747	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnc(Cl)[nH]2)C(=O)N1	InChI=1S/C18H14ClN5OS/c1-8-6-20-15-14-9-2-3-11(12-7-21-18(19)24-12)23-10(9)4-5-13(14)26-16(15)17(25)22-8/h2-5,7-8,20H,6H2,1H3,(H,21,24)(H,22,25)/t8-/m1/s1	BEHCJVVOIYYKQB-MRVPVSSYSA-N	688931	(R)-3-(2-chloro-1H-imidazol-5-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-151	MAP kinase-activated protein kinase 2	Homo sapiens		 23.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688931	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688931&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542391	504490600							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433748	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2cc(Cl)cn2)C(=O)N1	InChI=1S/C18H14ClN5OS/c1-9-6-20-16-15-11-2-5-14(24-8-10(19)7-21-24)23-12(11)3-4-13(15)26-17(16)18(25)22-9/h2-5,7-9,20H,6H2,1H3,(H,22,25)/t9-/m1/s1	ZRCZMVSRZWDVQG-SECBINFHSA-N	688932	(R)-3-(4-chloro-1H-pyrazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-152	MAP kinase-activated protein kinase 2	Homo sapiens		 86.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688932	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688932&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541952	504490601							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433749	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2CN2CCOCC2)C(=O)N1	InChI=1S/C27H27N5O2S/c1-3-18-12-20(17(14-28-18)15-32-8-10-34-11-9-32)22-5-4-19-21(31-22)6-7-23-24(19)25-26(35-23)27(33)30-16(2)13-29-25/h3-7,12,14,16,29H,1,8-11,13,15H2,2H3,(H,30,33)/t16-/m1/s1	KXDITUZTZBMLCJ-MRXNPFEDSA-N	688933	(R)-10-methyl-3-(5-(morpholinomethyl)-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-153	MAP kinase-activated protein kinase 2	Homo sapiens		 23.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688933	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688933&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541977	504490602							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433750	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncc2CN2CCOCC2)C#C)C(=O)N1	InChI=1S/C27H25N5O2S/c1-3-18-12-20(17(14-28-18)15-32-8-10-34-11-9-32)22-5-4-19-21(31-22)6-7-23-24(19)25-26(35-23)27(33)30-16(2)13-29-25/h1,4-7,12,14,16,29H,8-11,13,15H2,2H3,(H,30,33)/t16-/m1/s1	JCKCJHZWXLBHKG-MRXNPFEDSA-N	688934	(R)-3-(2-ethynyl-5-(morpholinomethyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-154	MAP kinase-activated protein kinase 2	Homo sapiens		 49.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688934	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688934&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542197	504490603							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433751	COC1CCN(Cc2cnc(C=C)cc2-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)CC1	InChI=1S/C29H31N5O2S/c1-4-19-13-22(18(15-30-19)16-34-11-9-20(36-3)10-12-34)24-6-5-21-23(33-24)7-8-25-26(21)27-28(37-25)29(35)32-17(2)14-31-27/h4-8,13,15,17,20,31H,1,9-12,14,16H2,2-3H3,(H,32,35)/t17-/m1/s1	NAELSHMKTISENA-QGZVFWFLSA-N	688935	(R)-3-(5-((4-methoxypiperidin-1-yl)methyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-155	MAP kinase-activated protein kinase 2	Homo sapiens		 95.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688935	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688935&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541908	504490604							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433752	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCOCC2)C(=O)N1	InChI=1S/C26H25N5O2S/c1-3-17-12-16(13-22(29-17)31-8-10-33-11-9-31)19-5-4-18-20(30-19)6-7-21-23(18)24-25(34-21)26(32)28-15(2)14-27-24/h3-7,12-13,15,27H,1,8-11,14H2,2H3,(H,28,32)/t15-/m1/s1	DSKNNOOEURGECC-OAHLLOKOSA-N	688936	(R)-10-methyl-3-(2-morpholino-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-156	MAP kinase-activated protein kinase 2	Homo sapiens		 23.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688936	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688936&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542271	504490605							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433753	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CCOCC2)C#C)C(=O)N1	InChI=1S/C26H23N5O2S/c1-3-17-12-16(13-22(29-17)31-8-10-33-11-9-31)19-5-4-18-20(30-19)6-7-21-23(18)24-25(34-21)26(32)28-15(2)14-27-24/h1,4-7,12-13,15,27H,8-11,14H2,2H3,(H,28,32)/t15-/m1/s1	SOLIEJNDAWYGRK-OAHLLOKOSA-N	688937	(R)-3-(2-ethynyl-6-morpholinopyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-157	MAP kinase-activated protein kinase 2	Homo sapiens		 214							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688937	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688937&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542300	504490606							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433754	COC1CCN(CC1)c1cc(cc(C=C)n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C28H29N5O2S/c1-4-18-13-17(14-24(31-18)33-11-9-19(35-3)10-12-33)21-6-5-20-22(32-21)7-8-23-25(20)26-27(36-23)28(34)30-16(2)15-29-26/h4-8,13-14,16,19,29H,1,9-12,15H2,2-3H3,(H,30,34)/t16-/m1/s1	GGADGERMSFVZDV-MRXNPFEDSA-N	688938	(R)-3-(2-(4-methoxypiperidin-1-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-158	MAP kinase-activated protein kinase 2	Homo sapiens		 38.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688938	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688938&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430101	504490607							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433755	COC1CCN(CC1)c1cc(cc(n1)C#C)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C28H27N5O2S/c1-4-18-13-17(14-24(31-18)33-11-9-19(35-3)10-12-33)21-6-5-20-22(32-21)7-8-23-25(20)26-27(36-23)28(34)30-16(2)15-29-26/h1,5-8,13-14,16,19,29H,9-12,15H2,2-3H3,(H,30,34)/t16-/m1/s1	PNLAJHBCGORDBA-MRXNPFEDSA-N	688939	(R)-3-(2-ethynyl-6-(4-methoxypiperidin-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-159	MAP kinase-activated protein kinase 2	Homo sapiens		 189							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688939	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688939&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542348	504490608							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433756	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(Cl)ncc2C#N)C(=O)N1	InChI=1S/C21H14ClN5OS/c1-10-8-25-19-18-12-2-3-15(13-6-17(22)24-9-11(13)7-23)27-14(12)4-5-16(18)29-20(19)21(28)26-10/h2-6,9-10,25H,8H2,1H3,(H,26,28)/t10-/m1/s1	BKCGRXWDZNSECE-SNVBAGLBSA-N	688940	(R)-6-chloro-4-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)nicotinonitrile::US20240190890, Compound I-160	MAP kinase-activated protein kinase 2	Homo sapiens		 3.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688940	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688940&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542340	504490609							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433757	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2C#N)C(=O)N1	InChI=1S/C23H17N5OS/c1-3-14-8-16(13(9-24)11-25-14)18-5-4-15-17(28-18)6-7-19-20(15)21-22(30-19)23(29)27-12(2)10-26-21/h3-8,11-12,26H,1,10H2,2H3,(H,27,29)/t12-/m1/s1	BFFQFIKOBBAGPW-GFCCVEGCSA-N	688941	(R)-4-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)-6-vinylnicotinonitrile::US20240190890, Compound I-161	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688941	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688941&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430102	504490610							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433758	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(ncc2C#N)C#C)C(=O)N1	InChI=1S/C23H15N5OS/c1-3-14-8-16(13(9-24)11-25-14)18-5-4-15-17(28-18)6-7-19-20(15)21-22(30-19)23(29)27-12(2)10-26-21/h1,4-8,11-12,26H,10H2,2H3,(H,27,29)/t12-/m1/s1	DMNATCTWKGWGCB-GFCCVEGCSA-N	688942	(R)-6-ethynyl-4-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)nicotinonitrile::US20240190890, Compound I-162	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688942	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688942&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542331	504490611							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433759	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cncc(C=C)n2)C(=O)N1	InChI=1S/C21H17N5OS/c1-3-12-9-22-10-16(25-12)15-5-4-13-14(26-15)6-7-17-18(13)19-20(28-17)21(27)24-11(2)8-23-19/h3-7,9-11,23H,1,8H2,2H3,(H,24,27)/t11-/m1/s1	YBTDVWPEJPMSRK-LLVKDONJSA-N	688943	(R)-10-methyl-3-(6-vinylpyrazin-2-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-163	MAP kinase-activated protein kinase 2	Homo sapiens		 109							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688943	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688943&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542354	504490612							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433760	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2ccnc2C=C)C(=O)N1	InChI=1S/C20H17N5OS/c1-3-15-21-8-9-25(15)16-7-4-12-13(24-16)5-6-14-17(12)18-19(27-14)20(26)23-11(2)10-22-18/h3-9,11,22H,1,10H2,2H3,(H,23,26)/t11-/m1/s1	GDOTTYIWCBDASJ-LLVKDONJSA-N	688944	(R)-10-methyl-3-(2-vinyl-1H-imidazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-164	MAP kinase-activated protein kinase 2	Homo sapiens		 1.000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688944	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688944&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542238	504490613							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433761	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2ccc(Cl)n2)C(=O)N1	InChI=1S/C18H14ClN5OS/c1-9-8-20-16-15-10-2-5-14(24-7-6-13(19)23-24)22-11(10)3-4-12(15)26-17(16)18(25)21-9/h2-7,9,20H,8H2,1H3,(H,21,25)/t9-/m1/s1	VPECMCKGBMPYFL-SECBINFHSA-N	688945	(R)-3-(3-chloro-1H-pyrazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-165	MAP kinase-activated protein kinase 2	Homo sapiens		 81.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688945	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688945&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542350	504490614							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433762	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnc(C)c(C=C)n2)C(=O)N1	InChI=1S/C22H19N5OS/c1-4-14-12(3)23-10-17(26-14)16-6-5-13-15(27-16)7-8-18-19(13)20-21(29-18)22(28)25-11(2)9-24-20/h4-8,10-11,24H,1,9H2,2-3H3,(H,25,28)/t11-/m1/s1	DCSZTJUOHIUSJY-LLVKDONJSA-N	688946	(R)-10-methyl-3-(5-methyl-6-vinylpyrazin-2-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-166	MAP kinase-activated protein kinase 2	Homo sapiens		 181							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688946	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688946&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542267	504490615							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433763	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCC(F)(F)CC2)C(=O)N1	InChI=1S/C27H25F2N5OS/c1-3-17-12-16(13-22(32-17)34-10-8-27(28,29)9-11-34)19-5-4-18-20(33-19)6-7-21-23(18)24-25(36-21)26(35)31-15(2)14-30-24/h3-7,12-13,15,30H,1,8-11,14H2,2H3,(H,31,35)/t15-/m1/s1	QZIBHGQOFQKSQP-OAHLLOKOSA-N	688947	(R)-3-(2-(4,4-difluoropiperidin-1-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-168	MAP kinase-activated protein kinase 2	Homo sapiens		 260							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688947	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688947&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430103	504490616							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433764	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCOCC3)nc(c2)C#C)C(=O)N1	InChI=1S/C27H25N5O2S/c1-3-18-12-17(13-19(30-18)15-32-8-10-34-11-9-32)21-5-4-20-22(31-21)6-7-23-24(20)25-26(35-23)27(33)29-16(2)14-28-25/h1,4-7,12-13,16,28H,8-11,14-15H2,2H3,(H,29,33)/t16-/m1/s1	USXRZOUIRFOVTO-MRXNPFEDSA-N	688948	(R)-3-(2-ethynyl-6-(morpholinomethyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-169	MAP kinase-activated protein kinase 2	Homo sapiens		 39.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688948	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688948&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542307	504490617							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433765	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nnc2C)C#C)C(=O)N1	InChI=1S/C22H17N5OS/c1-4-13-9-15(12(3)26-27-13)17-6-5-14-16(25-17)7-8-18-19(14)20-21(29-18)22(28)24-11(2)10-23-20/h1,5-9,11,23H,10H2,2-3H3,(H,24,28)/t11-/m1/s1	YTPQITVTXNCAQF-LLVKDONJSA-N	688949	(R)-3-(6-ethynyl-3-methylpyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-170	MAP kinase-activated protein kinase 2	Homo sapiens		 18.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688949	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688949&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542073	504490618							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433766	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCN(C)CC2)C(=O)N1	InChI=1S/C27H28N6OS/c1-4-18-13-17(14-23(30-18)33-11-9-32(3)10-12-33)20-6-5-19-21(31-20)7-8-22-24(19)25-26(35-22)27(34)29-16(2)15-28-25/h4-8,13-14,16,28H,1,9-12,15H2,2-3H3,(H,29,34)/t16-/m1/s1	SKVCMCBKRCIKAY-MRXNPFEDSA-N	688876	(R)-10-methyl-3-(2-(4-methylpiperazin-1-yl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-171::US20240190890, Compound I-96	MAP kinase-activated protein kinase 2	Homo sapiens		 13.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688876	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688876&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430075	504490546							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433767	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CCN(C)CC2)C#C)C(=O)N1	InChI=1S/C27H26N6OS/c1-4-18-13-17(14-23(30-18)33-11-9-32(3)10-12-33)20-6-5-19-21(31-20)7-8-22-24(19)25-26(35-22)27(34)29-16(2)15-28-25/h1,5-8,13-14,16,28H,9-12,15H2,2-3H3,(H,29,34)/t16-/m1/s1	WNOGJJHITUPYLM-MRXNPFEDSA-N	688875	(R)-3-(2-ethynyl-6-(4-methylpiperazin-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-172::US20240190890, Compound I-95	MAP kinase-activated protein kinase 2	Homo sapiens		 97.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688875	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688875&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430074	504490545							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433768	CCN1CCN(CC1)c1cc(cc(C=C)n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C28H30N6OS/c1-4-19-14-18(15-24(31-19)34-12-10-33(5-2)11-13-34)21-7-6-20-22(32-21)8-9-23-25(20)26-27(36-23)28(35)30-17(3)16-29-26/h4,6-9,14-15,17,29H,1,5,10-13,16H2,2-3H3,(H,30,35)/t17-/m1/s1	CGFSHUFEMKLMRW-QGZVFWFLSA-N	688952	(R)-3-(2-(4-ethylpiperazin-1-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-173	MAP kinase-activated protein kinase 2	Homo sapiens		 35.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688952	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688952&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430104	504490619							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433769	CCN1CCN(CC1)c1cc(cc(n1)C#C)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C28H28N6OS/c1-4-19-14-18(15-24(31-19)34-12-10-33(5-2)11-13-34)21-7-6-20-22(32-21)8-9-23-25(20)26-27(36-23)28(35)30-17(3)16-29-26/h1,6-9,14-15,17,29H,5,10-13,16H2,2-3H3,(H,30,35)/t17-/m1/s1	ZOZYMPWQADGQEW-QGZVFWFLSA-N	688953	(R)-3-(2-(4-ethylpiperazin-1-yl)-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-174	MAP kinase-activated protein kinase 2	Homo sapiens		 98.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688953	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688953&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430105	504490620							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433770	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCNCC2)C(=O)N1	InChI=1S/C26H26N6OS/c1-3-17-12-16(13-22(30-17)32-10-8-27-9-11-32)19-5-4-18-20(31-19)6-7-21-23(18)24-25(34-21)26(33)29-15(2)14-28-24/h3-7,12-13,15,27-28H,1,8-11,14H2,2H3,(H,29,33)/t15-/m1/s1	ILDTUYKXNHTPFK-OAHLLOKOSA-N	688954	(R)-10-methyl-3-(2-(piperazin-1-yl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-175	MAP kinase-activated protein kinase 2	Homo sapiens		 10.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688954	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688954&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542396	504490621							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433771	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CCNCC2)C#C)C(=O)N1	InChI=1S/C26H24N6OS/c1-3-17-12-16(13-22(30-17)32-10-8-27-9-11-32)19-5-4-18-20(31-19)6-7-21-23(18)24-25(34-21)26(33)29-15(2)14-28-24/h1,4-7,12-13,15,27-28H,8-11,14H2,2H3,(H,29,33)/t15-/m1/s1	AKJGETYOYAYORZ-OAHLLOKOSA-N	688955	(R)-3-(2-ethynyl-6-(piperazin-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-176	MAP kinase-activated protein kinase 2	Homo sapiens		 70.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688955	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688955&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541915	504490622							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433772	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCCCC2)C(=O)N1	InChI=1S/C27H27N5OS/c1-3-18-13-17(14-23(30-18)32-11-5-4-6-12-32)20-8-7-19-21(31-20)9-10-22-24(19)25-26(34-22)27(33)29-16(2)15-28-25/h3,7-10,13-14,16,28H,1,4-6,11-12,15H2,2H3,(H,29,33)/t16-/m1/s1	WLOZPARFWLDYFS-MRXNPFEDSA-N	688956	(R)-10-methyl-3-(2-(piperidin-1-yl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-177	MAP kinase-activated protein kinase 2	Homo sapiens		 140							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688956	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688956&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542351	504490623							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433773	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CCCCC2)C#C)C(=O)N1	InChI=1S/C27H25N5OS/c1-3-18-13-17(14-23(30-18)32-11-5-4-6-12-32)20-8-7-19-21(31-20)9-10-22-24(19)25-26(34-22)27(33)29-16(2)15-28-25/h1,7-10,13-14,16,28H,4-6,11-12,15H2,2H3,(H,29,33)/t16-/m1/s1	UUROORGNZGHBTC-MRXNPFEDSA-N	688957	(R)-3-(2-ethynyl-6-(piperidin-1-yl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-178	MAP kinase-activated protein kinase 2	Homo sapiens		 185							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688957	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688957&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542111	504490624							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433774	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCC2)C(=O)N1	InChI=1S/C25H23N5OS/c1-3-16-11-15(12-21(28-16)30-9-4-10-30)18-6-5-17-19(29-18)7-8-20-22(17)23-24(32-20)25(31)27-14(2)13-26-23/h3,5-8,11-12,14,26H,1,4,9-10,13H2,2H3,(H,27,31)/t14-/m1/s1	IVOMDRORAAAKBZ-CQSZACIVSA-N	688958	(R)-3-(2-(azetidin-1-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-179	MAP kinase-activated protein kinase 2	Homo sapiens		 11.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688958	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688958&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541973	504490625							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433775	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CCC2)C#C)C(=O)N1	InChI=1S/C25H21N5OS/c1-3-16-11-15(12-21(28-16)30-9-4-10-30)18-6-5-17-19(29-18)7-8-20-22(17)23-24(32-20)25(31)27-14(2)13-26-23/h1,5-8,11-12,14,26H,4,9-10,13H2,2H3,(H,27,31)/t14-/m1/s1	OZDNPRSZRWQZPY-CQSZACIVSA-N	688959	(R)-3-(2-(azetidin-1-yl)-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-180	MAP kinase-activated protein kinase 2	Homo sapiens		 184							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688959	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688959&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542370	504490626							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433776	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)cnc2C)C(=O)N1	InChI=1S/C22H19N5OS/c1-4-13-10-23-12(3)19(26-13)16-6-5-14-15(27-16)7-8-17-18(14)20-21(29-17)22(28)25-11(2)9-24-20/h4-8,10-11,24H,1,9H2,2-3H3,(H,25,28)/t11-/m1/s1	JUZZGBPNGCMSBZ-LLVKDONJSA-N	688960	(R)-10-methyl-3-(3-methyl-6-vinylpyrazin-2-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-181	MAP kinase-activated protein kinase 2	Homo sapiens		 39.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688960	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688960&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542125	504490627							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433777	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CCC(F)(F)CC2)C#C)C(=O)N1	InChI=1S/C27H23F2N5OS/c1-3-17-12-16(13-22(32-17)34-10-8-27(28,29)9-11-34)19-5-4-18-20(33-19)6-7-21-23(18)24-25(36-21)26(35)31-15(2)14-30-24/h1,4-7,12-13,15,30H,8-11,14H2,2H3,(H,31,35)/t15-/m1/s1	RNQFLBCTCIVJLM-OAHLLOKOSA-N	688961	(R)-3-(2-(4,4-difluoropiperidin-1-yl)-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-182	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688961	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688961&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430106	504490628							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433778	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(nc(c2)N2CC(F)(F)C2)C#C)C(=O)N1	InChI=1S/C25H19F2N5OS/c1-3-15-8-14(9-20(30-15)32-11-25(26,27)12-32)17-5-4-16-18(31-17)6-7-19-21(16)22-23(34-19)24(33)29-13(2)10-28-22/h1,4-9,13,28H,10-12H2,2H3,(H,29,33)/t13-/m1/s1	NDUPJRURTAQADU-CYBMUJFWSA-N	688962	(R)-3-(2-(3,3-difluoroazetidin-1-yl)-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-183	MAP kinase-activated protein kinase 2	Homo sapiens		 839							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688962	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688962&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430107	504490629							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433779	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CC(F)(F)C2)C(=O)N1	InChI=1S/C25H21F2N5OS/c1-3-15-8-14(9-20(30-15)32-11-25(26,27)12-32)17-5-4-16-18(31-17)6-7-19-21(16)22-23(34-19)24(33)29-13(2)10-28-22/h3-9,13,28H,1,10-12H2,2H3,(H,29,33)/t13-/m1/s1	AAVYEFCJYLTJPU-CYBMUJFWSA-N	688963	(R)-3-(2-(3,3-difluoroazetidin-1-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-184	MAP kinase-activated protein kinase 2	Homo sapiens		 175							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688963	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688963&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430108	504490630							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433780	C[C@H]1CN(Cc2cc(cc(C=C)n2)-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C[C@@H](C)O1	InChI=1S/C29H31N5O2S/c1-5-20-10-19(11-21(32-20)15-34-13-17(3)36-18(4)14-34)23-7-6-22-24(33-23)8-9-25-26(22)27-28(37-25)29(35)31-16(2)12-30-27/h5-11,16-18,30H,1,12-15H2,2-4H3,(H,31,35)/t16-,17-,18+/m1/s1	OBWCIORHCHPDPA-KURKYZTESA-N	688964	(R)-3-(2-(((2S,6R)-2,6-dimethylmorpholino)methyl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-185	MAP kinase-activated protein kinase 2	Homo sapiens		 7.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688964	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688964&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171723532	504490631							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433781	C[C@H]1CN(Cc2cc(cc(n2)C#C)-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C[C@@H](C)O1	InChI=1S/C29H29N5O2S/c1-5-20-10-19(11-21(32-20)15-34-13-17(3)36-18(4)14-34)23-7-6-22-24(33-23)8-9-25-26(22)27-28(37-25)29(35)31-16(2)12-30-27/h1,6-11,16-18,30H,12-15H2,2-4H3,(H,31,35)/t16-,17-,18+/m1/s1	YEWAPTIJMWRJSN-KURKYZTESA-N	688965	(R)-3-(2-(((2S,6R)-2,6-dimethylmorpholino)methyl)-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-186	MAP kinase-activated protein kinase 2	Homo sapiens		 26.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688965	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688965&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171723399	504490632							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433782	C[C@@H]1CN(Cc2cc(cc(C=C)n2)-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C[C@@H](C)O1	InChI=1S/C29H31N5O2S/c1-5-20-10-19(11-21(32-20)15-34-13-17(3)36-18(4)14-34)23-7-6-22-24(33-23)8-9-25-26(22)27-28(37-25)29(35)31-16(2)12-30-27/h5-11,16-18,30H,1,12-15H2,2-4H3,(H,31,35)/t16-,17-,18-/m1/s1	OBWCIORHCHPDPA-KZNAEPCWSA-N	688966	(R)-3-(2-(((2R,6R)-2,6-dimethylmorpholino)methyl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-187	MAP kinase-activated protein kinase 2	Homo sapiens		 8.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688966	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688966&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171723494	504490633							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433783	C[C@@H]1CN(Cc2cc(cc(n2)C#C)-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C[C@@H](C)O1	InChI=1S/C29H29N5O2S/c1-5-20-10-19(11-21(32-20)15-34-13-17(3)36-18(4)14-34)23-7-6-22-24(33-23)8-9-25-26(22)27-28(37-25)29(35)31-16(2)12-30-27/h1,6-11,16-18,30H,12-15H2,2-4H3,(H,31,35)/t16-,17-,18-/m1/s1	YEWAPTIJMWRJSN-KZNAEPCWSA-N	688967	(R)-3-(2-(((2R,6R)-2,6-dimethylmorpholino)methyl)-6-ethynylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-188	MAP kinase-activated protein kinase 2	Homo sapiens		 25.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688967	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688967&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430109	504490634							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433784	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCC(CC3)OC(F)(F)F)nc(C=C)c2)C(=O)N1	InChI=1S/C29H28F3N5O2S/c1-3-18-12-17(13-19(35-18)15-37-10-8-20(9-11-37)39-29(30,31)32)22-5-4-21-23(36-22)6-7-24-25(21)26-27(40-24)28(38)34-16(2)14-33-26/h3-7,12-13,16,20,33H,1,8-11,14-15H2,2H3,(H,34,38)/t16-/m1/s1	VKUJPDZXUJUFRS-MRXNPFEDSA-N	688968	(R)-10-methyl-3-(2-((4-(trifluoromethoxy)piperidin-1-yl)methyl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-189	MAP kinase-activated protein kinase 2	Homo sapiens		 206							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688968	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688968&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430110	504490635							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433785	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CN3CCC(CC3)OC(F)(F)F)nc(c2)C#C)C(=O)N1	InChI=1S/C29H26F3N5O2S/c1-3-18-12-17(13-19(35-18)15-37-10-8-20(9-11-37)39-29(30,31)32)22-5-4-21-23(36-22)6-7-24-25(21)26-27(40-24)28(38)34-16(2)14-33-26/h1,4-7,12-13,16,20,33H,8-11,14-15H2,2H3,(H,34,38)/t16-/m1/s1	ILWWQBCBTJKXOG-MRXNPFEDSA-N	688969	(R)-3-(2-ethynyl-6-((4-(trifluoromethoxy)piperidin-1-yl)methyl)pyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-190	MAP kinase-activated protein kinase 2	Homo sapiens		 402							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688969	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688969&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430111	504490636							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433786	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)nc3CCN(C)Cc23)C(=O)N1	InChI=1S/C25H24N6OS/c1-4-20-29-17-9-10-31(3)12-15(17)22(30-20)18-6-5-14-16(28-18)7-8-19-21(14)23-24(33-19)25(32)27-13(2)11-26-23/h4-8,13,26H,1,9-12H2,2-3H3,(H,27,32)/t13-/m1/s1	ANHKDEKAGRYWCB-CYBMUJFWSA-N	688970	(R)-10-methyl-3-(6-methyl-2-vinyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-191	MAP kinase-activated protein kinase 2	Homo sapiens		 289							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688970	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688970&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430112	504490637							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433787	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)nc3CCN(C)Cc23)C(=O)N1	InChI=1S/C23H21ClN6OS/c1-11-9-25-20-18-12-3-4-16(19-13-10-30(2)8-7-15(13)28-23(24)29-19)27-14(12)5-6-17(18)32-21(20)22(31)26-11/h3-6,11,25H,7-10H2,1-2H3,(H,26,31)/t11-/m1/s1	RHZGPUZQAKUGDH-LLVKDONJSA-N	688971	(R)-3-(2-chloro-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-192	MAP kinase-activated protein kinase 2	Homo sapiens		 257							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688971	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688971&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430113	504490638							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433788	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(nc3CCN(C)Cc23)C#C)C(=O)N1	InChI=1S/C25H22N6OS/c1-4-20-29-17-9-10-31(3)12-15(17)22(30-20)18-6-5-14-16(28-18)7-8-19-21(14)23-24(33-19)25(32)27-13(2)11-26-23/h1,5-8,13,26H,9-12H2,2-3H3,(H,27,32)/t13-/m1/s1	GNVVOGGATFLMJL-CYBMUJFWSA-N	688972	(R)-3-(2-ethynyl-6-methyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-193	MAP kinase-activated protein kinase 2	Homo sapiens		 526							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688972	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688972&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430114	504490639							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433789	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(C)c2C)C(=O)N1	InChI=1S/C24H22N4OS/c1-5-15-10-17(13(3)14(4)27-15)19-7-6-16-18(28-19)8-9-20-21(16)22-23(30-20)24(29)26-12(2)11-25-22/h5-10,12,25H,1,11H2,2-4H3,(H,26,29)/t12-/m1/s1	IOUCBHGBHNDCHX-GFCCVEGCSA-N	688973	(R)-3-(2,3-dimethyl-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-194	MAP kinase-activated protein kinase 2	Homo sapiens		 5.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688973	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688973&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541939	504490640							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433790	CCc1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H22N4OS/c1-4-14-12-25-15(5-2)10-17(14)19-7-6-16-18(28-19)8-9-20-21(16)22-23(30-20)24(29)27-13(3)11-26-22/h5-10,12-13,26H,2,4,11H2,1,3H3,(H,27,29)/t13-/m1/s1	LUIYQCQCXBDIJY-CYBMUJFWSA-N	688974	(R)-3-(5-ethyl-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-195	MAP kinase-activated protein kinase 2	Homo sapiens		 13.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688974	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688974&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542086	504490641							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433791	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2C2CC2)C(=O)N1	InChI=1S/C25H22N4OS/c1-3-15-10-17(18(12-26-15)14-4-5-14)20-7-6-16-19(29-20)8-9-21-22(16)23-24(31-21)25(30)28-13(2)11-27-23/h3,6-10,12-14,27H,1,4-5,11H2,2H3,(H,28,30)/t13-/m1/s1	DEODQQWVBZLXPI-CYBMUJFWSA-N	688975	(R)-3-(5-cyclopropyl-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-196	MAP kinase-activated protein kinase 2	Homo sapiens		 5.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688975	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688975&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542324	504490642							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433792	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(CN3CCOCC3)c2C)C(=O)N1	InChI=1S/C28H29N5O2S/c1-4-18-13-20(17(3)23(31-18)15-33-9-11-35-12-10-33)22-6-5-19-21(32-22)7-8-24-25(19)26-27(36-24)28(34)30-16(2)14-29-26/h4-8,13,16,29H,1,9-12,14-15H2,2-3H3,(H,30,34)/t16-/m1/s1	WZSXICVKZNTBRR-MRXNPFEDSA-N	688976	(R)-10-methyl-3-(3-methyl-2-(morpholinomethyl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-197	MAP kinase-activated protein kinase 2	Homo sapiens		 5.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688976	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688976&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430115	504490643							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433793	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(CN3CCOCC3)c2F)C(=O)N1	InChI=1S/C27H26FN5O2S/c1-3-16-12-18(24(28)21(31-16)14-33-8-10-35-11-9-33)20-5-4-17-19(32-20)6-7-22-23(17)25-26(36-22)27(34)30-15(2)13-29-25/h3-7,12,15,29H,1,8-11,13-14H2,2H3,(H,30,34)/t15-/m1/s1	LJHFRSVTIZPUPW-OAHLLOKOSA-N	688977	(R)-3-(3-fluoro-2-(morpholinomethyl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-198	MAP kinase-activated protein kinase 2	Homo sapiens		 106							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688977	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688977&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542358	504490644							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433794	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(\C=C\C(F)(F)F)c2)C(=O)N1	InChI=1S/C23H17F3N4OS/c1-12-11-28-20-19-15-2-3-16(13-7-9-27-14(10-13)6-8-23(24,25)26)30-17(15)4-5-18(19)32-21(20)22(31)29-12/h2-10,12,28H,11H2,1H3,(H,29,31)/b8-6+/t12-/m1/s1	YXOPJQJMANNZIN-WAFBPQNNSA-N	688978	(R,E)-10-methyl-3-(2-(3,3,3-trifluoroprop-1-en-1-yl)pyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-199	MAP kinase-activated protein kinase 2	Homo sapiens		 636							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688978	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688978&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430116	504490645							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433795	COc1nnc(\C=C\C(F)(F)F)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H18F3N5O2S/c1-11-10-27-19-18-13-3-4-16(29-15(13)5-6-17(18)34-20(19)21(32)28-11)14-9-12(7-8-23(24,25)26)30-31-22(14)33-2/h3-9,11,27H,10H2,1-2H3,(H,28,32)/b8-7+/t11-/m1/s1	XDFJMHAEAZCCGR-WSKFYRRCSA-N	688979	(R,E)-3-(3-methoxy-6-(3,3,3-trifluoroprop-1-en-1-yl)pyridazin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-200	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688979	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688979&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430117	504490646							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433796	CC1CN(CC(C)O1)c1cc(cc(C=C)n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C28H29N5O2S/c1-5-19-10-18(11-24(31-19)33-13-16(3)35-17(4)14-33)21-7-6-20-22(32-21)8-9-23-25(20)26-27(36-23)28(34)30-15(2)12-29-26/h5-11,15-17,29H,1,12-14H2,2-4H3,(H,30,34)/t15-,16?,17?/m1/s1	VCVUNZBNQDDTPL-KLAILNCOSA-N	688980	(10R)-3-(2-(2,6-dimethylmorpholino)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-201	MAP kinase-activated protein kinase 2	Homo sapiens		 73.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688980	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688980&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430118	504490647							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433797	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCC(CC2)C(F)(F)F)C(=O)N1	InChI=1S/C28H26F3N5OS/c1-3-18-12-16(13-23(34-18)36-10-8-17(9-11-36)28(29,30)31)20-5-4-19-21(35-20)6-7-22-24(19)25-26(38-22)27(37)33-15(2)14-32-25/h3-7,12-13,15,17,32H,1,8-11,14H2,2H3,(H,33,37)/t15-/m1/s1	ZDIUGIUAQKVSJL-OAHLLOKOSA-N	688981	(R)-10-methyl-3-(2-(4-(trifluoromethyl)piperidin-1-yl)-6-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-202	MAP kinase-activated protein kinase 2	Homo sapiens		 674							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688981	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688981&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430119	504490648							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433798	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2cnnc2C=C)C(=O)N1	InChI=1S/C19H16N6OS/c1-3-14-24-21-9-25(14)15-7-4-11-12(23-15)5-6-13-16(11)17-18(27-13)19(26)22-10(2)8-20-17/h3-7,9-10,20H,1,8H2,2H3,(H,22,26)/t10-/m1/s1	XHPLWICZTMVVSM-SNVBAGLBSA-N	688982	(R)-10-methyl-3-(3-vinyl-4H-1,2,4-triazol-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-203	MAP kinase-activated protein kinase 2	Homo sapiens		 9.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688982	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688982&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542106	504490649							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433799	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2cnnc2C#C)C(=O)N1	InChI=1S/C19H14N6OS/c1-3-14-24-21-9-25(14)15-7-4-11-12(23-15)5-6-13-16(11)17-18(27-13)19(26)22-10(2)8-20-17/h1,4-7,9-10,20H,8H2,2H3,(H,22,26)/t10-/m1/s1	MISUSVXJPXSDHX-SNVBAGLBSA-N	688983	(R)-3-(3-ethynyl-4H-1,2,4-triazol-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-204	MAP kinase-activated protein kinase 2	Homo sapiens		 555							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688983	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688983&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542362	504490650							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433800	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2ccnc2Cl)C(=O)N1	InChI=1S/C18H14ClN5OS/c1-9-8-21-15-14-10-2-5-13(24-7-6-20-18(24)19)23-11(10)3-4-12(14)26-16(15)17(25)22-9/h2-7,9,21H,8H2,1H3,(H,22,25)/t9-/m1/s1	LAVPUEOHZHZXHL-SECBINFHSA-N	688984	(R)-3-(2-chloro-1H-imidazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-205	MAP kinase-activated protein kinase 2	Homo sapiens		 97.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688984	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688984&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541893	504490651							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433801	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2cc(C)nc2C=C)C(=O)N1	InChI=1S/C21H19N5OS/c1-4-16-23-12(3)10-26(16)17-8-5-13-14(25-17)6-7-15-18(13)19-20(28-15)21(27)24-11(2)9-22-19/h4-8,10-11,22H,1,9H2,2-3H3,(H,24,27)/t11-/m1/s1	XVMDXYYSTFZQTH-LLVKDONJSA-N	688985	(R)-10-methyl-3-(4-methyl-2-vinyl-1H-imidazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-206	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688985	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688985&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542026	504490652							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433802	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2cnc(C=C)n2)C(=O)N1	InChI=1S/C19H16N6OS/c1-3-14-21-9-25(24-14)15-7-4-11-12(23-15)5-6-13-16(11)17-18(27-13)19(26)22-10(2)8-20-17/h3-7,9-10,20H,1,8H2,2H3,(H,22,26)/t10-/m1/s1	PBRQYJZUSAFOSL-SNVBAGLBSA-N	688986	(R)-10-methyl-3-(3-vinyl-1H-1,2,4-triazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-207	MAP kinase-activated protein kinase 2	Homo sapiens		 26.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688986	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688986&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542281	504490653							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433803	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(C=C)n(C)n2)C(=O)N1	InChI=1S/C20H18N6OS/c1-4-15-24-19(25-26(15)3)13-6-5-11-12(23-13)7-8-14-16(11)17-18(28-14)20(27)22-10(2)9-21-17/h4-8,10,21H,1,9H2,2-3H3,(H,22,27)/t10-/m1/s1	ZSCSLCKMRFAWJW-SNVBAGLBSA-N	688987	(R)-10-methyl-3-(1-methyl-5-vinyl-1H-1,2,4-triazol-3-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-208	MAP kinase-activated protein kinase 2	Homo sapiens		 285							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688987	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688987&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541926	504490654							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433804	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnc(C=C)s2)C(=O)N1	InChI=1S/C20H16N4OS2/c1-3-16-21-9-15(26-16)13-5-4-11-12(24-13)6-7-14-17(11)18-19(27-14)20(25)23-10(2)8-22-18/h3-7,9-10,22H,1,8H2,2H3,(H,23,25)/t10-/m1/s1	YXQRQGBIXITQKS-SNVBAGLBSA-N	688988	(R)-10-methyl-3-(2-vinylthiazol-5-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-209	MAP kinase-activated protein kinase 2	Homo sapiens		 15.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688988	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688988&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542043	504490655							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433805	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2cnc(Cl)n2)C(=O)N1	InChI=1S/C17H13ClN6OS/c1-8-6-19-14-13-9-2-5-12(24-7-20-17(18)23-24)22-10(9)3-4-11(13)26-15(14)16(25)21-8/h2-5,7-8,19H,6H2,1H3,(H,21,25)/t8-/m1/s1	CVUUBBVPJBBIAA-MRVPVSSYSA-N	688989	(R)-3-(3-chloro-1H-1,2,4-triazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-210	MAP kinase-activated protein kinase 2	Homo sapiens		 91.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688989	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688989&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541953	504490656							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433806	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2CN2CC(F)(F)C2)C(=O)N1	InChI=1S/C26H23F2N5OS/c1-3-16-8-18(15(10-29-16)11-33-12-26(27,28)13-33)20-5-4-17-19(32-20)6-7-21-22(17)23-24(35-21)25(34)31-14(2)9-30-23/h3-8,10,14,30H,1,9,11-13H2,2H3,(H,31,34)/t14-/m1/s1	MCERVZUXHAZFRL-CQSZACIVSA-N	688990	(R)-3-(5-((3,3-difluoroazetidin-1-yl)methyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-211	MAP kinase-activated protein kinase 2	Homo sapiens		 275							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688990	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688990&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430120	504490657							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433807	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2CN2CCC(CC2)C(F)(F)F)C(=O)N1	InChI=1S/C29H28F3N5OS/c1-3-19-12-21(17(14-33-19)15-37-10-8-18(9-11-37)29(30,31)32)23-5-4-20-22(36-23)6-7-24-25(20)26-27(39-24)28(38)35-16(2)13-34-26/h3-7,12,14,16,18,34H,1,8-11,13,15H2,2H3,(H,35,38)/t16-/m1/s1	SSFNJUJYWWRSBQ-MRXNPFEDSA-N	688991	(R)-10-methyl-3-(5-((4-(trifluoromethyl)piperidin-1-yl)methyl)-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-212	MAP kinase-activated protein kinase 2	Homo sapiens		 92.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688991	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688991&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430121	504490658							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433808	C[C@H]1CN(Cc2cnc(C=C)cc2-c2ccc3c4c5NC[C@@H](C)NC(=O)c5sc4ccc3n2)C[C@@H](C)O1	InChI=1S/C29H31N5O2S/c1-5-20-10-22(19(12-30-20)15-34-13-17(3)36-18(4)14-34)24-7-6-21-23(33-24)8-9-25-26(21)27-28(37-25)29(35)32-16(2)11-31-27/h5-10,12,16-18,31H,1,11,13-15H2,2-4H3,(H,32,35)/t16-,17-,18+/m1/s1	MIHWKVZJXVWLBK-KURKYZTESA-N	688992	(R)-3-(5-(((2S,6R)-2,6-dimethylmorpholino)methyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-213	MAP kinase-activated protein kinase 2	Homo sapiens		 103							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688992	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688992&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430122	504490659							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433809	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2ncnc2C=C)C(=O)N1	InChI=1S/C19H16N6OS/c1-3-14-21-9-22-25(14)15-7-4-11-12(24-15)5-6-13-16(11)17-18(27-13)19(26)23-10(2)8-20-17/h3-7,9-10,20H,1,8H2,2H3,(H,23,26)/t10-/m1/s1	KTARDXLFOUDLII-SNVBAGLBSA-N	688993	(R)-10-methyl-3-(5-vinyl-1H-1,2,4-triazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-214	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688993	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688993&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541960	504490660							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433810	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCC3(CCC(=O)O3)CC2)C(=O)N1	InChI=1S/C30H29N5O3S/c1-3-19-14-18(15-24(33-19)35-12-10-30(11-13-35)9-8-25(36)38-30)21-5-4-20-22(34-21)6-7-23-26(20)27-28(39-23)29(37)32-17(2)16-31-27/h3-7,14-15,17,31H,1,8-13,16H2,2H3,(H,32,37)/t17-/m1/s1	KQJGVWLJDNPNKM-QGZVFWFLSA-N	688994	US20240190890, Compound I-215::rac-(R)-8-(4-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)-6-vinylpyridin-2-yl)-1-oxa-8-azaspiro[4.5]decan-2-one	MAP kinase-activated protein kinase 2	Homo sapiens		 21.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688994	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688994&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430123	504490661							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433811	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CC3CC2CO3)C(=O)N1	InChI=1S/C27H25N5O2S/c1-3-16-8-15(9-23(30-16)32-12-18-10-17(32)13-34-18)20-5-4-19-21(31-20)6-7-22-24(19)25-26(35-22)27(33)29-14(2)11-28-25/h3-9,14,17-18,28H,1,10-13H2,2H3,(H,29,33)/t14-,17?,18?/m1/s1	UAUDQYZVWMPVJD-RWBZWWBESA-N	688995	US20240190890, Compound I-216::rac-(10R)-3-(2-(2-oxa-5-azabicyclo[2.2.1]heptan-5-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one	MAP kinase-activated protein kinase 2	Homo sapiens		 11.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688995	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688995&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430124	504490662							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433812	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(C=C)c2F)C(=O)N1	InChI=1S/C22H17FN4OS/c1-3-14-19(23)13(8-9-24-14)16-5-4-12-15(27-16)6-7-17-18(12)20-21(29-17)22(28)26-11(2)10-25-20/h3-9,11,25H,1,10H2,2H3,(H,26,28)/t11-/m1/s1	YRFPAEXAHRVQAJ-LLVKDONJSA-N	688996	(R)-3-(3-fluoro-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-217	MAP kinase-activated protein kinase 2	Homo sapiens		 78.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688996	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688996&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542304	504490663							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433813	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(C#C)c2F)C(=O)N1	InChI=1S/C22H15FN4OS/c1-3-14-19(23)13(8-9-24-14)16-5-4-12-15(27-16)6-7-17-18(12)20-21(29-17)22(28)26-11(2)10-25-20/h1,4-9,11,25H,10H2,2H3,(H,26,28)/t11-/m1/s1	KBWOMRYXMQGXKZ-LLVKDONJSA-N	688997	(R)-3-(2-ethynyl-3-fluoropyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-218	MAP kinase-activated protein kinase 2	Homo sapiens		 79.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688997	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688997&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541891	504490664							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433814	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(C=C)c2C)C(=O)N1	InChI=1S/C23H20N4OS/c1-4-16-13(3)14(9-10-24-16)17-6-5-15-18(27-17)7-8-19-20(15)21-22(29-19)23(28)26-12(2)11-25-21/h4-10,12,25H,1,11H2,2-3H3,(H,26,28)/t12-/m1/s1	VXLLOQZNXCQVKJ-GFCCVEGCSA-N	688998	(R)-10-methyl-3-(3-methyl-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-219	MAP kinase-activated protein kinase 2	Homo sapiens		 142							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688998	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688998&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542371	504490665							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433815	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(C#C)c2C)C(=O)N1	InChI=1S/C23H18N4OS/c1-4-16-13(3)14(9-10-24-16)17-6-5-15-18(27-17)7-8-19-20(15)21-22(29-19)23(28)26-12(2)11-25-21/h1,5-10,12,25H,11H2,2-3H3,(H,26,28)/t12-/m1/s1	CIFRNJAUIKCJJY-GFCCVEGCSA-N	688999	(R)-3-(2-ethynyl-3-methylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-220	MAP kinase-activated protein kinase 2	Homo sapiens		 177							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688999	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688999&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542024	504490666							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433816	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(Cl)c2F)C(=O)N1	InChI=1S/C20H14ClFN4OS/c1-9-8-24-17-15-10-2-3-13(11-6-7-23-19(21)16(11)22)26-12(10)4-5-14(15)28-18(17)20(27)25-9/h2-7,9,24H,8H2,1H3,(H,25,27)/t9-/m1/s1	GUAWBFMSCCGCHD-SECBINFHSA-N	689000	(R)-3-(2-chloro-3-fluoropyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-221	MAP kinase-activated protein kinase 2	Homo sapiens		 212							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689000	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689000&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542005	504490667							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433817	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2c(C)nnc2C=C)C(=O)N1	InChI=1S/C20H18N6OS/c1-4-15-25-24-11(3)26(15)16-8-5-12-13(23-16)6-7-14-17(12)18-19(28-14)20(27)22-10(2)9-21-18/h4-8,10,21H,1,9H2,2-3H3,(H,22,27)/t10-/m1/s1	UKZIWSCAZRXXEI-SNVBAGLBSA-N	689001	(R)-10-methyl-3-(3-methyl-5-vinyl-4H-1,2,4-triazol-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-223	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689001	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689001&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542390	504490668							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433818	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2nc(C)nc2C=C)C(=O)N1	InChI=1S/C20H18N6OS/c1-4-15-23-11(3)25-26(15)16-8-5-12-13(24-16)6-7-14-17(12)18-19(28-14)20(27)22-10(2)9-21-18/h4-8,10,21H,1,9H2,2-3H3,(H,22,27)/t10-/m1/s1	VUTLURZCMHNLEM-SNVBAGLBSA-N	689002	(R)-10-methyl-3-(3-methyl-5-vinyl-1H-1,2,4-triazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-224	MAP kinase-activated protein kinase 2	Homo sapiens		 2.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689002	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689002&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542386	504490669							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433819	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cncc(n2)C(=C)C(F)(F)F)C(=O)N1	InChI=1S/C22H16F3N5OS/c1-10-7-27-19-18-12-3-4-14(16-9-26-8-15(30-16)11(2)22(23,24)25)29-13(12)5-6-17(18)32-20(19)21(31)28-10/h3-6,8-10,27H,2,7H2,1H3,(H,28,31)/t10-/m1/s1	RJKNHNIUOBIRNC-SNVBAGLBSA-N	689003	(R)-10-methyl-3-(6-(3,3,3-trifluoroprop-1-en-2-yl)pyrazin-2-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-225	MAP kinase-activated protein kinase 2	Homo sapiens		 19.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689003	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689003&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430125	504490670							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433820	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2nc(nc2C=C)C(F)(F)F)C(=O)N1	InChI=1S/C20H15F3N6OS/c1-3-13-27-19(20(21,22)23)28-29(13)14-7-4-10-11(26-14)5-6-12-15(10)16-17(31-12)18(30)25-9(2)8-24-16/h3-7,9,24H,1,8H2,2H3,(H,25,30)/t9-/m1/s1	BOXZFQDKAUZSHQ-SECBINFHSA-N	689004	(R)-10-methyl-3-(3-(trifluoromethyl)-5-vinyl-1H-1,2,4-triazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-226	MAP kinase-activated protein kinase 2	Homo sapiens		 7.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689004	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689004&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430126	504490671							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433821	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2c(C)onc2C=C)C(=O)N1	InChI=1S/C21H18N4O2S/c1-4-13-17(11(3)27-25-13)15-6-5-12-14(24-15)7-8-16-18(12)19-20(28-16)21(26)23-10(2)9-22-19/h4-8,10,22H,1,9H2,2-3H3,(H,23,26)/t10-/m1/s1	GFIPJSOTFOBQQO-SNVBAGLBSA-N	689005	(R)-10-methyl-3-(5-methyl-3-vinylisoxazol-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-227	MAP kinase-activated protein kinase 2	Homo sapiens		 418							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689005	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689005&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542247	504490672							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433822	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2csnc2C=C)C(=O)N1	InChI=1S/C20H16N4OS2/c1-3-13-12(9-26-24-13)15-5-4-11-14(23-15)6-7-16-17(11)18-19(27-16)20(25)22-10(2)8-21-18/h3-7,9-10,21H,1,8H2,2H3,(H,22,25)/t10-/m1/s1	YROLAJRIDRCTHN-SNVBAGLBSA-N	689006	(R)-10-methyl-3-(3-vinylisothiazol-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-228	MAP kinase-activated protein kinase 2	Homo sapiens		 128							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689006	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689006&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541881	504490673							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433823	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cnsc2C=C)C(=O)N1	InChI=1S/C20H16N4OS2/c1-3-15-12(9-22-27-15)14-5-4-11-13(24-14)6-7-16-17(11)18-19(26-16)20(25)23-10(2)8-21-18/h3-7,9-10,21H,1,8H2,2H3,(H,23,25)/t10-/m1/s1	FWJPLVJMCVPIIM-SNVBAGLBSA-N	689007	(R)-10-methyl-3-(5-vinylisothiazol-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-229	MAP kinase-activated protein kinase 2	Homo sapiens		 123							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689007	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689007&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542123	504490674							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433824	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cn(C)nc2C=C)C(=O)N1	InChI=1S/C21H19N5OS/c1-4-14-13(10-26(3)25-14)16-6-5-12-15(24-16)7-8-17-18(12)19-20(28-17)21(27)23-11(2)9-22-19/h4-8,10-11,22H,1,9H2,2-3H3,(H,23,27)/t11-/m1/s1	ZDMAZGAXWIRRFZ-LLVKDONJSA-N	689008	(R)-10-methyl-3-(1-methyl-3-vinyl-1H-pyrazol-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-230	MAP kinase-activated protein kinase 2	Homo sapiens		 44.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689008	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689008&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542306	504490675							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433825	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2c(C)c(C)nc2C=C)C(=O)N1	InChI=1S/C22H21N5OS/c1-5-17-25-12(3)13(4)27(17)18-9-6-14-15(26-18)7-8-16-19(14)20-21(29-16)22(28)24-11(2)10-23-20/h5-9,11,23H,1,10H2,2-4H3,(H,24,28)/t11-/m1/s1	OFISPFUCPAUNPH-LLVKDONJSA-N	689009	(R)-3-(4,5-dimethyl-2-vinyl-1H-imidazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-231	MAP kinase-activated protein kinase 2	Homo sapiens		 28.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689009	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689009&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541899	504490676							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433826	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nn(C)nc2C=C)C(=O)N1	InChI=1S/C20H18N6OS/c1-4-12-17(25-26(3)24-12)14-6-5-11-13(23-14)7-8-15-16(11)18-19(28-15)20(27)22-10(2)9-21-18/h4-8,10,21H,1,9H2,2-3H3,(H,22,27)/t10-/m1/s1	PFEDHUGTYWLHKM-SNVBAGLBSA-N	689010	(R)-10-methyl-3-(2-methyl-5-vinyl-2H-1,2,3-triazol-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-232	MAP kinase-activated protein kinase 2	Homo sapiens		 77.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689010	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689010&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542316	504490677							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433827	CCOC(=O)c1nc(C=C)sc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H20N4O3S2/c1-4-16-27-19(23(29)30-5-2)20(32-16)14-7-6-12-13(26-14)8-9-15-17(12)18-21(31-15)22(28)25-11(3)10-24-18/h4,6-9,11,24H,1,5,10H2,2-3H3,(H,25,28)/t11-/m1/s1	UQIHHBRHOCFGJA-LLVKDONJSA-N	689011	US20240190890, Compound I-234::ethyl (R)-5-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)-2-vinylthiazole-4-carboxylate	MAP kinase-activated protein kinase 2	Homo sapiens		 18.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689011	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689011&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430127	504490678							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433828	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2nc(C)cc2C=C)C(=O)N1	InChI=1S/C21H19N5OS/c1-4-13-9-11(2)25-26(13)17-8-5-14-15(24-17)6-7-16-18(14)19-20(28-16)21(27)23-12(3)10-22-19/h4-9,12,22H,1,10H2,2-3H3,(H,23,27)/t12-/m1/s1	DESNTIRKVMGXJP-GFCCVEGCSA-N	689012	(R)-10-methyl-3-(3-methyl-5-vinyl-1H-pyrazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-236	MAP kinase-activated protein kinase 2	Homo sapiens		 157							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689012	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689012&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542287	504490679							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433829	COCCN(C)c1cc(cc(C=C)n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C26H27N5O2S/c1-5-17-12-16(13-22(29-17)31(3)10-11-33-4)19-7-6-18-20(30-19)8-9-21-23(18)24-25(34-21)26(32)28-15(2)14-27-24/h5-9,12-13,15,27H,1,10-11,14H2,2-4H3,(H,28,32)/t15-/m1/s1	AUJUEFHDCSGTFS-OAHLLOKOSA-N	689013	(R)-3-(2-((2-methoxyethyl)(methyl)amino)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-237	MAP kinase-activated protein kinase 2	Homo sapiens		 10.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689013	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689013&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430128	504490680							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433830	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CC3(COC3)C2)C(=O)N1	InChI=1S/C27H25N5O2S/c1-3-17-8-16(9-22(30-17)32-11-27(12-32)13-34-14-27)19-5-4-18-20(31-19)6-7-21-23(18)24-25(35-21)26(33)29-15(2)10-28-24/h3-9,15,28H,1,10-14H2,2H3,(H,29,33)/t15-/m1/s1	ASURDSIOGDRSOE-OAHLLOKOSA-N	689014	(R)-3-(2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-238	MAP kinase-activated protein kinase 2	Homo sapiens		 6.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689014	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689014&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430129	504490681							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433831	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)nc(c2)N2CCC(F)CC2)C(=O)N1	InChI=1S/C27H26FN5OS/c1-3-18-12-16(13-23(31-18)33-10-8-17(28)9-11-33)20-5-4-19-21(32-20)6-7-22-24(19)25-26(35-22)27(34)30-15(2)14-29-25/h3-7,12-13,15,17,29H,1,8-11,14H2,2H3,(H,30,34)/t15-/m1/s1	OOLAHQMTYLXGOV-OAHLLOKOSA-N	689015	(R)-3-(2-(4-fluoropiperidin-1-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-239	MAP kinase-activated protein kinase 2	Homo sapiens		 161							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689015	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689015&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430130	504490682							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433832	COCC1CCN(CC1)c1cc(cc(C=C)n1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C29H31N5O2S/c1-4-20-13-19(14-25(32-20)34-11-9-18(10-12-34)16-36-3)22-6-5-21-23(33-22)7-8-24-26(21)27-28(37-24)29(35)31-17(2)15-30-27/h4-8,13-14,17-18,30H,1,9-12,15-16H2,2-3H3,(H,31,35)/t17-/m1/s1	IJKGBBSQAMWFCM-QGZVFWFLSA-N	689016	(R)-3-(2-(4-(methoxymethyl)piperidin-1-yl)-6-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-240	MAP kinase-activated protein kinase 2	Homo sapiens		 107							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689016	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689016&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430131	504490683							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433833	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2nc(cc2C=C)C(F)(F)F)C(=O)N1	InChI=1S/C21H16F3N5OS/c1-3-11-8-15(21(22,23)24)28-29(11)16-7-4-12-13(27-16)5-6-14-17(12)18-19(31-14)20(30)26-10(2)9-25-18/h3-8,10,25H,1,9H2,2H3,(H,26,30)/t10-/m1/s1	OQUFOXRXEOUVSZ-SNVBAGLBSA-N	689017	(R)-10-methyl-3-(3-(trifluoromethyl)-5-vinyl-1H-pyrazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-241	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689017	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689017&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430132	504490684							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433834	CC(O)c1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H22N4O2S/c1-4-14-9-16(17(11-25-14)13(3)29)19-6-5-15-18(28-19)7-8-20-21(15)22-23(31-20)24(30)27-12(2)10-26-22/h4-9,11-13,26,29H,1,10H2,2-3H3,(H,27,30)/t12-,13?/m1/s1	VFJDQMVTKRWATQ-PZORYLMUSA-N	689018	(10R)-3-(5-(1-hydroxyethyl-2,2,2-d3)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-243::US20240190890, Compound I-259::US20240190890, Compound I-260	MAP kinase-activated protein kinase 2	Homo sapiens		 10.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689018&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430133	504490685							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433835	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2OC(F)(F)F)C(=O)N1	InChI=1S/C23H17F3N4O2S/c1-3-12-8-14(17(10-27-12)32-23(24,25)26)16-5-4-13-15(30-16)6-7-18-19(13)20-21(33-18)22(31)29-11(2)9-28-20/h3-8,10-11,28H,1,9H2,2H3,(H,29,31)/t11-/m1/s1	XEOGGXBBCXQFGX-LLVKDONJSA-N	689019	(R)-10-methyl-3-(5-(trifluoromethoxy)-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-245	MAP kinase-activated protein kinase 2	Homo sapiens		 74.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689019	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689019&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542346	504490686							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433836	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2ccnc2C#N)C(=O)N1	InChI=1S/C19H14N6OS/c1-10-9-22-17-16-11-2-5-14(25-7-6-21-15(25)8-20)24-12(11)3-4-13(16)27-18(17)19(26)23-10/h2-7,10,22H,9H2,1H3,(H,23,26)/t10-/m1/s1	LOQSQKXHEBPWDV-SNVBAGLBSA-N	689020	(R)-1-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)-1H-imidazole-2-carbonitrile::US20240190890, Compound I-246	MAP kinase-activated protein kinase 2	Homo sapiens		 16.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689020	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689020&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430134	504490687							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433837	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2OC(F)F)C(=O)N1	InChI=1S/C23H18F2N4O2S/c1-3-12-8-14(17(10-26-12)31-23(24)25)16-5-4-13-15(29-16)6-7-18-19(13)20-21(32-18)22(30)28-11(2)9-27-20/h3-8,10-11,23,27H,1,9H2,2H3,(H,28,30)/t11-/m1/s1	WGMUJTDZRYAMKW-LLVKDONJSA-N	689021	(R)-3-(5-(difluoromethoxy)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-247	MAP kinase-activated protein kinase 2	Homo sapiens		 360							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689021	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689021&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541902	504490688							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433838	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2nc(C=C)nc2C2CC2)C(=O)N1	InChI=1S/C22H20N6OS/c1-3-16-26-21(12-4-5-12)28(27-16)17-9-6-13-14(25-17)7-8-15-18(13)19-20(30-15)22(29)24-11(2)10-23-19/h3,6-9,11-12,23H,1,4-5,10H2,2H3,(H,24,29)/t11-/m1/s1	JJBXUBXKMQQEEZ-LLVKDONJSA-N	689022	(R)-3-(5-cyclopropyl-3-vinyl-1H-1,2,4-triazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-248	MAP kinase-activated protein kinase 2	Homo sapiens		 303							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689022	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689022&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430135	504490689							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433839	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2C)C(=O)N1	InChI=1S/C23H20N4OS/c1-4-14-9-16(12(2)10-24-14)18-6-5-15-17(27-18)7-8-19-20(15)21-22(29-19)23(28)26-13(3)11-25-21/h4-10,13,25H,1,11H2,2-3H3,(H,26,28)/t13-/m1/s1	UIPAEGAJTRBGJU-CYBMUJFWSA-N	688889	(R)-10-methyl-3-(5-methyl-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-109::US20240190890, Compound I-142::US20240190890, Compound I-249	MAP kinase-activated protein kinase 2	Homo sapiens		 4.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=688889	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=688889&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541925	504490559							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433840	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2c(Br)nc(Cl)c2Cl)C(=O)N1	InChI=1S/C18H12BrCl2N5OS/c1-7-6-22-13-12-8-2-5-11(26-16(21)15(20)25-18(26)19)24-9(8)3-4-10(12)28-14(13)17(27)23-7/h2-5,7,22H,6H2,1H3,(H,23,27)/t7-/m1/s1	GVDDEQIBMJZDQH-SSDOTTSWSA-N	689024	(R)-3-(2-bromo-4,5-dichloro-1H-imidazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-250	MAP kinase-activated protein kinase 2	Homo sapiens		 580							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689024	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689024&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542216	504490690							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433841	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2c(Cl)c(Cl)nc2C=C)C(=O)N1	InChI=1S/C20H15Cl2N5OS/c1-3-13-26-18(21)19(22)27(13)14-7-4-10-11(25-14)5-6-12-15(10)16-17(29-12)20(28)24-9(2)8-23-16/h3-7,9,23H,1,8H2,2H3,(H,24,28)/t9-/m1/s1	CWKNACSIGSOEQY-SECBINFHSA-N	689025	(R)-3-(4,5-dichloro-2-vinyl-1H-imidazol-1-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-251	MAP kinase-activated protein kinase 2	Homo sapiens		 192							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689025	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689025&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542198	504490691							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433842	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2CO)C(=O)N1	InChI=1S/C23H20N4O2S/c1-3-14-8-16(13(11-28)10-24-14)18-5-4-15-17(27-18)6-7-19-20(15)21-22(30-19)23(29)26-12(2)9-25-21/h3-8,10,12,25,28H,1,9,11H2,2H3,(H,26,29)/t12-/m1/s1	NULHKZXNEJFIJI-GFCCVEGCSA-N	689026	(R)-3-(5-(hydroxymethyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-252	MAP kinase-activated protein kinase 2	Homo sapiens		 5.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689026	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689026&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542237	504490692							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433843	COCc1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H22N4O2S/c1-4-15-9-17(14(11-25-15)12-30-3)19-6-5-16-18(28-19)7-8-20-21(16)22-23(31-20)24(29)27-13(2)10-26-22/h4-9,11,13,26H,1,10,12H2,2-3H3,(H,27,29)/t13-/m1/s1	PPVBAYFMTXCFBK-CYBMUJFWSA-N	689027	(R)-3-(5-(methoxymethyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-253	MAP kinase-activated protein kinase 2	Homo sapiens		 6.00							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689027	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689027&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542173	504490693							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433844	Cc1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](CF)NC(=O)c4sc3ccc2n1	InChI=1S/C23H19FN4OS/c1-3-13-8-16(12(2)10-25-13)18-5-4-15-17(28-18)6-7-19-20(15)21-22(30-19)23(29)27-14(9-24)11-26-21/h3-8,10,14,26H,1,9,11H2,2H3,(H,27,29)/t14-/m1/s1	RQKOWASNNKJWNZ-CQSZACIVSA-N	689028	(S)-10-(fluoromethyl)-3-(5-methyl-2-vinylpyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-254	MAP kinase-activated protein kinase 2	Homo sapiens		 27.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689028	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689028&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542272	504490694							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433845	FC[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2ccnc2C=C)C(=O)N1	InChI=1S/C20H16FN5OS/c1-2-15-22-7-8-26(15)16-6-3-12-13(25-16)4-5-14-17(12)18-19(28-14)20(27)24-11(9-21)10-23-18/h2-8,11,23H,1,9-10H2,(H,24,27)/t11-/m1/s1	RUCYWKIPKMCRTR-LLVKDONJSA-N	689029	(S)-10-(fluoromethyl)-3-(2-vinyl-1H-imidazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-255	MAP kinase-activated protein kinase 2	Homo sapiens		 1.000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689029	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689029&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542021	504490695							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433846	COc1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C23H20N4O2S/c1-4-13-9-15(18(29-3)11-24-13)17-6-5-14-16(27-17)7-8-19-20(14)21-22(30-19)23(28)26-12(2)10-25-21/h4-9,11-12,25H,1,10H2,2-3H3,(H,26,28)/t12-/m1/s1	YTRUKNWXEGTQQV-GFCCVEGCSA-N	689030	(R)-3-(5-methoxy-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-256	MAP kinase-activated protein kinase 2	Homo sapiens		 20.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689030	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689030&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542330	504490696							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433847	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2nc(C=C)cc2C(F)(F)F)C(=O)N1	InChI=1S/C21H16F3N5OS/c1-3-11-8-15(21(22,23)24)29(28-11)16-7-4-12-13(27-16)5-6-14-17(12)18-19(31-14)20(30)26-10(2)9-25-18/h3-8,10,25H,1,9H2,2H3,(H,26,30)/t10-/m1/s1	PBZXBBSSSREFEM-SNVBAGLBSA-N	689031	(R)-10-methyl-3-(5-(trifluoromethyl)-3-vinyl-1H-pyrazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-257	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689031	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689031&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430136	504490697							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433848	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2C(C)(C)O)C(=O)N1	InChI=1S/C25H24N4O2S/c1-5-14-10-16(17(12-26-14)25(3,4)31)19-7-6-15-18(29-19)8-9-20-21(15)22-23(32-20)24(30)28-13(2)11-27-22/h5-10,12-13,27,31H,1,11H2,2-4H3,(H,28,30)/t13-/m1/s1	LRVKCNGADNPVEK-CYBMUJFWSA-N	689032	(R)-3-(5-(2-hydroxypropan-2-yl-1,1,1,3,3,3-d6)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-258	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689032	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689032&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430137	504490698							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433849	CC(O)c1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H22N4O2S/c1-4-14-9-16(17(11-25-14)13(3)29)19-6-5-15-18(28-19)7-8-20-21(15)22-23(31-20)24(30)27-12(2)10-26-22/h4-9,11-13,26,29H,1,10H2,2-3H3,(H,27,30)/t12-,13?/m1/s1	VFJDQMVTKRWATQ-PZORYLMUSA-N	689018	(10R)-3-(5-(1-hydroxyethyl-2,2,2-d3)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-243::US20240190890, Compound I-259::US20240190890, Compound I-260	MAP kinase-activated protein kinase 2	Homo sapiens		 15.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689018&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430133	504490685							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433850	CC(O)c1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H22N4O2S/c1-4-14-9-16(17(11-25-14)13(3)29)19-6-5-15-18(28-19)7-8-20-21(15)22-23(31-20)24(30)27-12(2)10-26-22/h4-9,11-13,26,29H,1,10H2,2-3H3,(H,27,30)/t12-,13?/m1/s1	VFJDQMVTKRWATQ-PZORYLMUSA-N	689018	(10R)-3-(5-(1-hydroxyethyl-2,2,2-d3)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-243::US20240190890, Compound I-259::US20240190890, Compound I-260	MAP kinase-activated protein kinase 2	Homo sapiens		 16.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689018	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689018&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430133	504490685							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433851	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-n2nc(C=C)nc2C)C(=O)N1	InChI=1S/C20H18N6OS/c1-4-15-23-11(3)26(25-15)16-8-5-12-13(24-16)6-7-14-17(12)18-19(28-14)20(27)22-10(2)9-21-18/h4-8,10,21H,1,9H2,2-3H3,(H,22,27)/t10-/m1/s1	KEYVMUGYNLEQQN-SNVBAGLBSA-N	689035	(R)-10-methyl-3-(5-methyl-3-vinyl-1H-1,2,4-triazol-1-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-261	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689035	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689035&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542336	504490699							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433852	CCOCc1cnc(C=C)cc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C25H24N4O2S/c1-4-16-10-18(15(12-26-16)13-31-5-2)20-7-6-17-19(29-20)8-9-21-22(17)23-24(32-21)25(30)28-14(3)11-27-23/h4,6-10,12,14,27H,1,5,11,13H2,2-3H3,(H,28,30)/t14-/m1/s1	NGFZCKQIKUTHIO-CQSZACIVSA-N	689036	(R)-3-(5-(ethoxymethyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-262	MAP kinase-activated protein kinase 2	Homo sapiens		 35.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689036	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689036&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171541997	504490700							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433853	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(C=C)ncc2CN2CC3(COC3)C2)C(=O)N1	InChI=1S/C28H27N5O2S/c1-3-18-8-20(17(10-29-18)11-33-12-28(13-33)14-35-15-28)22-5-4-19-21(32-22)6-7-23-24(19)25-26(36-23)27(34)31-16(2)9-30-25/h3-8,10,16,30H,1,9,11-15H2,2H3,(H,31,34)/t16-/m1/s1	LUJWAYPDJMBJRZ-MRXNPFEDSA-N	689037	(R)-3-(5-((2-oxa-6-azaspiro[3.3]heptan-6-yl)methyl)-2-vinylpyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-263	MAP kinase-activated protein kinase 2	Homo sapiens		 47.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689037	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689037&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430138	504490701							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433854	C\C=C\c1cc(c(C)cn1)-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1	InChI=1S/C24H22N4OS/c1-4-5-15-10-17(13(2)11-25-15)19-7-6-16-18(28-19)8-9-20-21(16)22-23(30-20)24(29)27-14(3)12-26-22/h4-11,14,26H,12H2,1-3H3,(H,27,29)/b5-4+/t14-/m1/s1	ATSXBIDTBWEJTA-ISZGNANSSA-N	689038	(R,E)-10-methyl-3-(5-methyl-2-(prop-1-en-1-yl)pyridin-4-yl)-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-265	MAP kinase-activated protein kinase 2	Homo sapiens		 210							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689038	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689038&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430139	504490702							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433855	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2cc(CC#N)ncc2C)C(=O)N1	InChI=1S/C23H19N5OS/c1-12-10-25-14(7-8-24)9-16(12)18-4-3-15-17(28-18)5-6-19-20(15)21-22(30-19)23(29)27-13(2)11-26-21/h3-6,9-10,13,26H,7,11H2,1-2H3,(H,27,29)/t13-/m1/s1	YLUGJWFTMUUAFR-CYBMUJFWSA-N	689039	(R)-2-(5-methyl-4-(10-methyl-8-oxo-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-3-yl)pyridin-2-yl)acetonitrile::US20240190890, Compound I-267	MAP kinase-activated protein kinase 2	Homo sapiens		 1000							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689039	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689039&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430140	504490703							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433856	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2ccnc(Cl)c2)C(=O)N1	InChI=1S/C20H15ClN4OS/c1-10-9-23-18-17-12-2-3-13(11-6-7-22-16(21)8-11)25-14(12)4-5-15(17)27-19(18)20(26)24-10/h2-8,10,23H,9H2,1H3,(H,24,26)/t10-/m1/s1	DXASXHJWKHLFQP-SNVBAGLBSA-N	689040	(R)-3-(2-chloropyridin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-272	MAP kinase-activated protein kinase 2	Homo sapiens		 68.0							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689040	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689040&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542360	504490704							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433857	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)ncc2F)C(=O)N1	InChI=1S/C19H13ClFN5OS/c1-8-6-22-16-14-9-2-3-12(15-10(21)7-23-19(20)26-15)25-11(9)4-5-13(14)28-17(16)18(27)24-8/h2-5,7-8,22H,6H2,1H3,(H,24,27)/t8-/m1/s1	CGVUZGKBSROPDO-MRVPVSSYSA-N	689041	(R)-3-(2-chloro-5-fluoropyrimidin-4-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-273	MAP kinase-activated protein kinase 2	Homo sapiens		 153							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689041	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689041&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			171542171	504490705							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6						
1433858	C[C@@H]1CNc2c(sc3ccc4nc(ccc4c23)-c2nc(Cl)c(cc2F)C(F)(F)F)C(=O)N1	InChI=1S/C21H13ClF4N4OS/c1-8-7-27-17-15-9-2-3-13(16-11(23)6-10(19(22)30-16)21(24,25)26)29-12(9)4-5-14(15)32-18(17)20(31)28-8/h2-6,8,27H,7H2,1H3,(H,28,31)/t8-/m1/s1	ADWBRORZUWWHKP-MRVPVSSYSA-N	689042	(R)-3-(6-chloro-3-fluoro-5-(trifluoromethyl)pyridin-2-yl)-10-methyl-9,10,11,12-tetrahydro-8H-[1,4]diazepino[5',6':4,5]thieno[3,2-f]quinolin-8-one::US20240190890, Compound I-274	MAP kinase-activated protein kinase 2	Homo sapiens		 752							US Patent		10.7270/Q2VX0MTW			US20240190890	Hu, X; Qiao, L; Seletsky, B; Patton, M; Cao, M; van der Mei, F; Miao, G; McDonald, I; Dzierba, C	Bristol-Myers Squibb Company; Celgene Corporation	http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=689042	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=pol&polymerid=3678&target=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search	http://www.bindingdb.org/jsp/dbsearch/PrimarySearch_ki.jsp?energyterm=kJ/mole&tag=r21&monomerid=689042&enzyme=MAP+kinase-activated+protein+kinase+2&column=ki&startPg=0&Increment=50&submit=Search			172430141	504490706							1	MLSNSQGQSPPVPFPAPAPPPQPPTPALPHPPAQPPPPPPQQFPQFHVKSGLQIKKNAIIDDYKVTSQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKARREVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQDRGDQAFTEREASEIMKSIGEAIQYLHSINIAHRDVKPENLLYTSKRPNAILKLTDFGFAKETTSHNSLTTPCYTPYYVAPEVLGPEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWIMQSTKVPQTPLHTSRVLKEDKERWEDVKEEMTSALATMRVDYEQIKIKKIEDASNPLLLKRRKKARALEAAALAH	2ONL,1NY3,1NXK,1KWP,6TCA,2OZA,4TYH,7NRY,3FYK,3FYJ,2P3G,2JBP,2JBO,3GOK,3WI6,3KC3,3FPM,3A2C,2PZY,3R30,3R2Y,3R2B	MAP kinase-activated protein kinase 2	MAPK2_HUMAN	P49137	Q5SY30 Q5SY41 Q8IYD6